Amino acid dipepetide frequency for Boseongicola aestuarii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	14.72AlaAla: 14.72 ± 0.141	1.086AlaCys: 1.086 ± 0.032	6.7AlaAsp: 6.7 ± 0.095	7.677AlaGlu: 7.677 ± 0.096	4.671AlaPhe: 4.671 ± 0.071	9.619AlaGly: 9.619 ± 0.105	2.232AlaHis: 2.232 ± 0.046	6.449AlaIle: 6.449 ± 0.085	4.043AlaLys: 4.043 ± 0.062	12.866AlaLeu: 12.866 ± 0.13	3.733AlaMet: 3.733 ± 0.057	2.951AlaAsn: 2.951 ± 0.053	5.253AlaPro: 5.253 ± 0.067	3.709AlaGln: 3.709 ± 0.058	7.981AlaArg: 7.981 ± 0.092	6.135AlaSer: 6.135 ± 0.069	5.998AlaThr: 5.998 ± 0.071	8.182AlaVal: 8.182 ± 0.09	1.459AlaTrp: 1.459 ± 0.034	2.488AlaTyr: 2.488 ± 0.047	0.0AlaXaa: 0.0 ± 0.0
Cys	0.99CysAla: 0.99 ± 0.029	0.111CysCys: 0.111 ± 0.009	0.598CysAsp: 0.598 ± 0.021	0.495CysGlu: 0.495 ± 0.021	0.333CysPhe: 0.333 ± 0.016	0.97CysGly: 0.97 ± 0.028	0.265CysHis: 0.265 ± 0.016	0.442CysIle: 0.442 ± 0.018	0.196CysLys: 0.196 ± 0.012	0.908CysLeu: 0.908 ± 0.027	0.161CysMet: 0.161 ± 0.013	0.215CysAsn: 0.215 ± 0.015	0.473CysPro: 0.473 ± 0.02	0.231CysGln: 0.231 ± 0.012	0.583CysArg: 0.583 ± 0.021	0.473CysSer: 0.473 ± 0.021	0.437CysThr: 0.437 ± 0.02	0.65CysVal: 0.65 ± 0.024	0.123CysTrp: 0.123 ± 0.01	0.207CysTyr: 0.207 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	7.363AspAla: 7.363 ± 0.079	0.543AspCys: 0.543 ± 0.021	3.586AspAsp: 3.586 ± 0.083	3.841AspGlu: 3.841 ± 0.062	2.497AspPhe: 2.497 ± 0.051	5.389AspGly: 5.389 ± 0.069	1.305AspHis: 1.305 ± 0.034	3.546AspIle: 3.546 ± 0.05	1.728AspLys: 1.728 ± 0.04	6.172AspLeu: 6.172 ± 0.075	1.657AspMet: 1.657 ± 0.04	1.337AspAsn: 1.337 ± 0.032	3.508AspPro: 3.508 ± 0.051	1.822AspGln: 1.822 ± 0.04	4.072AspArg: 4.072 ± 0.056	2.149AspSer: 2.149 ± 0.043	3.029AspThr: 3.029 ± 0.054	4.705AspVal: 4.705 ± 0.064	1.158AspTrp: 1.158 ± 0.032	1.524AspTyr: 1.524 ± 0.033	0.0AspXaa: 0.0 ± 0.0
Glu	7.806GluAla: 7.806 ± 0.083	0.4GluCys: 0.4 ± 0.018	3.545GluAsp: 3.545 ± 0.073	3.333GluGlu: 3.333 ± 0.069	2.016GluPhe: 2.016 ± 0.042	4.678GluGly: 4.678 ± 0.072	1.139GluHis: 1.139 ± 0.034	3.977GluIle: 3.977 ± 0.062	2.311GluLys: 2.311 ± 0.047	5.139GluLeu: 5.139 ± 0.069	1.827GluMet: 1.827 ± 0.043	2.015GluAsn: 2.015 ± 0.041	2.515GluPro: 2.515 ± 0.047	1.711GluGln: 1.711 ± 0.044	4.228GluArg: 4.228 ± 0.072	2.511GluSer: 2.511 ± 0.049	4.171GluThr: 4.171 ± 0.06	4.412GluVal: 4.412 ± 0.065	0.788GluTrp: 0.788 ± 0.023	1.085GluTyr: 1.085 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	4.627PheAla: 4.627 ± 0.067	0.477PheCys: 0.477 ± 0.02	2.934PheAsp: 2.934 ± 0.054	2.534PheGlu: 2.534 ± 0.048	1.637PhePhe: 1.637 ± 0.041	3.966PheGly: 3.966 ± 0.058	0.762PheHis: 0.762 ± 0.027	1.881PheIle: 1.881 ± 0.044	1.094PheLys: 1.094 ± 0.031	3.811PheLeu: 3.811 ± 0.069	0.914PheMet: 0.914 ± 0.029	1.142PheAsn: 1.142 ± 0.03	1.616PhePro: 1.616 ± 0.04	1.158PheGln: 1.158 ± 0.034	2.304PheArg: 2.304 ± 0.045	2.39PheSer: 2.39 ± 0.048	2.11PheThr: 2.11 ± 0.039	3.012PheVal: 3.012 ± 0.057	0.661PheTrp: 0.661 ± 0.028	0.924PheTyr: 0.924 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	9.374GlyAla: 9.374 ± 0.099	0.863GlyCys: 0.863 ± 0.03	4.741GlyAsp: 4.741 ± 0.076	4.671GlyGlu: 4.671 ± 0.063	3.865GlyPhe: 3.865 ± 0.067	7.242GlyGly: 7.242 ± 0.1	1.854GlyHis: 1.854 ± 0.041	4.716GlyIle: 4.716 ± 0.068	3.139GlyLys: 3.139 ± 0.065	8.849GlyLeu: 8.849 ± 0.093	2.446GlyMet: 2.446 ± 0.045	2.189GlyAsn: 2.189 ± 0.051	3.432GlyPro: 3.432 ± 0.054	2.891GlyGln: 2.891 ± 0.053	5.399GlyArg: 5.399 ± 0.067	4.295GlySer: 4.295 ± 0.057	4.706GlyThr: 4.706 ± 0.061	6.511GlyVal: 6.511 ± 0.087	1.44GlyTrp: 1.44 ± 0.034	2.281GlyTyr: 2.281 ± 0.042	0.0GlyXaa: 0.0 ± 0.0
His	2.189HisAla: 2.189 ± 0.047	0.236HisCys: 0.236 ± 0.016	1.155HisAsp: 1.155 ± 0.032	1.084HisGlu: 1.084 ± 0.03	0.908HisPhe: 0.908 ± 0.027	1.762HisGly: 1.762 ± 0.042	0.547HisHis: 0.547 ± 0.022	1.084HisIle: 1.084 ± 0.033	0.59HisLys: 0.59 ± 0.025	2.075HisLeu: 2.075 ± 0.045	0.556HisMet: 0.556 ± 0.024	0.482HisAsn: 0.482 ± 0.022	1.265HisPro: 1.265 ± 0.037	0.622HisGln: 0.622 ± 0.023	1.277HisArg: 1.277 ± 0.037	0.977HisSer: 0.977 ± 0.032	0.854HisThr: 0.854 ± 0.026	1.495HisVal: 1.495 ± 0.038	0.317HisTrp: 0.317 ± 0.016	0.512HisTyr: 0.512 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	7.509IleAla: 7.509 ± 0.084	0.619IleCys: 0.619 ± 0.026	3.744IleAsp: 3.744 ± 0.057	3.894IleGlu: 3.894 ± 0.058	1.998IlePhe: 1.998 ± 0.046	5.106IleGly: 5.106 ± 0.063	0.927IleHis: 0.927 ± 0.031	2.647IleIle: 2.647 ± 0.049	1.577IleLys: 1.577 ± 0.038	5.156IleLeu: 5.156 ± 0.078	1.217IleMet: 1.217 ± 0.034	1.516IleAsn: 1.516 ± 0.038	2.474IlePro: 2.474 ± 0.05	1.306IleGln: 1.306 ± 0.036	3.178IleArg: 3.178 ± 0.056	3.43IleSer: 3.43 ± 0.06	3.032IleThr: 3.032 ± 0.048	4.296IleVal: 4.296 ± 0.07	0.802IleTrp: 0.802 ± 0.025	1.234IleTyr: 1.234 ± 0.033	0.0IleXaa: 0.0 ± 0.0
Lys	4.125LysAla: 4.125 ± 0.066	0.195LysCys: 0.195 ± 0.014	1.948LysAsp: 1.948 ± 0.046	1.631LysGlu: 1.631 ± 0.041	0.969LysPhe: 0.969 ± 0.026	2.836LysGly: 2.836 ± 0.051	0.697LysHis: 0.697 ± 0.023	1.883LysIle: 1.883 ± 0.038	1.38LysLys: 1.38 ± 0.042	2.999LysLeu: 2.999 ± 0.057	0.957LysMet: 0.957 ± 0.032	0.971LysAsn: 0.971 ± 0.032	1.866LysPro: 1.866 ± 0.043	0.882LysGln: 0.882 ± 0.027	2.375LysArg: 2.375 ± 0.049	2.299LysSer: 2.299 ± 0.047	2.111LysThr: 2.111 ± 0.045	2.408LysVal: 2.408 ± 0.047	0.434LysTrp: 0.434 ± 0.019	0.673LysTyr: 0.673 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	12.143LeuAla: 12.143 ± 0.107	0.898LeuCys: 0.898 ± 0.032	5.878LeuAsp: 5.878 ± 0.084	5.599LeuGlu: 5.599 ± 0.072	3.797LeuPhe: 3.797 ± 0.069	8.222LeuGly: 8.222 ± 0.086	1.735LeuHis: 1.735 ± 0.045	5.416LeuIle: 5.416 ± 0.072	3.613LeuLys: 3.613 ± 0.053	8.517LeuLeu: 8.517 ± 0.117	2.629LeuMet: 2.629 ± 0.05	2.89LeuAsn: 2.89 ± 0.048	5.161LeuPro: 5.161 ± 0.069	2.665LeuGln: 2.665 ± 0.048	6.272LeuArg: 6.272 ± 0.078	6.676LeuSer: 6.676 ± 0.076	5.958LeuThr: 5.958 ± 0.069	7.116LeuVal: 7.116 ± 0.086	1.281LeuTrp: 1.281 ± 0.034	1.957LeuTyr: 1.957 ± 0.044	0.0LeuXaa: 0.0 ± 0.0
Met	3.238MetAla: 3.238 ± 0.053	0.174MetCys: 0.174 ± 0.011	1.413MetAsp: 1.413 ± 0.029	1.334MetGlu: 1.334 ± 0.036	0.846MetPhe: 0.846 ± 0.029	2.201MetGly: 2.201 ± 0.049	0.486MetHis: 0.486 ± 0.022	1.624MetIle: 1.624 ± 0.038	1.137MetLys: 1.137 ± 0.032	2.471MetLeu: 2.471 ± 0.047	0.8MetMet: 0.8 ± 0.027	0.941MetAsn: 0.941 ± 0.027	1.432MetPro: 1.432 ± 0.029	0.901MetGln: 0.901 ± 0.027	1.848MetArg: 1.848 ± 0.039	1.939MetSer: 1.939 ± 0.041	2.183MetThr: 2.183 ± 0.045	1.961MetVal: 1.961 ± 0.039	0.274MetTrp: 0.274 ± 0.016	0.393MetTyr: 0.393 ± 0.019	0.0MetXaa: 0.0 ± 0.0
Asn	3.39AsnAla: 3.39 ± 0.055	0.278AsnCys: 0.278 ± 0.015	1.603AsnAsp: 1.603 ± 0.041	1.504AsnGlu: 1.504 ± 0.036	1.072AsnPhe: 1.072 ± 0.031	2.457AsnGly: 2.457 ± 0.046	0.545AsnHis: 0.545 ± 0.02	1.603AsnIle: 1.603 ± 0.037	0.753AsnLys: 0.753 ± 0.025	2.608AsnLeu: 2.608 ± 0.05	0.72AsnMet: 0.72 ± 0.029	0.767AsnAsn: 0.767 ± 0.028	1.902AsnPro: 1.902 ± 0.044	0.745AsnGln: 0.745 ± 0.022	1.841AsnArg: 1.841 ± 0.04	1.342AsnSer: 1.342 ± 0.037	1.473AsnThr: 1.473 ± 0.041	2.103AsnVal: 2.103 ± 0.045	0.491AsnTrp: 0.491 ± 0.021	0.699AsnTyr: 0.699 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	4.857ProAla: 4.857 ± 0.066	0.34ProCys: 0.34 ± 0.016	3.757ProAsp: 3.757 ± 0.054	3.949ProGlu: 3.949 ± 0.07	2.026ProPhe: 2.026 ± 0.038	4.185ProGly: 4.185 ± 0.068	1.044ProHis: 1.044 ± 0.034	2.516ProIle: 2.516 ± 0.049	1.835ProLys: 1.835 ± 0.044	4.394ProLeu: 4.394 ± 0.062	1.292ProMet: 1.292 ± 0.032	1.507ProAsn: 1.507 ± 0.038	2.141ProPro: 2.141 ± 0.044	1.308ProGln: 1.308 ± 0.037	2.473ProArg: 2.473 ± 0.044	2.732ProSer: 2.732 ± 0.048	2.554ProThr: 2.554 ± 0.04	4.008ProVal: 4.008 ± 0.055	0.645ProTrp: 0.645 ± 0.025	1.089ProTyr: 1.089 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.559GlnAla: 3.559 ± 0.056	0.194GlnCys: 0.194 ± 0.014	1.633GlnAsp: 1.633 ± 0.039	1.392GlnGlu: 1.392 ± 0.035	1.122GlnPhe: 1.122 ± 0.032	2.229GlnGly: 2.229 ± 0.039	0.519GlnHis: 0.519 ± 0.02	1.937GlnIle: 1.937 ± 0.037	1.145GlnLys: 1.145 ± 0.03	2.481GlnLeu: 2.481 ± 0.042	0.98GlnMet: 0.98 ± 0.028	0.959GlnAsn: 0.959 ± 0.028	1.401GlnPro: 1.401 ± 0.033	0.926GlnGln: 0.926 ± 0.037	2.009GlnArg: 2.009 ± 0.04	1.933GlnSer: 1.933 ± 0.037	1.833GlnThr: 1.833 ± 0.039	2.187GlnVal: 2.187 ± 0.044	0.364GlnTrp: 0.364 ± 0.019	0.59GlnTyr: 0.59 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	7.414ArgAla: 7.414 ± 0.086	0.467ArgCys: 0.467 ± 0.02	4.037ArgAsp: 4.037 ± 0.055	3.751ArgGlu: 3.751 ± 0.058	2.704ArgPhe: 2.704 ± 0.053	4.418ArgGly: 4.418 ± 0.053	1.421ArgHis: 1.421 ± 0.038	3.767ArgIle: 3.767 ± 0.061	2.243ArgLys: 2.243 ± 0.042	6.866ArgLeu: 6.866 ± 0.088	1.829ArgMet: 1.829 ± 0.034	1.816ArgAsn: 1.816 ± 0.037	3.017ArgPro: 3.017 ± 0.05	2.163ArgGln: 2.163 ± 0.042	4.667ArgArg: 4.667 ± 0.077	3.339ArgSer: 3.339 ± 0.054	3.126ArgThr: 3.126 ± 0.055	4.733ArgVal: 4.733 ± 0.065	0.902ArgTrp: 0.902 ± 0.034	1.496ArgTyr: 1.496 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	5.961SerAla: 5.961 ± 0.085	0.443SerCys: 0.443 ± 0.02	3.648SerAsp: 3.648 ± 0.056	3.345SerGlu: 3.345 ± 0.049	2.457SerPhe: 2.457 ± 0.045	5.597SerGly: 5.597 ± 0.065	1.125SerHis: 1.125 ± 0.031	2.901SerIle: 2.901 ± 0.047	1.839SerLys: 1.839 ± 0.038	5.404SerLeu: 5.404 ± 0.066	1.536SerMet: 1.536 ± 0.039	1.597SerAsn: 1.597 ± 0.04	2.577SerPro: 2.577 ± 0.052	1.665SerGln: 1.665 ± 0.035	3.402SerArg: 3.402 ± 0.05	2.808SerSer: 2.808 ± 0.052	2.757SerThr: 2.757 ± 0.047	4.288SerVal: 4.288 ± 0.067	0.692SerTrp: 0.692 ± 0.023	1.281SerTyr: 1.281 ± 0.03	0.0SerXaa: 0.0 ± 0.0
Thr	5.933ThrAla: 5.933 ± 0.078	0.508ThrCys: 0.508 ± 0.021	3.378ThrAsp: 3.378 ± 0.048	2.96ThrGlu: 2.96 ± 0.053	2.243ThrPhe: 2.243 ± 0.038	5.182ThrGly: 5.182 ± 0.07	1.164ThrHis: 1.164 ± 0.037	3.105ThrIle: 3.105 ± 0.047	1.71ThrLys: 1.71 ± 0.042	6.197ThrLeu: 6.197 ± 0.08	1.352ThrMet: 1.352 ± 0.031	1.526ThrAsn: 1.526 ± 0.042	3.371ThrPro: 3.371 ± 0.056	1.525ThrGln: 1.525 ± 0.034	3.403ThrArg: 3.403 ± 0.054	3.143ThrSer: 3.143 ± 0.062	2.981ThrThr: 2.981 ± 0.053	4.255ThrVal: 4.255 ± 0.076	0.73ThrTrp: 0.73 ± 0.025	1.288ThrTyr: 1.288 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	8.889ValAla: 8.889 ± 0.11	0.637ValCys: 0.637 ± 0.023	4.311ValAsp: 4.311 ± 0.056	4.64ValGlu: 4.64 ± 0.066	3.216ValPhe: 3.216 ± 0.058	5.719ValGly: 5.719 ± 0.077	1.376ValHis: 1.376 ± 0.035	4.365ValIle: 4.365 ± 0.067	2.226ValLys: 2.226 ± 0.044	7.509ValLeu: 7.509 ± 0.097	2.133ValMet: 2.133 ± 0.04	2.026ValAsn: 2.026 ± 0.041	3.534ValPro: 3.534 ± 0.05	1.996ValGln: 1.996 ± 0.041	4.374ValArg: 4.374 ± 0.07	4.608ValSer: 4.608 ± 0.075	4.712ValThr: 4.712 ± 0.065	5.793ValVal: 5.793 ± 0.088	1.016ValTrp: 1.016 ± 0.033	1.608ValTyr: 1.608 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.391TrpAla: 1.391 ± 0.034	0.153TrpCys: 0.153 ± 0.011	0.822TrpAsp: 0.822 ± 0.028	0.682TrpGlu: 0.682 ± 0.021	0.579TrpPhe: 0.579 ± 0.021	1.016TrpGly: 1.016 ± 0.029	0.348TrpHis: 0.348 ± 0.016	0.805TrpIle: 0.805 ± 0.031	0.469TrpLys: 0.469 ± 0.02	1.688TrpLeu: 1.688 ± 0.043	0.387TrpMet: 0.387 ± 0.019	0.455TrpAsn: 0.455 ± 0.018	0.654TrpPro: 0.654 ± 0.026	0.509TrpGln: 0.509 ± 0.027	1.015TrpArg: 1.015 ± 0.031	0.908TrpSer: 0.908 ± 0.026	0.809TrpThr: 0.809 ± 0.023	0.95TrpVal: 0.95 ± 0.031	0.229TrpTrp: 0.229 ± 0.013	0.31TrpTyr: 0.31 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.476TyrAla: 2.476 ± 0.047	0.238TyrCys: 0.238 ± 0.015	1.5TyrAsp: 1.5 ± 0.037	1.293TyrGlu: 1.293 ± 0.038	0.997TyrPhe: 0.997 ± 0.032	2.112TyrGly: 2.112 ± 0.046	0.495TyrHis: 0.495 ± 0.02	0.994TyrIle: 0.994 ± 0.029	0.612TyrLys: 0.612 ± 0.022	2.315TyrLeu: 2.315 ± 0.041	0.47TyrMet: 0.47 ± 0.021	0.595TyrAsn: 0.595 ± 0.023	1.06TyrPro: 1.06 ± 0.03	0.657TyrGln: 0.657 ± 0.022	1.473TyrArg: 1.473 ± 0.037	1.234TyrSer: 1.234 ± 0.03	1.119TyrThr: 1.119 ± 0.029	1.624TyrVal: 1.624 ± 0.035	0.374TyrTrp: 0.374 ± 0.018	0.584TyrTyr: 0.584 ± 0.022	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4011 proteins (1184372 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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