Amino acid dipepetide frequency for Fusarium graminearum deltaflexivirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.201AlaAla: 11.201 ± 1.264
1.931AlaCys: 1.931 ± 0.906
4.249AlaAsp: 4.249 ± 1.519
2.704AlaGlu: 2.704 ± 0.779
3.862AlaPhe: 3.862 ± 1.102
4.249AlaGly: 4.249 ± 1.295
2.317AlaHis: 2.317 ± 1.571
1.159AlaIle: 1.159 ± 0.543
1.931AlaLys: 1.931 ± 0.603
9.27AlaLeu: 9.27 ± 2.238
1.931AlaMet: 1.931 ± 0.707
1.159AlaAsn: 1.159 ± 0.543
10.429AlaPro: 10.429 ± 2.106
2.704AlaGln: 2.704 ± 1.191
5.021AlaArg: 5.021 ± 2.023
7.339AlaSer: 7.339 ± 1.63
7.725AlaThr: 7.725 ± 2.194
8.111AlaVal: 8.111 ± 2.355
2.317AlaTrp: 2.317 ± 0.876
2.704AlaTyr: 2.704 ± 2.047
0.0AlaXaa: 0.0 ± 0.0
Cys
1.159CysAla: 1.159 ± 0.543
0.0CysCys: 0.0 ± 0.0
0.0CysAsp: 0.0 ± 0.0
0.386CysGlu: 0.386 ± 0.181
0.772CysPhe: 0.772 ± 1.032
0.386CysGly: 0.386 ± 0.181
0.386CysHis: 0.386 ± 0.181
1.545CysIle: 1.545 ± 0.584
0.0CysLys: 0.0 ± 0.0
0.772CysLeu: 0.772 ± 0.362
0.386CysMet: 0.386 ± 0.181
0.772CysAsn: 0.772 ± 0.362
0.772CysPro: 0.772 ± 0.362
0.386CysGln: 0.386 ± 0.181
0.386CysArg: 0.386 ± 0.181
0.772CysSer: 0.772 ± 0.362
0.0CysThr: 0.0 ± 0.0
1.545CysVal: 1.545 ± 0.725
1.545CysTrp: 1.545 ± 2.065
0.386CysTyr: 0.386 ± 0.181
0.0CysXaa: 0.0 ± 0.0
Asp
6.18AspAla: 6.18 ± 2.898
0.772AspCys: 0.772 ± 1.032
3.476AspAsp: 3.476 ± 1.055
1.545AspGlu: 1.545 ± 0.584
1.931AspPhe: 1.931 ± 0.906
1.931AspGly: 1.931 ± 0.603
0.772AspHis: 0.772 ± 0.987
3.09AspIle: 3.09 ± 0.935
1.545AspLys: 1.545 ± 0.699
4.635AspLeu: 4.635 ± 1.557
0.772AspMet: 0.772 ± 0.362
1.159AspAsn: 1.159 ± 0.785
4.249AspPro: 4.249 ± 1.803
0.386AspGln: 0.386 ± 0.181
2.317AspArg: 2.317 ± 0.876
3.476AspSer: 3.476 ± 1.254
4.249AspThr: 4.249 ± 3.247
6.566AspVal: 6.566 ± 3.08
0.386AspTrp: 0.386 ± 0.181
2.704AspTyr: 2.704 ± 0.938
0.0AspXaa: 0.0 ± 0.0
Glu
0.386GluAla: 0.386 ± 0.181
0.386GluCys: 0.386 ± 0.181
0.386GluAsp: 0.386 ± 0.181
0.772GluGlu: 0.772 ± 0.702
1.931GluPhe: 1.931 ± 1.92
1.931GluGly: 1.931 ± 0.653
1.931GluHis: 1.931 ± 2.709
0.386GluIle: 0.386 ± 1.091
0.772GluLys: 0.772 ± 0.362
1.931GluLeu: 1.931 ± 1.303
0.0GluMet: 0.0 ± 0.0
1.159GluAsn: 1.159 ± 1.45
2.317GluPro: 2.317 ± 1.087
0.772GluGln: 0.772 ± 0.362
1.159GluArg: 1.159 ± 0.543
0.772GluSer: 0.772 ± 0.362
2.704GluThr: 2.704 ± 0.938
2.704GluVal: 2.704 ± 0.779
1.545GluTrp: 1.545 ± 0.94
0.386GluTyr: 0.386 ± 0.181
0.0GluXaa: 0.0 ± 0.0
Phe
3.09PheAla: 3.09 ± 2.052
0.772PheCys: 0.772 ± 0.362
4.249PheAsp: 4.249 ± 1.409
2.704PheGlu: 2.704 ± 3.355
3.09PhePhe: 3.09 ± 4.13
3.09PheGly: 3.09 ± 1.142
1.931PheHis: 1.931 ± 0.603
2.704PheIle: 2.704 ± 1.947
0.772PheLys: 0.772 ± 1.589
6.566PheLeu: 6.566 ± 1.136
1.159PheMet: 1.159 ± 1.145
2.317PheAsn: 2.317 ± 0.876
5.794PhePro: 5.794 ± 1.73
1.159PheGln: 1.159 ± 0.97
2.704PheArg: 2.704 ± 1.049
2.317PheSer: 2.317 ± 0.655
3.09PheThr: 3.09 ± 1.284
3.09PheVal: 3.09 ± 1.168
0.772PheTrp: 0.772 ± 1.032
0.386PheTyr: 0.386 ± 0.181
0.0PheXaa: 0.0 ± 0.0
Gly
4.635GlyAla: 4.635 ± 1.31
0.386GlyCys: 0.386 ± 0.181
4.249GlyAsp: 4.249 ± 1.911
0.0GlyGlu: 0.0 ± 0.0
3.862GlyPhe: 3.862 ± 1.162
5.021GlyGly: 5.021 ± 1.513
1.931GlyHis: 1.931 ± 0.653
0.772GlyIle: 0.772 ± 0.362
2.704GlyLys: 2.704 ± 1.268
7.339GlyLeu: 7.339 ± 1.684
0.386GlyMet: 0.386 ± 0.181
1.545GlyAsn: 1.545 ± 0.725
2.704GlyPro: 2.704 ± 1.268
1.931GlyGln: 1.931 ± 0.603
3.476GlyArg: 3.476 ± 0.684
3.862GlySer: 3.862 ± 1.959
5.407GlyThr: 5.407 ± 1.678
5.407GlyVal: 5.407 ± 3.044
1.159GlyTrp: 1.159 ± 0.543
1.159GlyTyr: 1.159 ± 0.543
0.0GlyXaa: 0.0 ± 0.0
His
2.704HisAla: 2.704 ± 1.034
0.772HisCys: 0.772 ± 0.362
1.159HisAsp: 1.159 ± 0.543
0.772HisGlu: 0.772 ± 0.702
4.249HisPhe: 4.249 ± 1.798
1.159HisGly: 1.159 ± 0.543
1.545HisHis: 1.545 ± 0.725
1.545HisIle: 1.545 ± 1.801
0.386HisLys: 0.386 ± 1.091
3.862HisLeu: 3.862 ± 1.305
1.159HisMet: 1.159 ± 0.543
0.0HisAsn: 0.0 ± 0.0
1.159HisPro: 1.159 ± 0.543
2.317HisGln: 2.317 ± 1.74
3.09HisArg: 3.09 ± 0.987
3.09HisSer: 3.09 ± 1.502
2.704HisThr: 2.704 ± 1.268
1.545HisVal: 1.545 ± 0.699
0.772HisTrp: 0.772 ± 0.362
1.545HisTyr: 1.545 ± 0.725
0.0HisXaa: 0.0 ± 0.0
Ile
2.317IleAla: 2.317 ± 2.09
0.0IleCys: 0.0 ± 0.0
1.159IleAsp: 1.159 ± 0.543
1.159IleGlu: 1.159 ± 0.785
1.159IlePhe: 1.159 ± 0.97
3.476IleGly: 3.476 ± 1.682
0.386IleHis: 0.386 ± 0.181
0.772IleIle: 0.772 ± 0.9
1.545IleLys: 1.545 ± 0.584
2.317IleLeu: 2.317 ± 0.655
0.772IleMet: 0.772 ± 0.362
1.545IleAsn: 1.545 ± 1.242
3.476IlePro: 3.476 ± 1.892
1.159IleGln: 1.159 ± 1.931
1.931IleArg: 1.931 ± 1.247
3.862IleSer: 3.862 ± 2.62
1.931IleThr: 1.931 ± 0.653
2.317IleVal: 2.317 ± 1.087
0.0IleTrp: 0.0 ± 0.0
1.159IleTyr: 1.159 ± 0.543
0.0IleXaa: 0.0 ± 0.0
Lys
0.772LysAla: 0.772 ± 1.739
0.0LysCys: 0.0 ± 0.0
1.159LysAsp: 1.159 ± 0.62
0.772LysGlu: 0.772 ± 0.362
0.772LysPhe: 0.772 ± 0.362
1.545LysGly: 1.545 ± 0.699
1.545LysHis: 1.545 ± 2.469
0.386LysIle: 0.386 ± 0.816
1.159LysLys: 1.159 ± 0.543
5.021LysLeu: 5.021 ± 1.244
0.772LysMet: 0.772 ± 0.362
0.386LysAsn: 0.386 ± 0.181
1.159LysPro: 1.159 ± 0.543
1.159LysGln: 1.159 ± 0.62
3.09LysArg: 3.09 ± 2.553
0.772LysSer: 0.772 ± 0.362
1.545LysThr: 1.545 ± 0.725
2.317LysVal: 2.317 ± 0.981
3.09LysTrp: 3.09 ± 1.449
0.386LysTyr: 0.386 ± 1.091
0.0LysXaa: 0.0 ± 0.0
Leu
6.952LeuAla: 6.952 ± 0.954
0.772LeuCys: 0.772 ± 0.362
6.566LeuAsp: 6.566 ± 0.873
1.545LeuGlu: 1.545 ± 0.725
4.249LeuPhe: 4.249 ± 1.031
6.18LeuGly: 6.18 ± 1.658
3.862LeuHis: 3.862 ± 0.991
3.09LeuIle: 3.09 ± 3.722
4.635LeuLys: 4.635 ± 2.027
8.111LeuLeu: 8.111 ± 2.357
2.317LeuMet: 2.317 ± 0.673
2.317LeuAsn: 2.317 ± 1.087
11.201LeuPro: 11.201 ± 1.187
3.09LeuGln: 3.09 ± 1.449
5.407LeuArg: 5.407 ± 1.336
9.27LeuSer: 9.27 ± 2.925
12.36LeuThr: 12.36 ± 2.78
8.111LeuVal: 8.111 ± 3.466
1.545LeuTrp: 1.545 ± 0.94
4.635LeuTyr: 4.635 ± 1.537
0.0LeuXaa: 0.0 ± 0.0
Met
1.545MetAla: 1.545 ± 0.584
0.386MetCys: 0.386 ± 0.181
0.386MetAsp: 0.386 ± 0.181
0.386MetGlu: 0.386 ± 0.181
0.0MetPhe: 0.0 ± 0.0
0.772MetGly: 0.772 ± 0.362
0.772MetHis: 0.772 ± 0.362
0.772MetIle: 0.772 ± 0.362
0.772MetLys: 0.772 ± 0.362
1.545MetLeu: 1.545 ± 1.242
0.0MetMet: 0.0 ± 0.0
1.159MetAsn: 1.159 ± 0.543
1.545MetPro: 1.545 ± 0.725
0.386MetGln: 0.386 ± 0.181
0.772MetArg: 0.772 ± 0.362
1.545MetSer: 1.545 ± 0.699
0.772MetThr: 0.772 ± 1.589
0.772MetVal: 0.772 ± 0.702
0.386MetTrp: 0.386 ± 0.181
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
1.931AsnAla: 1.931 ± 1.206
0.772AsnCys: 0.772 ± 0.362
1.931AsnAsp: 1.931 ± 0.906
1.159AsnGlu: 1.159 ± 0.543
3.476AsnPhe: 3.476 ± 1.912
0.772AsnGly: 0.772 ± 0.987
0.772AsnHis: 0.772 ± 0.362
0.386AsnIle: 0.386 ± 0.181
0.0AsnLys: 0.0 ± 0.0
3.09AsnLeu: 3.09 ± 0.795
0.386AsnMet: 0.386 ± 0.181
0.386AsnAsn: 0.386 ± 0.181
1.931AsnPro: 1.931 ± 0.603
0.772AsnGln: 0.772 ± 0.987
1.159AsnArg: 1.159 ± 0.543
1.545AsnSer: 1.545 ± 0.725
1.545AsnThr: 1.545 ± 0.725
1.159AsnVal: 1.159 ± 0.543
0.772AsnTrp: 0.772 ± 0.362
1.931AsnTyr: 1.931 ± 0.906
0.0AsnXaa: 0.0 ± 0.0
Pro
10.429ProAla: 10.429 ± 2.486
0.0ProCys: 0.0 ± 0.0
4.249ProAsp: 4.249 ± 1.195
2.704ProGlu: 2.704 ± 2.239
5.021ProPhe: 5.021 ± 0.706
5.407ProGly: 5.407 ± 1.343
3.476ProHis: 3.476 ± 1.63
1.159ProIle: 1.159 ± 1.369
4.249ProLys: 4.249 ± 0.721
9.27ProLeu: 9.27 ± 0.628
0.772ProMet: 0.772 ± 0.362
2.317ProAsn: 2.317 ± 1.087
9.656ProPro: 9.656 ± 3.913
2.704ProGln: 2.704 ± 1.585
4.635ProArg: 4.635 ± 1.666
8.884ProSer: 8.884 ± 2.785
7.725ProThr: 7.725 ± 3.722
6.952ProVal: 6.952 ± 1.949
0.386ProTrp: 0.386 ± 0.181
2.317ProTyr: 2.317 ± 1.087
0.0ProXaa: 0.0 ± 0.0
Gln
2.704GlnAla: 2.704 ± 0.938
0.0GlnCys: 0.0 ± 0.0
0.772GlnAsp: 0.772 ± 0.362
0.772GlnGlu: 0.772 ± 0.362
0.772GlnPhe: 0.772 ± 1.032
2.317GlnGly: 2.317 ± 0.673
0.772GlnHis: 0.772 ± 0.362
0.386GlnIle: 0.386 ± 0.181
1.159GlnLys: 1.159 ± 1.45
4.249GlnLeu: 4.249 ± 3.867
0.0GlnMet: 0.0 ± 0.0
0.772GlnAsn: 0.772 ± 0.362
2.317GlnPro: 2.317 ± 1.239
2.317GlnGln: 2.317 ± 1.038
3.476GlnArg: 3.476 ± 1.63
2.317GlnSer: 2.317 ± 0.673
1.931GlnThr: 1.931 ± 0.653
3.476GlnVal: 3.476 ± 1.174
0.0GlnTrp: 0.0 ± 0.0
0.772GlnTyr: 0.772 ± 0.362
0.0GlnXaa: 0.0 ± 0.0
Arg
8.497ArgAla: 8.497 ± 0.668
0.772ArgCys: 0.772 ± 0.362
2.704ArgAsp: 2.704 ± 1.024
1.545ArgGlu: 1.545 ± 0.725
3.862ArgPhe: 3.862 ± 1.886
2.317ArgGly: 2.317 ± 1.087
1.931ArgHis: 1.931 ± 0.906
3.09ArgIle: 3.09 ± 0.795
1.159ArgLys: 1.159 ± 0.908
6.952ArgLeu: 6.952 ± 0.912
0.386ArgMet: 0.386 ± 0.186
2.317ArgAsn: 2.317 ± 1.087
3.09ArgPro: 3.09 ± 0.935
1.159ArgGln: 1.159 ± 0.908
3.476ArgArg: 3.476 ± 1.055
3.09ArgSer: 3.09 ± 0.946
6.566ArgThr: 6.566 ± 2.468
4.635ArgVal: 4.635 ± 1.546
1.545ArgTrp: 1.545 ± 0.725
1.931ArgTyr: 1.931 ± 0.849
0.0ArgXaa: 0.0 ± 0.0
Ser
9.656SerAla: 9.656 ± 2.277
0.386SerCys: 0.386 ± 1.121
3.862SerAsp: 3.862 ± 0.893
1.545SerGlu: 1.545 ± 1.219
2.317SerPhe: 2.317 ± 1.239
5.407SerGly: 5.407 ± 3.063
2.704SerHis: 2.704 ± 0.705
2.704SerIle: 2.704 ± 1.947
2.704SerLys: 2.704 ± 1.049
8.884SerLeu: 8.884 ± 1.288
0.0SerMet: 0.0 ± 0.0
1.159SerAsn: 1.159 ± 0.62
9.656SerPro: 9.656 ± 2.118
1.931SerGln: 1.931 ± 0.906
6.952SerArg: 6.952 ± 1.721
6.566SerSer: 6.566 ± 5.699
2.704SerThr: 2.704 ± 2.047
2.704SerVal: 2.704 ± 1.024
1.545SerTrp: 1.545 ± 0.725
1.931SerTyr: 1.931 ± 0.943
0.0SerXaa: 0.0 ± 0.0
Thr
6.18ThrAla: 6.18 ± 1.423
1.159ThrCys: 1.159 ± 0.97
5.021ThrAsp: 5.021 ± 0.884
1.545ThrGlu: 1.545 ± 0.699
3.476ThrPhe: 3.476 ± 0.684
4.635ThrGly: 4.635 ± 1.537
3.09ThrHis: 3.09 ± 1.142
1.931ThrIle: 1.931 ± 1.68
1.159ThrLys: 1.159 ± 0.785
7.725ThrLeu: 7.725 ± 2.545
2.317ThrMet: 2.317 ± 0.673
1.159ThrAsn: 1.159 ± 0.543
10.042ThrPro: 10.042 ± 1.945
1.545ThrGln: 1.545 ± 0.725
4.249ThrArg: 4.249 ± 1.031
5.794ThrSer: 5.794 ± 1.286
3.862ThrThr: 3.862 ± 1.048
6.18ThrVal: 6.18 ± 1.943
2.317ThrTrp: 2.317 ± 0.655
3.09ThrTyr: 3.09 ± 0.946
0.0ThrXaa: 0.0 ± 0.0
Val
6.18ValAla: 6.18 ± 1.341
1.931ValCys: 1.931 ± 0.906
3.862ValAsp: 3.862 ± 1.21
1.545ValGlu: 1.545 ± 0.86
3.862ValPhe: 3.862 ± 1.666
3.862ValGly: 3.862 ± 1.048
3.476ValHis: 3.476 ± 0.972
3.862ValIle: 3.862 ± 0.996
0.772ValLys: 0.772 ± 0.9
6.18ValLeu: 6.18 ± 1.733
0.386ValMet: 0.386 ± 0.765
1.931ValAsn: 1.931 ± 0.906
8.884ValPro: 8.884 ± 3.019
2.704ValGln: 2.704 ± 0.971
5.407ValArg: 5.407 ± 1.693
6.566ValSer: 6.566 ± 2.536
3.862ValThr: 3.862 ± 1.381
3.862ValVal: 3.862 ± 1.21
2.704ValTrp: 2.704 ± 1.268
2.704ValTyr: 2.704 ± 1.191
0.0ValXaa: 0.0 ± 0.0
Trp
1.931TrpAla: 1.931 ± 0.943
0.386TrpCys: 0.386 ± 0.181
1.931TrpAsp: 1.931 ± 0.906
0.0TrpGlu: 0.0 ± 0.0
1.545TrpPhe: 1.545 ± 0.725
0.386TrpGly: 0.386 ± 0.181
0.0TrpHis: 0.0 ± 0.0
0.386TrpIle: 0.386 ± 0.181
0.0TrpLys: 0.0 ± 0.0
5.021TrpLeu: 5.021 ± 1.732
0.386TrpMet: 0.386 ± 0.713
1.159TrpAsn: 1.159 ± 0.97
1.159TrpPro: 1.159 ± 0.543
1.545TrpGln: 1.545 ± 0.725
1.931TrpArg: 1.931 ± 0.906
1.931TrpSer: 1.931 ± 0.943
1.545TrpThr: 1.545 ± 0.725
1.545TrpVal: 1.545 ± 0.725
0.772TrpTrp: 0.772 ± 0.362
0.772TrpTyr: 0.772 ± 0.362
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.862TyrAla: 3.862 ± 1.811
0.772TyrCys: 0.772 ± 0.702
0.772TyrAsp: 0.772 ± 0.9
0.772TyrGlu: 0.772 ± 0.362
1.545TyrPhe: 1.545 ± 2.469
3.09TyrGly: 3.09 ± 1.449
1.931TyrHis: 1.931 ± 1.073
2.317TyrIle: 2.317 ± 1.087
0.386TyrLys: 0.386 ± 0.181
3.476TyrLeu: 3.476 ± 1.141
0.0TyrMet: 0.0 ± 0.0
1.159TyrAsn: 1.159 ± 0.908
0.772TyrPro: 0.772 ± 0.362
1.159TyrGln: 1.159 ± 0.543
0.386TyrArg: 0.386 ± 0.181
1.545TyrSer: 1.545 ± 0.725
4.249TyrThr: 4.249 ± 1.916
1.545TyrVal: 1.545 ± 0.699
1.159TyrTrp: 1.159 ± 0.543
0.386TyrTyr: 0.386 ± 0.181
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (2590 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski