Amino acid dipepetide frequency for Amnibacterium flavum

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.338AlaAla: 19.338 ± 0.213	0.63AlaCys: 0.63 ± 0.032	8.257AlaAsp: 8.257 ± 0.089	7.675AlaGlu: 7.675 ± 0.105	3.776AlaPhe: 3.776 ± 0.064	11.971AlaGly: 11.971 ± 0.135	2.054AlaHis: 2.054 ± 0.051	6.37AlaIle: 6.37 ± 0.097	2.527AlaLys: 2.527 ± 0.053	13.72AlaLeu: 13.72 ± 0.148	2.458AlaMet: 2.458 ± 0.051	2.265AlaAsn: 2.265 ± 0.048	6.283AlaPro: 6.283 ± 0.101	3.326AlaGln: 3.326 ± 0.062	8.714AlaArg: 8.714 ± 0.102	7.902AlaSer: 7.902 ± 0.111	7.334AlaThr: 7.334 ± 0.11	11.517AlaVal: 11.517 ± 0.137	1.613AlaTrp: 1.613 ± 0.042	2.284AlaTyr: 2.284 ± 0.052	0.0AlaXaa: 0.0 ± 0.0
Cys	0.614CysAla: 0.614 ± 0.029	0.042CysCys: 0.042 ± 0.006	0.311CysAsp: 0.311 ± 0.018	0.232CysGlu: 0.232 ± 0.013	0.154CysPhe: 0.154 ± 0.012	0.474CysGly: 0.474 ± 0.025	0.091CysHis: 0.091 ± 0.01	0.18CysIle: 0.18 ± 0.011	0.041CysLys: 0.041 ± 0.006	0.4CysLeu: 0.4 ± 0.02	0.069CysMet: 0.069 ± 0.008	0.102CysAsn: 0.102 ± 0.011	0.249CysPro: 0.249 ± 0.017	0.099CysGln: 0.099 ± 0.01	0.288CysArg: 0.288 ± 0.017	0.325CysSer: 0.325 ± 0.018	0.275CysThr: 0.275 ± 0.015	0.404CysVal: 0.404 ± 0.021	0.118CysTrp: 0.118 ± 0.02	0.098CysTyr: 0.098 ± 0.008	0.0CysXaa: 0.0 ± 0.0
Asp	8.094AspAla: 8.094 ± 0.1	0.246AspCys: 0.246 ± 0.017	4.434AspAsp: 4.434 ± 0.081	4.538AspGlu: 4.538 ± 0.076	1.942AspPhe: 1.942 ± 0.042	6.54AspGly: 6.54 ± 0.206	1.175AspHis: 1.175 ± 0.036	2.653AspIle: 2.653 ± 0.057	0.977AspLys: 0.977 ± 0.032	6.576AspLeu: 6.576 ± 0.09	0.871AspMet: 0.871 ± 0.029	1.018AspAsn: 1.018 ± 0.038	4.319AspPro: 4.319 ± 0.091	1.596AspGln: 1.596 ± 0.037	4.575AspArg: 4.575 ± 0.069	3.466AspSer: 3.466 ± 0.058	3.038AspThr: 3.038 ± 0.061	5.191AspVal: 5.191 ± 0.089	1.041AspTrp: 1.041 ± 0.031	1.391AspTyr: 1.391 ± 0.037	0.0AspXaa: 0.0 ± 0.0
Glu	6.611GluAla: 6.611 ± 0.095	0.196GluCys: 0.196 ± 0.015	2.576GluAsp: 2.576 ± 0.055	2.848GluGlu: 2.848 ± 0.061	1.772GluPhe: 1.772 ± 0.044	4.057GluGly: 4.057 ± 0.07	1.374GluHis: 1.374 ± 0.036	2.964GluIle: 2.964 ± 0.062	1.37GluLys: 1.37 ± 0.038	6.593GluLeu: 6.593 ± 0.097	0.898GluMet: 0.898 ± 0.029	1.231GluAsn: 1.231 ± 0.04	3.024GluPro: 3.024 ± 0.059	2.111GluGln: 2.111 ± 0.053	4.992GluArg: 4.992 ± 0.078	3.386GluSer: 3.386 ± 0.058	3.159GluThr: 3.159 ± 0.061	4.779GluVal: 4.779 ± 0.082	0.884GluTrp: 0.884 ± 0.031	1.156GluTyr: 1.156 ± 0.034	0.0GluXaa: 0.0 ± 0.0
Phe	4.339PheAla: 4.339 ± 0.065	0.179PheCys: 0.179 ± 0.011	2.615PheAsp: 2.615 ± 0.05	1.837PheGlu: 1.837 ± 0.046	1.086PhePhe: 1.086 ± 0.034	3.492PheGly: 3.492 ± 0.057	0.502PheHis: 0.502 ± 0.024	1.31PheIle: 1.31 ± 0.042	0.425PheLys: 0.425 ± 0.019	2.798PheLeu: 2.798 ± 0.06	0.401PheMet: 0.401 ± 0.02	0.697PheAsn: 0.697 ± 0.032	1.385PhePro: 1.385 ± 0.04	0.767PheGln: 0.767 ± 0.028	1.857PheArg: 1.857 ± 0.045	1.861PheSer: 1.861 ± 0.041	2.038PheThr: 2.038 ± 0.046	2.889PheVal: 2.889 ± 0.06	0.5PheTrp: 0.5 ± 0.027	0.709PheTyr: 0.709 ± 0.028	0.0PheXaa: 0.0 ± 0.0
Gly	10.858GlyAla: 10.858 ± 0.115	0.496GlyCys: 0.496 ± 0.022	5.49GlyAsp: 5.49 ± 0.124	4.982GlyGlu: 4.982 ± 0.083	3.308GlyPhe: 3.308 ± 0.052	7.987GlyGly: 7.987 ± 0.119	1.648GlyHis: 1.648 ± 0.049	5.03GlyIle: 5.03 ± 0.089	2.053GlyLys: 2.053 ± 0.055	9.131GlyLeu: 9.131 ± 0.111	1.772GlyMet: 1.772 ± 0.036	1.844GlyAsn: 1.844 ± 0.054	3.964GlyPro: 3.964 ± 0.061	2.415GlyGln: 2.415 ± 0.058	6.435GlyArg: 6.435 ± 0.09	6.348GlySer: 6.348 ± 0.097	5.736GlyThr: 5.736 ± 0.117	8.09GlyVal: 8.09 ± 0.089	1.553GlyTrp: 1.553 ± 0.044	2.4GlyTyr: 2.4 ± 0.048	0.0GlyXaa: 0.0 ± 0.0
His	1.899HisAla: 1.899 ± 0.048	0.097HisCys: 0.097 ± 0.009	1.201HisAsp: 1.201 ± 0.039	1.048HisGlu: 1.048 ± 0.032	0.579HisPhe: 0.579 ± 0.027	1.794HisGly: 1.794 ± 0.045	0.474HisHis: 0.474 ± 0.026	0.715HisIle: 0.715 ± 0.029	0.262HisLys: 0.262 ± 0.016	1.891HisLeu: 1.891 ± 0.046	0.303HisMet: 0.303 ± 0.015	0.33HisAsn: 0.33 ± 0.016	1.357HisPro: 1.357 ± 0.042	0.447HisGln: 0.447 ± 0.02	1.525HisArg: 1.525 ± 0.041	1.012HisSer: 1.012 ± 0.034	0.854HisThr: 0.854 ± 0.031	1.374HisVal: 1.374 ± 0.041	0.289HisTrp: 0.289 ± 0.018	0.421HisTyr: 0.421 ± 0.02	0.0HisXaa: 0.0 ± 0.0
Ile	7.374IleAla: 7.374 ± 0.099	0.243IleCys: 0.243 ± 0.017	3.86IleAsp: 3.86 ± 0.068	3.174IleGlu: 3.174 ± 0.063	1.203IlePhe: 1.203 ± 0.039	5.116IleGly: 5.116 ± 0.08	0.685IleHis: 0.685 ± 0.026	1.855IleIle: 1.855 ± 0.048	0.852IleLys: 0.852 ± 0.03	3.776IleLeu: 3.776 ± 0.068	0.562IleMet: 0.562 ± 0.024	0.982IleAsn: 0.982 ± 0.032	2.631IlePro: 2.631 ± 0.069	1.023IleGln: 1.023 ± 0.032	2.889IleArg: 2.889 ± 0.054	2.814IleSer: 2.814 ± 0.053	2.884IleThr: 2.884 ± 0.056	4.935IleVal: 4.935 ± 0.081	0.572IleTrp: 0.572 ± 0.026	0.808IleTyr: 0.808 ± 0.031	0.0IleXaa: 0.0 ± 0.0
Lys	2.339LysAla: 2.339 ± 0.057	0.06LysCys: 0.06 ± 0.007	0.985LysAsp: 0.985 ± 0.033	0.818LysGlu: 0.818 ± 0.032	0.494LysPhe: 0.494 ± 0.021	1.506LysGly: 1.506 ± 0.047	0.378LysHis: 0.378 ± 0.018	0.898LysIle: 0.898 ± 0.035	0.683LysLys: 0.683 ± 0.031	1.845LysLeu: 1.845 ± 0.045	0.335LysMet: 0.335 ± 0.017	0.483LysAsn: 0.483 ± 0.021	1.154LysPro: 1.154 ± 0.032	0.658LysGln: 0.658 ± 0.028	1.521LysArg: 1.521 ± 0.042	1.201LysSer: 1.201 ± 0.033	1.282LysThr: 1.282 ± 0.037	1.711LysVal: 1.711 ± 0.053	0.254LysTrp: 0.254 ± 0.014	0.458LysTyr: 0.458 ± 0.023	0.0LysXaa: 0.0 ± 0.0
Leu	14.345LeuAla: 14.345 ± 0.156	0.428LeuCys: 0.428 ± 0.022	6.897LeuAsp: 6.897 ± 0.103	5.362LeuGlu: 5.362 ± 0.085	2.961LeuPhe: 2.961 ± 0.066	9.472LeuGly: 9.472 ± 0.107	1.734LeuHis: 1.734 ± 0.044	4.917LeuIle: 4.917 ± 0.079	1.671LeuLys: 1.671 ± 0.05	10.592LeuLeu: 10.592 ± 0.142	1.467LeuMet: 1.467 ± 0.035	1.768LeuAsn: 1.768 ± 0.04	5.605LeuPro: 5.605 ± 0.068	2.445LeuGln: 2.445 ± 0.047	7.138LeuArg: 7.138 ± 0.089	6.258LeuSer: 6.258 ± 0.082	6.322LeuThr: 6.322 ± 0.073	9.354LeuVal: 9.354 ± 0.127	1.141LeuTrp: 1.141 ± 0.033	1.67LeuTyr: 1.67 ± 0.047	0.0LeuXaa: 0.0 ± 0.0
Met	2.005MetAla: 2.005 ± 0.045	0.086MetCys: 0.086 ± 0.009	0.744MetAsp: 0.744 ± 0.028	0.614MetGlu: 0.614 ± 0.027	0.495MetPhe: 0.495 ± 0.022	1.246MetGly: 1.246 ± 0.036	0.316MetHis: 0.316 ± 0.016	0.801MetIle: 0.801 ± 0.03	0.398MetLys: 0.398 ± 0.019	1.662MetLeu: 1.662 ± 0.042	0.274MetMet: 0.274 ± 0.016	0.41MetAsn: 0.41 ± 0.019	1.051MetPro: 1.051 ± 0.03	0.488MetGln: 0.488 ± 0.022	1.287MetArg: 1.287 ± 0.039	1.445MetSer: 1.445 ± 0.039	1.608MetThr: 1.608 ± 0.041	1.275MetVal: 1.275 ± 0.033	0.172MetTrp: 0.172 ± 0.013	0.245MetTyr: 0.245 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	2.451AsnAla: 2.451 ± 0.062	0.118AsnCys: 0.118 ± 0.011	1.184AsnAsp: 1.184 ± 0.041	1.003AsnGlu: 1.003 ± 0.037	0.67AsnPhe: 0.67 ± 0.027	2.104AsnGly: 2.104 ± 0.07	0.316AsnHis: 0.316 ± 0.014	0.856AsnIle: 0.856 ± 0.032	0.399AsnLys: 0.399 ± 0.022	1.906AsnLeu: 1.906 ± 0.046	0.309AsnMet: 0.309 ± 0.018	0.538AsnAsn: 0.538 ± 0.025	1.511AsnPro: 1.511 ± 0.035	0.553AsnGln: 0.553 ± 0.024	1.279AsnArg: 1.279 ± 0.033	1.147AsnSer: 1.147 ± 0.039	1.113AsnThr: 1.113 ± 0.044	1.711AsnVal: 1.711 ± 0.051	0.306AsnTrp: 0.306 ± 0.019	0.517AsnTyr: 0.517 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	7.0ProAla: 7.0 ± 0.099	0.182ProCys: 0.182 ± 0.014	3.944ProAsp: 3.944 ± 0.083	3.648ProGlu: 3.648 ± 0.056	1.763ProPhe: 1.763 ± 0.039	5.062ProGly: 5.062 ± 0.087	0.99ProHis: 0.99 ± 0.033	2.416ProIle: 2.416 ± 0.049	0.995ProLys: 0.995 ± 0.039	4.87ProLeu: 4.87 ± 0.069	0.86ProMet: 0.86 ± 0.033	1.18ProAsn: 1.18 ± 0.095	2.279ProPro: 2.279 ± 0.06	1.378ProGln: 1.378 ± 0.035	3.341ProArg: 3.341 ± 0.06	3.454ProSer: 3.454 ± 0.071	3.626ProThr: 3.626 ± 0.085	4.918ProVal: 4.918 ± 0.082	0.834ProTrp: 0.834 ± 0.029	1.061ProTyr: 1.061 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.157GlnAla: 3.157 ± 0.053	0.098GlnCys: 0.098 ± 0.009	1.135GlnAsp: 1.135 ± 0.038	1.132GlnGlu: 1.132 ± 0.033	0.855GlnPhe: 0.855 ± 0.027	1.941GlnGly: 1.941 ± 0.041	0.547GlnHis: 0.547 ± 0.023	1.475GlnIle: 1.475 ± 0.04	0.603GlnLys: 0.603 ± 0.024	3.12GlnLeu: 3.12 ± 0.057	0.476GlnMet: 0.476 ± 0.022	0.627GlnAsn: 0.627 ± 0.03	1.442GlnPro: 1.442 ± 0.041	1.059GlnGln: 1.059 ± 0.035	2.209GlnArg: 2.209 ± 0.05	1.508GlnSer: 1.508 ± 0.035	1.518GlnThr: 1.518 ± 0.039	2.422GlnVal: 2.422 ± 0.056	0.433GlnTrp: 0.433 ± 0.02	0.597GlnTyr: 0.597 ± 0.024	0.0GlnXaa: 0.0 ± 0.0
Arg	8.283ArgAla: 8.283 ± 0.104	0.259ArgCys: 0.259 ± 0.016	4.325ArgAsp: 4.325 ± 0.064	4.077ArgGlu: 4.077 ± 0.07	2.589ArgPhe: 2.589 ± 0.057	5.578ArgGly: 5.578 ± 0.083	1.458ArgHis: 1.458 ± 0.041	3.766ArgIle: 3.766 ± 0.066	1.306ArgLys: 1.306 ± 0.036	7.248ArgLeu: 7.248 ± 0.095	1.579ArgMet: 1.579 ± 0.04	1.385ArgAsn: 1.385 ± 0.043	3.663ArgPro: 3.663 ± 0.067	1.922ArgGln: 1.922 ± 0.04	6.659ArgArg: 6.659 ± 0.1	4.645ArgSer: 4.645 ± 0.076	4.068ArgThr: 4.068 ± 0.067	5.968ArgVal: 5.968 ± 0.08	1.071ArgTrp: 1.071 ± 0.036	1.584ArgTyr: 1.584 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	8.025SerAla: 8.025 ± 0.097	0.25SerCys: 0.25 ± 0.016	3.823SerAsp: 3.823 ± 0.086	3.123SerGlu: 3.123 ± 0.056	2.001SerPhe: 2.001 ± 0.041	6.392SerGly: 6.392 ± 0.09	1.055SerHis: 1.055 ± 0.034	3.095SerIle: 3.095 ± 0.054	1.169SerLys: 1.169 ± 0.037	5.906SerLeu: 5.906 ± 0.074	1.213SerMet: 1.213 ± 0.033	1.268SerAsn: 1.268 ± 0.041	3.417SerPro: 3.417 ± 0.058	1.456SerGln: 1.456 ± 0.033	4.243SerArg: 4.243 ± 0.071	4.169SerSer: 4.169 ± 0.078	4.214SerThr: 4.214 ± 0.073	5.417SerVal: 5.417 ± 0.074	0.929SerTrp: 0.929 ± 0.029	1.344SerTyr: 1.344 ± 0.037	0.0SerXaa: 0.0 ± 0.0
Thr	7.862ThrAla: 7.862 ± 0.111	0.277ThrCys: 0.277 ± 0.02	3.776ThrAsp: 3.776 ± 0.071	3.094ThrGlu: 3.094 ± 0.058	1.828ThrPhe: 1.828 ± 0.046	6.162ThrGly: 6.162 ± 0.086	1.007ThrHis: 1.007 ± 0.026	2.97ThrIle: 2.97 ± 0.051	1.16ThrLys: 1.16 ± 0.037	5.972ThrLeu: 5.972 ± 0.076	0.924ThrMet: 0.924 ± 0.028	1.169ThrAsn: 1.169 ± 0.037	4.06ThrPro: 4.06 ± 0.099	1.362ThrGln: 1.362 ± 0.032	3.693ThrArg: 3.693 ± 0.059	3.803ThrSer: 3.803 ± 0.086	4.08ThrThr: 4.08 ± 0.095	5.968ThrVal: 5.968 ± 0.094	0.809ThrTrp: 0.809 ± 0.027	1.132ThrTyr: 1.132 ± 0.035	0.0ThrXaa: 0.0 ± 0.0
Val	11.662ValAla: 11.662 ± 0.122	0.452ValCys: 0.452 ± 0.022	6.031ValAsp: 6.031 ± 0.086	5.023ValGlu: 5.023 ± 0.075	2.906ValPhe: 2.906 ± 0.058	7.588ValGly: 7.588 ± 0.102	1.512ValHis: 1.512 ± 0.039	4.465ValIle: 4.465 ± 0.065	1.516ValLys: 1.516 ± 0.041	9.575ValLeu: 9.575 ± 0.128	1.349ValMet: 1.349 ± 0.035	1.785ValAsn: 1.785 ± 0.046	4.639ValPro: 4.639 ± 0.063	2.095ValGln: 2.095 ± 0.048	5.934ValArg: 5.934 ± 0.088	5.501ValSer: 5.501 ± 0.081	5.799ValThr: 5.799 ± 0.087	8.974ValVal: 8.974 ± 0.123	1.111ValTrp: 1.111 ± 0.031	1.564ValTyr: 1.564 ± 0.043	0.0ValXaa: 0.0 ± 0.0
Trp	1.478TrpAla: 1.478 ± 0.037	0.077TrpCys: 0.077 ± 0.009	0.739TrpAsp: 0.739 ± 0.029	0.599TrpGlu: 0.599 ± 0.024	0.57TrpPhe: 0.57 ± 0.022	1.124TrpGly: 1.124 ± 0.04	0.271TrpHis: 0.271 ± 0.016	0.759TrpIle: 0.759 ± 0.025	0.295TrpLys: 0.295 ± 0.016	1.609TrpLeu: 1.609 ± 0.045	0.264TrpMet: 0.264 ± 0.016	0.448TrpAsn: 0.448 ± 0.02	0.683TrpPro: 0.683 ± 0.025	0.564TrpGln: 0.564 ± 0.025	1.161TrpArg: 1.161 ± 0.04	0.957TrpSer: 0.957 ± 0.031	0.973TrpThr: 0.973 ± 0.033	1.036TrpVal: 1.036 ± 0.03	0.328TrpTrp: 0.328 ± 0.018	0.332TrpTyr: 0.332 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.28TyrAla: 2.28 ± 0.05	0.146TyrCys: 0.146 ± 0.013	1.357TyrAsp: 1.357 ± 0.04	1.154TyrGlu: 1.154 ± 0.033	0.732TyrPhe: 0.732 ± 0.026	1.938TyrGly: 1.938 ± 0.043	0.282TyrHis: 0.282 ± 0.02	0.745TyrIle: 0.745 ± 0.027	0.362TyrLys: 0.362 ± 0.02	2.361TyrLeu: 2.361 ± 0.052	0.236TyrMet: 0.236 ± 0.015	0.461TyrAsn: 0.461 ± 0.021	1.084TyrPro: 1.084 ± 0.032	0.589TyrGln: 0.589 ± 0.022	1.693TyrArg: 1.693 ± 0.044	1.306TyrSer: 1.306 ± 0.038	1.187TyrThr: 1.187 ± 0.036	1.552TyrVal: 1.552 ± 0.04	0.309TyrTrp: 0.309 ± 0.018	0.473TyrTyr: 0.473 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 3308 proteins (1063717 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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