Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) (Dandruff-associated fungus)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Fungi; Dikarya; Basidiomycota; Ustilaginomycotina; Malasseziomycetes; Malasseziales; Malasseziaceae; Malassezia; Malassezia globosa

Average proteome isoelectric point is 6.53

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 4274 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A8PY24|A8PY24_MALGO Glutaredoxin-like protein OS=Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) OX=425265 GN=MGL_1576 PE=3 SV=1
MM1 pKa = 8.07DD2 pKa = 6.04LLDD5 pKa = 5.4AEE7 pKa = 4.45QQEE10 pKa = 4.74ALPFSLDD17 pKa = 3.64YY18 pKa = 10.67YY19 pKa = 11.12TDD21 pKa = 3.92AQDD24 pKa = 3.8LNYY27 pKa = 9.81MADD30 pKa = 4.01YY31 pKa = 10.9LHH33 pKa = 6.26EE34 pKa = 4.39TQPRR38 pKa = 11.84VARR41 pKa = 11.84MYY43 pKa = 10.4EE44 pKa = 3.83VLGDD48 pKa = 3.73IVQEE52 pKa = 3.94YY53 pKa = 10.44GLVSFEE59 pKa = 4.05TLAVEE64 pKa = 5.23EE65 pKa = 4.41KK66 pKa = 11.02ASMLHH71 pKa = 5.84LVEE74 pKa = 4.24VLDD77 pKa = 3.94RR78 pKa = 11.84AIGYY82 pKa = 7.27VARR85 pKa = 11.84DD86 pKa = 3.47SAA88 pKa = 4.09

Molecular weight: 10.06 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A8Q258|A8Q258_MALGO Uncharacterized protein OS=Malassezia globosa (strain ATCC MYA-4612 / CBS 7966) OX=425265 GN=MGL_2143 PE=3 SV=1
MM1 pKa = 7.42MFQPSAVCKK10 pKa = 9.64TVVPDD15 pKa = 3.46TFRR18 pKa = 11.84VLRR21 pKa = 11.84SQRR24 pKa = 11.84RR25 pKa = 11.84RR26 pKa = 11.84WINSTVHH33 pKa = 6.36NLFEE37 pKa = 5.35LIQVRR42 pKa = 11.84DD43 pKa = 3.64LCGTFCFSMRR53 pKa = 11.84FVVFMDD59 pKa = 3.76LVGTMVLPAAIAFTVFVVVQAILTPFQNKK88 pKa = 9.68GKK90 pKa = 10.22DD91 pKa = 3.37DD92 pKa = 4.04GEE94 pKa = 4.2KK95 pKa = 10.58KK96 pKa = 10.08EE97 pKa = 4.35FPTMPLVLLALILGLPGVLIVITSRR122 pKa = 11.84RR123 pKa = 11.84FMYY126 pKa = 8.67VIWMLVYY133 pKa = 10.76LISLPIWNLILPAYY147 pKa = 9.65SYY149 pKa = 9.94WHH151 pKa = 6.69MDD153 pKa = 3.41DD154 pKa = 4.78FSWGATRR161 pKa = 11.84MVQGEE166 pKa = 4.5KK167 pKa = 10.14KK168 pKa = 10.62GEE170 pKa = 4.09SHH172 pKa = 6.85GSAEE176 pKa = 4.37GEE178 pKa = 3.85FDD180 pKa = 4.24ASDD183 pKa = 3.15IVMKK187 pKa = 10.49RR188 pKa = 11.84YY189 pKa = 9.89VEE191 pKa = 4.14YY192 pKa = 10.47EE193 pKa = 3.56RR194 pKa = 11.84EE195 pKa = 4.05RR196 pKa = 11.84RR197 pKa = 11.84WRR199 pKa = 11.84SGMEE203 pKa = 3.87SRR205 pKa = 11.84DD206 pKa = 3.69APSEE210 pKa = 4.15SGGMSTLGSLNEE222 pKa = 4.25EE223 pKa = 4.38KK224 pKa = 10.76ALPPPGADD232 pKa = 2.82EE233 pKa = 3.98RR234 pKa = 11.84SARR237 pKa = 11.84HH238 pKa = 5.91RR239 pKa = 11.84LDD241 pKa = 3.39SVPLLEE247 pKa = 5.34LPAPLGSDD255 pKa = 2.92SRR257 pKa = 11.84QRR259 pKa = 11.84AGTMSPPVPGGKK271 pKa = 9.92GPNGARR277 pKa = 11.84SSPAGTTSPPNPWTSSGALTQTGPAPLTAQRR308 pKa = 11.84VNPSPNPSASAMARR322 pKa = 11.84QHH324 pKa = 6.61LFGATPTSAAHH335 pKa = 6.62ASMPVRR341 pKa = 11.84PPGTISPPPRR351 pKa = 11.84PSNIGASGPVSPPSFRR367 pKa = 11.84GNVSPPPMFPAGPLSPVNTRR387 pKa = 11.84PTPPVRR393 pKa = 11.84PVAPSPSGWNAASQPARR410 pKa = 11.84PANTQAYY417 pKa = 7.09PSPPSSGTQPGSAPTLAGFQPLSPPSASRR446 pKa = 11.84PPPLRR451 pKa = 11.84APSNAQQMRR460 pKa = 11.84GDD462 pKa = 3.59VRR464 pKa = 11.84RR465 pKa = 11.84VSLVDD470 pKa = 4.24DD471 pKa = 4.79GPVATSGGSMRR482 pKa = 11.84QVVRR486 pKa = 11.84GARR489 pKa = 11.84RR490 pKa = 11.84QSSINSGAPNSASTASPPSNSNPFSRR516 pKa = 11.84PANPFSPPPKK526 pKa = 10.17

Molecular weight: 56.07 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

4273

1

4274

2064385

14

4917

483.0

53.48

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

9.527 ± 0.046

1.292 ± 0.012

5.843 ± 0.024

5.865 ± 0.034

3.245 ± 0.024

5.839 ± 0.033

3.16 ± 0.02

4.037 ± 0.026

3.877 ± 0.033

9.45 ± 0.049

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.727 ± 0.013

3.037 ± 0.023

6.123 ± 0.045

4.27 ± 0.022

6.743 ± 0.032

8.674 ± 0.05

5.871 ± 0.023

6.526 ± 0.029

1.339 ± 0.013

2.553 ± 0.017
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski