Amino acid dipepetide frequency for Sediminibacterium ginsengisoli

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.886AlaAla: 8.886 ± 0.134	0.79AlaCys: 0.79 ± 0.031	4.826AlaAsp: 4.826 ± 0.069	4.729AlaGlu: 4.729 ± 0.072	3.734AlaPhe: 3.734 ± 0.061	7.093AlaGly: 7.093 ± 0.114	1.321AlaHis: 1.321 ± 0.037	5.352AlaIle: 5.352 ± 0.079	4.307AlaLys: 4.307 ± 0.07	7.308AlaLeu: 7.308 ± 0.093	1.982AlaMet: 1.982 ± 0.043	3.549AlaAsn: 3.549 ± 0.1	2.781AlaPro: 2.781 ± 0.065	3.017AlaGln: 3.017 ± 0.063	3.272AlaArg: 3.272 ± 0.057	4.912AlaSer: 4.912 ± 0.087	4.72AlaThr: 4.72 ± 0.104	5.858AlaVal: 5.858 ± 0.073	0.891AlaTrp: 0.891 ± 0.03	2.969AlaTyr: 2.969 ± 0.05	0.0AlaXaa: 0.0 ± 0.0
Cys	0.646CysAla: 0.646 ± 0.039	0.157CysCys: 0.157 ± 0.012	0.403CysAsp: 0.403 ± 0.02	0.404CysGlu: 0.404 ± 0.02	0.466CysPhe: 0.466 ± 0.023	0.696CysGly: 0.696 ± 0.024	0.194CysHis: 0.194 ± 0.015	0.716CysIle: 0.716 ± 0.027	0.441CysLys: 0.441 ± 0.018	0.811CysLeu: 0.811 ± 0.026	0.236CysMet: 0.236 ± 0.014	0.462CysAsn: 0.462 ± 0.021	0.362CysPro: 0.362 ± 0.02	0.218CysGln: 0.218 ± 0.014	0.445CysArg: 0.445 ± 0.022	0.636CysSer: 0.636 ± 0.034	0.513CysThr: 0.513 ± 0.025	0.523CysVal: 0.523 ± 0.021	0.109CysTrp: 0.109 ± 0.01	0.39CysTyr: 0.39 ± 0.02	0.0CysXaa: 0.0 ± 0.0
Asp	4.363AspAla: 4.363 ± 0.08	0.412AspCys: 0.412 ± 0.02	2.305AspAsp: 2.305 ± 0.059	3.197AspGlu: 3.197 ± 0.062	2.562AspPhe: 2.562 ± 0.055	3.489AspGly: 3.489 ± 0.066	1.075AspHis: 1.075 ± 0.029	3.783AspIle: 3.783 ± 0.06	3.519AspLys: 3.519 ± 0.071	4.587AspLeu: 4.587 ± 0.064	1.295AspMet: 1.295 ± 0.035	2.499AspAsn: 2.499 ± 0.047	2.162AspPro: 2.162 ± 0.044	1.615AspGln: 1.615 ± 0.038	2.162AspArg: 2.162 ± 0.045	3.155AspSer: 3.155 ± 0.083	3.104AspThr: 3.104 ± 0.098	3.301AspVal: 3.301 ± 0.058	0.679AspTrp: 0.679 ± 0.024	2.282AspTyr: 2.282 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	4.48GluAla: 4.48 ± 0.076	0.366GluCys: 0.366 ± 0.018	2.648GluAsp: 2.648 ± 0.05	3.81GluGlu: 3.81 ± 0.082	2.13GluPhe: 2.13 ± 0.047	3.225GluGly: 3.225 ± 0.061	1.115GluHis: 1.115 ± 0.035	3.874GluIle: 3.874 ± 0.072	5.142GluLys: 5.142 ± 0.083	5.695GluLeu: 5.695 ± 0.097	1.604GluMet: 1.604 ± 0.042	2.857GluAsn: 2.857 ± 0.057	1.725GluPro: 1.725 ± 0.037	2.741GluGln: 2.741 ± 0.059	2.606GluArg: 2.606 ± 0.052	2.652GluSer: 2.652 ± 0.045	3.114GluThr: 3.114 ± 0.052	3.408GluVal: 3.408 ± 0.061	0.733GluTrp: 0.733 ± 0.027	1.943GluTyr: 1.943 ± 0.047	0.0GluXaa: 0.0 ± 0.0
Phe	3.514PheAla: 3.514 ± 0.057	0.497PheCys: 0.497 ± 0.022	2.524PheAsp: 2.524 ± 0.054	2.476PheGlu: 2.476 ± 0.044	2.432PhePhe: 2.432 ± 0.057	3.207PheGly: 3.207 ± 0.05	0.823PheHis: 0.823 ± 0.025	3.283PheIle: 3.283 ± 0.064	2.472PheLys: 2.472 ± 0.052	4.124PheLeu: 4.124 ± 0.069	1.103PheMet: 1.103 ± 0.027	2.678PheAsn: 2.678 ± 0.051	1.694PhePro: 1.694 ± 0.039	1.292PheGln: 1.292 ± 0.036	2.412PheArg: 2.412 ± 0.047	3.77PheSer: 3.77 ± 0.071	3.25PheThr: 3.25 ± 0.056	2.686PheVal: 2.686 ± 0.051	0.545PheTrp: 0.545 ± 0.021	1.91PheTyr: 1.91 ± 0.038	0.0PheXaa: 0.0 ± 0.0
Gly	4.858GlyAla: 4.858 ± 0.088	0.731GlyCys: 0.731 ± 0.031	3.316GlyAsp: 3.316 ± 0.068	3.271GlyGlu: 3.271 ± 0.062	3.504GlyPhe: 3.504 ± 0.056	5.207GlyGly: 5.207 ± 0.102	1.19GlyHis: 1.19 ± 0.034	5.426GlyIle: 5.426 ± 0.068	5.403GlyLys: 5.403 ± 0.07	6.024GlyLeu: 6.024 ± 0.076	1.995GlyMet: 1.995 ± 0.048	3.964GlyAsn: 3.964 ± 0.081	1.601GlyPro: 1.601 ± 0.044	2.254GlyGln: 2.254 ± 0.048	2.986GlyArg: 2.986 ± 0.057	4.664GlySer: 4.664 ± 0.088	4.492GlyThr: 4.492 ± 0.127	4.254GlyVal: 4.254 ± 0.064	1.012GlyTrp: 1.012 ± 0.029	3.107GlyTyr: 3.107 ± 0.061	0.0GlyXaa: 0.0 ± 0.0
His	1.47HisAla: 1.47 ± 0.041	0.216HisCys: 0.216 ± 0.013	0.876HisAsp: 0.876 ± 0.029	0.997HisGlu: 0.997 ± 0.03	1.182HisPhe: 1.182 ± 0.038	1.115HisGly: 1.115 ± 0.032	0.561HisHis: 0.561 ± 0.026	1.428HisIle: 1.428 ± 0.037	0.978HisLys: 0.978 ± 0.032	1.816HisLeu: 1.816 ± 0.045	0.38HisMet: 0.38 ± 0.019	0.848HisAsn: 0.848 ± 0.027	1.014HisPro: 1.014 ± 0.03	0.691HisGln: 0.691 ± 0.024	0.89HisArg: 0.89 ± 0.03	1.155HisSer: 1.155 ± 0.033	1.156HisThr: 1.156 ± 0.035	1.033HisVal: 1.033 ± 0.029	0.231HisTrp: 0.231 ± 0.014	0.916HisTyr: 0.916 ± 0.025	0.0HisXaa: 0.0 ± 0.0
Ile	5.839IleAla: 5.839 ± 0.077	0.761IleCys: 0.761 ± 0.026	3.789IleAsp: 3.789 ± 0.062	3.734IleGlu: 3.734 ± 0.075	2.726IlePhe: 2.726 ± 0.056	4.591IleGly: 4.591 ± 0.075	1.307IleHis: 1.307 ± 0.035	4.338IleIle: 4.338 ± 0.07	3.749IleLys: 3.749 ± 0.068	5.84IleLeu: 5.84 ± 0.091	1.371IleMet: 1.371 ± 0.034	3.596IleAsn: 3.596 ± 0.061	3.086IlePro: 3.086 ± 0.052	2.214IleGln: 2.214 ± 0.037	3.913IleArg: 3.913 ± 0.066	4.94IleSer: 4.94 ± 0.061	4.61IleThr: 4.61 ± 0.076	4.189IleVal: 4.189 ± 0.066	0.677IleTrp: 0.677 ± 0.027	2.359IleTyr: 2.359 ± 0.044	0.0IleXaa: 0.0 ± 0.0
Lys	5.319LysAla: 5.319 ± 0.08	0.334LysCys: 0.334 ± 0.016	3.821LysAsp: 3.821 ± 0.068	4.567LysGlu: 4.567 ± 0.089	2.046LysPhe: 2.046 ± 0.045	4.406LysGly: 4.406 ± 0.068	1.118LysHis: 1.118 ± 0.032	4.194LysIle: 4.194 ± 0.06	5.455LysLys: 5.455 ± 0.101	5.634LysLeu: 5.634 ± 0.093	1.861LysMet: 1.861 ± 0.039	3.515LysAsn: 3.515 ± 0.06	2.578LysPro: 2.578 ± 0.043	2.917LysGln: 2.917 ± 0.052	2.735LysArg: 2.735 ± 0.046	3.486LysSer: 3.486 ± 0.064	3.92LysThr: 3.92 ± 0.067	3.854LysVal: 3.854 ± 0.062	0.832LysTrp: 0.832 ± 0.029	2.277LysTyr: 2.277 ± 0.05	0.0LysXaa: 0.0 ± 0.0
Leu	7.482LeuAla: 7.482 ± 0.102	0.899LeuCys: 0.899 ± 0.029	4.463LeuAsp: 4.463 ± 0.098	4.89LeuGlu: 4.89 ± 0.08	4.784LeuPhe: 4.784 ± 0.075	5.484LeuGly: 5.484 ± 0.078	1.882LeuHis: 1.882 ± 0.043	5.725LeuIle: 5.725 ± 0.088	6.171LeuLys: 6.171 ± 0.089	10.337LeuLeu: 10.337 ± 0.148	2.205LeuMet: 2.205 ± 0.045	5.095LeuAsn: 5.095 ± 0.088	4.296LeuPro: 4.296 ± 0.065	4.369LeuGln: 4.369 ± 0.075	4.287LeuArg: 4.287 ± 0.068	6.747LeuSer: 6.747 ± 0.094	5.292LeuThr: 5.292 ± 0.071	5.826LeuVal: 5.826 ± 0.08	0.91LeuTrp: 0.91 ± 0.028	3.264LeuTyr: 3.264 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	1.954MetAla: 1.954 ± 0.045	0.149MetCys: 0.149 ± 0.01	1.22MetAsp: 1.22 ± 0.033	1.46MetGlu: 1.46 ± 0.035	0.884MetPhe: 0.884 ± 0.029	1.501MetGly: 1.501 ± 0.036	0.514MetHis: 0.514 ± 0.022	1.659MetIle: 1.659 ± 0.037	2.125MetLys: 2.125 ± 0.041	2.534MetLeu: 2.534 ± 0.098	0.71MetMet: 0.71 ± 0.027	1.342MetAsn: 1.342 ± 0.035	1.194MetPro: 1.194 ± 0.03	1.244MetGln: 1.244 ± 0.035	1.244MetArg: 1.244 ± 0.031	1.441MetSer: 1.441 ± 0.036	1.157MetThr: 1.157 ± 0.027	1.425MetVal: 1.425 ± 0.036	0.191MetTrp: 0.191 ± 0.012	0.705MetTyr: 0.705 ± 0.025	0.0MetXaa: 0.0 ± 0.0
Asn	4.073AsnAla: 4.073 ± 0.068	0.443AsnCys: 0.443 ± 0.025	2.691AsnAsp: 2.691 ± 0.043	2.742AsnGlu: 2.742 ± 0.057	2.064AsnPhe: 2.064 ± 0.041	4.148AsnGly: 4.148 ± 0.084	0.895AsnHis: 0.895 ± 0.027	3.825AsnIle: 3.825 ± 0.061	3.097AsnLys: 3.097 ± 0.056	4.275AsnLeu: 4.275 ± 0.065	1.266AsnMet: 1.266 ± 0.036	3.239AsnAsn: 3.239 ± 0.079	2.583AsnPro: 2.583 ± 0.059	1.702AsnGln: 1.702 ± 0.039	2.618AsnArg: 2.618 ± 0.048	2.969AsnSer: 2.969 ± 0.059	3.572AsnThr: 3.572 ± 0.127	2.966AsnVal: 2.966 ± 0.069	0.782AsnTrp: 0.782 ± 0.031	2.339AsnTyr: 2.339 ± 0.067	0.0AsnXaa: 0.0 ± 0.0
Pro	4.388ProAla: 4.388 ± 0.079	0.274ProCys: 0.274 ± 0.017	2.591ProAsp: 2.591 ± 0.053	2.79ProGlu: 2.79 ± 0.05	1.943ProPhe: 1.943 ± 0.045	3.287ProGly: 3.287 ± 0.06	0.738ProHis: 0.738 ± 0.027	1.715ProIle: 1.715 ± 0.034	1.862ProLys: 1.862 ± 0.047	3.437ProLeu: 3.437 ± 0.048	0.833ProMet: 0.833 ± 0.028	1.508ProAsn: 1.508 ± 0.043	1.208ProPro: 1.208 ± 0.044	1.434ProGln: 1.434 ± 0.033	1.277ProArg: 1.277 ± 0.037	2.145ProSer: 2.145 ± 0.048	1.666ProThr: 1.666 ± 0.041	4.069ProVal: 4.069 ± 0.082	0.4ProTrp: 0.4 ± 0.02	1.618ProTyr: 1.618 ± 0.039	0.0ProXaa: 0.0 ± 0.0
Gln	3.053GlnAla: 3.053 ± 0.052	0.201GlnCys: 0.201 ± 0.013	1.645GlnAsp: 1.645 ± 0.042	2.161GlnGlu: 2.161 ± 0.047	1.78GlnPhe: 1.78 ± 0.041	2.102GlnGly: 2.102 ± 0.041	0.886GlnHis: 0.886 ± 0.029	2.062GlnIle: 2.062 ± 0.046	2.492GlnLys: 2.492 ± 0.054	4.628GlnLeu: 4.628 ± 0.071	0.94GlnMet: 0.94 ± 0.028	1.658GlnAsn: 1.658 ± 0.036	1.728GlnPro: 1.728 ± 0.038	2.644GlnGln: 2.644 ± 0.063	1.85GlnArg: 1.85 ± 0.051	2.214GlnSer: 2.214 ± 0.054	2.032GlnThr: 2.032 ± 0.048	2.606GlnVal: 2.606 ± 0.051	0.494GlnTrp: 0.494 ± 0.023	1.653GlnTyr: 1.653 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	2.592ArgAla: 2.592 ± 0.044	0.303ArgCys: 0.303 ± 0.018	2.129ArgAsp: 2.129 ± 0.051	2.662ArgGlu: 2.662 ± 0.052	2.508ArgPhe: 2.508 ± 0.052	2.247ArgGly: 2.247 ± 0.05	0.884ArgHis: 0.884 ± 0.033	3.818ArgIle: 3.818 ± 0.06	3.543ArgLys: 3.543 ± 0.061	4.462ArgLeu: 4.462 ± 0.085	1.356ArgMet: 1.356 ± 0.037	2.848ArgAsn: 2.848 ± 0.054	1.574ArgPro: 1.574 ± 0.035	1.989ArgGln: 1.989 ± 0.045	2.02ArgArg: 2.02 ± 0.049	2.774ArgSer: 2.774 ± 0.052	2.474ArgThr: 2.474 ± 0.044	2.51ArgVal: 2.51 ± 0.046	0.676ArgTrp: 0.676 ± 0.031	2.137ArgTyr: 2.137 ± 0.042	0.0ArgXaa: 0.0 ± 0.0
Ser	5.011SerAla: 5.011 ± 0.07	0.624SerCys: 0.624 ± 0.027	3.075SerAsp: 3.075 ± 0.062	2.917SerGlu: 2.917 ± 0.057	3.799SerPhe: 3.799 ± 0.064	5.27SerGly: 5.27 ± 0.093	1.083SerHis: 1.083 ± 0.031	4.273SerIle: 4.273 ± 0.061	3.412SerLys: 3.412 ± 0.062	6.285SerLeu: 6.285 ± 0.094	1.5SerMet: 1.5 ± 0.037	3.175SerAsn: 3.175 ± 0.087	2.232SerPro: 2.232 ± 0.048	2.008SerGln: 2.008 ± 0.072	2.867SerArg: 2.867 ± 0.049	4.006SerSer: 4.006 ± 0.087	3.366SerThr: 3.366 ± 0.083	4.329SerVal: 4.329 ± 0.064	0.873SerTrp: 0.873 ± 0.029	2.722SerTyr: 2.722 ± 0.052	0.0SerXaa: 0.0 ± 0.0
Thr	5.792ThrAla: 5.792 ± 0.136	0.438ThrCys: 0.438 ± 0.02	3.497ThrAsp: 3.497 ± 0.054	3.157ThrGlu: 3.157 ± 0.056	2.46ThrPhe: 2.46 ± 0.044	5.445ThrGly: 5.445 ± 0.111	1.007ThrHis: 1.007 ± 0.032	4.202ThrIle: 4.202 ± 0.086	2.883ThrLys: 2.883 ± 0.079	5.282ThrLeu: 5.282 ± 0.073	1.186ThrMet: 1.186 ± 0.036	2.687ThrAsn: 2.687 ± 0.061	2.699ThrPro: 2.699 ± 0.068	1.811ThrGln: 1.811 ± 0.046	2.558ThrArg: 2.558 ± 0.055	3.55ThrSer: 3.55 ± 0.08	3.762ThrThr: 3.762 ± 0.123	4.479ThrVal: 4.479 ± 0.118	0.701ThrTrp: 0.701 ± 0.034	2.341ThrTyr: 2.341 ± 0.075	0.0ThrXaa: 0.0 ± 0.0
Val	5.049ValAla: 5.049 ± 0.075	0.731ValCys: 0.731 ± 0.035	2.933ValAsp: 2.933 ± 0.054	3.148ValGlu: 3.148 ± 0.054	3.117ValPhe: 3.117 ± 0.051	3.329ValGly: 3.329 ± 0.065	1.18ValHis: 1.18 ± 0.034	4.792ValIle: 4.792 ± 0.071	4.529ValLys: 4.529 ± 0.068	6.259ValLeu: 6.259 ± 0.081	1.636ValMet: 1.636 ± 0.041	3.63ValAsn: 3.63 ± 0.062	2.64ValPro: 2.64 ± 0.049	2.484ValGln: 2.484 ± 0.088	2.612ValArg: 2.612 ± 0.048	4.441ValSer: 4.441 ± 0.071	4.492ValThr: 4.492 ± 0.138	4.281ValVal: 4.281 ± 0.081	0.682ValTrp: 0.682 ± 0.023	2.512ValTyr: 2.512 ± 0.046	0.0ValXaa: 0.0 ± 0.0
Trp	0.686TrpAla: 0.686 ± 0.025	0.14TrpCys: 0.14 ± 0.01	0.648TrpAsp: 0.648 ± 0.027	0.669TrpGlu: 0.669 ± 0.026	0.59TrpPhe: 0.59 ± 0.021	0.758TrpGly: 0.758 ± 0.027	0.274TrpHis: 0.274 ± 0.015	0.783TrpIle: 0.783 ± 0.028	0.895TrpLys: 0.895 ± 0.027	1.328TrpLeu: 1.328 ± 0.037	0.349TrpMet: 0.349 ± 0.018	0.744TrpAsn: 0.744 ± 0.028	0.34TrpPro: 0.34 ± 0.018	0.633TrpGln: 0.633 ± 0.023	0.554TrpArg: 0.554 ± 0.021	0.647TrpSer: 0.647 ± 0.024	0.639TrpThr: 0.639 ± 0.032	0.725TrpVal: 0.725 ± 0.028	0.224TrpTrp: 0.224 ± 0.013	0.507TrpTyr: 0.507 ± 0.023	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.841TyrAla: 2.841 ± 0.051	0.362TyrCys: 0.362 ± 0.017	2.144TyrAsp: 2.144 ± 0.048	2.087TyrGlu: 2.087 ± 0.041	1.978TyrPhe: 1.978 ± 0.046	2.661TyrGly: 2.661 ± 0.048	0.908TyrHis: 0.908 ± 0.029	2.383TyrIle: 2.383 ± 0.043	2.391TyrLys: 2.391 ± 0.048	3.743TyrLeu: 3.743 ± 0.082	0.845TyrMet: 0.845 ± 0.027	2.394TyrAsn: 2.394 ± 0.049	1.685TyrPro: 1.685 ± 0.037	1.553TyrGln: 1.553 ± 0.032	2.196TyrArg: 2.196 ± 0.049	2.527TyrSer: 2.527 ± 0.044	2.607TyrThr: 2.607 ± 0.067	2.153TyrVal: 2.153 ± 0.038	0.494TyrTrp: 0.494 ± 0.021	1.861TyrTyr: 1.861 ± 0.045	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3581 proteins (1239871 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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