Amino acid dipepetide frequency for Myxoma virus (strain Lausanne) (MYXV)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.727AlaAla: 2.727 ± 0.269
1.219AlaCys: 1.219 ± 0.182
2.665AlaAsp: 2.665 ± 0.246
2.128AlaGlu: 2.128 ± 0.225
2.066AlaPhe: 2.066 ± 0.223
1.859AlaGly: 1.859 ± 0.243
0.847AlaHis: 0.847 ± 0.144
3.305AlaIle: 3.305 ± 0.221
2.644AlaLys: 2.644 ± 0.21
4.628AlaLeu: 4.628 ± 0.315
1.095AlaMet: 1.095 ± 0.16
2.314AlaAsn: 2.314 ± 0.211
1.301AlaPro: 1.301 ± 0.165
0.599AlaGln: 0.599 ± 0.117
2.21AlaArg: 2.21 ± 0.209
3.76AlaSer: 3.76 ± 0.272
3.264AlaThr: 3.264 ± 0.249
4.07AlaVal: 4.07 ± 0.354
0.31AlaTrp: 0.31 ± 0.083
2.252AlaTyr: 2.252 ± 0.263
0.0AlaXaa: 0.0 ± 0.0
Cys
0.992CysAla: 0.992 ± 0.146
0.62CysCys: 0.62 ± 0.101
1.26CysAsp: 1.26 ± 0.147
1.012CysGlu: 1.012 ± 0.151
0.93CysPhe: 0.93 ± 0.15
0.806CysGly: 0.806 ± 0.143
0.372CysHis: 0.372 ± 0.078
1.797CysIle: 1.797 ± 0.19
1.508CysLys: 1.508 ± 0.17
1.797CysLeu: 1.797 ± 0.222
0.454CysMet: 0.454 ± 0.099
1.033CysAsn: 1.033 ± 0.145
0.806CysPro: 0.806 ± 0.146
0.289CysGln: 0.289 ± 0.077
1.033CysArg: 1.033 ± 0.149
1.715CysSer: 1.715 ± 0.197
1.487CysThr: 1.487 ± 0.204
2.107CysVal: 2.107 ± 0.242
0.207CysTrp: 0.207 ± 0.07
1.26CysTyr: 1.26 ± 0.147
0.0CysXaa: 0.0 ± 0.0
Asp
3.657AspAla: 3.657 ± 0.302
0.847AspCys: 0.847 ± 0.131
5.103AspAsp: 5.103 ± 0.36
4.338AspGlu: 4.338 ± 0.3
2.686AspPhe: 2.686 ± 0.232
2.851AspGly: 2.851 ± 0.226
0.661AspHis: 0.661 ± 0.116
5.413AspIle: 5.413 ± 0.421
3.842AspLys: 3.842 ± 0.347
4.669AspLeu: 4.669 ± 0.352
1.446AspMet: 1.446 ± 0.196
2.789AspAsn: 2.789 ± 0.237
2.169AspPro: 2.169 ± 0.215
0.826AspGln: 0.826 ± 0.12
2.52AspArg: 2.52 ± 0.232
3.615AspSer: 3.615 ± 0.283
3.801AspThr: 3.801 ± 0.305
7.024AspVal: 7.024 ± 0.387
0.351AspTrp: 0.351 ± 0.085
3.099AspTyr: 3.099 ± 0.254
0.0AspXaa: 0.0 ± 0.0
Glu
2.21GluAla: 2.21 ± 0.236
1.219GluCys: 1.219 ± 0.18
3.946GluAsp: 3.946 ± 0.295
4.669GluGlu: 4.669 ± 0.53
2.417GluPhe: 2.417 ± 0.235
1.859GluGly: 1.859 ± 0.19
1.405GluHis: 1.405 ± 0.18
3.966GluIle: 3.966 ± 0.321
3.966GluLys: 3.966 ± 0.26
5.722GluLeu: 5.722 ± 0.342
1.033GluMet: 1.033 ± 0.129
2.934GluAsn: 2.934 ± 0.227
1.983GluPro: 1.983 ± 0.231
1.26GluGln: 1.26 ± 0.16
2.913GluArg: 2.913 ± 0.243
3.739GluSer: 3.739 ± 0.293
3.574GluThr: 3.574 ± 0.279
2.995GluVal: 2.995 ± 0.273
0.475GluTrp: 0.475 ± 0.105
3.429GluTyr: 3.429 ± 0.244
0.0GluXaa: 0.0 ± 0.0
Phe
1.508PheAla: 1.508 ± 0.186
1.033PheCys: 1.033 ± 0.163
3.119PheAsp: 3.119 ± 0.265
2.231PheGlu: 2.231 ± 0.196
2.541PhePhe: 2.541 ± 0.222
2.087PheGly: 2.087 ± 0.2
0.847PheHis: 0.847 ± 0.122
4.338PheIle: 4.338 ± 0.316
3.615PheLys: 3.615 ± 0.297
4.628PheLeu: 4.628 ± 0.345
1.508PheMet: 1.508 ± 0.207
3.202PheAsn: 3.202 ± 0.298
1.508PhePro: 1.508 ± 0.194
0.868PheGln: 0.868 ± 0.131
1.632PheArg: 1.632 ± 0.183
3.657PheSer: 3.657 ± 0.294
3.243PheThr: 3.243 ± 0.23
4.214PheVal: 4.214 ± 0.291
0.393PheTrp: 0.393 ± 0.1
2.19PheTyr: 2.19 ± 0.19
0.0PheXaa: 0.0 ± 0.0
Gly
2.128GlyAla: 2.128 ± 0.264
1.054GlyCys: 1.054 ± 0.176
2.624GlyAsp: 2.624 ± 0.255
1.591GlyGlu: 1.591 ± 0.158
1.735GlyPhe: 1.735 ± 0.209
2.748GlyGly: 2.748 ± 0.366
0.723GlyHis: 0.723 ± 0.112
3.367GlyIle: 3.367 ± 0.265
2.954GlyLys: 2.954 ± 0.251
2.934GlyLeu: 2.934 ± 0.257
0.95GlyMet: 0.95 ± 0.14
2.417GlyAsn: 2.417 ± 0.248
1.054GlyPro: 1.054 ± 0.152
0.806GlyGln: 0.806 ± 0.129
2.293GlyArg: 2.293 ± 0.226
2.582GlySer: 2.582 ± 0.253
3.037GlyThr: 3.037 ± 0.26
3.553GlyVal: 3.553 ± 0.264
0.372GlyTrp: 0.372 ± 0.086
2.644GlyTyr: 2.644 ± 0.243
0.0GlyXaa: 0.0 ± 0.0
His
1.033HisAla: 1.033 ± 0.149
0.351HisCys: 0.351 ± 0.102
1.198HisAsp: 1.198 ± 0.14
1.136HisGlu: 1.136 ± 0.152
0.888HisPhe: 0.888 ± 0.122
1.198HisGly: 1.198 ± 0.154
0.434HisHis: 0.434 ± 0.097
1.467HisIle: 1.467 ± 0.176
1.859HisLys: 1.859 ± 0.206
2.066HisLeu: 2.066 ± 0.201
0.806HisMet: 0.806 ± 0.148
1.487HisAsn: 1.487 ± 0.187
0.992HisPro: 0.992 ± 0.145
0.475HisGln: 0.475 ± 0.1
1.116HisArg: 1.116 ± 0.127
1.322HisSer: 1.322 ± 0.147
1.384HisThr: 1.384 ± 0.188
2.231HisVal: 2.231 ± 0.214
0.207HisTrp: 0.207 ± 0.057
0.95HisTyr: 0.95 ± 0.14
0.0HisXaa: 0.0 ± 0.0
Ile
3.161IleAla: 3.161 ± 0.265
1.178IleCys: 1.178 ± 0.15
4.69IleAsp: 4.69 ± 0.277
4.028IleGlu: 4.028 ± 0.279
3.347IlePhe: 3.347 ± 0.293
2.851IleGly: 2.851 ± 0.249
2.376IleHis: 2.376 ± 0.222
5.64IleIle: 5.64 ± 0.442
6.776IleLys: 6.776 ± 0.416
7.313IleLeu: 7.313 ± 0.384
1.549IleMet: 1.549 ± 0.148
5.082IleAsn: 5.082 ± 0.336
2.541IlePro: 2.541 ± 0.278
2.087IleGln: 2.087 ± 0.219
3.884IleArg: 3.884 ± 0.332
5.64IleSer: 5.64 ± 0.37
4.669IleThr: 4.669 ± 0.298
5.371IleVal: 5.371 ± 0.365
0.558IleTrp: 0.558 ± 0.119
3.388IleTyr: 3.388 ± 0.292
0.0IleXaa: 0.0 ± 0.0
Lys
3.202LysAla: 3.202 ± 0.258
1.405LysCys: 1.405 ± 0.193
4.09LysAsp: 4.09 ± 0.31
4.235LysGlu: 4.235 ± 0.318
2.665LysPhe: 2.665 ± 0.324
2.851LysGly: 2.851 ± 0.24
2.417LysHis: 2.417 ± 0.214
5.991LysIle: 5.991 ± 0.408
6.879LysLys: 6.879 ± 0.387
6.755LysLeu: 6.755 ± 0.362
2.004LysMet: 2.004 ± 0.205
4.648LysAsn: 4.648 ± 0.307
2.045LysPro: 2.045 ± 0.182
2.52LysGln: 2.52 ± 0.246
3.987LysArg: 3.987 ± 0.303
4.628LysSer: 4.628 ± 0.345
5.475LysThr: 5.475 ± 0.272
4.132LysVal: 4.132 ± 0.249
0.331LysTrp: 0.331 ± 0.079
4.028LysTyr: 4.028 ± 0.322
0.0LysXaa: 0.0 ± 0.0
Leu
3.904LeuAla: 3.904 ± 0.269
2.148LeuCys: 2.148 ± 0.194
5.392LeuAsp: 5.392 ± 0.377
4.937LeuGlu: 4.937 ± 0.326
4.937LeuPhe: 4.937 ± 0.354
3.533LeuGly: 3.533 ± 0.304
1.983LeuHis: 1.983 ± 0.2
5.867LeuIle: 5.867 ± 0.332
6.673LeuLys: 6.673 ± 0.358
8.697LeuLeu: 8.697 ± 0.47
2.025LeuMet: 2.025 ± 0.226
5.433LeuAsn: 5.433 ± 0.263
3.078LeuPro: 3.078 ± 0.255
2.603LeuGln: 2.603 ± 0.236
4.318LeuArg: 4.318 ± 0.335
7.375LeuSer: 7.375 ± 0.372
6.094LeuThr: 6.094 ± 0.367
6.053LeuVal: 6.053 ± 0.323
0.578LeuTrp: 0.578 ± 0.126
4.937LeuTyr: 4.937 ± 0.36
0.0LeuXaa: 0.0 ± 0.0
Met
1.301MetAla: 1.301 ± 0.179
0.351MetCys: 0.351 ± 0.097
1.673MetAsp: 1.673 ± 0.206
1.715MetGlu: 1.715 ± 0.187
1.467MetPhe: 1.467 ± 0.184
0.826MetGly: 0.826 ± 0.132
0.413MetHis: 0.413 ± 0.096
1.818MetIle: 1.818 ± 0.176
1.549MetLys: 1.549 ± 0.189
2.148MetLeu: 2.148 ± 0.202
0.372MetMet: 0.372 ± 0.089
1.26MetAsn: 1.26 ± 0.17
0.826MetPro: 0.826 ± 0.135
0.475MetGln: 0.475 ± 0.099
1.054MetArg: 1.054 ± 0.159
2.045MetSer: 2.045 ± 0.219
1.26MetThr: 1.26 ± 0.145
1.343MetVal: 1.343 ± 0.153
0.083MetTrp: 0.083 ± 0.039
1.591MetTyr: 1.591 ± 0.178
0.0MetXaa: 0.0 ± 0.0
Asn
2.81AsnAla: 2.81 ± 0.237
0.909AsnCys: 0.909 ± 0.141
3.884AsnAsp: 3.884 ± 0.246
3.595AsnGlu: 3.595 ± 0.297
2.376AsnPhe: 2.376 ± 0.188
2.644AsnGly: 2.644 ± 0.249
1.24AsnHis: 1.24 ± 0.174
4.772AsnIle: 4.772 ± 0.355
4.958AsnLys: 4.958 ± 0.321
3.946AsnLeu: 3.946 ± 0.296
1.591AsnMet: 1.591 ± 0.205
3.904AsnAsn: 3.904 ± 0.355
2.334AsnPro: 2.334 ± 0.294
1.012AsnGln: 1.012 ± 0.134
1.983AsnArg: 1.983 ± 0.184
3.14AsnSer: 3.14 ± 0.268
4.049AsnThr: 4.049 ± 0.3
5.413AsnVal: 5.413 ± 0.363
0.372AsnTrp: 0.372 ± 0.084
2.892AsnTyr: 2.892 ± 0.27
0.0AsnXaa: 0.0 ± 0.0
Pro
1.136ProAla: 1.136 ± 0.166
0.806ProCys: 0.806 ± 0.131
2.169ProAsp: 2.169 ± 0.216
2.376ProGlu: 2.376 ± 0.219
1.901ProPhe: 1.901 ± 0.183
1.508ProGly: 1.508 ± 0.196
0.744ProHis: 0.744 ± 0.118
2.582ProIle: 2.582 ± 0.283
2.376ProLys: 2.376 ± 0.247
3.347ProLeu: 3.347 ± 0.265
0.62ProMet: 0.62 ± 0.108
2.128ProAsn: 2.128 ± 0.182
1.735ProPro: 1.735 ± 0.21
0.62ProGln: 0.62 ± 0.115
1.756ProArg: 1.756 ± 0.188
2.872ProSer: 2.872 ± 0.238
2.644ProThr: 2.644 ± 0.217
2.355ProVal: 2.355 ± 0.252
0.248ProTrp: 0.248 ± 0.084
1.756ProTyr: 1.756 ± 0.184
0.0ProXaa: 0.0 ± 0.0
Gln
0.868GlnAla: 0.868 ± 0.145
0.558GlnCys: 0.558 ± 0.105
1.24GlnAsp: 1.24 ± 0.143
1.322GlnGlu: 1.322 ± 0.177
0.785GlnPhe: 0.785 ± 0.131
0.826GlnGly: 0.826 ± 0.125
0.454GlnHis: 0.454 ± 0.099
1.632GlnIle: 1.632 ± 0.193
2.128GlnLys: 2.128 ± 0.23
2.293GlnLeu: 2.293 ± 0.204
0.496GlnMet: 0.496 ± 0.104
1.012GlnAsn: 1.012 ± 0.12
1.012GlnPro: 1.012 ± 0.137
0.64GlnGln: 0.64 ± 0.13
1.508GlnArg: 1.508 ± 0.172
1.487GlnSer: 1.487 ± 0.154
1.487GlnThr: 1.487 ± 0.196
1.033GlnVal: 1.033 ± 0.177
0.289GlnTrp: 0.289 ± 0.074
1.033GlnTyr: 1.033 ± 0.145
0.0GlnXaa: 0.0 ± 0.0
Arg
1.777ArgAla: 1.777 ± 0.241
1.198ArgCys: 1.198 ± 0.18
2.624ArgAsp: 2.624 ± 0.307
1.963ArgGlu: 1.963 ± 0.197
2.768ArgPhe: 2.768 ± 0.235
2.004ArgGly: 2.004 ± 0.236
1.322ArgHis: 1.322 ± 0.156
3.326ArgIle: 3.326 ± 0.238
2.748ArgLys: 2.748 ± 0.233
4.875ArgLeu: 4.875 ± 0.266
1.054ArgMet: 1.054 ± 0.164
2.458ArgAsn: 2.458 ± 0.251
1.57ArgPro: 1.57 ± 0.177
1.281ArgGln: 1.281 ± 0.158
2.892ArgArg: 2.892 ± 0.224
2.83ArgSer: 2.83 ± 0.22
3.243ArgThr: 3.243 ± 0.278
3.657ArgVal: 3.657 ± 0.28
0.558ArgTrp: 0.558 ± 0.125
2.892ArgTyr: 2.892 ± 0.32
0.021ArgXaa: 0.021 ± 0.02
Ser
3.429SerAla: 3.429 ± 0.267
1.363SerCys: 1.363 ± 0.183
4.359SerAsp: 4.359 ± 0.344
3.595SerGlu: 3.595 ± 0.266
3.781SerPhe: 3.781 ± 0.287
2.954SerGly: 2.954 ± 0.248
1.446SerHis: 1.446 ± 0.189
5.557SerIle: 5.557 ± 0.361
4.958SerLys: 4.958 ± 0.323
6.115SerLeu: 6.115 ± 0.367
1.839SerMet: 1.839 ± 0.211
3.863SerAsn: 3.863 ± 0.297
2.81SerPro: 2.81 ± 0.236
1.632SerGln: 1.632 ± 0.185
3.016SerArg: 3.016 ± 0.228
5.454SerSer: 5.454 ± 0.485
4.545SerThr: 4.545 ± 0.421
6.032SerVal: 6.032 ± 0.41
0.454SerTrp: 0.454 ± 0.085
3.781SerTyr: 3.781 ± 0.296
0.0SerXaa: 0.0 ± 0.0
Thr
3.016ThrAla: 3.016 ± 0.248
1.653ThrCys: 1.653 ± 0.186
3.946ThrAsp: 3.946 ± 0.299
3.822ThrGlu: 3.822 ± 0.304
3.657ThrPhe: 3.657 ± 0.254
2.582ThrGly: 2.582 ± 0.246
1.715ThrHis: 1.715 ± 0.239
4.834ThrIle: 4.834 ± 0.331
4.751ThrLys: 4.751 ± 0.336
6.198ThrLeu: 6.198 ± 0.352
1.57ThrMet: 1.57 ± 0.179
3.533ThrAsn: 3.533 ± 0.269
2.789ThrPro: 2.789 ± 0.23
1.281ThrGln: 1.281 ± 0.148
2.789ThrArg: 2.789 ± 0.235
4.999ThrSer: 4.999 ± 0.335
4.173ThrThr: 4.173 ± 0.317
5.309ThrVal: 5.309 ± 0.382
0.702ThrTrp: 0.702 ± 0.132
3.491ThrTyr: 3.491 ± 0.277
0.021ThrXaa: 0.021 ± 0.02
Val
3.553ValAla: 3.553 ± 0.255
2.231ValCys: 2.231 ± 0.181
4.4ValAsp: 4.4 ± 0.325
4.111ValGlu: 4.111 ± 0.306
4.214ValPhe: 4.214 ± 0.339
2.334ValGly: 2.334 ± 0.246
1.921ValHis: 1.921 ± 0.226
5.041ValIle: 5.041 ± 0.312
5.516ValLys: 5.516 ± 0.345
6.983ValLeu: 6.983 ± 0.383
1.384ValMet: 1.384 ± 0.149
4.731ValAsn: 4.731 ± 0.28
3.078ValPro: 3.078 ± 0.256
1.839ValGln: 1.839 ± 0.2
3.946ValArg: 3.946 ± 0.334
6.218ValSer: 6.218 ± 0.394
5.392ValThr: 5.392 ± 0.39
6.115ValVal: 6.115 ± 0.464
0.248ValTrp: 0.248 ± 0.074
4.731ValTyr: 4.731 ± 0.378
0.021ValXaa: 0.021 ± 0.02
Trp
0.289TrpAla: 0.289 ± 0.098
0.124TrpCys: 0.124 ± 0.05
0.207TrpAsp: 0.207 ± 0.062
0.434TrpGlu: 0.434 ± 0.099
0.496TrpPhe: 0.496 ± 0.111
0.351TrpGly: 0.351 ± 0.073
0.227TrpHis: 0.227 ± 0.054
0.806TrpIle: 0.806 ± 0.127
0.62TrpLys: 0.62 ± 0.108
0.558TrpLeu: 0.558 ± 0.106
0.269TrpMet: 0.269 ± 0.065
0.269TrpAsn: 0.269 ± 0.084
0.227TrpPro: 0.227 ± 0.062
0.124TrpGln: 0.124 ± 0.051
0.516TrpArg: 0.516 ± 0.111
0.434TrpSer: 0.434 ± 0.096
0.537TrpThr: 0.537 ± 0.134
0.393TrpVal: 0.393 ± 0.101
0.041TrpTrp: 0.041 ± 0.026
0.351TrpTyr: 0.351 ± 0.085
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.562TyrAla: 2.562 ± 0.262
1.219TyrCys: 1.219 ± 0.158
3.119TyrAsp: 3.119 ± 0.238
2.479TyrGlu: 2.479 ± 0.25
2.727TyrPhe: 2.727 ± 0.204
2.872TyrGly: 2.872 ± 0.253
1.033TyrHis: 1.033 ± 0.148
4.607TyrIle: 4.607 ± 0.319
3.966TyrLys: 3.966 ± 0.262
4.896TyrLeu: 4.896 ± 0.346
1.487TyrMet: 1.487 ± 0.195
3.326TyrAsn: 3.326 ± 0.316
1.818TyrPro: 1.818 ± 0.189
0.868TyrGln: 0.868 ± 0.117
1.694TyrArg: 1.694 ± 0.179
3.471TyrSer: 3.471 ± 0.217
3.471TyrThr: 3.471 ± 0.283
4.586TyrVal: 4.586 ± 0.314
0.496TyrTrp: 0.496 ± 0.108
2.231TyrTyr: 2.231 ± 0.257
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.021XaaGly: 0.021 ± 0.02
0.021XaaHis: 0.021 ± 0.02
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.021XaaVal: 0.021 ± 0.02
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 158 proteins (48407 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski