Amino acid dipepetide frequency for Pteronotus davyi polyomavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.427AlaAla: 8.427 ± 1.928
0.562AlaCys: 0.562 ± 0.393
2.809AlaAsp: 2.809 ± 1.41
2.247AlaGlu: 2.247 ± 0.889
1.685AlaPhe: 1.685 ± 0.772
3.371AlaGly: 3.371 ± 1.004
0.562AlaHis: 0.562 ± 0.446
2.809AlaIle: 2.809 ± 1.492
1.124AlaLys: 1.124 ± 0.786
10.112AlaLeu: 10.112 ± 2.674
0.0AlaMet: 0.0 ± 0.0
3.371AlaAsn: 3.371 ± 1.745
3.371AlaPro: 3.371 ± 1.684
0.562AlaGln: 0.562 ± 0.544
8.427AlaArg: 8.427 ± 4.039
6.742AlaSer: 6.742 ± 1.264
2.247AlaThr: 2.247 ± 0.982
7.865AlaVal: 7.865 ± 1.65
1.124AlaTrp: 1.124 ± 0.493
2.809AlaTyr: 2.809 ± 0.757
0.0AlaXaa: 0.0 ± 0.0
Cys
2.247CysAla: 2.247 ± 0.986
0.0CysCys: 0.0 ± 0.0
2.247CysAsp: 2.247 ± 1.572
0.562CysGlu: 0.562 ± 0.393
0.562CysPhe: 0.562 ± 0.753
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
1.685CysIle: 1.685 ± 0.832
3.933CysLys: 3.933 ± 1.161
2.247CysLeu: 2.247 ± 1.379
0.562CysMet: 0.562 ± 0.393
0.0CysAsn: 0.0 ± 0.0
1.124CysPro: 1.124 ± 0.493
1.685CysGln: 1.685 ± 1.179
0.562CysArg: 0.562 ± 0.753
1.685CysSer: 1.685 ± 1.39
0.562CysThr: 0.562 ± 0.753
0.562CysVal: 0.562 ± 0.393
0.562CysTrp: 0.562 ± 0.393
2.247CysTyr: 2.247 ± 1.337
0.0CysXaa: 0.0 ± 0.0
Asp
2.247AspAla: 2.247 ± 1.379
0.562AspCys: 0.562 ± 0.393
1.124AspAsp: 1.124 ± 0.786
5.618AspGlu: 5.618 ± 2.646
0.0AspPhe: 0.0 ± 0.0
2.247AspGly: 2.247 ± 1.482
0.0AspHis: 0.0 ± 0.0
1.685AspIle: 1.685 ± 0.842
8.989AspLys: 8.989 ± 1.23
6.18AspLeu: 6.18 ± 0.928
1.124AspMet: 1.124 ± 1.088
2.247AspAsn: 2.247 ± 1.482
5.056AspPro: 5.056 ± 0.894
2.247AspGln: 2.247 ± 0.693
1.685AspArg: 1.685 ± 1.179
2.247AspSer: 2.247 ± 0.986
1.685AspThr: 1.685 ± 0.617
2.809AspVal: 2.809 ± 1.34
2.247AspTrp: 2.247 ± 1.112
2.247AspTyr: 2.247 ± 0.693
0.0AspXaa: 0.0 ± 0.0
Glu
4.494GluAla: 4.494 ± 2.086
1.124GluCys: 1.124 ± 0.786
3.371GluAsp: 3.371 ± 1.185
11.798GluGlu: 11.798 ± 2.097
3.371GluPhe: 3.371 ± 1.267
5.618GluGly: 5.618 ± 1.485
1.685GluHis: 1.685 ± 0.617
2.247GluIle: 2.247 ± 0.982
2.247GluLys: 2.247 ± 0.693
7.303GluLeu: 7.303 ± 0.998
1.124GluMet: 1.124 ± 0.786
5.056GluAsn: 5.056 ± 1.119
1.124GluPro: 1.124 ± 0.493
2.809GluGln: 2.809 ± 1.07
1.685GluArg: 1.685 ± 1.179
2.809GluSer: 2.809 ± 0.795
2.809GluThr: 2.809 ± 0.881
4.494GluVal: 4.494 ± 2.333
0.562GluTrp: 0.562 ± 0.393
2.247GluTyr: 2.247 ± 1.104
0.0GluXaa: 0.0 ± 0.0
Phe
3.933PheAla: 3.933 ± 0.991
1.124PheCys: 1.124 ± 0.786
1.685PheAsp: 1.685 ± 1.179
3.933PheGlu: 3.933 ± 1.297
2.247PhePhe: 2.247 ± 1.536
1.685PheGly: 1.685 ± 0.67
1.685PheHis: 1.685 ± 0.842
2.809PheIle: 2.809 ± 0.883
1.685PheLys: 1.685 ± 0.706
3.933PheLeu: 3.933 ± 1.288
0.562PheMet: 0.562 ± 0.393
2.247PheAsn: 2.247 ± 0.677
2.247PhePro: 2.247 ± 0.693
0.0PheGln: 0.0 ± 0.0
1.124PheArg: 1.124 ± 0.493
3.933PheSer: 3.933 ± 0.689
1.685PheThr: 1.685 ± 1.232
1.124PheVal: 1.124 ± 0.786
0.0PheTrp: 0.0 ± 0.0
0.0PheTyr: 0.0 ± 0.0
0.0PheXaa: 0.0 ± 0.0
Gly
6.18GlyAla: 6.18 ± 1.71
0.562GlyCys: 0.562 ± 0.393
4.494GlyAsp: 4.494 ± 1.083
2.809GlyGlu: 2.809 ± 1.301
2.809GlyPhe: 2.809 ± 1.542
5.618GlyGly: 5.618 ± 0.749
0.562GlyHis: 0.562 ± 0.393
3.933GlyIle: 3.933 ± 1.271
2.247GlyLys: 2.247 ± 1.104
8.427GlyLeu: 8.427 ± 2.017
0.0GlyMet: 0.0 ± 0.0
0.562GlyAsn: 0.562 ± 0.544
4.494GlyPro: 4.494 ± 0.385
5.056GlyGln: 5.056 ± 2.383
1.685GlyArg: 1.685 ± 1.111
1.685GlySer: 1.685 ± 0.482
2.247GlyThr: 2.247 ± 0.986
5.618GlyVal: 5.618 ± 1.519
0.0GlyTrp: 0.0 ± 0.0
1.124GlyTyr: 1.124 ± 0.768
0.0GlyXaa: 0.0 ± 0.0
His
0.562HisAla: 0.562 ± 0.393
1.124HisCys: 1.124 ± 0.786
1.685HisAsp: 1.685 ± 0.842
1.685HisGlu: 1.685 ± 1.054
1.685HisPhe: 1.685 ± 0.617
2.247HisGly: 2.247 ± 0.693
2.247HisHis: 2.247 ± 0.541
1.685HisIle: 1.685 ± 1.111
0.0HisLys: 0.0 ± 0.0
1.124HisLeu: 1.124 ± 0.786
1.685HisMet: 1.685 ± 0.67
0.562HisAsn: 0.562 ± 0.393
1.124HisPro: 1.124 ± 0.69
2.247HisGln: 2.247 ± 0.882
1.685HisArg: 1.685 ± 0.617
1.124HisSer: 1.124 ± 0.493
4.494HisThr: 4.494 ± 1.543
0.0HisVal: 0.0 ± 0.0
1.685HisTrp: 1.685 ± 1.111
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
1.124IleAla: 1.124 ± 0.493
1.685IleCys: 1.685 ± 1.179
3.933IleAsp: 3.933 ± 1.025
3.933IleGlu: 3.933 ± 1.662
1.685IlePhe: 1.685 ± 0.617
2.809IleGly: 2.809 ± 1.271
1.685IleHis: 1.685 ± 0.617
0.562IleIle: 0.562 ± 0.393
1.685IleLys: 1.685 ± 0.706
5.056IleLeu: 5.056 ± 0.811
0.562IleMet: 0.562 ± 0.695
2.247IleAsn: 2.247 ± 1.031
3.371IlePro: 3.371 ± 1.546
1.124IleGln: 1.124 ± 0.493
0.562IleArg: 0.562 ± 0.393
2.247IleSer: 2.247 ± 0.985
0.562IleThr: 0.562 ± 0.544
1.685IleVal: 1.685 ± 0.706
1.124IleTrp: 1.124 ± 0.768
1.685IleTyr: 1.685 ± 0.617
0.0IleXaa: 0.0 ± 0.0
Lys
6.18LysAla: 6.18 ± 2.142
2.247LysCys: 2.247 ± 1.104
2.247LysAsp: 2.247 ± 0.677
4.494LysGlu: 4.494 ± 1.435
1.685LysPhe: 1.685 ± 0.706
4.494LysGly: 4.494 ± 1.512
1.124LysHis: 1.124 ± 0.786
1.685LysIle: 1.685 ± 0.842
8.427LysLys: 8.427 ± 1.021
5.056LysLeu: 5.056 ± 1.593
3.371LysMet: 3.371 ± 0.963
1.685LysAsn: 1.685 ± 0.961
2.809LysPro: 2.809 ± 1.337
2.247LysGln: 2.247 ± 1.104
5.056LysArg: 5.056 ± 0.977
1.685LysSer: 1.685 ± 1.179
5.056LysThr: 5.056 ± 0.844
4.494LysVal: 4.494 ± 1.935
0.0LysTrp: 0.0 ± 0.0
1.685LysTyr: 1.685 ± 0.706
0.0LysXaa: 0.0 ± 0.0
Leu
6.18LeuAla: 6.18 ± 2.853
1.685LeuCys: 1.685 ± 0.67
6.742LeuAsp: 6.742 ± 1.09
5.056LeuGlu: 5.056 ± 1.005
3.371LeuPhe: 3.371 ± 0.963
4.494LeuGly: 4.494 ± 1.611
5.056LeuHis: 5.056 ± 1.777
3.371LeuIle: 3.371 ± 0.694
4.494LeuLys: 4.494 ± 1.664
7.303LeuLeu: 7.303 ± 1.501
5.618LeuMet: 5.618 ± 1.201
7.303LeuAsn: 7.303 ± 2.146
7.865LeuPro: 7.865 ± 0.885
3.933LeuGln: 3.933 ± 1.032
3.933LeuArg: 3.933 ± 1.53
6.18LeuSer: 6.18 ± 1.201
4.494LeuThr: 4.494 ± 0.935
5.618LeuVal: 5.618 ± 1.155
0.0LeuTrp: 0.0 ± 0.0
7.303LeuTyr: 7.303 ± 1.735
0.0LeuXaa: 0.0 ± 0.0
Met
2.247MetAla: 2.247 ± 0.541
0.0MetCys: 0.0 ± 0.0
2.247MetAsp: 2.247 ± 0.677
1.124MetGlu: 1.124 ± 0.493
1.124MetPhe: 1.124 ± 0.493
1.685MetGly: 1.685 ± 0.482
1.124MetHis: 1.124 ± 0.768
0.562MetIle: 0.562 ± 0.544
1.685MetLys: 1.685 ± 0.67
3.933MetLeu: 3.933 ± 1.622
1.124MetMet: 1.124 ± 0.69
2.247MetAsn: 2.247 ± 1.104
1.685MetPro: 1.685 ± 0.617
1.685MetGln: 1.685 ± 0.832
1.685MetArg: 1.685 ± 1.39
0.562MetSer: 0.562 ± 0.544
1.685MetThr: 1.685 ± 0.67
1.685MetVal: 1.685 ± 0.706
1.124MetTrp: 1.124 ± 0.864
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.809AsnAla: 2.809 ± 0.942
0.0AsnCys: 0.0 ± 0.0
0.0AsnAsp: 0.0 ± 0.0
3.371AsnGlu: 3.371 ± 1.329
1.685AsnPhe: 1.685 ± 1.179
1.124AsnGly: 1.124 ± 1.088
0.562AsnHis: 0.562 ± 0.544
2.247AsnIle: 2.247 ± 0.693
2.809AsnLys: 2.809 ± 0.881
5.056AsnLeu: 5.056 ± 1.403
0.562AsnMet: 0.562 ± 0.446
1.685AsnAsn: 1.685 ± 0.706
2.809AsnPro: 2.809 ± 2.016
2.247AsnGln: 2.247 ± 0.541
3.371AsnArg: 3.371 ± 0.891
3.371AsnSer: 3.371 ± 1.185
2.247AsnThr: 2.247 ± 1.482
2.809AsnVal: 2.809 ± 1.473
0.562AsnTrp: 0.562 ± 0.393
1.685AsnTyr: 1.685 ± 0.842
0.0AsnXaa: 0.0 ± 0.0
Pro
2.247ProAla: 2.247 ± 2.176
1.124ProCys: 1.124 ± 0.493
9.551ProAsp: 9.551 ± 3.442
2.809ProGlu: 2.809 ± 0.883
2.247ProPhe: 2.247 ± 0.693
6.18ProGly: 6.18 ± 0.904
1.124ProHis: 1.124 ± 0.786
0.562ProIle: 0.562 ± 0.544
5.618ProLys: 5.618 ± 1.142
2.247ProLeu: 2.247 ± 1.192
2.809ProMet: 2.809 ± 1.495
1.124ProAsn: 1.124 ± 0.786
5.618ProPro: 5.618 ± 2.784
2.809ProGln: 2.809 ± 0.892
1.685ProArg: 1.685 ± 0.961
2.809ProSer: 2.809 ± 1.517
2.809ProThr: 2.809 ± 0.43
3.933ProVal: 3.933 ± 1.326
0.0ProTrp: 0.0 ± 0.0
2.809ProTyr: 2.809 ± 0.43
0.0ProXaa: 0.0 ± 0.0
Gln
3.371GlnAla: 3.371 ± 0.62
0.0GlnCys: 0.0 ± 0.0
1.685GlnAsp: 1.685 ± 0.617
3.933GlnGlu: 3.933 ± 1.125
2.809GlnPhe: 2.809 ± 1.153
1.124GlnGly: 1.124 ± 0.786
2.247GlnHis: 2.247 ± 1.308
3.933GlnIle: 3.933 ± 0.991
2.809GlnLys: 2.809 ± 1.246
4.494GlnLeu: 4.494 ± 1.435
2.247GlnMet: 2.247 ± 0.911
2.247GlnAsn: 2.247 ± 1.192
1.685GlnPro: 1.685 ± 0.961
1.685GlnGln: 1.685 ± 1.179
2.247GlnArg: 2.247 ± 0.693
1.124GlnSer: 1.124 ± 0.786
2.809GlnThr: 2.809 ± 1.153
2.247GlnVal: 2.247 ± 0.541
0.562GlnTrp: 0.562 ± 0.393
0.562GlnTyr: 0.562 ± 0.446
0.0GlnXaa: 0.0 ± 0.0
Arg
1.124ArgAla: 1.124 ± 0.768
2.809ArgCys: 2.809 ± 1.433
2.247ArgAsp: 2.247 ± 1.379
2.809ArgGlu: 2.809 ± 0.795
2.247ArgPhe: 2.247 ± 0.693
1.124ArgGly: 1.124 ± 0.493
2.809ArgHis: 2.809 ± 1.337
2.247ArgIle: 2.247 ± 1.572
3.933ArgLys: 3.933 ± 1.416
1.124ArgLeu: 1.124 ± 0.768
2.809ArgMet: 2.809 ± 0.451
0.0ArgAsn: 0.0 ± 0.0
1.124ArgPro: 1.124 ± 0.768
2.809ArgGln: 2.809 ± 1.337
4.494ArgArg: 4.494 ± 1.245
1.685ArgSer: 1.685 ± 0.842
1.124ArgThr: 1.124 ± 0.786
3.933ArgVal: 3.933 ± 1.292
2.247ArgTrp: 2.247 ± 1.536
4.494ArgTyr: 4.494 ± 1.664
0.0ArgXaa: 0.0 ± 0.0
Ser
7.865SerAla: 7.865 ± 1.075
2.247SerCys: 2.247 ± 1.698
1.685SerAsp: 1.685 ± 0.961
0.562SerGlu: 0.562 ± 0.393
1.685SerPhe: 1.685 ± 0.67
3.933SerGly: 3.933 ± 1.01
1.685SerHis: 1.685 ± 0.617
2.809SerIle: 2.809 ± 0.912
2.809SerLys: 2.809 ± 1.246
7.303SerLeu: 7.303 ± 2.247
0.0SerMet: 0.0 ± 0.0
0.562SerAsn: 0.562 ± 0.393
2.809SerPro: 2.809 ± 1.353
5.618SerGln: 5.618 ± 2.361
2.809SerArg: 2.809 ± 1.337
5.056SerSer: 5.056 ± 2.529
6.742SerThr: 6.742 ± 3.845
2.247SerVal: 2.247 ± 1.121
2.247SerTrp: 2.247 ± 0.677
1.124SerTyr: 1.124 ± 0.493
0.0SerXaa: 0.0 ± 0.0
Thr
0.562ThrAla: 0.562 ± 0.446
1.124ThrCys: 1.124 ± 1.506
0.562ThrAsp: 0.562 ± 0.393
3.933ThrGlu: 3.933 ± 1.627
2.247ThrPhe: 2.247 ± 0.693
1.685ThrGly: 1.685 ± 1.088
0.0ThrHis: 0.0 ± 0.0
1.124ThrIle: 1.124 ± 1.088
3.933ThrLys: 3.933 ± 1.025
7.303ThrLeu: 7.303 ± 0.611
0.562ThrMet: 0.562 ± 0.393
3.933ThrAsn: 3.933 ± 0.763
6.18ThrPro: 6.18 ± 0.993
2.809ThrGln: 2.809 ± 1.153
1.124ThrArg: 1.124 ± 0.493
6.742ThrSer: 6.742 ± 2.808
5.618ThrThr: 5.618 ± 0.967
4.494ThrVal: 4.494 ± 1.083
1.124ThrTrp: 1.124 ± 0.768
1.685ThrTyr: 1.685 ± 1.39
0.0ThrXaa: 0.0 ± 0.0
Val
1.685ValAla: 1.685 ± 0.854
1.685ValCys: 1.685 ± 0.832
2.247ValAsp: 2.247 ± 1.572
4.494ValGlu: 4.494 ± 1.585
2.809ValPhe: 2.809 ± 1.022
6.18ValGly: 6.18 ± 1.903
1.124ValHis: 1.124 ± 0.493
1.124ValIle: 1.124 ± 0.493
2.809ValLys: 2.809 ± 1.392
5.056ValLeu: 5.056 ± 1.895
1.124ValMet: 1.124 ± 0.786
2.809ValAsn: 2.809 ± 0.942
4.494ValPro: 4.494 ± 1.171
1.685ValGln: 1.685 ± 0.617
2.247ValArg: 2.247 ± 1.192
8.989ValSer: 8.989 ± 1.802
3.371ValThr: 3.371 ± 1.48
3.371ValVal: 3.371 ± 0.694
2.247ValTrp: 2.247 ± 1.379
1.124ValTyr: 1.124 ± 1.088
0.0ValXaa: 0.0 ± 0.0
Trp
3.371TrpAla: 3.371 ± 1.504
1.124TrpCys: 1.124 ± 0.864
1.685TrpAsp: 1.685 ± 0.832
2.247TrpGlu: 2.247 ± 0.541
0.562TrpPhe: 0.562 ± 0.753
0.562TrpGly: 0.562 ± 0.753
0.0TrpHis: 0.0 ± 0.0
1.124TrpIle: 1.124 ± 0.768
2.247TrpLys: 2.247 ± 0.693
1.124TrpLeu: 1.124 ± 0.786
1.124TrpMet: 1.124 ± 0.768
1.124TrpAsn: 1.124 ± 0.69
0.0TrpPro: 0.0 ± 0.0
0.562TrpGln: 0.562 ± 0.393
0.0TrpArg: 0.0 ± 0.0
0.562TrpSer: 0.562 ± 0.544
0.0TrpThr: 0.0 ± 0.0
0.562TrpVal: 0.562 ± 0.544
0.562TrpTrp: 0.562 ± 0.393
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.371TyrAla: 3.371 ± 1.587
2.247TyrCys: 2.247 ± 2.127
0.0TyrAsp: 0.0 ± 0.0
0.562TyrGlu: 0.562 ± 0.544
1.124TyrPhe: 1.124 ± 1.088
3.933TyrGly: 3.933 ± 0.633
3.371TyrHis: 3.371 ± 0.469
1.124TyrIle: 1.124 ± 0.493
2.247TyrLys: 2.247 ± 0.882
5.618TyrLeu: 5.618 ± 1.201
1.685TyrMet: 1.685 ± 0.617
0.0TyrAsn: 0.0 ± 0.0
1.124TyrPro: 1.124 ± 1.088
0.0TyrGln: 0.0 ± 0.0
1.685TyrArg: 1.685 ± 0.617
0.562TyrSer: 0.562 ± 0.544
4.494TyrThr: 4.494 ± 1.078
1.124TyrVal: 1.124 ± 0.786
0.562TyrTrp: 0.562 ± 0.393
1.124TyrTyr: 1.124 ± 0.768
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1781 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski