Amino acid dipepetide frequency for Avian orthoavulavirus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.422AlaAla: 7.422 ± 1.612
2.183AlaCys: 2.183 ± 1.006
2.183AlaAsp: 2.183 ± 0.541
4.584AlaGlu: 4.584 ± 1.045
1.965AlaPhe: 1.965 ± 0.472
3.056AlaGly: 3.056 ± 1.423
1.31AlaHis: 1.31 ± 0.456
3.711AlaIle: 3.711 ± 0.977
3.711AlaLys: 3.711 ± 0.32
7.204AlaLeu: 7.204 ± 2.256
1.965AlaMet: 1.965 ± 0.805
3.929AlaAsn: 3.929 ± 1.0
3.929AlaPro: 3.929 ± 1.195
3.493AlaGln: 3.493 ± 2.413
3.929AlaArg: 3.929 ± 0.727
5.239AlaSer: 5.239 ± 1.074
4.584AlaThr: 4.584 ± 1.672
7.204AlaVal: 7.204 ± 0.699
0.437AlaTrp: 0.437 ± 0.247
1.31AlaTyr: 1.31 ± 0.325
0.0AlaXaa: 0.0 ± 0.0
Cys
1.31CysAla: 1.31 ± 0.357
0.437CysCys: 0.437 ± 0.26
1.31CysAsp: 1.31 ± 0.609
0.218CysGlu: 0.218 ± 0.13
0.218CysPhe: 0.218 ± 0.21
0.218CysGly: 0.218 ± 0.295
0.0CysHis: 0.0 ± 0.0
1.091CysIle: 1.091 ± 0.693
0.873CysLys: 0.873 ± 0.295
2.401CysLeu: 2.401 ± 0.587
0.437CysMet: 0.437 ± 0.223
0.655CysAsn: 0.655 ± 0.248
0.873CysPro: 0.873 ± 0.439
0.655CysGln: 0.655 ± 0.271
1.31CysArg: 1.31 ± 0.277
1.965CysSer: 1.965 ± 0.589
1.31CysThr: 1.31 ± 0.397
0.655CysVal: 0.655 ± 0.278
0.0CysTrp: 0.0 ± 0.0
1.091CysTyr: 1.091 ± 0.28
0.0CysXaa: 0.0 ± 0.0
Asp
2.183AspAla: 2.183 ± 0.541
0.873AspCys: 0.873 ± 0.328
3.056AspAsp: 3.056 ± 0.76
2.401AspGlu: 2.401 ± 0.59
1.965AspPhe: 1.965 ± 0.672
2.838AspGly: 2.838 ± 0.489
0.873AspHis: 0.873 ± 0.344
3.056AspIle: 3.056 ± 0.816
2.401AspLys: 2.401 ± 1.219
4.802AspLeu: 4.802 ± 0.64
1.746AspMet: 1.746 ± 0.557
3.056AspAsn: 3.056 ± 0.866
3.711AspPro: 3.711 ± 0.771
1.746AspGln: 1.746 ± 0.369
1.746AspArg: 1.746 ± 0.626
4.584AspSer: 4.584 ± 0.916
5.021AspThr: 5.021 ± 0.847
2.62AspVal: 2.62 ± 0.683
0.655AspTrp: 0.655 ± 0.29
1.528AspTyr: 1.528 ± 0.64
0.0AspXaa: 0.0 ± 0.0
Glu
4.366GluAla: 4.366 ± 0.685
0.437GluCys: 0.437 ± 0.26
3.274GluAsp: 3.274 ± 1.269
3.711GluGlu: 3.711 ± 0.378
1.965GluPhe: 1.965 ± 0.736
3.493GluGly: 3.493 ± 0.866
0.437GluHis: 0.437 ± 0.205
2.838GluIle: 2.838 ± 0.712
3.274GluLys: 3.274 ± 0.636
5.894GluLeu: 5.894 ± 0.806
1.528GluMet: 1.528 ± 0.662
1.31GluAsn: 1.31 ± 0.609
0.655GluPro: 0.655 ± 0.39
1.091GluGln: 1.091 ± 0.315
2.183GluArg: 2.183 ± 0.467
3.274GluSer: 3.274 ± 0.578
3.056GluThr: 3.056 ± 1.096
2.838GluVal: 2.838 ± 1.119
0.218GluTrp: 0.218 ± 0.13
2.401GluTyr: 2.401 ± 0.926
0.0GluXaa: 0.0 ± 0.0
Phe
3.493PheAla: 3.493 ± 1.346
0.655PheCys: 0.655 ± 0.297
2.401PheAsp: 2.401 ± 0.496
1.528PheGlu: 1.528 ± 0.662
1.965PhePhe: 1.965 ± 0.574
1.528PheGly: 1.528 ± 0.935
0.655PheHis: 0.655 ± 0.39
1.528PheIle: 1.528 ± 0.507
1.31PheLys: 1.31 ± 0.454
2.62PheLeu: 2.62 ± 0.765
0.437PheMet: 0.437 ± 0.276
1.528PheAsn: 1.528 ± 0.263
1.528PhePro: 1.528 ± 0.523
0.655PheGln: 0.655 ± 0.248
1.528PheArg: 1.528 ± 0.639
2.401PheSer: 2.401 ± 0.753
2.838PheThr: 2.838 ± 0.958
2.401PheVal: 2.401 ± 0.445
0.437PheTrp: 0.437 ± 0.276
0.655PheTyr: 0.655 ± 0.394
0.0PheXaa: 0.0 ± 0.0
Gly
3.493GlyAla: 3.493 ± 1.001
1.091GlyCys: 1.091 ± 0.657
5.239GlyAsp: 5.239 ± 1.065
1.965GlyGlu: 1.965 ± 0.715
1.31GlyPhe: 1.31 ± 0.277
5.021GlyGly: 5.021 ± 1.44
0.655GlyHis: 0.655 ± 0.295
3.493GlyIle: 3.493 ± 1.193
2.838GlyLys: 2.838 ± 0.825
5.239GlyLeu: 5.239 ± 1.211
1.31GlyMet: 1.31 ± 0.622
4.366GlyAsn: 4.366 ± 1.875
2.183GlyPro: 2.183 ± 0.897
1.528GlyGln: 1.528 ± 0.318
3.274GlyArg: 3.274 ± 0.795
5.676GlySer: 5.676 ± 1.913
3.711GlyThr: 3.711 ± 1.436
4.802GlyVal: 4.802 ± 1.063
0.218GlyTrp: 0.218 ± 0.21
1.965GlyTyr: 1.965 ± 0.773
0.0GlyXaa: 0.0 ± 0.0
His
1.528HisAla: 1.528 ± 0.662
0.437HisCys: 0.437 ± 0.26
1.091HisAsp: 1.091 ± 0.329
1.091HisGlu: 1.091 ± 0.28
0.655HisPhe: 0.655 ± 0.271
1.31HisGly: 1.31 ± 0.543
0.0HisHis: 0.0 ± 0.0
1.091HisIle: 1.091 ± 0.505
0.437HisLys: 0.437 ± 0.26
2.401HisLeu: 2.401 ± 1.242
0.218HisMet: 0.218 ± 0.13
0.873HisAsn: 0.873 ± 0.373
2.401HisPro: 2.401 ± 0.914
1.091HisGln: 1.091 ± 0.431
0.218HisArg: 0.218 ± 0.13
2.401HisSer: 2.401 ± 0.622
1.091HisThr: 1.091 ± 0.352
1.528HisVal: 1.528 ± 0.369
0.0HisTrp: 0.0 ± 0.0
0.218HisTyr: 0.218 ± 0.21
0.0HisXaa: 0.0 ± 0.0
Ile
5.021IleAla: 5.021 ± 0.936
0.218IleCys: 0.218 ± 0.268
2.62IleAsp: 2.62 ± 0.615
3.929IleGlu: 3.929 ± 1.369
1.746IlePhe: 1.746 ± 0.405
3.711IleGly: 3.711 ± 0.699
1.746IleHis: 1.746 ± 0.859
3.493IleIle: 3.493 ± 1.093
3.056IleLys: 3.056 ± 0.731
6.985IleLeu: 6.985 ± 1.189
1.965IleMet: 1.965 ± 0.732
1.965IleAsn: 1.965 ± 0.801
2.401IlePro: 2.401 ± 0.887
3.929IleGln: 3.929 ± 1.272
2.838IleArg: 2.838 ± 0.276
5.239IleSer: 5.239 ± 0.927
5.239IleThr: 5.239 ± 1.039
2.838IleVal: 2.838 ± 0.905
0.218IleTrp: 0.218 ± 0.13
1.965IleTyr: 1.965 ± 0.564
0.0IleXaa: 0.0 ± 0.0
Lys
3.274LysAla: 3.274 ± 0.473
0.218LysCys: 0.218 ± 0.13
2.838LysAsp: 2.838 ± 0.632
2.62LysGlu: 2.62 ± 0.744
1.31LysPhe: 1.31 ± 0.78
2.401LysGly: 2.401 ± 0.825
1.31LysHis: 1.31 ± 0.416
3.929LysIle: 3.929 ± 1.073
3.711LysLys: 3.711 ± 1.381
5.894LysLeu: 5.894 ± 1.304
1.528LysMet: 1.528 ± 0.683
2.183LysAsn: 2.183 ± 0.698
1.528LysPro: 1.528 ± 0.722
2.62LysGln: 2.62 ± 0.899
2.183LysArg: 2.183 ± 0.358
2.838LysSer: 2.838 ± 0.756
2.838LysThr: 2.838 ± 1.081
3.493LysVal: 3.493 ± 0.724
0.218LysTrp: 0.218 ± 0.13
2.401LysTyr: 2.401 ± 1.112
0.0LysXaa: 0.0 ± 0.0
Leu
7.64LeuAla: 7.64 ± 1.171
1.965LeuCys: 1.965 ± 0.574
5.457LeuAsp: 5.457 ± 1.773
5.239LeuGlu: 5.239 ± 1.158
4.148LeuPhe: 4.148 ± 1.48
6.33LeuGly: 6.33 ± 1.182
2.401LeuHis: 2.401 ± 1.059
6.33LeuIle: 6.33 ± 1.223
4.802LeuLys: 4.802 ± 0.729
10.041LeuLeu: 10.041 ± 1.498
3.056LeuMet: 3.056 ± 0.416
4.366LeuAsn: 4.366 ± 0.599
2.838LeuPro: 2.838 ± 0.82
2.401LeuGln: 2.401 ± 0.909
5.457LeuArg: 5.457 ± 0.602
12.006LeuSer: 12.006 ± 1.038
8.732LeuThr: 8.732 ± 1.649
6.112LeuVal: 6.112 ± 0.669
1.31LeuTrp: 1.31 ± 0.48
5.239LeuTyr: 5.239 ± 0.65
0.0LeuXaa: 0.0 ± 0.0
Met
1.746MetAla: 1.746 ± 0.645
0.437MetCys: 0.437 ± 0.26
0.873MetAsp: 0.873 ± 0.32
1.965MetGlu: 1.965 ± 0.759
0.655MetPhe: 0.655 ± 0.39
1.746MetGly: 1.746 ± 0.334
0.655MetHis: 0.655 ± 0.262
1.528MetIle: 1.528 ± 0.557
0.873MetLys: 0.873 ± 0.628
2.62MetLeu: 2.62 ± 0.532
1.528MetMet: 1.528 ± 1.272
0.873MetAsn: 0.873 ± 0.373
0.437MetPro: 0.437 ± 0.276
0.437MetGln: 0.437 ± 0.393
1.965MetArg: 1.965 ± 1.194
3.274MetSer: 3.274 ± 0.624
1.965MetThr: 1.965 ± 0.529
1.528MetVal: 1.528 ± 0.567
0.0MetTrp: 0.0 ± 0.0
0.873MetTyr: 0.873 ± 0.446
0.0MetXaa: 0.0 ± 0.0
Asn
2.183AsnAla: 2.183 ± 0.688
0.655AsnCys: 0.655 ± 0.248
2.401AsnAsp: 2.401 ± 0.568
1.965AsnGlu: 1.965 ± 0.517
0.873AsnPhe: 0.873 ± 0.275
2.401AsnGly: 2.401 ± 0.737
1.746AsnHis: 1.746 ± 0.391
4.148AsnIle: 4.148 ± 1.275
3.711AsnLys: 3.711 ± 0.446
5.894AsnLeu: 5.894 ± 1.195
0.873AsnMet: 0.873 ± 0.446
1.746AsnAsn: 1.746 ± 0.929
2.838AsnPro: 2.838 ± 0.617
2.401AsnGln: 2.401 ± 0.601
1.965AsnArg: 1.965 ± 0.457
3.711AsnSer: 3.711 ± 0.62
3.929AsnThr: 3.929 ± 0.704
2.183AsnVal: 2.183 ± 0.709
0.873AsnTrp: 0.873 ± 0.52
0.873AsnTyr: 0.873 ± 0.265
0.0AsnXaa: 0.0 ± 0.0
Pro
4.148ProAla: 4.148 ± 1.089
0.873ProCys: 0.873 ± 0.41
2.183ProAsp: 2.183 ± 0.657
2.838ProGlu: 2.838 ± 0.869
1.746ProPhe: 1.746 ± 0.623
3.056ProGly: 3.056 ± 0.893
1.31ProHis: 1.31 ± 0.741
0.873ProIle: 0.873 ± 0.558
1.965ProLys: 1.965 ± 0.622
4.802ProLeu: 4.802 ± 1.004
1.528ProMet: 1.528 ± 0.713
3.056ProAsn: 3.056 ± 0.51
2.838ProPro: 2.838 ± 0.975
2.401ProGln: 2.401 ± 1.187
1.528ProArg: 1.528 ± 0.551
4.148ProSer: 4.148 ± 1.335
2.838ProThr: 2.838 ± 0.653
2.401ProVal: 2.401 ± 0.758
0.218ProTrp: 0.218 ± 0.295
2.401ProTyr: 2.401 ± 0.323
0.0ProXaa: 0.0 ± 0.0
Gln
3.274GlnAla: 3.274 ± 1.073
0.218GlnCys: 0.218 ± 0.13
2.183GlnAsp: 2.183 ± 0.917
2.838GlnGlu: 2.838 ± 0.619
1.528GlnPhe: 1.528 ± 0.87
3.274GlnGly: 3.274 ± 2.191
0.218GlnHis: 0.218 ± 0.13
3.274GlnIle: 3.274 ± 0.93
1.965GlnLys: 1.965 ± 0.665
4.802GlnLeu: 4.802 ± 1.032
0.873GlnMet: 0.873 ± 0.259
1.528GlnAsn: 1.528 ± 0.506
1.965GlnPro: 1.965 ± 1.663
2.401GlnGln: 2.401 ± 1.204
3.056GlnArg: 3.056 ± 0.593
1.746GlnSer: 1.746 ± 0.52
1.965GlnThr: 1.965 ± 0.631
4.366GlnVal: 4.366 ± 0.854
0.437GlnTrp: 0.437 ± 0.247
0.873GlnTyr: 0.873 ± 0.397
0.0GlnXaa: 0.0 ± 0.0
Arg
3.493ArgAla: 3.493 ± 0.784
1.31ArgCys: 1.31 ± 0.397
1.31ArgAsp: 1.31 ± 0.406
2.838ArgGlu: 2.838 ± 0.89
0.437ArgPhe: 0.437 ± 0.353
2.62ArgGly: 2.62 ± 0.314
0.873ArgHis: 0.873 ± 0.52
4.584ArgIle: 4.584 ± 1.49
2.183ArgLys: 2.183 ± 0.432
6.112ArgLeu: 6.112 ± 1.184
1.31ArgMet: 1.31 ± 0.386
2.401ArgAsn: 2.401 ± 0.871
2.401ArgPro: 2.401 ± 0.773
1.965ArgGln: 1.965 ± 0.579
2.183ArgArg: 2.183 ± 0.67
5.457ArgSer: 5.457 ± 1.129
2.401ArgThr: 2.401 ± 0.485
4.802ArgVal: 4.802 ± 0.989
0.218ArgTrp: 0.218 ± 0.313
1.091ArgTyr: 1.091 ± 0.488
0.0ArgXaa: 0.0 ± 0.0
Ser
6.33SerAla: 6.33 ± 1.827
1.965SerCys: 1.965 ± 0.641
3.929SerAsp: 3.929 ± 0.613
3.274SerGlu: 3.274 ± 1.611
2.62SerPhe: 2.62 ± 1.061
6.112SerGly: 6.112 ± 0.65
2.62SerHis: 2.62 ± 0.696
5.457SerIle: 5.457 ± 1.264
3.056SerLys: 3.056 ± 0.63
8.077SerLeu: 8.077 ± 0.658
1.746SerMet: 1.746 ± 0.386
6.112SerAsn: 6.112 ± 0.928
5.457SerPro: 5.457 ± 1.032
5.239SerGln: 5.239 ± 2.273
4.148SerArg: 4.148 ± 0.923
8.95SerSer: 8.95 ± 1.377
5.676SerThr: 5.676 ± 1.172
6.767SerVal: 6.767 ± 1.313
0.873SerTrp: 0.873 ± 0.52
2.62SerTyr: 2.62 ± 0.701
0.0SerXaa: 0.0 ± 0.0
Thr
5.021ThrAla: 5.021 ± 1.299
1.746ThrCys: 1.746 ± 0.415
3.929ThrAsp: 3.929 ± 0.476
2.62ThrGlu: 2.62 ± 0.744
2.183ThrPhe: 2.183 ± 0.432
3.493ThrGly: 3.493 ± 1.236
1.31ThrHis: 1.31 ± 0.543
4.584ThrIle: 4.584 ± 0.84
2.62ThrLys: 2.62 ± 0.649
7.422ThrLeu: 7.422 ± 1.862
0.873ThrMet: 0.873 ± 0.275
2.183ThrAsn: 2.183 ± 0.68
3.711ThrPro: 3.711 ± 1.408
3.929ThrGln: 3.929 ± 0.78
5.457ThrArg: 5.457 ± 1.381
7.422ThrSer: 7.422 ± 1.923
5.021ThrThr: 5.021 ± 1.517
5.021ThrVal: 5.021 ± 0.998
0.437ThrTrp: 0.437 ± 0.205
1.965ThrTyr: 1.965 ± 0.612
0.0ThrXaa: 0.0 ± 0.0
Val
5.239ValAla: 5.239 ± 0.859
0.218ValCys: 0.218 ± 0.313
2.62ValAsp: 2.62 ± 0.96
1.528ValGlu: 1.528 ± 0.355
3.274ValPhe: 3.274 ± 0.726
4.366ValGly: 4.366 ± 1.088
1.528ValHis: 1.528 ± 0.502
3.493ValIle: 3.493 ± 0.859
3.929ValLys: 3.929 ± 1.073
7.422ValLeu: 7.422 ± 0.909
1.31ValMet: 1.31 ± 0.373
3.274ValAsn: 3.274 ± 1.101
3.711ValPro: 3.711 ± 0.521
2.62ValGln: 2.62 ± 0.463
2.62ValArg: 2.62 ± 0.835
6.767ValSer: 6.767 ± 0.584
6.549ValThr: 6.549 ± 1.647
4.148ValVal: 4.148 ± 0.74
0.655ValTrp: 0.655 ± 0.29
1.528ValTyr: 1.528 ± 0.495
0.0ValXaa: 0.0 ± 0.0
Trp
0.437TrpAla: 0.437 ± 0.26
0.0TrpCys: 0.0 ± 0.0
0.0TrpAsp: 0.0 ± 0.0
0.437TrpGlu: 0.437 ± 0.59
0.655TrpPhe: 0.655 ± 0.271
0.655TrpGly: 0.655 ± 0.29
0.0TrpHis: 0.0 ± 0.0
0.655TrpIle: 0.655 ± 0.39
0.437TrpLys: 0.437 ± 0.26
0.655TrpLeu: 0.655 ± 0.248
0.0TrpMet: 0.0 ± 0.0
0.0TrpAsn: 0.0 ± 0.0
0.218TrpPro: 0.218 ± 0.13
0.0TrpGln: 0.0 ± 0.0
0.873TrpArg: 0.873 ± 0.278
1.31TrpSer: 1.31 ± 0.341
0.655TrpThr: 0.655 ± 0.295
0.437TrpVal: 0.437 ± 0.353
0.0TrpTrp: 0.0 ± 0.0
0.218TrpTyr: 0.218 ± 0.13
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.746TyrAla: 1.746 ± 0.643
1.091TyrCys: 1.091 ± 0.612
1.965TyrAsp: 1.965 ± 0.918
0.655TyrGlu: 0.655 ± 0.575
0.873TyrPhe: 0.873 ± 0.275
1.746TyrGly: 1.746 ± 0.228
0.437TyrHis: 0.437 ± 0.376
1.965TyrIle: 1.965 ± 0.44
2.183TyrLys: 2.183 ± 0.59
4.584TyrLeu: 4.584 ± 1.655
1.528TyrMet: 1.528 ± 0.714
1.965TyrAsn: 1.965 ± 0.621
1.528TyrPro: 1.528 ± 0.784
2.183TyrGln: 2.183 ± 0.728
1.528TyrArg: 1.528 ± 0.377
2.62TyrSer: 2.62 ± 0.453
1.528TyrThr: 1.528 ± 0.79
0.655TyrVal: 0.655 ± 0.311
0.218TyrTrp: 0.218 ± 0.13
1.965TyrTyr: 1.965 ± 0.773
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 6 proteins (4582 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski