Amino acid dipepetide frequency for Pteropus associated gemycircularvirus 8

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
3.567AlaAla: 3.567 ± 0.41
0.0AlaCys: 0.0 ± 0.0
3.567AlaAsp: 3.567 ± 1.654
7.134AlaGlu: 7.134 ± 3.309
0.0AlaPhe: 0.0 ± 0.0
5.945AlaGly: 5.945 ± 1.837
0.0AlaHis: 0.0 ± 0.0
4.756AlaIle: 4.756 ± 0.943
4.756AlaLys: 4.756 ± 0.943
4.756AlaLeu: 4.756 ± 2.203
3.567AlaMet: 3.567 ± 1.127
5.945AlaAsn: 5.945 ± 0.339
9.512AlaPro: 9.512 ± 1.698
2.378AlaGln: 2.378 ± 0.717
3.567AlaArg: 3.567 ± 1.654
2.378AlaSer: 2.378 ± 1.879
8.323AlaThr: 8.323 ± 5.067
5.945AlaVal: 5.945 ± 0.339
0.0AlaTrp: 0.0 ± 0.0
2.378AlaTyr: 2.378 ± 1.102
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
0.0CysCys: 0.0 ± 0.0
2.378CysAsp: 2.378 ± 1.102
2.378CysGlu: 2.378 ± 1.879
1.189CysPhe: 1.189 ± 0.94
5.945CysGly: 5.945 ± 2.669
2.378CysHis: 2.378 ± 1.102
3.567CysIle: 3.567 ± 1.654
0.0CysLys: 0.0 ± 0.0
0.0CysLeu: 0.0 ± 0.0
0.0CysMet: 0.0 ± 0.876
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
0.0CysGln: 0.0 ± 0.0
0.0CysArg: 0.0 ± 0.0
0.0CysSer: 0.0 ± 0.0
2.378CysThr: 2.378 ± 1.102
0.0CysVal: 0.0 ± 0.0
0.0CysTrp: 0.0 ± 0.0
1.189CysTyr: 1.189 ± 0.94
0.0CysXaa: 0.0 ± 0.0
Asp
2.378AspAla: 2.378 ± 0.717
0.0AspCys: 0.0 ± 0.0
3.567AspAsp: 3.567 ± 1.419
1.189AspGlu: 1.189 ± 0.94
2.378AspPhe: 2.378 ± 1.102
11.891AspGly: 11.891 ± 3.898
2.378AspHis: 2.378 ± 1.102
1.189AspIle: 1.189 ± 0.883
2.378AspLys: 2.378 ± 1.879
7.134AspLeu: 7.134 ± 1.732
1.189AspMet: 1.189 ± 0.94
2.378AspAsn: 2.378 ± 1.879
4.756AspPro: 4.756 ± 2.412
2.378AspGln: 2.378 ± 1.102
2.378AspArg: 2.378 ± 1.102
3.567AspSer: 3.567 ± 0.41
4.756AspThr: 4.756 ± 0.737
7.134AspVal: 7.134 ± 3.305
2.378AspTrp: 2.378 ± 1.102
5.945AspTyr: 5.945 ± 0.339
0.0AspXaa: 0.0 ± 0.0
Glu
4.756GluAla: 4.756 ± 2.298
2.378GluCys: 2.378 ± 1.102
0.0GluAsp: 0.0 ± 0.0
4.756GluGlu: 4.756 ± 2.203
5.945GluPhe: 5.945 ± 2.669
1.189GluGly: 1.189 ± 0.883
0.0GluHis: 0.0 ± 0.0
1.189GluIle: 1.189 ± 0.94
1.189GluLys: 1.189 ± 0.94
3.567GluLeu: 3.567 ± 1.654
0.0GluMet: 0.0 ± 0.0
0.0GluAsn: 0.0 ± 0.0
0.0GluPro: 0.0 ± 0.0
1.189GluGln: 1.189 ± 0.94
2.378GluArg: 2.378 ± 1.102
2.378GluSer: 2.378 ± 1.102
3.567GluThr: 3.567 ± 0.41
0.0GluVal: 0.0 ± 0.0
2.378GluTrp: 2.378 ± 1.102
0.0GluTyr: 0.0 ± 0.0
0.0GluXaa: 0.0 ± 0.0
Phe
2.378PheAla: 2.378 ± 1.102
1.189PheCys: 1.189 ± 0.883
7.134PheAsp: 7.134 ± 1.732
0.0PheGlu: 0.0 ± 0.0
2.378PhePhe: 2.378 ± 0.717
2.378PheGly: 2.378 ± 1.102
1.189PheHis: 1.189 ± 0.883
5.945PheIle: 5.945 ± 1.837
2.378PheLys: 2.378 ± 0.717
0.0PheLeu: 0.0 ± 0.0
0.0PheMet: 0.0 ± 0.0
2.378PheAsn: 2.378 ± 1.879
2.378PhePro: 2.378 ± 1.102
2.378PheGln: 2.378 ± 0.717
1.189PheArg: 1.189 ± 0.94
4.756PheSer: 4.756 ± 2.203
1.189PheThr: 1.189 ± 0.883
3.567PheVal: 3.567 ± 1.654
2.378PheTrp: 2.378 ± 1.102
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
10.702GlyAla: 10.702 ± 1.759
0.0GlyCys: 0.0 ± 0.0
7.134GlyAsp: 7.134 ± 1.732
0.0GlyGlu: 0.0 ± 0.0
2.378GlyPhe: 2.378 ± 0.717
11.891GlyGly: 11.891 ± 1.038
2.378GlyHis: 2.378 ± 1.102
2.378GlyIle: 2.378 ± 0.717
2.378GlyLys: 2.378 ± 1.766
9.512GlyLeu: 9.512 ± 2.807
4.756GlyMet: 4.756 ± 2.618
7.134GlyAsn: 7.134 ± 1.205
3.567GlyPro: 3.567 ± 1.419
1.189GlyGln: 1.189 ± 0.94
9.512GlyArg: 9.512 ± 2.807
4.756GlySer: 4.756 ± 0.943
5.945GlyThr: 5.945 ± 1.371
1.189GlyVal: 1.189 ± 0.94
0.0GlyTrp: 0.0 ± 0.0
4.756GlyTyr: 4.756 ± 0.943
0.0GlyXaa: 0.0 ± 0.0
His
2.378HisAla: 2.378 ± 1.102
0.0HisCys: 0.0 ± 0.0
3.567HisAsp: 3.567 ± 1.654
1.189HisGlu: 1.189 ± 0.94
2.378HisPhe: 2.378 ± 1.102
3.567HisGly: 3.567 ± 1.306
2.378HisHis: 2.378 ± 1.102
1.189HisIle: 1.189 ± 0.883
0.0HisLys: 0.0 ± 0.0
2.378HisLeu: 2.378 ± 1.102
0.0HisMet: 0.0 ± 0.0
0.0HisAsn: 0.0 ± 0.0
2.378HisPro: 2.378 ± 1.102
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
2.378HisSer: 2.378 ± 1.102
0.0HisThr: 0.0 ± 0.0
2.378HisVal: 2.378 ± 1.102
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
4.756IleAla: 4.756 ± 0.943
2.378IleCys: 2.378 ± 1.879
2.378IleAsp: 2.378 ± 1.102
2.378IleGlu: 2.378 ± 1.102
1.189IlePhe: 1.189 ± 0.883
1.189IleGly: 1.189 ± 0.94
0.0IleHis: 0.0 ± 0.0
1.189IleIle: 1.189 ± 0.883
4.756IleLys: 4.756 ± 0.737
7.134IleLeu: 7.134 ± 1.732
1.189IleMet: 1.189 ± 0.94
1.189IleAsn: 1.189 ± 0.94
1.189IlePro: 1.189 ± 0.94
3.567IleGln: 3.567 ± 1.306
0.0IleArg: 0.0 ± 0.0
1.189IleSer: 1.189 ± 0.94
1.189IleThr: 1.189 ± 0.94
4.756IleVal: 4.756 ± 0.943
1.189IleTrp: 1.189 ± 0.883
2.378IleTyr: 2.378 ± 0.717
0.0IleXaa: 0.0 ± 0.0
Lys
5.945LysAla: 5.945 ± 1.837
2.378LysCys: 2.378 ± 1.102
3.567LysAsp: 3.567 ± 1.654
1.189LysGlu: 1.189 ± 0.94
1.189LysPhe: 1.189 ± 0.883
0.0LysGly: 0.0 ± 0.0
1.189LysHis: 1.189 ± 0.883
2.378LysIle: 2.378 ± 0.717
3.567LysLys: 3.567 ± 2.819
0.0LysLeu: 0.0 ± 0.0
1.189LysMet: 1.189 ± 0.768
4.756LysAsn: 4.756 ± 0.737
1.189LysPro: 1.189 ± 0.883
1.189LysGln: 1.189 ± 0.94
4.756LysArg: 4.756 ± 3.759
1.189LysSer: 1.189 ± 0.883
5.945LysThr: 5.945 ± 0.339
0.0LysVal: 0.0 ± 0.0
0.0LysTrp: 0.0 ± 0.0
7.134LysTyr: 7.134 ± 2.762
0.0LysXaa: 0.0 ± 0.0
Leu
10.702LeuAla: 10.702 ± 1.23
2.378LeuCys: 2.378 ± 1.102
7.134LeuAsp: 7.134 ± 1.732
1.189LeuGlu: 1.189 ± 0.883
1.189LeuPhe: 1.189 ± 0.883
8.323LeuGly: 8.323 ± 2.382
4.756LeuHis: 4.756 ± 2.203
1.189LeuIle: 1.189 ± 0.94
3.567LeuLys: 3.567 ± 0.41
4.756LeuLeu: 4.756 ± 2.203
0.0LeuMet: 0.0 ± 0.0
3.567LeuAsn: 3.567 ± 0.41
0.0LeuPro: 0.0 ± 0.0
4.756LeuGln: 4.756 ± 2.203
2.378LeuArg: 2.378 ± 1.102
3.567LeuSer: 3.567 ± 2.649
3.567LeuThr: 3.567 ± 0.41
3.567LeuVal: 3.567 ± 1.419
1.189LeuTrp: 1.189 ± 0.94
5.945LeuTyr: 5.945 ± 1.913
0.0LeuXaa: 0.0 ± 0.0
Met
2.378MetAla: 2.378 ± 1.102
1.189MetCys: 1.189 ± 1.118
0.0MetAsp: 0.0 ± 0.0
0.0MetGlu: 0.0 ± 0.0
2.378MetPhe: 2.378 ± 1.879
1.189MetGly: 1.189 ± 0.94
0.0MetHis: 0.0 ± 0.0
1.189MetIle: 1.189 ± 0.94
1.189MetLys: 1.189 ± 0.883
2.378MetLeu: 2.378 ± 1.879
0.0MetMet: 0.0 ± 0.0
1.189MetAsn: 1.189 ± 0.94
1.189MetPro: 1.189 ± 0.94
0.0MetGln: 0.0 ± 0.0
1.189MetArg: 1.189 ± 0.94
1.189MetSer: 1.189 ± 0.94
0.0MetThr: 0.0 ± 0.0
0.0MetVal: 0.0 ± 0.0
1.189MetTrp: 1.189 ± 0.94
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.378AsnAla: 2.378 ± 1.879
1.189AsnCys: 1.189 ± 0.883
2.378AsnAsp: 2.378 ± 1.879
2.378AsnGlu: 2.378 ± 1.102
1.189AsnPhe: 1.189 ± 0.94
3.567AsnGly: 3.567 ± 2.819
0.0AsnHis: 0.0 ± 0.0
4.756AsnIle: 4.756 ± 0.943
1.189AsnLys: 1.189 ± 0.94
5.945AsnLeu: 5.945 ± 1.371
1.189AsnMet: 1.189 ± 0.94
3.567AsnAsn: 3.567 ± 2.819
0.0AsnPro: 0.0 ± 0.0
1.189AsnGln: 1.189 ± 0.94
2.378AsnArg: 2.378 ± 1.879
2.378AsnSer: 2.378 ± 0.717
3.567AsnThr: 3.567 ± 1.419
2.378AsnVal: 2.378 ± 1.102
3.567AsnTrp: 3.567 ± 1.654
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.0ProCys: 0.0 ± 0.0
2.378ProAsp: 2.378 ± 1.102
5.945ProGlu: 5.945 ± 1.371
4.756ProPhe: 4.756 ± 2.203
0.0ProGly: 0.0 ± 0.0
1.189ProHis: 1.189 ± 0.883
2.378ProIle: 2.378 ± 1.102
1.189ProLys: 1.189 ± 0.883
1.189ProLeu: 1.189 ± 0.883
0.0ProMet: 0.0 ± 0.0
3.567ProAsn: 3.567 ± 0.41
0.0ProPro: 0.0 ± 0.0
1.189ProGln: 1.189 ± 0.94
4.756ProArg: 4.756 ± 0.737
5.945ProSer: 5.945 ± 1.574
1.189ProThr: 1.189 ± 0.94
4.756ProVal: 4.756 ± 0.737
3.567ProTrp: 3.567 ± 0.41
2.378ProTyr: 2.378 ± 1.102
0.0ProXaa: 0.0 ± 0.0
Gln
4.756GlnAla: 4.756 ± 0.737
2.378GlnCys: 2.378 ± 1.102
0.0GlnAsp: 0.0 ± 0.0
0.0GlnGlu: 0.0 ± 0.0
2.378GlnPhe: 2.378 ± 1.102
3.567GlnGly: 3.567 ± 1.654
0.0GlnHis: 0.0 ± 0.0
1.189GlnIle: 1.189 ± 0.94
2.378GlnLys: 2.378 ± 1.102
1.189GlnLeu: 1.189 ± 0.94
0.0GlnMet: 0.0 ± 0.0
2.378GlnAsn: 2.378 ± 1.879
0.0GlnPro: 0.0 ± 0.0
1.189GlnGln: 1.189 ± 0.94
1.189GlnArg: 1.189 ± 0.94
2.378GlnSer: 2.378 ± 1.879
1.189GlnThr: 1.189 ± 0.94
2.378GlnVal: 2.378 ± 0.717
2.378GlnTrp: 2.378 ± 0.717
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
5.945ArgAla: 5.945 ± 2.669
1.189ArgCys: 1.189 ± 0.94
4.756ArgAsp: 4.756 ± 0.943
2.378ArgGlu: 2.378 ± 1.102
1.189ArgPhe: 1.189 ± 0.94
7.134ArgGly: 7.134 ± 2.762
2.378ArgHis: 2.378 ± 1.102
2.378ArgIle: 2.378 ± 1.879
4.756ArgLys: 4.756 ± 0.943
3.567ArgLeu: 3.567 ± 1.306
0.0ArgMet: 0.0 ± 0.0
0.0ArgAsn: 0.0 ± 0.0
8.323ArgPro: 8.323 ± 3.733
2.378ArgGln: 2.378 ± 1.102
5.945ArgArg: 5.945 ± 1.837
4.756ArgSer: 4.756 ± 0.737
4.756ArgThr: 4.756 ± 0.943
1.189ArgVal: 1.189 ± 0.94
0.0ArgTrp: 0.0 ± 0.0
5.945ArgTyr: 5.945 ± 1.837
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
0.0SerCys: 0.0 ± 0.0
5.945SerAsp: 5.945 ± 1.574
0.0SerGlu: 0.0 ± 0.0
3.567SerPhe: 3.567 ± 0.41
10.702SerGly: 10.702 ± 1.107
1.189SerHis: 1.189 ± 0.883
3.567SerIle: 3.567 ± 1.654
3.567SerLys: 3.567 ± 2.819
5.945SerLeu: 5.945 ± 0.339
0.0SerMet: 0.0 ± 0.0
4.756SerAsn: 4.756 ± 0.737
2.378SerPro: 2.378 ± 0.717
4.756SerGln: 4.756 ± 0.943
7.134SerArg: 7.134 ± 1.732
7.134SerSer: 7.134 ± 2.762
5.945SerThr: 5.945 ± 1.837
2.378SerVal: 2.378 ± 0.717
0.0SerTrp: 0.0 ± 0.0
0.0SerTyr: 0.0 ± 0.0
0.0SerXaa: 0.0 ± 0.0
Thr
4.756ThrAla: 4.756 ± 2.298
1.189ThrCys: 1.189 ± 0.94
3.567ThrAsp: 3.567 ± 0.41
0.0ThrGlu: 0.0 ± 0.0
0.0ThrPhe: 0.0 ± 0.0
2.378ThrGly: 2.378 ± 1.879
0.0ThrHis: 0.0 ± 0.0
2.378ThrIle: 2.378 ± 1.102
1.189ThrLys: 1.189 ± 0.94
5.945ThrLeu: 5.945 ± 1.837
1.189ThrMet: 1.189 ± 0.94
1.189ThrAsn: 1.189 ± 0.94
7.134ThrPro: 7.134 ± 3.305
0.0ThrGln: 0.0 ± 0.0
9.512ThrArg: 9.512 ± 3.07
5.945ThrSer: 5.945 ± 0.339
1.189ThrThr: 1.189 ± 0.94
2.378ThrVal: 2.378 ± 0.717
4.756ThrTrp: 4.756 ± 0.737
3.567ThrTyr: 3.567 ± 0.41
0.0ThrXaa: 0.0 ± 0.0
Val
2.378ValAla: 2.378 ± 1.102
0.0ValCys: 0.0 ± 0.0
4.756ValAsp: 4.756 ± 0.943
2.378ValGlu: 2.378 ± 0.717
5.945ValPhe: 5.945 ± 2.669
5.945ValGly: 5.945 ± 1.371
0.0ValHis: 0.0 ± 0.0
1.189ValIle: 1.189 ± 0.883
1.189ValLys: 1.189 ± 0.883
2.378ValLeu: 2.378 ± 0.717
0.0ValMet: 0.0 ± 0.0
0.0ValAsn: 0.0 ± 0.0
2.378ValPro: 2.378 ± 0.717
0.0ValGln: 0.0 ± 0.0
2.378ValArg: 2.378 ± 1.102
7.134ValSer: 7.134 ± 2.762
2.378ValThr: 2.378 ± 1.102
5.945ValVal: 5.945 ± 1.837
1.189ValTrp: 1.189 ± 0.883
3.567ValTyr: 3.567 ± 2.819
0.0ValXaa: 0.0 ± 0.0
Trp
3.567TrpAla: 3.567 ± 1.654
0.0TrpCys: 0.0 ± 0.0
2.378TrpAsp: 2.378 ± 1.102
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
1.189TrpGly: 1.189 ± 0.883
4.756TrpHis: 4.756 ± 0.943
1.189TrpIle: 1.189 ± 0.94
2.378TrpLys: 2.378 ± 1.102
5.945TrpLeu: 5.945 ± 3.235
1.189TrpMet: 1.189 ± 0.94
0.0TrpAsn: 0.0 ± 0.0
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
4.756TrpArg: 4.756 ± 0.943
0.0TrpSer: 0.0 ± 0.0
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
4.756TyrAla: 4.756 ± 0.737
4.756TyrCys: 4.756 ± 2.203
4.756TyrAsp: 4.756 ± 0.943
2.378TyrGlu: 2.378 ± 1.102
3.567TyrPhe: 3.567 ± 1.419
3.567TyrGly: 3.567 ± 1.419
0.0TyrHis: 0.0 ± 0.0
0.0TyrIle: 0.0 ± 0.0
4.756TyrLys: 4.756 ± 2.298
0.0TyrLeu: 0.0 ± 0.0
1.189TyrMet: 1.189 ± 0.94
1.189TyrAsn: 1.189 ± 0.94
0.0TyrPro: 0.0 ± 0.0
1.189TyrGln: 1.189 ± 0.94
3.567TyrArg: 3.567 ± 0.41
5.945TyrSer: 5.945 ± 0.339
1.189TyrThr: 1.189 ± 0.94
1.189TyrVal: 1.189 ± 0.94
1.189TyrTrp: 1.189 ± 0.94
1.189TyrTyr: 1.189 ± 0.94
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (842 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski