Amino acid dipepetide frequency for Palleronia abyssalis

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	16.473AlaAla: 16.473 ± 0.138	1.098AlaCys: 1.098 ± 0.031	7.14AlaAsp: 7.14 ± 0.084	8.183AlaGlu: 8.183 ± 0.099	4.504AlaPhe: 4.504 ± 0.06	10.43AlaGly: 10.43 ± 0.098	2.294AlaHis: 2.294 ± 0.046	6.138AlaIle: 6.138 ± 0.072	3.302AlaLys: 3.302 ± 0.063	13.314AlaLeu: 13.314 ± 0.132	3.833AlaMet: 3.833 ± 0.058	2.57AlaAsn: 2.57 ± 0.045	5.889AlaPro: 5.889 ± 0.08	4.309AlaGln: 4.309 ± 0.062	9.287AlaArg: 9.287 ± 0.101	5.597AlaSer: 5.597 ± 0.064	6.165AlaThr: 6.165 ± 0.079	8.497AlaVal: 8.497 ± 0.094	1.625AlaTrp: 1.625 ± 0.037	2.406AlaTyr: 2.406 ± 0.046	0.0AlaXaa: 0.0 ± 0.0
Cys	1.054CysAla: 1.054 ± 0.031	0.136CysCys: 0.136 ± 0.011	0.624CysAsp: 0.624 ± 0.024	0.434CysGlu: 0.434 ± 0.017	0.314CysPhe: 0.314 ± 0.015	0.9CysGly: 0.9 ± 0.03	0.254CysHis: 0.254 ± 0.013	0.411CysIle: 0.411 ± 0.017	0.169CysLys: 0.169 ± 0.012	0.903CysLeu: 0.903 ± 0.023	0.151CysMet: 0.151 ± 0.01	0.196CysAsn: 0.196 ± 0.011	0.5CysPro: 0.5 ± 0.019	0.223CysGln: 0.223 ± 0.014	0.656CysArg: 0.656 ± 0.018	0.412CysSer: 0.412 ± 0.02	0.416CysThr: 0.416 ± 0.018	0.661CysVal: 0.661 ± 0.023	0.115CysTrp: 0.115 ± 0.008	0.197CysTyr: 0.197 ± 0.012	0.0CysXaa: 0.0 ± 0.0
Asp	7.945AspAla: 7.945 ± 0.097	0.516AspCys: 0.516 ± 0.021	3.911AspAsp: 3.911 ± 0.072	3.829AspGlu: 3.829 ± 0.061	2.165AspPhe: 2.165 ± 0.048	5.984AspGly: 5.984 ± 0.076	1.431AspHis: 1.431 ± 0.041	3.097AspIle: 3.097 ± 0.051	1.409AspLys: 1.409 ± 0.033	6.897AspLeu: 6.897 ± 0.09	1.697AspMet: 1.697 ± 0.037	1.132AspAsn: 1.132 ± 0.029	4.119AspPro: 4.119 ± 0.068	1.9AspGln: 1.9 ± 0.035	5.661AspArg: 5.661 ± 0.072	2.141AspSer: 2.141 ± 0.035	3.263AspThr: 3.263 ± 0.054	4.395AspVal: 4.395 ± 0.056	1.321AspTrp: 1.321 ± 0.033	1.462AspTyr: 1.462 ± 0.038	0.0AspXaa: 0.0 ± 0.0
Glu	8.14GluAla: 8.14 ± 0.092	0.386GluCys: 0.386 ± 0.022	3.838GluAsp: 3.838 ± 0.062	3.525GluGlu: 3.525 ± 0.058	1.692GluPhe: 1.692 ± 0.039	5.266GluGly: 5.266 ± 0.063	1.072GluHis: 1.072 ± 0.03	3.691GluIle: 3.691 ± 0.059	1.842GluLys: 1.842 ± 0.041	5.017GluLeu: 5.017 ± 0.075	1.801GluMet: 1.801 ± 0.042	1.583GluAsn: 1.583 ± 0.043	2.499GluPro: 2.499 ± 0.053	1.87GluGln: 1.87 ± 0.044	4.577GluArg: 4.577 ± 0.064	2.344GluSer: 2.344 ± 0.042	4.053GluThr: 4.053 ± 0.052	4.424GluVal: 4.424 ± 0.056	0.7GluTrp: 0.7 ± 0.023	1.045GluTyr: 1.045 ± 0.028	0.0GluXaa: 0.0 ± 0.0
Phe	4.491PheAla: 4.491 ± 0.062	0.406PheCys: 0.406 ± 0.018	2.917PheAsp: 2.917 ± 0.056	2.163PheGlu: 2.163 ± 0.044	1.38PhePhe: 1.38 ± 0.039	3.611PheGly: 3.611 ± 0.06	0.745PheHis: 0.745 ± 0.023	1.509PheIle: 1.509 ± 0.04	0.749PheLys: 0.749 ± 0.025	3.465PheLeu: 3.465 ± 0.062	0.806PheMet: 0.806 ± 0.021	0.886PheAsn: 0.886 ± 0.026	1.631PhePro: 1.631 ± 0.038	0.962PheGln: 0.962 ± 0.026	2.292PheArg: 2.292 ± 0.046	1.961PheSer: 1.961 ± 0.04	2.046PheThr: 2.046 ± 0.043	2.718PheVal: 2.718 ± 0.046	0.554PheTrp: 0.554 ± 0.024	0.889PheTyr: 0.889 ± 0.025	0.0PheXaa: 0.0 ± 0.0
Gly	9.922GlyAla: 9.922 ± 0.09	0.867GlyCys: 0.867 ± 0.026	5.075GlyAsp: 5.075 ± 0.076	4.717GlyGlu: 4.717 ± 0.064	3.491GlyPhe: 3.491 ± 0.051	7.564GlyGly: 7.564 ± 0.093	1.909GlyHis: 1.909 ± 0.038	4.669GlyIle: 4.669 ± 0.063	2.647GlyLys: 2.647 ± 0.05	9.229GlyLeu: 9.229 ± 0.098	2.628GlyMet: 2.628 ± 0.056	1.964GlyAsn: 1.964 ± 0.05	4.087GlyPro: 4.087 ± 0.052	3.129GlyGln: 3.129 ± 0.053	6.551GlyArg: 6.551 ± 0.069	4.312GlySer: 4.312 ± 0.065	5.136GlyThr: 5.136 ± 0.074	6.442GlyVal: 6.442 ± 0.077	1.515GlyTrp: 1.515 ± 0.041	2.23GlyTyr: 2.23 ± 0.041	0.0GlyXaa: 0.0 ± 0.0
His	2.44HisAla: 2.44 ± 0.051	0.225HisCys: 0.225 ± 0.012	1.335HisAsp: 1.335 ± 0.035	1.115HisGlu: 1.115 ± 0.03	0.732HisPhe: 0.732 ± 0.022	1.901HisGly: 1.901 ± 0.036	0.564HisHis: 0.564 ± 0.025	0.934HisIle: 0.934 ± 0.028	0.451HisLys: 0.451 ± 0.02	2.065HisLeu: 2.065 ± 0.038	0.514HisMet: 0.514 ± 0.022	0.38HisAsn: 0.38 ± 0.017	1.352HisPro: 1.352 ± 0.035	0.538HisGln: 0.538 ± 0.019	1.465HisArg: 1.465 ± 0.044	0.882HisSer: 0.882 ± 0.026	0.824HisThr: 0.824 ± 0.026	1.58HisVal: 1.58 ± 0.031	0.344HisTrp: 0.344 ± 0.017	0.501HisTyr: 0.501 ± 0.021	0.0HisXaa: 0.0 ± 0.0
Ile	7.181IleAla: 7.181 ± 0.083	0.572IleCys: 0.572 ± 0.018	3.736IleAsp: 3.736 ± 0.06	3.537IleGlu: 3.537 ± 0.053	1.743IlePhe: 1.743 ± 0.039	4.888IleGly: 4.888 ± 0.071	0.942IleHis: 0.942 ± 0.029	1.857IleIle: 1.857 ± 0.05	1.03IleLys: 1.03 ± 0.033	5.042IleLeu: 5.042 ± 0.082	1.058IleMet: 1.058 ± 0.031	1.099IleAsn: 1.099 ± 0.032	2.437IlePro: 2.437 ± 0.048	1.175IleGln: 1.175 ± 0.032	3.436IleArg: 3.436 ± 0.052	2.801IleSer: 2.801 ± 0.045	2.589IleThr: 2.589 ± 0.046	4.224IleVal: 4.224 ± 0.068	0.715IleTrp: 0.715 ± 0.022	1.115IleTyr: 1.115 ± 0.032	0.0IleXaa: 0.0 ± 0.0
Lys	3.29LysAla: 3.29 ± 0.06	0.143LysCys: 0.143 ± 0.01	1.624LysAsp: 1.624 ± 0.039	1.357LysGlu: 1.357 ± 0.037	0.744LysPhe: 0.744 ± 0.023	2.365LysGly: 2.365 ± 0.048	0.503LysHis: 0.503 ± 0.019	1.434LysIle: 1.434 ± 0.037	1.022LysLys: 1.022 ± 0.037	2.552LysLeu: 2.552 ± 0.055	0.755LysMet: 0.755 ± 0.028	0.667LysAsn: 0.667 ± 0.02	1.45LysPro: 1.45 ± 0.035	0.7LysGln: 0.7 ± 0.022	2.149LysArg: 2.149 ± 0.051	1.565LysSer: 1.565 ± 0.039	1.791LysThr: 1.791 ± 0.039	2.04LysVal: 2.04 ± 0.05	0.328LysTrp: 0.328 ± 0.017	0.48LysTyr: 0.48 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	12.653LeuAla: 12.653 ± 0.11	0.932LeuCys: 0.932 ± 0.027	6.417LeuAsp: 6.417 ± 0.076	5.085LeuGlu: 5.085 ± 0.071	3.51LeuPhe: 3.51 ± 0.062	8.746LeuGly: 8.746 ± 0.09	1.896LeuHis: 1.896 ± 0.04	5.285LeuIle: 5.285 ± 0.082	2.873LeuLys: 2.873 ± 0.056	8.822LeuLeu: 8.822 ± 0.105	2.458LeuMet: 2.458 ± 0.043	2.446LeuAsn: 2.446 ± 0.046	5.661LeuPro: 5.661 ± 0.086	2.582LeuGln: 2.582 ± 0.045	7.139LeuArg: 7.139 ± 0.084	6.927LeuSer: 6.927 ± 0.085	6.074LeuThr: 6.074 ± 0.073	6.908LeuVal: 6.908 ± 0.085	1.286LeuTrp: 1.286 ± 0.034	1.951LeuTyr: 1.951 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	3.342MetAla: 3.342 ± 0.05	0.171MetCys: 0.171 ± 0.011	1.433MetAsp: 1.433 ± 0.04	1.321MetGlu: 1.321 ± 0.034	0.775MetPhe: 0.775 ± 0.024	2.359MetGly: 2.359 ± 0.043	0.475MetHis: 0.475 ± 0.019	1.536MetIle: 1.536 ± 0.034	0.976MetLys: 0.976 ± 0.031	2.541MetLeu: 2.541 ± 0.043	0.726MetMet: 0.726 ± 0.028	0.802MetAsn: 0.802 ± 0.025	1.568MetPro: 1.568 ± 0.032	0.938MetGln: 0.938 ± 0.03	1.935MetArg: 1.935 ± 0.042	1.741MetSer: 1.741 ± 0.036	2.133MetThr: 2.133 ± 0.035	1.773MetVal: 1.773 ± 0.034	0.254MetTrp: 0.254 ± 0.013	0.314MetTyr: 0.314 ± 0.014	0.0MetXaa: 0.0 ± 0.0
Asn	2.965AsnAla: 2.965 ± 0.053	0.224AsnCys: 0.224 ± 0.013	1.39AsnAsp: 1.39 ± 0.036	1.189AsnGlu: 1.189 ± 0.032	0.878AsnPhe: 0.878 ± 0.024	2.141AsnGly: 2.141 ± 0.046	0.461AsnHis: 0.461 ± 0.016	1.19AsnIle: 1.19 ± 0.032	0.494AsnLys: 0.494 ± 0.019	2.436AsnLeu: 2.436 ± 0.038	0.594AsnMet: 0.594 ± 0.023	0.525AsnAsn: 0.525 ± 0.023	1.712AsnPro: 1.712 ± 0.035	0.646AsnGln: 0.646 ± 0.022	1.735AsnArg: 1.735 ± 0.037	1.02AsnSer: 1.02 ± 0.03	1.124AsnThr: 1.124 ± 0.027	1.737AsnVal: 1.737 ± 0.038	0.387AsnTrp: 0.387 ± 0.016	0.58AsnTyr: 0.58 ± 0.02	0.0AsnXaa: 0.0 ± 0.0
Pro	5.731ProAla: 5.731 ± 0.082	0.399ProCys: 0.399 ± 0.02	4.503ProAsp: 4.503 ± 0.064	4.331ProGlu: 4.331 ± 0.063	1.972ProPhe: 1.972 ± 0.039	4.808ProGly: 4.808 ± 0.063	1.104ProHis: 1.104 ± 0.028	2.295ProIle: 2.295 ± 0.047	1.506ProLys: 1.506 ± 0.035	4.564ProLeu: 4.564 ± 0.065	1.333ProMet: 1.333 ± 0.03	1.306ProAsn: 1.306 ± 0.031	2.588ProPro: 2.588 ± 0.06	1.617ProGln: 1.617 ± 0.038	3.116ProArg: 3.116 ± 0.049	2.72ProSer: 2.72 ± 0.051	2.537ProThr: 2.537 ± 0.045	4.226ProVal: 4.226 ± 0.062	0.742ProTrp: 0.742 ± 0.025	1.11ProTyr: 1.11 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.791GlnAla: 3.791 ± 0.06	0.179GlnCys: 0.179 ± 0.011	1.793GlnAsp: 1.793 ± 0.035	1.544GlnGlu: 1.544 ± 0.037	1.01GlnPhe: 1.01 ± 0.031	2.592GlnGly: 2.592 ± 0.044	0.546GlnHis: 0.546 ± 0.022	1.958GlnIle: 1.958 ± 0.04	0.977GlnLys: 0.977 ± 0.029	2.603GlnLeu: 2.603 ± 0.045	1.015GlnMet: 1.015 ± 0.027	0.885GlnAsn: 0.885 ± 0.028	1.557GlnPro: 1.557 ± 0.034	1.068GlnGln: 1.068 ± 0.035	2.168GlnArg: 2.168 ± 0.041	1.858GlnSer: 1.858 ± 0.038	1.913GlnThr: 1.913 ± 0.042	2.21GlnVal: 2.21 ± 0.044	0.338GlnTrp: 0.338 ± 0.017	0.546GlnTyr: 0.546 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	8.587ArgAla: 8.587 ± 0.097	0.519ArgCys: 0.519 ± 0.02	4.933ArgAsp: 4.933 ± 0.074	4.079ArgGlu: 4.079 ± 0.063	2.744ArgPhe: 2.744 ± 0.045	4.978ArgGly: 4.978 ± 0.064	1.699ArgHis: 1.699 ± 0.039	4.292ArgIle: 4.292 ± 0.057	2.142ArgLys: 2.142 ± 0.046	7.796ArgLeu: 7.796 ± 0.082	2.18ArgMet: 2.18 ± 0.045	1.759ArgAsn: 1.759 ± 0.038	3.824ArgPro: 3.824 ± 0.056	2.474ArgGln: 2.474 ± 0.05	5.763ArgArg: 5.763 ± 0.073	3.593ArgSer: 3.593 ± 0.061	3.715ArgThr: 3.715 ± 0.062	5.155ArgVal: 5.155 ± 0.065	0.972ArgTrp: 0.972 ± 0.028	1.553ArgTyr: 1.553 ± 0.043	0.0ArgXaa: 0.0 ± 0.0
Ser	5.695SerAla: 5.695 ± 0.059	0.422SerCys: 0.422 ± 0.018	3.535SerAsp: 3.535 ± 0.056	3.089SerGlu: 3.089 ± 0.05	2.149SerPhe: 2.149 ± 0.04	5.314SerGly: 5.314 ± 0.067	1.046SerHis: 1.046 ± 0.026	2.516SerIle: 2.516 ± 0.049	1.339SerLys: 1.339 ± 0.035	4.949SerLeu: 4.949 ± 0.071	1.346SerMet: 1.346 ± 0.032	1.294SerAsn: 1.294 ± 0.033	2.553SerPro: 2.553 ± 0.045	1.643SerGln: 1.643 ± 0.035	3.546SerArg: 3.546 ± 0.061	2.553SerSer: 2.553 ± 0.05	2.656SerThr: 2.656 ± 0.049	3.861SerVal: 3.861 ± 0.059	0.67SerTrp: 0.67 ± 0.025	1.25SerTyr: 1.25 ± 0.033	0.0SerXaa: 0.0 ± 0.0
Thr	6.406ThrAla: 6.406 ± 0.08	0.491ThrCys: 0.491 ± 0.02	3.394ThrAsp: 3.394 ± 0.059	3.193ThrGlu: 3.193 ± 0.054	2.108ThrPhe: 2.108 ± 0.039	5.547ThrGly: 5.547 ± 0.074	1.107ThrHis: 1.107 ± 0.029	2.702ThrIle: 2.702 ± 0.051	1.302ThrLys: 1.302 ± 0.032	6.152ThrLeu: 6.152 ± 0.078	1.36ThrMet: 1.36 ± 0.03	1.207ThrAsn: 1.207 ± 0.034	3.451ThrPro: 3.451 ± 0.053	1.528ThrGln: 1.528 ± 0.032	3.828ThrArg: 3.828 ± 0.056	2.78ThrSer: 2.78 ± 0.049	2.847ThrThr: 2.847 ± 0.049	4.479ThrVal: 4.479 ± 0.053	0.733ThrTrp: 0.733 ± 0.022	1.252ThrTyr: 1.252 ± 0.03	0.0ThrXaa: 0.0 ± 0.0
Val	9.127ValAla: 9.127 ± 0.086	0.653ValCys: 0.653 ± 0.018	4.306ValAsp: 4.306 ± 0.064	4.812ValGlu: 4.812 ± 0.063	2.884ValPhe: 2.884 ± 0.052	5.629ValGly: 5.629 ± 0.074	1.301ValHis: 1.301 ± 0.032	3.996ValIle: 3.996 ± 0.062	1.842ValLys: 1.842 ± 0.046	7.537ValLeu: 7.537 ± 0.08	2.031ValMet: 2.031 ± 0.045	1.832ValAsn: 1.832 ± 0.039	3.808ValPro: 3.808 ± 0.052	2.006ValGln: 2.006 ± 0.043	4.644ValArg: 4.644 ± 0.065	4.243ValSer: 4.243 ± 0.053	4.567ValThr: 4.567 ± 0.059	5.714ValVal: 5.714 ± 0.072	0.985ValTrp: 0.985 ± 0.029	1.47ValTyr: 1.47 ± 0.036	0.0ValXaa: 0.0 ± 0.0
Trp	1.353TrpAla: 1.353 ± 0.036	0.151TrpCys: 0.151 ± 0.012	0.764TrpAsp: 0.764 ± 0.024	0.64TrpGlu: 0.64 ± 0.024	0.553TrpPhe: 0.553 ± 0.021	1.045TrpGly: 1.045 ± 0.03	0.325TrpHis: 0.325 ± 0.015	0.765TrpIle: 0.765 ± 0.023	0.438TrpLys: 0.438 ± 0.015	1.644TrpLeu: 1.644 ± 0.037	0.409TrpMet: 0.409 ± 0.017	0.38TrpAsn: 0.38 ± 0.018	0.758TrpPro: 0.758 ± 0.025	0.601TrpGln: 0.601 ± 0.023	1.169TrpArg: 1.169 ± 0.028	0.882TrpSer: 0.882 ± 0.027	0.928TrpThr: 0.928 ± 0.029	0.865TrpVal: 0.865 ± 0.03	0.226TrpTrp: 0.226 ± 0.014	0.267TrpTyr: 0.267 ± 0.014	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.472TyrAla: 2.472 ± 0.044	0.237TyrCys: 0.237 ± 0.014	1.606TyrAsp: 1.606 ± 0.036	1.219TyrGlu: 1.219 ± 0.032	0.833TyrPhe: 0.833 ± 0.026	2.016TyrGly: 2.016 ± 0.038	0.47TyrHis: 0.47 ± 0.019	0.9TyrIle: 0.9 ± 0.024	0.448TyrLys: 0.448 ± 0.018	2.125TyrLeu: 2.125 ± 0.038	0.416TyrMet: 0.416 ± 0.021	0.516TyrAsn: 0.516 ± 0.02	1.062TyrPro: 1.062 ± 0.029	0.644TyrGln: 0.644 ± 0.022	1.64TyrArg: 1.64 ± 0.039	1.094TyrSer: 1.094 ± 0.029	1.091TyrThr: 1.091 ± 0.033	1.479TyrVal: 1.479 ± 0.034	0.351TyrTrp: 0.351 ± 0.016	0.563TyrTyr: 0.563 ± 0.024	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4308 proteins (1309259 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---