Amino acid dipepetide frequency for Chickpea chlorotic stunt virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.792AlaAla: 5.792 ± 0.793
1.931AlaCys: 1.931 ± 0.842
2.896AlaAsp: 2.896 ± 0.891
4.505AlaGlu: 4.505 ± 0.729
2.896AlaPhe: 2.896 ± 0.706
4.505AlaGly: 4.505 ± 0.963
0.644AlaHis: 0.644 ± 0.286
3.539AlaIle: 3.539 ± 0.974
2.896AlaLys: 2.896 ± 1.086
4.505AlaLeu: 4.505 ± 1.1
0.322AlaMet: 0.322 ± 0.231
1.931AlaAsn: 1.931 ± 0.383
2.896AlaPro: 2.896 ± 0.95
3.539AlaGln: 3.539 ± 1.025
5.148AlaArg: 5.148 ± 1.148
5.47AlaSer: 5.47 ± 0.874
2.252AlaThr: 2.252 ± 0.646
1.931AlaVal: 1.931 ± 0.665
0.322AlaTrp: 0.322 ± 0.231
3.539AlaTyr: 3.539 ± 0.947
0.0AlaXaa: 0.0 ± 0.0
Cys
0.965CysAla: 0.965 ± 0.421
0.0CysCys: 0.0 ± 0.0
0.965CysAsp: 0.965 ± 0.524
0.322CysGlu: 0.322 ± 0.302
1.609CysPhe: 1.609 ± 0.583
1.287CysGly: 1.287 ± 0.616
0.0CysHis: 0.0 ± 0.0
0.965CysIle: 0.965 ± 0.421
1.287CysLys: 1.287 ± 0.935
2.252CysLeu: 2.252 ± 1.605
0.0CysMet: 0.0 ± 0.0
0.644CysAsn: 0.644 ± 0.286
1.609CysPro: 1.609 ± 0.576
0.644CysGln: 0.644 ± 0.427
0.0CysArg: 0.0 ± 0.0
2.896CysSer: 2.896 ± 1.263
1.609CysThr: 1.609 ± 0.274
0.644CysVal: 0.644 ± 0.286
0.322CysTrp: 0.322 ± 0.231
0.644CysTyr: 0.644 ± 0.85
0.0CysXaa: 0.0 ± 0.0
Asp
3.861AspAla: 3.861 ± 1.144
1.931AspCys: 1.931 ± 0.401
3.539AspAsp: 3.539 ± 1.117
5.148AspGlu: 5.148 ± 0.578
0.644AspPhe: 0.644 ± 0.286
2.896AspGly: 2.896 ± 0.68
0.322AspHis: 0.322 ± 0.425
1.609AspIle: 1.609 ± 0.274
0.965AspLys: 0.965 ± 0.633
4.826AspLeu: 4.826 ± 1.339
1.609AspMet: 1.609 ± 0.682
2.574AspAsn: 2.574 ± 1.326
2.252AspPro: 2.252 ± 0.787
1.931AspGln: 1.931 ± 0.682
0.965AspArg: 0.965 ± 0.402
3.218AspSer: 3.218 ± 1.471
1.931AspThr: 1.931 ± 0.487
1.931AspVal: 1.931 ± 1.461
1.287AspTrp: 1.287 ± 0.597
0.965AspTyr: 0.965 ± 0.413
0.0AspXaa: 0.0 ± 0.0
Glu
6.113GluAla: 6.113 ± 0.616
1.609GluCys: 1.609 ± 0.462
6.435GluAsp: 6.435 ± 1.841
6.757GluGlu: 6.757 ± 1.469
4.505GluPhe: 4.505 ± 0.637
4.183GluGly: 4.183 ± 1.116
0.0GluHis: 0.0 ± 0.0
3.218GluIle: 3.218 ± 1.044
3.539GluLys: 3.539 ± 1.163
5.792GluLeu: 5.792 ± 1.214
1.931GluMet: 1.931 ± 0.787
2.574GluAsn: 2.574 ± 0.723
1.931GluPro: 1.931 ± 0.665
1.931GluGln: 1.931 ± 0.672
3.218GluArg: 3.218 ± 0.694
4.505GluSer: 4.505 ± 0.908
3.861GluThr: 3.861 ± 1.062
2.574GluVal: 2.574 ± 1.067
1.609GluTrp: 1.609 ± 0.489
1.931GluTyr: 1.931 ± 0.892
0.0GluXaa: 0.0 ± 0.0
Phe
1.287PheAla: 1.287 ± 0.439
2.896PheCys: 2.896 ± 1.013
2.252PheAsp: 2.252 ± 0.396
2.574PheGlu: 2.574 ± 0.82
2.252PhePhe: 2.252 ± 0.396
4.183PheGly: 4.183 ± 1.174
1.287PheHis: 1.287 ± 0.288
1.609PheIle: 1.609 ± 0.865
1.931PheLys: 1.931 ± 0.507
2.252PheLeu: 2.252 ± 0.645
0.322PheMet: 0.322 ± 0.231
0.644PheAsn: 0.644 ± 0.27
0.322PhePro: 0.322 ± 0.425
2.252PheGln: 2.252 ± 0.83
2.574PheArg: 2.574 ± 0.918
5.47PheSer: 5.47 ± 0.678
1.287PheThr: 1.287 ± 0.788
2.574PheVal: 2.574 ± 0.411
0.965PheTrp: 0.965 ± 0.644
1.931PheTyr: 1.931 ± 0.507
0.0PheXaa: 0.0 ± 0.0
Gly
2.574GlyAla: 2.574 ± 0.396
1.287GlyCys: 1.287 ± 0.288
2.574GlyAsp: 2.574 ± 0.953
4.183GlyGlu: 4.183 ± 0.348
4.826GlyPhe: 4.826 ± 1.424
3.861GlyGly: 3.861 ± 1.101
1.287GlyHis: 1.287 ± 0.789
3.539GlyIle: 3.539 ± 1.211
5.148GlyLys: 5.148 ± 1.178
7.4GlyLeu: 7.4 ± 1.594
0.965GlyMet: 0.965 ± 0.421
3.218GlyAsn: 3.218 ± 0.793
2.896GlyPro: 2.896 ± 0.728
1.931GlyGln: 1.931 ± 0.532
5.792GlyArg: 5.792 ± 1.364
10.296GlySer: 10.296 ± 2.66
2.574GlyThr: 2.574 ± 0.411
3.218GlyVal: 3.218 ± 0.314
0.644GlyTrp: 0.644 ± 0.462
2.252GlyTyr: 2.252 ± 0.482
0.0GlyXaa: 0.0 ± 0.0
His
0.644HisAla: 0.644 ± 0.45
1.609HisCys: 1.609 ± 0.303
0.965HisAsp: 0.965 ± 0.421
0.965HisGlu: 0.965 ± 0.366
0.965HisPhe: 0.965 ± 0.413
0.322HisGly: 0.322 ± 0.425
0.965HisHis: 0.965 ± 1.275
0.322HisIle: 0.322 ± 0.231
1.609HisLys: 1.609 ± 0.682
2.896HisLeu: 2.896 ± 0.553
0.644HisMet: 0.644 ± 0.286
0.644HisAsn: 0.644 ± 0.454
1.609HisPro: 1.609 ± 0.812
0.322HisGln: 0.322 ± 0.425
0.965HisArg: 0.965 ± 0.396
1.609HisSer: 1.609 ± 0.784
1.287HisThr: 1.287 ± 0.572
1.609HisVal: 1.609 ± 0.462
0.0HisTrp: 0.0 ± 0.0
0.0HisTyr: 0.0 ± 0.0
0.0HisXaa: 0.0 ± 0.0
Ile
3.861IleAla: 3.861 ± 0.671
0.322IleCys: 0.322 ± 0.425
1.931IleAsp: 1.931 ± 0.665
1.287IleGlu: 1.287 ± 0.651
2.896IlePhe: 2.896 ± 1.238
1.931IleGly: 1.931 ± 0.668
0.0IleHis: 0.0 ± 0.0
1.931IleIle: 1.931 ± 0.35
2.896IleLys: 2.896 ± 1.042
4.505IleLeu: 4.505 ± 0.715
1.609IleMet: 1.609 ± 0.682
3.539IleAsn: 3.539 ± 1.481
3.861IlePro: 3.861 ± 0.675
1.287IleGln: 1.287 ± 0.788
1.287IleArg: 1.287 ± 0.478
2.574IleSer: 2.574 ± 1.289
5.148IleThr: 5.148 ± 0.847
3.539IleVal: 3.539 ± 1.253
1.609IleTrp: 1.609 ± 0.57
1.287IleTyr: 1.287 ± 0.288
0.0IleXaa: 0.0 ± 0.0
Lys
1.931LysAla: 1.931 ± 0.48
0.965LysCys: 0.965 ± 0.366
1.931LysAsp: 1.931 ± 0.773
3.861LysGlu: 3.861 ± 1.414
2.896LysPhe: 2.896 ± 1.267
7.4LysGly: 7.4 ± 1.282
1.931LysHis: 1.931 ± 0.842
4.826LysIle: 4.826 ± 0.678
2.252LysLys: 2.252 ± 0.984
7.079LysLeu: 7.079 ± 0.684
1.931LysMet: 1.931 ± 0.693
1.931LysAsn: 1.931 ± 1.09
2.896LysPro: 2.896 ± 0.626
1.931LysGln: 1.931 ± 0.507
1.931LysArg: 1.931 ± 0.842
5.792LysSer: 5.792 ± 0.86
4.183LysThr: 4.183 ± 1.422
3.539LysVal: 3.539 ± 1.658
0.644LysTrp: 0.644 ± 0.27
1.287LysTyr: 1.287 ± 0.482
0.322LysXaa: 0.322 ± 0.302
Leu
7.079LeuAla: 7.079 ± 1.706
0.644LeuCys: 0.644 ± 0.397
1.931LeuAsp: 1.931 ± 0.682
9.009LeuGlu: 9.009 ± 0.791
2.896LeuPhe: 2.896 ± 1.653
4.183LeuGly: 4.183 ± 1.523
2.574LeuHis: 2.574 ± 0.647
4.505LeuIle: 4.505 ± 0.54
3.218LeuLys: 3.218 ± 0.924
8.044LeuLeu: 8.044 ± 2.938
0.322LeuMet: 0.322 ± 0.836
2.896LeuAsn: 2.896 ± 0.973
4.505LeuPro: 4.505 ± 0.465
3.218LeuGln: 3.218 ± 0.985
5.47LeuArg: 5.47 ± 0.563
8.366LeuSer: 8.366 ± 0.807
6.113LeuThr: 6.113 ± 1.408
6.757LeuVal: 6.757 ± 1.554
1.931LeuTrp: 1.931 ± 0.653
2.896LeuTyr: 2.896 ± 0.535
0.0LeuXaa: 0.0 ± 0.0
Met
2.574MetAla: 2.574 ± 0.665
0.644MetCys: 0.644 ± 0.27
0.644MetAsp: 0.644 ± 0.601
2.896MetGlu: 2.896 ± 0.706
0.0MetPhe: 0.0 ± 0.0
0.965MetGly: 0.965 ± 0.694
0.0MetHis: 0.0 ± 0.0
0.965MetIle: 0.965 ± 0.244
1.609MetLys: 1.609 ± 0.437
1.609MetLeu: 1.609 ± 0.682
0.0MetMet: 0.0 ± 0.0
1.609MetAsn: 1.609 ± 0.702
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
0.0MetArg: 0.0 ± 0.0
1.931MetSer: 1.931 ± 1.051
0.965MetThr: 0.965 ± 0.244
1.609MetVal: 1.609 ± 0.303
0.322MetTrp: 0.322 ± 0.302
0.644MetTyr: 0.644 ± 0.286
0.0MetXaa: 0.0 ± 0.0
Asn
0.644AsnAla: 0.644 ± 0.286
0.644AsnCys: 0.644 ± 0.45
2.252AsnAsp: 2.252 ± 0.481
1.931AsnGlu: 1.931 ± 0.61
2.252AsnPhe: 2.252 ± 1.242
4.183AsnGly: 4.183 ± 1.554
0.322AsnHis: 0.322 ± 0.231
1.287AsnIle: 1.287 ± 0.397
4.183AsnLys: 4.183 ± 0.559
3.539AsnLeu: 3.539 ± 0.984
1.287AsnMet: 1.287 ± 0.517
4.183AsnAsn: 4.183 ± 0.955
2.574AsnPro: 2.574 ± 1.075
0.965AsnGln: 0.965 ± 0.906
3.861AsnArg: 3.861 ± 0.589
3.218AsnSer: 3.218 ± 0.394
2.896AsnThr: 2.896 ± 0.852
2.252AsnVal: 2.252 ± 0.396
1.609AsnTrp: 1.609 ± 0.437
3.539AsnTyr: 3.539 ± 1.065
0.0AsnXaa: 0.0 ± 0.0
Pro
3.218ProAla: 3.218 ± 0.851
0.644ProCys: 0.644 ± 0.454
0.965ProAsp: 0.965 ± 0.524
3.539ProGlu: 3.539 ± 0.876
0.322ProPhe: 0.322 ± 0.425
3.861ProGly: 3.861 ± 0.727
2.252ProHis: 2.252 ± 0.462
0.965ProIle: 0.965 ± 0.402
4.505ProLys: 4.505 ± 0.824
3.218ProLeu: 3.218 ± 1.256
0.322ProMet: 0.322 ± 0.302
1.609ProAsn: 1.609 ± 0.77
6.435ProPro: 6.435 ± 2.949
4.183ProGln: 4.183 ± 1.101
2.252ProArg: 2.252 ± 0.655
3.861ProSer: 3.861 ± 1.371
2.574ProThr: 2.574 ± 1.197
3.218ProVal: 3.218 ± 0.827
0.644ProTrp: 0.644 ± 0.454
1.931ProTyr: 1.931 ± 0.507
0.0ProXaa: 0.0 ± 0.0
Gln
1.287GlnAla: 1.287 ± 0.463
0.0GlnCys: 0.0 ± 0.0
1.287GlnAsp: 1.287 ± 0.485
3.218GlnGlu: 3.218 ± 0.845
1.609GlnPhe: 1.609 ± 0.576
1.931GlnGly: 1.931 ± 0.653
1.287GlnHis: 1.287 ± 0.616
0.644GlnIle: 0.644 ± 0.462
3.218GlnLys: 3.218 ± 1.431
3.218GlnLeu: 3.218 ± 1.259
0.322GlnMet: 0.322 ± 0.302
3.218GlnAsn: 3.218 ± 0.851
1.931GlnPro: 1.931 ± 0.85
0.644GlnGln: 0.644 ± 0.27
3.539GlnArg: 3.539 ± 1.064
3.218GlnSer: 3.218 ± 1.107
2.252GlnThr: 2.252 ± 0.655
2.252GlnVal: 2.252 ± 0.617
0.644GlnTrp: 0.644 ± 0.789
1.931GlnTyr: 1.931 ± 0.665
0.0GlnXaa: 0.0 ± 0.0
Arg
3.539ArgAla: 3.539 ± 1.763
0.322ArgCys: 0.322 ± 0.425
0.322ArgAsp: 0.322 ± 0.425
1.609ArgGlu: 1.609 ± 0.615
1.609ArgPhe: 1.609 ± 0.421
5.792ArgGly: 5.792 ± 1.565
1.287ArgHis: 1.287 ± 0.64
4.183ArgIle: 4.183 ± 0.561
3.218ArgLys: 3.218 ± 0.608
6.113ArgLeu: 6.113 ± 1.042
0.965ArgMet: 0.965 ± 0.83
5.148ArgAsn: 5.148 ± 1.707
1.609ArgPro: 1.609 ± 0.583
1.287ArgGln: 1.287 ± 0.551
12.227ArgArg: 12.227 ± 5.044
5.148ArgSer: 5.148 ± 0.997
2.252ArgThr: 2.252 ± 0.724
3.539ArgVal: 3.539 ± 1.391
1.931ArgTrp: 1.931 ± 0.842
0.965ArgTyr: 0.965 ± 0.845
0.0ArgXaa: 0.0 ± 0.0
Ser
4.183SerAla: 4.183 ± 1.145
1.287SerCys: 1.287 ± 0.572
5.148SerAsp: 5.148 ± 0.92
5.792SerGlu: 5.792 ± 1.012
3.861SerPhe: 3.861 ± 1.17
9.009SerGly: 9.009 ± 1.648
0.965SerHis: 0.965 ± 0.576
5.47SerIle: 5.47 ± 0.656
6.435SerLys: 6.435 ± 1.582
7.722SerLeu: 7.722 ± 1.688
2.574SerMet: 2.574 ± 0.626
4.826SerAsn: 4.826 ± 0.935
5.792SerPro: 5.792 ± 1.664
2.896SerGln: 2.896 ± 0.763
3.539SerArg: 3.539 ± 1.289
12.227SerSer: 12.227 ± 2.393
5.47SerThr: 5.47 ± 1.346
3.861SerVal: 3.861 ± 1.073
3.218SerTrp: 3.218 ± 0.653
2.574SerTyr: 2.574 ± 0.411
0.0SerXaa: 0.0 ± 0.0
Thr
5.47ThrAla: 5.47 ± 0.987
1.287ThrCys: 1.287 ± 0.288
2.252ThrAsp: 2.252 ± 0.617
2.574ThrGlu: 2.574 ± 0.673
1.931ThrPhe: 1.931 ± 1.282
2.574ThrGly: 2.574 ± 0.951
1.287ThrHis: 1.287 ± 0.485
1.931ThrIle: 1.931 ± 0.59
2.896ThrLys: 2.896 ± 0.635
1.931ThrLeu: 1.931 ± 0.313
0.965ThrMet: 0.965 ± 0.407
1.287ThrAsn: 1.287 ± 0.485
3.218ThrPro: 3.218 ± 0.801
2.896ThrGln: 2.896 ± 0.928
2.896ThrArg: 2.896 ± 1.217
9.653ThrSer: 9.653 ± 1.345
3.539ThrThr: 3.539 ± 0.911
5.47ThrVal: 5.47 ± 0.885
0.0ThrTrp: 0.0 ± 0.0
0.322ThrTyr: 0.322 ± 0.231
0.0ThrXaa: 0.0 ± 0.0
Val
3.539ValAla: 3.539 ± 1.253
0.0ValCys: 0.0 ± 0.0
2.574ValAsp: 2.574 ± 0.704
4.183ValGlu: 4.183 ± 0.599
1.287ValPhe: 1.287 ± 0.563
4.826ValGly: 4.826 ± 1.072
1.287ValHis: 1.287 ± 0.288
1.931ValIle: 1.931 ± 0.775
5.47ValLys: 5.47 ± 1.286
6.113ValLeu: 6.113 ± 1.822
0.965ValMet: 0.965 ± 0.421
2.574ValAsn: 2.574 ± 0.9
3.861ValPro: 3.861 ± 0.97
3.218ValGln: 3.218 ± 0.583
2.896ValArg: 2.896 ± 0.535
3.539ValSer: 3.539 ± 0.473
1.931ValThr: 1.931 ± 0.507
4.183ValVal: 4.183 ± 2.095
1.609ValTrp: 1.609 ± 0.437
2.896ValTyr: 2.896 ± 0.52
0.0ValXaa: 0.0 ± 0.0
Trp
1.287TrpAla: 1.287 ± 0.572
0.322TrpCys: 0.322 ± 0.231
0.322TrpAsp: 0.322 ± 0.231
1.931TrpGlu: 1.931 ± 0.792
0.0TrpPhe: 0.0 ± 0.0
0.965TrpGly: 0.965 ± 0.524
0.644TrpHis: 0.644 ± 0.427
1.609TrpIle: 1.609 ± 0.437
0.965TrpLys: 0.965 ± 0.244
2.252TrpLeu: 2.252 ± 0.992
0.644TrpMet: 0.644 ± 0.286
0.644TrpAsn: 0.644 ± 0.454
0.322TrpPro: 0.322 ± 0.231
0.644TrpGln: 0.644 ± 0.286
1.609TrpArg: 1.609 ± 0.645
1.931TrpSer: 1.931 ± 1.1
0.965TrpThr: 0.965 ± 0.244
1.931TrpVal: 1.931 ± 0.859
0.0TrpTrp: 0.0 ± 0.0
0.965TrpTyr: 0.965 ± 0.244
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.609TyrAla: 1.609 ± 0.75
0.322TyrCys: 0.322 ± 0.425
3.218TyrAsp: 3.218 ± 0.773
1.931TyrGlu: 1.931 ± 0.75
1.609TyrPhe: 1.609 ± 0.36
1.609TyrGly: 1.609 ± 0.528
1.609TyrHis: 1.609 ± 0.303
2.252TyrIle: 2.252 ± 0.489
3.218TyrLys: 3.218 ± 1.103
1.609TyrLeu: 1.609 ± 0.592
0.965TyrMet: 0.965 ± 0.244
1.931TyrAsn: 1.931 ± 0.418
0.0TyrPro: 0.0 ± 0.0
1.931TyrGln: 1.931 ± 0.653
2.896TyrArg: 2.896 ± 0.512
1.931TyrSer: 1.931 ± 0.383
1.287TyrThr: 1.287 ± 0.468
1.931TyrVal: 1.931 ± 0.35
0.644TyrTrp: 0.644 ± 0.286
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.322XaaVal: 0.322 ± 0.302
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (3109 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski