Amino acid dipepetide frequency for Salmonella phage Jersey

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
11.183AlaAla: 11.183 ± 1.592
0.889AlaCys: 0.889 ± 0.225
6.073AlaAsp: 6.073 ± 0.582
5.999AlaGlu: 5.999 ± 0.817
4.221AlaPhe: 4.221 ± 0.577
7.258AlaGly: 7.258 ± 0.729
1.851AlaHis: 1.851 ± 0.379
4.592AlaIle: 4.592 ± 0.763
5.702AlaLys: 5.702 ± 0.959
7.184AlaLeu: 7.184 ± 0.785
2.37AlaMet: 2.37 ± 0.415
3.259AlaAsn: 3.259 ± 0.404
3.481AlaPro: 3.481 ± 0.519
3.925AlaGln: 3.925 ± 0.888
4.962AlaArg: 4.962 ± 0.608
6.073AlaSer: 6.073 ± 0.678
5.554AlaThr: 5.554 ± 0.671
7.998AlaVal: 7.998 ± 1.098
1.333AlaTrp: 1.333 ± 0.243
2.962AlaTyr: 2.962 ± 0.438
0.0AlaXaa: 0.0 ± 0.0
Cys
1.037CysAla: 1.037 ± 0.313
0.148CysCys: 0.148 ± 0.109
0.667CysAsp: 0.667 ± 0.23
1.259CysGlu: 1.259 ± 0.316
0.444CysPhe: 0.444 ± 0.195
0.815CysGly: 0.815 ± 0.265
0.296CysHis: 0.296 ± 0.138
0.296CysIle: 0.296 ± 0.16
0.889CysLys: 0.889 ± 0.272
0.592CysLeu: 0.592 ± 0.227
0.222CysMet: 0.222 ± 0.111
0.518CysAsn: 0.518 ± 0.224
0.444CysPro: 0.444 ± 0.181
0.222CysGln: 0.222 ± 0.136
0.741CysArg: 0.741 ± 0.226
0.296CysSer: 0.296 ± 0.161
0.815CysThr: 0.815 ± 0.231
0.815CysVal: 0.815 ± 0.216
0.222CysTrp: 0.222 ± 0.122
0.444CysTyr: 0.444 ± 0.184
0.0CysXaa: 0.0 ± 0.0
Asp
6.739AspAla: 6.739 ± 0.827
0.667AspCys: 0.667 ± 0.205
3.184AspAsp: 3.184 ± 0.51
3.999AspGlu: 3.999 ± 0.596
3.11AspPhe: 3.11 ± 0.419
5.406AspGly: 5.406 ± 0.793
0.741AspHis: 0.741 ± 0.215
3.629AspIle: 3.629 ± 0.458
2.888AspLys: 2.888 ± 0.379
4.592AspLeu: 4.592 ± 0.575
1.333AspMet: 1.333 ± 0.268
3.481AspAsn: 3.481 ± 0.439
1.777AspPro: 1.777 ± 0.38
0.592AspGln: 0.592 ± 0.205
2.666AspArg: 2.666 ± 0.434
3.184AspSer: 3.184 ± 0.451
3.999AspThr: 3.999 ± 0.444
4.147AspVal: 4.147 ± 0.543
0.667AspTrp: 0.667 ± 0.214
2.0AspTyr: 2.0 ± 0.393
0.0AspXaa: 0.0 ± 0.0
Glu
5.999GluAla: 5.999 ± 0.859
0.444GluCys: 0.444 ± 0.212
3.629GluAsp: 3.629 ± 0.56
5.11GluGlu: 5.11 ± 0.974
2.37GluPhe: 2.37 ± 0.504
4.74GluGly: 4.74 ± 0.651
0.963GluHis: 0.963 ± 0.248
3.851GluIle: 3.851 ± 0.482
4.962GluLys: 4.962 ± 0.631
6.147GluLeu: 6.147 ± 0.709
2.74GluMet: 2.74 ± 0.374
2.666GluAsn: 2.666 ± 0.425
1.851GluPro: 1.851 ± 0.526
2.888GluGln: 2.888 ± 0.58
3.851GluArg: 3.851 ± 0.53
3.11GluSer: 3.11 ± 0.414
4.073GluThr: 4.073 ± 0.574
3.925GluVal: 3.925 ± 0.447
1.333GluTrp: 1.333 ± 0.315
2.148GluTyr: 2.148 ± 0.475
0.0GluXaa: 0.0 ± 0.0
Phe
2.666PheAla: 2.666 ± 0.403
0.444PheCys: 0.444 ± 0.171
3.259PheAsp: 3.259 ± 0.506
2.814PheGlu: 2.814 ± 0.413
0.667PhePhe: 0.667 ± 0.192
2.962PheGly: 2.962 ± 0.377
0.741PheHis: 0.741 ± 0.246
2.518PheIle: 2.518 ± 0.475
2.0PheLys: 2.0 ± 0.451
1.777PheLeu: 1.777 ± 0.364
0.37PheMet: 0.37 ± 0.162
1.703PheAsn: 1.703 ± 0.366
1.703PhePro: 1.703 ± 0.38
1.555PheGln: 1.555 ± 0.316
2.37PheArg: 2.37 ± 0.355
2.666PheSer: 2.666 ± 0.541
3.407PheThr: 3.407 ± 0.579
2.518PheVal: 2.518 ± 0.46
0.667PheTrp: 0.667 ± 0.211
1.185PheTyr: 1.185 ± 0.299
0.0PheXaa: 0.0 ± 0.0
Gly
7.184GlyAla: 7.184 ± 0.724
1.037GlyCys: 1.037 ± 0.215
3.703GlyAsp: 3.703 ± 0.549
5.258GlyGlu: 5.258 ± 0.721
3.925GlyPhe: 3.925 ± 0.526
5.925GlyGly: 5.925 ± 0.751
1.925GlyHis: 1.925 ± 0.466
2.74GlyIle: 2.74 ± 0.406
5.258GlyLys: 5.258 ± 0.543
5.184GlyLeu: 5.184 ± 0.513
2.148GlyMet: 2.148 ± 0.545
3.629GlyAsn: 3.629 ± 0.562
2.074GlyPro: 2.074 ± 0.365
3.036GlyGln: 3.036 ± 0.437
3.999GlyArg: 3.999 ± 0.503
5.036GlySer: 5.036 ± 0.805
3.925GlyThr: 3.925 ± 0.627
6.369GlyVal: 6.369 ± 0.539
0.963GlyTrp: 0.963 ± 0.24
2.888GlyTyr: 2.888 ± 0.467
0.0GlyXaa: 0.0 ± 0.0
His
1.037HisAla: 1.037 ± 0.251
0.296HisCys: 0.296 ± 0.145
0.741HisAsp: 0.741 ± 0.213
1.259HisGlu: 1.259 ± 0.3
0.815HisPhe: 0.815 ± 0.237
0.963HisGly: 0.963 ± 0.324
0.667HisHis: 0.667 ± 0.215
1.407HisIle: 1.407 ± 0.329
1.037HisLys: 1.037 ± 0.303
1.259HisLeu: 1.259 ± 0.342
0.444HisMet: 0.444 ± 0.153
0.37HisAsn: 0.37 ± 0.178
1.111HisPro: 1.111 ± 0.282
0.963HisGln: 0.963 ± 0.36
1.259HisArg: 1.259 ± 0.315
1.185HisSer: 1.185 ± 0.304
0.889HisThr: 0.889 ± 0.298
1.037HisVal: 1.037 ± 0.34
0.074HisTrp: 0.074 ± 0.073
0.667HisTyr: 0.667 ± 0.251
0.0HisXaa: 0.0 ± 0.0
Ile
4.888IleAla: 4.888 ± 0.938
0.889IleCys: 0.889 ± 0.313
3.925IleAsp: 3.925 ± 0.647
2.962IleGlu: 2.962 ± 0.388
1.481IlePhe: 1.481 ± 0.338
2.814IleGly: 2.814 ± 0.36
0.889IleHis: 0.889 ± 0.272
2.74IleIle: 2.74 ± 0.45
3.036IleLys: 3.036 ± 0.452
2.518IleLeu: 2.518 ± 0.455
0.815IleMet: 0.815 ± 0.266
3.036IleAsn: 3.036 ± 0.468
2.518IlePro: 2.518 ± 0.381
1.703IleGln: 1.703 ± 0.378
2.666IleArg: 2.666 ± 0.351
3.629IleSer: 3.629 ± 0.519
4.814IleThr: 4.814 ± 0.606
3.703IleVal: 3.703 ± 0.455
0.815IleTrp: 0.815 ± 0.221
1.259IleTyr: 1.259 ± 0.392
0.0IleXaa: 0.0 ± 0.0
Lys
6.147LysAla: 6.147 ± 0.818
1.037LysCys: 1.037 ± 0.404
3.777LysAsp: 3.777 ± 0.664
4.221LysGlu: 4.221 ± 0.739
2.222LysPhe: 2.222 ± 0.317
4.073LysGly: 4.073 ± 0.444
1.555LysHis: 1.555 ± 0.321
2.148LysIle: 2.148 ± 0.482
2.888LysLys: 2.888 ± 0.466
5.258LysLeu: 5.258 ± 0.756
2.518LysMet: 2.518 ± 0.486
2.0LysAsn: 2.0 ± 0.347
2.296LysPro: 2.296 ± 0.497
2.0LysGln: 2.0 ± 0.365
4.295LysArg: 4.295 ± 0.573
3.259LysSer: 3.259 ± 0.554
3.777LysThr: 3.777 ± 0.435
3.999LysVal: 3.999 ± 0.645
0.889LysTrp: 0.889 ± 0.21
2.888LysTyr: 2.888 ± 0.381
0.0LysXaa: 0.0 ± 0.0
Leu
6.887LeuAla: 6.887 ± 0.633
0.667LeuCys: 0.667 ± 0.193
4.147LeuAsp: 4.147 ± 0.56
5.036LeuGlu: 5.036 ± 0.782
2.296LeuPhe: 2.296 ± 0.364
5.554LeuGly: 5.554 ± 0.569
1.111LeuHis: 1.111 ± 0.302
4.592LeuIle: 4.592 ± 0.601
4.814LeuLys: 4.814 ± 0.555
5.628LeuLeu: 5.628 ± 0.767
1.629LeuMet: 1.629 ± 0.374
3.333LeuAsn: 3.333 ± 0.368
3.777LeuPro: 3.777 ± 0.609
2.592LeuGln: 2.592 ± 0.495
4.962LeuArg: 4.962 ± 0.644
4.592LeuSer: 4.592 ± 0.756
4.666LeuThr: 4.666 ± 0.365
4.592LeuVal: 4.592 ± 0.498
1.259LeuTrp: 1.259 ± 0.329
2.296LeuTyr: 2.296 ± 0.382
0.0LeuXaa: 0.0 ± 0.0
Met
2.592MetAla: 2.592 ± 0.328
0.37MetCys: 0.37 ± 0.145
0.963MetAsp: 0.963 ± 0.275
0.889MetGlu: 0.889 ± 0.203
0.815MetPhe: 0.815 ± 0.235
1.555MetGly: 1.555 ± 0.311
0.37MetHis: 0.37 ± 0.157
1.333MetIle: 1.333 ± 0.332
1.925MetLys: 1.925 ± 0.337
2.296MetLeu: 2.296 ± 0.416
0.518MetMet: 0.518 ± 0.243
0.963MetAsn: 0.963 ± 0.279
1.185MetPro: 1.185 ± 0.327
0.741MetGln: 0.741 ± 0.219
1.555MetArg: 1.555 ± 0.281
2.148MetSer: 2.148 ± 0.373
2.074MetThr: 2.074 ± 0.362
2.074MetVal: 2.074 ± 0.445
0.444MetTrp: 0.444 ± 0.141
0.741MetTyr: 0.741 ± 0.211
0.0MetXaa: 0.0 ± 0.0
Asn
4.369AsnAla: 4.369 ± 0.567
0.592AsnCys: 0.592 ± 0.214
2.148AsnAsp: 2.148 ± 0.308
2.444AsnGlu: 2.444 ± 0.422
1.111AsnPhe: 1.111 ± 0.275
3.925AsnGly: 3.925 ± 0.613
0.741AsnHis: 0.741 ± 0.226
2.666AsnIle: 2.666 ± 0.391
2.148AsnLys: 2.148 ± 0.327
3.184AsnLeu: 3.184 ± 0.349
1.037AsnMet: 1.037 ± 0.326
2.666AsnAsn: 2.666 ± 0.487
2.592AsnPro: 2.592 ± 0.503
1.111AsnGln: 1.111 ± 0.209
2.518AsnArg: 2.518 ± 0.372
2.148AsnSer: 2.148 ± 0.4
2.444AsnThr: 2.444 ± 0.454
3.555AsnVal: 3.555 ± 0.424
0.741AsnTrp: 0.741 ± 0.215
1.407AsnTyr: 1.407 ± 0.338
0.0AsnXaa: 0.0 ± 0.0
Pro
3.333ProAla: 3.333 ± 0.484
0.518ProCys: 0.518 ± 0.189
3.629ProAsp: 3.629 ± 0.536
3.11ProGlu: 3.11 ± 0.467
1.703ProPhe: 1.703 ± 0.36
3.333ProGly: 3.333 ± 0.498
0.444ProHis: 0.444 ± 0.154
1.111ProIle: 1.111 ± 0.293
2.0ProLys: 2.0 ± 0.383
3.184ProLeu: 3.184 ± 0.476
0.889ProMet: 0.889 ± 0.235
1.407ProAsn: 1.407 ± 0.488
1.851ProPro: 1.851 ± 0.412
1.037ProGln: 1.037 ± 0.275
2.222ProArg: 2.222 ± 0.333
2.37ProSer: 2.37 ± 0.436
1.851ProThr: 1.851 ± 0.416
3.703ProVal: 3.703 ± 0.562
0.444ProTrp: 0.444 ± 0.206
1.333ProTyr: 1.333 ± 0.37
0.0ProXaa: 0.0 ± 0.0
Gln
3.703GlnAla: 3.703 ± 0.558
0.222GlnCys: 0.222 ± 0.12
1.629GlnAsp: 1.629 ± 0.306
2.222GlnGlu: 2.222 ± 0.447
1.407GlnPhe: 1.407 ± 0.34
2.074GlnGly: 2.074 ± 0.358
0.667GlnHis: 0.667 ± 0.22
1.925GlnIle: 1.925 ± 0.452
2.666GlnLys: 2.666 ± 0.409
3.11GlnLeu: 3.11 ± 0.494
0.963GlnMet: 0.963 ± 0.229
1.555GlnAsn: 1.555 ± 0.396
1.555GlnPro: 1.555 ± 0.309
2.592GlnGln: 2.592 ± 0.726
1.851GlnArg: 1.851 ± 0.34
1.629GlnSer: 1.629 ± 0.33
2.0GlnThr: 2.0 ± 0.345
2.888GlnVal: 2.888 ± 0.451
0.592GlnTrp: 0.592 ± 0.201
1.555GlnTyr: 1.555 ± 0.261
0.0GlnXaa: 0.0 ± 0.0
Arg
4.369ArgAla: 4.369 ± 0.525
0.444ArgCys: 0.444 ± 0.182
3.036ArgAsp: 3.036 ± 0.435
4.221ArgGlu: 4.221 ± 0.656
1.555ArgPhe: 1.555 ± 0.365
4.073ArgGly: 4.073 ± 0.426
1.185ArgHis: 1.185 ± 0.299
3.629ArgIle: 3.629 ± 0.552
4.295ArgLys: 4.295 ± 0.586
3.999ArgLeu: 3.999 ± 0.474
2.074ArgMet: 2.074 ± 0.34
3.259ArgAsn: 3.259 ± 0.476
2.148ArgPro: 2.148 ± 0.351
2.888ArgGln: 2.888 ± 0.447
4.518ArgArg: 4.518 ± 0.654
2.592ArgSer: 2.592 ± 0.411
2.444ArgThr: 2.444 ± 0.386
4.888ArgVal: 4.888 ± 0.54
0.741ArgTrp: 0.741 ± 0.211
1.629ArgTyr: 1.629 ± 0.401
0.0ArgXaa: 0.0 ± 0.0
Ser
6.665SerAla: 6.665 ± 1.134
0.444SerCys: 0.444 ± 0.218
3.333SerAsp: 3.333 ± 0.479
2.814SerGlu: 2.814 ± 0.442
2.518SerPhe: 2.518 ± 0.401
6.221SerGly: 6.221 ± 0.563
0.592SerHis: 0.592 ± 0.169
2.444SerIle: 2.444 ± 0.467
3.703SerLys: 3.703 ± 0.504
5.036SerLeu: 5.036 ± 0.608
1.259SerMet: 1.259 ± 0.251
2.74SerAsn: 2.74 ± 0.386
1.925SerPro: 1.925 ± 0.418
2.592SerGln: 2.592 ± 0.372
3.407SerArg: 3.407 ± 0.424
2.518SerSer: 2.518 ± 0.544
3.925SerThr: 3.925 ± 0.589
4.814SerVal: 4.814 ± 0.688
0.592SerTrp: 0.592 ± 0.22
2.074SerTyr: 2.074 ± 0.383
0.0SerXaa: 0.0 ± 0.0
Thr
6.295ThrAla: 6.295 ± 0.755
0.592ThrCys: 0.592 ± 0.218
3.851ThrAsp: 3.851 ± 0.485
4.592ThrGlu: 4.592 ± 0.497
3.259ThrPhe: 3.259 ± 0.472
6.073ThrGly: 6.073 ± 0.854
0.815ThrHis: 0.815 ± 0.244
2.888ThrIle: 2.888 ± 0.474
3.11ThrLys: 3.11 ± 0.437
4.814ThrLeu: 4.814 ± 0.631
1.037ThrMet: 1.037 ± 0.277
1.851ThrAsn: 1.851 ± 0.28
3.333ThrPro: 3.333 ± 0.491
2.074ThrGln: 2.074 ± 0.383
2.962ThrArg: 2.962 ± 0.402
4.666ThrSer: 4.666 ± 0.625
3.11ThrThr: 3.11 ± 0.444
4.073ThrVal: 4.073 ± 0.632
0.963ThrTrp: 0.963 ± 0.249
2.37ThrTyr: 2.37 ± 0.399
0.0ThrXaa: 0.0 ± 0.0
Val
7.11ValAla: 7.11 ± 0.701
0.592ValCys: 0.592 ± 0.21
4.221ValAsp: 4.221 ± 0.52
5.925ValGlu: 5.925 ± 0.604
2.074ValPhe: 2.074 ± 0.435
4.369ValGly: 4.369 ± 0.513
0.667ValHis: 0.667 ± 0.196
4.369ValIle: 4.369 ± 0.627
5.11ValLys: 5.11 ± 0.599
5.11ValLeu: 5.11 ± 0.707
1.407ValMet: 1.407 ± 0.323
3.036ValAsn: 3.036 ± 0.453
2.148ValPro: 2.148 ± 0.55
2.222ValGln: 2.222 ± 0.375
4.147ValArg: 4.147 ± 0.538
5.628ValSer: 5.628 ± 0.751
5.999ValThr: 5.999 ± 0.718
5.406ValVal: 5.406 ± 0.687
0.963ValTrp: 0.963 ± 0.264
3.259ValTyr: 3.259 ± 0.484
0.0ValXaa: 0.0 ± 0.0
Trp
1.407TrpAla: 1.407 ± 0.385
0.148TrpCys: 0.148 ± 0.098
0.741TrpAsp: 0.741 ± 0.195
0.518TrpGlu: 0.518 ± 0.17
0.741TrpPhe: 0.741 ± 0.314
1.111TrpGly: 1.111 ± 0.305
0.444TrpHis: 0.444 ± 0.208
0.518TrpIle: 0.518 ± 0.176
0.592TrpLys: 0.592 ± 0.181
1.703TrpLeu: 1.703 ± 0.372
0.592TrpMet: 0.592 ± 0.189
0.592TrpAsn: 0.592 ± 0.217
0.296TrpPro: 0.296 ± 0.162
0.741TrpGln: 0.741 ± 0.245
0.963TrpArg: 0.963 ± 0.236
0.592TrpSer: 0.592 ± 0.247
0.741TrpThr: 0.741 ± 0.229
1.333TrpVal: 1.333 ± 0.257
0.148TrpTrp: 0.148 ± 0.103
0.222TrpTyr: 0.222 ± 0.115
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.259TyrAla: 3.259 ± 0.483
0.741TyrCys: 0.741 ± 0.218
2.148TyrAsp: 2.148 ± 0.519
2.222TyrGlu: 2.222 ± 0.386
1.259TyrPhe: 1.259 ± 0.289
2.962TyrGly: 2.962 ± 0.453
0.815TyrHis: 0.815 ± 0.184
1.703TyrIle: 1.703 ± 0.294
2.222TyrLys: 2.222 ± 0.494
1.851TyrLeu: 1.851 ± 0.318
1.111TyrMet: 1.111 ± 0.218
1.481TyrAsn: 1.481 ± 0.293
1.407TyrPro: 1.407 ± 0.398
1.333TyrGln: 1.333 ± 0.323
2.074TyrArg: 2.074 ± 0.404
2.296TyrSer: 2.296 ± 0.405
2.222TyrThr: 2.222 ± 0.431
1.925TyrVal: 1.925 ± 0.379
0.296TyrTrp: 0.296 ± 0.162
0.963TyrTyr: 0.963 ± 0.236
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 69 proteins (13504 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski