Amino acid dipepetide frequency for Leptopilina boulardi Toti-like virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
16.155AlaAla: 16.155 ± 5.721
2.423AlaCys: 2.423 ± 0.597
4.847AlaAsp: 4.847 ± 1.195
6.866AlaGlu: 6.866 ± 0.931
2.019AlaPhe: 2.019 ± 0.263
10.097AlaGly: 10.097 ± 1.293
0.808AlaHis: 0.808 ± 0.417
4.039AlaIle: 4.039 ± 0.126
1.212AlaLys: 1.212 ± 0.028
8.078AlaLeu: 8.078 ± 0.401
2.423AlaMet: 2.423 ± 0.055
2.423AlaAsn: 2.423 ± 0.597
3.635AlaPro: 3.635 ± 1.222
2.827AlaGln: 2.827 ± 0.153
6.462AlaArg: 6.462 ± 0.723
3.635AlaSer: 3.635 ± 0.083
2.827AlaThr: 2.827 ± 0.806
6.866AlaVal: 6.866 ± 0.373
2.423AlaTrp: 2.423 ± 1.25
3.231AlaTyr: 3.231 ± 1.014
0.0AlaXaa: 0.0 ± 0.0
Cys
1.212CysAla: 1.212 ± 0.028
0.404CysCys: 0.404 ± 0.208
0.0CysAsp: 0.0 ± 0.0
0.404CysGlu: 0.404 ± 0.444
0.0CysPhe: 0.0 ± 0.0
2.019CysGly: 2.019 ± 0.263
0.404CysHis: 0.404 ± 0.444
0.0CysIle: 0.0 ± 0.0
1.212CysLys: 1.212 ± 0.028
2.019CysLeu: 2.019 ± 0.389
0.0CysMet: 0.0 ± 0.0
0.808CysAsn: 0.808 ± 0.417
1.212CysPro: 1.212 ± 0.028
0.404CysGln: 0.404 ± 0.208
0.808CysArg: 0.808 ± 0.236
2.019CysSer: 2.019 ± 0.389
0.808CysThr: 0.808 ± 0.417
2.423CysVal: 2.423 ± 0.707
0.0CysTrp: 0.0 ± 0.0
1.212CysTyr: 1.212 ± 0.028
0.0CysXaa: 0.0 ± 0.0
Asp
5.654AspAla: 5.654 ± 0.346
0.808AspCys: 0.808 ± 0.236
7.674AspAsp: 7.674 ± 2.0
5.654AspGlu: 5.654 ± 0.346
1.616AspPhe: 1.616 ± 0.472
6.462AspGly: 6.462 ± 0.071
0.404AspHis: 0.404 ± 0.208
1.616AspIle: 1.616 ± 0.181
2.019AspLys: 2.019 ± 0.389
4.039AspLeu: 4.039 ± 0.527
1.212AspMet: 1.212 ± 0.028
1.212AspAsn: 1.212 ± 0.028
4.443AspPro: 4.443 ± 0.986
1.616AspGln: 1.616 ± 0.181
5.654AspArg: 5.654 ± 0.306
3.635AspSer: 3.635 ± 1.222
4.039AspThr: 4.039 ± 0.126
4.443AspVal: 4.443 ± 0.334
1.212AspTrp: 1.212 ± 0.028
1.212AspTyr: 1.212 ± 0.028
0.0AspXaa: 0.0 ± 0.0
Glu
6.462GluAla: 6.462 ± 1.234
1.616GluCys: 1.616 ± 0.181
3.635GluAsp: 3.635 ± 2.04
6.462GluGlu: 6.462 ± 1.375
1.212GluPhe: 1.212 ± 0.68
4.847GluGly: 4.847 ± 1.847
0.808GluHis: 0.808 ± 0.236
1.212GluIle: 1.212 ± 0.68
4.443GluLys: 4.443 ± 0.318
6.058GluLeu: 6.058 ± 0.138
2.019GluMet: 2.019 ± 0.263
0.404GluAsn: 0.404 ± 0.208
2.423GluPro: 2.423 ± 1.25
1.616GluGln: 1.616 ± 0.833
6.462GluArg: 6.462 ± 0.071
4.443GluSer: 4.443 ± 0.334
0.808GluThr: 0.808 ± 0.417
5.654GluVal: 5.654 ± 1.651
2.019GluTrp: 2.019 ± 0.263
1.212GluTyr: 1.212 ± 0.625
0.0GluXaa: 0.0 ± 0.0
Phe
2.827PheAla: 2.827 ± 0.499
1.616PheCys: 1.616 ± 0.181
1.616PheAsp: 1.616 ± 0.472
0.808PheGlu: 0.808 ± 0.417
0.0PhePhe: 0.0 ± 0.0
1.616PheGly: 1.616 ± 0.472
1.212PheHis: 1.212 ± 0.028
0.808PheIle: 0.808 ± 0.417
2.019PheLys: 2.019 ± 0.263
2.019PheLeu: 2.019 ± 2.22
0.404PheMet: 0.404 ± 0.444
0.808PheAsn: 0.808 ± 0.417
1.212PhePro: 1.212 ± 0.625
0.0PheGln: 0.0 ± 0.0
2.019PheArg: 2.019 ± 0.389
1.616PheSer: 1.616 ± 0.833
1.212PheThr: 1.212 ± 0.028
0.808PheVal: 0.808 ± 0.236
0.404PheTrp: 0.404 ± 0.444
0.404PheTyr: 0.404 ± 0.444
0.0PheXaa: 0.0 ± 0.0
Gly
6.058GlyAla: 6.058 ± 1.167
1.212GlyCys: 1.212 ± 1.332
4.443GlyAsp: 4.443 ± 0.318
6.462GlyGlu: 6.462 ± 0.723
3.635GlyPhe: 3.635 ± 1.222
15.751GlyGly: 15.751 ± 2.251
1.616GlyHis: 1.616 ± 0.181
1.616GlyIle: 1.616 ± 0.181
7.27GlyLys: 7.27 ± 2.122
7.674GlyLeu: 7.674 ± 1.262
2.827GlyMet: 2.827 ± 1.911
2.827GlyAsn: 2.827 ± 0.153
5.25GlyPro: 5.25 ± 0.75
1.616GlyGln: 1.616 ± 0.181
7.674GlyArg: 7.674 ± 3.305
6.058GlySer: 6.058 ± 1.167
6.058GlyThr: 6.058 ± 0.138
10.501GlyVal: 10.501 ± 1.108
4.039GlyTrp: 4.039 ± 0.527
3.231GlyTyr: 3.231 ± 0.943
0.0GlyXaa: 0.0 ± 0.0
His
1.212HisAla: 1.212 ± 0.028
0.808HisCys: 0.808 ± 0.236
1.212HisAsp: 1.212 ± 0.028
0.0HisGlu: 0.0 ± 0.0
0.404HisPhe: 0.404 ± 0.444
3.635HisGly: 3.635 ± 0.735
0.404HisHis: 0.404 ± 0.208
0.808HisIle: 0.808 ± 0.236
0.404HisLys: 0.404 ± 0.444
1.616HisLeu: 1.616 ± 0.472
0.808HisMet: 0.808 ± 0.236
0.404HisAsn: 0.404 ± 0.208
1.616HisPro: 1.616 ± 0.181
1.212HisGln: 1.212 ± 0.028
1.616HisArg: 1.616 ± 0.181
1.212HisSer: 1.212 ± 0.028
0.0HisThr: 0.0 ± 0.0
0.808HisVal: 0.808 ± 0.236
0.0HisTrp: 0.0 ± 0.0
0.404HisTyr: 0.404 ± 0.208
0.0HisXaa: 0.0 ± 0.0
Ile
2.827IleAla: 2.827 ± 0.153
0.0IleCys: 0.0 ± 0.0
2.423IleAsp: 2.423 ± 2.012
2.019IleGlu: 2.019 ± 0.263
0.404IlePhe: 0.404 ± 0.444
2.423IleGly: 2.423 ± 0.055
1.212IleHis: 1.212 ± 0.625
1.616IleIle: 1.616 ± 0.181
1.212IleLys: 1.212 ± 0.68
3.635IleLeu: 3.635 ± 0.57
0.404IleMet: 0.404 ± 0.208
0.808IleAsn: 0.808 ± 0.417
1.212IlePro: 1.212 ± 0.028
0.808IleGln: 0.808 ± 0.236
4.847IleArg: 4.847 ± 2.719
2.019IleSer: 2.019 ± 0.916
2.423IleThr: 2.423 ± 0.055
1.616IleVal: 1.616 ± 0.833
0.404IleTrp: 0.404 ± 0.208
0.404IleTyr: 0.404 ± 0.444
0.0IleXaa: 0.0 ± 0.0
Lys
2.423LysAla: 2.423 ± 0.597
0.0LysCys: 0.0 ± 0.0
1.616LysAsp: 1.616 ± 0.472
2.019LysGlu: 2.019 ± 0.263
0.404LysPhe: 0.404 ± 0.444
4.039LysGly: 4.039 ± 0.126
0.808LysHis: 0.808 ± 0.236
2.827LysIle: 2.827 ± 0.499
2.423LysLys: 2.423 ± 0.055
3.231LysLeu: 3.231 ± 1.596
2.827LysMet: 2.827 ± 1.804
1.212LysAsn: 1.212 ± 0.68
1.212LysPro: 1.212 ± 1.332
0.808LysGln: 0.808 ± 0.236
3.635LysArg: 3.635 ± 0.735
3.231LysSer: 3.231 ± 0.361
2.423LysThr: 2.423 ± 0.707
5.654LysVal: 5.654 ± 0.998
1.616LysTrp: 1.616 ± 0.181
1.212LysTyr: 1.212 ± 0.68
0.0LysXaa: 0.0 ± 0.0
Leu
6.866LeuAla: 6.866 ± 0.279
1.616LeuCys: 1.616 ± 0.181
4.039LeuAsp: 4.039 ± 0.527
6.866LeuGlu: 6.866 ± 0.931
3.231LeuPhe: 3.231 ± 0.943
8.481LeuGly: 8.481 ± 0.845
2.019LeuHis: 2.019 ± 1.568
1.212LeuIle: 1.212 ± 0.68
3.231LeuLys: 3.231 ± 1.596
4.847LeuLeu: 4.847 ± 0.762
2.827LeuMet: 2.827 ± 1.804
3.635LeuAsn: 3.635 ± 0.57
0.808LeuPro: 0.808 ± 0.236
0.808LeuGln: 0.808 ± 0.888
7.27LeuArg: 7.27 ± 0.165
4.443LeuSer: 4.443 ± 0.318
7.674LeuThr: 7.674 ± 1.348
3.635LeuVal: 3.635 ± 0.083
1.616LeuTrp: 1.616 ± 0.472
1.616LeuTyr: 1.616 ± 0.181
0.0LeuXaa: 0.0 ± 0.0
Met
4.443MetAla: 4.443 ± 0.334
0.404MetCys: 0.404 ± 0.208
2.019MetAsp: 2.019 ± 0.263
2.827MetGlu: 2.827 ± 1.804
0.808MetPhe: 0.808 ± 0.417
2.423MetGly: 2.423 ± 0.055
0.808MetHis: 0.808 ± 0.888
0.808MetIle: 0.808 ± 0.236
0.404MetLys: 0.404 ± 0.208
1.212MetLeu: 1.212 ± 0.68
0.808MetMet: 0.808 ± 0.236
1.212MetAsn: 1.212 ± 0.68
2.019MetPro: 2.019 ± 0.263
0.404MetGln: 0.404 ± 0.444
3.635MetArg: 3.635 ± 1.387
2.827MetSer: 2.827 ± 1.151
0.808MetThr: 0.808 ± 0.236
1.616MetVal: 1.616 ± 0.833
1.212MetTrp: 1.212 ± 0.68
0.404MetTyr: 0.404 ± 0.208
0.0MetXaa: 0.0 ± 0.0
Asn
3.231AsnAla: 3.231 ± 1.014
0.808AsnCys: 0.808 ± 0.236
0.404AsnAsp: 0.404 ± 0.208
1.616AsnGlu: 1.616 ± 0.472
0.404AsnPhe: 0.404 ± 0.208
1.616AsnGly: 1.616 ± 0.472
0.0AsnHis: 0.0 ± 0.0
1.212AsnIle: 1.212 ± 0.028
0.808AsnLys: 0.808 ± 0.236
1.212AsnLeu: 1.212 ± 0.625
1.212AsnMet: 1.212 ± 0.68
0.0AsnAsn: 0.0 ± 0.0
2.827AsnPro: 2.827 ± 0.806
0.404AsnGln: 0.404 ± 0.208
0.404AsnArg: 0.404 ± 0.444
1.616AsnSer: 1.616 ± 0.833
2.827AsnThr: 2.827 ± 0.806
3.231AsnVal: 3.231 ± 0.361
1.212AsnTrp: 1.212 ± 0.028
1.212AsnTyr: 1.212 ± 0.68
0.0AsnXaa: 0.0 ± 0.0
Pro
3.231ProAla: 3.231 ± 1.014
0.808ProCys: 0.808 ± 0.236
2.827ProAsp: 2.827 ± 1.458
2.423ProGlu: 2.423 ± 0.707
1.212ProPhe: 1.212 ± 0.68
4.039ProGly: 4.039 ± 0.778
0.808ProHis: 0.808 ± 0.417
1.616ProIle: 1.616 ± 1.124
2.019ProLys: 2.019 ± 0.916
2.827ProLeu: 2.827 ± 1.151
1.212ProMet: 1.212 ± 0.028
0.808ProAsn: 0.808 ± 0.236
4.039ProPro: 4.039 ± 1.43
2.423ProGln: 2.423 ± 1.25
4.443ProArg: 4.443 ± 0.986
3.635ProSer: 3.635 ± 1.222
3.635ProThr: 3.635 ± 0.57
6.058ProVal: 6.058 ± 1.819
0.808ProTrp: 0.808 ± 0.236
2.019ProTyr: 2.019 ± 0.916
0.0ProXaa: 0.0 ± 0.0
Gln
1.212GlnAla: 1.212 ± 0.625
0.0GlnCys: 0.0 ± 0.0
1.616GlnAsp: 1.616 ± 0.181
0.808GlnGlu: 0.808 ± 0.417
0.404GlnPhe: 0.404 ± 0.208
4.039GlnGly: 4.039 ± 0.126
0.404GlnHis: 0.404 ± 0.208
0.808GlnIle: 0.808 ± 0.236
1.212GlnLys: 1.212 ± 0.028
2.019GlnLeu: 2.019 ± 0.263
0.808GlnMet: 0.808 ± 0.484
0.0GlnAsn: 0.0 ± 0.0
1.212GlnPro: 1.212 ± 0.028
0.808GlnGln: 0.808 ± 0.417
1.616GlnArg: 1.616 ± 0.833
0.808GlnSer: 0.808 ± 0.236
0.404GlnThr: 0.404 ± 0.208
1.212GlnVal: 1.212 ± 0.028
2.019GlnTrp: 2.019 ± 0.389
0.808GlnTyr: 0.808 ± 0.417
0.0GlnXaa: 0.0 ± 0.0
Arg
5.654ArgAla: 5.654 ± 1.611
1.616ArgCys: 1.616 ± 0.181
4.039ArgAsp: 4.039 ± 1.179
5.654ArgGlu: 5.654 ± 0.998
2.019ArgPhe: 2.019 ± 0.389
7.674ArgGly: 7.674 ± 1.262
1.616ArgHis: 1.616 ± 0.181
4.039ArgIle: 4.039 ± 0.126
3.231ArgLys: 3.231 ± 0.291
5.654ArgLeu: 5.654 ± 0.346
3.635ArgMet: 3.635 ± 0.083
1.212ArgAsn: 1.212 ± 0.028
2.019ArgPro: 2.019 ± 0.389
2.827ArgGln: 2.827 ± 0.806
6.462ArgArg: 6.462 ± 0.582
5.25ArgSer: 5.25 ± 0.098
6.058ArgThr: 6.058 ± 0.515
7.674ArgVal: 7.674 ± 1.348
3.635ArgTrp: 3.635 ± 2.04
2.423ArgTyr: 2.423 ± 0.055
0.0ArgXaa: 0.0 ± 0.0
Ser
4.847SerAla: 4.847 ± 1.195
0.808SerCys: 0.808 ± 0.417
6.058SerAsp: 6.058 ± 2.472
3.231SerGlu: 3.231 ± 0.361
1.212SerPhe: 1.212 ± 0.68
4.847SerGly: 4.847 ± 0.762
1.616SerHis: 1.616 ± 1.124
2.423SerIle: 2.423 ± 0.597
2.019SerLys: 2.019 ± 0.389
3.231SerLeu: 3.231 ± 0.361
1.212SerMet: 1.212 ± 0.625
1.616SerAsn: 1.616 ± 0.833
2.827SerPro: 2.827 ± 0.499
1.212SerGln: 1.212 ± 0.028
6.058SerArg: 6.058 ± 1.167
3.635SerSer: 3.635 ± 1.222
6.058SerThr: 6.058 ± 0.515
3.635SerVal: 3.635 ± 1.222
2.019SerTrp: 2.019 ± 0.263
1.212SerTyr: 1.212 ± 0.028
0.0SerXaa: 0.0 ± 0.0
Thr
4.443ThrAla: 4.443 ± 0.334
0.808ThrCys: 0.808 ± 0.236
4.847ThrAsp: 4.847 ± 1.195
2.827ThrGlu: 2.827 ± 0.153
1.616ThrPhe: 1.616 ± 0.181
6.462ThrGly: 6.462 ± 0.582
0.808ThrHis: 0.808 ± 0.417
1.616ThrIle: 1.616 ± 1.124
2.019ThrLys: 2.019 ± 0.916
5.654ThrLeu: 5.654 ± 1.611
2.423ThrMet: 2.423 ± 0.055
1.212ThrAsn: 1.212 ± 0.625
5.654ThrPro: 5.654 ± 0.306
0.808ThrGln: 0.808 ± 0.417
5.25ThrArg: 5.25 ± 0.098
2.827ThrSer: 2.827 ± 0.806
1.616ThrThr: 1.616 ± 0.833
2.827ThrVal: 2.827 ± 0.153
0.808ThrTrp: 0.808 ± 0.236
2.019ThrTyr: 2.019 ± 0.263
0.0ThrXaa: 0.0 ± 0.0
Val
6.462ValAla: 6.462 ± 2.028
1.616ValCys: 1.616 ± 0.181
5.654ValAsp: 5.654 ± 2.263
4.443ValGlu: 4.443 ± 0.334
1.212ValPhe: 1.212 ± 0.028
10.501ValGly: 10.501 ± 0.196
1.616ValHis: 1.616 ± 0.472
2.019ValIle: 2.019 ± 0.916
3.231ValLys: 3.231 ± 0.943
6.462ValLeu: 6.462 ± 0.071
2.019ValMet: 2.019 ± 0.389
3.635ValAsn: 3.635 ± 0.083
5.25ValPro: 5.25 ± 1.207
1.212ValGln: 1.212 ± 0.68
5.654ValArg: 5.654 ± 1.651
4.443ValSer: 4.443 ± 1.639
4.847ValThr: 4.847 ± 0.762
5.654ValVal: 5.654 ± 0.346
0.404ValTrp: 0.404 ± 0.444
0.404ValTyr: 0.404 ± 0.208
0.0ValXaa: 0.0 ± 0.0
Trp
5.25TrpAla: 5.25 ± 0.098
0.0TrpCys: 0.0 ± 0.0
1.616TrpAsp: 1.616 ± 0.472
1.212TrpGlu: 1.212 ± 0.028
1.212TrpPhe: 1.212 ± 0.028
2.423TrpGly: 2.423 ± 0.597
0.808TrpHis: 0.808 ± 0.236
1.616TrpIle: 1.616 ± 0.472
1.616TrpLys: 1.616 ± 1.124
2.827TrpLeu: 2.827 ± 0.153
0.808TrpMet: 0.808 ± 0.236
1.212TrpAsn: 1.212 ± 1.332
0.808TrpPro: 0.808 ± 0.236
0.404TrpGln: 0.404 ± 0.208
2.019TrpArg: 2.019 ± 0.916
1.616TrpSer: 1.616 ± 0.833
0.808TrpThr: 0.808 ± 0.888
1.212TrpVal: 1.212 ± 0.68
0.0TrpTrp: 0.0 ± 0.0
0.808TrpTyr: 0.808 ± 0.236
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.827TyrAla: 2.827 ± 0.806
0.0TyrCys: 0.0 ± 0.0
4.039TyrAsp: 4.039 ± 0.778
1.212TyrGlu: 1.212 ± 0.68
0.404TyrPhe: 0.404 ± 0.208
2.423TyrGly: 2.423 ± 0.055
0.404TyrHis: 0.404 ± 0.208
0.808TyrIle: 0.808 ± 0.236
1.616TyrLys: 1.616 ± 0.472
2.423TyrLeu: 2.423 ± 1.36
0.808TyrMet: 0.808 ± 0.417
0.808TyrAsn: 0.808 ± 0.417
1.212TyrPro: 1.212 ± 0.625
0.404TyrGln: 0.404 ± 0.208
0.404TyrArg: 0.404 ± 0.444
0.808TyrSer: 0.808 ± 0.236
1.212TyrThr: 1.212 ± 0.028
1.212TyrVal: 1.212 ± 0.68
2.423TyrTrp: 2.423 ± 1.36
0.404TyrTyr: 0.404 ± 0.208
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2477 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski