Amino acid dipepetide frequency for Drechslerella stenobrocha 248

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.059AlaAla: 10.059 ± 0.093	0.981AlaCys: 0.981 ± 0.023	4.477AlaAsp: 4.477 ± 0.041	5.326AlaGlu: 5.326 ± 0.056	2.914AlaPhe: 2.914 ± 0.039	6.192AlaGly: 6.192 ± 0.057	1.703AlaHis: 1.703 ± 0.025	4.335AlaIle: 4.335 ± 0.045	4.244AlaLys: 4.244 ± 0.045	7.374AlaLeu: 7.374 ± 0.065	1.831AlaMet: 1.831 ± 0.025	3.01AlaAsn: 3.01 ± 0.034	5.238AlaPro: 5.238 ± 0.057	3.321AlaGln: 3.321 ± 0.046	4.967AlaArg: 4.967 ± 0.05	7.33AlaSer: 7.33 ± 0.059	5.673AlaThr: 5.673 ± 0.053	5.634AlaVal: 5.634 ± 0.052	0.981AlaTrp: 0.981 ± 0.019	2.112AlaTyr: 2.112 ± 0.026	0.0AlaXaa: 0.0 ± 0.0
Cys	0.858CysAla: 0.858 ± 0.018	0.22CysCys: 0.22 ± 0.01	0.635CysAsp: 0.635 ± 0.013	0.573CysGlu: 0.573 ± 0.018	0.487CysPhe: 0.487 ± 0.015	0.913CysGly: 0.913 ± 0.021	0.282CysHis: 0.282 ± 0.01	0.661CysIle: 0.661 ± 0.018	0.523CysLys: 0.523 ± 0.013	1.135CysLeu: 1.135 ± 0.025	0.252CysMet: 0.252 ± 0.009	0.425CysAsn: 0.425 ± 0.013	0.61CysPro: 0.61 ± 0.018	0.383CysGln: 0.383 ± 0.012	0.736CysArg: 0.736 ± 0.02	0.817CysSer: 0.817 ± 0.019	0.632CysThr: 0.632 ± 0.016	0.723CysVal: 0.723 ± 0.015	0.167CysTrp: 0.167 ± 0.007	0.343CysTyr: 0.343 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	4.87AspAla: 4.87 ± 0.048	0.607AspCys: 0.607 ± 0.015	5.006AspAsp: 5.006 ± 0.091	4.731AspGlu: 4.731 ± 0.06	2.129AspPhe: 2.129 ± 0.033	4.399AspGly: 4.399 ± 0.044	1.178AspHis: 1.178 ± 0.023	3.271AspIle: 3.271 ± 0.039	2.497AspLys: 2.497 ± 0.032	4.893AspLeu: 4.893 ± 0.044	1.273AspMet: 1.273 ± 0.027	1.973AspAsn: 1.973 ± 0.027	3.306AspPro: 3.306 ± 0.038	1.712AspGln: 1.712 ± 0.025	3.106AspArg: 3.106 ± 0.042	4.219AspSer: 4.219 ± 0.038	3.017AspThr: 3.017 ± 0.035	3.571AspVal: 3.571 ± 0.038	0.835AspTrp: 0.835 ± 0.017	1.647AspTyr: 1.647 ± 0.023	0.0AspXaa: 0.0 ± 0.0
Glu	5.404GluAla: 5.404 ± 0.058	0.607GluCys: 0.607 ± 0.015	4.439GluAsp: 4.439 ± 0.058	5.862GluGlu: 5.862 ± 0.079	2.066GluPhe: 2.066 ± 0.028	3.978GluGly: 3.978 ± 0.054	1.307GluHis: 1.307 ± 0.023	3.148GluIle: 3.148 ± 0.034	3.788GluLys: 3.788 ± 0.051	5.307GluLeu: 5.307 ± 0.059	1.504GluMet: 1.504 ± 0.026	2.316GluAsn: 2.316 ± 0.029	2.883GluPro: 2.883 ± 0.042	2.432GluGln: 2.432 ± 0.031	4.126GluArg: 4.126 ± 0.056	4.146GluSer: 4.146 ± 0.042	3.418GluThr: 3.418 ± 0.04	3.667GluVal: 3.667 ± 0.047	0.816GluTrp: 0.816 ± 0.017	1.747GluTyr: 1.747 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	2.888PheAla: 2.888 ± 0.034	0.526PheCys: 0.526 ± 0.014	2.222PheAsp: 2.222 ± 0.029	2.213PheGlu: 2.213 ± 0.028	1.462PhePhe: 1.462 ± 0.029	2.733PheGly: 2.733 ± 0.044	0.819PheHis: 0.819 ± 0.019	1.681PheIle: 1.681 ± 0.026	1.626PheLys: 1.626 ± 0.027	3.203PheLeu: 3.203 ± 0.041	0.73PheMet: 0.73 ± 0.014	1.42PheAsn: 1.42 ± 0.022	1.86PhePro: 1.86 ± 0.03	1.351PheGln: 1.351 ± 0.022	1.924PheArg: 1.924 ± 0.024	2.856PheSer: 2.856 ± 0.038	2.116PheThr: 2.116 ± 0.028	2.261PheVal: 2.261 ± 0.035	0.554PheTrp: 0.554 ± 0.017	1.066PheTyr: 1.066 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	5.53GlyAla: 5.53 ± 0.053	0.843GlyCys: 0.843 ± 0.016	3.872GlyAsp: 3.872 ± 0.04	3.922GlyGlu: 3.922 ± 0.05	2.728GlyPhe: 2.728 ± 0.038	6.632GlyGly: 6.632 ± 0.092	1.559GlyHis: 1.559 ± 0.027	3.439GlyIle: 3.439 ± 0.039	3.668GlyLys: 3.668 ± 0.044	5.725GlyLeu: 5.725 ± 0.053	1.564GlyMet: 1.564 ± 0.028	2.719GlyAsn: 2.719 ± 0.049	3.28GlyPro: 3.28 ± 0.043	2.42GlyGln: 2.42 ± 0.034	4.182GlyArg: 4.182 ± 0.043	5.833GlySer: 5.833 ± 0.062	3.921GlyThr: 3.921 ± 0.042	4.5GlyVal: 4.5 ± 0.043	1.068GlyTrp: 1.068 ± 0.02	2.125GlyTyr: 2.125 ± 0.033	0.0GlyXaa: 0.0 ± 0.0
His	1.758HisAla: 1.758 ± 0.027	0.294HisCys: 0.294 ± 0.012	1.182HisAsp: 1.182 ± 0.021	1.229HisGlu: 1.229 ± 0.024	0.826HisPhe: 0.826 ± 0.018	1.548HisGly: 1.548 ± 0.029	0.917HisHis: 0.917 ± 0.027	1.157HisIle: 1.157 ± 0.022	0.926HisLys: 0.926 ± 0.017	2.101HisLeu: 2.101 ± 0.029	0.469HisMet: 0.469 ± 0.012	0.824HisAsn: 0.824 ± 0.018	1.653HisPro: 1.653 ± 0.026	0.996HisGln: 0.996 ± 0.023	1.527HisArg: 1.527 ± 0.025	1.802HisSer: 1.802 ± 0.03	1.196HisThr: 1.196 ± 0.024	1.296HisVal: 1.296 ± 0.029	0.263HisTrp: 0.263 ± 0.01	0.655HisTyr: 0.655 ± 0.014	0.0HisXaa: 0.0 ± 0.0
Ile	4.243IleAla: 4.243 ± 0.041	0.714IleCys: 0.714 ± 0.017	2.952IleAsp: 2.952 ± 0.037	2.911IleGlu: 2.911 ± 0.03	1.839IlePhe: 1.839 ± 0.03	3.128IleGly: 3.128 ± 0.035	1.149IleHis: 1.149 ± 0.023	2.421IleIle: 2.421 ± 0.032	2.373IleLys: 2.373 ± 0.029	4.372IleLeu: 4.372 ± 0.054	0.972IleMet: 0.972 ± 0.02	1.817IleAsn: 1.817 ± 0.027	3.125IlePro: 3.125 ± 0.036	1.86IleGln: 1.86 ± 0.029	2.837IleArg: 2.837 ± 0.033	3.931IleSer: 3.931 ± 0.04	2.934IleThr: 2.934 ± 0.033	3.21IleVal: 3.21 ± 0.036	0.655IleTrp: 0.655 ± 0.016	1.415IleTyr: 1.415 ± 0.023	0.0IleXaa: 0.0 ± 0.0
Lys	4.496LysAla: 4.496 ± 0.049	0.513LysCys: 0.513 ± 0.014	2.89LysAsp: 2.89 ± 0.036	3.577LysGlu: 3.577 ± 0.045	1.565LysPhe: 1.565 ± 0.024	3.121LysGly: 3.121 ± 0.041	1.09LysHis: 1.09 ± 0.022	2.408LysIle: 2.408 ± 0.032	3.757LysLys: 3.757 ± 0.079	4.403LysLeu: 4.403 ± 0.041	1.047LysMet: 1.047 ± 0.019	1.808LysAsn: 1.808 ± 0.025	2.954LysPro: 2.954 ± 0.043	1.879LysGln: 1.879 ± 0.031	3.656LysArg: 3.656 ± 0.042	3.61LysSer: 3.61 ± 0.043	2.915LysThr: 2.915 ± 0.035	2.995LysVal: 2.995 ± 0.032	0.635LysTrp: 0.635 ± 0.017	1.428LysTyr: 1.428 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	7.712LeuAla: 7.712 ± 0.053	1.085LeuCys: 1.085 ± 0.022	5.109LeuAsp: 5.109 ± 0.054	5.606LeuGlu: 5.606 ± 0.054	3.089LeuPhe: 3.089 ± 0.038	5.429LeuGly: 5.429 ± 0.048	2.075LeuHis: 2.075 ± 0.027	3.681LeuIle: 3.681 ± 0.044	4.504LeuLys: 4.504 ± 0.049	8.175LeuLeu: 8.175 ± 0.082	1.727LeuMet: 1.727 ± 0.025	3.087LeuAsn: 3.087 ± 0.038	5.509LeuPro: 5.509 ± 0.05	3.809LeuGln: 3.809 ± 0.044	5.539LeuArg: 5.539 ± 0.053	6.967LeuSer: 6.967 ± 0.062	4.733LeuThr: 4.733 ± 0.041	5.309LeuVal: 5.309 ± 0.052	1.038LeuTrp: 1.038 ± 0.021	2.249LeuTyr: 2.249 ± 0.032	0.0LeuXaa: 0.0 ± 0.0
Met	2.106MetAla: 2.106 ± 0.025	0.213MetCys: 0.213 ± 0.009	1.27MetAsp: 1.27 ± 0.023	1.329MetGlu: 1.329 ± 0.024	0.746MetPhe: 0.746 ± 0.017	1.384MetGly: 1.384 ± 0.022	0.478MetHis: 0.478 ± 0.021	0.926MetIle: 0.926 ± 0.018	1.076MetLys: 1.076 ± 0.019	1.816MetLeu: 1.816 ± 0.027	0.593MetMet: 0.593 ± 0.016	0.766MetAsn: 0.766 ± 0.019	1.259MetPro: 1.259 ± 0.022	0.844MetGln: 0.844 ± 0.018	1.265MetArg: 1.265 ± 0.023	1.784MetSer: 1.784 ± 0.025	1.161MetThr: 1.161 ± 0.022	1.299MetVal: 1.299 ± 0.023	0.245MetTrp: 0.245 ± 0.009	0.51MetTyr: 0.51 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.995AsnAla: 2.995 ± 0.033	0.464AsnCys: 0.464 ± 0.014	1.872AsnAsp: 1.872 ± 0.028	1.938AsnGlu: 1.938 ± 0.027	1.412AsnPhe: 1.412 ± 0.022	3.068AsnGly: 3.068 ± 0.05	0.833AsnHis: 0.833 ± 0.018	2.094AsnIle: 2.094 ± 0.03	1.573AsnLys: 1.573 ± 0.028	3.307AsnLeu: 3.307 ± 0.038	0.848AsnMet: 0.848 ± 0.02	1.544AsnAsn: 1.544 ± 0.03	2.615AsnPro: 2.615 ± 0.029	1.349AsnGln: 1.349 ± 0.023	2.063AsnArg: 2.063 ± 0.029	2.848AsnSer: 2.848 ± 0.034	2.213AsnThr: 2.213 ± 0.036	2.286AsnVal: 2.286 ± 0.029	0.509AsnTrp: 0.509 ± 0.013	1.067AsnTyr: 1.067 ± 0.022	0.0AsnXaa: 0.0 ± 0.0
Pro	5.896ProAla: 5.896 ± 0.064	0.44ProCys: 0.44 ± 0.012	3.232ProAsp: 3.232 ± 0.032	3.677ProGlu: 3.677 ± 0.043	1.958ProPhe: 1.958 ± 0.028	4.039ProGly: 4.039 ± 0.048	1.319ProHis: 1.319 ± 0.028	2.652ProIle: 2.652 ± 0.033	2.846ProLys: 2.846 ± 0.043	4.664ProLeu: 4.664 ± 0.049	1.079ProMet: 1.079 ± 0.021	2.193ProAsn: 2.193 ± 0.035	6.263ProPro: 6.263 ± 0.111	2.664ProGln: 2.664 ± 0.047	3.441ProArg: 3.441 ± 0.037	6.141ProSer: 6.141 ± 0.064	4.453ProThr: 4.453 ± 0.056	3.82ProVal: 3.82 ± 0.044	0.629ProTrp: 0.629 ± 0.015	1.504ProTyr: 1.504 ± 0.024	0.0ProXaa: 0.0 ± 0.0
Gln	3.325GlnAla: 3.325 ± 0.04	0.386GlnCys: 0.386 ± 0.012	1.972GlnAsp: 1.972 ± 0.026	2.338GlnGlu: 2.338 ± 0.035	1.246GlnPhe: 1.246 ± 0.021	2.21GlnGly: 2.21 ± 0.03	1.029GlnHis: 1.029 ± 0.021	1.856GlnIle: 1.856 ± 0.026	2.053GlnLys: 2.053 ± 0.027	3.447GlnLeu: 3.447 ± 0.04	0.889GlnMet: 0.889 ± 0.02	1.544GlnAsn: 1.544 ± 0.027	2.678GlnPro: 2.678 ± 0.045	2.833GlnGln: 2.833 ± 0.1	2.612GlnArg: 2.612 ± 0.034	2.996GlnSer: 2.996 ± 0.039	2.304GlnThr: 2.304 ± 0.029	2.109GlnVal: 2.109 ± 0.026	0.475GlnTrp: 0.475 ± 0.014	1.116GlnTyr: 1.116 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	4.723ArgAla: 4.723 ± 0.047	0.658ArgCys: 0.658 ± 0.015	3.405ArgAsp: 3.405 ± 0.04	4.05ArgGlu: 4.05 ± 0.056	2.101ArgPhe: 2.101 ± 0.029	3.862ArgGly: 3.862 ± 0.043	1.518ArgHis: 1.518 ± 0.024	2.904ArgIle: 2.904 ± 0.034	3.737ArgLys: 3.737 ± 0.044	5.381ArgLeu: 5.381 ± 0.049	1.369ArgMet: 1.369 ± 0.021	2.303ArgAsn: 2.303 ± 0.032	3.516ArgPro: 3.516 ± 0.043	2.631ArgGln: 2.631 ± 0.036	5.285ArgArg: 5.285 ± 0.061	4.696ArgSer: 4.696 ± 0.048	3.328ArgThr: 3.328 ± 0.03	3.422ArgVal: 3.422 ± 0.042	0.84ArgTrp: 0.84 ± 0.02	1.715ArgTyr: 1.715 ± 0.026	0.0ArgXaa: 0.0 ± 0.0
Ser	6.721SerAla: 6.721 ± 0.06	0.805SerCys: 0.805 ± 0.017	4.323SerAsp: 4.323 ± 0.045	4.077SerGlu: 4.077 ± 0.046	2.828SerPhe: 2.828 ± 0.031	5.701SerGly: 5.701 ± 0.056	1.822SerHis: 1.822 ± 0.031	3.975SerIle: 3.975 ± 0.039	3.828SerLys: 3.828 ± 0.042	6.936SerLeu: 6.936 ± 0.058	1.61SerMet: 1.61 ± 0.026	3.006SerAsn: 3.006 ± 0.035	5.848SerPro: 5.848 ± 0.069	3.118SerGln: 3.118 ± 0.036	5.042SerArg: 5.042 ± 0.048	9.05SerSer: 9.05 ± 0.113	5.813SerThr: 5.813 ± 0.084	4.502SerVal: 4.502 ± 0.037	0.945SerTrp: 0.945 ± 0.02	2.026SerTyr: 2.026 ± 0.029	0.0SerXaa: 0.0 ± 0.0
Thr	5.678ThrAla: 5.678 ± 0.049	0.691ThrCys: 0.691 ± 0.018	2.966ThrAsp: 2.966 ± 0.035	3.151ThrGlu: 3.151 ± 0.041	2.135ThrPhe: 2.135 ± 0.029	4.28ThrGly: 4.28 ± 0.055	1.206ThrHis: 1.206 ± 0.022	3.19ThrIle: 3.19 ± 0.039	2.731ThrLys: 2.731 ± 0.033	5.019ThrLeu: 5.019 ± 0.043	1.111ThrMet: 1.111 ± 0.02	2.195ThrAsn: 2.195 ± 0.028	4.642ThrPro: 4.642 ± 0.062	1.97ThrGln: 1.97 ± 0.03	3.156ThrArg: 3.156 ± 0.034	5.499ThrSer: 5.499 ± 0.066	4.959ThrThr: 4.959 ± 0.096	3.941ThrVal: 3.941 ± 0.051	0.714ThrTrp: 0.714 ± 0.016	1.504ThrTyr: 1.504 ± 0.024	0.0ThrXaa: 0.0 ± 0.0
Val	5.426ValAla: 5.426 ± 0.055	0.758ValCys: 0.758 ± 0.018	3.798ValAsp: 3.798 ± 0.042	4.127ValGlu: 4.127 ± 0.05	2.334ValPhe: 2.334 ± 0.028	4.092ValGly: 4.092 ± 0.041	1.317ValHis: 1.317 ± 0.022	3.001ValIle: 3.001 ± 0.043	3.045ValLys: 3.045 ± 0.037	5.462ValLeu: 5.462 ± 0.053	1.297ValMet: 1.297 ± 0.026	2.225ValAsn: 2.225 ± 0.027	3.676ValPro: 3.676 ± 0.043	2.298ValGln: 2.298 ± 0.03	3.454ValArg: 3.454 ± 0.036	4.495ValSer: 4.495 ± 0.042	3.559ValThr: 3.559 ± 0.042	4.508ValVal: 4.508 ± 0.057	0.79ValTrp: 0.79 ± 0.017	1.777ValTyr: 1.777 ± 0.029	0.0ValXaa: 0.0 ± 0.0
Trp	0.952TrpAla: 0.952 ± 0.018	0.182TrpCys: 0.182 ± 0.008	0.869TrpAsp: 0.869 ± 0.02	0.807TrpGlu: 0.807 ± 0.017	0.489TrpPhe: 0.489 ± 0.014	0.854TrpGly: 0.854 ± 0.02	0.312TrpHis: 0.312 ± 0.011	0.601TrpIle: 0.601 ± 0.016	0.76TrpLys: 0.76 ± 0.018	1.118TrpLeu: 1.118 ± 0.019	0.34TrpMet: 0.34 ± 0.011	0.531TrpAsn: 0.531 ± 0.014	0.494TrpPro: 0.494 ± 0.013	0.477TrpGln: 0.477 ± 0.013	0.896TrpArg: 0.896 ± 0.02	0.898TrpSer: 0.898 ± 0.019	0.752TrpThr: 0.752 ± 0.016	0.817TrpVal: 0.817 ± 0.016	0.266TrpTrp: 0.266 ± 0.01	0.392TrpTyr: 0.392 ± 0.012	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.064TyrAla: 2.064 ± 0.022	0.387TyrCys: 0.387 ± 0.014	1.748TyrAsp: 1.748 ± 0.029	1.519TyrGlu: 1.519 ± 0.023	1.157TyrPhe: 1.157 ± 0.023	1.966TyrGly: 1.966 ± 0.039	0.708TyrHis: 0.708 ± 0.016	1.454TyrIle: 1.454 ± 0.025	1.194TyrLys: 1.194 ± 0.023	2.597TyrLeu: 2.597 ± 0.03	0.566TyrMet: 0.566 ± 0.015	1.191TyrAsn: 1.191 ± 0.022	1.497TyrPro: 1.497 ± 0.025	1.072TyrGln: 1.072 ± 0.019	1.631TyrArg: 1.631 ± 0.025	2.058TyrSer: 2.058 ± 0.03	1.638TyrThr: 1.638 ± 0.025	1.569TyrVal: 1.569 ± 0.025	0.38TyrTrp: 0.38 ± 0.011	0.94TyrTyr: 0.94 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5595 proteins (2891906 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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