Amino acid dipepetide frequency for Soybean yellow mottle mosaic virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.043AlaAla: 4.043 ± 2.207
0.674AlaCys: 0.674 ± 0.395
2.022AlaAsp: 2.022 ± 1.072
2.022AlaGlu: 2.022 ± 1.185
1.348AlaPhe: 1.348 ± 0.79
3.369AlaGly: 3.369 ± 2.301
2.022AlaHis: 2.022 ± 2.07
4.717AlaIle: 4.717 ± 2.007
3.369AlaLys: 3.369 ± 0.466
8.086AlaLeu: 8.086 ± 1.013
0.0AlaMet: 0.0 ± 0.0
4.043AlaAsn: 4.043 ± 1.684
2.695AlaPro: 2.695 ± 1.026
2.695AlaGln: 2.695 ± 0.96
5.391AlaArg: 5.391 ± 1.214
2.695AlaSer: 2.695 ± 1.164
6.065AlaThr: 6.065 ± 3.177
8.086AlaVal: 8.086 ± 2.076
1.348AlaTrp: 1.348 ± 0.79
2.695AlaTyr: 2.695 ± 1.682
0.0AlaXaa: 0.0 ± 0.0
Cys
2.022CysAla: 2.022 ± 0.659
0.674CysCys: 0.674 ± 0.395
0.0CysAsp: 0.0 ± 0.0
1.348CysGlu: 1.348 ± 0.508
0.0CysPhe: 0.0 ± 0.0
1.348CysGly: 1.348 ± 0.79
0.674CysHis: 0.674 ± 0.395
1.348CysIle: 1.348 ± 0.79
0.0CysLys: 0.0 ± 0.0
2.695CysLeu: 2.695 ± 1.382
0.0CysMet: 0.0 ± 0.0
1.348CysAsn: 1.348 ± 0.691
0.674CysPro: 0.674 ± 0.861
1.348CysGln: 1.348 ± 0.691
1.348CysArg: 1.348 ± 0.79
1.348CysSer: 1.348 ± 0.691
0.674CysThr: 0.674 ± 0.861
1.348CysVal: 1.348 ± 0.79
0.0CysTrp: 0.0 ± 0.0
1.348CysTyr: 1.348 ± 0.727
0.0CysXaa: 0.0 ± 0.0
Asp
6.065AspAla: 6.065 ± 1.857
0.674AspCys: 0.674 ± 0.395
0.674AspAsp: 0.674 ± 0.395
1.348AspGlu: 1.348 ± 0.691
2.022AspPhe: 2.022 ± 0.975
0.674AspGly: 0.674 ± 0.395
1.348AspHis: 1.348 ± 1.011
0.674AspIle: 0.674 ± 0.395
2.695AspLys: 2.695 ± 2.178
1.348AspLeu: 1.348 ± 0.508
2.695AspMet: 2.695 ± 0.96
4.717AspAsn: 4.717 ± 1.594
6.065AspPro: 6.065 ± 1.072
1.348AspGln: 1.348 ± 0.79
1.348AspArg: 1.348 ± 0.975
6.739AspSer: 6.739 ± 1.58
1.348AspThr: 1.348 ± 0.508
2.695AspVal: 2.695 ± 0.96
0.0AspTrp: 0.0 ± 0.0
0.0AspTyr: 0.0 ± 0.0
0.0AspXaa: 0.0 ± 0.0
Glu
2.022GluAla: 2.022 ± 1.185
1.348GluCys: 1.348 ± 0.691
0.674GluAsp: 0.674 ± 0.395
2.022GluGlu: 2.022 ± 1.511
1.348GluPhe: 1.348 ± 0.79
2.695GluGly: 2.695 ± 0.96
2.695GluHis: 2.695 ± 1.58
0.674GluIle: 0.674 ± 0.628
4.043GluLys: 4.043 ± 0.772
3.369GluLeu: 3.369 ± 1.161
1.348GluMet: 1.348 ± 0.688
0.674GluAsn: 0.674 ± 1.03
2.022GluPro: 2.022 ± 1.185
0.0GluGln: 0.0 ± 0.0
2.695GluArg: 2.695 ± 1.58
2.695GluSer: 2.695 ± 1.419
0.0GluThr: 0.0 ± 0.0
4.043GluVal: 4.043 ± 0.976
0.0GluTrp: 0.0 ± 0.0
0.674GluTyr: 0.674 ± 0.861
0.0GluXaa: 0.0 ± 0.0
Phe
1.348PheAla: 1.348 ± 0.508
1.348PheCys: 1.348 ± 0.79
2.695PheAsp: 2.695 ± 1.014
2.022PheGlu: 2.022 ± 1.185
0.0PhePhe: 0.0 ± 0.0
4.043PheGly: 4.043 ± 1.318
0.0PheHis: 0.0 ± 0.0
0.674PheIle: 0.674 ± 0.395
0.674PheLys: 0.674 ± 0.395
1.348PheLeu: 1.348 ± 0.79
0.0PheMet: 0.0 ± 0.0
4.043PheAsn: 4.043 ± 1.166
0.674PhePro: 0.674 ± 0.395
0.674PheGln: 0.674 ± 0.395
2.022PheArg: 2.022 ± 0.659
5.391PheSer: 5.391 ± 1.021
1.348PheThr: 1.348 ± 0.79
2.022PheVal: 2.022 ± 1.246
0.0PheTrp: 0.0 ± 0.0
2.695PheTyr: 2.695 ± 1.138
0.0PheXaa: 0.0 ± 0.0
Gly
3.369GlyAla: 3.369 ± 3.139
3.369GlyCys: 3.369 ± 1.247
5.391GlyAsp: 5.391 ± 2.745
1.348GlyGlu: 1.348 ± 0.975
4.043GlyPhe: 4.043 ± 2.37
2.022GlyGly: 2.022 ± 2.002
1.348GlyHis: 1.348 ± 0.691
2.022GlyIle: 2.022 ± 1.185
5.391GlyLys: 5.391 ± 1.517
3.369GlyLeu: 3.369 ± 1.312
2.022GlyMet: 2.022 ± 0.725
2.695GlyAsn: 2.695 ± 1.58
4.717GlyPro: 4.717 ± 1.9
2.022GlyGln: 2.022 ± 0.659
3.369GlyArg: 3.369 ± 1.165
2.695GlySer: 2.695 ± 1.048
5.391GlyThr: 5.391 ± 1.94
6.065GlyVal: 6.065 ± 0.9
0.674GlyTrp: 0.674 ± 0.395
3.369GlyTyr: 3.369 ± 1.312
0.0GlyXaa: 0.0 ± 0.0
His
1.348HisAla: 1.348 ± 1.011
0.0HisCys: 0.0 ± 0.0
1.348HisAsp: 1.348 ± 0.508
2.022HisGlu: 2.022 ± 1.985
2.695HisPhe: 2.695 ± 1.58
2.022HisGly: 2.022 ± 1.139
1.348HisHis: 1.348 ± 1.011
0.674HisIle: 0.674 ± 0.784
0.674HisLys: 0.674 ± 0.395
2.695HisLeu: 2.695 ± 1.138
0.674HisMet: 0.674 ± 0.861
0.674HisAsn: 0.674 ± 0.395
0.674HisPro: 0.674 ± 0.395
0.674HisGln: 0.674 ± 0.395
0.674HisArg: 0.674 ± 0.395
4.043HisSer: 4.043 ± 1.462
2.695HisThr: 2.695 ± 0.966
2.022HisVal: 2.022 ± 1.185
0.0HisTrp: 0.0 ± 0.0
0.674HisTyr: 0.674 ± 0.395
0.0HisXaa: 0.0 ± 0.0
Ile
4.043IleAla: 4.043 ± 1.865
0.674IleCys: 0.674 ± 0.861
2.695IleAsp: 2.695 ± 1.58
1.348IleGlu: 1.348 ± 0.79
2.022IlePhe: 2.022 ± 1.459
3.369IleGly: 3.369 ± 1.247
0.0IleHis: 0.0 ± 0.0
1.348IleIle: 1.348 ± 0.508
2.695IleLys: 2.695 ± 1.016
5.391IleLeu: 5.391 ± 4.522
3.369IleMet: 3.369 ± 1.1
2.695IleAsn: 2.695 ± 0.966
2.022IlePro: 2.022 ± 0.869
3.369IleGln: 3.369 ± 0.925
1.348IleArg: 1.348 ± 0.727
2.695IleSer: 2.695 ± 1.026
5.391IleThr: 5.391 ± 1.389
3.369IleVal: 3.369 ± 1.458
0.0IleTrp: 0.0 ± 0.0
1.348IleTyr: 1.348 ± 0.508
0.0IleXaa: 0.0 ± 0.0
Lys
1.348LysAla: 1.348 ± 1.011
0.674LysCys: 0.674 ± 0.861
1.348LysAsp: 1.348 ± 0.79
1.348LysGlu: 1.348 ± 1.256
2.695LysPhe: 2.695 ± 1.58
3.369LysGly: 3.369 ± 1.668
2.022LysHis: 2.022 ± 0.869
2.695LysIle: 2.695 ± 0.695
1.348LysLys: 1.348 ± 0.508
6.065LysLeu: 6.065 ± 1.899
0.674LysMet: 0.674 ± 0.9
1.348LysAsn: 1.348 ± 0.508
6.739LysPro: 6.739 ± 2.216
2.022LysGln: 2.022 ± 1.429
2.695LysArg: 2.695 ± 0.96
3.369LysSer: 3.369 ± 0.925
1.348LysThr: 1.348 ± 0.975
1.348LysVal: 1.348 ± 0.79
0.674LysTrp: 0.674 ± 0.395
0.0LysTyr: 0.0 ± 0.0
0.0LysXaa: 0.0 ± 0.0
Leu
10.108LeuAla: 10.108 ± 2.335
0.674LeuCys: 0.674 ± 0.861
4.043LeuAsp: 4.043 ± 1.328
2.695LeuGlu: 2.695 ± 0.941
0.674LeuPhe: 0.674 ± 0.861
5.391LeuGly: 5.391 ± 1.021
2.695LeuHis: 2.695 ± 1.58
8.76LeuIle: 8.76 ± 2.684
3.369LeuLys: 3.369 ± 1.109
9.434LeuLeu: 9.434 ± 2.501
4.043LeuMet: 4.043 ± 0.581
5.391LeuAsn: 5.391 ± 1.021
4.043LeuPro: 4.043 ± 4.075
6.065LeuGln: 6.065 ± 1.627
6.065LeuArg: 6.065 ± 1.24
10.108LeuSer: 10.108 ± 2.6
5.391LeuThr: 5.391 ± 2.838
4.717LeuVal: 4.717 ± 0.652
2.022LeuTrp: 2.022 ± 0.74
2.695LeuTyr: 2.695 ± 1.58
0.0LeuXaa: 0.0 ± 0.0
Met
1.348MetAla: 1.348 ± 0.508
0.674MetCys: 0.674 ± 0.861
1.348MetAsp: 1.348 ± 1.418
2.022MetGlu: 2.022 ± 1.511
1.348MetPhe: 1.348 ± 0.975
2.695MetGly: 2.695 ± 1.58
0.674MetHis: 0.674 ± 0.395
2.022MetIle: 2.022 ± 1.511
0.674MetLys: 0.674 ± 0.395
2.695MetLeu: 2.695 ± 1.419
0.674MetMet: 0.674 ± 0.395
2.022MetAsn: 2.022 ± 0.659
1.348MetPro: 1.348 ± 0.727
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
4.043MetSer: 4.043 ± 0.772
1.348MetThr: 1.348 ± 0.79
1.348MetVal: 1.348 ± 0.508
0.0MetTrp: 0.0 ± 0.0
0.674MetTyr: 0.674 ± 0.628
0.0MetXaa: 0.0 ± 0.0
Asn
1.348AsnAla: 1.348 ± 0.79
2.695AsnCys: 2.695 ± 0.96
1.348AsnAsp: 1.348 ± 0.79
1.348AsnGlu: 1.348 ± 0.79
1.348AsnPhe: 1.348 ± 1.011
6.065AsnGly: 6.065 ± 2.09
1.348AsnHis: 1.348 ± 0.727
3.369AsnIle: 3.369 ± 2.097
2.695AsnLys: 2.695 ± 0.966
6.065AsnLeu: 6.065 ± 3.555
0.674AsnMet: 0.674 ± 0.628
1.348AsnAsn: 1.348 ± 0.79
3.369AsnPro: 3.369 ± 1.717
2.022AsnGln: 2.022 ± 0.659
3.369AsnArg: 3.369 ± 1.36
5.391AsnSer: 5.391 ± 1.792
1.348AsnThr: 1.348 ± 0.79
4.043AsnVal: 4.043 ± 2.144
2.022AsnTrp: 2.022 ± 0.659
0.674AsnTyr: 0.674 ± 0.628
0.0AsnXaa: 0.0 ± 0.0
Pro
3.369ProAla: 3.369 ± 1.556
0.0ProCys: 0.0 ± 0.0
3.369ProAsp: 3.369 ± 1.109
2.695ProGlu: 2.695 ± 1.373
1.348ProPhe: 1.348 ± 0.508
3.369ProGly: 3.369 ± 0.925
0.674ProHis: 0.674 ± 0.628
0.674ProIle: 0.674 ± 0.395
3.369ProLys: 3.369 ± 1.884
10.108ProLeu: 10.108 ± 3.742
1.348ProMet: 1.348 ± 1.723
3.369ProAsn: 3.369 ± 0.75
5.391ProPro: 5.391 ± 0.754
2.022ProGln: 2.022 ± 1.429
7.412ProArg: 7.412 ± 1.513
5.391ProSer: 5.391 ± 5.362
2.022ProThr: 2.022 ± 0.659
6.739ProVal: 6.739 ± 1.616
0.0ProTrp: 0.0 ± 0.0
0.674ProTyr: 0.674 ± 0.784
0.0ProXaa: 0.0 ± 0.0
Gln
1.348GlnAla: 1.348 ± 0.508
0.674GlnCys: 0.674 ± 0.395
1.348GlnAsp: 1.348 ± 0.79
1.348GlnGlu: 1.348 ± 0.79
0.674GlnPhe: 0.674 ± 0.395
2.022GlnGly: 2.022 ± 1.429
4.717GlnHis: 4.717 ± 1.805
2.022GlnIle: 2.022 ± 1.139
0.0GlnLys: 0.0 ± 0.0
2.695GlnLeu: 2.695 ± 1.682
0.0GlnMet: 0.0 ± 0.0
0.674GlnAsn: 0.674 ± 0.628
4.717GlnPro: 4.717 ± 0.657
2.695GlnGln: 2.695 ± 0.386
2.695GlnArg: 2.695 ± 1.692
1.348GlnSer: 1.348 ± 0.727
2.695GlnThr: 2.695 ± 1.888
4.043GlnVal: 4.043 ± 1.432
0.674GlnTrp: 0.674 ± 0.395
0.674GlnTyr: 0.674 ± 0.395
0.674GlnXaa: 0.674 ± 0.395
Arg
2.695ArgAla: 2.695 ± 0.96
0.674ArgCys: 0.674 ± 0.628
3.369ArgAsp: 3.369 ± 1.591
1.348ArgGlu: 1.348 ± 0.79
3.369ArgPhe: 3.369 ± 1.109
5.391ArgGly: 5.391 ± 2.745
1.348ArgHis: 1.348 ± 0.727
2.022ArgIle: 2.022 ± 0.659
5.391ArgLys: 5.391 ± 1.107
7.412ArgLeu: 7.412 ± 0.845
1.348ArgMet: 1.348 ± 0.691
2.695ArgAsn: 2.695 ± 1.58
2.022ArgPro: 2.022 ± 0.627
2.022ArgGln: 2.022 ± 0.975
6.739ArgArg: 6.739 ± 0.931
7.412ArgSer: 7.412 ± 4.518
4.717ArgThr: 4.717 ± 0.964
5.391ArgVal: 5.391 ± 1.392
0.0ArgTrp: 0.0 ± 0.0
4.717ArgTyr: 4.717 ± 1.135
0.0ArgXaa: 0.0 ± 0.0
Ser
5.391SerAla: 5.391 ± 1.181
0.674SerCys: 0.674 ± 0.395
4.043SerAsp: 4.043 ± 2.207
2.695SerGlu: 2.695 ± 0.941
2.022SerPhe: 2.022 ± 0.725
6.065SerGly: 6.065 ± 1.072
0.674SerHis: 0.674 ± 0.395
4.717SerIle: 4.717 ± 2.038
4.043SerLys: 4.043 ± 1.488
7.412SerLeu: 7.412 ± 3.399
2.022SerMet: 2.022 ± 0.666
5.391SerAsn: 5.391 ± 2.697
7.412SerPro: 7.412 ± 6.163
2.695SerGln: 2.695 ± 1.787
5.391SerArg: 5.391 ± 3.3
7.412SerSer: 7.412 ± 3.377
12.129SerThr: 12.129 ± 5.127
3.369SerVal: 3.369 ± 1.312
2.022SerTrp: 2.022 ± 1.511
2.022SerTyr: 2.022 ± 0.627
0.0SerXaa: 0.0 ± 0.0
Thr
6.739ThrAla: 6.739 ± 2.396
1.348ThrCys: 1.348 ± 0.691
2.695ThrAsp: 2.695 ± 1.048
2.695ThrGlu: 2.695 ± 1.682
3.369ThrPhe: 3.369 ± 1.556
3.369ThrGly: 3.369 ± 0.999
1.348ThrHis: 1.348 ± 0.727
2.695ThrIle: 2.695 ± 1.048
0.674ThrLys: 0.674 ± 0.395
8.086ThrLeu: 8.086 ± 4.669
2.022ThrMet: 2.022 ± 0.659
3.369ThrAsn: 3.369 ± 1.661
6.065ThrPro: 6.065 ± 1.014
2.022ThrGln: 2.022 ± 1.246
4.043ThrArg: 4.043 ± 0.976
4.043ThrSer: 4.043 ± 2.535
4.717ThrThr: 4.717 ± 3.717
4.043ThrVal: 4.043 ± 1.918
1.348ThrTrp: 1.348 ± 0.691
1.348ThrTyr: 1.348 ± 0.508
0.0ThrXaa: 0.0 ± 0.0
Val
6.739ValAla: 6.739 ± 2.293
1.348ValCys: 1.348 ± 0.79
4.043ValAsp: 4.043 ± 1.166
2.695ValGlu: 2.695 ± 1.58
1.348ValPhe: 1.348 ± 0.508
4.043ValGly: 4.043 ± 1.135
1.348ValHis: 1.348 ± 0.79
5.391ValIle: 5.391 ± 1.63
0.674ValLys: 0.674 ± 0.395
3.369ValLeu: 3.369 ± 1.556
2.695ValMet: 2.695 ± 1.382
3.369ValAsn: 3.369 ± 1.074
2.695ValPro: 2.695 ± 1.016
2.695ValGln: 2.695 ± 1.682
8.76ValArg: 8.76 ± 1.17
8.76ValSer: 8.76 ± 2.822
5.391ValThr: 5.391 ± 1.826
4.043ValVal: 4.043 ± 1.684
0.0ValTrp: 0.0 ± 0.0
2.695ValTyr: 2.695 ± 0.695
0.0ValXaa: 0.0 ± 0.0
Trp
0.674TrpAla: 0.674 ± 0.395
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.0TrpGlu: 0.0 ± 0.0
0.0TrpPhe: 0.0 ± 0.0
0.674TrpGly: 0.674 ± 0.628
0.674TrpHis: 0.674 ± 0.784
0.674TrpIle: 0.674 ± 0.395
1.348TrpLys: 1.348 ± 0.79
3.369TrpLeu: 3.369 ± 2.186
0.0TrpMet: 0.0 ± 0.0
1.348TrpAsn: 1.348 ± 0.79
0.0TrpPro: 0.0 ± 0.0
0.674TrpGln: 0.674 ± 0.395
0.674TrpArg: 0.674 ± 0.861
0.674TrpSer: 0.674 ± 0.395
0.0TrpThr: 0.0 ± 0.0
0.674TrpVal: 0.674 ± 0.628
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.022TyrAla: 2.022 ± 1.072
1.348TyrCys: 1.348 ± 0.727
2.022TyrAsp: 2.022 ± 0.659
0.674TyrGlu: 0.674 ± 0.395
1.348TyrPhe: 1.348 ± 0.79
2.022TyrGly: 2.022 ± 0.627
0.674TyrHis: 0.674 ± 0.395
2.022TyrIle: 2.022 ± 1.638
0.674TyrLys: 0.674 ± 0.395
3.369TyrLeu: 3.369 ± 1.312
0.674TyrMet: 0.674 ± 0.395
0.674TyrAsn: 0.674 ± 0.395
0.0TyrPro: 0.0 ± 0.0
0.674TyrGln: 0.674 ± 0.395
4.043TyrArg: 4.043 ± 0.772
1.348TyrSer: 1.348 ± 0.727
2.022TyrThr: 2.022 ± 1.072
2.695TyrVal: 2.695 ± 1.016
0.674TyrTrp: 0.674 ± 0.861
0.674TyrTyr: 0.674 ± 0.395
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.674XaaGly: 0.674 ± 0.395
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1485 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski