Amino acid dipepetide frequency for Lentzea albidocapillata

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.542AlaAla: 17.542 ± 0.124	1.031AlaCys: 1.031 ± 0.019	7.542AlaAsp: 7.542 ± 0.067	8.126AlaGlu: 8.126 ± 0.078	3.641AlaPhe: 3.641 ± 0.04	11.671AlaGly: 11.671 ± 0.072	2.499AlaHis: 2.499 ± 0.036	4.283AlaIle: 4.283 ± 0.052	3.253AlaLys: 3.253 ± 0.041	13.676AlaLeu: 13.676 ± 0.093	2.551AlaMet: 2.551 ± 0.034	2.505AlaAsn: 2.505 ± 0.036	5.573AlaPro: 5.573 ± 0.065	3.852AlaGln: 3.852 ± 0.046	8.71AlaArg: 8.71 ± 0.073	6.226AlaSer: 6.226 ± 0.056	6.754AlaThr: 6.754 ± 0.059	11.616AlaVal: 11.616 ± 0.093	1.815AlaTrp: 1.815 ± 0.028	2.273AlaTyr: 2.273 ± 0.03	0.0AlaXaa: 0.0 ± 0.0
Cys	1.008CysAla: 1.008 ± 0.023	0.098CysCys: 0.098 ± 0.007	0.472CysAsp: 0.472 ± 0.014	0.4CysGlu: 0.4 ± 0.012	0.218CysPhe: 0.218 ± 0.01	0.991CysGly: 0.991 ± 0.021	0.192CysHis: 0.192 ± 0.009	0.182CysIle: 0.182 ± 0.009	0.124CysLys: 0.124 ± 0.007	0.721CysLeu: 0.721 ± 0.018	0.129CysMet: 0.129 ± 0.007	0.157CysAsn: 0.157 ± 0.008	0.467CysPro: 0.467 ± 0.016	0.214CysGln: 0.214 ± 0.009	0.577CysArg: 0.577 ± 0.018	0.511CysSer: 0.511 ± 0.014	0.495CysThr: 0.495 ± 0.015	0.713CysVal: 0.713 ± 0.018	0.129CysTrp: 0.129 ± 0.007	0.167CysTyr: 0.167 ± 0.009	0.0CysXaa: 0.0 ± 0.0
Asp	6.92AspAla: 6.92 ± 0.063	0.405AspCys: 0.405 ± 0.012	3.598AspAsp: 3.598 ± 0.048	4.013AspGlu: 4.013 ± 0.047	1.755AspPhe: 1.755 ± 0.027	5.851AspGly: 5.851 ± 0.059	1.404AspHis: 1.404 ± 0.023	1.866AspIle: 1.866 ± 0.029	1.302AspLys: 1.302 ± 0.026	6.576AspLeu: 6.576 ± 0.061	0.87AspMet: 0.87 ± 0.018	1.222AspAsn: 1.222 ± 0.025	3.933AspPro: 3.933 ± 0.038	1.806AspGln: 1.806 ± 0.031	4.54AspArg: 4.54 ± 0.054	2.681AspSer: 2.681 ± 0.033	2.814AspThr: 2.814 ± 0.038	5.726AspVal: 5.726 ± 0.052	0.967AspTrp: 0.967 ± 0.02	1.174AspTyr: 1.174 ± 0.024	0.0AspXaa: 0.0 ± 0.0
Glu	6.648GluAla: 6.648 ± 0.062	0.36GluCys: 0.36 ± 0.012	2.717GluAsp: 2.717 ± 0.029	3.024GluGlu: 3.024 ± 0.041	1.857GluPhe: 1.857 ± 0.029	3.55GluGly: 3.55 ± 0.038	1.632GluHis: 1.632 ± 0.026	2.608GluIle: 2.608 ± 0.032	1.594GluLys: 1.594 ± 0.028	7.061GluLeu: 7.061 ± 0.065	1.052GluMet: 1.052 ± 0.019	1.282GluAsn: 1.282 ± 0.023	3.182GluPro: 3.182 ± 0.045	2.441GluGln: 2.441 ± 0.033	4.767GluArg: 4.767 ± 0.06	2.68GluSer: 2.68 ± 0.034	2.689GluThr: 2.689 ± 0.036	5.089GluVal: 5.089 ± 0.046	0.846GluTrp: 0.846 ± 0.019	1.066GluTyr: 1.066 ± 0.02	0.0GluXaa: 0.0 ± 0.0
Phe	3.892PheAla: 3.892 ± 0.038	0.264PheCys: 0.264 ± 0.011	2.226PheAsp: 2.226 ± 0.031	1.646PheGlu: 1.646 ± 0.026	0.973PhePhe: 0.973 ± 0.021	3.427PheGly: 3.427 ± 0.039	0.668PheHis: 0.668 ± 0.015	0.808PheIle: 0.808 ± 0.019	0.608PheLys: 0.608 ± 0.016	2.839PheLeu: 2.839 ± 0.036	0.442PheMet: 0.442 ± 0.013	0.675PheAsn: 0.675 ± 0.017	1.413PhePro: 1.413 ± 0.023	0.795PheGln: 0.795 ± 0.018	1.929PheArg: 1.929 ± 0.026	1.768PheSer: 1.768 ± 0.028	2.173PheThr: 2.173 ± 0.029	2.76PheVal: 2.76 ± 0.039	0.451PheTrp: 0.451 ± 0.013	0.677PheTyr: 0.677 ± 0.018	0.0PheXaa: 0.0 ± 0.0
Gly	9.37GlyAla: 9.37 ± 0.071	0.819GlyCys: 0.819 ± 0.02	4.992GlyAsp: 4.992 ± 0.055	4.859GlyGlu: 4.859 ± 0.056	3.08GlyPhe: 3.08 ± 0.038	7.741GlyGly: 7.741 ± 0.08	2.037GlyHis: 2.037 ± 0.032	3.55GlyIle: 3.55 ± 0.044	2.793GlyLys: 2.793 ± 0.036	9.044GlyLeu: 9.044 ± 0.077	2.008GlyMet: 2.008 ± 0.029	2.093GlyAsn: 2.093 ± 0.039	4.228GlyPro: 4.228 ± 0.047	2.851GlyGln: 2.851 ± 0.035	6.335GlyArg: 6.335 ± 0.054	5.177GlySer: 5.177 ± 0.054	5.775GlyThr: 5.775 ± 0.054	8.008GlyVal: 8.008 ± 0.071	1.687GlyTrp: 1.687 ± 0.025	2.262GlyTyr: 2.262 ± 0.034	0.0GlyXaa: 0.0 ± 0.0
His	2.511HisAla: 2.511 ± 0.032	0.216HisCys: 0.216 ± 0.01	1.433HisAsp: 1.433 ± 0.024	1.312HisGlu: 1.312 ± 0.021	0.639HisPhe: 0.639 ± 0.018	2.28HisGly: 2.28 ± 0.034	0.677HisHis: 0.677 ± 0.022	0.626HisIle: 0.626 ± 0.016	0.403HisLys: 0.403 ± 0.013	2.35HisLeu: 2.35 ± 0.036	0.336HisMet: 0.336 ± 0.012	0.522HisAsn: 0.522 ± 0.014	1.489HisPro: 1.489 ± 0.023	0.7HisGln: 0.7 ± 0.017	1.898HisArg: 1.898 ± 0.032	1.047HisSer: 1.047 ± 0.021	1.163HisThr: 1.163 ± 0.023	1.991HisVal: 1.991 ± 0.032	0.363HisTrp: 0.363 ± 0.012	0.495HisTyr: 0.495 ± 0.012	0.0HisXaa: 0.0 ± 0.0
Ile	5.501IleAla: 5.501 ± 0.056	0.29IleCys: 0.29 ± 0.01	2.555IleAsp: 2.555 ± 0.03	2.234IleGlu: 2.234 ± 0.03	0.851IlePhe: 0.851 ± 0.023	3.939IleGly: 3.939 ± 0.043	0.602IleHis: 0.602 ± 0.015	1.128IleIle: 1.128 ± 0.025	0.929IleLys: 0.929 ± 0.021	2.318IleLeu: 2.318 ± 0.03	0.544IleMet: 0.544 ± 0.015	0.944IleAsn: 0.944 ± 0.022	1.895IlePro: 1.895 ± 0.03	0.782IleGln: 0.782 ± 0.02	2.351IleArg: 2.351 ± 0.031	2.115IleSer: 2.115 ± 0.035	2.756IleThr: 2.756 ± 0.035	3.232IleVal: 3.232 ± 0.041	0.438IleTrp: 0.438 ± 0.014	0.648IleTyr: 0.648 ± 0.017	0.0IleXaa: 0.0 ± 0.0
Lys	3.297LysAla: 3.297 ± 0.038	0.156LysCys: 0.156 ± 0.009	1.359LysAsp: 1.359 ± 0.026	1.138LysGlu: 1.138 ± 0.022	0.735LysPhe: 0.735 ± 0.02	1.819LysGly: 1.819 ± 0.034	0.556LysHis: 0.556 ± 0.014	1.186LysIle: 1.186 ± 0.024	0.843LysLys: 0.843 ± 0.025	2.686LysLeu: 2.686 ± 0.037	0.454LysMet: 0.454 ± 0.015	0.587LysAsn: 0.587 ± 0.017	1.723LysPro: 1.723 ± 0.029	0.867LysGln: 0.867 ± 0.021	1.734LysArg: 1.734 ± 0.028	1.415LysSer: 1.415 ± 0.025	1.442LysThr: 1.442 ± 0.026	2.291LysVal: 2.291 ± 0.038	0.386LysTrp: 0.386 ± 0.013	0.55LysTyr: 0.55 ± 0.016	0.0LysXaa: 0.0 ± 0.0
Leu	14.357LeuAla: 14.357 ± 0.109	0.822LeuCys: 0.822 ± 0.015	6.771LeuAsp: 6.771 ± 0.066	4.894LeuGlu: 4.894 ± 0.054	2.805LeuPhe: 2.805 ± 0.037	9.102LeuGly: 9.102 ± 0.071	2.325LeuHis: 2.325 ± 0.031	3.563LeuIle: 3.563 ± 0.047	2.425LeuLys: 2.425 ± 0.032	11.055LeuLeu: 11.055 ± 0.112	1.667LeuMet: 1.667 ± 0.029	2.077LeuAsn: 2.077 ± 0.03	6.049LeuPro: 6.049 ± 0.057	2.56LeuGln: 2.56 ± 0.032	8.42LeuArg: 8.42 ± 0.077	5.771LeuSer: 5.771 ± 0.052	6.672LeuThr: 6.672 ± 0.059	9.816LeuVal: 9.816 ± 0.075	1.327LeuTrp: 1.327 ± 0.025	1.68LeuTyr: 1.68 ± 0.025	0.0LeuXaa: 0.0 ± 0.0
Met	2.21MetAla: 2.21 ± 0.026	0.141MetCys: 0.141 ± 0.008	0.866MetAsp: 0.866 ± 0.019	0.716MetGlu: 0.716 ± 0.018	0.571MetPhe: 0.571 ± 0.014	1.275MetGly: 1.275 ± 0.025	0.395MetHis: 0.395 ± 0.011	0.858MetIle: 0.858 ± 0.017	0.546MetLys: 0.546 ± 0.015	1.892MetLeu: 1.892 ± 0.03	0.308MetMet: 0.308 ± 0.01	0.49MetAsn: 0.49 ± 0.016	1.129MetPro: 1.129 ± 0.021	0.499MetGln: 0.499 ± 0.014	1.575MetArg: 1.575 ± 0.028	1.409MetSer: 1.409 ± 0.025	1.582MetThr: 1.582 ± 0.022	1.451MetVal: 1.451 ± 0.028	0.261MetTrp: 0.261 ± 0.009	0.297MetTyr: 0.297 ± 0.011	0.0MetXaa: 0.0 ± 0.0
Asn	2.771AsnAla: 2.771 ± 0.04	0.199AsnCys: 0.199 ± 0.009	1.235AsnAsp: 1.235 ± 0.024	1.083AsnGlu: 1.083 ± 0.021	0.625AsnPhe: 0.625 ± 0.017	2.473AsnGly: 2.473 ± 0.042	0.474AsnHis: 0.474 ± 0.015	0.768AsnIle: 0.768 ± 0.02	0.54AsnLys: 0.54 ± 0.015	2.012AsnLeu: 2.012 ± 0.032	0.345AsnMet: 0.345 ± 0.01	0.633AsnAsn: 0.633 ± 0.022	1.646AsnPro: 1.646 ± 0.03	0.654AsnGln: 0.654 ± 0.017	1.511AsnArg: 1.511 ± 0.031	1.233AsnSer: 1.233 ± 0.026	1.327AsnThr: 1.327 ± 0.027	1.843AsnVal: 1.843 ± 0.028	0.388AsnTrp: 0.388 ± 0.013	0.536AsnTyr: 0.536 ± 0.015	0.0AsnXaa: 0.0 ± 0.0
Pro	7.024ProAla: 7.024 ± 0.069	0.365ProCys: 0.365 ± 0.011	4.052ProAsp: 4.052 ± 0.055	3.819ProGlu: 3.819 ± 0.048	1.652ProPhe: 1.652 ± 0.025	5.49ProGly: 5.49 ± 0.06	1.227ProHis: 1.227 ± 0.024	1.676ProIle: 1.676 ± 0.029	1.415ProLys: 1.415 ± 0.028	4.989ProLeu: 4.989 ± 0.046	1.05ProMet: 1.05 ± 0.019	1.262ProAsn: 1.262 ± 0.027	3.064ProPro: 3.064 ± 0.062	1.687ProGln: 1.687 ± 0.029	3.364ProArg: 3.364 ± 0.045	3.373ProSer: 3.373 ± 0.047	2.873ProThr: 2.873 ± 0.038	5.249ProVal: 5.249 ± 0.059	0.856ProTrp: 0.856 ± 0.02	1.005ProTyr: 1.005 ± 0.018	0.0ProXaa: 0.0 ± 0.0
Gln	3.924GlnAla: 3.924 ± 0.05	0.214GlnCys: 0.214 ± 0.009	1.457GlnAsp: 1.457 ± 0.023	1.504GlnGlu: 1.504 ± 0.03	0.887GlnPhe: 0.887 ± 0.021	2.199GlnGly: 2.199 ± 0.035	0.736GlnHis: 0.736 ± 0.016	1.259GlnIle: 1.259 ± 0.02	0.755GlnLys: 0.755 ± 0.019	3.278GlnLeu: 3.278 ± 0.037	0.548GlnMet: 0.548 ± 0.016	0.699GlnAsn: 0.699 ± 0.017	1.826GlnPro: 1.826 ± 0.033	1.439GlnGln: 1.439 ± 0.035	2.708GlnArg: 2.708 ± 0.037	1.436GlnSer: 1.436 ± 0.027	1.45GlnThr: 1.45 ± 0.024	2.82GlnVal: 2.82 ± 0.036	0.545GlnTrp: 0.545 ± 0.014	0.607GlnTyr: 0.607 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	8.461ArgAla: 8.461 ± 0.076	0.56ArgCys: 0.56 ± 0.015	4.195ArgAsp: 4.195 ± 0.044	4.35ArgGlu: 4.35 ± 0.049	2.532ArgPhe: 2.532 ± 0.03	5.24ArgGly: 5.24 ± 0.056	1.824ArgHis: 1.824 ± 0.028	3.096ArgIle: 3.096 ± 0.036	2.053ArgLys: 2.053 ± 0.033	7.997ArgLeu: 7.997 ± 0.073	1.847ArgMet: 1.847 ± 0.029	1.672ArgAsn: 1.672 ± 0.028	3.951ArgPro: 3.951 ± 0.05	2.399ArgGln: 2.399 ± 0.031	6.423ArgArg: 6.423 ± 0.072	4.104ArgSer: 4.104 ± 0.046	4.757ArgThr: 4.757 ± 0.043	5.951ArgVal: 5.951 ± 0.06	1.395ArgTrp: 1.395 ± 0.029	1.763ArgTyr: 1.763 ± 0.028	0.0ArgXaa: 0.0 ± 0.0
Ser	6.708SerAla: 6.708 ± 0.055	0.477SerCys: 0.477 ± 0.014	2.945SerAsp: 2.945 ± 0.037	2.738SerGlu: 2.738 ± 0.034	1.796SerPhe: 1.796 ± 0.028	5.951SerGly: 5.951 ± 0.06	1.059SerHis: 1.059 ± 0.02	1.911SerIle: 1.911 ± 0.03	1.317SerLys: 1.317 ± 0.022	5.318SerLeu: 5.318 ± 0.044	1.253SerMet: 1.253 ± 0.023	1.206SerAsn: 1.206 ± 0.023	3.067SerPro: 3.067 ± 0.044	1.431SerGln: 1.431 ± 0.029	3.818SerArg: 3.818 ± 0.045	3.478SerSer: 3.478 ± 0.047	3.547SerThr: 3.547 ± 0.043	4.811SerVal: 4.811 ± 0.051	1.075SerTrp: 1.075 ± 0.019	1.269SerTyr: 1.269 ± 0.024	0.0SerXaa: 0.0 ± 0.0
Thr	7.768ThrAla: 7.768 ± 0.064	0.497ThrCys: 0.497 ± 0.015	3.289ThrAsp: 3.289 ± 0.04	3.173ThrGlu: 3.173 ± 0.041	1.888ThrPhe: 1.888 ± 0.029	6.152ThrGly: 6.152 ± 0.058	1.21ThrHis: 1.21 ± 0.022	2.209ThrIle: 2.209 ± 0.031	1.453ThrLys: 1.453 ± 0.029	5.517ThrLeu: 5.517 ± 0.048	1.01ThrMet: 1.01 ± 0.02	1.336ThrAsn: 1.336 ± 0.025	3.811ThrPro: 3.811 ± 0.05	1.476ThrGln: 1.476 ± 0.024	3.763ThrArg: 3.763 ± 0.039	3.633ThrSer: 3.633 ± 0.041	4.214ThrThr: 4.214 ± 0.063	5.767ThrVal: 5.767 ± 0.052	0.997ThrTrp: 0.997 ± 0.02	1.307ThrTyr: 1.307 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	11.25ValAla: 11.25 ± 0.077	0.721ValCys: 0.721 ± 0.018	5.562ValAsp: 5.562 ± 0.044	5.294ValGlu: 5.294 ± 0.054	2.645ValPhe: 2.645 ± 0.039	6.562ValGly: 6.562 ± 0.061	2.125ValHis: 2.125 ± 0.03	3.393ValIle: 3.393 ± 0.039	2.065ValLys: 2.065 ± 0.03	10.696ValLeu: 10.696 ± 0.094	1.465ValMet: 1.465 ± 0.025	1.97ValAsn: 1.97 ± 0.028	5.222ValPro: 5.222 ± 0.059	2.458ValGln: 2.458 ± 0.031	7.011ValArg: 7.011 ± 0.06	4.991ValSer: 4.991 ± 0.052	5.767ValThr: 5.767 ± 0.053	9.594ValVal: 9.594 ± 0.083	1.226ValTrp: 1.226 ± 0.022	1.526ValTyr: 1.526 ± 0.024	0.0ValXaa: 0.0 ± 0.0
Trp	1.635TrpAla: 1.635 ± 0.026	0.151TrpCys: 0.151 ± 0.008	0.839TrpAsp: 0.839 ± 0.018	0.741TrpGlu: 0.741 ± 0.021	0.591TrpPhe: 0.591 ± 0.015	1.055TrpGly: 1.055 ± 0.02	0.409TrpHis: 0.409 ± 0.014	0.613TrpIle: 0.613 ± 0.018	0.394TrpLys: 0.394 ± 0.013	1.931TrpLeu: 1.931 ± 0.028	0.346TrpMet: 0.346 ± 0.011	0.492TrpAsn: 0.492 ± 0.015	0.788TrpPro: 0.788 ± 0.02	0.705TrpGln: 0.705 ± 0.019	1.333TrpArg: 1.333 ± 0.024	1.005TrpSer: 1.005 ± 0.021	1.066TrpThr: 1.066 ± 0.023	1.095TrpVal: 1.095 ± 0.024	0.373TrpTrp: 0.373 ± 0.012	0.325TrpTyr: 0.325 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.34TyrAla: 2.34 ± 0.031	0.178TyrCys: 0.178 ± 0.008	1.322TyrAsp: 1.322 ± 0.033	1.079TyrGlu: 1.079 ± 0.02	0.693TyrPhe: 0.693 ± 0.017	1.942TyrGly: 1.942 ± 0.028	0.397TyrHis: 0.397 ± 0.011	0.468TyrIle: 0.468 ± 0.015	0.411TyrLys: 0.411 ± 0.014	2.205TyrLeu: 2.205 ± 0.029	0.246TyrMet: 0.246 ± 0.009	0.47TyrAsn: 0.47 ± 0.014	1.036TyrPro: 1.036 ± 0.022	0.676TyrGln: 0.676 ± 0.015	1.805TyrArg: 1.805 ± 0.033	1.124TyrSer: 1.124 ± 0.022	1.156TyrThr: 1.156 ± 0.026	1.718TyrVal: 1.718 ± 0.029	0.363TyrTrp: 0.363 ± 0.013	0.486TyrTyr: 0.486 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 8155 proteins (2634138 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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