Amino acid dipepetide frequency for Haplochromis burtoni (Burton s mouthbrooder) (Chromis burtoni)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	6.039AlaAla: 6.039 ± 0.028	1.272AlaCys: 1.272 ± 0.011	3.125AlaAsp: 3.125 ± 0.013	4.57AlaGlu: 4.57 ± 0.028	2.363AlaPhe: 2.363 ± 0.012	4.171AlaGly: 4.171 ± 0.018	1.493AlaHis: 1.493 ± 0.009	2.724AlaIle: 2.724 ± 0.014	3.412AlaLys: 3.412 ± 0.019	6.329AlaLeu: 6.329 ± 0.023	1.574AlaMet: 1.574 ± 0.008	2.2AlaAsn: 2.2 ± 0.011	3.433AlaPro: 3.433 ± 0.019	2.954AlaGln: 2.954 ± 0.016	3.055AlaArg: 3.055 ± 0.014	5.57AlaSer: 5.57 ± 0.021	3.495AlaThr: 3.495 ± 0.015	4.831AlaVal: 4.831 ± 0.02	0.629AlaTrp: 0.629 ± 0.006	1.509AlaTyr: 1.509 ± 0.01	0.0AlaXaa: 0.0 ± 0.0
Cys	1.172CysAla: 1.172 ± 0.009	0.662CysCys: 0.662 ± 0.007	1.132CysAsp: 1.132 ± 0.01	1.251CysGlu: 1.251 ± 0.011	0.928CysPhe: 0.928 ± 0.007	1.532CysGly: 1.532 ± 0.013	0.652CysHis: 0.652 ± 0.006	0.998CysIle: 0.998 ± 0.009	1.182CysLys: 1.182 ± 0.008	2.136CysLeu: 2.136 ± 0.012	0.478CysMet: 0.478 ± 0.005	0.864CysAsn: 0.864 ± 0.008	1.265CysPro: 1.265 ± 0.012	1.02CysGln: 1.02 ± 0.01	1.24CysArg: 1.24 ± 0.009	2.146CysSer: 2.146 ± 0.015	1.21CysThr: 1.21 ± 0.009	1.516CysVal: 1.516 ± 0.012	0.292CysTrp: 0.292 ± 0.004	0.628CysTyr: 0.628 ± 0.006	0.0CysXaa: 0.0 ± 0.0
Asp	2.901AspAla: 2.901 ± 0.012	1.131AspCys: 1.131 ± 0.01	3.124AspAsp: 3.124 ± 0.02	3.766AspGlu: 3.766 ± 0.019	2.119AspPhe: 2.119 ± 0.012	3.596AspGly: 3.596 ± 0.02	1.183AspHis: 1.183 ± 0.008	2.717AspIle: 2.717 ± 0.013	2.764AspLys: 2.764 ± 0.014	4.903AspLeu: 4.903 ± 0.019	1.284AspMet: 1.284 ± 0.008	1.957AspAsn: 1.957 ± 0.011	2.82AspPro: 2.82 ± 0.013	1.925AspGln: 1.925 ± 0.011	2.724AspArg: 2.724 ± 0.016	4.535AspSer: 4.535 ± 0.019	2.677AspThr: 2.677 ± 0.013	3.204AspVal: 3.204 ± 0.013	0.662AspTrp: 0.662 ± 0.007	1.559AspTyr: 1.559 ± 0.01	0.0AspXaa: 0.0 ± 0.0
Glu	4.673GluAla: 4.673 ± 0.023	1.228GluCys: 1.228 ± 0.011	4.39GluAsp: 4.39 ± 0.02	7.787GluGlu: 7.787 ± 0.049	1.924GluPhe: 1.924 ± 0.011	4.081GluGly: 4.081 ± 0.016	1.468GluHis: 1.468 ± 0.008	2.875GluIle: 2.875 ± 0.014	4.891GluLys: 4.891 ± 0.03	6.119GluLeu: 6.119 ± 0.027	1.762GluMet: 1.762 ± 0.01	2.845GluAsn: 2.845 ± 0.013	2.759GluPro: 2.759 ± 0.016	3.109GluGln: 3.109 ± 0.019	4.263GluArg: 4.263 ± 0.025	4.447GluSer: 4.447 ± 0.02	3.447GluThr: 3.447 ± 0.014	4.266GluVal: 4.266 ± 0.02	0.692GluTrp: 0.692 ± 0.006	1.6GluTyr: 1.6 ± 0.01	0.0GluXaa: 0.0 ± 0.0
Phe	1.895PheAla: 1.895 ± 0.012	0.966PheCys: 0.966 ± 0.008	1.757PheAsp: 1.757 ± 0.011	1.854PheGlu: 1.854 ± 0.011	1.694PhePhe: 1.694 ± 0.013	2.186PheGly: 2.186 ± 0.014	1.024PheHis: 1.024 ± 0.008	1.982PheIle: 1.982 ± 0.013	1.862PheLys: 1.862 ± 0.012	3.888PheLeu: 3.888 ± 0.019	0.835PheMet: 0.835 ± 0.007	1.505PheAsn: 1.505 ± 0.01	1.839PhePro: 1.839 ± 0.01	1.61PheGln: 1.61 ± 0.01	1.834PheArg: 1.834 ± 0.011	3.441PheSer: 3.441 ± 0.016	2.321PheThr: 2.321 ± 0.014	2.232PheVal: 2.232 ± 0.014	0.475PheTrp: 0.475 ± 0.006	1.237PheTyr: 1.237 ± 0.01	0.001PheXaa: 0.001 ± 0.0
Gly	3.887GlyAla: 3.887 ± 0.023	1.219GlyCys: 1.219 ± 0.009	3.184GlyAsp: 3.184 ± 0.016	4.054GlyGlu: 4.054 ± 0.021	2.404GlyPhe: 2.404 ± 0.013	5.281GlyGly: 5.281 ± 0.039	1.657GlyHis: 1.657 ± 0.013	2.65GlyIle: 2.65 ± 0.015	3.614GlyLys: 3.614 ± 0.016	5.367GlyLeu: 5.367 ± 0.019	1.48GlyMet: 1.48 ± 0.012	2.518GlyAsn: 2.518 ± 0.014	3.148GlyPro: 3.148 ± 0.033	2.725GlyGln: 2.725 ± 0.014	3.543GlyArg: 3.543 ± 0.015	5.729GlySer: 5.729 ± 0.024	3.413GlyThr: 3.413 ± 0.017	3.906GlyVal: 3.906 ± 0.016	0.755GlyTrp: 0.755 ± 0.008	1.842GlyTyr: 1.842 ± 0.012	0.001GlyXaa: 0.001 ± 0.0
His	1.359HisAla: 1.359 ± 0.009	0.754HisCys: 0.754 ± 0.007	0.972HisAsp: 0.972 ± 0.009	1.236HisGlu: 1.236 ± 0.009	1.07HisPhe: 1.07 ± 0.008	1.541HisGly: 1.541 ± 0.011	1.14HisHis: 1.14 ± 0.014	1.348HisIle: 1.348 ± 0.009	1.327HisLys: 1.327 ± 0.009	2.704HisLeu: 2.704 ± 0.013	0.671HisMet: 0.671 ± 0.006	1.051HisAsn: 1.051 ± 0.008	1.608HisPro: 1.608 ± 0.011	1.287HisGln: 1.287 ± 0.01	1.653HisArg: 1.653 ± 0.011	2.568HisSer: 2.568 ± 0.012	1.666HisThr: 1.666 ± 0.012	1.43HisVal: 1.43 ± 0.009	0.327HisTrp: 0.327 ± 0.004	0.864HisTyr: 0.864 ± 0.006	0.0HisXaa: 0.0 ± 0.0
Ile	2.55IleAla: 2.55 ± 0.012	1.104IleCys: 1.104 ± 0.009	2.123IleAsp: 2.123 ± 0.014	2.417IleGlu: 2.417 ± 0.012	1.861IlePhe: 1.861 ± 0.014	2.309IleGly: 2.309 ± 0.014	1.287IleHis: 1.287 ± 0.008	2.479IleIle: 2.479 ± 0.015	2.629IleLys: 2.629 ± 0.013	4.362IleLeu: 4.362 ± 0.021	1.08IleMet: 1.08 ± 0.007	1.992IleAsn: 1.992 ± 0.012	2.543IlePro: 2.543 ± 0.014	2.246IleGln: 2.246 ± 0.012	2.427IleArg: 2.427 ± 0.011	3.913IleSer: 3.913 ± 0.017	2.871IleThr: 2.871 ± 0.014	2.577IleVal: 2.577 ± 0.015	0.479IleTrp: 0.479 ± 0.005	1.427IleTyr: 1.427 ± 0.01	0.0IleXaa: 0.0 ± 0.0
Lys	3.774LysAla: 3.774 ± 0.017	1.054LysCys: 1.054 ± 0.01	3.3LysAsp: 3.3 ± 0.017	4.878LysGlu: 4.878 ± 0.029	1.616LysPhe: 1.616 ± 0.011	3.209LysGly: 3.209 ± 0.018	1.466LysHis: 1.466 ± 0.009	2.563LysIle: 2.563 ± 0.013	4.638LysLys: 4.638 ± 0.028	5.032LysLeu: 5.032 ± 0.022	1.488LysMet: 1.488 ± 0.009	2.382LysAsn: 2.382 ± 0.013	3.006LysPro: 3.006 ± 0.017	2.63LysGln: 2.63 ± 0.014	3.473LysArg: 3.473 ± 0.018	3.969LysSer: 3.969 ± 0.018	3.32LysThr: 3.32 ± 0.017	3.571LysVal: 3.571 ± 0.014	0.58LysTrp: 0.58 ± 0.006	1.519LysTyr: 1.519 ± 0.012	0.0LysXaa: 0.0 ± 0.0
Leu	5.921LeuAla: 5.921 ± 0.021	2.232LeuCys: 2.232 ± 0.013	4.771LeuAsp: 4.771 ± 0.02	6.384LeuGlu: 6.384 ± 0.032	3.465LeuPhe: 3.465 ± 0.019	5.067LeuGly: 5.067 ± 0.02	2.719LeuHis: 2.719 ± 0.015	3.871LeuIle: 3.871 ± 0.016	5.67LeuLys: 5.67 ± 0.026	9.852LeuLeu: 9.852 ± 0.037	2.107LeuMet: 2.107 ± 0.012	3.663LeuAsn: 3.663 ± 0.015	5.349LeuPro: 5.349 ± 0.021	5.389LeuGln: 5.389 ± 0.026	5.499LeuArg: 5.499 ± 0.023	8.381LeuSer: 8.381 ± 0.028	5.298LeuThr: 5.298 ± 0.017	5.336LeuVal: 5.336 ± 0.022	1.058LeuTrp: 1.058 ± 0.008	2.623LeuTyr: 2.623 ± 0.014	0.001LeuXaa: 0.001 ± 0.0
Met	1.909MetAla: 1.909 ± 0.011	0.487MetCys: 0.487 ± 0.005	1.415MetAsp: 1.415 ± 0.008	1.968MetGlu: 1.968 ± 0.012	0.85MetPhe: 0.85 ± 0.008	1.429MetGly: 1.429 ± 0.013	0.5MetHis: 0.5 ± 0.005	0.904MetIle: 0.904 ± 0.008	1.497MetLys: 1.497 ± 0.008	2.1MetLeu: 2.1 ± 0.012	0.711MetMet: 0.711 ± 0.008	0.936MetAsn: 0.936 ± 0.008	1.123MetPro: 1.123 ± 0.009	1.002MetGln: 1.002 ± 0.008	1.179MetArg: 1.179 ± 0.008	1.909MetSer: 1.909 ± 0.012	1.298MetThr: 1.298 ± 0.009	1.526MetVal: 1.526 ± 0.009	0.261MetTrp: 0.261 ± 0.004	0.636MetTyr: 0.636 ± 0.006	0.0MetXaa: 0.0 ± 0.0
Asn	2.187AsnAla: 2.187 ± 0.012	0.882AsnCys: 0.882 ± 0.008	1.735AsnAsp: 1.735 ± 0.011	2.144AsnGlu: 2.144 ± 0.012	1.441AsnPhe: 1.441 ± 0.01	2.824AsnGly: 2.824 ± 0.017	1.035AsnHis: 1.035 ± 0.008	2.2AsnIle: 2.2 ± 0.013	2.3AsnLys: 2.3 ± 0.011	3.683AsnLeu: 3.683 ± 0.017	1.057AsnMet: 1.057 ± 0.008	1.904AsnAsn: 1.904 ± 0.013	2.276AsnPro: 2.276 ± 0.012	1.769AsnGln: 1.769 ± 0.011	1.998AsnArg: 1.998 ± 0.01	3.396AsnSer: 3.396 ± 0.015	2.347AsnThr: 2.347 ± 0.013	2.314AsnVal: 2.314 ± 0.014	0.447AsnTrp: 0.447 ± 0.005	1.16AsnTyr: 1.16 ± 0.008	0.001AsnXaa: 0.001 ± 0.0
Pro	4.119ProAla: 4.119 ± 0.021	1.069ProCys: 1.069 ± 0.01	2.845ProAsp: 2.845 ± 0.014	3.728ProGlu: 3.728 ± 0.016	1.796ProPhe: 1.796 ± 0.012	3.961ProGly: 3.961 ± 0.036	1.534ProHis: 1.534 ± 0.012	1.94ProIle: 1.94 ± 0.011	2.623ProLys: 2.623 ± 0.015	4.86ProLeu: 4.86 ± 0.021	1.043ProMet: 1.043 ± 0.008	1.977ProAsn: 1.977 ± 0.014	5.545ProPro: 5.545 ± 0.039	2.728ProGln: 2.728 ± 0.018	2.725ProArg: 2.725 ± 0.013	5.719ProSer: 5.719 ± 0.028	3.177ProThr: 3.177 ± 0.017	3.789ProVal: 3.789 ± 0.016	0.535ProTrp: 0.535 ± 0.006	1.447ProTyr: 1.447 ± 0.01	0.001ProXaa: 0.001 ± 0.0
Gln	3.154GlnAla: 3.154 ± 0.017	0.973GlnCys: 0.973 ± 0.01	2.294GlnAsp: 2.294 ± 0.013	3.491GlnGlu: 3.491 ± 0.02	1.351GlnPhe: 1.351 ± 0.009	2.703GlnGly: 2.703 ± 0.015	1.398GlnHis: 1.398 ± 0.01	1.963GlnIle: 1.963 ± 0.009	2.679GlnLys: 2.679 ± 0.015	4.493GlnLeu: 4.493 ± 0.021	1.157GlnMet: 1.157 ± 0.008	1.802GlnAsn: 1.802 ± 0.009	2.636GlnPro: 2.636 ± 0.018	3.405GlnGln: 3.405 ± 0.033	3.068GlnArg: 3.068 ± 0.018	3.638GlnSer: 3.638 ± 0.016	2.619GlnThr: 2.619 ± 0.014	2.789GlnVal: 2.789 ± 0.014	0.538GlnTrp: 0.538 ± 0.005	1.258GlnTyr: 1.258 ± 0.009	0.001GlnXaa: 0.001 ± 0.0
Arg	3.337ArgAla: 3.337 ± 0.014	1.216ArgCys: 1.216 ± 0.011	2.907ArgAsp: 2.907 ± 0.015	3.91ArgGlu: 3.91 ± 0.02	1.935ArgPhe: 1.935 ± 0.011	3.377ArgGly: 3.377 ± 0.019	1.566ArgHis: 1.566 ± 0.011	2.377ArgIle: 2.377 ± 0.012	3.581ArgLys: 3.581 ± 0.017	5.176ArgLeu: 5.176 ± 0.022	1.298ArgMet: 1.298 ± 0.008	2.119ArgAsn: 2.119 ± 0.012	2.901ArgPro: 2.901 ± 0.016	2.66ArgGln: 2.66 ± 0.017	4.27ArgArg: 4.27 ± 0.024	4.551ArgSer: 4.551 ± 0.022	2.89ArgThr: 2.89 ± 0.013	3.237ArgVal: 3.237 ± 0.014	0.664ArgTrp: 0.664 ± 0.007	1.578ArgTyr: 1.578 ± 0.01	0.0ArgXaa: 0.0 ± 0.0
Ser	5.68SerAla: 5.68 ± 0.023	1.993SerCys: 1.993 ± 0.015	4.387SerAsp: 4.387 ± 0.018	5.034SerGlu: 5.034 ± 0.022	3.155SerPhe: 3.155 ± 0.014	5.616SerGly: 5.616 ± 0.02	2.337SerHis: 2.337 ± 0.012	3.457SerIle: 3.457 ± 0.015	4.17SerLys: 4.17 ± 0.02	8.428SerLeu: 8.428 ± 0.027	1.845SerMet: 1.845 ± 0.011	3.148SerAsn: 3.148 ± 0.014	6.123SerPro: 6.123 ± 0.031	4.05SerGln: 4.05 ± 0.018	4.508SerArg: 4.508 ± 0.02	10.773SerSer: 10.773 ± 0.058	5.035SerThr: 5.035 ± 0.022	5.483SerVal: 5.483 ± 0.02	0.999SerTrp: 0.999 ± 0.009	2.21SerTyr: 2.21 ± 0.013	0.001SerXaa: 0.001 ± 0.0
Thr	4.078ThrAla: 4.078 ± 0.017	1.366ThrCys: 1.366 ± 0.012	2.931ThrAsp: 2.931 ± 0.012	3.811ThrGlu: 3.811 ± 0.017	2.121ThrPhe: 2.121 ± 0.014	3.735ThrGly: 3.735 ± 0.016	1.468ThrHis: 1.468 ± 0.01	2.479ThrIle: 2.479 ± 0.014	2.78ThrLys: 2.78 ± 0.011	5.412ThrLeu: 5.412 ± 0.019	1.229ThrMet: 1.229 ± 0.008	2.03ThrAsn: 2.03 ± 0.012	3.733ThrPro: 3.733 ± 0.02	2.422ThrGln: 2.422 ± 0.013	2.51ThrArg: 2.51 ± 0.012	5.046ThrSer: 5.046 ± 0.018	3.494ThrThr: 3.494 ± 0.023	4.191ThrVal: 4.191 ± 0.019	0.661ThrTrp: 0.661 ± 0.007	1.465ThrTyr: 1.465 ± 0.01	0.001ThrXaa: 0.001 ± 0.0
Val	4.036ValAla: 4.036 ± 0.015	1.708ValCys: 1.708 ± 0.011	3.149ValAsp: 3.149 ± 0.014	4.021ValGlu: 4.021 ± 0.015	2.654ValPhe: 2.654 ± 0.014	3.462ValGly: 3.462 ± 0.016	1.571ValHis: 1.571 ± 0.009	3.066ValIle: 3.066 ± 0.017	3.626ValLys: 3.626 ± 0.015	6.037ValLeu: 6.037 ± 0.023	1.523ValMet: 1.523 ± 0.01	2.455ValAsn: 2.455 ± 0.013	3.283ValPro: 3.283 ± 0.013	2.735ValGln: 2.735 ± 0.012	3.184ValArg: 3.184 ± 0.015	5.342ValSer: 5.342 ± 0.019	4.029ValThr: 4.029 ± 0.018	4.302ValVal: 4.302 ± 0.02	0.752ValTrp: 0.752 ± 0.006	1.824ValTyr: 1.824 ± 0.011	0.001ValXaa: 0.001 ± 0.0
Trp	0.653TrpAla: 0.653 ± 0.006	0.246TrpCys: 0.246 ± 0.004	0.633TrpAsp: 0.633 ± 0.007	0.741TrpGlu: 0.741 ± 0.006	0.469TrpPhe: 0.469 ± 0.005	0.619TrpGly: 0.619 ± 0.008	0.274TrpHis: 0.274 ± 0.004	0.574TrpIle: 0.574 ± 0.006	0.723TrpLys: 0.723 ± 0.006	1.14TrpLeu: 1.14 ± 0.009	0.336TrpMet: 0.336 ± 0.004	0.513TrpAsn: 0.513 ± 0.006	0.427TrpPro: 0.427 ± 0.004	0.483TrpGln: 0.483 ± 0.005	0.707TrpArg: 0.707 ± 0.007	0.947TrpSer: 0.947 ± 0.007	0.677TrpThr: 0.677 ± 0.007	0.685TrpVal: 0.685 ± 0.006	0.19TrpTrp: 0.19 ± 0.004	0.349TrpTyr: 0.349 ± 0.004	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.426TyrAla: 1.426 ± 0.01	0.739TyrCys: 0.739 ± 0.007	1.377TyrAsp: 1.377 ± 0.01	1.585TyrGlu: 1.585 ± 0.01	1.227TyrPhe: 1.227 ± 0.01	1.678TyrGly: 1.678 ± 0.011	0.805TyrHis: 0.805 ± 0.007	1.507TyrIle: 1.507 ± 0.011	1.501TyrLys: 1.501 ± 0.01	2.632TyrLeu: 2.632 ± 0.013	0.677TyrMet: 0.677 ± 0.006	1.238TyrAsn: 1.238 ± 0.008	1.345TyrPro: 1.345 ± 0.009	1.262TyrGln: 1.262 ± 0.009	1.689TyrArg: 1.689 ± 0.01	2.409TyrSer: 2.409 ± 0.013	1.677TyrThr: 1.677 ± 0.012	1.575TyrVal: 1.575 ± 0.01	0.387TyrTrp: 0.387 ± 0.006	1.017TyrTyr: 1.017 ± 0.009	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.001XaaCys: 0.001 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.001XaaGlu: 0.001 ± 0.0	0.001XaaPhe: 0.001 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.001XaaLeu: 0.001 ± 0.0	0.002XaaMet: 0.002 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.001XaaSer: 0.001 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.001XaaVal: 0.001 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.409XaaXaa: 0.409 ± 0.066

Statistics based on 34332 proteins (19812588 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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