Amino acid dipepetide frequency for Pseudolabrys taiwanensis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	18.24AlaAla: 18.24 ± 0.151	1.08AlaCys: 1.08 ± 0.026	6.806AlaAsp: 6.806 ± 0.079	7.049AlaGlu: 7.049 ± 0.089	4.689AlaPhe: 4.689 ± 0.065	10.411AlaGly: 10.411 ± 0.108	2.309AlaHis: 2.309 ± 0.042	6.538AlaIle: 6.538 ± 0.087	5.11AlaLys: 5.11 ± 0.063	13.835AlaLeu: 13.835 ± 0.127	3.455AlaMet: 3.455 ± 0.047	3.081AlaAsn: 3.081 ± 0.066	6.123AlaPro: 6.123 ± 0.076	4.391AlaGln: 4.391 ± 0.06	8.694AlaArg: 8.694 ± 0.109	6.169AlaSer: 6.169 ± 0.073	6.321AlaThr: 6.321 ± 0.087	9.42AlaVal: 9.42 ± 0.093	1.5AlaTrp: 1.5 ± 0.033	2.678AlaTyr: 2.678 ± 0.055	0.0AlaXaa: 0.0 ± 0.0
Cys	0.988CysAla: 0.988 ± 0.027	0.112CysCys: 0.112 ± 0.008	0.482CysAsp: 0.482 ± 0.018	0.418CysGlu: 0.418 ± 0.017	0.315CysPhe: 0.315 ± 0.015	0.92CysGly: 0.92 ± 0.025	0.22CysHis: 0.22 ± 0.014	0.416CysIle: 0.416 ± 0.019	0.211CysLys: 0.211 ± 0.012	0.76CysLeu: 0.76 ± 0.025	0.171CysMet: 0.171 ± 0.01	0.214CysAsn: 0.214 ± 0.012	0.41CysPro: 0.41 ± 0.015	0.21CysGln: 0.21 ± 0.012	0.6CysArg: 0.6 ± 0.017	0.397CysSer: 0.397 ± 0.014	0.423CysThr: 0.423 ± 0.015	0.644CysVal: 0.644 ± 0.02	0.098CysTrp: 0.098 ± 0.007	0.224CysTyr: 0.224 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	6.703AspAla: 6.703 ± 0.074	0.472AspCys: 0.472 ± 0.019	2.945AspAsp: 2.945 ± 0.045	3.219AspGlu: 3.219 ± 0.057	2.175AspPhe: 2.175 ± 0.044	4.706AspGly: 4.706 ± 0.064	1.117AspHis: 1.117 ± 0.029	3.15AspIle: 3.15 ± 0.047	2.182AspLys: 2.182 ± 0.044	5.564AspLeu: 5.564 ± 0.062	1.232AspMet: 1.232 ± 0.025	1.377AspAsn: 1.377 ± 0.032	3.146AspPro: 3.146 ± 0.045	1.519AspGln: 1.519 ± 0.031	3.915AspArg: 3.915 ± 0.06	2.043AspSer: 2.043 ± 0.039	2.607AspThr: 2.607 ± 0.041	4.502AspVal: 4.502 ± 0.06	0.898AspTrp: 0.898 ± 0.026	1.543AspTyr: 1.543 ± 0.041	0.0AspXaa: 0.0 ± 0.0
Glu	6.874GluAla: 6.874 ± 0.092	0.348GluCys: 0.348 ± 0.017	2.323GluAsp: 2.323 ± 0.045	2.755GluGlu: 2.755 ± 0.06	1.757GluPhe: 1.757 ± 0.036	3.745GluGly: 3.745 ± 0.055	1.149GluHis: 1.149 ± 0.026	3.038GluIle: 3.038 ± 0.042	2.382GluLys: 2.382 ± 0.044	4.872GluLeu: 4.872 ± 0.063	1.464GluMet: 1.464 ± 0.029	1.437GluAsn: 1.437 ± 0.031	2.62GluPro: 2.62 ± 0.048	2.197GluGln: 2.197 ± 0.047	4.812GluArg: 4.812 ± 0.069	2.21GluSer: 2.21 ± 0.039	2.983GluThr: 2.983 ± 0.043	3.671GluVal: 3.671 ± 0.05	0.64GluTrp: 0.64 ± 0.019	1.014GluTyr: 1.014 ± 0.026	0.0GluXaa: 0.0 ± 0.0
Phe	4.88PheAla: 4.88 ± 0.06	0.387PheCys: 0.387 ± 0.014	2.549PheAsp: 2.549 ± 0.041	1.964PheGlu: 1.964 ± 0.037	1.465PhePhe: 1.465 ± 0.031	3.8PheGly: 3.8 ± 0.056	0.684PheHis: 0.684 ± 0.024	1.765PheIle: 1.765 ± 0.037	1.303PheLys: 1.303 ± 0.031	3.212PheLeu: 3.212 ± 0.056	0.855PheMet: 0.855 ± 0.023	1.119PheAsn: 1.119 ± 0.03	1.688PhePro: 1.688 ± 0.039	0.913PheGln: 0.913 ± 0.027	2.135PheArg: 2.135 ± 0.037	2.052PheSer: 2.052 ± 0.035	2.049PheThr: 2.049 ± 0.036	3.125PheVal: 3.125 ± 0.05	0.557PheTrp: 0.557 ± 0.021	0.917PheTyr: 0.917 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	9.618GlyAla: 9.618 ± 0.098	0.828GlyCys: 0.828 ± 0.021	4.217GlyAsp: 4.217 ± 0.067	4.203GlyGlu: 4.203 ± 0.052	3.625GlyPhe: 3.625 ± 0.051	7.293GlyGly: 7.293 ± 0.112	1.845GlyHis: 1.845 ± 0.03	4.576GlyIle: 4.576 ± 0.063	3.544GlyLys: 3.544 ± 0.052	8.506GlyLeu: 8.506 ± 0.094	2.176GlyMet: 2.176 ± 0.038	2.302GlyAsn: 2.302 ± 0.05	3.58GlyPro: 3.58 ± 0.051	2.675GlyGln: 2.675 ± 0.037	5.732GlyArg: 5.732 ± 0.068	4.377GlySer: 4.377 ± 0.08	4.767GlyThr: 4.767 ± 0.082	6.275GlyVal: 6.275 ± 0.071	1.296GlyTrp: 1.296 ± 0.027	2.417GlyTyr: 2.417 ± 0.043	0.0GlyXaa: 0.0 ± 0.0
His	2.384HisAla: 2.384 ± 0.044	0.205HisCys: 0.205 ± 0.01	1.125HisAsp: 1.125 ± 0.028	1.044HisGlu: 1.044 ± 0.024	0.835HisPhe: 0.835 ± 0.024	1.885HisGly: 1.885 ± 0.037	0.59HisHis: 0.59 ± 0.029	1.02HisIle: 1.02 ± 0.023	0.57HisLys: 0.57 ± 0.019	1.9HisLeu: 1.9 ± 0.034	0.467HisMet: 0.467 ± 0.016	0.502HisAsn: 0.502 ± 0.016	1.287HisPro: 1.287 ± 0.031	0.518HisGln: 0.518 ± 0.021	1.365HisArg: 1.365 ± 0.033	0.877HisSer: 0.877 ± 0.024	0.896HisThr: 0.896 ± 0.023	1.595HisVal: 1.595 ± 0.032	0.32HisTrp: 0.32 ± 0.016	0.597HisTyr: 0.597 ± 0.018	0.0HisXaa: 0.0 ± 0.0
Ile	7.785IleAla: 7.785 ± 0.081	0.457IleCys: 0.457 ± 0.017	3.753IleAsp: 3.753 ± 0.05	3.392IleGlu: 3.392 ± 0.051	1.65IlePhe: 1.65 ± 0.031	5.273IleGly: 5.273 ± 0.066	0.844IleHis: 0.844 ± 0.021	2.234IleIle: 2.234 ± 0.042	1.933IleLys: 1.933 ± 0.038	4.049IleLeu: 4.049 ± 0.052	1.003IleMet: 1.003 ± 0.024	1.564IleAsn: 1.564 ± 0.041	2.221IlePro: 2.221 ± 0.043	1.154IleGln: 1.154 ± 0.032	2.823IleArg: 2.823 ± 0.042	2.54IleSer: 2.54 ± 0.043	2.782IleThr: 2.782 ± 0.052	4.872IleVal: 4.872 ± 0.061	0.559IleTrp: 0.559 ± 0.02	1.223IleTyr: 1.223 ± 0.027	0.0IleXaa: 0.0 ± 0.0
Lys	4.832LysAla: 4.832 ± 0.067	0.183LysCys: 0.183 ± 0.012	2.096LysAsp: 2.096 ± 0.039	1.838LysGlu: 1.838 ± 0.044	1.138LysPhe: 1.138 ± 0.027	2.786LysGly: 2.786 ± 0.047	0.74LysHis: 0.74 ± 0.023	2.049LysIle: 2.049 ± 0.039	1.817LysLys: 1.817 ± 0.048	4.05LysLeu: 4.05 ± 0.059	0.969LysMet: 0.969 ± 0.027	1.057LysAsn: 1.057 ± 0.026	2.567LysPro: 2.567 ± 0.046	1.288LysGln: 1.288 ± 0.026	2.823LysArg: 2.823 ± 0.048	2.024LysSer: 2.024 ± 0.036	2.236LysThr: 2.236 ± 0.041	2.885LysVal: 2.885 ± 0.045	0.422LysTrp: 0.422 ± 0.017	0.708LysTyr: 0.708 ± 0.019	0.0LysXaa: 0.0 ± 0.0
Leu	13.472LeuAla: 13.472 ± 0.114	0.855LeuCys: 0.855 ± 0.025	5.57LeuAsp: 5.57 ± 0.061	4.577LeuGlu: 4.577 ± 0.057	3.53LeuPhe: 3.53 ± 0.059	8.112LeuGly: 8.112 ± 0.08	1.787LeuHis: 1.787 ± 0.036	5.084LeuIle: 5.084 ± 0.073	4.068LeuLys: 4.068 ± 0.055	9.141LeuLeu: 9.141 ± 0.114	2.331LeuMet: 2.331 ± 0.04	2.75LeuAsn: 2.75 ± 0.049	5.512LeuPro: 5.512 ± 0.069	2.659LeuGln: 2.659 ± 0.037	6.432LeuArg: 6.432 ± 0.075	6.021LeuSer: 6.021 ± 0.075	5.861LeuThr: 5.861 ± 0.11	7.44LeuVal: 7.44 ± 0.089	1.124LeuTrp: 1.124 ± 0.031	2.102LeuTyr: 2.102 ± 0.038	0.0LeuXaa: 0.0 ± 0.0
Met	2.986MetAla: 2.986 ± 0.046	0.164MetCys: 0.164 ± 0.011	1.004MetAsp: 1.004 ± 0.025	0.952MetGlu: 0.952 ± 0.024	0.752MetPhe: 0.752 ± 0.022	1.635MetGly: 1.635 ± 0.036	0.473MetHis: 0.473 ± 0.016	1.33MetIle: 1.33 ± 0.033	1.045MetLys: 1.045 ± 0.027	2.562MetLeu: 2.562 ± 0.044	0.664MetMet: 0.664 ± 0.022	0.727MetAsn: 0.727 ± 0.021	1.661MetPro: 1.661 ± 0.036	0.887MetGln: 0.887 ± 0.023	1.92MetArg: 1.92 ± 0.032	1.713MetSer: 1.713 ± 0.031	1.832MetThr: 1.832 ± 0.036	1.707MetVal: 1.707 ± 0.037	0.237MetTrp: 0.237 ± 0.014	0.375MetTyr: 0.375 ± 0.016	0.0MetXaa: 0.0 ± 0.0
Asn	3.506AsnAla: 3.506 ± 0.065	0.215AsnCys: 0.215 ± 0.011	1.5AsnAsp: 1.5 ± 0.035	1.342AsnGlu: 1.342 ± 0.027	1.052AsnPhe: 1.052 ± 0.028	2.594AsnGly: 2.594 ± 0.05	0.492AsnHis: 0.492 ± 0.02	1.414AsnIle: 1.414 ± 0.035	0.941AsnLys: 0.941 ± 0.023	2.627AsnLeu: 2.627 ± 0.05	0.633AsnMet: 0.633 ± 0.02	0.836AsnAsn: 0.836 ± 0.031	1.762AsnPro: 1.762 ± 0.031	0.732AsnGln: 0.732 ± 0.025	1.805AsnArg: 1.805 ± 0.04	1.219AsnSer: 1.219 ± 0.035	1.372AsnThr: 1.372 ± 0.036	2.299AsnVal: 2.299 ± 0.044	0.439AsnTrp: 0.439 ± 0.015	0.762AsnTyr: 0.762 ± 0.026	0.0AsnXaa: 0.0 ± 0.0
Pro	6.628ProAla: 6.628 ± 0.077	0.302ProCys: 0.302 ± 0.014	3.452ProAsp: 3.452 ± 0.051	3.22ProGlu: 3.22 ± 0.045	2.017ProPhe: 2.017 ± 0.033	4.477ProGly: 4.477 ± 0.061	1.133ProHis: 1.133 ± 0.029	2.502ProIle: 2.502 ± 0.04	2.058ProLys: 2.058 ± 0.038	4.827ProLeu: 4.827 ± 0.066	1.259ProMet: 1.259 ± 0.028	1.637ProAsn: 1.637 ± 0.036	3.062ProPro: 3.062 ± 0.069	1.845ProGln: 1.845 ± 0.036	3.181ProArg: 3.181 ± 0.056	2.844ProSer: 2.844 ± 0.046	2.79ProThr: 2.79 ± 0.038	4.186ProVal: 4.186 ± 0.06	0.7ProTrp: 0.7 ± 0.023	1.323ProTyr: 1.323 ± 0.031	0.0ProXaa: 0.0 ± 0.0
Gln	4.12GlnAla: 4.12 ± 0.06	0.227GlnCys: 0.227 ± 0.012	1.327GlnAsp: 1.327 ± 0.03	1.416GlnGlu: 1.416 ± 0.031	1.115GlnPhe: 1.115 ± 0.026	2.372GlnGly: 2.372 ± 0.044	0.667GlnHis: 0.667 ± 0.019	1.841GlnIle: 1.841 ± 0.044	1.189GlnLys: 1.189 ± 0.031	2.848GlnLeu: 2.848 ± 0.05	0.89GlnMet: 0.89 ± 0.029	0.896GlnAsn: 0.896 ± 0.024	1.77GlnPro: 1.77 ± 0.036	1.283GlnGln: 1.283 ± 0.031	2.464GlnArg: 2.464 ± 0.042	1.691GlnSer: 1.691 ± 0.034	1.695GlnThr: 1.695 ± 0.037	2.386GlnVal: 2.386 ± 0.064	0.411GlnTrp: 0.411 ± 0.016	0.696GlnTyr: 0.696 ± 0.022	0.0GlnXaa: 0.0 ± 0.0
Arg	8.267ArgAla: 8.267 ± 0.097	0.517ArgCys: 0.517 ± 0.019	3.921ArgAsp: 3.921 ± 0.048	3.913ArgGlu: 3.913 ± 0.061	2.725ArgPhe: 2.725 ± 0.044	5.019ArgGly: 5.019 ± 0.071	1.604ArgHis: 1.604 ± 0.038	3.722ArgIle: 3.722 ± 0.046	2.525ArgLys: 2.525 ± 0.047	7.175ArgLeu: 7.175 ± 0.092	1.846ArgMet: 1.846 ± 0.04	1.849ArgAsn: 1.849 ± 0.032	3.558ArgPro: 3.558 ± 0.052	2.283ArgGln: 2.283 ± 0.041	5.427ArgArg: 5.427 ± 0.075	3.384ArgSer: 3.384 ± 0.046	3.361ArgThr: 3.361 ± 0.048	4.909ArgVal: 4.909 ± 0.06	0.988ArgTrp: 0.988 ± 0.022	1.772ArgTyr: 1.772 ± 0.037	0.0ArgXaa: 0.0 ± 0.0
Ser	6.093SerAla: 6.093 ± 0.079	0.388SerCys: 0.388 ± 0.017	2.732SerAsp: 2.732 ± 0.044	2.504SerGlu: 2.504 ± 0.048	2.211SerPhe: 2.211 ± 0.035	5.054SerGly: 5.054 ± 0.083	1.016SerHis: 1.016 ± 0.023	2.713SerIle: 2.713 ± 0.042	1.771SerLys: 1.771 ± 0.035	5.073SerLeu: 5.073 ± 0.065	1.282SerMet: 1.282 ± 0.025	1.451SerAsn: 1.451 ± 0.035	2.784SerPro: 2.784 ± 0.045	1.561SerGln: 1.561 ± 0.036	3.274SerArg: 3.274 ± 0.045	2.886SerSer: 2.886 ± 0.061	2.85SerThr: 2.85 ± 0.087	3.846SerVal: 3.846 ± 0.063	0.678SerTrp: 0.678 ± 0.021	1.328SerTyr: 1.328 ± 0.032	0.0SerXaa: 0.0 ± 0.0
Thr	6.653ThrAla: 6.653 ± 0.094	0.432ThrCys: 0.432 ± 0.015	2.74ThrAsp: 2.74 ± 0.047	2.481ThrGlu: 2.481 ± 0.045	2.109ThrPhe: 2.109 ± 0.038	4.825ThrGly: 4.825 ± 0.083	1.049ThrHis: 1.049 ± 0.025	3.04ThrIle: 3.04 ± 0.045	1.76ThrLys: 1.76 ± 0.036	5.859ThrLeu: 5.859 ± 0.063	1.21ThrMet: 1.21 ± 0.03	1.469ThrAsn: 1.469 ± 0.037	3.556ThrPro: 3.556 ± 0.047	1.798ThrGln: 1.798 ± 0.087	3.308ThrArg: 3.308 ± 0.048	2.84ThrSer: 2.84 ± 0.061	3.311ThrThr: 3.311 ± 0.156	4.683ThrVal: 4.683 ± 0.073	0.691ThrTrp: 0.691 ± 0.022	1.236ThrTyr: 1.236 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	9.97ValAla: 9.97 ± 0.093	0.673ValCys: 0.673 ± 0.023	4.324ValAsp: 4.324 ± 0.053	4.267ValGlu: 4.267 ± 0.061	2.762ValPhe: 2.762 ± 0.049	5.885ValGly: 5.885 ± 0.072	1.47ValHis: 1.47 ± 0.034	4.076ValIle: 4.076 ± 0.052	2.852ValLys: 2.852 ± 0.047	7.648ValLeu: 7.648 ± 0.086	1.917ValMet: 1.917 ± 0.037	2.201ValAsn: 2.201 ± 0.048	4.149ValPro: 4.149 ± 0.055	2.136ValGln: 2.136 ± 0.036	5.094ValArg: 5.094 ± 0.061	4.259ValSer: 4.259 ± 0.059	4.831ValThr: 4.831 ± 0.07	6.513ValVal: 6.513 ± 0.076	0.89ValTrp: 0.89 ± 0.027	1.621ValTyr: 1.621 ± 0.033	0.0ValXaa: 0.0 ± 0.0
Trp	1.147TrpAla: 1.147 ± 0.026	0.134TrpCys: 0.134 ± 0.01	0.623TrpAsp: 0.623 ± 0.019	0.497TrpGlu: 0.497 ± 0.021	0.527TrpPhe: 0.527 ± 0.019	0.9TrpGly: 0.9 ± 0.025	0.357TrpHis: 0.357 ± 0.015	0.637TrpIle: 0.637 ± 0.02	0.475TrpLys: 0.475 ± 0.017	1.592TrpLeu: 1.592 ± 0.035	0.356TrpMet: 0.356 ± 0.014	0.414TrpAsn: 0.414 ± 0.018	0.72TrpPro: 0.72 ± 0.021	0.545TrpGln: 0.545 ± 0.02	1.154TrpArg: 1.154 ± 0.027	0.805TrpSer: 0.805 ± 0.021	0.822TrpThr: 0.822 ± 0.023	0.789TrpVal: 0.789 ± 0.021	0.213TrpTrp: 0.213 ± 0.012	0.302TrpTyr: 0.302 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.753TyrAla: 2.753 ± 0.04	0.255TyrCys: 0.255 ± 0.013	1.524TyrAsp: 1.524 ± 0.035	1.236TyrGlu: 1.236 ± 0.032	0.969TyrPhe: 0.969 ± 0.025	2.161TyrGly: 2.161 ± 0.042	0.434TyrHis: 0.434 ± 0.017	0.965TyrIle: 0.965 ± 0.026	0.773TyrLys: 0.773 ± 0.023	2.326TyrLeu: 2.326 ± 0.043	0.446TyrMet: 0.446 ± 0.018	0.659TyrAsn: 0.659 ± 0.026	1.264TyrPro: 1.264 ± 0.027	0.713TyrGln: 0.713 ± 0.024	1.809TyrArg: 1.809 ± 0.035	1.144TyrSer: 1.144 ± 0.03	1.263TyrThr: 1.263 ± 0.032	1.79TyrVal: 1.79 ± 0.035	0.351TyrTrp: 0.351 ± 0.015	0.655TyrTyr: 0.655 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 5199 proteins (1630845 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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