Amino acid dipepetide frequency for Pomona leaf-nosed bat associated polyomavirus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
17.032AlaAla: 17.032 ± 7.729
0.0AlaCys: 0.0 ± 0.0
6.691AlaAsp: 6.691 ± 1.606
6.083AlaGlu: 6.083 ± 3.438
2.433AlaPhe: 2.433 ± 1.202
8.516AlaGly: 8.516 ± 4.887
1.825AlaHis: 1.825 ± 1.355
3.041AlaIle: 3.041 ± 0.876
4.258AlaLys: 4.258 ± 1.334
9.124AlaLeu: 9.124 ± 1.465
1.217AlaMet: 1.217 ± 1.21
2.433AlaAsn: 2.433 ± 1.111
4.258AlaPro: 4.258 ± 1.661
2.433AlaGln: 2.433 ± 0.903
4.866AlaArg: 4.866 ± 2.529
5.474AlaSer: 5.474 ± 1.169
4.866AlaThr: 4.866 ± 2.069
4.258AlaVal: 4.258 ± 1.426
2.433AlaTrp: 2.433 ± 2.442
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.608CysAla: 0.608 ± 0.452
0.608CysCys: 0.608 ± 0.452
0.608CysAsp: 0.608 ± 0.601
0.0CysGlu: 0.0 ± 0.0
1.217CysPhe: 1.217 ± 0.556
1.825CysGly: 1.825 ± 1.756
0.0CysHis: 0.0 ± 0.0
0.608CysIle: 0.608 ± 0.452
0.608CysLys: 0.608 ± 0.452
0.608CysLeu: 0.608 ± 0.452
0.0CysMet: 0.0 ± 0.0
0.608CysAsn: 0.608 ± 0.452
1.217CysPro: 1.217 ± 1.348
0.0CysGln: 0.0 ± 0.0
0.608CysArg: 0.608 ± 0.452
1.217CysSer: 1.217 ± 0.556
1.217CysThr: 1.217 ± 0.556
1.217CysVal: 1.217 ± 0.903
0.0CysTrp: 0.0 ± 0.0
0.608CysTyr: 0.608 ± 0.601
0.0CysXaa: 0.0 ± 0.0
Asp
2.433AspAla: 2.433 ± 1.264
1.825AspCys: 1.825 ± 1.302
1.217AspAsp: 1.217 ± 0.903
1.217AspGlu: 1.217 ± 0.666
1.217AspPhe: 1.217 ± 0.556
2.433AspGly: 2.433 ± 0.944
1.217AspHis: 1.217 ± 0.903
2.433AspIle: 2.433 ± 1.395
1.825AspLys: 1.825 ± 0.794
7.908AspLeu: 7.908 ± 0.844
2.433AspMet: 2.433 ± 1.202
1.217AspAsn: 1.217 ± 0.556
5.474AspPro: 5.474 ± 2.8
3.041AspGln: 3.041 ± 0.676
1.217AspArg: 1.217 ± 0.903
5.474AspSer: 5.474 ± 1.195
2.433AspThr: 2.433 ± 0.944
1.217AspVal: 1.217 ± 0.903
0.0AspTrp: 0.0 ± 0.0
0.608AspTyr: 0.608 ± 0.601
0.0AspXaa: 0.0 ± 0.0
Glu
5.474GluAla: 5.474 ± 3.079
1.217GluCys: 1.217 ± 0.556
3.041GluAsp: 3.041 ± 1.226
9.124GluGlu: 9.124 ± 3.084
3.65GluPhe: 3.65 ± 2.709
5.474GluGly: 5.474 ± 2.97
0.608GluHis: 0.608 ± 0.601
2.433GluIle: 2.433 ± 0.935
2.433GluLys: 2.433 ± 2.42
5.474GluLeu: 5.474 ± 1.643
3.041GluMet: 3.041 ± 1.226
3.65GluAsn: 3.65 ± 1.998
2.433GluPro: 2.433 ± 0.944
3.65GluGln: 3.65 ± 1.416
2.433GluArg: 2.433 ± 0.944
1.825GluSer: 1.825 ± 0.794
3.041GluThr: 3.041 ± 1.028
1.217GluVal: 1.217 ± 1.203
0.608GluTrp: 0.608 ± 1.281
1.825GluTyr: 1.825 ± 0.794
0.0GluXaa: 0.0 ± 0.0
Phe
2.433PheAla: 2.433 ± 1.194
0.0PheCys: 0.0 ± 0.0
3.041PheAsp: 3.041 ± 1.226
1.825PheGlu: 1.825 ± 0.794
0.608PhePhe: 0.608 ± 0.452
2.433PheGly: 2.433 ± 0.581
1.217PheHis: 1.217 ± 0.472
1.825PheIle: 1.825 ± 1.355
2.433PheLys: 2.433 ± 1.194
6.083PheLeu: 6.083 ± 1.893
3.041PheMet: 3.041 ± 0.947
1.825PheAsn: 1.825 ± 0.983
3.65PhePro: 3.65 ± 1.034
1.217PheGln: 1.217 ± 1.203
3.65PheArg: 3.65 ± 0.933
2.433PheSer: 2.433 ± 1.202
1.825PheThr: 1.825 ± 0.815
1.217PheVal: 1.217 ± 0.556
0.0PheTrp: 0.0 ± 0.0
0.608PheTyr: 0.608 ± 0.452
0.0PheXaa: 0.0 ± 0.0
Gly
7.908GlyAla: 7.908 ± 2.626
1.825GlyCys: 1.825 ± 1.099
3.041GlyAsp: 3.041 ± 0.827
4.258GlyGlu: 4.258 ± 2.039
4.258GlyPhe: 4.258 ± 1.255
6.083GlyGly: 6.083 ± 1.498
2.433GlyHis: 2.433 ± 0.776
3.65GlyIle: 3.65 ± 1.101
4.258GlyLys: 4.258 ± 1.968
6.691GlyLeu: 6.691 ± 2.212
3.65GlyMet: 3.65 ± 0.902
3.041GlyAsn: 3.041 ± 0.827
5.474GlyPro: 5.474 ± 1.719
4.866GlyGln: 4.866 ± 3.909
1.217GlyArg: 1.217 ± 0.944
10.949GlySer: 10.949 ± 1.64
6.691GlyThr: 6.691 ± 2.193
4.258GlyVal: 4.258 ± 1.083
1.217GlyTrp: 1.217 ± 0.556
1.217GlyTyr: 1.217 ± 0.666
0.0GlyXaa: 0.0 ± 0.0
His
1.825HisAla: 1.825 ± 1.355
0.0HisCys: 0.0 ± 0.0
0.608HisAsp: 0.608 ± 0.452
1.217HisGlu: 1.217 ± 0.556
1.825HisPhe: 1.825 ± 0.794
1.217HisGly: 1.217 ± 0.902
2.433HisHis: 2.433 ± 1.806
0.608HisIle: 0.608 ± 0.452
0.608HisLys: 0.608 ± 0.452
2.433HisLeu: 2.433 ± 1.202
0.0HisMet: 0.0 ± 0.0
0.608HisAsn: 0.608 ± 0.452
0.608HisPro: 0.608 ± 0.452
0.0HisGln: 0.0 ± 0.0
0.608HisArg: 0.608 ± 0.472
0.608HisSer: 0.608 ± 0.472
0.608HisThr: 0.608 ± 0.452
1.217HisVal: 1.217 ± 0.556
0.608HisTrp: 0.608 ± 0.911
0.608HisTyr: 0.608 ± 0.601
0.0HisXaa: 0.0 ± 0.0
Ile
4.258IleAla: 4.258 ± 2.039
0.0IleCys: 0.0 ± 0.0
1.217IleAsp: 1.217 ± 0.9
2.433IleGlu: 2.433 ± 0.944
1.825IlePhe: 1.825 ± 0.815
3.65IleGly: 3.65 ± 1.58
0.0IleHis: 0.0 ± 0.0
0.608IleIle: 0.608 ± 0.452
1.217IleLys: 1.217 ± 0.903
1.217IleLeu: 1.217 ± 1.348
0.608IleMet: 0.608 ± 0.601
0.608IleAsn: 0.608 ± 0.601
3.65IlePro: 3.65 ± 1.034
1.217IleGln: 1.217 ± 0.666
0.608IleArg: 0.608 ± 0.452
1.217IleSer: 1.217 ± 0.903
1.217IleThr: 1.217 ± 0.903
4.258IleVal: 4.258 ± 2.086
0.608IleTrp: 0.608 ± 0.601
0.0IleTyr: 0.0 ± 0.0
0.0IleXaa: 0.0 ± 0.0
Lys
1.825LysAla: 1.825 ± 1.355
0.0LysCys: 0.0 ± 0.0
1.217LysAsp: 1.217 ± 0.903
3.041LysGlu: 3.041 ± 1.611
0.608LysPhe: 0.608 ± 0.452
1.825LysGly: 1.825 ± 0.432
1.825LysHis: 1.825 ± 1.355
1.217LysIle: 1.217 ± 1.203
1.825LysLys: 1.825 ± 1.066
3.041LysLeu: 3.041 ± 1.32
1.217LysMet: 1.217 ± 1.043
2.433LysAsn: 2.433 ± 0.944
1.825LysPro: 1.825 ± 1.302
1.825LysGln: 1.825 ± 1.302
5.474LysArg: 5.474 ± 2.112
2.433LysSer: 2.433 ± 1.111
1.825LysThr: 1.825 ± 0.815
2.433LysVal: 2.433 ± 1.194
1.217LysTrp: 1.217 ± 1.348
2.433LysTyr: 2.433 ± 1.438
0.0LysXaa: 0.0 ± 0.0
Leu
8.516LeuAla: 8.516 ± 2.405
1.217LeuCys: 1.217 ± 0.903
4.866LeuAsp: 4.866 ± 1.657
7.299LeuGlu: 7.299 ± 1.207
2.433LeuPhe: 2.433 ± 1.165
7.299LeuGly: 7.299 ± 4.798
1.825LeuHis: 1.825 ± 0.794
3.65LeuIle: 3.65 ± 1.21
6.083LeuLys: 6.083 ± 1.751
15.207LeuLeu: 15.207 ± 15.206
3.041LeuMet: 3.041 ± 3.583
4.258LeuAsn: 4.258 ± 1.549
7.299LeuPro: 7.299 ± 4.356
4.866LeuGln: 4.866 ± 0.542
9.124LeuArg: 9.124 ± 5.182
7.299LeuSer: 7.299 ± 1.151
5.474LeuThr: 5.474 ± 1.755
6.691LeuVal: 6.691 ± 4.251
1.217LeuTrp: 1.217 ± 0.472
2.433LeuTyr: 2.433 ± 1.332
0.0LeuXaa: 0.0 ± 0.0
Met
1.825MetAla: 1.825 ± 0.794
0.608MetCys: 0.608 ± 0.601
1.825MetAsp: 1.825 ± 0.794
3.65MetGlu: 3.65 ± 0.968
1.217MetPhe: 1.217 ± 0.903
3.041MetGly: 3.041 ± 0.676
0.0MetHis: 0.0 ± 0.0
0.0MetIle: 0.0 ± 0.0
0.0MetLys: 0.0 ± 0.0
4.866MetLeu: 4.866 ± 1.982
0.0MetMet: 0.0 ± 0.0
0.608MetAsn: 0.608 ± 0.452
2.433MetPro: 2.433 ± 1.111
0.608MetGln: 0.608 ± 0.601
1.825MetArg: 1.825 ± 2.01
0.608MetSer: 0.608 ± 0.601
2.433MetThr: 2.433 ± 1.128
0.0MetVal: 0.0 ± 0.0
0.0MetTrp: 0.0 ± 0.0
0.608MetTyr: 0.608 ± 0.472
0.0MetXaa: 0.0 ± 0.0
Asn
3.65AsnAla: 3.65 ± 0.901
0.608AsnCys: 0.608 ± 0.601
1.825AsnAsp: 1.825 ± 0.829
0.608AsnGlu: 0.608 ± 0.452
1.825AsnPhe: 1.825 ± 1.355
1.825AsnGly: 1.825 ± 1.066
0.0AsnHis: 0.0 ± 0.0
0.608AsnIle: 0.608 ± 0.472
1.217AsnLys: 1.217 ± 0.556
4.866AsnLeu: 4.866 ± 1.237
0.608AsnMet: 0.608 ± 0.403
1.825AsnAsn: 1.825 ± 0.432
2.433AsnPro: 2.433 ± 2.406
2.433AsnGln: 2.433 ± 1.64
3.041AsnArg: 3.041 ± 0.894
3.041AsnSer: 3.041 ± 1.842
2.433AsnThr: 2.433 ± 0.935
1.217AsnVal: 1.217 ± 0.556
1.825AsnTrp: 1.825 ± 0.986
0.608AsnTyr: 0.608 ± 0.601
0.0AsnXaa: 0.0 ± 0.0
Pro
4.258ProAla: 4.258 ± 2.105
1.217ProCys: 1.217 ± 0.556
6.083ProAsp: 6.083 ± 2.004
4.866ProGlu: 4.866 ± 1.032
1.217ProPhe: 1.217 ± 0.556
6.083ProGly: 6.083 ± 1.661
1.217ProHis: 1.217 ± 0.903
0.608ProIle: 0.608 ± 0.452
1.217ProLys: 1.217 ± 0.556
7.299ProLeu: 7.299 ± 1.941
2.433ProMet: 2.433 ± 1.748
2.433ProAsn: 2.433 ± 0.935
3.041ProPro: 3.041 ± 0.876
0.0ProGln: 0.0 ± 0.0
4.866ProArg: 4.866 ± 3.398
3.65ProSer: 3.65 ± 1.693
3.65ProThr: 3.65 ± 0.864
5.474ProVal: 5.474 ± 3.866
3.041ProTrp: 3.041 ± 1.131
1.217ProTyr: 1.217 ± 0.472
0.0ProXaa: 0.0 ± 0.0
Gln
4.258GlnAla: 4.258 ± 1.426
0.0GlnCys: 0.0 ± 0.0
1.825GlnAsp: 1.825 ± 1.066
2.433GlnGlu: 2.433 ± 1.323
2.433GlnPhe: 2.433 ± 1.111
4.258GlnGly: 4.258 ± 1.046
1.217GlnHis: 1.217 ± 0.556
1.217GlnIle: 1.217 ± 0.944
0.608GlnLys: 0.608 ± 0.452
6.691GlnLeu: 6.691 ± 7.07
0.0GlnMet: 0.0 ± 0.0
1.825GlnAsn: 1.825 ± 1.178
2.433GlnPro: 2.433 ± 1.889
0.608GlnGln: 0.608 ± 0.472
3.041GlnArg: 3.041 ± 0.947
3.041GlnSer: 3.041 ± 1.046
1.825GlnThr: 1.825 ± 1.804
4.258GlnVal: 4.258 ± 2.039
0.0GlnTrp: 0.0 ± 0.0
1.825GlnTyr: 1.825 ± 0.794
0.0GlnXaa: 0.0 ± 0.0
Arg
6.691ArgAla: 6.691 ± 2.097
0.0ArgCys: 0.0 ± 0.0
1.825ArgAsp: 1.825 ± 0.794
4.258ArgGlu: 4.258 ± 1.255
1.217ArgPhe: 1.217 ± 0.903
10.341ArgGly: 10.341 ± 5.552
0.0ArgHis: 0.0 ± 0.0
0.0ArgIle: 0.0 ± 0.0
3.65ArgLys: 3.65 ± 1.151
7.908ArgLeu: 7.908 ± 3.658
0.0ArgMet: 0.0 ± 0.0
1.217ArgAsn: 1.217 ± 0.666
3.041ArgPro: 3.041 ± 0.676
2.433ArgGln: 2.433 ± 1.395
7.299ArgArg: 7.299 ± 3.318
4.258ArgSer: 4.258 ± 1.51
3.041ArgThr: 3.041 ± 2.022
3.041ArgVal: 3.041 ± 1.264
0.608ArgTrp: 0.608 ± 0.452
1.825ArgTyr: 1.825 ± 1.066
0.0ArgXaa: 0.0 ± 0.0
Ser
3.65SerAla: 3.65 ± 1.998
1.217SerCys: 1.217 ± 0.556
2.433SerAsp: 2.433 ± 0.581
4.258SerGlu: 4.258 ± 1.987
2.433SerPhe: 2.433 ± 0.883
8.516SerGly: 8.516 ± 1.28
1.217SerHis: 1.217 ± 0.9
3.041SerIle: 3.041 ± 0.876
1.825SerLys: 1.825 ± 0.815
9.124SerLeu: 9.124 ± 3.16
2.433SerMet: 2.433 ± 1.119
0.0SerAsn: 0.0 ± 0.0
3.65SerPro: 3.65 ± 1.525
3.041SerGln: 3.041 ± 1.028
3.65SerArg: 3.65 ± 0.901
8.516SerSer: 8.516 ± 1.096
6.083SerThr: 6.083 ± 2.272
4.258SerVal: 4.258 ± 0.919
1.217SerTrp: 1.217 ± 0.472
1.825SerTyr: 1.825 ± 0.829
0.0SerXaa: 0.0 ± 0.0
Thr
2.433ThrAla: 2.433 ± 2.055
0.608ThrCys: 0.608 ± 0.452
3.041ThrAsp: 3.041 ± 1.319
1.217ThrGlu: 1.217 ± 0.472
1.825ThrPhe: 1.825 ± 0.794
6.691ThrGly: 6.691 ± 2.372
0.608ThrHis: 0.608 ± 0.452
0.608ThrIle: 0.608 ± 0.452
1.825ThrLys: 1.825 ± 0.794
3.041ThrLeu: 3.041 ± 0.832
0.0ThrMet: 0.0 ± 0.0
3.041ThrAsn: 3.041 ± 1.511
4.866ThrPro: 4.866 ± 1.252
5.474ThrGln: 5.474 ± 1.811
2.433ThrArg: 2.433 ± 1.623
6.083ThrSer: 6.083 ± 2.713
3.65ThrThr: 3.65 ± 2.102
6.083ThrVal: 6.083 ± 1.485
1.217ThrTrp: 1.217 ± 1.348
0.608ThrTyr: 0.608 ± 0.472
0.0ThrXaa: 0.0 ± 0.0
Val
8.516ValAla: 8.516 ± 2.008
0.0ValCys: 0.0 ± 0.0
1.217ValAsp: 1.217 ± 0.472
3.041ValGlu: 3.041 ± 1.028
5.474ValPhe: 5.474 ± 1.36
2.433ValGly: 2.433 ± 0.944
0.608ValHis: 0.608 ± 0.452
3.041ValIle: 3.041 ± 1.264
3.041ValLys: 3.041 ± 2.586
5.474ValLeu: 5.474 ± 2.44
1.825ValMet: 1.825 ± 0.432
2.433ValAsn: 2.433 ± 0.581
4.258ValPro: 4.258 ± 1.082
3.65ValGln: 3.65 ± 0.689
3.041ValArg: 3.041 ± 1.194
1.825ValSer: 1.825 ± 1.066
1.217ValThr: 1.217 ± 0.472
2.433ValVal: 2.433 ± 1.423
0.608ValTrp: 0.608 ± 0.452
3.65ValTyr: 3.65 ± 2.074
0.0ValXaa: 0.0 ± 0.0
Trp
1.217TrpAla: 1.217 ± 0.944
0.608TrpCys: 0.608 ± 0.601
0.608TrpAsp: 0.608 ± 0.452
1.217TrpGlu: 1.217 ± 0.666
1.217TrpPhe: 1.217 ± 0.944
2.433TrpGly: 2.433 ± 0.776
0.0TrpHis: 0.0 ± 0.0
0.608TrpIle: 0.608 ± 0.452
0.0TrpLys: 0.0 ± 0.0
1.217TrpLeu: 1.217 ± 1.348
0.0TrpMet: 0.0 ± 0.0
1.217TrpAsn: 1.217 ± 1.236
1.217TrpPro: 1.217 ± 1.21
1.217TrpGln: 1.217 ± 2.563
0.608TrpArg: 0.608 ± 0.472
1.825TrpSer: 1.825 ± 0.815
0.608TrpThr: 0.608 ± 0.601
0.608TrpVal: 0.608 ± 0.601
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.433TyrAla: 2.433 ± 0.714
1.825TyrCys: 1.825 ± 1.099
0.608TyrAsp: 0.608 ± 0.452
0.608TyrGlu: 0.608 ± 0.472
2.433TyrPhe: 2.433 ± 1.748
0.608TyrGly: 0.608 ± 0.601
0.0TyrHis: 0.0 ± 0.0
0.608TyrIle: 0.608 ± 0.472
1.217TyrLys: 1.217 ± 0.556
1.825TyrLeu: 1.825 ± 0.829
0.0TyrMet: 0.0 ± 0.0
1.217TyrAsn: 1.217 ± 0.556
0.608TyrPro: 0.608 ± 0.452
1.217TyrGln: 1.217 ± 0.472
3.041TyrArg: 3.041 ± 1.719
0.608TyrSer: 0.608 ± 0.452
1.217TyrThr: 1.217 ± 0.556
2.433TyrVal: 2.433 ± 1.64
0.0TyrTrp: 0.0 ± 0.0
1.825TyrTyr: 1.825 ± 0.829
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (1645 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski