Amino acid dipepetide frequency for Cotton leaf curl Burewala virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.24AlaAla: 7.24 ± 2.591
0.905AlaCys: 0.905 ± 0.763
0.905AlaAsp: 0.905 ± 0.763
0.905AlaGlu: 0.905 ± 0.904
0.0AlaPhe: 0.0 ± 0.0
3.62AlaGly: 3.62 ± 1.281
3.62AlaHis: 3.62 ± 1.89
2.715AlaIle: 2.715 ± 1.367
1.81AlaLys: 1.81 ± 0.648
8.145AlaLeu: 8.145 ± 1.633
0.0AlaMet: 0.0 ± 0.0
3.62AlaAsn: 3.62 ± 0.932
3.62AlaPro: 3.62 ± 1.581
5.43AlaGln: 5.43 ± 1.683
5.43AlaArg: 5.43 ± 2.514
2.715AlaSer: 2.715 ± 2.289
3.62AlaThr: 3.62 ± 2.394
3.62AlaVal: 3.62 ± 1.415
1.81AlaTrp: 1.81 ± 0.648
2.715AlaTyr: 2.715 ± 1.492
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.81CysCys: 1.81 ± 2.409
0.0CysAsp: 0.0 ± 0.0
1.81CysGlu: 1.81 ± 1.309
0.905CysPhe: 0.905 ± 0.948
0.905CysGly: 0.905 ± 0.633
0.0CysHis: 0.0 ± 0.0
0.905CysIle: 0.905 ± 0.904
0.905CysLys: 0.905 ± 0.763
0.0CysLeu: 0.0 ± 0.0
0.905CysMet: 0.905 ± 1.205
0.905CysAsn: 0.905 ± 0.633
1.81CysPro: 1.81 ± 2.409
0.0CysGln: 0.0 ± 0.0
0.905CysArg: 0.905 ± 0.633
2.715CysSer: 2.715 ± 1.302
1.81CysThr: 1.81 ± 0.648
1.81CysVal: 1.81 ± 1.526
0.0CysTrp: 0.0 ± 0.0
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.715AspAla: 2.715 ± 1.899
0.0AspCys: 0.0 ± 0.0
0.905AspAsp: 0.905 ± 0.633
1.81AspGlu: 1.81 ± 0.648
1.81AspPhe: 1.81 ± 0.648
2.715AspGly: 2.715 ± 1.899
0.0AspHis: 0.0 ± 0.0
2.715AspIle: 2.715 ± 1.737
1.81AspLys: 1.81 ± 0.648
3.62AspLeu: 3.62 ± 2.409
0.0AspMet: 0.0 ± 0.0
1.81AspAsn: 1.81 ± 0.648
1.81AspPro: 1.81 ± 1.204
4.525AspGln: 4.525 ± 2.454
3.62AspArg: 3.62 ± 1.296
5.43AspSer: 5.43 ± 1.609
3.62AspThr: 3.62 ± 2.331
5.43AspVal: 5.43 ± 2.144
0.905AspTrp: 0.905 ± 0.633
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
4.525GluAla: 4.525 ± 1.558
0.0GluCys: 0.0 ± 0.0
2.715GluAsp: 2.715 ± 1.719
6.335GluGlu: 6.335 ± 3.62
3.62GluPhe: 3.62 ± 1.963
3.62GluGly: 3.62 ± 1.178
0.905GluHis: 0.905 ± 0.948
0.905GluIle: 0.905 ± 0.948
1.81GluLys: 1.81 ± 1.204
3.62GluLeu: 3.62 ± 1.831
0.0GluMet: 0.0 ± 0.0
2.715GluAsn: 2.715 ± 2.289
3.62GluPro: 3.62 ± 1.114
2.715GluGln: 2.715 ± 2.397
0.0GluArg: 0.0 ± 0.0
4.525GluSer: 4.525 ± 2.413
0.0GluThr: 0.0 ± 0.0
2.715GluVal: 2.715 ± 1.037
0.905GluTrp: 0.905 ± 0.633
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
0.905PheCys: 0.905 ± 0.763
3.62PheAsp: 3.62 ± 1.296
2.715PheGlu: 2.715 ± 1.072
1.81PhePhe: 1.81 ± 0.648
1.81PheGly: 1.81 ± 1.052
2.715PheHis: 2.715 ± 1.501
3.62PheIle: 3.62 ± 1.581
6.335PheLys: 6.335 ± 2.67
4.525PheLeu: 4.525 ± 1.973
0.905PheMet: 0.905 ± 0.633
1.81PheAsn: 1.81 ± 1.173
1.81PhePro: 1.81 ± 1.433
1.81PheGln: 1.81 ± 1.266
3.62PheArg: 3.62 ± 1.917
0.905PheSer: 0.905 ± 0.633
0.905PheThr: 0.905 ± 0.948
1.81PheVal: 1.81 ± 1.266
0.0PheTrp: 0.0 ± 0.0
0.905PheTyr: 0.905 ± 0.763
0.0PheXaa: 0.0 ± 0.0
Gly
2.715GlyAla: 2.715 ± 1.072
0.905GlyCys: 0.905 ± 0.763
2.715GlyAsp: 2.715 ± 1.306
4.525GlyGlu: 4.525 ± 0.848
0.905GlyPhe: 0.905 ± 1.205
2.715GlyGly: 2.715 ± 1.029
0.905GlyHis: 0.905 ± 0.633
0.905GlyIle: 0.905 ± 0.633
6.335GlyLys: 6.335 ± 2.482
2.715GlyLeu: 2.715 ± 1.992
0.0GlyMet: 0.0 ± 0.0
1.81GlyAsn: 1.81 ± 1.25
3.62GlyPro: 3.62 ± 1.238
1.81GlyGln: 1.81 ± 0.648
0.905GlyArg: 0.905 ± 0.633
2.715GlySer: 2.715 ± 1.367
5.43GlyThr: 5.43 ± 1.188
1.81GlyVal: 1.81 ± 1.078
0.0GlyTrp: 0.0 ± 0.0
1.81GlyTyr: 1.81 ± 1.525
0.0GlyXaa: 0.0 ± 0.0
His
1.81HisAla: 1.81 ± 1.309
0.905HisCys: 0.905 ± 1.205
0.905HisAsp: 0.905 ± 0.763
1.81HisGlu: 1.81 ± 1.204
4.525HisPhe: 4.525 ± 1.84
0.905HisGly: 0.905 ± 1.205
0.0HisHis: 0.0 ± 0.0
1.81HisIle: 1.81 ± 1.052
0.905HisLys: 0.905 ± 0.948
2.715HisLeu: 2.715 ± 1.306
0.0HisMet: 0.0 ± 0.0
1.81HisAsn: 1.81 ± 1.266
1.81HisPro: 1.81 ± 0.928
1.81HisGln: 1.81 ± 1.433
1.81HisArg: 1.81 ± 1.526
1.81HisSer: 1.81 ± 1.807
1.81HisThr: 1.81 ± 1.526
2.715HisVal: 2.715 ± 1.929
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
0.0IleAla: 0.0 ± 0.0
0.905IleCys: 0.905 ± 1.205
5.43IleAsp: 5.43 ± 3.008
0.905IleGlu: 0.905 ± 0.633
2.715IlePhe: 2.715 ± 1.899
0.905IleGly: 0.905 ± 0.763
0.905IleHis: 0.905 ± 0.904
3.62IleIle: 3.62 ± 1.666
8.145IleLys: 8.145 ± 2.559
2.715IleLeu: 2.715 ± 1.564
0.0IleMet: 0.0 ± 0.0
2.715IleAsn: 2.715 ± 1.072
1.81IlePro: 1.81 ± 0.928
6.335IleGln: 6.335 ± 1.888
4.525IleArg: 4.525 ± 2.58
7.24IleSer: 7.24 ± 2.512
3.62IleThr: 3.62 ± 1.362
1.81IleVal: 1.81 ± 0.648
2.715IleTrp: 2.715 ± 1.992
0.905IleTyr: 0.905 ± 0.763
0.0IleXaa: 0.0 ± 0.0
Lys
7.24LysAla: 7.24 ± 1.735
0.905LysCys: 0.905 ± 0.948
1.81LysAsp: 1.81 ± 1.266
4.525LysGlu: 4.525 ± 2.177
3.62LysPhe: 3.62 ± 0.877
1.81LysGly: 1.81 ± 0.986
1.81LysHis: 1.81 ± 0.928
4.525LysIle: 4.525 ± 2.188
1.81LysLys: 1.81 ± 0.648
2.715LysLeu: 2.715 ± 1.232
0.905LysMet: 0.905 ± 0.904
7.24LysAsn: 7.24 ± 1.751
4.525LysPro: 4.525 ± 1.728
0.0LysGln: 0.0 ± 0.0
3.62LysArg: 3.62 ± 1.215
5.43LysSer: 5.43 ± 2.256
3.62LysThr: 3.62 ± 1.114
4.525LysVal: 4.525 ± 1.861
0.905LysTrp: 0.905 ± 0.763
5.43LysTyr: 5.43 ± 0.681
0.0LysXaa: 0.0 ± 0.0
Leu
1.81LeuAla: 1.81 ± 1.204
2.715LeuCys: 2.715 ± 1.899
2.715LeuAsp: 2.715 ± 1.899
2.715LeuGlu: 2.715 ± 1.306
0.905LeuPhe: 0.905 ± 0.948
4.525LeuGly: 4.525 ± 1.769
2.715LeuHis: 2.715 ± 1.492
5.43LeuIle: 5.43 ± 3.224
7.24LeuLys: 7.24 ± 1.996
1.81LeuLeu: 1.81 ± 1.433
0.905LeuMet: 0.905 ± 0.763
5.43LeuAsn: 5.43 ± 0.681
0.905LeuPro: 0.905 ± 0.904
2.715LeuGln: 2.715 ± 1.284
5.43LeuArg: 5.43 ± 0.681
4.525LeuSer: 4.525 ± 2.61
5.43LeuThr: 5.43 ± 1.898
6.335LeuVal: 6.335 ± 2.349
0.0LeuTrp: 0.0 ± 0.0
3.62LeuTyr: 3.62 ± 1.879
0.0LeuXaa: 0.0 ± 0.0
Met
1.81MetAla: 1.81 ± 0.648
1.81MetCys: 1.81 ± 1.052
2.715MetAsp: 2.715 ± 1.992
0.905MetGlu: 0.905 ± 0.904
1.81MetPhe: 1.81 ± 1.526
2.715MetGly: 2.715 ± 1.302
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
1.81MetLeu: 1.81 ± 1.309
0.0MetMet: 0.0 ± 0.0
0.905MetAsn: 0.905 ± 0.763
0.905MetPro: 0.905 ± 0.904
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.81MetSer: 1.81 ± 1.052
0.905MetThr: 0.905 ± 0.937
0.0MetVal: 0.0 ± 0.0
1.81MetTrp: 1.81 ± 1.204
2.715MetTyr: 2.715 ± 1.737
0.0MetXaa: 0.0 ± 0.0
Asn
3.62AsnAla: 3.62 ± 1.581
0.905AsnCys: 0.905 ± 0.904
1.81AsnAsp: 1.81 ± 1.266
1.81AsnGlu: 1.81 ± 1.309
0.905AsnPhe: 0.905 ± 0.763
0.905AsnGly: 0.905 ± 0.948
2.715AsnHis: 2.715 ± 1.772
1.81AsnIle: 1.81 ± 0.648
0.905AsnLys: 0.905 ± 0.633
3.62AsnLeu: 3.62 ± 2.156
2.715AsnMet: 2.715 ± 1.591
2.715AsnAsn: 2.715 ± 1.037
3.62AsnPro: 3.62 ± 1.281
2.715AsnGln: 2.715 ± 0.766
3.62AsnArg: 3.62 ± 1.467
4.525AsnSer: 4.525 ± 1.755
5.43AsnThr: 5.43 ± 1.751
4.525AsnVal: 4.525 ± 0.956
0.905AsnTrp: 0.905 ± 0.633
4.525AsnTyr: 4.525 ± 1.158
0.0AsnXaa: 0.0 ± 0.0
Pro
2.715ProAla: 2.715 ± 1.266
1.81ProCys: 1.81 ± 1.309
3.62ProAsp: 3.62 ± 2.417
0.905ProGlu: 0.905 ± 0.633
2.715ProPhe: 2.715 ± 1.072
0.905ProGly: 0.905 ± 0.633
3.62ProHis: 3.62 ± 1.963
3.62ProIle: 3.62 ± 1.333
5.43ProLys: 5.43 ± 2.146
2.715ProLeu: 2.715 ± 1.501
0.905ProMet: 0.905 ± 0.763
3.62ProAsn: 3.62 ± 1.362
3.62ProPro: 3.62 ± 1.191
4.525ProGln: 4.525 ± 1.448
5.43ProArg: 5.43 ± 1.722
4.525ProSer: 4.525 ± 0.991
4.525ProThr: 4.525 ± 1.903
2.715ProVal: 2.715 ± 1.266
0.0ProTrp: 0.0 ± 0.0
2.715ProTyr: 2.715 ± 1.037
0.0ProXaa: 0.0 ± 0.0
Gln
6.335GlnAla: 6.335 ± 1.104
0.905GlnCys: 0.905 ± 0.633
2.715GlnAsp: 2.715 ± 2.397
3.62GlnGlu: 3.62 ± 0.932
3.62GlnPhe: 3.62 ± 1.509
1.81GlnGly: 1.81 ± 1.266
2.715GlnHis: 2.715 ± 1.807
2.715GlnIle: 2.715 ± 1.899
1.81GlnLys: 1.81 ± 2.409
2.715GlnLeu: 2.715 ± 2.488
0.905GlnMet: 0.905 ± 0.904
0.0GlnAsn: 0.0 ± 0.0
3.62GlnPro: 3.62 ± 1.917
5.43GlnGln: 5.43 ± 1.063
1.81GlnArg: 1.81 ± 0.928
7.24GlnSer: 7.24 ± 2.177
3.62GlnThr: 3.62 ± 1.965
2.715GlnVal: 2.715 ± 1.037
0.905GlnTrp: 0.905 ± 0.904
1.81GlnTyr: 1.81 ± 1.173
0.0GlnXaa: 0.0 ± 0.0
Arg
2.715ArgAla: 2.715 ± 1.422
1.81ArgCys: 1.81 ± 2.409
3.62ArgAsp: 3.62 ± 1.419
1.81ArgGlu: 1.81 ± 0.928
3.62ArgPhe: 3.62 ± 1.178
2.715ArgGly: 2.715 ± 1.266
1.81ArgHis: 1.81 ± 1.309
5.43ArgIle: 5.43 ± 1.605
3.62ArgLys: 3.62 ± 1.666
1.81ArgLeu: 1.81 ± 1.052
1.81ArgMet: 1.81 ± 1.526
1.81ArgAsn: 1.81 ± 1.433
7.24ArgPro: 7.24 ± 1.53
1.81ArgGln: 1.81 ± 1.433
2.715ArgArg: 2.715 ± 2.289
6.335ArgSer: 6.335 ± 2.554
3.62ArgThr: 3.62 ± 1.664
5.43ArgVal: 5.43 ± 1.872
0.0ArgTrp: 0.0 ± 0.0
1.81ArgTyr: 1.81 ± 1.309
0.0ArgXaa: 0.0 ± 0.0
Ser
5.43SerAla: 5.43 ± 2.636
0.0SerCys: 0.0 ± 0.0
1.81SerAsp: 1.81 ± 0.648
2.715SerGlu: 2.715 ± 1.492
2.715SerPhe: 2.715 ± 0.766
1.81SerGly: 1.81 ± 0.928
0.905SerHis: 0.905 ± 0.948
2.715SerIle: 2.715 ± 1.072
3.62SerLys: 3.62 ± 2.394
5.43SerLeu: 5.43 ± 3.437
5.43SerMet: 5.43 ± 2.597
5.43SerAsn: 5.43 ± 1.441
8.145SerPro: 8.145 ± 1.937
4.525SerGln: 4.525 ± 2.014
9.05SerArg: 9.05 ± 2.151
13.575SerSer: 13.575 ± 6.661
7.24SerThr: 7.24 ± 3.099
2.715SerVal: 2.715 ± 2.289
0.905SerTrp: 0.905 ± 0.937
1.81SerTyr: 1.81 ± 0.928
0.0SerXaa: 0.0 ± 0.0
Thr
5.43ThrAla: 5.43 ± 1.683
0.0ThrCys: 0.0 ± 0.0
0.905ThrAsp: 0.905 ± 0.904
0.905ThrGlu: 0.905 ± 0.763
1.81ThrPhe: 1.81 ± 1.115
7.24ThrGly: 7.24 ± 2.493
2.715ThrHis: 2.715 ± 1.6
2.715ThrIle: 2.715 ± 1.072
5.43ThrLys: 5.43 ± 1.31
7.24ThrLeu: 7.24 ± 1.178
1.81ThrMet: 1.81 ± 1.078
4.525ThrAsn: 4.525 ± 1.446
3.62ThrPro: 3.62 ± 1.05
2.715ThrGln: 2.715 ± 1.364
4.525ThrArg: 4.525 ± 1.136
3.62ThrSer: 3.62 ± 2.253
2.715ThrThr: 2.715 ± 1.862
2.715ThrVal: 2.715 ± 1.772
0.905ThrTrp: 0.905 ± 0.904
1.81ThrTyr: 1.81 ± 1.204
0.0ThrXaa: 0.0 ± 0.0
Val
0.0ValAla: 0.0 ± 0.0
0.905ValCys: 0.905 ± 0.633
3.62ValAsp: 3.62 ± 1.256
2.715ValGlu: 2.715 ± 2.361
1.81ValPhe: 1.81 ± 1.173
0.905ValGly: 0.905 ± 0.763
1.81ValHis: 1.81 ± 1.309
8.145ValIle: 8.145 ± 3.164
7.24ValLys: 7.24 ± 1.311
6.335ValLeu: 6.335 ± 1.695
1.81ValMet: 1.81 ± 1.526
1.81ValAsn: 1.81 ± 1.173
2.715ValPro: 2.715 ± 1.037
5.43ValGln: 5.43 ± 2.256
2.715ValArg: 2.715 ± 2.289
2.715ValSer: 2.715 ± 1.266
3.62ValThr: 3.62 ± 3.052
1.81ValVal: 1.81 ± 0.648
0.905ValTrp: 0.905 ± 0.633
3.62ValTyr: 3.62 ± 1.987
0.0ValXaa: 0.0 ± 0.0
Trp
2.715TrpAla: 2.715 ± 1.029
0.0TrpCys: 0.0 ± 0.0
0.905TrpAsp: 0.905 ± 1.205
0.905TrpGlu: 0.905 ± 0.948
0.0TrpPhe: 0.0 ± 0.0
1.81TrpGly: 1.81 ± 0.986
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.905TrpLeu: 0.905 ± 0.904
0.905TrpMet: 0.905 ± 0.763
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.905TrpGln: 0.905 ± 0.633
0.0TrpArg: 0.0 ± 0.0
0.0TrpSer: 0.0 ± 0.0
0.905TrpThr: 0.905 ± 0.948
0.905TrpVal: 0.905 ± 0.633
0.0TrpTrp: 0.0 ± 0.0
2.715TrpTyr: 2.715 ± 0.766
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.62TyrAla: 3.62 ± 1.987
0.0TyrCys: 0.0 ± 0.0
1.81TyrAsp: 1.81 ± 1.309
0.905TyrGlu: 0.905 ± 0.763
2.715TyrPhe: 2.715 ± 1.037
0.905TyrGly: 0.905 ± 0.633
0.0TyrHis: 0.0 ± 0.0
3.62TyrIle: 3.62 ± 2.023
1.81TyrLys: 1.81 ± 0.928
2.715TyrLeu: 2.715 ± 1.284
1.81TyrMet: 1.81 ± 1.089
4.525TyrAsn: 4.525 ± 1.769
1.81TyrPro: 1.81 ± 0.928
1.81TyrGln: 1.81 ± 1.292
1.81TyrArg: 1.81 ± 1.526
3.62TyrSer: 3.62 ± 1.52
0.905TyrThr: 0.905 ± 0.904
4.525TyrVal: 4.525 ± 2.397
0.0TyrTrp: 0.0 ± 0.0
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (1106 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski