Amino acid dipepetide frequency for Agromyces albus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
21.178AlaAla: 21.178 ± 0.198
0.597AlaCys: 0.597 ± 0.019
8.134AlaAsp: 8.134 ± 0.088
8.701AlaGlu: 8.701 ± 0.108
4.163AlaPhe: 4.163 ± 0.065
12.483AlaGly: 12.483 ± 0.116
2.333AlaHis: 2.333 ± 0.045
6.331AlaIle: 6.331 ± 0.089
2.558AlaLys: 2.558 ± 0.048
13.516AlaLeu: 13.516 ± 0.131
2.708AlaMet: 2.708 ± 0.051
2.406AlaAsn: 2.406 ± 0.044
6.425AlaPro: 6.425 ± 0.088
3.216AlaGln: 3.216 ± 0.057
9.301AlaArg: 9.301 ± 0.098
8.194AlaSer: 8.194 ± 0.081
7.573AlaThr: 7.573 ± 0.078
11.461AlaVal: 11.461 ± 0.112
1.952AlaTrp: 1.952 ± 0.045
2.399AlaTyr: 2.399 ± 0.047
0.0AlaXaa: 0.0 ± 0.0
Cys
0.549CysAla: 0.549 ± 0.02
0.043CysCys: 0.043 ± 0.006
0.31CysAsp: 0.31 ± 0.016
0.275CysGlu: 0.275 ± 0.014
0.15CysPhe: 0.15 ± 0.011
0.531CysGly: 0.531 ± 0.021
0.122CysHis: 0.122 ± 0.011
0.203CysIle: 0.203 ± 0.013
0.052CysLys: 0.052 ± 0.006
0.407CysLeu: 0.407 ± 0.02
0.075CysMet: 0.075 ± 0.008
0.102CysAsn: 0.102 ± 0.009
0.258CysPro: 0.258 ± 0.016
0.088CysGln: 0.088 ± 0.008
0.33CysArg: 0.33 ± 0.018
0.343CysSer: 0.343 ± 0.02
0.329CysThr: 0.329 ± 0.02
0.409CysVal: 0.409 ± 0.018
0.068CysTrp: 0.068 ± 0.008
0.096CysTyr: 0.096 ± 0.009
0.0CysXaa: 0.0 ± 0.0
Asp
9.139AspAla: 9.139 ± 0.097
0.227AspCys: 0.227 ± 0.015
4.408AspAsp: 4.408 ± 0.069
4.765AspGlu: 4.765 ± 0.066
1.851AspPhe: 1.851 ± 0.044
6.122AspGly: 6.122 ± 0.086
1.198AspHis: 1.198 ± 0.03
2.115AspIle: 2.115 ± 0.045
0.822AspLys: 0.822 ± 0.03
5.998AspLeu: 5.998 ± 0.071
0.701AspMet: 0.701 ± 0.024
0.909AspAsn: 0.909 ± 0.031
4.192AspPro: 4.192 ± 0.066
1.361AspGln: 1.361 ± 0.031
4.646AspArg: 4.646 ± 0.072
2.591AspSer: 2.591 ± 0.042
2.738AspThr: 2.738 ± 0.048
5.465AspVal: 5.465 ± 0.065
1.02AspTrp: 1.02 ± 0.029
1.285AspTyr: 1.285 ± 0.033
0.0AspXaa: 0.0 ± 0.0
Glu
7.753GluAla: 7.753 ± 0.106
0.235GluCys: 0.235 ± 0.014
2.242GluAsp: 2.242 ± 0.045
3.159GluGlu: 3.159 ± 0.059
2.057GluPhe: 2.057 ± 0.04
4.277GluGly: 4.277 ± 0.059
1.748GluHis: 1.748 ± 0.037
2.768GluIle: 2.768 ± 0.052
1.113GluLys: 1.113 ± 0.037
7.837GluLeu: 7.837 ± 0.085
0.92GluMet: 0.92 ± 0.029
1.204GluAsn: 1.204 ± 0.035
3.455GluPro: 3.455 ± 0.052
2.311GluGln: 2.311 ± 0.045
5.839GluArg: 5.839 ± 0.082
3.318GluSer: 3.318 ± 0.055
3.142GluThr: 3.142 ± 0.056
4.866GluVal: 4.866 ± 0.07
1.077GluTrp: 1.077 ± 0.026
1.271GluTyr: 1.271 ± 0.034
0.0GluXaa: 0.0 ± 0.0
Phe
4.471PheAla: 4.471 ± 0.066
0.154PheCys: 0.154 ± 0.011
2.553PheAsp: 2.553 ± 0.048
2.107PheGlu: 2.107 ± 0.047
1.065PhePhe: 1.065 ± 0.027
3.651PheGly: 3.651 ± 0.052
0.584PheHis: 0.584 ± 0.024
1.369PheIle: 1.369 ± 0.035
0.428PheLys: 0.428 ± 0.021
2.923PheLeu: 2.923 ± 0.055
0.497PheMet: 0.497 ± 0.022
0.721PheAsn: 0.721 ± 0.026
1.495PhePro: 1.495 ± 0.033
0.78PheGln: 0.78 ± 0.026
1.928PheArg: 1.928 ± 0.041
1.803PheSer: 1.803 ± 0.042
2.256PheThr: 2.256 ± 0.043
2.886PheVal: 2.886 ± 0.045
0.563PheTrp: 0.563 ± 0.025
0.654PheTyr: 0.654 ± 0.025
0.0PheXaa: 0.0 ± 0.0
Gly
10.968GlyAla: 10.968 ± 0.101
0.607GlyCys: 0.607 ± 0.023
5.295GlyAsp: 5.295 ± 0.076
5.357GlyGlu: 5.357 ± 0.068
3.492GlyPhe: 3.492 ± 0.053
7.77GlyGly: 7.77 ± 0.098
1.881GlyHis: 1.881 ± 0.049
4.87GlyIle: 4.87 ± 0.063
1.821GlyLys: 1.821 ± 0.043
8.845GlyLeu: 8.845 ± 0.095
1.902GlyMet: 1.902 ± 0.041
1.81GlyAsn: 1.81 ± 0.045
3.898GlyPro: 3.898 ± 0.052
2.23GlyGln: 2.23 ± 0.041
6.431GlyArg: 6.431 ± 0.067
5.41GlySer: 5.41 ± 0.075
5.427GlyThr: 5.427 ± 0.074
8.006GlyVal: 8.006 ± 0.083
1.748GlyTrp: 1.748 ± 0.041
2.316GlyTyr: 2.316 ± 0.04
0.0GlyXaa: 0.0 ± 0.0
His
2.394HisAla: 2.394 ± 0.048
0.106HisCys: 0.106 ± 0.01
1.38HisAsp: 1.38 ± 0.034
1.247HisGlu: 1.247 ± 0.031
0.622HisPhe: 0.622 ± 0.022
2.065HisGly: 2.065 ± 0.045
0.541HisHis: 0.541 ± 0.022
0.66HisIle: 0.66 ± 0.022
0.235HisLys: 0.235 ± 0.013
2.035HisLeu: 2.035 ± 0.047
0.269HisMet: 0.269 ± 0.015
0.357HisAsn: 0.357 ± 0.019
1.544HisPro: 1.544 ± 0.037
0.466HisGln: 0.466 ± 0.021
1.619HisArg: 1.619 ± 0.04
1.014HisSer: 1.014 ± 0.03
0.915HisThr: 0.915 ± 0.025
1.767HisVal: 1.767 ± 0.039
0.344HisTrp: 0.344 ± 0.018
0.456HisTyr: 0.456 ± 0.018
0.0HisXaa: 0.0 ± 0.0
Ile
7.258IleAla: 7.258 ± 0.085
0.234IleCys: 0.234 ± 0.014
3.601IleAsp: 3.601 ± 0.05
3.297IleGlu: 3.297 ± 0.059
1.213IlePhe: 1.213 ± 0.037
4.758IleGly: 4.758 ± 0.073
0.652IleHis: 0.652 ± 0.026
1.813IleIle: 1.813 ± 0.046
0.682IleLys: 0.682 ± 0.026
3.422IleLeu: 3.422 ± 0.06
0.631IleMet: 0.631 ± 0.029
0.873IleAsn: 0.873 ± 0.023
2.308IlePro: 2.308 ± 0.04
0.878IleGln: 0.878 ± 0.028
2.844IleArg: 2.844 ± 0.052
2.347IleSer: 2.347 ± 0.044
2.773IleThr: 2.773 ± 0.052
4.788IleVal: 4.788 ± 0.071
0.521IleTrp: 0.521 ± 0.022
0.791IleTyr: 0.791 ± 0.025
0.0IleXaa: 0.0 ± 0.0
Lys
2.171LysAla: 2.171 ± 0.051
0.056LysCys: 0.056 ± 0.007
0.846LysAsp: 0.846 ± 0.03
0.843LysGlu: 0.843 ± 0.03
0.462LysPhe: 0.462 ± 0.02
1.39LysGly: 1.39 ± 0.04
0.443LysHis: 0.443 ± 0.019
0.782LysIle: 0.782 ± 0.026
0.535LysLys: 0.535 ± 0.027
1.793LysLeu: 1.793 ± 0.042
0.302LysMet: 0.302 ± 0.014
0.424LysAsn: 0.424 ± 0.019
1.172LysPro: 1.172 ± 0.031
0.617LysGln: 0.617 ± 0.022
1.458LysArg: 1.458 ± 0.036
1.03LysSer: 1.03 ± 0.028
1.123LysThr: 1.123 ± 0.035
1.535LysVal: 1.535 ± 0.043
0.244LysTrp: 0.244 ± 0.016
0.379LysTyr: 0.379 ± 0.014
0.0LysXaa: 0.0 ± 0.0
Leu
15.011LeuAla: 15.011 ± 0.131
0.448LeuCys: 0.448 ± 0.019
6.971LeuAsp: 6.971 ± 0.079
6.039LeuGlu: 6.039 ± 0.07
2.905LeuPhe: 2.905 ± 0.062
9.426LeuGly: 9.426 ± 0.098
1.87LeuHis: 1.87 ± 0.039
4.426LeuIle: 4.426 ± 0.075
1.6LeuLys: 1.6 ± 0.04
9.86LeuLeu: 9.86 ± 0.112
1.506LeuMet: 1.506 ± 0.035
1.81LeuAsn: 1.81 ± 0.036
5.413LeuPro: 5.413 ± 0.059
2.35LeuGln: 2.35 ± 0.04
7.006LeuArg: 7.006 ± 0.074
5.492LeuSer: 5.492 ± 0.061
5.843LeuThr: 5.843 ± 0.071
9.552LeuVal: 9.552 ± 0.094
1.21LeuTrp: 1.21 ± 0.031
1.681LeuTyr: 1.681 ± 0.04
0.0LeuXaa: 0.0 ± 0.0
Met
2.024MetAla: 2.024 ± 0.043
0.079MetCys: 0.079 ± 0.008
0.7MetAsp: 0.7 ± 0.021
0.632MetGlu: 0.632 ± 0.024
0.548MetPhe: 0.548 ± 0.017
1.188MetGly: 1.188 ± 0.032
0.372MetHis: 0.372 ± 0.017
0.807MetIle: 0.807 ± 0.026
0.385MetLys: 0.385 ± 0.019
1.904MetLeu: 1.904 ± 0.039
0.292MetMet: 0.292 ± 0.014
0.467MetAsn: 0.467 ± 0.021
1.264MetPro: 1.264 ± 0.029
0.567MetGln: 0.567 ± 0.019
1.404MetArg: 1.404 ± 0.033
1.331MetSer: 1.331 ± 0.033
1.57MetThr: 1.57 ± 0.028
1.284MetVal: 1.284 ± 0.032
0.212MetTrp: 0.212 ± 0.015
0.272MetTyr: 0.272 ± 0.015
0.0MetXaa: 0.0 ± 0.0
Asn
2.48AsnAla: 2.48 ± 0.045
0.111AsnCys: 0.111 ± 0.009
1.192AsnAsp: 1.192 ± 0.032
1.083AsnGlu: 1.083 ± 0.03
0.663AsnPhe: 0.663 ± 0.023
2.034AsnGly: 2.034 ± 0.047
0.414AsnHis: 0.414 ± 0.019
0.863AsnIle: 0.863 ± 0.027
0.33AsnLys: 0.33 ± 0.016
1.861AsnLeu: 1.861 ± 0.04
0.299AsnMet: 0.299 ± 0.018
0.445AsnAsn: 0.445 ± 0.021
1.605AsnPro: 1.605 ± 0.038
0.535AsnGln: 0.535 ± 0.02
1.313AsnArg: 1.313 ± 0.029
1.022AsnSer: 1.022 ± 0.032
1.171AsnThr: 1.171 ± 0.034
1.704AsnVal: 1.704 ± 0.04
0.346AsnTrp: 0.346 ± 0.017
0.466AsnTyr: 0.466 ± 0.023
0.0AsnXaa: 0.0 ± 0.0
Pro
7.315ProAla: 7.315 ± 0.089
0.183ProCys: 0.183 ± 0.01
3.952ProAsp: 3.952 ± 0.064
4.065ProGlu: 4.065 ± 0.058
1.816ProPhe: 1.816 ± 0.037
5.229ProGly: 5.229 ± 0.077
1.025ProHis: 1.025 ± 0.03
2.338ProIle: 2.338 ± 0.047
1.016ProLys: 1.016 ± 0.027
4.828ProLeu: 4.828 ± 0.064
0.919ProMet: 0.919 ± 0.024
1.174ProAsn: 1.174 ± 0.032
2.512ProPro: 2.512 ± 0.055
1.327ProGln: 1.327 ± 0.03
3.42ProArg: 3.42 ± 0.058
3.218ProSer: 3.218 ± 0.049
3.305ProThr: 3.305 ± 0.056
4.896ProVal: 4.896 ± 0.07
0.907ProTrp: 0.907 ± 0.026
1.09ProTyr: 1.09 ± 0.028
0.0ProXaa: 0.0 ± 0.0
Gln
3.245GlnAla: 3.245 ± 0.045
0.102GlnCys: 0.102 ± 0.009
1.024GlnAsp: 1.024 ± 0.027
1.216GlnGlu: 1.216 ± 0.032
0.915GlnPhe: 0.915 ± 0.027
1.88GlnGly: 1.88 ± 0.04
0.604GlnHis: 0.604 ± 0.023
1.144GlnIle: 1.144 ± 0.035
0.507GlnLys: 0.507 ± 0.023
3.114GlnLeu: 3.114 ± 0.045
0.437GlnMet: 0.437 ± 0.018
0.593GlnAsn: 0.593 ± 0.023
1.518GlnPro: 1.518 ± 0.032
1.058GlnGln: 1.058 ± 0.034
2.266GlnArg: 2.266 ± 0.042
1.467GlnSer: 1.467 ± 0.036
1.348GlnThr: 1.348 ± 0.033
2.194GlnVal: 2.194 ± 0.046
0.416GlnTrp: 0.416 ± 0.017
0.583GlnTyr: 0.583 ± 0.02
0.0GlnXaa: 0.0 ± 0.0
Arg
9.015ArgAla: 9.015 ± 0.101
0.329ArgCys: 0.329 ± 0.016
4.13ArgAsp: 4.13 ± 0.056
4.556ArgGlu: 4.556 ± 0.076
2.605ArgPhe: 2.605 ± 0.047
5.545ArgGly: 5.545 ± 0.075
1.681ArgHis: 1.681 ± 0.038
3.718ArgIle: 3.718 ± 0.056
1.233ArgLys: 1.233 ± 0.034
7.54ArgLeu: 7.54 ± 0.099
1.749ArgMet: 1.749 ± 0.036
1.439ArgAsn: 1.439 ± 0.035
3.822ArgPro: 3.822 ± 0.066
1.915ArgGln: 1.915 ± 0.043
6.694ArgArg: 6.694 ± 0.092
4.397ArgSer: 4.397 ± 0.065
3.96ArgThr: 3.96 ± 0.054
6.074ArgVal: 6.074 ± 0.07
1.191ArgTrp: 1.191 ± 0.03
1.65ArgTyr: 1.65 ± 0.033
0.0ArgXaa: 0.0 ± 0.0
Ser
7.149SerAla: 7.149 ± 0.078
0.285SerCys: 0.285 ± 0.018
3.252SerAsp: 3.252 ± 0.06
2.933SerGlu: 2.933 ± 0.046
1.972SerPhe: 1.972 ± 0.038
5.957SerGly: 5.957 ± 0.089
1.02SerHis: 1.02 ± 0.03
2.738SerIle: 2.738 ± 0.042
1.072SerLys: 1.072 ± 0.032
5.453SerLeu: 5.453 ± 0.067
1.153SerMet: 1.153 ± 0.032
1.208SerAsn: 1.208 ± 0.034
3.265SerPro: 3.265 ± 0.048
1.359SerGln: 1.359 ± 0.036
3.921SerArg: 3.921 ± 0.06
3.458SerSer: 3.458 ± 0.061
3.65SerThr: 3.65 ± 0.064
5.022SerVal: 5.022 ± 0.067
0.927SerTrp: 0.927 ± 0.03
1.227SerTyr: 1.227 ± 0.033
0.0SerXaa: 0.0 ± 0.0
Thr
7.575ThrAla: 7.575 ± 0.08
0.283ThrCys: 0.283 ± 0.021
3.571ThrAsp: 3.571 ± 0.053
3.151ThrGlu: 3.151 ± 0.053
1.968ThrPhe: 1.968 ± 0.044
5.708ThrGly: 5.708 ± 0.071
1.073ThrHis: 1.073 ± 0.029
3.014ThrIle: 3.014 ± 0.056
1.098ThrLys: 1.098 ± 0.031
5.642ThrLeu: 5.642 ± 0.068
0.969ThrMet: 0.969 ± 0.026
1.203ThrAsn: 1.203 ± 0.032
3.691ThrPro: 3.691 ± 0.051
1.314ThrGln: 1.314 ± 0.031
3.6ThrArg: 3.6 ± 0.057
3.443ThrSer: 3.443 ± 0.058
3.784ThrThr: 3.784 ± 0.072
5.526ThrVal: 5.526 ± 0.075
0.916ThrTrp: 0.916 ± 0.029
1.068ThrTyr: 1.068 ± 0.031
0.0ThrXaa: 0.0 ± 0.0
Val
11.872ValAla: 11.872 ± 0.111
0.455ValCys: 0.455 ± 0.02
5.828ValAsp: 5.828 ± 0.076
5.279ValGlu: 5.279 ± 0.065
3.038ValPhe: 3.038 ± 0.052
7.048ValGly: 7.048 ± 0.083
1.759ValHis: 1.759 ± 0.033
4.343ValIle: 4.343 ± 0.063
1.504ValLys: 1.504 ± 0.041
9.369ValLeu: 9.369 ± 0.097
1.366ValMet: 1.366 ± 0.033
1.833ValAsn: 1.833 ± 0.043
4.882ValPro: 4.882 ± 0.056
2.175ValGln: 2.175 ± 0.045
6.214ValArg: 6.214 ± 0.076
4.926ValSer: 4.926 ± 0.073
5.614ValThr: 5.614 ± 0.079
8.651ValVal: 8.651 ± 0.105
1.152ValTrp: 1.152 ± 0.031
1.57ValTyr: 1.57 ± 0.039
0.0ValXaa: 0.0 ± 0.0
Trp
1.649TrpAla: 1.649 ± 0.035
0.09TrpCys: 0.09 ± 0.008
0.799TrpAsp: 0.799 ± 0.026
0.687TrpGlu: 0.687 ± 0.02
0.621TrpPhe: 0.621 ± 0.022
1.104TrpGly: 1.104 ± 0.03
0.371TrpHis: 0.371 ± 0.016
0.762TrpIle: 0.762 ± 0.023
0.315TrpLys: 0.315 ± 0.016
1.85TrpLeu: 1.85 ± 0.042
0.354TrpMet: 0.354 ± 0.017
0.483TrpAsn: 0.483 ± 0.02
0.772TrpPro: 0.772 ± 0.025
0.557TrpGln: 0.557 ± 0.021
1.273TrpArg: 1.273 ± 0.03
1.08TrpSer: 1.08 ± 0.038
0.903TrpThr: 0.903 ± 0.031
1.158TrpVal: 1.158 ± 0.032
0.381TrpTrp: 0.381 ± 0.018
0.336TrpTyr: 0.336 ± 0.017
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.415TyrAla: 2.415 ± 0.047
0.115TyrCys: 0.115 ± 0.009
1.367TyrAsp: 1.367 ± 0.034
1.204TyrGlu: 1.204 ± 0.033
0.76TyrPhe: 0.76 ± 0.026
1.918TyrGly: 1.918 ± 0.042
0.348TyrHis: 0.348 ± 0.015
0.618TyrIle: 0.618 ± 0.021
0.3TyrLys: 0.3 ± 0.016
2.224TyrLeu: 2.224 ± 0.045
0.253TyrMet: 0.253 ± 0.015
0.473TyrAsn: 0.473 ± 0.021
1.042TyrPro: 1.042 ± 0.027
0.527TyrGln: 0.527 ± 0.023
1.736TyrArg: 1.736 ± 0.041
1.135TyrSer: 1.135 ± 0.033
1.172TyrThr: 1.172 ± 0.032
1.633TyrVal: 1.633 ± 0.03
0.351TyrTrp: 0.351 ± 0.018
0.499TyrTyr: 0.499 ± 0.02
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3965 proteins (1288838 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski