Amino acid dipepetide frequency for Chryseobacterium koreense CCUG 49689

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	4.606AlaAla: 4.606 ± 0.103	0.496AlaCys: 0.496 ± 0.024	3.541AlaAsp: 3.541 ± 0.066	4.829AlaGlu: 4.829 ± 0.083	3.214AlaPhe: 3.214 ± 0.062	4.505AlaGly: 4.505 ± 0.079	0.992AlaHis: 0.992 ± 0.034	4.931AlaIle: 4.931 ± 0.081	5.413AlaLys: 5.413 ± 0.101	5.795AlaLeu: 5.795 ± 0.081	1.717AlaMet: 1.717 ± 0.046	3.546AlaAsn: 3.546 ± 0.086	1.84AlaPro: 1.84 ± 0.047	2.54AlaGln: 2.54 ± 0.061	2.032AlaArg: 2.032 ± 0.056	3.615AlaSer: 3.615 ± 0.066	3.568AlaThr: 3.568 ± 0.08	4.484AlaVal: 4.484 ± 0.071	0.534AlaTrp: 0.534 ± 0.025	2.186AlaTyr: 2.186 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	0.466CysAla: 0.466 ± 0.023	0.106CysCys: 0.106 ± 0.009	0.385CysAsp: 0.385 ± 0.02	0.484CysGlu: 0.484 ± 0.027	0.404CysPhe: 0.404 ± 0.022	0.688CysGly: 0.688 ± 0.033	0.176CysHis: 0.176 ± 0.017	0.559CysIle: 0.559 ± 0.028	0.488CysLys: 0.488 ± 0.024	0.576CysLeu: 0.576 ± 0.026	0.131CysMet: 0.131 ± 0.012	0.377CysAsn: 0.377 ± 0.02	0.349CysPro: 0.349 ± 0.023	0.198CysGln: 0.198 ± 0.014	0.246CysArg: 0.246 ± 0.016	0.534CysSer: 0.534 ± 0.028	0.388CysThr: 0.388 ± 0.025	0.442CysVal: 0.442 ± 0.023	0.044CysTrp: 0.044 ± 0.006	0.255CysTyr: 0.255 ± 0.017	0.0CysXaa: 0.0 ± 0.0
Asp	3.503AspAla: 3.503 ± 0.069	0.394AspCys: 0.394 ± 0.02	2.687AspAsp: 2.687 ± 0.055	4.168AspGlu: 4.168 ± 0.085	4.086AspPhe: 4.086 ± 0.069	3.551AspGly: 3.551 ± 0.07	1.016AspHis: 1.016 ± 0.036	3.687AspIle: 3.687 ± 0.062	3.911AspLys: 3.911 ± 0.076	5.399AspLeu: 5.399 ± 0.08	1.079AspMet: 1.079 ± 0.035	2.408AspAsn: 2.408 ± 0.056	1.756AspPro: 1.756 ± 0.045	1.845AspGln: 1.845 ± 0.047	1.988AspArg: 1.988 ± 0.05	2.983AspSer: 2.983 ± 0.064	2.123AspThr: 2.123 ± 0.048	3.149AspVal: 3.149 ± 0.064	0.707AspTrp: 0.707 ± 0.025	2.581AspTyr: 2.581 ± 0.055	0.0AspXaa: 0.0 ± 0.0
Glu	3.791GluAla: 3.791 ± 0.076	0.321GluCys: 0.321 ± 0.02	3.344GluAsp: 3.344 ± 0.066	4.975GluGlu: 4.975 ± 0.114	3.36GluPhe: 3.36 ± 0.069	3.43GluGly: 3.43 ± 0.065	1.066GluHis: 1.066 ± 0.036	6.436GluIle: 6.436 ± 0.101	7.312GluLys: 7.312 ± 0.111	5.954GluLeu: 5.954 ± 0.098	1.926GluMet: 1.926 ± 0.05	5.462GluAsn: 5.462 ± 0.089	1.606GluPro: 1.606 ± 0.05	2.321GluGln: 2.321 ± 0.064	2.591GluArg: 2.591 ± 0.063	3.327GluSer: 3.327 ± 0.056	3.604GluThr: 3.604 ± 0.062	4.252GluVal: 4.252 ± 0.073	0.65GluTrp: 0.65 ± 0.03	2.395GluTyr: 2.395 ± 0.051	0.0GluXaa: 0.0 ± 0.0
Phe	3.63PheAla: 3.63 ± 0.066	0.488PheCys: 0.488 ± 0.022	3.277PheAsp: 3.277 ± 0.064	3.521PheGlu: 3.521 ± 0.079	3.155PhePhe: 3.155 ± 0.07	4.009PheGly: 4.009 ± 0.075	1.068PheHis: 1.068 ± 0.037	3.788PheIle: 3.788 ± 0.068	3.604PheLys: 3.604 ± 0.06	5.329PheLeu: 5.329 ± 0.097	1.281PheMet: 1.281 ± 0.035	3.047PheAsn: 3.047 ± 0.059	2.106PhePro: 2.106 ± 0.05	1.948PheGln: 1.948 ± 0.049	2.19PheArg: 2.19 ± 0.053	4.341PheSer: 4.341 ± 0.078	2.981PheThr: 2.981 ± 0.057	3.314PheVal: 3.314 ± 0.068	0.705PheTrp: 0.705 ± 0.036	2.293PheTyr: 2.293 ± 0.057	0.0PheXaa: 0.0 ± 0.0
Gly	4.095GlyAla: 4.095 ± 0.078	0.511GlyCys: 0.511 ± 0.031	3.108GlyAsp: 3.108 ± 0.068	3.683GlyGlu: 3.683 ± 0.064	3.741GlyPhe: 3.741 ± 0.073	4.471GlyGly: 4.471 ± 0.109	0.96GlyHis: 0.96 ± 0.031	5.703GlyIle: 5.703 ± 0.103	5.917GlyLys: 5.917 ± 0.09	5.443GlyLeu: 5.443 ± 0.087	1.706GlyMet: 1.706 ± 0.04	4.115GlyAsn: 4.115 ± 0.079	1.244GlyPro: 1.244 ± 0.041	1.952GlyGln: 1.952 ± 0.046	2.209GlyArg: 2.209 ± 0.058	3.808GlySer: 3.808 ± 0.067	4.112GlyThr: 4.112 ± 0.098	3.941GlyVal: 3.941 ± 0.066	0.764GlyTrp: 0.764 ± 0.028	2.636GlyTyr: 2.636 ± 0.069	0.0GlyXaa: 0.0 ± 0.0
His	0.977HisAla: 0.977 ± 0.035	0.181HisCys: 0.181 ± 0.014	0.811HisAsp: 0.811 ± 0.027	1.053HisGlu: 1.053 ± 0.039	1.243HisPhe: 1.243 ± 0.04	1.061HisGly: 1.061 ± 0.033	0.533HisHis: 0.533 ± 0.027	1.231HisIle: 1.231 ± 0.03	1.135HisLys: 1.135 ± 0.033	1.796HisLeu: 1.796 ± 0.047	0.296HisMet: 0.296 ± 0.016	0.819HisAsn: 0.819 ± 0.029	0.896HisPro: 0.896 ± 0.036	0.832HisGln: 0.832 ± 0.034	0.656HisArg: 0.656 ± 0.028	1.095HisSer: 1.095 ± 0.038	0.82HisThr: 0.82 ± 0.03	0.754HisVal: 0.754 ± 0.028	0.204HisTrp: 0.204 ± 0.014	0.815HisTyr: 0.815 ± 0.032	0.0HisXaa: 0.0 ± 0.0
Ile	5.407IleAla: 5.407 ± 0.089	0.647IleCys: 0.647 ± 0.03	4.341IleAsp: 4.341 ± 0.065	5.011IleGlu: 5.011 ± 0.096	4.348IlePhe: 4.348 ± 0.091	4.934IleGly: 4.934 ± 0.085	1.352IleHis: 1.352 ± 0.041	5.614IleIle: 5.614 ± 0.091	5.385IleLys: 5.385 ± 0.075	7.551IleLeu: 7.551 ± 0.123	1.396IleMet: 1.396 ± 0.042	4.241IleAsn: 4.241 ± 0.079	3.409IlePro: 3.409 ± 0.061	2.682IleGln: 2.682 ± 0.055	2.783IleArg: 2.783 ± 0.067	6.151IleSer: 6.151 ± 0.093	4.178IleThr: 4.178 ± 0.075	4.366IleVal: 4.366 ± 0.076	0.694IleTrp: 0.694 ± 0.029	2.936IleTyr: 2.936 ± 0.059	0.0IleXaa: 0.0 ± 0.0
Lys	4.779LysAla: 4.779 ± 0.083	0.398LysCys: 0.398 ± 0.022	4.529LysAsp: 4.529 ± 0.072	5.948LysGlu: 5.948 ± 0.106	3.714LysPhe: 3.714 ± 0.071	4.307LysGly: 4.307 ± 0.068	1.238LysHis: 1.238 ± 0.035	7.513LysIle: 7.513 ± 0.098	7.308LysLys: 7.308 ± 0.106	6.668LysLeu: 6.668 ± 0.087	2.546LysMet: 2.546 ± 0.05	6.067LysAsn: 6.067 ± 0.085	2.752LysPro: 2.752 ± 0.06	2.648LysGln: 2.648 ± 0.061	2.709LysArg: 2.709 ± 0.067	5.024LysSer: 5.024 ± 0.096	4.905LysThr: 4.905 ± 0.077	4.936LysVal: 4.936 ± 0.076	0.723LysTrp: 0.723 ± 0.03	3.287LysTyr: 3.287 ± 0.059	0.0LysXaa: 0.0 ± 0.0
Leu	6.015LeuAla: 6.015 ± 0.092	0.678LeuCys: 0.678 ± 0.027	4.793LeuAsp: 4.793 ± 0.077	6.084LeuGlu: 6.084 ± 0.11	4.847LeuPhe: 4.847 ± 0.089	5.867LeuGly: 5.867 ± 0.094	1.53LeuHis: 1.53 ± 0.047	6.578LeuIle: 6.578 ± 0.116	8.01LeuLys: 8.01 ± 0.105	8.202LeuLeu: 8.202 ± 0.125	2.408LeuMet: 2.408 ± 0.057	5.301LeuAsn: 5.301 ± 0.086	3.618LeuPro: 3.618 ± 0.066	3.378LeuGln: 3.378 ± 0.063	3.261LeuArg: 3.261 ± 0.058	6.292LeuSer: 6.292 ± 0.103	4.688LeuThr: 4.688 ± 0.078	5.383LeuVal: 5.383 ± 0.085	0.776LeuTrp: 0.776 ± 0.029	3.014LeuTyr: 3.014 ± 0.068	0.0LeuXaa: 0.0 ± 0.0
Met	1.664MetAla: 1.664 ± 0.047	0.124MetCys: 0.124 ± 0.013	1.32MetAsp: 1.32 ± 0.043	1.626MetGlu: 1.626 ± 0.051	1.006MetPhe: 1.006 ± 0.039	1.518MetGly: 1.518 ± 0.048	0.404MetHis: 0.404 ± 0.022	1.724MetIle: 1.724 ± 0.044	2.704MetLys: 2.704 ± 0.057	2.105MetLeu: 2.105 ± 0.05	0.811MetMet: 0.811 ± 0.032	1.581MetAsn: 1.581 ± 0.044	0.912MetPro: 0.912 ± 0.03	0.886MetGln: 0.886 ± 0.032	0.964MetArg: 0.964 ± 0.03	1.456MetSer: 1.456 ± 0.044	1.297MetThr: 1.297 ± 0.036	1.558MetVal: 1.558 ± 0.044	0.17MetTrp: 0.17 ± 0.015	0.683MetTyr: 0.683 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	4.02AsnAla: 4.02 ± 0.07	0.448AsnCys: 0.448 ± 0.027	2.855AsnAsp: 2.855 ± 0.061	3.582AsnGlu: 3.582 ± 0.065	3.696AsnPhe: 3.696 ± 0.081	4.153AsnGly: 4.153 ± 0.091	1.136AsnHis: 1.136 ± 0.037	4.744AsnIle: 4.744 ± 0.073	3.805AsnLys: 3.805 ± 0.071	5.939AsnLeu: 5.939 ± 0.098	1.314AsnMet: 1.314 ± 0.042	3.324AsnAsn: 3.324 ± 0.081	3.18AsnPro: 3.18 ± 0.079	2.413AsnGln: 2.413 ± 0.056	2.236AsnArg: 2.236 ± 0.05	3.9AsnSer: 3.9 ± 0.08	3.031AsnThr: 3.031 ± 0.072	3.443AsnVal: 3.443 ± 0.08	0.733AsnTrp: 0.733 ± 0.027	2.901AsnTyr: 2.901 ± 0.064	0.0AsnXaa: 0.0 ± 0.0
Pro	2.278ProAla: 2.278 ± 0.061	0.219ProCys: 0.219 ± 0.016	2.054ProAsp: 2.054 ± 0.048	3.277ProGlu: 3.277 ± 0.069	1.986ProPhe: 1.986 ± 0.053	1.966ProGly: 1.966 ± 0.05	0.633ProHis: 0.633 ± 0.028	2.577ProIle: 2.577 ± 0.058	2.917ProLys: 2.917 ± 0.062	2.826ProLeu: 2.826 ± 0.055	0.861ProMet: 0.861 ± 0.031	2.334ProAsn: 2.334 ± 0.059	0.879ProPro: 0.879 ± 0.04	1.318ProGln: 1.318 ± 0.042	0.996ProArg: 0.996 ± 0.039	2.016ProSer: 2.016 ± 0.054	2.029ProThr: 2.029 ± 0.063	2.551ProVal: 2.551 ± 0.056	0.314ProTrp: 0.314 ± 0.021	1.366ProTyr: 1.366 ± 0.042	0.0ProXaa: 0.0 ± 0.0
Gln	1.853GlnAla: 1.853 ± 0.053	0.174GlnCys: 0.174 ± 0.014	1.624GlnAsp: 1.624 ± 0.044	2.302GlnGlu: 2.302 ± 0.056	1.787GlnPhe: 1.787 ± 0.043	1.808GlnGly: 1.808 ± 0.054	0.604GlnHis: 0.604 ± 0.027	3.115GlnIle: 3.115 ± 0.067	3.796GlnLys: 3.796 ± 0.067	3.353GlnLeu: 3.353 ± 0.062	0.959GlnMet: 0.959 ± 0.031	2.831GlnAsn: 2.831 ± 0.063	1.174GlnPro: 1.174 ± 0.045	1.609GlnGln: 1.609 ± 0.051	1.39GlnArg: 1.39 ± 0.035	2.0GlnSer: 2.0 ± 0.047	2.011GlnThr: 2.011 ± 0.052	1.869GlnVal: 1.869 ± 0.048	0.351GlnTrp: 0.351 ± 0.021	1.403GlnTyr: 1.403 ± 0.044	0.0GlnXaa: 0.0 ± 0.0
Arg	1.93ArgAla: 1.93 ± 0.047	0.219ArgCys: 0.219 ± 0.015	1.819ArgAsp: 1.819 ± 0.055	2.525ArgGlu: 2.525 ± 0.061	2.065ArgPhe: 2.065 ± 0.043	1.971ArgGly: 1.971 ± 0.05	0.642ArgHis: 0.642 ± 0.026	3.091ArgIle: 3.091 ± 0.051	3.451ArgLys: 3.451 ± 0.07	2.97ArgLeu: 2.97 ± 0.059	1.037ArgMet: 1.037 ± 0.037	2.604ArgAsn: 2.604 ± 0.051	1.136ArgPro: 1.136 ± 0.039	1.191ArgGln: 1.191 ± 0.039	1.464ArgArg: 1.464 ± 0.047	1.912ArgSer: 1.912 ± 0.046	1.911ArgThr: 1.911 ± 0.043	1.999ArgVal: 1.999 ± 0.05	0.347ArgTrp: 0.347 ± 0.019	1.382ArgTyr: 1.382 ± 0.041	0.0ArgXaa: 0.0 ± 0.0
Ser	4.413SerAla: 4.413 ± 0.092	0.624SerCys: 0.624 ± 0.03	3.374SerAsp: 3.374 ± 0.068	4.43SerGlu: 4.43 ± 0.073	3.64SerPhe: 3.64 ± 0.068	4.903SerGly: 4.903 ± 0.089	1.049SerHis: 1.049 ± 0.036	4.385SerIle: 4.385 ± 0.073	4.741SerLys: 4.741 ± 0.075	5.55SerLeu: 5.55 ± 0.086	1.428SerMet: 1.428 ± 0.047	3.419SerAsn: 3.419 ± 0.069	2.248SerPro: 2.248 ± 0.062	2.361SerGln: 2.361 ± 0.05	2.2SerArg: 2.2 ± 0.053	3.976SerSer: 3.976 ± 0.093	3.381SerThr: 3.381 ± 0.07	4.071SerVal: 4.071 ± 0.081	0.725SerTrp: 0.725 ± 0.033	2.428SerTyr: 2.428 ± 0.061	0.0SerXaa: 0.0 ± 0.0
Thr	3.95ThrAla: 3.95 ± 0.087	0.329ThrCys: 0.329 ± 0.021	3.127ThrAsp: 3.127 ± 0.061	3.656ThrGlu: 3.656 ± 0.071	3.012ThrPhe: 3.012 ± 0.061	3.949ThrGly: 3.949 ± 0.087	0.879ThrHis: 0.879 ± 0.034	4.04ThrIle: 4.04 ± 0.072	3.871ThrLys: 3.871 ± 0.069	4.913ThrLeu: 4.913 ± 0.076	1.076ThrMet: 1.076 ± 0.04	2.961ThrAsn: 2.961 ± 0.08	2.308ThrPro: 2.308 ± 0.056	1.8ThrGln: 1.8 ± 0.051	1.526ThrArg: 1.526 ± 0.047	3.306ThrSer: 3.306 ± 0.075	3.025ThrThr: 3.025 ± 0.096	3.559ThrVal: 3.559 ± 0.078	0.529ThrTrp: 0.529 ± 0.03	2.073ThrTyr: 2.073 ± 0.067	0.0ThrXaa: 0.0 ± 0.0
Val	4.1ValAla: 4.1 ± 0.07	0.496ValCys: 0.496 ± 0.026	3.217ValAsp: 3.217 ± 0.061	3.987ValGlu: 3.987 ± 0.073	3.487ValPhe: 3.487 ± 0.068	3.795ValGly: 3.795 ± 0.08	0.916ValHis: 0.916 ± 0.035	4.444ValIle: 4.444 ± 0.087	4.713ValLys: 4.713 ± 0.064	5.655ValLeu: 5.655 ± 0.084	1.515ValMet: 1.515 ± 0.037	3.451ValAsn: 3.451 ± 0.074	2.296ValPro: 2.296 ± 0.059	2.016ValGln: 2.016 ± 0.049	2.1ValArg: 2.1 ± 0.052	4.3ValSer: 4.3 ± 0.068	3.267ValThr: 3.267 ± 0.078	3.842ValVal: 3.842 ± 0.078	0.628ValTrp: 0.628 ± 0.024	2.332ValTyr: 2.332 ± 0.06	0.0ValXaa: 0.0 ± 0.0
Trp	0.594TrpAla: 0.594 ± 0.031	0.107TrpCys: 0.107 ± 0.012	0.57TrpAsp: 0.57 ± 0.027	0.667TrpGlu: 0.667 ± 0.026	0.566TrpPhe: 0.566 ± 0.027	0.624TrpGly: 0.624 ± 0.03	0.173TrpHis: 0.173 ± 0.015	0.789TrpIle: 0.789 ± 0.033	0.932TrpLys: 0.932 ± 0.03	0.915TrpLeu: 0.915 ± 0.033	0.313TrpMet: 0.313 ± 0.02	0.772TrpAsn: 0.772 ± 0.032	0.168TrpPro: 0.168 ± 0.014	0.391TrpGln: 0.391 ± 0.02	0.38TrpArg: 0.38 ± 0.021	0.599TrpSer: 0.599 ± 0.027	0.537TrpThr: 0.537 ± 0.025	0.58TrpVal: 0.58 ± 0.028	0.122TrpTrp: 0.122 ± 0.013	0.385TrpTyr: 0.385 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.313TyrAla: 2.313 ± 0.048	0.341TyrCys: 0.341 ± 0.022	2.244TyrAsp: 2.244 ± 0.054	2.314TyrGlu: 2.314 ± 0.049	2.72TyrPhe: 2.72 ± 0.072	2.609TyrGly: 2.609 ± 0.06	0.841TyrHis: 0.841 ± 0.033	2.48TyrIle: 2.48 ± 0.061	2.588TyrLys: 2.588 ± 0.051	3.783TyrLeu: 3.783 ± 0.071	0.711TyrMet: 0.711 ± 0.03	2.191TyrAsn: 2.191 ± 0.061	1.519TyrPro: 1.519 ± 0.039	1.683TyrGln: 1.683 ± 0.045	1.743TyrArg: 1.743 ± 0.046	2.71TyrSer: 2.71 ± 0.066	2.033TyrThr: 2.033 ± 0.052	2.065TyrVal: 2.065 ± 0.052	0.465TyrTrp: 0.465 ± 0.025	1.866TyrTyr: 1.866 ± 0.053	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2784 proteins (869067 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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