Amino acid dipepetide frequency for Ilumatobacter coccineus (strain NBRC 103263 / KCTC 29153 / YM16-304)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	17.311AlaAla: 17.311 ± 0.188	1.019AlaCys: 1.019 ± 0.034	9.72AlaAsp: 9.72 ± 0.091	7.536AlaGlu: 7.536 ± 0.091	3.569AlaPhe: 3.569 ± 0.055	10.679AlaGly: 10.679 ± 0.113	2.228AlaHis: 2.228 ± 0.048	5.905AlaIle: 5.905 ± 0.057	2.421AlaLys: 2.421 ± 0.057	10.812AlaLeu: 10.812 ± 0.123	2.871AlaMet: 2.871 ± 0.06	2.74AlaAsn: 2.74 ± 0.05	6.167AlaPro: 6.167 ± 0.085	2.891AlaGln: 2.891 ± 0.047	7.213AlaArg: 7.213 ± 0.102	7.272AlaSer: 7.272 ± 0.07	8.15AlaThr: 8.15 ± 0.086	10.077AlaVal: 10.077 ± 0.098	1.539AlaTrp: 1.539 ± 0.035	1.93AlaTyr: 1.93 ± 0.036	0.0AlaXaa: 0.0 ± 0.0
Cys	0.936CysAla: 0.936 ± 0.036	0.103CysCys: 0.103 ± 0.008	0.655CysAsp: 0.655 ± 0.023	0.473CysGlu: 0.473 ± 0.021	0.254CysPhe: 0.254 ± 0.013	0.937CysGly: 0.937 ± 0.033	0.204CysHis: 0.204 ± 0.012	0.334CysIle: 0.334 ± 0.014	0.119CysLys: 0.119 ± 0.009	0.643CysLeu: 0.643 ± 0.025	0.122CysMet: 0.122 ± 0.008	0.196CysAsn: 0.196 ± 0.012	0.46CysPro: 0.46 ± 0.019	0.186CysGln: 0.186 ± 0.011	0.557CysArg: 0.557 ± 0.02	0.57CysSer: 0.57 ± 0.03	0.549CysThr: 0.549 ± 0.026	0.652CysVal: 0.652 ± 0.023	0.185CysTrp: 0.185 ± 0.026	0.151CysTyr: 0.151 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	9.53AspAla: 9.53 ± 0.097	0.453AspCys: 0.453 ± 0.02	7.624AspAsp: 7.624 ± 0.1	5.776AspGlu: 5.776 ± 0.074	2.05AspPhe: 2.05 ± 0.044	8.142AspGly: 8.142 ± 0.114	1.777AspHis: 1.777 ± 0.042	2.968AspIle: 2.968 ± 0.049	0.958AspLys: 0.958 ± 0.024	7.111AspLeu: 7.111 ± 0.075	1.209AspMet: 1.209 ± 0.028	1.346AspAsn: 1.346 ± 0.041	4.869AspPro: 4.869 ± 0.072	1.949AspGln: 1.949 ± 0.036	5.257AspArg: 5.257 ± 0.078	3.195AspSer: 3.195 ± 0.053	4.125AspThr: 4.125 ± 0.069	6.933AspVal: 6.933 ± 0.076	1.059AspTrp: 1.059 ± 0.028	1.226AspTyr: 1.226 ± 0.032	0.0AspXaa: 0.0 ± 0.0
Glu	6.812GluAla: 6.812 ± 0.088	0.426GluCys: 0.426 ± 0.018	1.88GluAsp: 1.88 ± 0.043	2.54GluGlu: 2.54 ± 0.052	2.161GluPhe: 2.161 ± 0.041	3.428GluGly: 3.428 ± 0.054	1.774GluHis: 1.774 ± 0.046	3.305GluIle: 3.305 ± 0.053	1.015GluLys: 1.015 ± 0.031	6.956GluLeu: 6.956 ± 0.083	1.347GluMet: 1.347 ± 0.032	1.196GluAsn: 1.196 ± 0.031	3.75GluPro: 3.75 ± 0.07	2.386GluGln: 2.386 ± 0.045	5.517GluArg: 5.517 ± 0.074	3.383GluSer: 3.383 ± 0.053	3.117GluThr: 3.117 ± 0.046	4.834GluVal: 4.834 ± 0.059	0.909GluTrp: 0.909 ± 0.028	1.104GluTyr: 1.104 ± 0.035	0.0GluXaa: 0.0 ± 0.0
Phe	3.91PheAla: 3.91 ± 0.054	0.341PheCys: 0.341 ± 0.014	3.239PheAsp: 3.239 ± 0.046	2.098PheGlu: 2.098 ± 0.037	1.076PhePhe: 1.076 ± 0.034	3.515PheGly: 3.515 ± 0.057	0.662PheHis: 0.662 ± 0.023	1.168PheIle: 1.168 ± 0.03	0.474PheLys: 0.474 ± 0.021	2.339PheLeu: 2.339 ± 0.049	0.505PheMet: 0.505 ± 0.021	0.75PheAsn: 0.75 ± 0.025	1.476PhePro: 1.476 ± 0.035	0.716PheGln: 0.716 ± 0.022	1.726PheArg: 1.726 ± 0.035	1.786PheSer: 1.786 ± 0.034	2.091PheThr: 2.091 ± 0.044	3.154PheVal: 3.154 ± 0.054	0.413PheTrp: 0.413 ± 0.017	0.596PheTyr: 0.596 ± 0.023	0.0PheXaa: 0.0 ± 0.0
Gly	9.712GlyAla: 9.712 ± 0.101	0.784GlyCys: 0.784 ± 0.028	6.751GlyAsp: 6.751 ± 0.102	5.077GlyGlu: 5.077 ± 0.064	3.235GlyPhe: 3.235 ± 0.049	7.686GlyGly: 7.686 ± 0.104	1.865GlyHis: 1.865 ± 0.04	4.094GlyIle: 4.094 ± 0.06	1.896GlyLys: 1.896 ± 0.039	7.963GlyLeu: 7.963 ± 0.088	1.823GlyMet: 1.823 ± 0.035	2.196GlyAsn: 2.196 ± 0.062	4.223GlyPro: 4.223 ± 0.093	2.331GlyGln: 2.331 ± 0.049	6.069GlyArg: 6.069 ± 0.069	5.858GlySer: 5.858 ± 0.076	5.761GlyThr: 5.761 ± 0.115	7.738GlyVal: 7.738 ± 0.087	1.488GlyTrp: 1.488 ± 0.038	2.034GlyTyr: 2.034 ± 0.047	0.0GlyXaa: 0.0 ± 0.0
His	2.331HisAla: 2.331 ± 0.041	0.2HisCys: 0.2 ± 0.012	1.852HisAsp: 1.852 ± 0.041	1.211HisGlu: 1.211 ± 0.028	0.629HisPhe: 0.629 ± 0.021	2.031HisGly: 2.031 ± 0.044	0.724HisHis: 0.724 ± 0.027	0.726HisIle: 0.726 ± 0.021	0.279HisLys: 0.279 ± 0.013	2.234HisLeu: 2.234 ± 0.044	0.355HisMet: 0.355 ± 0.016	0.383HisAsn: 0.383 ± 0.015	1.48HisPro: 1.48 ± 0.032	0.586HisGln: 0.586 ± 0.02	1.803HisArg: 1.803 ± 0.042	0.913HisSer: 0.913 ± 0.028	1.103HisThr: 1.103 ± 0.035	1.815HisVal: 1.815 ± 0.04	0.324HisTrp: 0.324 ± 0.014	0.385HisTyr: 0.385 ± 0.017	0.0HisXaa: 0.0 ± 0.0
Ile	6.484IleAla: 6.484 ± 0.072	0.379IleCys: 0.379 ± 0.016	5.056IleAsp: 5.056 ± 0.067	3.675IleGlu: 3.675 ± 0.053	1.026IlePhe: 1.026 ± 0.029	4.95IleGly: 4.95 ± 0.063	0.816IleHis: 0.816 ± 0.024	1.771IleIle: 1.771 ± 0.042	0.731IleLys: 0.731 ± 0.022	2.659IleLeu: 2.659 ± 0.049	0.631IleMet: 0.631 ± 0.021	1.108IleAsn: 1.108 ± 0.029	2.249IlePro: 2.249 ± 0.04	0.909IleGln: 0.909 ± 0.026	2.634IleArg: 2.634 ± 0.04	2.525IleSer: 2.525 ± 0.04	3.208IleThr: 3.208 ± 0.062	4.641IleVal: 4.641 ± 0.063	0.532IleTrp: 0.532 ± 0.018	0.701IleTyr: 0.701 ± 0.022	0.0IleXaa: 0.0 ± 0.0
Lys	2.059LysAla: 2.059 ± 0.048	0.141LysCys: 0.141 ± 0.014	0.769LysAsp: 0.769 ± 0.028	0.846LysGlu: 0.846 ± 0.03	0.562LysPhe: 0.562 ± 0.021	1.261LysGly: 1.261 ± 0.034	0.423LysHis: 0.423 ± 0.017	0.977LysIle: 0.977 ± 0.026	0.743LysLys: 0.743 ± 0.045	1.807LysLeu: 1.807 ± 0.035	0.441LysMet: 0.441 ± 0.02	0.491LysAsn: 0.491 ± 0.022	1.037LysPro: 1.037 ± 0.032	0.647LysGln: 0.647 ± 0.024	1.565LysArg: 1.565 ± 0.036	1.106LysSer: 1.106 ± 0.031	1.11LysThr: 1.11 ± 0.034	1.665LysVal: 1.665 ± 0.038	0.262LysTrp: 0.262 ± 0.012	0.389LysTyr: 0.389 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	12.263LeuAla: 12.263 ± 0.123	0.714LeuCys: 0.714 ± 0.023	8.259LeuAsp: 8.259 ± 0.083	4.656LeuGlu: 4.656 ± 0.062	2.692LeuPhe: 2.692 ± 0.04	8.427LeuGly: 8.427 ± 0.09	1.87LeuHis: 1.87 ± 0.043	3.834LeuIle: 3.834 ± 0.066	1.416LeuLys: 1.416 ± 0.035	8.145LeuLeu: 8.145 ± 0.099	1.606LeuMet: 1.606 ± 0.034	1.872LeuAsn: 1.872 ± 0.037	4.847LeuPro: 4.847 ± 0.059	2.057LeuGln: 2.057 ± 0.037	6.118LeuArg: 6.118 ± 0.093	5.182LeuSer: 5.182 ± 0.067	5.553LeuThr: 5.553 ± 0.071	8.379LeuVal: 8.379 ± 0.088	0.976LeuTrp: 0.976 ± 0.029	1.462LeuTyr: 1.462 ± 0.035	0.0LeuXaa: 0.0 ± 0.0
Met	2.419MetAla: 2.419 ± 0.043	0.198MetCys: 0.198 ± 0.013	0.811MetAsp: 0.811 ± 0.022	0.899MetGlu: 0.899 ± 0.03	0.671MetPhe: 0.671 ± 0.022	1.405MetGly: 1.405 ± 0.031	0.417MetHis: 0.417 ± 0.017	1.102MetIle: 1.102 ± 0.026	0.503MetLys: 0.503 ± 0.015	1.999MetLeu: 1.999 ± 0.042	0.459MetMet: 0.459 ± 0.022	0.645MetAsn: 0.645 ± 0.021	1.133MetPro: 1.133 ± 0.027	0.595MetGln: 0.595 ± 0.021	1.368MetArg: 1.368 ± 0.028	1.724MetSer: 1.724 ± 0.037	1.756MetThr: 1.756 ± 0.035	1.582MetVal: 1.582 ± 0.039	0.276MetTrp: 0.276 ± 0.014	0.385MetTyr: 0.385 ± 0.018	0.0MetXaa: 0.0 ± 0.0
Asn	2.622AsnAla: 2.622 ± 0.052	0.213AsnCys: 0.213 ± 0.011	1.789AsnAsp: 1.789 ± 0.036	1.307AsnGlu: 1.307 ± 0.027	0.681AsnPhe: 0.681 ± 0.024	2.507AsnGly: 2.507 ± 0.061	0.501AsnHis: 0.501 ± 0.018	1.015AsnIle: 1.015 ± 0.031	0.425AsnLys: 0.425 ± 0.021	1.913AsnLeu: 1.913 ± 0.039	0.424AsnMet: 0.424 ± 0.018	0.627AsnAsn: 0.627 ± 0.033	1.555AsnPro: 1.555 ± 0.036	0.631AsnGln: 0.631 ± 0.022	1.442AsnArg: 1.442 ± 0.031	1.231AsnSer: 1.231 ± 0.036	1.425AsnThr: 1.425 ± 0.042	2.059AsnVal: 2.059 ± 0.04	0.342AsnTrp: 0.342 ± 0.015	0.514AsnTyr: 0.514 ± 0.021	0.0AsnXaa: 0.0 ± 0.0
Pro	6.681ProAla: 6.681 ± 0.09	0.428ProCys: 0.428 ± 0.042	5.085ProAsp: 5.085 ± 0.063	3.502ProGlu: 3.502 ± 0.062	1.718ProPhe: 1.718 ± 0.037	4.955ProGly: 4.955 ± 0.074	1.103ProHis: 1.103 ± 0.034	2.611ProIle: 2.611 ± 0.043	1.086ProLys: 1.086 ± 0.036	4.275ProLeu: 4.275 ± 0.056	1.104ProMet: 1.104 ± 0.027	1.385ProAsn: 1.385 ± 0.032	2.969ProPro: 2.969 ± 0.062	1.167ProGln: 1.167 ± 0.028	2.571ProArg: 2.571 ± 0.048	3.595ProSer: 3.595 ± 0.051	4.2ProThr: 4.2 ± 0.071	4.485ProVal: 4.485 ± 0.064	0.761ProTrp: 0.761 ± 0.025	0.965ProTyr: 0.965 ± 0.026	0.0ProXaa: 0.0 ± 0.0
Gln	2.907GlnAla: 2.907 ± 0.052	0.184GlnCys: 0.184 ± 0.011	0.976GlnAsp: 0.976 ± 0.032	1.057GlnGlu: 1.057 ± 0.029	0.949GlnPhe: 0.949 ± 0.026	1.669GlnGly: 1.669 ± 0.033	0.704GlnHis: 0.704 ± 0.024	1.531GlnIle: 1.531 ± 0.032	0.485GlnLys: 0.485 ± 0.019	2.935GlnLeu: 2.935 ± 0.05	0.606GlnMet: 0.606 ± 0.017	0.598GlnAsn: 0.598 ± 0.021	1.546GlnPro: 1.546 ± 0.038	1.08GlnGln: 1.08 ± 0.03	2.525GlnArg: 2.525 ± 0.048	1.336GlnSer: 1.336 ± 0.033	1.504GlnThr: 1.504 ± 0.035	2.169GlnVal: 2.169 ± 0.042	0.395GlnTrp: 0.395 ± 0.016	0.501GlnTyr: 0.501 ± 0.018	0.0GlnXaa: 0.0 ± 0.0
Arg	7.106ArgAla: 7.106 ± 0.086	0.639ArgCys: 0.639 ± 0.025	3.966ArgAsp: 3.966 ± 0.059	3.299ArgGlu: 3.299 ± 0.062	2.667ArgPhe: 2.667 ± 0.048	4.479ArgGly: 4.479 ± 0.06	1.685ArgHis: 1.685 ± 0.035	3.131ArgIle: 3.131 ± 0.048	1.248ArgLys: 1.248 ± 0.033	7.207ArgLeu: 7.207 ± 0.087	1.553ArgMet: 1.553 ± 0.032	1.683ArgAsn: 1.683 ± 0.036	3.742ArgPro: 3.742 ± 0.057	1.937ArgGln: 1.937 ± 0.042	6.17ArgArg: 6.17 ± 0.111	4.692ArgSer: 4.692 ± 0.069	3.82ArgThr: 3.82 ± 0.053	5.247ArgVal: 5.247 ± 0.07	1.289ArgTrp: 1.289 ± 0.033	1.439ArgTyr: 1.439 ± 0.036	0.0ArgXaa: 0.0 ± 0.0
Ser	6.675SerAla: 6.675 ± 0.077	0.494SerCys: 0.494 ± 0.023	4.345SerAsp: 4.345 ± 0.061	2.952SerGlu: 2.952 ± 0.049	2.077SerPhe: 2.077 ± 0.043	6.088SerGly: 6.088 ± 0.082	1.096SerHis: 1.096 ± 0.029	3.197SerIle: 3.197 ± 0.046	1.189SerLys: 1.189 ± 0.028	5.217SerLeu: 5.217 ± 0.056	1.575SerMet: 1.575 ± 0.032	1.529SerAsn: 1.529 ± 0.038	3.177SerPro: 3.177 ± 0.05	1.34SerGln: 1.34 ± 0.031	3.34SerArg: 3.34 ± 0.051	4.202SerSer: 4.202 ± 0.073	4.468SerThr: 4.468 ± 0.073	4.861SerVal: 4.861 ± 0.072	0.843SerTrp: 0.843 ± 0.025	1.16SerTyr: 1.16 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	7.585ThrAla: 7.585 ± 0.113	0.525ThrCys: 0.525 ± 0.028	4.86ThrAsp: 4.86 ± 0.08	3.396ThrGlu: 3.396 ± 0.051	2.13ThrPhe: 2.13 ± 0.043	6.004ThrGly: 6.004 ± 0.088	1.189ThrHis: 1.189 ± 0.033	3.516ThrIle: 3.516 ± 0.073	1.152ThrLys: 1.152 ± 0.031	5.53ThrLeu: 5.53 ± 0.072	1.373ThrMet: 1.373 ± 0.033	1.585ThrAsn: 1.585 ± 0.045	3.971ThrPro: 3.971 ± 0.068	1.389ThrGln: 1.389 ± 0.032	3.413ThrArg: 3.413 ± 0.048	4.138ThrSer: 4.138 ± 0.07	5.663ThrThr: 5.663 ± 0.151	6.001ThrVal: 6.001 ± 0.117	0.913ThrTrp: 0.913 ± 0.027	1.261ThrTyr: 1.261 ± 0.033	0.0ThrXaa: 0.0 ± 0.0
Val	11.397ValAla: 11.397 ± 0.103	0.712ValCys: 0.712 ± 0.025	7.628ValAsp: 7.628 ± 0.095	5.627ValGlu: 5.627 ± 0.06	2.673ValPhe: 2.673 ± 0.047	7.641ValGly: 7.641 ± 0.079	1.61ValHis: 1.61 ± 0.035	4.11ValIle: 4.11 ± 0.054	1.46ValLys: 1.46 ± 0.031	7.384ValLeu: 7.384 ± 0.095	1.687ValMet: 1.687 ± 0.033	1.999ValAsn: 1.999 ± 0.036	4.432ValPro: 4.432 ± 0.058	1.885ValGln: 1.885 ± 0.033	5.24ValArg: 5.24 ± 0.072	5.098ValSer: 5.098 ± 0.063	5.944ValThr: 5.944 ± 0.114	9.21ValVal: 9.21 ± 0.094	1.092ValTrp: 1.092 ± 0.027	1.381ValTyr: 1.381 ± 0.032	0.0ValXaa: 0.0 ± 0.0
Trp	1.417TrpAla: 1.417 ± 0.033	0.161TrpCys: 0.161 ± 0.012	0.812TrpAsp: 0.812 ± 0.027	0.686TrpGlu: 0.686 ± 0.02	0.599TrpPhe: 0.599 ± 0.021	1.039TrpGly: 1.039 ± 0.035	0.346TrpHis: 0.346 ± 0.016	0.751TrpIle: 0.751 ± 0.024	0.367TrpLys: 0.367 ± 0.017	1.448TrpLeu: 1.448 ± 0.035	0.379TrpMet: 0.379 ± 0.016	0.464TrpAsn: 0.464 ± 0.017	0.659TrpPro: 0.659 ± 0.023	0.422TrpGln: 0.422 ± 0.018	1.02TrpArg: 1.02 ± 0.029	1.011TrpSer: 1.011 ± 0.026	0.919TrpThr: 0.919 ± 0.028	1.064TrpVal: 1.064 ± 0.024	0.329TrpTrp: 0.329 ± 0.016	0.306TrpTyr: 0.306 ± 0.015	0.0TrpXaa: 0.0 ± 0.0
Tyr	1.893TyrAla: 1.893 ± 0.039	0.173TyrCys: 0.173 ± 0.01	1.48TyrAsp: 1.48 ± 0.033	1.224TyrGlu: 1.224 ± 0.03	0.616TyrPhe: 0.616 ± 0.021	1.742TyrGly: 1.742 ± 0.039	0.371TyrHis: 0.371 ± 0.017	0.641TyrIle: 0.641 ± 0.021	0.334TyrLys: 0.334 ± 0.018	1.748TyrLeu: 1.748 ± 0.035	0.278TyrMet: 0.278 ± 0.016	0.432TyrAsn: 0.432 ± 0.02	0.906TyrPro: 0.906 ± 0.026	0.553TyrGln: 0.553 ± 0.023	1.45TyrArg: 1.45 ± 0.034	1.005TyrSer: 1.005 ± 0.026	1.129TyrThr: 1.129 ± 0.038	1.646TyrVal: 1.646 ± 0.035	0.269TyrTrp: 0.269 ± 0.014	0.383TyrTyr: 0.383 ± 0.019	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4290 proteins (1492228 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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