Amino acid dipepetide frequency for Changjiang picorna-like virus 7

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.612AlaAla: 7.612 ± 2.35
0.401AlaCys: 0.401 ± 0.435
2.804AlaAsp: 2.804 ± 1.073
5.208AlaGlu: 5.208 ± 0.258
4.006AlaPhe: 4.006 ± 1.064
4.808AlaGly: 4.808 ± 1.933
0.401AlaHis: 0.401 ± 0.435
3.205AlaIle: 3.205 ± 1.118
4.006AlaLys: 4.006 ± 0.906
6.01AlaLeu: 6.01 ± 0.611
2.804AlaMet: 2.804 ± 0.896
3.205AlaAsn: 3.205 ± 0.195
4.808AlaPro: 4.808 ± 0.62
2.404AlaGln: 2.404 ± 0.675
4.407AlaArg: 4.407 ± 0.186
7.612AlaSer: 7.612 ± 0.276
6.811AlaThr: 6.811 ± 0.824
8.413AlaVal: 8.413 ± 1.249
0.401AlaTrp: 0.401 ± 0.222
2.003AlaTyr: 2.003 ± 0.204
0.0AlaXaa: 0.0 ± 0.0
Cys
0.801CysAla: 0.801 ± 0.869
0.401CysCys: 0.401 ± 0.222
0.401CysAsp: 0.401 ± 0.435
0.401CysGlu: 0.401 ± 0.222
0.801CysPhe: 0.801 ± 0.444
0.801CysGly: 0.801 ± 0.213
0.0CysHis: 0.0 ± 0.0
2.003CysIle: 2.003 ± 0.204
0.0CysLys: 0.0 ± 0.0
1.603CysLeu: 1.603 ± 0.887
0.401CysMet: 0.401 ± 0.222
0.401CysAsn: 0.401 ± 0.435
1.202CysPro: 1.202 ± 0.647
0.0CysGln: 0.0 ± 0.0
1.202CysArg: 1.202 ± 0.666
1.603CysSer: 1.603 ± 0.426
1.603CysThr: 1.603 ± 0.426
0.0CysVal: 0.0 ± 0.0
0.401CysTrp: 0.401 ± 0.222
1.603CysTyr: 1.603 ± 0.231
0.0CysXaa: 0.0 ± 0.0
Asp
3.606AspAla: 3.606 ± 0.684
1.202AspCys: 1.202 ± 0.666
4.808AspAsp: 4.808 ± 1.349
2.804AspGlu: 2.804 ± 0.416
2.804AspPhe: 2.804 ± 0.24
3.606AspGly: 3.606 ± 0.684
0.801AspHis: 0.801 ± 0.213
4.006AspIle: 4.006 ± 0.249
2.003AspLys: 2.003 ± 0.453
5.208AspLeu: 5.208 ± 0.398
3.606AspMet: 3.606 ± 1.997
2.404AspAsn: 2.404 ± 0.638
0.401AspPro: 0.401 ± 0.435
0.801AspGln: 0.801 ± 0.444
2.804AspArg: 2.804 ± 0.416
2.804AspSer: 2.804 ± 1.553
0.801AspThr: 0.801 ± 0.213
2.804AspVal: 2.804 ± 0.416
0.401AspTrp: 0.401 ± 0.435
2.804AspTyr: 2.804 ± 0.416
0.0AspXaa: 0.0 ± 0.0
Glu
5.609GluAla: 5.609 ± 0.176
0.801GluCys: 0.801 ± 0.444
3.205GluAsp: 3.205 ± 0.851
5.208GluGlu: 5.208 ± 0.915
2.404GluPhe: 2.404 ± 1.331
3.205GluGly: 3.205 ± 0.195
0.801GluHis: 0.801 ± 0.444
2.804GluIle: 2.804 ± 0.896
3.606GluLys: 3.606 ± 0.684
4.808GluLeu: 4.808 ± 1.349
2.404GluMet: 2.404 ± 0.675
3.205GluAsn: 3.205 ± 1.118
1.603GluPro: 1.603 ± 0.231
2.804GluGln: 2.804 ± 0.896
4.006GluArg: 4.006 ± 2.219
2.404GluSer: 2.404 ± 0.018
2.003GluThr: 2.003 ± 0.453
3.606GluVal: 3.606 ± 0.027
1.603GluTrp: 1.603 ± 0.231
2.404GluTyr: 2.404 ± 1.295
0.0GluXaa: 0.0 ± 0.0
Phe
4.808PheAla: 4.808 ± 0.036
0.0PheCys: 0.0 ± 0.0
3.606PheAsp: 3.606 ± 1.34
2.003PheGlu: 2.003 ± 0.204
1.202PhePhe: 1.202 ± 0.666
5.609PheGly: 5.609 ± 0.176
1.603PheHis: 1.603 ± 0.231
2.003PheIle: 2.003 ± 0.204
2.003PheLys: 2.003 ± 0.86
4.407PheLeu: 4.407 ± 1.784
2.003PheMet: 2.003 ± 0.369
3.606PheAsn: 3.606 ± 0.027
2.404PhePro: 2.404 ± 0.018
2.804PheGln: 2.804 ± 0.416
2.003PheArg: 2.003 ± 1.517
4.006PheSer: 4.006 ± 0.407
2.404PheThr: 2.404 ± 0.018
2.804PheVal: 2.804 ± 0.24
0.401PheTrp: 0.401 ± 0.435
0.801PheTyr: 0.801 ± 0.869
0.0PheXaa: 0.0 ± 0.0
Gly
5.609GlyAla: 5.609 ± 2.146
2.003GlyCys: 2.003 ± 1.517
5.609GlyAsp: 5.609 ± 1.793
2.804GlyGlu: 2.804 ± 1.073
4.006GlyPhe: 4.006 ± 0.407
3.606GlyGly: 3.606 ± 1.286
1.603GlyHis: 1.603 ± 0.426
2.804GlyIle: 2.804 ± 0.416
3.205GlyLys: 3.205 ± 1.775
6.41GlyLeu: 6.41 ± 1.58
2.404GlyMet: 2.404 ± 1.331
4.006GlyAsn: 4.006 ± 1.72
1.603GlyPro: 1.603 ± 0.426
2.804GlyGln: 2.804 ± 0.24
4.006GlyArg: 4.006 ± 0.407
4.006GlySer: 4.006 ± 1.72
5.208GlyThr: 5.208 ± 2.368
5.609GlyVal: 5.609 ± 0.833
1.202GlyTrp: 1.202 ± 0.666
2.404GlyTyr: 2.404 ± 0.018
0.0GlyXaa: 0.0 ± 0.0
His
1.202HisAla: 1.202 ± 0.009
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
2.404HisGlu: 2.404 ± 1.331
0.801HisPhe: 0.801 ± 0.213
0.801HisGly: 0.801 ± 0.213
0.401HisHis: 0.401 ± 0.222
1.603HisIle: 1.603 ± 0.887
0.0HisLys: 0.0 ± 0.0
1.202HisLeu: 1.202 ± 0.009
0.801HisMet: 0.801 ± 0.869
0.0HisAsn: 0.0 ± 0.0
0.401HisPro: 0.401 ± 0.222
1.202HisGln: 1.202 ± 0.009
0.0HisArg: 0.0 ± 0.0
2.404HisSer: 2.404 ± 0.018
0.801HisThr: 0.801 ± 0.444
1.603HisVal: 1.603 ± 0.231
0.401HisTrp: 0.401 ± 0.222
0.401HisTyr: 0.401 ± 0.222
0.0HisXaa: 0.0 ± 0.0
Ile
3.606IleAla: 3.606 ± 1.34
0.401IleCys: 0.401 ± 0.435
1.202IleAsp: 1.202 ± 0.009
4.407IleGlu: 4.407 ± 1.784
1.202IlePhe: 1.202 ± 0.009
4.407IleGly: 4.407 ± 1.499
0.401IleHis: 0.401 ± 0.222
2.804IleIle: 2.804 ± 0.24
2.404IleLys: 2.404 ± 1.331
4.407IleLeu: 4.407 ± 1.127
1.202IleMet: 1.202 ± 0.666
2.804IleAsn: 2.804 ± 0.896
3.606IlePro: 3.606 ± 1.942
1.202IleGln: 1.202 ± 0.666
2.404IleArg: 2.404 ± 0.638
3.205IleSer: 3.205 ± 0.462
4.808IleThr: 4.808 ± 0.62
2.404IleVal: 2.404 ± 0.675
0.801IleTrp: 0.801 ± 0.444
2.404IleTyr: 2.404 ± 1.295
0.0IleXaa: 0.0 ± 0.0
Lys
5.208LysAla: 5.208 ± 0.915
1.202LysCys: 1.202 ± 0.009
3.606LysAsp: 3.606 ± 1.34
4.808LysGlu: 4.808 ± 2.662
2.804LysPhe: 2.804 ± 0.416
2.404LysGly: 2.404 ± 0.018
1.202LysHis: 1.202 ± 0.009
3.606LysIle: 3.606 ± 0.027
1.202LysLys: 1.202 ± 0.666
6.41LysLeu: 6.41 ± 1.58
1.603LysMet: 1.603 ± 0.887
1.202LysAsn: 1.202 ± 0.666
2.404LysPro: 2.404 ± 0.018
1.202LysGln: 1.202 ± 0.009
2.404LysArg: 2.404 ± 1.331
3.205LysSer: 3.205 ± 0.462
3.205LysThr: 3.205 ± 1.118
2.804LysVal: 2.804 ± 1.553
0.401LysTrp: 0.401 ± 0.222
0.801LysTyr: 0.801 ± 0.213
0.0LysXaa: 0.0 ± 0.0
Leu
6.41LeuAla: 6.41 ± 1.702
2.404LeuCys: 2.404 ± 0.675
5.208LeuAsp: 5.208 ± 0.258
3.606LeuGlu: 3.606 ± 0.684
2.003LeuPhe: 2.003 ± 0.453
6.01LeuGly: 6.01 ± 1.358
1.603LeuHis: 1.603 ± 0.231
3.606LeuIle: 3.606 ± 0.684
8.413LeuLys: 8.413 ± 0.72
3.205LeuLeu: 3.205 ± 0.462
2.003LeuMet: 2.003 ± 0.86
2.404LeuAsn: 2.404 ± 0.675
3.205LeuPro: 3.205 ± 0.195
4.407LeuGln: 4.407 ± 1.127
3.205LeuArg: 3.205 ± 1.118
6.41LeuSer: 6.41 ± 3.672
9.215LeuThr: 9.215 ± 0.806
6.01LeuVal: 6.01 ± 1.358
0.801LeuTrp: 0.801 ± 0.213
1.202LeuTyr: 1.202 ± 0.009
0.0LeuXaa: 0.0 ± 0.0
Met
1.603MetAla: 1.603 ± 0.231
0.0MetCys: 0.0 ± 0.0
2.003MetAsp: 2.003 ± 1.109
2.003MetGlu: 2.003 ± 0.453
2.003MetPhe: 2.003 ± 1.109
0.0MetGly: 0.0 ± 0.0
0.0MetHis: 0.0 ± 0.0
1.603MetIle: 1.603 ± 0.887
2.804MetLys: 2.804 ± 0.896
2.804MetLeu: 2.804 ± 0.24
2.003MetMet: 2.003 ± 0.453
1.603MetAsn: 1.603 ± 0.426
1.603MetPro: 1.603 ± 0.887
1.202MetGln: 1.202 ± 0.009
2.003MetArg: 2.003 ± 1.109
1.202MetSer: 1.202 ± 1.304
3.205MetThr: 3.205 ± 1.775
2.404MetVal: 2.404 ± 1.295
0.801MetTrp: 0.801 ± 0.444
2.003MetTyr: 2.003 ± 0.453
0.0MetXaa: 0.0 ± 0.0
Asn
4.808AsnAla: 4.808 ± 1.277
0.801AsnCys: 0.801 ± 0.213
0.801AsnAsp: 0.801 ± 0.213
2.804AsnGlu: 2.804 ± 0.896
2.804AsnPhe: 2.804 ± 0.24
2.804AsnGly: 2.804 ± 0.24
0.801AsnHis: 0.801 ± 0.213
1.603AsnIle: 1.603 ± 0.231
2.404AsnLys: 2.404 ± 0.638
3.606AsnLeu: 3.606 ± 2.599
2.003AsnMet: 2.003 ± 1.109
3.205AsnAsn: 3.205 ± 0.195
2.003AsnPro: 2.003 ± 0.204
1.202AsnGln: 1.202 ± 0.666
2.804AsnArg: 2.804 ± 1.553
2.804AsnSer: 2.804 ± 0.24
5.208AsnThr: 5.208 ± 1.711
3.606AsnVal: 3.606 ± 0.629
0.801AsnTrp: 0.801 ± 0.444
0.401AsnTyr: 0.401 ± 0.222
0.0AsnXaa: 0.0 ± 0.0
Pro
1.603ProAla: 1.603 ± 0.426
0.801ProCys: 0.801 ± 0.444
0.801ProAsp: 0.801 ± 0.213
1.603ProGlu: 1.603 ± 0.426
2.003ProPhe: 2.003 ± 1.517
5.208ProGly: 5.208 ± 0.398
0.401ProHis: 0.401 ± 0.222
3.205ProIle: 3.205 ± 0.195
3.606ProLys: 3.606 ± 1.34
5.208ProLeu: 5.208 ± 0.398
1.202ProMet: 1.202 ± 0.009
2.804ProAsn: 2.804 ± 2.386
1.202ProPro: 1.202 ± 0.647
0.0ProGln: 0.0 ± 0.0
2.003ProArg: 2.003 ± 0.204
2.404ProSer: 2.404 ± 0.638
3.205ProThr: 3.205 ± 1.508
5.208ProVal: 5.208 ± 0.258
1.202ProTrp: 1.202 ± 0.009
0.401ProTyr: 0.401 ± 0.222
0.0ProXaa: 0.0 ± 0.0
Gln
2.404GlnAla: 2.404 ± 0.675
0.401GlnCys: 0.401 ± 0.435
1.202GlnAsp: 1.202 ± 0.647
2.404GlnGlu: 2.404 ± 1.331
2.404GlnPhe: 2.404 ± 0.675
2.003GlnGly: 2.003 ± 0.204
0.801GlnHis: 0.801 ± 0.444
1.202GlnIle: 1.202 ± 0.009
2.003GlnLys: 2.003 ± 1.109
2.003GlnLeu: 2.003 ± 1.109
0.401GlnMet: 0.401 ± 0.222
2.404GlnAsn: 2.404 ± 1.331
1.202GlnPro: 1.202 ± 0.666
1.202GlnGln: 1.202 ± 0.666
2.003GlnArg: 2.003 ± 0.453
3.205GlnSer: 3.205 ± 2.164
2.804GlnThr: 2.804 ± 0.896
2.003GlnVal: 2.003 ± 0.453
0.401GlnTrp: 0.401 ± 0.222
2.804GlnTyr: 2.804 ± 0.896
0.0GlnXaa: 0.0 ± 0.0
Arg
2.003ArgAla: 2.003 ± 0.453
0.801ArgCys: 0.801 ± 0.444
2.003ArgAsp: 2.003 ± 0.204
3.205ArgGlu: 3.205 ± 1.775
4.407ArgPhe: 4.407 ± 0.471
4.407ArgGly: 4.407 ± 0.186
1.202ArgHis: 1.202 ± 0.666
1.202ArgIle: 1.202 ± 0.009
3.205ArgLys: 3.205 ± 1.775
4.407ArgLeu: 4.407 ± 1.784
2.003ArgMet: 2.003 ± 0.204
3.606ArgAsn: 3.606 ± 0.027
2.003ArgPro: 2.003 ± 0.204
2.003ArgGln: 2.003 ± 1.109
1.603ArgArg: 1.603 ± 0.231
4.006ArgSer: 4.006 ± 1.064
2.003ArgThr: 2.003 ± 0.204
4.808ArgVal: 4.808 ± 1.277
0.801ArgTrp: 0.801 ± 0.444
2.404ArgTyr: 2.404 ± 1.295
0.0ArgXaa: 0.0 ± 0.0
Ser
6.811SerAla: 6.811 ± 0.167
0.401SerCys: 0.401 ± 0.222
2.804SerAsp: 2.804 ± 0.24
4.006SerGlu: 4.006 ± 0.407
4.808SerPhe: 4.808 ± 1.277
4.808SerGly: 4.808 ± 1.277
0.401SerHis: 0.401 ± 0.222
2.003SerIle: 2.003 ± 0.86
2.804SerLys: 2.804 ± 0.24
6.01SerLeu: 6.01 ± 1.268
1.603SerMet: 1.603 ± 0.426
1.603SerAsn: 1.603 ± 0.426
3.205SerPro: 3.205 ± 1.118
2.003SerGln: 2.003 ± 0.453
4.808SerArg: 4.808 ± 0.62
2.003SerSer: 2.003 ± 2.173
5.609SerThr: 5.609 ± 2.802
6.41SerVal: 6.41 ± 2.359
0.801SerTrp: 0.801 ± 0.444
1.603SerTyr: 1.603 ± 1.082
0.0SerXaa: 0.0 ± 0.0
Thr
7.212ThrAla: 7.212 ± 0.602
1.202ThrCys: 1.202 ± 0.009
4.407ThrAsp: 4.407 ± 0.186
4.006ThrGlu: 4.006 ± 1.064
4.407ThrPhe: 4.407 ± 0.471
8.413ThrGly: 8.413 ± 1.906
0.801ThrHis: 0.801 ± 0.213
2.404ThrIle: 2.404 ± 0.018
2.804ThrLys: 2.804 ± 0.24
6.01ThrLeu: 6.01 ± 1.268
1.603ThrMet: 1.603 ± 0.231
3.606ThrAsn: 3.606 ± 1.286
4.407ThrPro: 4.407 ± 0.186
4.006ThrGln: 4.006 ± 0.249
2.003ThrArg: 2.003 ± 0.204
3.205ThrSer: 3.205 ± 0.195
7.612ThrThr: 7.612 ± 4.976
3.606ThrVal: 3.606 ± 0.629
1.202ThrTrp: 1.202 ± 0.009
1.603ThrTyr: 1.603 ± 0.231
0.0ThrXaa: 0.0 ± 0.0
Val
8.814ValAla: 8.814 ± 0.371
1.603ValCys: 1.603 ± 0.426
3.205ValAsp: 3.205 ± 1.118
3.205ValGlu: 3.205 ± 0.195
3.205ValPhe: 3.205 ± 0.195
7.212ValGly: 7.212 ± 0.711
2.003ValHis: 2.003 ± 0.453
3.205ValIle: 3.205 ± 0.195
2.804ValLys: 2.804 ± 0.896
4.407ValLeu: 4.407 ± 2.155
1.603ValMet: 1.603 ± 0.887
3.606ValAsn: 3.606 ± 0.027
5.609ValPro: 5.609 ± 3.459
2.404ValGln: 2.404 ± 0.675
4.808ValArg: 4.808 ± 0.036
4.407ValSer: 4.407 ± 1.499
4.006ValThr: 4.006 ± 0.249
6.41ValVal: 6.41 ± 2.359
2.003ValTrp: 2.003 ± 0.204
0.801ValTyr: 0.801 ± 0.213
0.0ValXaa: 0.0 ± 0.0
Trp
0.401TrpAla: 0.401 ± 0.222
0.401TrpCys: 0.401 ± 0.222
0.801TrpAsp: 0.801 ± 0.213
0.401TrpGlu: 0.401 ± 0.222
1.202TrpPhe: 1.202 ± 0.647
0.0TrpGly: 0.0 ± 0.0
0.801TrpHis: 0.801 ± 0.444
1.603TrpIle: 1.603 ± 0.231
1.202TrpLys: 1.202 ± 0.666
1.202TrpLeu: 1.202 ± 0.009
0.401TrpMet: 0.401 ± 0.142
1.202TrpAsn: 1.202 ± 0.666
0.0TrpPro: 0.0 ± 0.0
0.801TrpGln: 0.801 ± 0.213
1.202TrpArg: 1.202 ± 0.009
1.202TrpSer: 1.202 ± 0.666
0.401TrpThr: 0.401 ± 0.222
1.202TrpVal: 1.202 ± 0.666
0.0TrpTrp: 0.0 ± 0.0
1.603TrpTyr: 1.603 ± 0.231
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.202TyrAla: 1.202 ± 1.304
0.401TyrCys: 0.401 ± 0.435
2.003TyrAsp: 2.003 ± 0.204
1.202TyrGlu: 1.202 ± 0.666
1.202TyrPhe: 1.202 ± 0.647
0.801TyrGly: 0.801 ± 0.869
0.401TyrHis: 0.401 ± 0.222
3.606TyrIle: 3.606 ± 0.027
1.202TyrLys: 1.202 ± 0.666
2.003TyrLeu: 2.003 ± 0.86
0.401TyrMet: 0.401 ± 0.435
0.401TyrAsn: 0.401 ± 0.222
1.202TyrPro: 1.202 ± 0.647
0.801TyrGln: 0.801 ± 0.444
2.404TyrArg: 2.404 ± 0.018
2.404TyrSer: 2.404 ± 0.638
3.606TyrThr: 3.606 ± 0.027
3.606TyrVal: 3.606 ± 0.629
1.603TyrTrp: 1.603 ± 0.231
0.801TyrTyr: 0.801 ± 0.213
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2497 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski