Amino acid dipepetide frequency for Changjiang tombus-like virus 14

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.196AlaAla: 6.196 ± 6.217
1.239AlaCys: 1.239 ± 1.243
4.957AlaAsp: 4.957 ± 2.953
0.0AlaGlu: 0.0 ± 0.0
3.717AlaPhe: 3.717 ± 0.312
1.239AlaGly: 1.239 ± 1.243
0.0AlaHis: 0.0 ± 0.0
3.717AlaIle: 3.717 ± 3.73
4.957AlaLys: 4.957 ± 0.932
8.674AlaLeu: 8.674 ± 1.401
2.478AlaMet: 2.478 ± 2.487
2.478AlaAsn: 2.478 ± 2.487
7.435AlaPro: 7.435 ± 1.397
0.0AlaGln: 0.0 ± 0.0
9.913AlaArg: 9.913 ± 2.179
4.957AlaSer: 4.957 ± 0.932
9.913AlaThr: 9.913 ± 7.927
8.674AlaVal: 8.674 ± 2.641
0.0AlaTrp: 0.0 ± 0.0
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
3.717CysAla: 3.717 ± 3.73
0.0CysCys: 0.0 ± 0.0
2.478CysAsp: 2.478 ± 0.466
2.478CysGlu: 2.478 ± 1.555
1.239CysPhe: 1.239 ± 0.778
2.478CysGly: 2.478 ± 0.466
0.0CysHis: 0.0 ± 0.0
0.0CysIle: 0.0 ± 0.0
0.0CysLys: 0.0 ± 0.0
1.239CysLeu: 1.239 ± 0.778
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
0.0CysPro: 0.0 ± 0.0
1.239CysGln: 1.239 ± 0.778
2.478CysArg: 2.478 ± 1.555
3.717CysSer: 3.717 ± 1.709
0.0CysThr: 0.0 ± 0.0
4.957CysVal: 4.957 ± 1.089
0.0CysTrp: 0.0 ± 0.0
2.478CysTyr: 2.478 ± 1.555
0.0CysXaa: 0.0 ± 0.0
Asp
6.196AspAla: 6.196 ± 0.154
1.239AspCys: 1.239 ± 0.778
2.478AspAsp: 2.478 ± 0.466
3.717AspGlu: 3.717 ± 2.333
1.239AspPhe: 1.239 ± 0.778
9.913AspGly: 9.913 ± 6.221
0.0AspHis: 0.0 ± 0.0
1.239AspIle: 1.239 ± 0.778
2.478AspLys: 2.478 ± 2.487
6.196AspLeu: 6.196 ± 0.154
1.239AspMet: 1.239 ± 0.778
1.239AspAsn: 1.239 ± 0.778
3.717AspPro: 3.717 ± 0.312
1.239AspGln: 1.239 ± 0.778
3.717AspArg: 3.717 ± 1.709
2.478AspSer: 2.478 ± 0.466
1.239AspThr: 1.239 ± 0.778
0.0AspVal: 0.0 ± 0.0
1.239AspTrp: 1.239 ± 1.243
3.717AspTyr: 3.717 ± 1.709
0.0AspXaa: 0.0 ± 0.0
Glu
3.717GluAla: 3.717 ± 0.312
2.478GluCys: 2.478 ± 0.466
1.239GluAsp: 1.239 ± 0.778
3.717GluGlu: 3.717 ± 2.333
4.957GluPhe: 4.957 ± 3.111
0.0GluGly: 0.0 ± 0.0
4.957GluHis: 4.957 ± 3.111
2.478GluIle: 2.478 ± 1.555
2.478GluLys: 2.478 ± 1.555
3.717GluLeu: 3.717 ± 0.312
0.0GluMet: 0.0 ± 0.0
1.239GluAsn: 1.239 ± 0.778
0.0GluPro: 0.0 ± 0.0
4.957GluGln: 4.957 ± 3.111
4.957GluArg: 4.957 ± 3.111
4.957GluSer: 4.957 ± 1.089
2.478GluThr: 2.478 ± 0.466
2.478GluVal: 2.478 ± 2.487
2.478GluTrp: 2.478 ± 0.466
2.478GluTyr: 2.478 ± 1.555
0.0GluXaa: 0.0 ± 0.0
Phe
0.0PheAla: 0.0 ± 0.0
3.717PheCys: 3.717 ± 0.312
3.717PheAsp: 3.717 ± 2.333
1.239PheGlu: 1.239 ± 0.778
1.239PhePhe: 1.239 ± 1.243
3.717PheGly: 3.717 ± 0.312
1.239PheHis: 1.239 ± 0.778
2.478PheIle: 2.478 ± 0.466
1.239PheLys: 1.239 ± 0.778
2.478PheLeu: 2.478 ± 0.466
1.239PheMet: 1.239 ± 0.778
3.717PheAsn: 3.717 ± 2.333
2.478PhePro: 2.478 ± 0.466
0.0PheGln: 0.0 ± 0.0
2.478PheArg: 2.478 ± 0.466
0.0PheSer: 0.0 ± 0.0
3.717PheThr: 3.717 ± 0.312
2.478PheVal: 2.478 ± 1.555
0.0PheTrp: 0.0 ± 0.0
3.717PheTyr: 3.717 ± 2.333
0.0PheXaa: 0.0 ± 0.0
Gly
7.435GlyAla: 7.435 ± 7.461
1.239GlyCys: 1.239 ± 0.778
7.435GlyAsp: 7.435 ± 0.624
4.957GlyGlu: 4.957 ± 3.111
3.717GlyPhe: 3.717 ± 0.312
3.717GlyGly: 3.717 ± 0.312
0.0GlyHis: 0.0 ± 0.0
7.435GlyIle: 7.435 ± 1.397
7.435GlyLys: 7.435 ± 1.397
9.913GlyLeu: 9.913 ± 2.179
2.478GlyMet: 2.478 ± 2.487
2.478GlyAsn: 2.478 ± 0.466
1.239GlyPro: 1.239 ± 0.778
0.0GlyGln: 0.0 ± 0.0
6.196GlyArg: 6.196 ± 3.888
2.478GlySer: 2.478 ± 0.466
6.196GlyThr: 6.196 ± 2.175
3.717GlyVal: 3.717 ± 2.333
0.0GlyTrp: 0.0 ± 0.0
1.239GlyTyr: 1.239 ± 1.243
0.0GlyXaa: 0.0 ± 0.0
His
1.239HisAla: 1.239 ± 0.778
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
0.0HisGly: 0.0 ± 0.0
0.0HisHis: 0.0 ± 0.0
2.478HisIle: 2.478 ± 1.555
0.0HisLys: 0.0 ± 0.0
2.478HisLeu: 2.478 ± 1.555
0.0HisMet: 0.0 ± 0.0
1.239HisAsn: 1.239 ± 0.778
0.0HisPro: 0.0 ± 0.0
0.0HisGln: 0.0 ± 0.0
2.478HisArg: 2.478 ± 1.555
2.478HisSer: 2.478 ± 1.555
0.0HisThr: 0.0 ± 0.0
2.478HisVal: 2.478 ± 1.555
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
2.478IleAla: 2.478 ± 1.555
1.239IleCys: 1.239 ± 0.778
1.239IleAsp: 1.239 ± 0.778
2.478IleGlu: 2.478 ± 1.555
1.239IlePhe: 1.239 ± 0.778
4.957IleGly: 4.957 ± 2.953
0.0IleHis: 0.0 ± 0.0
0.0IleIle: 0.0 ± 0.0
2.478IleLys: 2.478 ± 1.555
0.0IleLeu: 0.0 ± 0.0
2.478IleMet: 2.478 ± 0.466
3.717IleAsn: 3.717 ± 1.709
1.239IlePro: 1.239 ± 1.243
2.478IleGln: 2.478 ± 1.555
1.239IleArg: 1.239 ± 0.778
3.717IleSer: 3.717 ± 0.312
4.957IleThr: 4.957 ± 1.089
4.957IleVal: 4.957 ± 0.932
1.239IleTrp: 1.239 ± 1.243
1.239IleTyr: 1.239 ± 1.243
0.0IleXaa: 0.0 ± 0.0
Lys
3.717LysAla: 3.717 ± 0.312
1.239LysCys: 1.239 ± 0.778
3.717LysAsp: 3.717 ± 0.312
2.478LysGlu: 2.478 ± 2.487
1.239LysPhe: 1.239 ± 0.778
3.717LysGly: 3.717 ± 2.333
0.0LysHis: 0.0 ± 0.0
1.239LysIle: 1.239 ± 0.778
4.957LysLys: 4.957 ± 4.974
3.717LysLeu: 3.717 ± 0.312
4.957LysMet: 4.957 ± 0.079
0.0LysAsn: 0.0 ± 0.0
3.717LysPro: 3.717 ± 0.312
1.239LysGln: 1.239 ± 1.243
2.478LysArg: 2.478 ± 1.555
2.478LysSer: 2.478 ± 0.466
4.957LysThr: 4.957 ± 2.953
7.435LysVal: 7.435 ± 0.624
1.239LysTrp: 1.239 ± 0.778
2.478LysTyr: 2.478 ± 0.466
0.0LysXaa: 0.0 ± 0.0
Leu
3.717LeuAla: 3.717 ± 2.333
2.478LeuCys: 2.478 ± 0.466
7.435LeuAsp: 7.435 ± 0.624
7.435LeuGlu: 7.435 ± 0.624
3.717LeuPhe: 3.717 ± 2.333
6.196LeuGly: 6.196 ± 0.154
0.0LeuHis: 0.0 ± 0.0
6.196LeuIle: 6.196 ± 1.867
3.717LeuLys: 3.717 ± 1.709
4.957LeuLeu: 4.957 ± 1.089
2.478LeuMet: 2.478 ± 0.466
3.717LeuAsn: 3.717 ± 1.709
3.717LeuPro: 3.717 ± 0.312
2.478LeuGln: 2.478 ± 0.466
2.478LeuArg: 2.478 ± 1.555
3.717LeuSer: 3.717 ± 0.312
0.0LeuThr: 0.0 ± 0.0
8.674LeuVal: 8.674 ± 3.422
0.0LeuTrp: 0.0 ± 0.0
3.717LeuTyr: 3.717 ± 0.312
0.0LeuXaa: 0.0 ± 0.0
Met
2.478MetAla: 2.478 ± 2.487
1.239MetCys: 1.239 ± 0.778
1.239MetAsp: 1.239 ± 0.778
2.478MetGlu: 2.478 ± 0.466
0.0MetPhe: 0.0 ± 0.0
1.239MetGly: 1.239 ± 1.243
0.0MetHis: 0.0 ± 0.0
1.239MetIle: 1.239 ± 1.243
1.239MetLys: 1.239 ± 0.778
0.0MetLeu: 0.0 ± 0.0
0.0MetMet: 0.0 ± 0.0
1.239MetAsn: 1.239 ± 0.778
2.478MetPro: 2.478 ± 1.555
1.239MetGln: 1.239 ± 1.243
1.239MetArg: 1.239 ± 0.778
1.239MetSer: 1.239 ± 0.778
2.478MetThr: 2.478 ± 0.466
1.239MetVal: 1.239 ± 0.778
1.239MetTrp: 1.239 ± 0.778
2.478MetTyr: 2.478 ± 2.487
0.0MetXaa: 0.0 ± 0.0
Asn
3.717AsnAla: 3.717 ± 3.73
1.239AsnCys: 1.239 ± 0.778
4.957AsnAsp: 4.957 ± 0.932
1.239AsnGlu: 1.239 ± 0.778
2.478AsnPhe: 2.478 ± 1.555
2.478AsnGly: 2.478 ± 0.466
1.239AsnHis: 1.239 ± 0.778
1.239AsnIle: 1.239 ± 1.243
1.239AsnLys: 1.239 ± 0.778
1.239AsnLeu: 1.239 ± 1.243
0.0AsnMet: 0.0 ± 0.0
2.478AsnAsn: 2.478 ± 0.466
2.478AsnPro: 2.478 ± 0.466
0.0AsnGln: 0.0 ± 0.0
2.478AsnArg: 2.478 ± 0.466
1.239AsnSer: 1.239 ± 0.778
6.196AsnThr: 6.196 ± 4.196
6.196AsnVal: 6.196 ± 2.175
0.0AsnTrp: 0.0 ± 0.0
2.478AsnTyr: 2.478 ± 2.487
0.0AsnXaa: 0.0 ± 0.0
Pro
3.717ProAla: 3.717 ± 0.312
1.239ProCys: 1.239 ± 1.243
1.239ProAsp: 1.239 ± 0.778
0.0ProGlu: 0.0 ± 0.0
1.239ProPhe: 1.239 ± 1.243
6.196ProGly: 6.196 ± 4.196
0.0ProHis: 0.0 ± 0.0
4.957ProIle: 4.957 ± 3.111
6.196ProLys: 6.196 ± 3.888
2.478ProLeu: 2.478 ± 0.466
0.0ProMet: 0.0 ± 0.0
4.957ProAsn: 4.957 ± 4.974
1.239ProPro: 1.239 ± 0.778
2.478ProGln: 2.478 ± 1.555
6.196ProArg: 6.196 ± 3.888
2.478ProSer: 2.478 ± 2.487
1.239ProThr: 1.239 ± 0.778
3.717ProVal: 3.717 ± 0.312
0.0ProTrp: 0.0 ± 0.0
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
4.957GlnAla: 4.957 ± 2.953
1.239GlnCys: 1.239 ± 0.778
1.239GlnAsp: 1.239 ± 0.778
0.0GlnGlu: 0.0 ± 0.0
1.239GlnPhe: 1.239 ± 1.243
2.478GlnGly: 2.478 ± 2.487
2.478GlnHis: 2.478 ± 1.555
2.478GlnIle: 2.478 ± 1.555
1.239GlnLys: 1.239 ± 0.778
7.435GlnLeu: 7.435 ± 2.645
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
1.239GlnPro: 1.239 ± 0.778
1.239GlnGln: 1.239 ± 0.778
1.239GlnArg: 1.239 ± 1.243
0.0GlnSer: 0.0 ± 0.0
0.0GlnThr: 0.0 ± 0.0
1.239GlnVal: 1.239 ± 0.778
0.0GlnTrp: 0.0 ± 0.0
2.478GlnTyr: 2.478 ± 0.466
0.0GlnXaa: 0.0 ± 0.0
Arg
7.435ArgAla: 7.435 ± 0.624
3.717ArgCys: 3.717 ± 0.312
2.478ArgAsp: 2.478 ± 0.466
1.239ArgGlu: 1.239 ± 0.778
2.478ArgPhe: 2.478 ± 0.466
9.913ArgGly: 9.913 ± 4.2
1.239ArgHis: 1.239 ± 0.778
0.0ArgIle: 0.0 ± 0.0
3.717ArgLys: 3.717 ± 0.312
4.957ArgLeu: 4.957 ± 3.111
2.478ArgMet: 2.478 ± 1.555
1.239ArgAsn: 1.239 ± 0.778
4.957ArgPro: 4.957 ± 0.932
2.478ArgGln: 2.478 ± 1.555
1.239ArgArg: 1.239 ± 0.778
4.957ArgSer: 4.957 ± 1.089
1.239ArgThr: 1.239 ± 0.778
1.239ArgVal: 1.239 ± 0.778
1.239ArgTrp: 1.239 ± 1.243
4.957ArgTyr: 4.957 ± 1.089
0.0ArgXaa: 0.0 ± 0.0
Ser
6.196SerAla: 6.196 ± 2.175
2.478SerCys: 2.478 ± 0.466
2.478SerAsp: 2.478 ± 0.466
7.435SerGlu: 7.435 ± 0.624
2.478SerPhe: 2.478 ± 1.555
4.957SerGly: 4.957 ± 1.089
0.0SerHis: 0.0 ± 0.0
0.0SerIle: 0.0 ± 0.0
4.957SerLys: 4.957 ± 1.089
4.957SerLeu: 4.957 ± 0.932
0.0SerMet: 0.0 ± 0.0
1.239SerAsn: 1.239 ± 0.778
6.196SerPro: 6.196 ± 0.154
2.478SerGln: 2.478 ± 2.487
2.478SerArg: 2.478 ± 1.555
1.239SerSer: 1.239 ± 1.243
0.0SerThr: 0.0 ± 0.0
6.196SerVal: 6.196 ± 4.196
1.239SerTrp: 1.239 ± 0.778
1.239SerTyr: 1.239 ± 0.778
0.0SerXaa: 0.0 ± 0.0
Thr
4.957ThrAla: 4.957 ± 2.953
1.239ThrCys: 1.239 ± 1.243
2.478ThrAsp: 2.478 ± 1.555
1.239ThrGlu: 1.239 ± 1.243
1.239ThrPhe: 1.239 ± 1.243
7.435ThrGly: 7.435 ± 3.419
2.478ThrHis: 2.478 ± 1.555
2.478ThrIle: 2.478 ± 0.466
1.239ThrLys: 1.239 ± 1.243
4.957ThrLeu: 4.957 ± 0.932
2.478ThrMet: 2.478 ± 1.555
3.717ThrAsn: 3.717 ± 3.73
2.478ThrPro: 2.478 ± 1.555
1.239ThrGln: 1.239 ± 1.243
1.239ThrArg: 1.239 ± 1.243
3.717ThrSer: 3.717 ± 1.709
4.957ThrThr: 4.957 ± 1.089
4.957ThrVal: 4.957 ± 0.932
0.0ThrTrp: 0.0 ± 0.0
2.478ThrTyr: 2.478 ± 0.466
0.0ThrXaa: 0.0 ± 0.0
Val
4.957ValAla: 4.957 ± 0.932
0.0ValCys: 0.0 ± 0.0
1.239ValAsp: 1.239 ± 0.778
6.196ValGlu: 6.196 ± 3.888
4.957ValPhe: 4.957 ± 3.111
4.957ValGly: 4.957 ± 0.932
1.239ValHis: 1.239 ± 0.778
1.239ValIle: 1.239 ± 1.243
4.957ValLys: 4.957 ± 2.953
4.957ValLeu: 4.957 ± 1.089
1.239ValMet: 1.239 ± 1.243
3.717ValAsn: 3.717 ± 1.709
1.239ValPro: 1.239 ± 1.243
3.717ValGln: 3.717 ± 0.312
4.957ValArg: 4.957 ± 2.953
7.435ValSer: 7.435 ± 0.624
3.717ValThr: 3.717 ± 1.709
3.717ValVal: 3.717 ± 1.709
6.196ValTrp: 6.196 ± 3.888
4.957ValTyr: 4.957 ± 1.089
0.0ValXaa: 0.0 ± 0.0
Trp
1.239TrpAla: 1.239 ± 1.243
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
3.717TrpGlu: 3.717 ± 2.333
1.239TrpPhe: 1.239 ± 0.778
1.239TrpGly: 1.239 ± 0.778
0.0TrpHis: 0.0 ± 0.0
0.0TrpIle: 0.0 ± 0.0
0.0TrpLys: 0.0 ± 0.0
0.0TrpLeu: 0.0 ± 0.0
0.0TrpMet: 0.0 ± 0.0
2.478TrpAsn: 2.478 ± 0.466
0.0TrpPro: 0.0 ± 0.0
1.239TrpGln: 1.239 ± 0.778
1.239TrpArg: 1.239 ± 1.243
3.717TrpSer: 3.717 ± 0.312
0.0TrpThr: 0.0 ± 0.0
0.0TrpVal: 0.0 ± 0.0
2.478TrpTrp: 2.478 ± 2.487
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.478TyrAla: 2.478 ± 2.487
1.239TyrCys: 1.239 ± 0.778
2.478TyrAsp: 2.478 ± 1.555
3.717TyrGlu: 3.717 ± 2.333
1.239TyrPhe: 1.239 ± 1.243
2.478TyrGly: 2.478 ± 0.466
0.0TyrHis: 0.0 ± 0.0
2.478TyrIle: 2.478 ± 0.466
3.717TyrLys: 3.717 ± 0.312
2.478TyrLeu: 2.478 ± 0.466
1.239TyrMet: 1.239 ± 0.778
3.717TyrAsn: 3.717 ± 1.709
3.717TyrPro: 3.717 ± 0.312
2.478TyrGln: 2.478 ± 2.487
2.478TyrArg: 2.478 ± 1.555
1.239TyrSer: 1.239 ± 1.243
3.717TyrThr: 3.717 ± 0.312
1.239TyrVal: 1.239 ± 0.778
0.0TyrTrp: 0.0 ± 0.0
1.239TyrTyr: 1.239 ± 1.243
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (808 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski