Amino acid dipepetide frequency for Zobellia galactanivorans (strain DSM 12802 / CCUG 47099 / CIP 106680 / NCIMB 13871 / Dsij)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.599AlaAla: 4.599 ± 0.066	0.578AlaCys: 0.578 ± 0.021	3.904AlaAsp: 3.904 ± 0.062	4.244AlaGlu: 4.244 ± 0.064	3.244AlaPhe: 3.244 ± 0.05	4.366AlaGly: 4.366 ± 0.102	1.288AlaHis: 1.288 ± 0.028	5.006AlaIle: 5.006 ± 0.064	4.489AlaLys: 4.489 ± 0.074	6.591AlaLeu: 6.591 ± 0.079	1.634AlaMet: 1.634 ± 0.038	3.469AlaAsn: 3.469 ± 0.057	2.406AlaPro: 2.406 ± 0.044	2.628AlaGln: 2.628 ± 0.043	2.197AlaArg: 2.197 ± 0.039	4.535AlaSer: 4.535 ± 0.062	3.824AlaThr: 3.824 ± 0.075	4.245AlaVal: 4.245 ± 0.06	0.691AlaTrp: 0.691 ± 0.023	2.816AlaTyr: 2.816 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.493CysAla: 0.493 ± 0.025	0.1CysCys: 0.1 ± 0.008	0.422CysAsp: 0.422 ± 0.019	0.428CysGlu: 0.428 ± 0.018	0.41CysPhe: 0.41 ± 0.015	0.573CysGly: 0.573 ± 0.019	0.203CysHis: 0.203 ± 0.013	0.528CysIle: 0.528 ± 0.021	0.432CysLys: 0.432 ± 0.018	0.648CysLeu: 0.648 ± 0.024	0.16CysMet: 0.16 ± 0.01	0.381CysAsn: 0.381 ± 0.018	0.299CysPro: 0.299 ± 0.016	0.238CysGln: 0.238 ± 0.013	0.21CysArg: 0.21 ± 0.012	0.595CysSer: 0.595 ± 0.022	0.475CysThr: 0.475 ± 0.03	0.412CysVal: 0.412 ± 0.015	0.071CysTrp: 0.071 ± 0.007	0.307CysTyr: 0.307 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	4.178AspAla: 4.178 ± 0.078	0.407AspCys: 0.407 ± 0.019	3.436AspAsp: 3.436 ± 0.075	3.795AspGlu: 3.795 ± 0.049	3.817AspPhe: 3.817 ± 0.052	4.894AspGly: 4.894 ± 0.139	1.104AspHis: 1.104 ± 0.029	4.381AspIle: 4.381 ± 0.054	3.915AspLys: 3.915 ± 0.053	5.433AspLeu: 5.433 ± 0.079	1.29AspMet: 1.29 ± 0.03	3.116AspAsn: 3.116 ± 0.062	2.285AspPro: 2.285 ± 0.055	1.842AspGln: 1.842 ± 0.034	2.322AspArg: 2.322 ± 0.037	3.326AspSer: 3.326 ± 0.061	3.117AspThr: 3.117 ± 0.071	3.626AspVal: 3.626 ± 0.06	0.886AspTrp: 0.886 ± 0.026	2.934AspTyr: 2.934 ± 0.045	0.0AspXaa: 0.0 ± 0.0
Glu	4.807GluAla: 4.807 ± 0.068	0.32GluCys: 0.32 ± 0.014	3.702GluAsp: 3.702 ± 0.061	5.048GluGlu: 5.048 ± 0.083	2.739GluPhe: 2.739 ± 0.041	4.477GluGly: 4.477 ± 0.05	1.226GluHis: 1.226 ± 0.027	4.93GluIle: 4.93 ± 0.056	5.558GluLys: 5.558 ± 0.078	6.208GluLeu: 6.208 ± 0.082	1.59GluMet: 1.59 ± 0.033	4.371GluAsn: 4.371 ± 0.054	1.85GluPro: 1.85 ± 0.033	2.212GluGln: 2.212 ± 0.048	2.816GluArg: 2.816 ± 0.047	3.438GluSer: 3.438 ± 0.044	3.679GluThr: 3.679 ± 0.046	4.561GluVal: 4.561 ± 0.061	0.765GluTrp: 0.765 ± 0.022	2.295GluTyr: 2.295 ± 0.039	0.0GluXaa: 0.0 ± 0.0
Phe	2.977PheAla: 2.977 ± 0.046	0.413PheCys: 0.413 ± 0.015	3.46PheAsp: 3.46 ± 0.042	3.323PheGlu: 3.323 ± 0.049	2.709PhePhe: 2.709 ± 0.05	3.65PheGly: 3.65 ± 0.06	0.816PheHis: 0.816 ± 0.026	3.267PheIle: 3.267 ± 0.05	3.427PheLys: 3.427 ± 0.06	4.646PheLeu: 4.646 ± 0.062	1.164PheMet: 1.164 ± 0.026	2.82PheAsn: 2.82 ± 0.044	1.801PhePro: 1.801 ± 0.035	1.468PheGln: 1.468 ± 0.029	1.753PheArg: 1.753 ± 0.034	3.854PheSer: 3.854 ± 0.064	2.993PheThr: 2.993 ± 0.046	3.034PheVal: 3.034 ± 0.045	0.616PheTrp: 0.616 ± 0.019	2.089PheTyr: 2.089 ± 0.039	0.0PheXaa: 0.0 ± 0.0
Gly	4.644GlyAla: 4.644 ± 0.079	0.613GlyCys: 0.613 ± 0.024	3.967GlyAsp: 3.967 ± 0.081	4.207GlyGlu: 4.207 ± 0.051	3.769GlyPhe: 3.769 ± 0.043	5.035GlyGly: 5.035 ± 0.085	1.363GlyHis: 1.363 ± 0.028	5.377GlyIle: 5.377 ± 0.065	5.32GlyLys: 5.32 ± 0.067	6.486GlyLeu: 6.486 ± 0.078	1.678GlyMet: 1.678 ± 0.035	3.93GlyAsn: 3.93 ± 0.07	1.768GlyPro: 1.768 ± 0.033	2.258GlyGln: 2.258 ± 0.038	2.555GlyArg: 2.555 ± 0.046	4.707GlySer: 4.707 ± 0.084	4.425GlyThr: 4.425 ± 0.116	4.696GlyVal: 4.696 ± 0.062	0.936GlyTrp: 0.936 ± 0.029	3.224GlyTyr: 3.224 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	1.025HisAla: 1.025 ± 0.027	0.184HisCys: 0.184 ± 0.012	0.91HisAsp: 0.91 ± 0.023	0.989HisGlu: 0.989 ± 0.027	1.128HisPhe: 1.128 ± 0.027	1.212HisGly: 1.212 ± 0.026	0.501HisHis: 0.501 ± 0.018	1.469HisIle: 1.469 ± 0.033	1.212HisLys: 1.212 ± 0.032	1.868HisLeu: 1.868 ± 0.038	0.43HisMet: 0.43 ± 0.017	0.907HisAsn: 0.907 ± 0.026	0.98HisPro: 0.98 ± 0.025	0.662HisGln: 0.662 ± 0.019	0.779HisArg: 0.779 ± 0.024	1.087HisSer: 1.087 ± 0.029	1.081HisThr: 1.081 ± 0.028	0.98HisVal: 0.98 ± 0.028	0.277HisTrp: 0.277 ± 0.012	0.848HisTyr: 0.848 ± 0.026	0.0HisXaa: 0.0 ± 0.0
Ile	5.225IleAla: 5.225 ± 0.069	0.602IleCys: 0.602 ± 0.033	4.835IleAsp: 4.835 ± 0.061	4.776IleGlu: 4.776 ± 0.059	3.165IlePhe: 3.165 ± 0.05	5.04IleGly: 5.04 ± 0.059	1.194IleHis: 1.194 ± 0.026	4.421IleIle: 4.421 ± 0.062	4.757IleLys: 4.757 ± 0.064	6.082IleLeu: 6.082 ± 0.077	1.302IleMet: 1.302 ± 0.027	3.718IleAsn: 3.718 ± 0.054	3.017IlePro: 3.017 ± 0.046	2.151IleGln: 2.151 ± 0.041	2.626IleArg: 2.626 ± 0.045	5.135IleSer: 5.135 ± 0.067	4.302IleThr: 4.302 ± 0.064	4.343IleVal: 4.343 ± 0.058	0.728IleTrp: 0.728 ± 0.023	2.527IleTyr: 2.527 ± 0.038	0.0IleXaa: 0.0 ± 0.0
Lys	4.836LysAla: 4.836 ± 0.072	0.314LysCys: 0.314 ± 0.016	4.179LysAsp: 4.179 ± 0.051	5.881LysGlu: 5.881 ± 0.077	2.692LysPhe: 2.692 ± 0.043	4.974LysGly: 4.974 ± 0.065	1.277LysHis: 1.277 ± 0.033	5.061LysIle: 5.061 ± 0.065	6.357LysLys: 6.357 ± 0.085	5.995LysLeu: 5.995 ± 0.072	1.826LysMet: 1.826 ± 0.037	4.635LysAsn: 4.635 ± 0.058	2.394LysPro: 2.394 ± 0.038	2.261LysGln: 2.261 ± 0.04	2.956LysArg: 2.956 ± 0.048	4.124LysSer: 4.124 ± 0.06	4.353LysThr: 4.353 ± 0.057	4.496LysVal: 4.496 ± 0.06	0.859LysTrp: 0.859 ± 0.025	2.722LysTyr: 2.722 ± 0.044	0.0LysXaa: 0.0 ± 0.0
Leu	6.224LeuAla: 6.224 ± 0.068	0.735LeuCys: 0.735 ± 0.021	5.409LeuAsp: 5.409 ± 0.075	6.061LeuGlu: 6.061 ± 0.06	4.712LeuPhe: 4.712 ± 0.071	6.409LeuGly: 6.409 ± 0.069	1.576LeuHis: 1.576 ± 0.037	5.73LeuIle: 5.73 ± 0.075	7.318LeuLys: 7.318 ± 0.081	8.632LeuLeu: 8.632 ± 0.114	2.055LeuMet: 2.055 ± 0.038	5.2LeuAsn: 5.2 ± 0.064	3.863LeuPro: 3.863 ± 0.049	3.008LeuGln: 3.008 ± 0.044	3.546LeuArg: 3.546 ± 0.047	6.75LeuSer: 6.75 ± 0.066	5.156LeuThr: 5.156 ± 0.06	5.64LeuVal: 5.64 ± 0.066	1.017LeuTrp: 1.017 ± 0.03	3.292LeuTyr: 3.292 ± 0.052	0.0LeuXaa: 0.0 ± 0.0
Met	1.901MetAla: 1.901 ± 0.04	0.14MetCys: 0.14 ± 0.008	1.252MetAsp: 1.252 ± 0.029	1.486MetGlu: 1.486 ± 0.029	0.83MetPhe: 0.83 ± 0.027	1.766MetGly: 1.766 ± 0.034	0.422MetHis: 0.422 ± 0.015	1.268MetIle: 1.268 ± 0.031	2.009MetLys: 2.009 ± 0.036	1.898MetLeu: 1.898 ± 0.043	0.516MetMet: 0.516 ± 0.019	1.198MetAsn: 1.198 ± 0.029	0.895MetPro: 0.895 ± 0.024	0.829MetGln: 0.829 ± 0.023	0.901MetArg: 0.901 ± 0.021	1.256MetSer: 1.256 ± 0.032	1.165MetThr: 1.165 ± 0.025	1.56MetVal: 1.56 ± 0.034	0.191MetTrp: 0.191 ± 0.011	0.719MetTyr: 0.719 ± 0.021	0.0MetXaa: 0.0 ± 0.0
Asn	3.635AsnAla: 3.635 ± 0.053	0.416AsnCys: 0.416 ± 0.02	3.299AsnAsp: 3.299 ± 0.068	3.449AsnGlu: 3.449 ± 0.049	2.829AsnPhe: 2.829 ± 0.052	4.472AsnGly: 4.472 ± 0.075	1.039AsnHis: 1.039 ± 0.024	4.13AsnIle: 4.13 ± 0.052	3.459AsnLys: 3.459 ± 0.051	4.992AsnLeu: 4.992 ± 0.063	1.142AsnMet: 1.142 ± 0.025	3.079AsnAsn: 3.079 ± 0.059	2.65AsnPro: 2.65 ± 0.047	1.787AsnGln: 1.787 ± 0.036	2.232AsnArg: 2.232 ± 0.039	3.489AsnSer: 3.489 ± 0.051	3.496AsnThr: 3.496 ± 0.057	3.162AsnVal: 3.162 ± 0.051	0.734AsnTrp: 0.734 ± 0.023	2.555AsnTyr: 2.555 ± 0.047	0.0AsnXaa: 0.0 ± 0.0
Pro	2.088ProAla: 2.088 ± 0.044	0.228ProCys: 0.228 ± 0.025	2.505ProAsp: 2.505 ± 0.056	3.247ProGlu: 3.247 ± 0.049	1.931ProPhe: 1.931 ± 0.037	2.262ProGly: 2.262 ± 0.043	0.711ProHis: 0.711 ± 0.022	2.689ProIle: 2.689 ± 0.043	2.705ProLys: 2.705 ± 0.042	3.318ProLeu: 3.318 ± 0.043	0.832ProMet: 0.832 ± 0.026	2.368ProAsn: 2.368 ± 0.041	1.026ProPro: 1.026 ± 0.027	1.256ProGln: 1.256 ± 0.026	1.11ProArg: 1.11 ± 0.028	2.521ProSer: 2.521 ± 0.041	2.11ProThr: 2.11 ± 0.041	2.523ProVal: 2.523 ± 0.048	0.443ProTrp: 0.443 ± 0.015	1.525ProTyr: 1.525 ± 0.032	0.0ProXaa: 0.0 ± 0.0
Gln	2.071GlnAla: 2.071 ± 0.035	0.182GlnCys: 0.182 ± 0.01	1.747GlnAsp: 1.747 ± 0.042	2.358GlnGlu: 2.358 ± 0.042	1.551GlnPhe: 1.551 ± 0.032	2.134GlnGly: 2.134 ± 0.04	0.603GlnHis: 0.603 ± 0.02	2.318GlnIle: 2.318 ± 0.037	2.652GlnLys: 2.652 ± 0.046	3.372GlnLeu: 3.372 ± 0.066	0.863GlnMet: 0.863 ± 0.023	1.986GlnAsn: 1.986 ± 0.036	1.077GlnPro: 1.077 ± 0.026	1.212GlnGln: 1.212 ± 0.034	1.333GlnArg: 1.333 ± 0.029	1.808GlnSer: 1.808 ± 0.03	1.77GlnThr: 1.77 ± 0.034	1.958GlnVal: 1.958 ± 0.036	0.435GlnTrp: 0.435 ± 0.018	1.292GlnTyr: 1.292 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	2.351ArgAla: 2.351 ± 0.045	0.223ArgCys: 0.223 ± 0.013	1.947ArgAsp: 1.947 ± 0.034	2.303ArgGlu: 2.303 ± 0.038	2.146ArgPhe: 2.146 ± 0.038	2.185ArgGly: 2.185 ± 0.045	0.693ArgHis: 0.693 ± 0.019	2.899ArgIle: 2.899 ± 0.045	2.957ArgLys: 2.957 ± 0.044	3.641ArgLeu: 3.641 ± 0.052	0.972ArgMet: 0.972 ± 0.029	2.196ArgAsn: 2.196 ± 0.035	1.508ArgPro: 1.508 ± 0.033	1.22ArgGln: 1.22 ± 0.025	1.434ArgArg: 1.434 ± 0.031	2.274ArgSer: 2.274 ± 0.039	2.087ArgThr: 2.087 ± 0.038	2.216ArgVal: 2.216 ± 0.041	0.499ArgTrp: 0.499 ± 0.018	1.785ArgTyr: 1.785 ± 0.035	0.0ArgXaa: 0.0 ± 0.0
Ser	4.107SerAla: 4.107 ± 0.056	0.661SerCys: 0.661 ± 0.024	3.899SerAsp: 3.899 ± 0.063	4.155SerGlu: 4.155 ± 0.056	3.635SerPhe: 3.635 ± 0.054	5.117SerGly: 5.117 ± 0.083	1.164SerHis: 1.164 ± 0.03	4.841SerIle: 4.841 ± 0.06	4.394SerLys: 4.394 ± 0.058	6.006SerLeu: 6.006 ± 0.072	1.273SerMet: 1.273 ± 0.029	3.372SerAsn: 3.372 ± 0.057	2.41SerPro: 2.41 ± 0.058	1.966SerGln: 1.966 ± 0.035	2.292SerArg: 2.292 ± 0.038	4.277SerSer: 4.277 ± 0.062	3.572SerThr: 3.572 ± 0.059	4.258SerVal: 4.258 ± 0.056	0.742SerTrp: 0.742 ± 0.024	2.867SerTyr: 2.867 ± 0.05	0.0SerXaa: 0.0 ± 0.0
Thr	3.858ThrAla: 3.858 ± 0.065	0.352ThrCys: 0.352 ± 0.014	3.871ThrAsp: 3.871 ± 0.087	3.659ThrGlu: 3.659 ± 0.06	2.825ThrPhe: 2.825 ± 0.044	4.341ThrGly: 4.341 ± 0.069	1.027ThrHis: 1.027 ± 0.027	4.229ThrIle: 4.229 ± 0.067	3.517ThrLys: 3.517 ± 0.051	5.453ThrLeu: 5.453 ± 0.063	1.022ThrMet: 1.022 ± 0.026	2.871ThrAsn: 2.871 ± 0.059	2.712ThrPro: 2.712 ± 0.049	1.812ThrGln: 1.812 ± 0.034	1.745ThrArg: 1.745 ± 0.038	3.744ThrSer: 3.744 ± 0.063	3.389ThrThr: 3.389 ± 0.059	4.066ThrVal: 4.066 ± 0.093	0.681ThrTrp: 0.681 ± 0.033	2.531ThrTyr: 2.531 ± 0.064	0.0ThrXaa: 0.0 ± 0.0
Val	4.306ValAla: 4.306 ± 0.057	0.522ValCys: 0.522 ± 0.019	4.021ValAsp: 4.021 ± 0.072	3.925ValGlu: 3.925 ± 0.055	3.286ValPhe: 3.286 ± 0.047	4.138ValGly: 4.138 ± 0.063	1.139ValHis: 1.139 ± 0.033	4.194ValIle: 4.194 ± 0.058	4.025ValLys: 4.025 ± 0.057	6.26ValLeu: 6.26 ± 0.064	1.344ValMet: 1.344 ± 0.036	3.335ValAsn: 3.335 ± 0.053	2.498ValPro: 2.498 ± 0.042	1.968ValGln: 1.968 ± 0.035	2.346ValArg: 2.346 ± 0.045	4.732ValSer: 4.732 ± 0.065	3.545ValThr: 3.545 ± 0.086	4.502ValVal: 4.502 ± 0.078	0.697ValTrp: 0.697 ± 0.024	2.492ValTyr: 2.492 ± 0.045	0.0ValXaa: 0.0 ± 0.0
Trp	0.76TrpAla: 0.76 ± 0.022	0.088TrpCys: 0.088 ± 0.007	0.738TrpAsp: 0.738 ± 0.022	0.767TrpGlu: 0.767 ± 0.024	0.567TrpPhe: 0.567 ± 0.02	0.875TrpGly: 0.875 ± 0.025	0.304TrpHis: 0.304 ± 0.014	0.677TrpIle: 0.677 ± 0.025	0.925TrpLys: 0.925 ± 0.024	1.076TrpLeu: 1.076 ± 0.028	0.342TrpMet: 0.342 ± 0.013	0.706TrpAsn: 0.706 ± 0.021	0.389TrpPro: 0.389 ± 0.016	0.483TrpGln: 0.483 ± 0.019	0.484TrpArg: 0.484 ± 0.019	0.76TrpSer: 0.76 ± 0.026	0.614TrpThr: 0.614 ± 0.02	0.739TrpVal: 0.739 ± 0.022	0.188TrpTrp: 0.188 ± 0.012	0.487TrpTyr: 0.487 ± 0.02	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.668TyrAla: 2.668 ± 0.041	0.308TyrCys: 0.308 ± 0.013	2.601TyrAsp: 2.601 ± 0.047	2.491TyrGlu: 2.491 ± 0.044	2.296TyrPhe: 2.296 ± 0.041	3.038TyrGly: 3.038 ± 0.053	0.877TyrHis: 0.877 ± 0.025	2.532TyrIle: 2.532 ± 0.041	2.767TyrLys: 2.767 ± 0.044	3.726TyrLeu: 3.726 ± 0.054	0.768TyrMet: 0.768 ± 0.02	2.386TyrAsn: 2.386 ± 0.049	1.57TyrPro: 1.57 ± 0.031	1.462TyrGln: 1.462 ± 0.035	1.898TyrArg: 1.898 ± 0.039	2.596TyrSer: 2.596 ± 0.044	2.554TyrThr: 2.554 ± 0.064	2.259TyrVal: 2.259 ± 0.035	0.51TyrTrp: 0.51 ± 0.019	1.761TyrTyr: 1.761 ± 0.038	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4708 proteins (1661998 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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