Amino acid dipepetide frequency for Beihai sipunculid worm virus 3

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.387AlaAla: 7.387 ± 1.402
0.778AlaCys: 0.778 ± 0.134
5.443AlaAsp: 5.443 ± 0.342
6.221AlaGlu: 6.221 ± 1.899
4.666AlaPhe: 4.666 ± 1.573
5.832AlaGly: 5.832 ± 0.112
2.333AlaHis: 2.333 ± 0.193
5.054AlaIle: 5.054 ± 1.803
3.888AlaLys: 3.888 ± 0.519
6.61AlaLeu: 6.61 ± 2.129
1.166AlaMet: 1.166 ± 0.497
3.11AlaAsn: 3.11 ± 0.535
3.11AlaPro: 3.11 ± 0.059
0.778AlaGln: 0.778 ± 0.134
3.11AlaArg: 3.11 ± 0.059
3.888AlaSer: 3.888 ± 0.668
3.888AlaThr: 3.888 ± 0.075
4.666AlaVal: 4.666 ± 1.396
0.0AlaTrp: 0.0 ± 0.0
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
1.166CysAla: 1.166 ± 0.69
0.0CysCys: 0.0 ± 0.0
0.778CysAsp: 0.778 ± 0.134
1.166CysGlu: 1.166 ± 0.69
1.555CysPhe: 1.555 ± 0.92
1.166CysGly: 1.166 ± 0.096
0.0CysHis: 0.0 ± 0.0
0.389CysIle: 0.389 ± 0.23
0.778CysLys: 0.778 ± 0.46
0.778CysLeu: 0.778 ± 0.46
0.389CysMet: 0.389 ± 0.364
1.166CysAsn: 1.166 ± 0.096
0.389CysPro: 0.389 ± 0.23
0.389CysGln: 0.389 ± 0.23
0.389CysArg: 0.389 ± 0.364
0.389CysSer: 0.389 ± 0.23
0.778CysThr: 0.778 ± 0.46
0.778CysVal: 0.778 ± 0.46
0.0CysTrp: 0.0 ± 0.0
1.166CysTyr: 1.166 ± 0.497
0.0CysXaa: 0.0 ± 0.0
Asp
6.998AspAla: 6.998 ± 0.609
0.0AspCys: 0.0 ± 0.0
5.054AspAsp: 5.054 ± 1.166
4.666AspGlu: 4.666 ± 0.802
3.888AspPhe: 3.888 ± 0.519
4.277AspGly: 4.277 ± 0.155
1.944AspHis: 1.944 ± 0.556
2.333AspIle: 2.333 ± 0.995
3.888AspLys: 3.888 ± 0.075
5.054AspLeu: 5.054 ± 1.803
0.389AspMet: 0.389 ± 0.364
0.778AspAsn: 0.778 ± 0.134
3.11AspPro: 3.11 ± 1.722
0.778AspGln: 0.778 ± 0.134
1.944AspArg: 1.944 ± 0.037
3.11AspSer: 3.11 ± 0.535
3.11AspThr: 3.11 ± 1.128
4.666AspVal: 4.666 ± 1.396
0.389AspTrp: 0.389 ± 0.364
2.333AspTyr: 2.333 ± 0.786
0.0AspXaa: 0.0 ± 0.0
Glu
4.277GluAla: 4.277 ± 1.343
2.722GluCys: 2.722 ± 1.016
4.277GluAsp: 4.277 ± 1.032
4.277GluGlu: 4.277 ± 0.749
3.11GluPhe: 3.11 ± 1.246
2.333GluGly: 2.333 ± 0.193
0.778GluHis: 0.778 ± 0.46
2.722GluIle: 2.722 ± 0.171
4.277GluLys: 4.277 ± 0.749
5.443GluLeu: 5.443 ± 0.252
1.944GluMet: 1.944 ± 0.556
2.333GluAsn: 2.333 ± 0.786
2.722GluPro: 2.722 ± 0.765
1.944GluGln: 1.944 ± 0.631
3.499GluArg: 3.499 ± 0.883
5.054GluSer: 5.054 ± 1.166
2.333GluThr: 2.333 ± 0.786
3.11GluVal: 3.11 ± 0.059
0.389GluTrp: 0.389 ± 0.23
3.499GluTyr: 3.499 ± 0.305
0.0GluXaa: 0.0 ± 0.0
Phe
3.888PheAla: 3.888 ± 1.113
0.778PheCys: 0.778 ± 0.46
5.054PheAsp: 5.054 ± 1.803
3.888PheGlu: 3.888 ± 1.113
2.333PhePhe: 2.333 ± 0.193
5.054PheGly: 5.054 ± 1.209
0.778PheHis: 0.778 ± 0.134
3.499PheIle: 3.499 ± 1.476
3.888PheLys: 3.888 ± 1.113
2.722PheLeu: 2.722 ± 0.171
1.555PheMet: 1.555 ± 0.326
1.944PheAsn: 1.944 ± 0.037
3.499PhePro: 3.499 ± 0.305
1.555PheGln: 1.555 ± 0.267
1.944PheArg: 1.944 ± 0.631
1.555PheSer: 1.555 ± 0.267
2.722PheThr: 2.722 ± 0.765
1.555PheVal: 1.555 ± 0.267
1.944PheTrp: 1.944 ± 0.631
1.166PheTyr: 1.166 ± 0.497
0.0PheXaa: 0.0 ± 0.0
Gly
2.333GlyAla: 2.333 ± 0.995
0.0GlyCys: 0.0 ± 0.0
4.277GlyAsp: 4.277 ± 1.032
3.499GlyGlu: 3.499 ± 1.492
1.944GlyPhe: 1.944 ± 0.556
2.333GlyGly: 2.333 ± 0.401
1.166GlyHis: 1.166 ± 0.69
7.776GlyIle: 7.776 ± 0.149
5.443GlyLys: 5.443 ± 0.845
3.499GlyLeu: 3.499 ± 0.289
2.333GlyMet: 2.333 ± 0.193
6.61GlyAsn: 6.61 ± 2.026
1.166GlyPro: 1.166 ± 0.096
1.555GlyGln: 1.555 ± 0.861
2.722GlyArg: 2.722 ± 1.016
6.221GlySer: 6.221 ± 0.712
4.666GlyThr: 4.666 ± 0.208
5.443GlyVal: 5.443 ± 0.845
2.333GlyTrp: 2.333 ± 0.995
0.389GlyTyr: 0.389 ± 0.23
0.0GlyXaa: 0.0 ± 0.0
His
1.944HisAla: 1.944 ± 0.037
0.0HisCys: 0.0 ± 0.0
1.166HisAsp: 1.166 ± 0.096
1.555HisGlu: 1.555 ± 0.326
1.166HisPhe: 1.166 ± 0.096
1.944HisGly: 1.944 ± 0.556
1.166HisHis: 1.166 ± 0.69
1.166HisIle: 1.166 ± 0.69
0.778HisLys: 0.778 ± 0.727
0.778HisLeu: 0.778 ± 0.134
0.778HisMet: 0.778 ± 0.134
1.166HisAsn: 1.166 ± 0.096
2.333HisPro: 2.333 ± 0.193
0.389HisGln: 0.389 ± 0.23
0.389HisArg: 0.389 ± 0.364
1.944HisSer: 1.944 ± 0.631
1.166HisThr: 1.166 ± 0.096
1.555HisVal: 1.555 ± 0.92
0.389HisTrp: 0.389 ± 0.23
2.333HisTyr: 2.333 ± 0.995
0.0HisXaa: 0.0 ± 0.0
Ile
6.61IleAla: 6.61 ± 0.348
0.389IleCys: 0.389 ± 0.23
2.333IleAsp: 2.333 ± 0.401
4.277IleGlu: 4.277 ± 0.749
3.888IlePhe: 3.888 ± 0.668
1.555IleGly: 1.555 ± 0.861
1.555IleHis: 1.555 ± 0.267
1.944IleIle: 1.944 ± 0.037
2.333IleLys: 2.333 ± 0.786
2.722IleLeu: 2.722 ± 1.016
1.555IleMet: 1.555 ± 0.92
2.333IleAsn: 2.333 ± 0.401
2.333IlePro: 2.333 ± 0.786
1.555IleGln: 1.555 ± 0.326
2.333IleArg: 2.333 ± 0.193
5.443IleSer: 5.443 ± 0.342
5.832IleThr: 5.832 ± 0.705
5.443IleVal: 5.443 ± 0.252
0.389IleTrp: 0.389 ± 0.23
1.166IleTyr: 1.166 ± 0.69
0.0IleXaa: 0.0 ± 0.0
Lys
3.499LysAla: 3.499 ± 0.883
0.389LysCys: 0.389 ± 0.23
1.555LysAsp: 1.555 ± 0.92
4.277LysGlu: 4.277 ± 1.343
2.722LysPhe: 2.722 ± 0.171
5.054LysGly: 5.054 ± 0.615
1.166LysHis: 1.166 ± 0.096
2.722LysIle: 2.722 ± 0.171
3.11LysLys: 3.11 ± 1.84
7.387LysLeu: 7.387 ± 0.215
2.333LysMet: 2.333 ± 0.786
2.333LysAsn: 2.333 ± 0.193
2.722LysPro: 2.722 ± 0.765
1.944LysGln: 1.944 ± 0.037
2.722LysArg: 2.722 ± 0.423
4.277LysSer: 4.277 ± 1.343
3.888LysThr: 3.888 ± 1.113
3.11LysVal: 3.11 ± 0.059
0.778LysTrp: 0.778 ± 0.46
3.11LysTyr: 3.11 ± 1.246
0.0LysXaa: 0.0 ± 0.0
Leu
7.387LeuAla: 7.387 ± 1.996
2.333LeuCys: 2.333 ± 1.38
5.054LeuAsp: 5.054 ± 0.022
7.387LeuGlu: 7.387 ± 1.566
5.054LeuPhe: 5.054 ± 0.615
3.499LeuGly: 3.499 ± 0.898
2.333LeuHis: 2.333 ± 0.995
3.11LeuIle: 3.11 ± 1.246
4.277LeuLys: 4.277 ± 1.343
5.832LeuLeu: 5.832 ± 0.482
3.499LeuMet: 3.499 ± 1.476
3.888LeuAsn: 3.888 ± 1.856
2.722LeuPro: 2.722 ± 0.423
1.944LeuGln: 1.944 ± 1.225
4.277LeuArg: 4.277 ± 0.749
5.054LeuSer: 5.054 ± 0.615
5.832LeuThr: 5.832 ± 0.112
4.277LeuVal: 4.277 ± 0.749
2.333LeuTrp: 2.333 ± 0.193
1.944LeuTyr: 1.944 ± 1.15
0.0LeuXaa: 0.0 ± 0.0
Met
0.778MetAla: 0.778 ± 0.134
1.944MetCys: 1.944 ± 0.037
0.389MetAsp: 0.389 ± 0.364
1.555MetGlu: 1.555 ± 0.267
0.389MetPhe: 0.389 ± 0.23
1.944MetGly: 1.944 ± 0.631
0.0MetHis: 0.0 ± 0.0
2.333MetIle: 2.333 ± 0.401
1.944MetLys: 1.944 ± 0.556
2.333MetLeu: 2.333 ± 0.786
0.0MetMet: 0.0 ± 0.0
2.333MetAsn: 2.333 ± 0.786
1.555MetPro: 1.555 ± 0.861
1.166MetGln: 1.166 ± 0.497
1.166MetArg: 1.166 ± 0.69
3.499MetSer: 3.499 ± 1.476
1.555MetThr: 1.555 ± 0.92
0.778MetVal: 0.778 ± 0.134
0.389MetTrp: 0.389 ± 0.23
0.389MetTyr: 0.389 ± 0.23
0.0MetXaa: 0.0 ± 0.0
Asn
2.333AsnAla: 2.333 ± 0.786
1.166AsnCys: 1.166 ± 0.096
1.555AsnAsp: 1.555 ± 0.861
1.166AsnGlu: 1.166 ± 0.497
2.333AsnPhe: 2.333 ± 0.995
3.888AsnGly: 3.888 ± 0.519
1.166AsnHis: 1.166 ± 0.69
3.499AsnIle: 3.499 ± 0.289
0.778AsnLys: 0.778 ± 0.134
5.443AsnLeu: 5.443 ± 2.123
0.389AsnMet: 0.389 ± 0.23
3.499AsnAsn: 3.499 ± 0.898
3.499AsnPro: 3.499 ± 0.305
2.333AsnGln: 2.333 ± 1.588
1.555AsnArg: 1.555 ± 0.326
4.277AsnSer: 4.277 ± 0.438
2.722AsnThr: 2.722 ± 0.171
4.666AsnVal: 4.666 ± 0.802
1.555AsnTrp: 1.555 ± 0.267
3.11AsnTyr: 3.11 ± 2.316
0.0AsnXaa: 0.0 ± 0.0
Pro
2.722ProAla: 2.722 ± 1.358
0.778ProCys: 0.778 ± 0.134
2.333ProAsp: 2.333 ± 0.995
3.888ProGlu: 3.888 ± 1.706
2.722ProPhe: 2.722 ± 1.358
2.722ProGly: 2.722 ± 0.171
1.555ProHis: 1.555 ± 0.267
1.555ProIle: 1.555 ± 0.267
1.555ProLys: 1.555 ± 0.326
5.054ProLeu: 5.054 ± 0.572
2.333ProMet: 2.333 ± 0.401
1.166ProAsn: 1.166 ± 0.497
1.944ProPro: 1.944 ± 1.225
1.944ProGln: 1.944 ± 0.037
1.944ProArg: 1.944 ± 0.037
2.722ProSer: 2.722 ± 0.423
2.333ProThr: 2.333 ± 1.588
4.666ProVal: 4.666 ± 0.385
0.389ProTrp: 0.389 ± 0.364
1.944ProTyr: 1.944 ± 0.631
0.0ProXaa: 0.0 ± 0.0
Gln
3.499GlnAla: 3.499 ± 0.305
0.389GlnCys: 0.389 ± 0.364
0.778GlnAsp: 0.778 ± 0.727
0.389GlnGlu: 0.389 ± 0.364
1.166GlnPhe: 1.166 ± 0.096
1.555GlnGly: 1.555 ± 1.455
0.778GlnHis: 0.778 ± 0.134
1.944GlnIle: 1.944 ± 1.225
1.944GlnLys: 1.944 ± 1.15
3.499GlnLeu: 3.499 ± 0.289
1.166GlnMet: 1.166 ± 0.622
1.555GlnAsn: 1.555 ± 0.861
1.555GlnPro: 1.555 ± 0.267
1.166GlnGln: 1.166 ± 0.096
1.555GlnArg: 1.555 ± 0.861
2.333GlnSer: 2.333 ± 0.995
3.888GlnThr: 3.888 ± 1.262
0.778GlnVal: 0.778 ± 0.46
0.389GlnTrp: 0.389 ± 0.23
0.389GlnTyr: 0.389 ± 0.364
0.0GlnXaa: 0.0 ± 0.0
Arg
2.722ArgAla: 2.722 ± 0.171
0.389ArgCys: 0.389 ± 0.23
2.333ArgAsp: 2.333 ± 0.401
1.944ArgGlu: 1.944 ± 0.556
3.11ArgPhe: 3.11 ± 0.059
2.333ArgGly: 2.333 ± 0.193
1.555ArgHis: 1.555 ± 0.92
2.722ArgIle: 2.722 ± 0.423
5.443ArgLys: 5.443 ± 0.936
3.11ArgLeu: 3.11 ± 1.246
0.389ArgMet: 0.389 ± 0.23
1.555ArgAsn: 1.555 ± 0.267
1.944ArgPro: 1.944 ± 0.631
0.389ArgGln: 0.389 ± 0.364
3.888ArgArg: 3.888 ± 1.706
3.11ArgSer: 3.11 ± 0.535
3.11ArgThr: 3.11 ± 0.653
2.333ArgVal: 2.333 ± 0.401
0.0ArgTrp: 0.0 ± 0.0
2.722ArgTyr: 2.722 ± 1.358
0.0ArgXaa: 0.0 ± 0.0
Ser
3.11SerAla: 3.11 ± 1.246
0.389SerCys: 0.389 ± 0.23
3.499SerAsp: 3.499 ± 0.289
4.277SerGlu: 4.277 ± 1.343
4.277SerPhe: 4.277 ± 0.749
5.443SerGly: 5.443 ± 1.529
1.555SerHis: 1.555 ± 0.326
2.722SerIle: 2.722 ± 0.765
6.221SerLys: 6.221 ± 0.118
5.054SerLeu: 5.054 ± 1.166
2.333SerMet: 2.333 ± 0.603
2.333SerAsn: 2.333 ± 0.193
3.499SerPro: 3.499 ± 0.898
5.443SerGln: 5.443 ± 1.529
2.722SerArg: 2.722 ± 0.765
3.499SerSer: 3.499 ± 0.289
3.11SerThr: 3.11 ± 1.128
5.832SerVal: 5.832 ± 0.482
0.778SerTrp: 0.778 ± 0.134
3.499SerTyr: 3.499 ± 0.289
0.0SerXaa: 0.0 ± 0.0
Thr
3.499ThrAla: 3.499 ± 0.305
0.389ThrCys: 0.389 ± 0.23
2.722ThrAsp: 2.722 ± 0.765
1.944ThrGlu: 1.944 ± 0.631
2.333ThrPhe: 2.333 ± 0.193
3.888ThrGly: 3.888 ± 0.075
1.555ThrHis: 1.555 ± 0.326
5.832ThrIle: 5.832 ± 0.482
2.722ThrLys: 2.722 ± 1.016
5.443ThrLeu: 5.443 ± 1.439
1.166ThrMet: 1.166 ± 0.096
3.888ThrAsn: 3.888 ± 1.856
4.277ThrPro: 4.277 ± 1.626
1.555ThrGln: 1.555 ± 0.326
3.499ThrArg: 3.499 ± 0.898
5.832ThrSer: 5.832 ± 0.705
7.776ThrThr: 7.776 ± 1.336
5.832ThrVal: 5.832 ± 1.299
0.389ThrTrp: 0.389 ± 0.364
2.333ThrTyr: 2.333 ± 0.786
0.0ThrXaa: 0.0 ± 0.0
Val
5.443ValAla: 5.443 ± 0.252
0.389ValCys: 0.389 ± 0.23
5.832ValAsp: 5.832 ± 0.705
2.333ValGlu: 2.333 ± 0.193
2.333ValPhe: 2.333 ± 0.193
6.221ValGly: 6.221 ± 0.712
1.166ValHis: 1.166 ± 1.091
3.888ValIle: 3.888 ± 0.075
3.11ValLys: 3.11 ± 0.653
7.387ValLeu: 7.387 ± 0.379
1.555ValMet: 1.555 ± 0.326
4.277ValAsn: 4.277 ± 0.155
3.888ValPro: 3.888 ± 0.519
0.778ValGln: 0.778 ± 0.134
2.722ValArg: 2.722 ± 0.765
3.888ValSer: 3.888 ± 0.668
5.443ValThr: 5.443 ± 1.529
5.054ValVal: 5.054 ± 0.572
0.778ValTrp: 0.778 ± 0.46
3.11ValTyr: 3.11 ± 0.059
0.0ValXaa: 0.0 ± 0.0
Trp
0.389TrpAla: 0.389 ± 0.364
0.0TrpCys: 0.0 ± 0.0
1.166TrpAsp: 1.166 ± 0.096
0.389TrpGlu: 0.389 ± 0.23
0.389TrpPhe: 0.389 ± 0.23
0.778TrpGly: 0.778 ± 0.134
0.389TrpHis: 0.389 ± 0.364
0.0TrpIle: 0.0 ± 0.0
0.778TrpLys: 0.778 ± 0.46
1.555TrpLeu: 1.555 ± 0.326
0.389TrpMet: 0.389 ± 0.23
1.555TrpAsn: 1.555 ± 0.267
0.0TrpPro: 0.0 ± 0.0
1.166TrpGln: 1.166 ± 0.497
0.778TrpArg: 0.778 ± 0.134
1.166TrpSer: 1.166 ± 1.091
1.166TrpThr: 1.166 ± 0.69
0.389TrpVal: 0.389 ± 0.364
0.0TrpTrp: 0.0 ± 0.0
1.166TrpTyr: 1.166 ± 0.096
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.944TyrAla: 1.944 ± 0.037
0.389TyrCys: 0.389 ± 0.23
3.11TyrAsp: 3.11 ± 0.059
1.944TyrGlu: 1.944 ± 0.037
1.944TyrPhe: 1.944 ± 0.556
3.888TyrGly: 3.888 ± 0.668
1.166TyrHis: 1.166 ± 0.497
0.778TyrIle: 0.778 ± 0.46
1.944TyrLys: 1.944 ± 0.556
2.333TyrLeu: 2.333 ± 0.401
0.389TyrMet: 0.389 ± 0.23
3.11TyrAsn: 3.11 ± 1.128
0.0TyrPro: 0.0 ± 0.0
1.944TyrGln: 1.944 ± 0.631
1.944TyrArg: 1.944 ± 0.037
2.722TyrSer: 2.722 ± 0.171
1.555TyrThr: 1.555 ± 0.326
4.666TyrVal: 4.666 ± 0.208
0.0TyrTrp: 0.0 ± 0.0
1.555TyrTyr: 1.555 ± 0.267
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2573 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski