Amino acid dipepetide frequency for Moraxella bovoculi 237

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.787AlaAla: 6.787 ± 0.169
1.113AlaCys: 1.113 ± 0.051
5.952AlaAsp: 5.952 ± 0.107
4.494AlaGlu: 4.494 ± 0.101
3.468AlaPhe: 3.468 ± 0.096
6.684AlaGly: 6.684 ± 0.109
2.264AlaHis: 2.264 ± 0.065
6.543AlaIle: 6.543 ± 0.119
6.242AlaLys: 6.242 ± 0.121
10.033AlaLeu: 10.033 ± 0.165
2.843AlaMet: 2.843 ± 0.081
4.115AlaAsn: 4.115 ± 0.089
3.287AlaPro: 3.287 ± 0.089
3.976AlaGln: 3.976 ± 0.093
4.075AlaArg: 4.075 ± 0.088
5.004AlaSer: 5.004 ± 0.083
5.082AlaThr: 5.082 ± 0.094
6.376AlaVal: 6.376 ± 0.129
1.099AlaTrp: 1.099 ± 0.048
2.672AlaTyr: 2.672 ± 0.075
0.0AlaXaa: 0.0 ± 0.0
Cys
0.842CysAla: 0.842 ± 0.04
0.112CysCys: 0.112 ± 0.017
0.593CysAsp: 0.593 ± 0.031
0.506CysGlu: 0.506 ± 0.033
0.382CysPhe: 0.382 ± 0.027
0.848CysGly: 0.848 ± 0.04
0.379CysHis: 0.379 ± 0.026
0.506CysIle: 0.506 ± 0.028
0.367CysLys: 0.367 ± 0.024
0.919CysLeu: 0.919 ± 0.039
0.231CysMet: 0.231 ± 0.018
0.306CysAsn: 0.306 ± 0.022
0.453CysPro: 0.453 ± 0.032
0.596CysGln: 0.596 ± 0.036
0.375CysArg: 0.375 ± 0.025
0.455CysSer: 0.455 ± 0.029
0.496CysThr: 0.496 ± 0.027
0.683CysVal: 0.683 ± 0.033
0.065CysTrp: 0.065 ± 0.011
0.287CysTyr: 0.287 ± 0.027
0.0CysXaa: 0.0 ± 0.0
Asp
5.157AspAla: 5.157 ± 0.107
0.518AspCys: 0.518 ± 0.032
4.771AspAsp: 4.771 ± 0.122
5.264AspGlu: 5.264 ± 0.123
2.694AspPhe: 2.694 ± 0.068
4.757AspGly: 4.757 ± 0.119
1.23AspHis: 1.23 ± 0.043
4.301AspIle: 4.301 ± 0.085
4.732AspLys: 4.732 ± 0.102
5.321AspLeu: 5.321 ± 0.107
1.637AspMet: 1.637 ± 0.056
3.249AspAsn: 3.249 ± 0.089
1.807AspPro: 1.807 ± 0.062
1.486AspGln: 1.486 ± 0.047
2.383AspArg: 2.383 ± 0.075
2.966AspSer: 2.966 ± 0.08
3.321AspThr: 3.321 ± 0.087
4.669AspVal: 4.669 ± 0.095
0.824AspTrp: 0.824 ± 0.037
2.228AspTyr: 2.228 ± 0.064
0.0AspXaa: 0.0 ± 0.0
Glu
4.175GluAla: 4.175 ± 0.106
0.489GluCys: 0.489 ± 0.032
2.374GluAsp: 2.374 ± 0.074
2.517GluGlu: 2.517 ± 0.084
2.419GluPhe: 2.419 ± 0.066
2.886GluGly: 2.886 ± 0.079
1.5GluHis: 1.5 ± 0.052
3.693GluIle: 3.693 ± 0.086
2.726GluLys: 2.726 ± 0.072
6.269GluLeu: 6.269 ± 0.106
1.518GluMet: 1.518 ± 0.054
2.476GluAsn: 2.476 ± 0.072
1.996GluPro: 1.996 ± 0.055
2.799GluGln: 2.799 ± 0.074
3.385GluArg: 3.385 ± 0.083
2.983GluSer: 2.983 ± 0.073
2.634GluThr: 2.634 ± 0.074
3.472GluVal: 3.472 ± 0.084
0.676GluTrp: 0.676 ± 0.036
1.768GluTyr: 1.768 ± 0.061
0.0GluXaa: 0.0 ± 0.0
Phe
3.823PheAla: 3.823 ± 0.093
0.503PheCys: 0.503 ± 0.029
3.397PheAsp: 3.397 ± 0.084
2.361PheGlu: 2.361 ± 0.06
1.77PhePhe: 1.77 ± 0.069
3.817PheGly: 3.817 ± 0.086
0.78PheHis: 0.78 ± 0.034
2.826PheIle: 2.826 ± 0.074
1.879PheLys: 1.879 ± 0.063
3.531PheLeu: 3.531 ± 0.092
1.102PheMet: 1.102 ± 0.047
1.992PheAsn: 1.992 ± 0.055
0.995PhePro: 0.995 ± 0.05
0.708PheGln: 0.708 ± 0.033
1.253PheArg: 1.253 ± 0.039
2.468PheSer: 2.468 ± 0.068
2.018PheThr: 2.018 ± 0.054
2.937PheVal: 2.937 ± 0.07
0.516PheTrp: 0.516 ± 0.031
1.428PheTyr: 1.428 ± 0.048
0.0PheXaa: 0.0 ± 0.0
Gly
6.031GlyAla: 6.031 ± 0.105
0.78GlyCys: 0.78 ± 0.034
4.124GlyAsp: 4.124 ± 0.095
4.341GlyGlu: 4.341 ± 0.094
3.334GlyPhe: 3.334 ± 0.08
5.264GlyGly: 5.264 ± 0.134
1.423GlyHis: 1.423 ± 0.052
4.824GlyIle: 4.824 ± 0.109
4.526GlyLys: 4.526 ± 0.103
7.11GlyLeu: 7.11 ± 0.116
2.223GlyMet: 2.223 ± 0.064
2.728GlyAsn: 2.728 ± 0.093
0.846GlyPro: 0.846 ± 0.044
2.836GlyGln: 2.836 ± 0.069
3.46GlyArg: 3.46 ± 0.081
3.733GlySer: 3.733 ± 0.069
3.558GlyThr: 3.558 ± 0.085
6.607GlyVal: 6.607 ± 0.11
0.785GlyTrp: 0.785 ± 0.037
2.504GlyTyr: 2.504 ± 0.079
0.0GlyXaa: 0.0 ± 0.0
His
2.487HisAla: 2.487 ± 0.063
0.217HisCys: 0.217 ± 0.022
1.546HisAsp: 1.546 ± 0.063
1.435HisGlu: 1.435 ± 0.059
0.88HisPhe: 0.88 ± 0.034
1.824HisGly: 1.824 ± 0.062
0.995HisHis: 0.995 ± 0.048
1.649HisIle: 1.649 ± 0.061
1.14HisLys: 1.14 ± 0.045
2.454HisLeu: 2.454 ± 0.068
0.469HisMet: 0.469 ± 0.03
0.968HisAsn: 0.968 ± 0.042
1.197HisPro: 1.197 ± 0.044
1.243HisGln: 1.243 ± 0.051
1.257HisArg: 1.257 ± 0.054
1.296HisSer: 1.296 ± 0.044
1.413HisThr: 1.413 ± 0.046
1.286HisVal: 1.286 ± 0.045
0.279HisTrp: 0.279 ± 0.021
0.875HisTyr: 0.875 ± 0.042
0.0HisXaa: 0.0 ± 0.0
Ile
6.692IleAla: 6.692 ± 0.132
0.737IleCys: 0.737 ± 0.037
4.815IleAsp: 4.815 ± 0.09
3.747IleGlu: 3.747 ± 0.089
2.48IlePhe: 2.48 ± 0.072
5.158IleGly: 5.158 ± 0.102
1.608IleHis: 1.608 ± 0.053
4.684IleIle: 4.684 ± 0.087
4.151IleLys: 4.151 ± 0.078
5.7IleLeu: 5.7 ± 0.106
1.556IleMet: 1.556 ± 0.059
3.321IleAsn: 3.321 ± 0.086
2.232IlePro: 2.232 ± 0.066
2.089IleGln: 2.089 ± 0.075
2.797IleArg: 2.797 ± 0.063
4.172IleSer: 4.172 ± 0.095
4.1IleThr: 4.1 ± 0.082
4.204IleVal: 4.204 ± 0.082
0.613IleTrp: 0.613 ± 0.034
1.941IleTyr: 1.941 ± 0.071
0.0IleXaa: 0.0 ± 0.0
Lys
5.367LysAla: 5.367 ± 0.103
0.292LysCys: 0.292 ± 0.023
3.82LysAsp: 3.82 ± 0.093
2.983LysGlu: 2.983 ± 0.074
1.967LysPhe: 1.967 ± 0.062
3.448LysGly: 3.448 ± 0.097
1.35LysHis: 1.35 ± 0.045
3.65LysIle: 3.65 ± 0.081
3.283LysLys: 3.283 ± 0.1
5.34LysLeu: 5.34 ± 0.107
1.447LysMet: 1.447 ± 0.054
2.853LysAsn: 2.853 ± 0.08
2.514LysPro: 2.514 ± 0.073
2.628LysGln: 2.628 ± 0.071
2.663LysArg: 2.663 ± 0.073
3.66LysSer: 3.66 ± 0.074
3.467LysThr: 3.467 ± 0.076
3.587LysVal: 3.587 ± 0.088
0.605LysTrp: 0.605 ± 0.031
1.468LysTyr: 1.468 ± 0.053
0.0LysXaa: 0.0 ± 0.0
Leu
10.065LeuAla: 10.065 ± 0.137
0.939LeuCys: 0.939 ± 0.041
6.25LeuAsp: 6.25 ± 0.108
4.382LeuGlu: 4.382 ± 0.095
3.699LeuPhe: 3.699 ± 0.1
7.475LeuGly: 7.475 ± 0.111
2.113LeuHis: 2.113 ± 0.065
6.505LeuIle: 6.505 ± 0.138
5.231LeuLys: 5.231 ± 0.1
9.245LeuLeu: 9.245 ± 0.192
2.743LeuMet: 2.743 ± 0.083
4.649LeuAsn: 4.649 ± 0.106
5.265LeuPro: 5.265 ± 0.098
3.477LeuGln: 3.477 ± 0.099
3.811LeuArg: 3.811 ± 0.082
7.934LeuSer: 7.934 ± 0.142
6.408LeuThr: 6.408 ± 0.105
6.227LeuVal: 6.227 ± 0.131
1.126LeuTrp: 1.126 ± 0.048
2.561LeuTyr: 2.561 ± 0.064
0.0LeuXaa: 0.0 ± 0.0
Met
2.772MetAla: 2.772 ± 0.074
0.211MetCys: 0.211 ± 0.018
1.225MetAsp: 1.225 ± 0.052
0.812MetGlu: 0.812 ± 0.043
0.873MetPhe: 0.873 ± 0.044
2.016MetGly: 2.016 ± 0.069
0.545MetHis: 0.545 ± 0.028
1.651MetIle: 1.651 ± 0.058
1.303MetLys: 1.303 ± 0.052
2.66MetLeu: 2.66 ± 0.068
0.953MetMet: 0.953 ± 0.043
1.534MetAsn: 1.534 ± 0.045
1.282MetPro: 1.282 ± 0.05
1.187MetGln: 1.187 ± 0.041
1.257MetArg: 1.257 ± 0.044
2.008MetSer: 2.008 ± 0.056
2.111MetThr: 2.111 ± 0.062
1.783MetVal: 1.783 ± 0.064
0.221MetTrp: 0.221 ± 0.019
0.598MetTyr: 0.598 ± 0.037
0.0MetXaa: 0.0 ± 0.0
Asn
4.397AsnAla: 4.397 ± 0.079
0.365AsnCys: 0.365 ± 0.023
2.921AsnAsp: 2.921 ± 0.067
2.342AsnGlu: 2.342 ± 0.061
1.717AsnPhe: 1.717 ± 0.056
2.916AsnGly: 2.916 ± 0.099
1.347AsnHis: 1.347 ± 0.058
3.186AsnIle: 3.186 ± 0.078
2.482AsnLys: 2.482 ± 0.065
4.438AsnLeu: 4.438 ± 0.083
1.012AsnMet: 1.012 ± 0.045
2.225AsnAsn: 2.225 ± 0.085
2.556AsnPro: 2.556 ± 0.072
2.189AsnGln: 2.189 ± 0.079
1.984AsnArg: 1.984 ± 0.064
2.293AsnSer: 2.293 ± 0.059
2.667AsnThr: 2.667 ± 0.081
2.614AsnVal: 2.614 ± 0.072
0.544AsnTrp: 0.544 ± 0.039
1.344AsnTyr: 1.344 ± 0.043
0.0AsnXaa: 0.0 ± 0.0
Pro
3.453ProAla: 3.453 ± 0.079
0.311ProCys: 0.311 ± 0.024
2.442ProAsp: 2.442 ± 0.066
2.089ProGlu: 2.089 ± 0.066
1.637ProPhe: 1.637 ± 0.052
1.004ProGly: 1.004 ± 0.046
0.858ProHis: 0.858 ± 0.039
2.893ProIle: 2.893 ± 0.067
2.814ProLys: 2.814 ± 0.065
3.594ProLeu: 3.594 ± 0.085
1.13ProMet: 1.13 ± 0.043
2.356ProAsn: 2.356 ± 0.063
1.242ProPro: 1.242 ± 0.045
1.306ProGln: 1.306 ± 0.049
1.376ProArg: 1.376 ± 0.054
2.578ProSer: 2.578 ± 0.063
2.689ProThr: 2.689 ± 0.071
2.877ProVal: 2.877 ± 0.074
0.375ProTrp: 0.375 ± 0.026
1.269ProTyr: 1.269 ± 0.046
0.0ProXaa: 0.0 ± 0.0
Gln
4.538GlnAla: 4.538 ± 0.092
0.246GlnCys: 0.246 ± 0.02
2.364GlnAsp: 2.364 ± 0.071
1.979GlnGlu: 1.979 ± 0.066
1.515GlnPhe: 1.515 ± 0.05
2.971GlnGly: 2.971 ± 0.081
0.82GlnHis: 0.82 ± 0.038
2.848GlnIle: 2.848 ± 0.082
2.639GlnLys: 2.639 ± 0.069
3.555GlnLeu: 3.555 ± 0.071
1.22GlnMet: 1.22 ± 0.041
2.234GlnAsn: 2.234 ± 0.081
1.316GlnPro: 1.316 ± 0.046
1.374GlnGln: 1.374 ± 0.065
1.576GlnArg: 1.576 ± 0.053
2.675GlnSer: 2.675 ± 0.089
2.534GlnThr: 2.534 ± 0.072
2.82GlnVal: 2.82 ± 0.075
0.321GlnTrp: 0.321 ± 0.025
1.096GlnTyr: 1.096 ± 0.042
0.0GlnXaa: 0.0 ± 0.0
Arg
4.019ArgAla: 4.019 ± 0.082
0.382ArgCys: 0.382 ± 0.028
2.332ArgAsp: 2.332 ± 0.061
2.398ArgGlu: 2.398 ± 0.064
2.128ArgPhe: 2.128 ± 0.056
2.735ArgGly: 2.735 ± 0.068
1.386ArgHis: 1.386 ± 0.045
3.047ArgIle: 3.047 ± 0.073
1.873ArgLys: 1.873 ± 0.062
5.276ArgLeu: 5.276 ± 0.108
1.187ArgMet: 1.187 ± 0.045
1.405ArgAsn: 1.405 ± 0.052
1.792ArgPro: 1.792 ± 0.05
2.291ArgGln: 2.291 ± 0.058
2.223ArgArg: 2.223 ± 0.071
2.171ArgSer: 2.171 ± 0.057
2.543ArgThr: 2.543 ± 0.059
2.859ArgVal: 2.859 ± 0.085
0.479ArgTrp: 0.479 ± 0.029
1.831ArgTyr: 1.831 ± 0.058
0.0ArgXaa: 0.0 ± 0.0
Ser
5.466SerAla: 5.466 ± 0.105
0.493SerCys: 0.493 ± 0.034
3.993SerAsp: 3.993 ± 0.072
3.251SerGlu: 3.251 ± 0.063
2.563SerPhe: 2.563 ± 0.069
4.391SerGly: 4.391 ± 0.089
1.722SerHis: 1.722 ± 0.061
3.586SerIle: 3.586 ± 0.079
2.748SerLys: 2.748 ± 0.071
6.393SerLeu: 6.393 ± 0.108
1.573SerMet: 1.573 ± 0.057
2.23SerAsn: 2.23 ± 0.076
2.288SerPro: 2.288 ± 0.071
2.568SerGln: 2.568 ± 0.067
2.696SerArg: 2.696 ± 0.069
3.545SerSer: 3.545 ± 0.08
3.168SerThr: 3.168 ± 0.069
4.323SerVal: 4.323 ± 0.096
0.603SerTrp: 0.603 ± 0.034
1.816SerTyr: 1.816 ± 0.061
0.0SerXaa: 0.0 ± 0.0
Thr
5.732ThrAla: 5.732 ± 0.105
0.479ThrCys: 0.479 ± 0.029
3.648ThrAsp: 3.648 ± 0.092
2.512ThrGlu: 2.512 ± 0.072
1.812ThrPhe: 1.812 ± 0.05
4.459ThrGly: 4.459 ± 0.099
1.76ThrHis: 1.76 ± 0.069
3.439ThrIle: 3.439 ± 0.074
3.062ThrLys: 3.062 ± 0.074
6.378ThrLeu: 6.378 ± 0.117
1.14ThrMet: 1.14 ± 0.045
2.33ThrAsn: 2.33 ± 0.079
3.273ThrPro: 3.273 ± 0.075
2.561ThrGln: 2.561 ± 0.068
2.293ThrArg: 2.293 ± 0.064
2.906ThrSer: 2.906 ± 0.069
3.448ThrThr: 3.448 ± 0.09
3.817ThrVal: 3.817 ± 0.087
0.574ThrTrp: 0.574 ± 0.03
1.512ThrTyr: 1.512 ± 0.054
0.0ThrXaa: 0.0 ± 0.0
Val
6.806ValAla: 6.806 ± 0.129
0.769ValCys: 0.769 ± 0.038
4.18ValAsp: 4.18 ± 0.093
3.251ValGlu: 3.251 ± 0.086
2.808ValPhe: 2.808 ± 0.075
5.338ValGly: 5.338 ± 0.122
1.456ValHis: 1.456 ± 0.054
4.803ValIle: 4.803 ± 0.095
3.524ValLys: 3.524 ± 0.1
6.998ValLeu: 6.998 ± 0.11
2.152ValMet: 2.152 ± 0.059
3.056ValAsn: 3.056 ± 0.072
2.487ValPro: 2.487 ± 0.077
2.412ValGln: 2.412 ± 0.062
3.244ValArg: 3.244 ± 0.077
4.55ValSer: 4.55 ± 0.096
3.353ValThr: 3.353 ± 0.091
5.374ValVal: 5.374 ± 0.118
0.786ValTrp: 0.786 ± 0.04
1.856ValTyr: 1.856 ± 0.057
0.0ValXaa: 0.0 ± 0.0
Trp
0.927TrpAla: 0.927 ± 0.044
0.132TrpCys: 0.132 ± 0.017
0.484TrpAsp: 0.484 ± 0.029
0.442TrpGlu: 0.442 ± 0.031
0.561TrpPhe: 0.561 ± 0.029
0.763TrpGly: 0.763 ± 0.04
0.353TrpHis: 0.353 ± 0.025
0.625TrpIle: 0.625 ± 0.031
0.296TrpLys: 0.296 ± 0.024
1.631TrpLeu: 1.631 ± 0.055
0.27TrpMet: 0.27 ± 0.02
0.26TrpAsn: 0.26 ± 0.021
0.129TrpPro: 0.129 ± 0.016
1.107TrpGln: 1.107 ± 0.048
0.649TrpArg: 0.649 ± 0.034
0.527TrpSer: 0.527 ± 0.028
0.508TrpThr: 0.508 ± 0.031
0.82TrpVal: 0.82 ± 0.044
0.149TrpTrp: 0.149 ± 0.019
0.375TrpTyr: 0.375 ± 0.031
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.57TyrAla: 2.57 ± 0.06
0.313TyrCys: 0.313 ± 0.025
2.084TyrAsp: 2.084 ± 0.078
1.649TyrGlu: 1.649 ± 0.05
1.398TyrPhe: 1.398 ± 0.052
2.286TyrGly: 2.286 ± 0.066
1.021TyrHis: 1.021 ± 0.039
1.539TyrIle: 1.539 ± 0.051
1.372TyrLys: 1.372 ± 0.049
3.263TyrLeu: 3.263 ± 0.08
0.593TyrMet: 0.593 ± 0.028
1.253TyrAsn: 1.253 ± 0.052
1.335TyrPro: 1.335 ± 0.047
1.806TyrGln: 1.806 ± 0.053
1.598TyrArg: 1.598 ± 0.055
1.491TyrSer: 1.491 ± 0.05
1.619TyrThr: 1.619 ± 0.055
1.87TyrVal: 1.87 ± 0.065
0.369TyrTrp: 0.369 ± 0.027
1.05TyrTyr: 1.05 ± 0.043
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 1900 proteins (588757 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski