Amino acid dipepetide frequency for Tortoise microvirus 74

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
6.427AlaAla: 6.427 ± 2.566
1.071AlaCys: 1.071 ± 0.958
5.892AlaAsp: 5.892 ± 2.302
6.963AlaGlu: 6.963 ± 1.769
1.607AlaPhe: 1.607 ± 1.198
11.248AlaGly: 11.248 ± 2.669
4.285AlaHis: 4.285 ± 2.327
1.071AlaIle: 1.071 ± 0.881
5.892AlaLys: 5.892 ± 1.328
3.749AlaLeu: 3.749 ± 2.039
2.142AlaMet: 2.142 ± 0.666
4.821AlaAsn: 4.821 ± 1.76
3.749AlaPro: 3.749 ± 0.823
1.607AlaGln: 1.607 ± 1.06
3.749AlaArg: 3.749 ± 1.737
4.285AlaSer: 4.285 ± 1.897
3.214AlaThr: 3.214 ± 0.802
6.427AlaVal: 6.427 ± 1.748
3.749AlaTrp: 3.749 ± 1.9
2.142AlaTyr: 2.142 ± 0.879
0.0AlaXaa: 0.0 ± 0.0
Cys
1.607CysAla: 1.607 ± 0.779
0.536CysCys: 0.536 ± 0.479
0.536CysAsp: 0.536 ± 0.479
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
0.0CysHis: 0.0 ± 0.0
0.536CysIle: 0.536 ± 0.679
1.607CysLys: 1.607 ± 1.024
0.536CysLeu: 0.536 ± 0.479
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.071CysPro: 1.071 ± 0.769
1.071CysGln: 1.071 ± 0.958
1.071CysArg: 1.071 ± 0.466
0.536CysSer: 0.536 ± 0.479
0.0CysThr: 0.0 ± 0.0
1.071CysVal: 1.071 ± 0.799
0.0CysTrp: 0.0 ± 0.0
0.536CysTyr: 0.536 ± 0.479
0.0CysXaa: 0.0 ± 0.0
Asp
4.285AspAla: 4.285 ± 0.802
1.071AspCys: 1.071 ± 0.769
4.285AspAsp: 4.285 ± 1.059
3.749AspGlu: 3.749 ± 1.745
2.678AspPhe: 2.678 ± 0.685
6.427AspGly: 6.427 ± 1.176
1.071AspHis: 1.071 ± 0.812
1.071AspIle: 1.071 ± 0.466
1.607AspLys: 1.607 ± 0.843
3.214AspLeu: 3.214 ± 1.806
0.536AspMet: 0.536 ± 0.399
1.071AspAsn: 1.071 ± 0.666
5.892AspPro: 5.892 ± 0.996
3.214AspGln: 3.214 ± 1.28
3.214AspArg: 3.214 ± 1.542
5.356AspSer: 5.356 ± 1.427
2.678AspThr: 2.678 ± 1.184
4.821AspVal: 4.821 ± 1.795
3.749AspTrp: 3.749 ± 1.778
2.678AspTyr: 2.678 ± 1.448
0.0AspXaa: 0.0 ± 0.0
Glu
4.821GluAla: 4.821 ± 2.267
1.071GluCys: 1.071 ± 0.769
0.536GluAsp: 0.536 ± 0.399
3.749GluGlu: 3.749 ± 1.053
2.678GluPhe: 2.678 ± 1.351
5.356GluGly: 5.356 ± 1.351
1.071GluHis: 1.071 ± 0.799
1.071GluIle: 1.071 ± 0.657
3.214GluLys: 3.214 ± 1.398
3.214GluLeu: 3.214 ± 1.907
2.678GluMet: 2.678 ± 1.487
1.607GluAsn: 1.607 ± 0.878
4.285GluPro: 4.285 ± 1.703
4.821GluGln: 4.821 ± 1.921
5.892GluArg: 5.892 ± 1.771
2.142GluSer: 2.142 ± 0.95
4.285GluThr: 4.285 ± 1.035
8.57GluVal: 8.57 ± 3.132
3.214GluTrp: 3.214 ± 2.307
1.607GluTyr: 1.607 ± 1.024
0.0GluXaa: 0.0 ± 0.0
Phe
4.285PheAla: 4.285 ± 0.993
0.536PheCys: 0.536 ± 0.479
2.142PheAsp: 2.142 ± 0.935
2.142PheGlu: 2.142 ± 0.932
1.071PhePhe: 1.071 ± 0.466
2.678PheGly: 2.678 ± 1.149
1.607PheHis: 1.607 ± 1.198
2.142PheIle: 2.142 ± 1.073
0.536PheLys: 0.536 ± 0.913
2.678PheLeu: 2.678 ± 0.79
0.0PheMet: 0.0 ± 0.0
1.607PheAsn: 1.607 ± 1.108
2.678PhePro: 2.678 ± 0.947
0.536PheGln: 0.536 ± 0.399
1.607PheArg: 1.607 ± 1.32
1.607PheSer: 1.607 ± 0.551
2.142PheThr: 2.142 ± 0.87
1.607PheVal: 1.607 ± 0.857
0.536PheTrp: 0.536 ± 0.399
0.536PheTyr: 0.536 ± 0.679
0.0PheXaa: 0.0 ± 0.0
Gly
8.034GlyAla: 8.034 ± 2.722
0.536GlyCys: 0.536 ± 0.679
6.427GlyAsp: 6.427 ± 2.143
7.499GlyGlu: 7.499 ± 2.388
1.607GlyPhe: 1.607 ± 0.857
9.641GlyGly: 9.641 ± 5.574
3.749GlyHis: 3.749 ± 1.774
2.678GlyIle: 2.678 ± 1.227
6.427GlyLys: 6.427 ± 1.168
9.641GlyLeu: 9.641 ± 4.012
1.607GlyMet: 1.607 ± 1.356
2.678GlyAsn: 2.678 ± 1.997
4.821GlyPro: 4.821 ± 2.654
3.749GlyGln: 3.749 ± 2.891
6.963GlyArg: 6.963 ± 3.039
5.892GlySer: 5.892 ± 4.26
7.499GlyThr: 7.499 ± 2.273
6.427GlyVal: 6.427 ± 3.091
2.678GlyTrp: 2.678 ± 0.751
1.607GlyTyr: 1.607 ± 0.724
0.0GlyXaa: 0.0 ± 0.0
His
2.142HisAla: 2.142 ± 0.972
0.536HisCys: 0.536 ± 0.679
2.142HisAsp: 2.142 ± 0.695
1.607HisGlu: 1.607 ± 0.745
1.071HisPhe: 1.071 ± 0.466
2.142HisGly: 2.142 ± 1.307
1.071HisHis: 1.071 ± 0.466
1.071HisIle: 1.071 ± 0.466
0.536HisLys: 0.536 ± 0.479
3.214HisLeu: 3.214 ± 1.395
0.536HisMet: 0.536 ± 0.399
2.142HisAsn: 2.142 ± 1.96
2.142HisPro: 2.142 ± 1.314
0.536HisGln: 0.536 ± 0.679
3.214HisArg: 3.214 ± 0.944
0.536HisSer: 0.536 ± 0.679
1.071HisThr: 1.071 ± 0.696
2.142HisVal: 2.142 ± 1.396
1.071HisTrp: 1.071 ± 0.725
0.536HisTyr: 0.536 ± 0.479
0.0HisXaa: 0.0 ± 0.0
Ile
2.142IleAla: 2.142 ± 0.972
0.0IleCys: 0.0 ± 0.0
2.678IleAsp: 2.678 ± 1.448
3.214IleGlu: 3.214 ± 1.491
0.0IlePhe: 0.0 ± 0.0
2.678IleGly: 2.678 ± 1.962
1.607IleHis: 1.607 ± 0.57
1.071IleIle: 1.071 ± 0.466
1.607IleLys: 1.607 ± 0.745
1.607IleLeu: 1.607 ± 0.885
0.0IleMet: 0.0 ± 0.0
1.071IleAsn: 1.071 ± 0.921
3.749IlePro: 3.749 ± 1.305
0.536IleGln: 0.536 ± 0.399
1.607IleArg: 1.607 ± 0.57
0.536IleSer: 0.536 ± 0.399
1.607IleThr: 1.607 ± 0.857
3.214IleVal: 3.214 ± 1.155
0.0IleTrp: 0.0 ± 0.0
1.071IleTyr: 1.071 ± 0.658
0.0IleXaa: 0.0 ± 0.0
Lys
3.749LysAla: 3.749 ± 1.937
0.0LysCys: 0.0 ± 0.0
3.749LysAsp: 3.749 ± 1.165
2.678LysGlu: 2.678 ± 1.525
3.214LysPhe: 3.214 ± 1.14
3.749LysGly: 3.749 ± 1.21
0.0LysHis: 0.0 ± 0.0
0.0LysIle: 0.0 ± 0.0
1.607LysLys: 1.607 ± 1.239
5.356LysLeu: 5.356 ± 1.88
1.071LysMet: 1.071 ± 1.06
2.142LysAsn: 2.142 ± 0.777
5.356LysPro: 5.356 ± 1.138
6.427LysGln: 6.427 ± 1.648
6.427LysArg: 6.427 ± 0.853
0.536LysSer: 0.536 ± 0.644
1.607LysThr: 1.607 ± 1.024
3.749LysVal: 3.749 ± 0.927
1.071LysTrp: 1.071 ± 0.881
2.678LysTyr: 2.678 ± 1.293
0.0LysXaa: 0.0 ± 0.0
Leu
9.106LeuAla: 9.106 ± 1.423
0.536LeuCys: 0.536 ± 0.479
5.356LeuAsp: 5.356 ± 1.694
4.285LeuGlu: 4.285 ± 1.346
1.071LeuPhe: 1.071 ± 0.725
5.892LeuGly: 5.892 ± 1.632
2.678LeuHis: 2.678 ± 0.909
3.214LeuIle: 3.214 ± 2.964
5.892LeuLys: 5.892 ± 1.967
4.821LeuLeu: 4.821 ± 2.623
2.142LeuMet: 2.142 ± 1.293
2.678LeuAsn: 2.678 ± 2.38
3.749LeuPro: 3.749 ± 1.053
3.749LeuGln: 3.749 ± 0.842
5.356LeuArg: 5.356 ± 1.958
2.678LeuSer: 2.678 ± 1.341
2.142LeuThr: 2.142 ± 0.777
2.142LeuVal: 2.142 ± 1.088
1.607LeuTrp: 1.607 ± 0.85
1.071LeuTyr: 1.071 ± 0.958
0.0LeuXaa: 0.0 ± 0.0
Met
2.142MetAla: 2.142 ± 2.138
0.536MetCys: 0.536 ± 0.399
0.536MetAsp: 0.536 ± 0.399
2.678MetGlu: 2.678 ± 1.273
1.071MetPhe: 1.071 ± 1.145
2.142MetGly: 2.142 ± 0.979
0.536MetHis: 0.536 ± 0.399
0.536MetIle: 0.536 ± 0.399
1.607MetLys: 1.607 ± 0.901
2.142MetLeu: 2.142 ± 1.073
0.0MetMet: 0.0 ± 0.0
1.071MetAsn: 1.071 ± 0.799
1.071MetPro: 1.071 ± 0.696
1.071MetGln: 1.071 ± 0.799
0.0MetArg: 0.0 ± 0.0
1.607MetSer: 1.607 ± 1.083
1.071MetThr: 1.071 ± 0.881
2.678MetVal: 2.678 ± 2.175
0.0MetTrp: 0.0 ± 0.0
0.0MetTyr: 0.0 ± 0.0
0.0MetXaa: 0.0 ± 0.0
Asn
2.142AsnAla: 2.142 ± 1.159
0.536AsnCys: 0.536 ± 0.399
4.285AsnAsp: 4.285 ± 1.263
1.071AsnGlu: 1.071 ± 0.466
0.0AsnPhe: 0.0 ± 0.0
6.427AsnGly: 6.427 ± 2.352
1.607AsnHis: 1.607 ± 0.724
1.071AsnIle: 1.071 ± 0.958
1.071AsnLys: 1.071 ± 0.725
2.678AsnLeu: 2.678 ± 1.305
0.0AsnMet: 0.0 ± 0.0
1.071AsnAsn: 1.071 ± 0.799
2.678AsnPro: 2.678 ± 1.574
0.0AsnGln: 0.0 ± 0.0
3.749AsnArg: 3.749 ± 1.356
1.071AsnSer: 1.071 ± 0.799
2.142AsnThr: 2.142 ± 0.979
2.142AsnVal: 2.142 ± 0.656
1.607AsnTrp: 1.607 ± 0.551
1.071AsnTyr: 1.071 ± 0.657
0.0AsnXaa: 0.0 ± 0.0
Pro
3.749ProAla: 3.749 ± 1.065
0.0ProCys: 0.0 ± 0.0
4.285ProAsp: 4.285 ± 1.313
4.285ProGlu: 4.285 ± 1.875
3.214ProPhe: 3.214 ± 1.497
6.427ProGly: 6.427 ± 2.769
2.142ProHis: 2.142 ± 0.666
2.142ProIle: 2.142 ± 0.932
5.356ProLys: 5.356 ± 2.099
5.892ProLeu: 5.892 ± 1.316
3.214ProMet: 3.214 ± 1.502
2.142ProAsn: 2.142 ± 1.426
2.678ProPro: 2.678 ± 1.242
1.607ProGln: 1.607 ± 0.857
3.749ProArg: 3.749 ± 1.337
2.678ProSer: 2.678 ± 1.15
4.285ProThr: 4.285 ± 1.581
5.892ProVal: 5.892 ± 1.869
0.536ProTrp: 0.536 ± 0.679
0.0ProTyr: 0.0 ± 0.0
0.0ProXaa: 0.0 ± 0.0
Gln
2.142GlnAla: 2.142 ± 0.669
0.0GlnCys: 0.0 ± 0.0
1.607GlnAsp: 1.607 ± 0.914
2.678GlnGlu: 2.678 ± 1.344
4.285GlnPhe: 4.285 ± 1.331
3.749GlnGly: 3.749 ± 1.189
2.142GlnHis: 2.142 ± 1.085
3.214GlnIle: 3.214 ± 1.116
0.536GlnLys: 0.536 ± 0.479
2.678GlnLeu: 2.678 ± 0.81
0.536GlnMet: 0.536 ± 0.679
1.071GlnAsn: 1.071 ± 0.466
2.142GlnPro: 2.142 ± 1.307
3.214GlnGln: 3.214 ± 1.227
6.427GlnArg: 6.427 ± 3.58
3.214GlnSer: 3.214 ± 1.448
3.214GlnThr: 3.214 ± 1.28
1.071GlnVal: 1.071 ± 0.466
0.0GlnTrp: 0.0 ± 0.0
1.071GlnTyr: 1.071 ± 0.666
0.0GlnXaa: 0.0 ± 0.0
Arg
5.356ArgAla: 5.356 ± 1.618
1.071ArgCys: 1.071 ± 0.725
4.821ArgAsp: 4.821 ± 2.484
4.821ArgGlu: 4.821 ± 1.804
3.214ArgPhe: 3.214 ± 1.791
4.285ArgGly: 4.285 ± 2.18
2.142ArgHis: 2.142 ± 1.524
3.214ArgIle: 3.214 ± 1.719
5.356ArgLys: 5.356 ± 1.75
3.749ArgLeu: 3.749 ± 1.174
1.071ArgMet: 1.071 ± 0.828
1.607ArgAsn: 1.607 ± 0.57
4.821ArgPro: 4.821 ± 1.916
5.892ArgGln: 5.892 ± 2.326
3.749ArgArg: 3.749 ± 1.998
3.749ArgSer: 3.749 ± 1.045
2.142ArgThr: 2.142 ± 1.424
2.678ArgVal: 2.678 ± 0.79
1.071ArgTrp: 1.071 ± 0.958
3.749ArgTyr: 3.749 ± 1.472
0.0ArgXaa: 0.0 ± 0.0
Ser
3.214SerAla: 3.214 ± 1.5
1.607SerCys: 1.607 ± 0.857
3.214SerAsp: 3.214 ± 1.066
2.678SerGlu: 2.678 ± 0.685
3.214SerPhe: 3.214 ± 1.459
6.963SerGly: 6.963 ± 4.052
0.536SerHis: 0.536 ± 0.399
0.536SerIle: 0.536 ± 0.913
4.285SerLys: 4.285 ± 1.582
3.214SerLeu: 3.214 ± 1.95
2.142SerMet: 2.142 ± 1.165
0.536SerAsn: 0.536 ± 0.399
2.678SerPro: 2.678 ± 1.216
1.607SerGln: 1.607 ± 0.551
3.214SerArg: 3.214 ± 1.327
1.607SerSer: 1.607 ± 0.814
2.142SerThr: 2.142 ± 1.159
4.285SerVal: 4.285 ± 2.447
0.536SerTrp: 0.536 ± 0.672
1.071SerTyr: 1.071 ± 0.658
0.0SerXaa: 0.0 ± 0.0
Thr
4.821ThrAla: 4.821 ± 1.325
0.0ThrCys: 0.0 ± 0.0
3.214ThrAsp: 3.214 ± 1.418
3.214ThrGlu: 3.214 ± 1.777
0.0ThrPhe: 0.0 ± 0.0
10.177ThrGly: 10.177 ± 2.046
1.071ThrHis: 1.071 ± 1.344
1.071ThrIle: 1.071 ± 0.658
2.142ThrLys: 2.142 ± 0.669
3.214ThrLeu: 3.214 ± 1.756
1.607ThrMet: 1.607 ± 1.078
0.0ThrAsn: 0.0 ± 0.0
3.214ThrPro: 3.214 ± 1.923
2.678ThrGln: 2.678 ± 1.574
2.142ThrArg: 2.142 ± 1.003
3.749ThrSer: 3.749 ± 1.226
1.071ThrThr: 1.071 ± 0.696
2.678ThrVal: 2.678 ± 1.62
0.536ThrTrp: 0.536 ± 0.672
1.071ThrTyr: 1.071 ± 0.958
0.0ThrXaa: 0.0 ± 0.0
Val
10.177ValAla: 10.177 ± 2.411
0.536ValCys: 0.536 ± 0.479
4.821ValAsp: 4.821 ± 2.659
4.285ValGlu: 4.285 ± 2.021
0.536ValPhe: 0.536 ± 0.399
5.892ValGly: 5.892 ± 1.828
0.536ValHis: 0.536 ± 0.479
2.678ValIle: 2.678 ± 0.947
4.285ValLys: 4.285 ± 1.622
4.821ValLeu: 4.821 ± 1.469
1.607ValMet: 1.607 ± 1.285
5.356ValAsn: 5.356 ± 1.645
2.678ValPro: 2.678 ± 1.448
1.607ValGln: 1.607 ± 0.551
4.285ValArg: 4.285 ± 1.914
5.356ValSer: 5.356 ± 3.214
3.749ValThr: 3.749 ± 1.579
6.427ValVal: 6.427 ± 2.683
1.071ValTrp: 1.071 ± 0.879
2.678ValTyr: 2.678 ± 0.768
0.0ValXaa: 0.0 ± 0.0
Trp
2.678TrpAla: 2.678 ± 1.177
0.536TrpCys: 0.536 ± 0.399
0.536TrpAsp: 0.536 ± 0.479
1.607TrpGlu: 1.607 ± 1.308
0.536TrpPhe: 0.536 ± 0.672
1.607TrpGly: 1.607 ± 0.882
1.071TrpHis: 1.071 ± 0.696
0.0TrpIle: 0.0 ± 0.0
1.071TrpLys: 1.071 ± 1.145
2.142TrpLeu: 2.142 ± 1.213
0.536TrpMet: 0.536 ± 0.672
1.071TrpAsn: 1.071 ± 0.725
2.678TrpPro: 2.678 ± 1.133
1.071TrpGln: 1.071 ± 0.975
1.071TrpArg: 1.071 ± 1.358
0.536TrpSer: 0.536 ± 0.672
1.607TrpThr: 1.607 ± 0.945
3.214TrpVal: 3.214 ± 1.351
2.142TrpTrp: 2.142 ± 1.053
0.536TrpTyr: 0.536 ± 0.399
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.071TyrAla: 1.071 ± 0.657
0.0TyrCys: 0.0 ± 0.0
1.607TyrAsp: 1.607 ± 0.891
2.678TyrGlu: 2.678 ± 1.351
1.607TyrPhe: 1.607 ± 0.724
2.678TyrGly: 2.678 ± 1.781
0.536TyrHis: 0.536 ± 0.672
1.607TyrIle: 1.607 ± 0.724
1.071TyrLys: 1.071 ± 0.769
1.607TyrLeu: 1.607 ± 0.745
0.536TyrMet: 0.536 ± 0.399
2.678TyrAsn: 2.678 ± 1.448
2.142TyrPro: 2.142 ± 1.154
0.0TyrGln: 0.0 ± 0.0
1.071TyrArg: 1.071 ± 0.725
1.607TyrSer: 1.607 ± 1.437
0.0TyrThr: 0.0 ± 0.0
2.142TyrVal: 2.142 ± 1.916
1.071TyrTrp: 1.071 ± 0.466
0.0TyrTyr: 0.0 ± 0.0
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 7 proteins (1868 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski