Amino acid dipepetide frequency for Raptor adenovirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.534AlaAla: 4.534 ± 1.104
0.98AlaCys: 0.98 ± 0.481
3.186AlaAsp: 3.186 ± 0.547
3.553AlaGlu: 3.553 ± 0.625
2.328AlaPhe: 2.328 ± 0.466
3.431AlaGly: 3.431 ± 0.907
1.348AlaHis: 1.348 ± 0.338
4.534AlaIle: 4.534 ± 0.605
2.206AlaLys: 2.206 ± 0.556
4.656AlaLeu: 4.656 ± 0.832
1.47AlaMet: 1.47 ± 0.511
2.451AlaAsn: 2.451 ± 0.714
3.553AlaPro: 3.553 ± 0.65
1.838AlaGln: 1.838 ± 0.488
2.573AlaArg: 2.573 ± 0.816
3.676AlaSer: 3.676 ± 0.911
2.941AlaThr: 2.941 ± 0.614
5.514AlaVal: 5.514 ± 1.429
0.735AlaTrp: 0.735 ± 0.215
2.451AlaTyr: 2.451 ± 0.546
0.0AlaXaa: 0.0 ± 0.0
Cys
0.858CysAla: 0.858 ± 0.29
0.613CysCys: 0.613 ± 0.35
0.735CysAsp: 0.735 ± 0.242
0.735CysGlu: 0.735 ± 0.3
1.103CysPhe: 1.103 ± 0.357
0.858CysGly: 0.858 ± 0.284
0.368CysHis: 0.368 ± 0.191
0.858CysIle: 0.858 ± 0.369
1.47CysLys: 1.47 ± 0.48
0.98CysLeu: 0.98 ± 0.441
0.858CysMet: 0.858 ± 0.234
1.348CysAsn: 1.348 ± 0.447
0.49CysPro: 0.49 ± 0.203
0.735CysGln: 0.735 ± 0.265
0.49CysArg: 0.49 ± 0.21
1.838CysSer: 1.838 ± 0.379
1.348CysThr: 1.348 ± 0.356
1.225CysVal: 1.225 ± 0.355
0.245CysTrp: 0.245 ± 0.188
0.735CysTyr: 0.735 ± 0.35
0.0CysXaa: 0.0 ± 0.0
Asp
2.328AspAla: 2.328 ± 0.639
1.103AspCys: 1.103 ± 0.299
2.328AspAsp: 2.328 ± 0.608
3.431AspGlu: 3.431 ± 0.679
3.186AspPhe: 3.186 ± 0.575
2.941AspGly: 2.941 ± 0.948
1.103AspHis: 1.103 ± 0.447
4.534AspIle: 4.534 ± 0.702
1.838AspLys: 1.838 ± 0.321
4.534AspLeu: 4.534 ± 0.911
0.49AspMet: 0.49 ± 0.217
2.573AspAsn: 2.573 ± 0.517
2.573AspPro: 2.573 ± 0.555
1.593AspGln: 1.593 ± 0.454
1.961AspArg: 1.961 ± 0.468
3.799AspSer: 3.799 ± 0.614
2.941AspThr: 2.941 ± 0.476
3.308AspVal: 3.308 ± 0.625
0.123AspTrp: 0.123 ± 0.106
2.818AspTyr: 2.818 ± 0.752
0.0AspXaa: 0.0 ± 0.0
Glu
3.431GluAla: 3.431 ± 0.797
1.348GluCys: 1.348 ± 0.386
2.451GluAsp: 2.451 ± 0.682
6.127GluGlu: 6.127 ± 1.361
2.451GluPhe: 2.451 ± 0.498
3.186GluGly: 3.186 ± 0.644
1.225GluHis: 1.225 ± 0.426
4.289GluIle: 4.289 ± 0.853
3.553GluLys: 3.553 ± 0.942
5.391GluLeu: 5.391 ± 0.63
1.47GluMet: 1.47 ± 0.341
3.799GluAsn: 3.799 ± 0.685
1.348GluPro: 1.348 ± 0.399
1.348GluGln: 1.348 ± 0.35
2.941GluArg: 2.941 ± 0.861
3.553GluSer: 3.553 ± 0.734
3.308GluThr: 3.308 ± 0.718
1.838GluVal: 1.838 ± 0.538
0.98GluTrp: 0.98 ± 0.276
2.451GluTyr: 2.451 ± 0.387
0.0GluXaa: 0.0 ± 0.0
Phe
2.818PheAla: 2.818 ± 0.618
0.613PheCys: 0.613 ± 0.348
2.818PheAsp: 2.818 ± 0.737
2.206PheGlu: 2.206 ± 0.493
2.696PhePhe: 2.696 ± 0.586
1.838PheGly: 1.838 ± 0.396
1.348PheHis: 1.348 ± 0.558
3.308PheIle: 3.308 ± 0.622
2.941PheLys: 2.941 ± 0.657
5.391PheLeu: 5.391 ± 0.974
0.858PheMet: 0.858 ± 0.256
3.308PheAsn: 3.308 ± 0.533
2.573PhePro: 2.573 ± 0.496
1.838PheGln: 1.838 ± 0.349
2.451PheArg: 2.451 ± 0.558
4.166PheSer: 4.166 ± 0.751
2.206PheThr: 2.206 ± 0.513
3.186PheVal: 3.186 ± 0.86
0.245PheTrp: 0.245 ± 0.173
1.961PheTyr: 1.961 ± 0.587
0.0PheXaa: 0.0 ± 0.0
Gly
3.308GlyAla: 3.308 ± 0.844
0.613GlyCys: 0.613 ± 0.25
2.328GlyAsp: 2.328 ± 0.472
3.553GlyGlu: 3.553 ± 0.897
1.348GlyPhe: 1.348 ± 0.364
3.553GlyGly: 3.553 ± 0.868
0.98GlyHis: 0.98 ± 0.363
2.818GlyIle: 2.818 ± 0.512
2.696GlyLys: 2.696 ± 0.543
4.534GlyLeu: 4.534 ± 1.053
1.103GlyMet: 1.103 ± 0.381
3.553GlyAsn: 3.553 ± 0.877
2.083GlyPro: 2.083 ± 0.605
2.451GlyGln: 2.451 ± 0.509
3.308GlyArg: 3.308 ± 0.651
3.431GlySer: 3.431 ± 1.06
4.779GlyThr: 4.779 ± 1.089
2.696GlyVal: 2.696 ± 0.824
0.858GlyTrp: 0.858 ± 0.296
1.348GlyTyr: 1.348 ± 0.5
0.0GlyXaa: 0.0 ± 0.0
His
0.613HisAla: 0.613 ± 0.179
0.245HisCys: 0.245 ± 0.214
0.49HisAsp: 0.49 ± 0.229
0.98HisGlu: 0.98 ± 0.377
1.715HisPhe: 1.715 ± 0.536
0.98HisGly: 0.98 ± 0.353
0.613HisHis: 0.613 ± 0.256
1.225HisIle: 1.225 ± 0.285
0.858HisLys: 0.858 ± 0.292
1.47HisLeu: 1.47 ± 0.468
0.368HisMet: 0.368 ± 0.197
1.103HisAsn: 1.103 ± 0.364
0.98HisPro: 0.98 ± 0.25
0.49HisGln: 0.49 ± 0.281
1.103HisArg: 1.103 ± 0.328
1.715HisSer: 1.715 ± 0.284
0.858HisThr: 0.858 ± 0.291
0.98HisVal: 0.98 ± 0.405
0.49HisTrp: 0.49 ± 0.27
0.735HisTyr: 0.735 ± 0.265
0.0HisXaa: 0.0 ± 0.0
Ile
3.063IleAla: 3.063 ± 0.747
0.98IleCys: 0.98 ± 0.315
2.206IleAsp: 2.206 ± 0.704
2.696IleGlu: 2.696 ± 0.461
2.696IlePhe: 2.696 ± 0.625
3.308IleGly: 3.308 ± 0.923
1.225IleHis: 1.225 ± 0.46
2.573IleIle: 2.573 ± 0.703
3.676IleLys: 3.676 ± 1.019
7.965IleLeu: 7.965 ± 1.189
0.735IleMet: 0.735 ± 0.23
3.676IleAsn: 3.676 ± 0.631
4.534IlePro: 4.534 ± 0.645
3.308IleGln: 3.308 ± 0.626
2.696IleArg: 2.696 ± 0.531
4.779IleSer: 4.779 ± 0.814
6.127IleThr: 6.127 ± 0.746
3.553IleVal: 3.553 ± 0.63
0.735IleTrp: 0.735 ± 0.231
2.696IleTyr: 2.696 ± 0.539
0.0IleXaa: 0.0 ± 0.0
Lys
2.818LysAla: 2.818 ± 0.619
0.735LysCys: 0.735 ± 0.239
2.941LysAsp: 2.941 ± 0.519
3.553LysGlu: 3.553 ± 0.954
3.431LysPhe: 3.431 ± 0.711
2.818LysGly: 2.818 ± 0.588
1.225LysHis: 1.225 ± 0.393
2.941LysIle: 2.941 ± 0.733
3.553LysLys: 3.553 ± 0.961
6.249LysLeu: 6.249 ± 0.969
1.225LysMet: 1.225 ± 0.404
3.308LysAsn: 3.308 ± 0.688
2.451LysPro: 2.451 ± 0.417
2.083LysGln: 2.083 ± 0.655
3.553LysArg: 3.553 ± 0.619
3.186LysSer: 3.186 ± 0.776
2.573LysThr: 2.573 ± 0.477
1.961LysVal: 1.961 ± 0.426
0.49LysTrp: 0.49 ± 0.26
2.328LysTyr: 2.328 ± 0.493
0.0LysXaa: 0.0 ± 0.0
Leu
5.882LeuAla: 5.882 ± 0.795
2.818LeuCys: 2.818 ± 0.703
5.269LeuAsp: 5.269 ± 0.776
4.289LeuGlu: 4.289 ± 0.851
2.818LeuPhe: 2.818 ± 0.514
3.308LeuGly: 3.308 ± 0.659
1.961LeuHis: 1.961 ± 0.514
5.514LeuIle: 5.514 ± 0.722
6.127LeuLys: 6.127 ± 0.847
8.577LeuLeu: 8.577 ± 1.234
1.715LeuMet: 1.715 ± 0.379
6.617LeuAsn: 6.617 ± 0.989
6.494LeuPro: 6.494 ± 1.015
6.004LeuGln: 6.004 ± 0.9
5.024LeuArg: 5.024 ± 1.122
5.882LeuSer: 5.882 ± 0.807
7.107LeuThr: 7.107 ± 1.578
4.779LeuVal: 4.779 ± 0.831
0.858LeuTrp: 0.858 ± 0.256
3.553LeuTyr: 3.553 ± 0.73
0.0LeuXaa: 0.0 ± 0.0
Met
0.858MetAla: 0.858 ± 0.325
0.368MetCys: 0.368 ± 0.204
1.103MetAsp: 1.103 ± 0.462
0.98MetGlu: 0.98 ± 0.329
1.103MetPhe: 1.103 ± 0.362
1.348MetGly: 1.348 ± 0.483
0.49MetHis: 0.49 ± 0.24
1.103MetIle: 1.103 ± 0.351
0.98MetLys: 0.98 ± 0.315
1.838MetLeu: 1.838 ± 0.394
0.245MetMet: 0.245 ± 0.176
1.715MetAsn: 1.715 ± 0.448
1.348MetPro: 1.348 ± 0.319
2.083MetGln: 2.083 ± 0.559
1.103MetArg: 1.103 ± 0.523
1.348MetSer: 1.348 ± 0.313
1.47MetThr: 1.47 ± 0.389
0.735MetVal: 0.735 ± 0.2
0.123MetTrp: 0.123 ± 0.094
0.858MetTyr: 0.858 ± 0.3
0.0MetXaa: 0.0 ± 0.0
Asn
2.818AsnAla: 2.818 ± 0.477
1.348AsnCys: 1.348 ± 0.354
2.573AsnAsp: 2.573 ± 0.603
2.941AsnGlu: 2.941 ± 0.655
4.044AsnPhe: 4.044 ± 0.707
2.206AsnGly: 2.206 ± 0.7
0.735AsnHis: 0.735 ± 0.246
4.901AsnIle: 4.901 ± 1.034
2.573AsnLys: 2.573 ± 0.403
7.23AsnLeu: 7.23 ± 0.94
1.593AsnMet: 1.593 ± 0.375
3.308AsnAsn: 3.308 ± 0.91
3.063AsnPro: 3.063 ± 0.674
3.553AsnGln: 3.553 ± 0.93
2.328AsnArg: 2.328 ± 0.435
4.289AsnSer: 4.289 ± 0.555
4.411AsnThr: 4.411 ± 1.208
4.656AsnVal: 4.656 ± 0.719
0.735AsnTrp: 0.735 ± 0.36
3.308AsnTyr: 3.308 ± 0.619
0.0AsnXaa: 0.0 ± 0.0
Pro
5.391ProAla: 5.391 ± 1.389
0.245ProCys: 0.245 ± 0.15
3.308ProAsp: 3.308 ± 0.665
4.044ProGlu: 4.044 ± 0.762
3.921ProPhe: 3.921 ± 0.46
2.328ProGly: 2.328 ± 0.57
0.368ProHis: 0.368 ± 0.18
2.573ProIle: 2.573 ± 0.482
1.838ProLys: 1.838 ± 0.623
4.166ProLeu: 4.166 ± 0.887
1.715ProMet: 1.715 ± 0.425
2.573ProAsn: 2.573 ± 0.728
4.901ProPro: 4.901 ± 0.809
1.715ProGln: 1.715 ± 0.382
2.696ProArg: 2.696 ± 0.625
4.901ProSer: 4.901 ± 0.761
3.921ProThr: 3.921 ± 0.705
4.534ProVal: 4.534 ± 0.992
0.245ProTrp: 0.245 ± 0.127
1.715ProTyr: 1.715 ± 0.36
0.0ProXaa: 0.0 ± 0.0
Gln
3.676GlnAla: 3.676 ± 0.69
0.49GlnCys: 0.49 ± 0.245
2.206GlnAsp: 2.206 ± 0.404
2.328GlnGlu: 2.328 ± 0.659
1.593GlnPhe: 1.593 ± 0.463
2.573GlnGly: 2.573 ± 0.649
0.735GlnHis: 0.735 ± 0.263
3.186GlnIle: 3.186 ± 0.7
2.573GlnLys: 2.573 ± 0.689
4.901GlnLeu: 4.901 ± 0.746
0.98GlnMet: 0.98 ± 0.493
3.431GlnAsn: 3.431 ± 0.426
2.451GlnPro: 2.451 ± 0.448
2.451GlnGln: 2.451 ± 0.669
2.818GlnArg: 2.818 ± 0.482
2.818GlnSer: 2.818 ± 0.584
2.941GlnThr: 2.941 ± 0.764
2.206GlnVal: 2.206 ± 0.49
0.613GlnTrp: 0.613 ± 0.316
1.348GlnTyr: 1.348 ± 0.381
0.0GlnXaa: 0.0 ± 0.0
Arg
1.838ArgAla: 1.838 ± 0.825
0.613ArgCys: 0.613 ± 0.318
2.818ArgAsp: 2.818 ± 0.588
2.328ArgGlu: 2.328 ± 0.382
2.206ArgPhe: 2.206 ± 0.696
2.451ArgGly: 2.451 ± 0.528
0.368ArgHis: 0.368 ± 0.189
3.308ArgIle: 3.308 ± 0.6
2.818ArgLys: 2.818 ± 0.603
3.921ArgLeu: 3.921 ± 0.701
1.593ArgMet: 1.593 ± 0.382
3.063ArgAsn: 3.063 ± 0.496
2.451ArgPro: 2.451 ± 0.696
3.063ArgGln: 3.063 ± 0.782
5.146ArgArg: 5.146 ± 2.175
3.799ArgSer: 3.799 ± 0.646
2.328ArgThr: 2.328 ± 0.439
3.553ArgVal: 3.553 ± 0.767
0.123ArgTrp: 0.123 ± 0.119
2.573ArgTyr: 2.573 ± 0.541
0.0ArgXaa: 0.0 ± 0.0
Ser
3.553SerAla: 3.553 ± 0.702
1.225SerCys: 1.225 ± 0.332
3.676SerAsp: 3.676 ± 0.703
3.308SerGlu: 3.308 ± 0.488
3.799SerPhe: 3.799 ± 0.424
5.024SerGly: 5.024 ± 0.784
0.613SerHis: 0.613 ± 0.292
5.391SerIle: 5.391 ± 0.727
4.411SerLys: 4.411 ± 0.845
6.372SerLeu: 6.372 ± 0.995
1.348SerMet: 1.348 ± 0.279
4.166SerAsn: 4.166 ± 0.938
4.534SerPro: 4.534 ± 0.518
2.941SerGln: 2.941 ± 0.524
2.206SerArg: 2.206 ± 0.501
5.391SerSer: 5.391 ± 0.657
5.269SerThr: 5.269 ± 1.244
4.044SerVal: 4.044 ± 0.662
0.735SerTrp: 0.735 ± 0.302
2.941SerTyr: 2.941 ± 0.537
0.0SerXaa: 0.0 ± 0.0
Thr
4.656ThrAla: 4.656 ± 0.807
1.103ThrCys: 1.103 ± 0.314
3.186ThrAsp: 3.186 ± 0.562
5.146ThrGlu: 5.146 ± 0.965
2.818ThrPhe: 2.818 ± 0.636
4.044ThrGly: 4.044 ± 0.737
0.98ThrHis: 0.98 ± 0.423
4.411ThrIle: 4.411 ± 0.912
3.186ThrLys: 3.186 ± 0.766
5.637ThrLeu: 5.637 ± 0.904
0.49ThrMet: 0.49 ± 0.204
3.921ThrAsn: 3.921 ± 0.657
3.308ThrPro: 3.308 ± 0.67
3.676ThrGln: 3.676 ± 0.461
2.941ThrArg: 2.941 ± 0.425
4.411ThrSer: 4.411 ± 0.77
4.289ThrThr: 4.289 ± 0.829
3.921ThrVal: 3.921 ± 0.523
0.858ThrTrp: 0.858 ± 0.359
4.044ThrTyr: 4.044 ± 0.681
0.0ThrXaa: 0.0 ± 0.0
Val
2.941ValAla: 2.941 ± 0.831
1.348ValCys: 1.348 ± 0.385
3.553ValAsp: 3.553 ± 0.628
2.941ValGlu: 2.941 ± 0.681
2.573ValPhe: 2.573 ± 0.554
2.328ValGly: 2.328 ± 0.409
0.613ValHis: 0.613 ± 0.245
2.818ValIle: 2.818 ± 0.437
3.799ValLys: 3.799 ± 0.703
5.882ValLeu: 5.882 ± 0.584
1.103ValMet: 1.103 ± 0.373
4.534ValAsn: 4.534 ± 0.638
4.779ValPro: 4.779 ± 1.064
2.818ValGln: 2.818 ± 0.56
3.186ValArg: 3.186 ± 0.737
3.676ValSer: 3.676 ± 0.634
3.921ValThr: 3.921 ± 0.622
5.146ValVal: 5.146 ± 1.063
0.49ValTrp: 0.49 ± 0.233
2.083ValTyr: 2.083 ± 0.507
0.0ValXaa: 0.0 ± 0.0
Trp
0.613TrpAla: 0.613 ± 0.3
0.368TrpCys: 0.368 ± 0.174
0.123TrpAsp: 0.123 ± 0.121
0.368TrpGlu: 0.368 ± 0.157
0.613TrpPhe: 0.613 ± 0.236
0.49TrpGly: 0.49 ± 0.248
0.368TrpHis: 0.368 ± 0.228
1.103TrpIle: 1.103 ± 0.33
0.613TrpLys: 0.613 ± 0.287
1.348TrpLeu: 1.348 ± 0.47
0.245TrpMet: 0.245 ± 0.186
0.49TrpAsn: 0.49 ± 0.255
0.613TrpPro: 0.613 ± 0.276
0.613TrpGln: 0.613 ± 0.289
0.245TrpArg: 0.245 ± 0.19
0.98TrpSer: 0.98 ± 0.364
1.348TrpThr: 1.348 ± 0.428
0.0TrpVal: 0.0 ± 0.0
0.368TrpTrp: 0.368 ± 0.229
0.123TrpTyr: 0.123 ± 0.107
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.083TyrAla: 2.083 ± 0.334
0.735TyrCys: 0.735 ± 0.266
2.206TyrAsp: 2.206 ± 0.767
0.98TyrGlu: 0.98 ± 0.373
2.328TyrPhe: 2.328 ± 0.536
2.328TyrGly: 2.328 ± 0.783
1.348TyrHis: 1.348 ± 0.41
1.838TyrIle: 1.838 ± 0.529
1.715TyrLys: 1.715 ± 0.44
3.553TyrLeu: 3.553 ± 0.77
1.47TyrMet: 1.47 ± 0.331
3.676TyrAsn: 3.676 ± 0.779
2.573TyrPro: 2.573 ± 0.548
1.715TyrGln: 1.715 ± 0.402
1.593TyrArg: 1.593 ± 0.363
3.308TyrSer: 3.308 ± 0.62
2.941TyrThr: 2.941 ± 0.581
2.696TyrVal: 2.696 ± 0.471
0.98TyrTrp: 0.98 ± 0.344
1.593TyrTyr: 1.593 ± 0.378
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 23 proteins (8162 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski