Amino acid dipepetide frequency for Pseudobacter ginsenosidimutans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.649AlaAla: 7.649 ± 0.077	0.639AlaCys: 0.639 ± 0.017	4.222AlaAsp: 4.222 ± 0.046	4.231AlaGlu: 4.231 ± 0.045	3.542AlaPhe: 3.542 ± 0.037	6.619AlaGly: 6.619 ± 0.081	1.207AlaHis: 1.207 ± 0.024	5.356AlaIle: 5.356 ± 0.055	3.977AlaLys: 3.977 ± 0.05	6.739AlaLeu: 6.739 ± 0.06	1.878AlaMet: 1.878 ± 0.032	3.821AlaAsn: 3.821 ± 0.048	2.684AlaPro: 2.684 ± 0.037	2.919AlaGln: 2.919 ± 0.037	3.16AlaArg: 3.16 ± 0.037	5.121AlaSer: 5.121 ± 0.052	4.501AlaThr: 4.501 ± 0.053	5.052AlaVal: 5.052 ± 0.045	1.063AlaTrp: 1.063 ± 0.023	2.85AlaTyr: 2.85 ± 0.039	0.0AlaXaa: 0.0 ± 0.0
Cys	0.488CysAla: 0.488 ± 0.015	0.133CysCys: 0.133 ± 0.008	0.325CysAsp: 0.325 ± 0.012	0.325CysGlu: 0.325 ± 0.013	0.405CysPhe: 0.405 ± 0.013	0.573CysGly: 0.573 ± 0.015	0.135CysHis: 0.135 ± 0.008	0.573CysIle: 0.573 ± 0.018	0.455CysLys: 0.455 ± 0.016	0.718CysLeu: 0.718 ± 0.018	0.204CysMet: 0.204 ± 0.01	0.407CysAsn: 0.407 ± 0.014	0.285CysPro: 0.285 ± 0.015	0.184CysGln: 0.184 ± 0.008	0.374CysArg: 0.374 ± 0.013	0.553CysSer: 0.553 ± 0.017	0.421CysThr: 0.421 ± 0.013	0.391CysVal: 0.391 ± 0.013	0.109CysTrp: 0.109 ± 0.007	0.321CysTyr: 0.321 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	4.106AspAla: 4.106 ± 0.039	0.344AspCys: 0.344 ± 0.012	2.342AspAsp: 2.342 ± 0.034	3.093AspGlu: 3.093 ± 0.039	2.693AspPhe: 2.693 ± 0.036	4.049AspGly: 4.049 ± 0.05	1.087AspHis: 1.087 ± 0.023	3.656AspIle: 3.656 ± 0.039	3.193AspLys: 3.193 ± 0.039	4.976AspLeu: 4.976 ± 0.045	1.119AspMet: 1.119 ± 0.022	2.727AspAsn: 2.727 ± 0.041	2.536AspPro: 2.536 ± 0.034	1.938AspGln: 1.938 ± 0.03	2.157AspArg: 2.157 ± 0.032	2.936AspSer: 2.936 ± 0.043	2.409AspThr: 2.409 ± 0.038	3.071AspVal: 3.071 ± 0.037	0.755AspTrp: 0.755 ± 0.017	2.266AspTyr: 2.266 ± 0.036	0.0AspXaa: 0.0 ± 0.0
Glu	4.384GluAla: 4.384 ± 0.053	0.284GluCys: 0.284 ± 0.01	2.559GluAsp: 2.559 ± 0.036	3.515GluGlu: 3.515 ± 0.051	2.32GluPhe: 2.32 ± 0.029	3.532GluGly: 3.532 ± 0.037	0.92GluHis: 0.92 ± 0.022	3.733GluIle: 3.733 ± 0.043	4.694GluLys: 4.694 ± 0.053	5.698GluLeu: 5.698 ± 0.058	1.583GluMet: 1.583 ± 0.028	2.937GluAsn: 2.937 ± 0.037	1.78GluPro: 1.78 ± 0.031	2.532GluGln: 2.532 ± 0.034	2.577GluArg: 2.577 ± 0.035	2.672GluSer: 2.672 ± 0.037	2.692GluThr: 2.692 ± 0.033	3.503GluVal: 3.503 ± 0.043	0.712GluTrp: 0.712 ± 0.02	2.127GluTyr: 2.127 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	3.276PheAla: 3.276 ± 0.04	0.409PheCys: 0.409 ± 0.014	2.747PheAsp: 2.747 ± 0.031	2.485PheGlu: 2.485 ± 0.036	2.417PhePhe: 2.417 ± 0.036	3.164PheGly: 3.164 ± 0.041	0.837PheHis: 0.837 ± 0.021	3.133PheIle: 3.133 ± 0.04	2.546PheLys: 2.546 ± 0.035	4.454PheLeu: 4.454 ± 0.061	1.208PheMet: 1.208 ± 0.025	3.093PheAsn: 3.093 ± 0.033	1.965PhePro: 1.965 ± 0.03	1.496PheGln: 1.496 ± 0.025	2.507PheArg: 2.507 ± 0.034	3.807PheSer: 3.807 ± 0.043	3.315PheThr: 3.315 ± 0.039	2.718PheVal: 2.718 ± 0.035	0.606PheTrp: 0.606 ± 0.015	2.079PheTyr: 2.079 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	5.035GlyAla: 5.035 ± 0.064	0.632GlyCys: 0.632 ± 0.019	3.289GlyAsp: 3.289 ± 0.044	3.432GlyGlu: 3.432 ± 0.036	3.706GlyPhe: 3.706 ± 0.043	5.082GlyGly: 5.082 ± 0.082	1.104GlyHis: 1.104 ± 0.025	5.339GlyIle: 5.339 ± 0.049	5.452GlyLys: 5.452 ± 0.058	6.043GlyLeu: 6.043 ± 0.055	1.859GlyMet: 1.859 ± 0.03	4.407GlyAsn: 4.407 ± 0.061	1.692GlyPro: 1.692 ± 0.026	2.364GlyGln: 2.364 ± 0.03	3.01GlyArg: 3.01 ± 0.034	4.951GlySer: 4.951 ± 0.065	4.532GlyThr: 4.532 ± 0.064	4.439GlyVal: 4.439 ± 0.054	1.044GlyTrp: 1.044 ± 0.025	3.18GlyTyr: 3.18 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	1.195HisAla: 1.195 ± 0.021	0.163HisCys: 0.163 ± 0.008	0.745HisAsp: 0.745 ± 0.018	0.893HisGlu: 0.893 ± 0.023	1.179HisPhe: 1.179 ± 0.024	1.082HisGly: 1.082 ± 0.027	0.52HisHis: 0.52 ± 0.016	1.232HisIle: 1.232 ± 0.025	0.881HisLys: 0.881 ± 0.022	1.763HisLeu: 1.763 ± 0.034	0.387HisMet: 0.387 ± 0.013	0.876HisAsn: 0.876 ± 0.021	1.077HisPro: 1.077 ± 0.025	0.777HisGln: 0.777 ± 0.02	0.877HisArg: 0.877 ± 0.02	1.068HisSer: 1.068 ± 0.024	0.997HisThr: 0.997 ± 0.021	0.911HisVal: 0.911 ± 0.021	0.267HisTrp: 0.267 ± 0.012	0.829HisTyr: 0.829 ± 0.019	0.0HisXaa: 0.0 ± 0.0
Ile	5.538IleAla: 5.538 ± 0.061	0.618IleCys: 0.618 ± 0.019	3.768IleAsp: 3.768 ± 0.038	3.62IleGlu: 3.62 ± 0.05	2.913IlePhe: 2.913 ± 0.04	4.532IleGly: 4.532 ± 0.046	1.21IleHis: 1.21 ± 0.024	4.316IleIle: 4.316 ± 0.052	3.455IleLys: 3.455 ± 0.039	5.706IleLeu: 5.706 ± 0.061	1.304IleMet: 1.304 ± 0.026	3.773IleAsn: 3.773 ± 0.048	3.162IlePro: 3.162 ± 0.036	2.311IleGln: 2.311 ± 0.03	3.86IleArg: 3.86 ± 0.043	4.875IleSer: 4.875 ± 0.045	4.695IleThr: 4.695 ± 0.045	4.027IleVal: 4.027 ± 0.043	0.775IleTrp: 0.775 ± 0.016	2.334IleTyr: 2.334 ± 0.03	0.0IleXaa: 0.0 ± 0.0
Lys	4.654LysAla: 4.654 ± 0.048	0.281LysCys: 0.281 ± 0.011	3.796LysAsp: 3.796 ± 0.04	4.377LysGlu: 4.377 ± 0.045	2.281LysPhe: 2.281 ± 0.029	4.341LysGly: 4.341 ± 0.051	1.058LysHis: 1.058 ± 0.021	3.75LysIle: 3.75 ± 0.047	5.067LysLys: 5.067 ± 0.063	5.585LysLeu: 5.585 ± 0.054	1.883LysMet: 1.883 ± 0.031	3.442LysAsn: 3.442 ± 0.04	2.625LysPro: 2.625 ± 0.035	2.81LysGln: 2.81 ± 0.038	2.683LysArg: 2.683 ± 0.034	3.358LysSer: 3.358 ± 0.039	3.598LysThr: 3.598 ± 0.037	3.862LysVal: 3.862 ± 0.048	0.839LysTrp: 0.839 ± 0.021	2.476LysTyr: 2.476 ± 0.035	0.0LysXaa: 0.0 ± 0.0
Leu	6.71LeuAla: 6.71 ± 0.064	0.736LeuCys: 0.736 ± 0.018	4.493LeuAsp: 4.493 ± 0.049	4.818LeuGlu: 4.818 ± 0.05	4.711LeuPhe: 4.711 ± 0.054	5.422LeuGly: 5.422 ± 0.053	1.882LeuHis: 1.882 ± 0.034	5.729LeuIle: 5.729 ± 0.066	6.132LeuLys: 6.132 ± 0.054	10.186LeuLeu: 10.186 ± 0.093	2.309LeuMet: 2.309 ± 0.036	5.27LeuAsn: 5.27 ± 0.059	4.472LeuPro: 4.472 ± 0.047	4.467LeuGln: 4.467 ± 0.055	4.57LeuArg: 4.57 ± 0.044	7.02LeuSer: 7.02 ± 0.062	5.608LeuThr: 5.608 ± 0.047	5.572LeuVal: 5.572 ± 0.059	1.01LeuTrp: 1.01 ± 0.022	3.43LeuTyr: 3.43 ± 0.041	0.0LeuXaa: 0.0 ± 0.0
Met	1.954MetAla: 1.954 ± 0.03	0.119MetCys: 0.119 ± 0.007	1.299MetAsp: 1.299 ± 0.025	1.519MetGlu: 1.519 ± 0.031	0.899MetPhe: 0.899 ± 0.021	1.503MetGly: 1.503 ± 0.025	0.433MetHis: 0.433 ± 0.016	1.599MetIle: 1.599 ± 0.027	2.102MetLys: 2.102 ± 0.033	2.298MetLeu: 2.298 ± 0.031	0.737MetMet: 0.737 ± 0.019	1.403MetAsn: 1.403 ± 0.025	1.224MetPro: 1.224 ± 0.024	1.196MetGln: 1.196 ± 0.023	1.197MetArg: 1.197 ± 0.02	1.41MetSer: 1.41 ± 0.025	1.098MetThr: 1.098 ± 0.021	1.487MetVal: 1.487 ± 0.026	0.2MetTrp: 0.2 ± 0.01	0.752MetTyr: 0.752 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	4.337AsnAla: 4.337 ± 0.05	0.396AsnCys: 0.396 ± 0.017	2.748AsnAsp: 2.748 ± 0.035	2.895AsnGlu: 2.895 ± 0.034	2.523AsnPhe: 2.523 ± 0.036	4.698AsnGly: 4.698 ± 0.061	0.88AsnHis: 0.88 ± 0.02	4.032AsnIle: 4.032 ± 0.045	3.402AsnLys: 3.402 ± 0.042	4.727AsnLeu: 4.727 ± 0.055	1.288AsnMet: 1.288 ± 0.026	3.702AsnAsn: 3.702 ± 0.065	2.756AsnPro: 2.756 ± 0.036	2.07AsnGln: 2.07 ± 0.03	2.619AsnArg: 2.619 ± 0.034	3.376AsnSer: 3.376 ± 0.053	3.61AsnThr: 3.61 ± 0.056	3.111AsnVal: 3.111 ± 0.036	0.88AsnTrp: 0.88 ± 0.021	2.434AsnTyr: 2.434 ± 0.041	0.0AsnXaa: 0.0 ± 0.0
Pro	4.124ProAla: 4.124 ± 0.053	0.229ProCys: 0.229 ± 0.011	2.834ProAsp: 2.834 ± 0.039	2.758ProGlu: 2.758 ± 0.035	1.956ProPhe: 1.956 ± 0.029	3.646ProGly: 3.646 ± 0.043	0.644ProHis: 0.644 ± 0.017	2.012ProIle: 2.012 ± 0.029	1.825ProLys: 1.825 ± 0.034	3.655ProLeu: 3.655 ± 0.041	0.846ProMet: 0.846 ± 0.019	2.016ProAsn: 2.016 ± 0.032	1.368ProPro: 1.368 ± 0.029	1.458ProGln: 1.458 ± 0.022	1.379ProArg: 1.379 ± 0.022	2.391ProSer: 2.391 ± 0.036	1.929ProThr: 1.929 ± 0.031	3.963ProVal: 3.963 ± 0.043	0.501ProTrp: 0.501 ± 0.015	1.507ProTyr: 1.507 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	2.817GlnAla: 2.817 ± 0.037	0.229GlnCys: 0.229 ± 0.01	1.682GlnAsp: 1.682 ± 0.026	2.306GlnGlu: 2.306 ± 0.042	1.978GlnPhe: 1.978 ± 0.029	2.168GlnGly: 2.168 ± 0.032	0.855GlnHis: 0.855 ± 0.022	2.274GlnIle: 2.274 ± 0.031	2.388GlnLys: 2.388 ± 0.037	4.59GlnLeu: 4.59 ± 0.047	0.986GlnMet: 0.986 ± 0.02	1.868GlnAsn: 1.868 ± 0.031	1.879GlnPro: 1.879 ± 0.035	2.825GlnGln: 2.825 ± 0.05	1.808GlnArg: 1.808 ± 0.029	2.395GlnSer: 2.395 ± 0.03	2.212GlnThr: 2.212 ± 0.033	2.455GlnVal: 2.455 ± 0.036	0.554GlnTrp: 0.554 ± 0.017	1.751GlnTyr: 1.751 ± 0.027	0.0GlnXaa: 0.0 ± 0.0
Arg	2.793ArgAla: 2.793 ± 0.04	0.262ArgCys: 0.262 ± 0.011	2.171ArgAsp: 2.171 ± 0.027	2.752ArgGlu: 2.752 ± 0.044	2.457ArgPhe: 2.457 ± 0.032	2.495ArgGly: 2.495 ± 0.035	0.783ArgHis: 0.783 ± 0.019	3.51ArgIle: 3.51 ± 0.039	3.385ArgLys: 3.385 ± 0.042	4.321ArgLeu: 4.321 ± 0.045	1.301ArgMet: 1.301 ± 0.024	3.027ArgAsn: 3.027 ± 0.034	1.591ArgPro: 1.591 ± 0.027	1.89ArgGln: 1.89 ± 0.031	2.017ArgArg: 2.017 ± 0.035	2.831ArgSer: 2.831 ± 0.034	2.415ArgThr: 2.415 ± 0.033	2.689ArgVal: 2.689 ± 0.033	0.758ArgTrp: 0.758 ± 0.019	2.186ArgTyr: 2.186 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	4.815SerAla: 4.815 ± 0.047	0.569SerCys: 0.569 ± 0.019	2.992SerAsp: 2.992 ± 0.036	2.831SerGlu: 2.831 ± 0.034	3.781SerPhe: 3.781 ± 0.043	5.389SerGly: 5.389 ± 0.063	1.112SerHis: 1.112 ± 0.023	4.772SerIle: 4.772 ± 0.044	3.436SerLys: 3.436 ± 0.038	6.301SerLeu: 6.301 ± 0.059	1.452SerMet: 1.452 ± 0.028	3.562SerAsn: 3.562 ± 0.044	2.559SerPro: 2.559 ± 0.033	2.088SerGln: 2.088 ± 0.03	2.977SerArg: 2.977 ± 0.038	4.554SerSer: 4.554 ± 0.058	3.785SerThr: 3.785 ± 0.045	4.359SerVal: 4.359 ± 0.042	0.954SerTrp: 0.954 ± 0.022	2.68SerTyr: 2.68 ± 0.038	0.0SerXaa: 0.0 ± 0.0
Thr	5.044ThrAla: 5.044 ± 0.054	0.348ThrCys: 0.348 ± 0.015	3.404ThrAsp: 3.404 ± 0.042	2.91ThrGlu: 2.91 ± 0.035	2.491ThrPhe: 2.491 ± 0.036	5.466ThrGly: 5.466 ± 0.065	0.931ThrHis: 0.931 ± 0.021	4.429ThrIle: 4.429 ± 0.054	2.769ThrLys: 2.769 ± 0.035	5.324ThrLeu: 5.324 ± 0.053	1.173ThrMet: 1.173 ± 0.025	3.125ThrAsn: 3.125 ± 0.045	2.686ThrPro: 2.686 ± 0.034	1.855ThrGln: 1.855 ± 0.025	2.383ThrArg: 2.383 ± 0.03	3.564ThrSer: 3.564 ± 0.046	3.799ThrThr: 3.799 ± 0.053	4.263ThrVal: 4.263 ± 0.049	0.848ThrTrp: 0.848 ± 0.019	2.245ThrTyr: 2.245 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	4.568ValAla: 4.568 ± 0.054	0.525ValCys: 0.525 ± 0.015	3.02ValAsp: 3.02 ± 0.041	3.21ValGlu: 3.21 ± 0.038	3.12ValPhe: 3.12 ± 0.034	3.296ValGly: 3.296 ± 0.044	1.079ValHis: 1.079 ± 0.022	4.338ValIle: 4.338 ± 0.045	4.246ValLys: 4.246 ± 0.043	6.155ValLeu: 6.155 ± 0.058	1.669ValMet: 1.669 ± 0.03	3.793ValAsn: 3.793 ± 0.051	2.557ValPro: 2.557 ± 0.032	2.488ValGln: 2.488 ± 0.034	2.803ValArg: 2.803 ± 0.038	4.445ValSer: 4.445 ± 0.05	4.072ValThr: 4.072 ± 0.048	4.166ValVal: 4.166 ± 0.046	0.771ValTrp: 0.771 ± 0.019	2.587ValTyr: 2.587 ± 0.031	0.0ValXaa: 0.0 ± 0.0
Trp	0.835TrpAla: 0.835 ± 0.018	0.126TrpCys: 0.126 ± 0.007	0.703TrpAsp: 0.703 ± 0.02	0.753TrpGlu: 0.753 ± 0.022	0.694TrpPhe: 0.694 ± 0.017	0.814TrpGly: 0.814 ± 0.02	0.256TrpHis: 0.256 ± 0.011	0.828TrpIle: 0.828 ± 0.019	0.987TrpLys: 0.987 ± 0.021	1.458TrpLeu: 1.458 ± 0.024	0.449TrpMet: 0.449 ± 0.015	0.806TrpAsn: 0.806 ± 0.02	0.407TrpPro: 0.407 ± 0.012	0.698TrpGln: 0.698 ± 0.019	0.603TrpArg: 0.603 ± 0.017	0.783TrpSer: 0.783 ± 0.019	0.701TrpThr: 0.701 ± 0.021	0.738TrpVal: 0.738 ± 0.02	0.258TrpTrp: 0.258 ± 0.011	0.568TrpTyr: 0.568 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.91TyrAla: 2.91 ± 0.039	0.338TyrCys: 0.338 ± 0.011	2.313TyrAsp: 2.313 ± 0.032	2.032TyrGlu: 2.032 ± 0.029	2.197TyrPhe: 2.197 ± 0.032	2.719TyrGly: 2.719 ± 0.041	0.789TyrHis: 0.789 ± 0.017	2.179TyrIle: 2.179 ± 0.033	2.373TyrLys: 2.373 ± 0.033	3.85TyrLeu: 3.85 ± 0.043	0.796TyrMet: 0.796 ± 0.018	2.427TyrAsn: 2.427 ± 0.04	1.737TyrPro: 1.737 ± 0.027	1.654TyrGln: 1.654 ± 0.027	2.072TyrArg: 2.072 ± 0.03	2.855TyrSer: 2.855 ± 0.039	2.67TyrThr: 2.67 ± 0.04	2.13TyrVal: 2.13 ± 0.029	0.56TyrTrp: 0.56 ± 0.014	1.895TyrTyr: 1.895 ± 0.032	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 6020 proteins (2375140 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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