Amino acid dipepetide frequency for Hubei sobemo-like virus 42

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.212AlaAla: 7.212 ± 3.043
0.0AlaCys: 0.0 ± 0.0
3.606AlaAsp: 3.606 ± 2.38
3.606AlaGlu: 3.606 ± 0.663
1.202AlaPhe: 1.202 ± 0.923
1.202AlaGly: 1.202 ± 0.793
1.202AlaHis: 1.202 ± 0.923
0.0AlaIle: 0.0 ± 0.0
2.404AlaLys: 2.404 ± 1.847
9.615AlaLeu: 9.615 ± 4.63
0.0AlaMet: 0.0 ± 0.0
1.202AlaAsn: 1.202 ± 0.923
3.606AlaPro: 3.606 ± 0.663
2.404AlaGln: 2.404 ± 0.13
1.202AlaArg: 1.202 ± 0.793
8.413AlaSer: 8.413 ± 3.837
1.202AlaThr: 1.202 ± 0.793
4.808AlaVal: 4.808 ± 0.26
2.404AlaTrp: 2.404 ± 0.13
0.0AlaTyr: 0.0 ± 0.0
0.0AlaXaa: 0.0 ± 0.0
Cys
0.0CysAla: 0.0 ± 0.0
1.202CysCys: 1.202 ± 0.923
0.0CysAsp: 0.0 ± 0.0
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.0CysGly: 0.0 ± 0.0
2.404CysHis: 2.404 ± 1.587
0.0CysIle: 0.0 ± 0.0
1.202CysLys: 1.202 ± 0.793
1.202CysLeu: 1.202 ± 0.923
0.0CysMet: 0.0 ± 0.0
0.0CysAsn: 0.0 ± 0.0
1.202CysPro: 1.202 ± 0.923
1.202CysGln: 1.202 ± 0.923
1.202CysArg: 1.202 ± 0.793
0.0CysSer: 0.0 ± 0.0
0.0CysThr: 0.0 ± 0.0
1.202CysVal: 1.202 ± 0.923
0.0CysTrp: 0.0 ± 0.0
3.606CysTyr: 3.606 ± 2.77
0.0CysXaa: 0.0 ± 0.0
Asp
3.606AspAla: 3.606 ± 2.77
1.202AspCys: 1.202 ± 0.793
8.413AspAsp: 8.413 ± 1.313
2.404AspGlu: 2.404 ± 1.587
3.606AspPhe: 3.606 ± 2.38
6.01AspGly: 6.01 ± 1.183
1.202AspHis: 1.202 ± 0.923
0.0AspIle: 0.0 ± 0.0
3.606AspLys: 3.606 ± 1.053
2.404AspLeu: 2.404 ± 0.13
0.0AspMet: 0.0 ± 0.0
2.404AspAsn: 2.404 ± 1.847
2.404AspPro: 2.404 ± 0.13
2.404AspGln: 2.404 ± 1.587
3.606AspArg: 3.606 ± 0.663
1.202AspSer: 1.202 ± 0.923
2.404AspThr: 2.404 ± 0.13
3.606AspVal: 3.606 ± 0.663
2.404AspTrp: 2.404 ± 1.847
3.606AspTyr: 3.606 ± 0.663
0.0AspXaa: 0.0 ± 0.0
Glu
2.404GluAla: 2.404 ± 0.13
0.0GluCys: 0.0 ± 0.0
3.606GluAsp: 3.606 ± 0.663
3.606GluGlu: 3.606 ± 0.663
2.404GluPhe: 2.404 ± 1.847
0.0GluGly: 0.0 ± 0.0
3.606GluHis: 3.606 ± 1.053
1.202GluIle: 1.202 ± 0.793
2.404GluLys: 2.404 ± 1.587
10.817GluLeu: 10.817 ± 3.16
1.202GluMet: 1.202 ± 0.793
4.808GluAsn: 4.808 ± 0.26
3.606GluPro: 3.606 ± 1.053
2.404GluGln: 2.404 ± 0.13
1.202GluArg: 1.202 ± 0.923
7.212GluSer: 7.212 ± 1.327
3.606GluThr: 3.606 ± 0.663
1.202GluVal: 1.202 ± 0.793
2.404GluTrp: 2.404 ± 1.847
2.404GluTyr: 2.404 ± 0.13
0.0GluXaa: 0.0 ± 0.0
Phe
3.606PheAla: 3.606 ± 0.663
1.202PheCys: 1.202 ± 0.923
3.606PheAsp: 3.606 ± 1.053
1.202PheGlu: 1.202 ± 0.793
1.202PhePhe: 1.202 ± 0.923
6.01PheGly: 6.01 ± 1.183
2.404PheHis: 2.404 ± 1.587
2.404PheIle: 2.404 ± 0.13
1.202PheLys: 1.202 ± 0.793
7.212PheLeu: 7.212 ± 0.39
0.0PheMet: 0.0 ± 0.0
1.202PheAsn: 1.202 ± 0.923
2.404PhePro: 2.404 ± 1.587
0.0PheGln: 0.0 ± 0.0
3.606PheArg: 3.606 ± 0.663
6.01PheSer: 6.01 ± 4.617
0.0PheThr: 0.0 ± 0.0
1.202PheVal: 1.202 ± 0.793
1.202PheTrp: 1.202 ± 0.793
1.202PheTyr: 1.202 ± 0.923
0.0PheXaa: 0.0 ± 0.0
Gly
6.01GlyAla: 6.01 ± 3.967
1.202GlyCys: 1.202 ± 0.923
2.404GlyAsp: 2.404 ± 1.847
2.404GlyGlu: 2.404 ± 1.587
2.404GlyPhe: 2.404 ± 1.847
6.01GlyGly: 6.01 ± 0.533
0.0GlyHis: 0.0 ± 0.0
7.212GlyIle: 7.212 ± 1.327
3.606GlyLys: 3.606 ± 2.38
0.0GlyLeu: 0.0 ± 0.0
2.404GlyMet: 2.404 ± 1.847
2.404GlyAsn: 2.404 ± 1.587
1.202GlyPro: 1.202 ± 0.923
0.0GlyGln: 0.0 ± 0.0
3.606GlyArg: 3.606 ± 1.053
7.212GlySer: 7.212 ± 3.043
3.606GlyThr: 3.606 ± 2.38
3.606GlyVal: 3.606 ± 0.663
4.808GlyTrp: 4.808 ± 0.26
3.606GlyTyr: 3.606 ± 0.663
0.0GlyXaa: 0.0 ± 0.0
His
2.404HisAla: 2.404 ± 0.13
0.0HisCys: 0.0 ± 0.0
0.0HisAsp: 0.0 ± 0.0
0.0HisGlu: 0.0 ± 0.0
0.0HisPhe: 0.0 ± 0.0
1.202HisGly: 1.202 ± 0.793
0.0HisHis: 0.0 ± 0.0
1.202HisIle: 1.202 ± 0.923
2.404HisLys: 2.404 ± 0.13
3.606HisLeu: 3.606 ± 1.053
3.606HisMet: 3.606 ± 2.35
0.0HisAsn: 0.0 ± 0.0
1.202HisPro: 1.202 ± 0.793
0.0HisGln: 0.0 ± 0.0
0.0HisArg: 0.0 ± 0.0
1.202HisSer: 1.202 ± 0.923
1.202HisThr: 1.202 ± 0.923
2.404HisVal: 2.404 ± 1.587
0.0HisTrp: 0.0 ± 0.0
2.404HisTyr: 2.404 ± 1.847
0.0HisXaa: 0.0 ± 0.0
Ile
1.202IleAla: 1.202 ± 0.793
1.202IleCys: 1.202 ± 0.793
0.0IleAsp: 0.0 ± 0.0
2.404IleGlu: 2.404 ± 1.847
1.202IlePhe: 1.202 ± 0.923
3.606IleGly: 3.606 ± 0.663
2.404IleHis: 2.404 ± 0.13
1.202IleIle: 1.202 ± 0.923
4.808IleLys: 4.808 ± 1.977
8.413IleLeu: 8.413 ± 1.313
0.0IleMet: 0.0 ± 0.0
3.606IleAsn: 3.606 ± 0.663
1.202IlePro: 1.202 ± 0.923
1.202IleGln: 1.202 ± 0.923
1.202IleArg: 1.202 ± 0.793
4.808IleSer: 4.808 ± 0.26
3.606IleThr: 3.606 ± 0.663
1.202IleVal: 1.202 ± 0.793
0.0IleTrp: 0.0 ± 0.0
2.404IleTyr: 2.404 ± 0.13
0.0IleXaa: 0.0 ± 0.0
Lys
0.0LysAla: 0.0 ± 0.0
0.0LysCys: 0.0 ± 0.0
3.606LysAsp: 3.606 ± 2.38
2.404LysGlu: 2.404 ± 0.13
2.404LysPhe: 2.404 ± 0.13
3.606LysGly: 3.606 ± 0.663
2.404LysHis: 2.404 ± 0.13
1.202LysIle: 1.202 ± 0.793
1.202LysLys: 1.202 ± 0.793
4.808LysLeu: 4.808 ± 0.26
2.404LysMet: 2.404 ± 0.13
3.606LysAsn: 3.606 ± 1.053
2.404LysPro: 2.404 ± 1.587
2.404LysGln: 2.404 ± 0.13
6.01LysArg: 6.01 ± 0.533
3.606LysSer: 3.606 ± 2.77
4.808LysThr: 4.808 ± 0.26
8.413LysVal: 8.413 ± 0.403
0.0LysTrp: 0.0 ± 0.0
1.202LysTyr: 1.202 ± 0.923
0.0LysXaa: 0.0 ± 0.0
Leu
3.606LeuAla: 3.606 ± 2.38
1.202LeuCys: 1.202 ± 0.923
3.606LeuAsp: 3.606 ± 2.77
6.01LeuGlu: 6.01 ± 2.9
6.01LeuPhe: 6.01 ± 1.183
9.615LeuGly: 9.615 ± 1.197
2.404LeuHis: 2.404 ± 1.847
4.808LeuIle: 4.808 ± 1.977
6.01LeuLys: 6.01 ± 0.533
4.808LeuLeu: 4.808 ± 1.457
2.404LeuMet: 2.404 ± 0.13
1.202LeuAsn: 1.202 ± 0.793
1.202LeuPro: 1.202 ± 0.923
3.606LeuGln: 3.606 ± 0.663
3.606LeuArg: 3.606 ± 0.663
4.808LeuSer: 4.808 ± 1.457
7.212LeuThr: 7.212 ± 0.39
6.01LeuVal: 6.01 ± 3.967
2.404LeuTrp: 2.404 ± 1.847
7.212LeuTyr: 7.212 ± 0.39
0.0LeuXaa: 0.0 ± 0.0
Met
2.404MetAla: 2.404 ± 1.587
0.0MetCys: 0.0 ± 0.0
4.808MetAsp: 4.808 ± 0.26
4.808MetGlu: 4.808 ± 0.26
2.404MetPhe: 2.404 ± 0.13
1.202MetGly: 1.202 ± 0.793
0.0MetHis: 0.0 ± 0.0
1.202MetIle: 1.202 ± 0.923
1.202MetLys: 1.202 ± 0.923
2.404MetLeu: 2.404 ± 1.847
0.0MetMet: 0.0 ± 0.0
1.202MetAsn: 1.202 ± 0.923
0.0MetPro: 0.0 ± 0.0
0.0MetGln: 0.0 ± 0.0
1.202MetArg: 1.202 ± 0.923
2.404MetSer: 2.404 ± 0.13
0.0MetThr: 0.0 ± 0.0
4.808MetVal: 4.808 ± 1.977
0.0MetTrp: 0.0 ± 0.0
3.606MetTyr: 3.606 ± 2.77
0.0MetXaa: 0.0 ± 0.0
Asn
4.808AsnAla: 4.808 ± 1.457
0.0AsnCys: 0.0 ± 0.0
1.202AsnAsp: 1.202 ± 0.923
3.606AsnGlu: 3.606 ± 2.77
4.808AsnPhe: 4.808 ± 1.977
2.404AsnGly: 2.404 ± 1.587
0.0AsnHis: 0.0 ± 0.0
1.202AsnIle: 1.202 ± 0.923
3.606AsnLys: 3.606 ± 1.053
3.606AsnLeu: 3.606 ± 2.38
1.202AsnMet: 1.202 ± 0.793
1.202AsnAsn: 1.202 ± 0.793
1.202AsnPro: 1.202 ± 0.923
1.202AsnGln: 1.202 ± 0.793
1.202AsnArg: 1.202 ± 0.923
3.606AsnSer: 3.606 ± 0.663
2.404AsnThr: 2.404 ± 0.13
4.808AsnVal: 4.808 ± 0.26
1.202AsnTrp: 1.202 ± 0.923
0.0AsnTyr: 0.0 ± 0.0
0.0AsnXaa: 0.0 ± 0.0
Pro
0.0ProAla: 0.0 ± 0.0
0.0ProCys: 0.0 ± 0.0
3.606ProAsp: 3.606 ± 0.663
2.404ProGlu: 2.404 ± 1.587
1.202ProPhe: 1.202 ± 0.923
3.606ProGly: 3.606 ± 1.053
1.202ProHis: 1.202 ± 0.923
0.0ProIle: 0.0 ± 0.0
2.404ProLys: 2.404 ± 0.13
2.404ProLeu: 2.404 ± 0.13
3.606ProMet: 3.606 ± 1.053
0.0ProAsn: 0.0 ± 0.0
0.0ProPro: 0.0 ± 0.0
2.404ProGln: 2.404 ± 1.847
3.606ProArg: 3.606 ± 0.663
2.404ProSer: 2.404 ± 0.13
3.606ProThr: 3.606 ± 0.663
1.202ProVal: 1.202 ± 0.793
0.0ProTrp: 0.0 ± 0.0
1.202ProTyr: 1.202 ± 0.923
0.0ProXaa: 0.0 ± 0.0
Gln
2.404GlnAla: 2.404 ± 1.847
1.202GlnCys: 1.202 ± 0.923
0.0GlnAsp: 0.0 ± 0.0
1.202GlnGlu: 1.202 ± 0.793
0.0GlnPhe: 0.0 ± 0.0
3.606GlnGly: 3.606 ± 0.663
0.0GlnHis: 0.0 ± 0.0
1.202GlnIle: 1.202 ± 0.923
0.0GlnLys: 0.0 ± 0.0
4.808GlnLeu: 4.808 ± 1.457
2.404GlnMet: 2.404 ± 1.502
0.0GlnAsn: 0.0 ± 0.0
0.0GlnPro: 0.0 ± 0.0
2.404GlnGln: 2.404 ± 1.587
4.808GlnArg: 4.808 ± 1.457
0.0GlnSer: 0.0 ± 0.0
1.202GlnThr: 1.202 ± 0.793
3.606GlnVal: 3.606 ± 1.053
1.202GlnTrp: 1.202 ± 0.793
1.202GlnTyr: 1.202 ± 0.923
0.0GlnXaa: 0.0 ± 0.0
Arg
2.404ArgAla: 2.404 ± 1.587
2.404ArgCys: 2.404 ± 1.847
2.404ArgAsp: 2.404 ± 0.13
8.413ArgGlu: 8.413 ± 3.03
7.212ArgPhe: 7.212 ± 3.043
1.202ArgGly: 1.202 ± 0.793
0.0ArgHis: 0.0 ± 0.0
3.606ArgIle: 3.606 ± 1.053
4.808ArgLys: 4.808 ± 1.457
6.01ArgLeu: 6.01 ± 1.183
0.0ArgMet: 0.0 ± 0.0
1.202ArgAsn: 1.202 ± 0.793
3.606ArgPro: 3.606 ± 0.663
1.202ArgGln: 1.202 ± 0.923
2.404ArgArg: 2.404 ± 1.847
1.202ArgSer: 1.202 ± 0.793
3.606ArgThr: 3.606 ± 0.663
1.202ArgVal: 1.202 ± 0.923
3.606ArgTrp: 3.606 ± 1.053
3.606ArgTyr: 3.606 ± 2.38
0.0ArgXaa: 0.0 ± 0.0
Ser
0.0SerAla: 0.0 ± 0.0
0.0SerCys: 0.0 ± 0.0
3.606SerAsp: 3.606 ± 0.663
7.212SerGlu: 7.212 ± 0.39
2.404SerPhe: 2.404 ± 0.13
8.413SerGly: 8.413 ± 3.837
0.0SerHis: 0.0 ± 0.0
6.01SerIle: 6.01 ± 0.533
6.01SerLys: 6.01 ± 0.533
2.404SerLeu: 2.404 ± 0.13
3.606SerMet: 3.606 ± 1.053
4.808SerAsn: 4.808 ± 0.26
4.808SerPro: 4.808 ± 0.26
4.808SerGln: 4.808 ± 3.173
6.01SerArg: 6.01 ± 1.183
14.423SerSer: 14.423 ± 4.37
1.202SerThr: 1.202 ± 0.793
9.615SerVal: 9.615 ± 1.197
3.606SerTrp: 3.606 ± 2.38
2.404SerTyr: 2.404 ± 0.13
0.0SerXaa: 0.0 ± 0.0
Thr
8.413ThrAla: 8.413 ± 0.403
2.404ThrCys: 2.404 ± 1.587
1.202ThrAsp: 1.202 ± 0.923
3.606ThrGlu: 3.606 ± 2.38
0.0ThrPhe: 0.0 ± 0.0
0.0ThrGly: 0.0 ± 0.0
0.0ThrHis: 0.0 ± 0.0
3.606ThrIle: 3.606 ± 2.77
2.404ThrLys: 2.404 ± 1.587
3.606ThrLeu: 3.606 ± 1.053
2.404ThrMet: 2.404 ± 1.587
0.0ThrAsn: 0.0 ± 0.0
1.202ThrPro: 1.202 ± 0.923
1.202ThrGln: 1.202 ± 0.923
2.404ThrArg: 2.404 ± 0.13
8.413ThrSer: 8.413 ± 3.837
1.202ThrThr: 1.202 ± 0.793
1.202ThrVal: 1.202 ± 0.793
2.404ThrTrp: 2.404 ± 1.587
0.0ThrTyr: 0.0 ± 0.0
0.0ThrXaa: 0.0 ± 0.0
Val
1.202ValAla: 1.202 ± 0.923
1.202ValCys: 1.202 ± 0.923
6.01ValAsp: 6.01 ± 0.533
1.202ValGlu: 1.202 ± 0.793
4.808ValPhe: 4.808 ± 1.457
3.606ValGly: 3.606 ± 0.663
1.202ValHis: 1.202 ± 0.923
3.606ValIle: 3.606 ± 0.663
2.404ValLys: 2.404 ± 1.587
4.808ValLeu: 4.808 ± 0.26
2.404ValMet: 2.404 ± 1.847
6.01ValAsn: 6.01 ± 1.183
1.202ValPro: 1.202 ± 0.793
3.606ValGln: 3.606 ± 1.053
8.413ValArg: 8.413 ± 2.12
7.212ValSer: 7.212 ± 1.327
2.404ValThr: 2.404 ± 1.587
9.615ValVal: 9.615 ± 1.197
0.0ValTrp: 0.0 ± 0.0
3.606ValTyr: 3.606 ± 0.663
0.0ValXaa: 0.0 ± 0.0
Trp
1.202TrpAla: 1.202 ± 0.793
0.0TrpCys: 0.0 ± 0.0
2.404TrpAsp: 2.404 ± 0.13
0.0TrpGlu: 0.0 ± 0.0
3.606TrpPhe: 3.606 ± 0.663
0.0TrpGly: 0.0 ± 0.0
2.404TrpHis: 2.404 ± 1.847
3.606TrpIle: 3.606 ± 0.663
2.404TrpLys: 2.404 ± 1.847
2.404TrpLeu: 2.404 ± 0.13
3.606TrpMet: 3.606 ± 2.77
4.808TrpAsn: 4.808 ± 1.457
0.0TrpPro: 0.0 ± 0.0
0.0TrpGln: 0.0 ± 0.0
2.404TrpArg: 2.404 ± 0.13
1.202TrpSer: 1.202 ± 0.793
1.202TrpThr: 1.202 ± 0.923
0.0TrpVal: 0.0 ± 0.0
0.0TrpTrp: 0.0 ± 0.0
0.0TrpTyr: 0.0 ± 0.0
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.404TyrAla: 2.404 ± 1.587
0.0TyrCys: 0.0 ± 0.0
2.404TyrAsp: 2.404 ± 1.847
3.606TyrGlu: 3.606 ± 2.77
0.0TyrPhe: 0.0 ± 0.0
2.404TyrGly: 2.404 ± 0.13
0.0TyrHis: 0.0 ± 0.0
2.404TyrIle: 2.404 ± 1.587
2.404TyrLys: 2.404 ± 1.847
2.404TyrLeu: 2.404 ± 0.13
1.202TyrMet: 1.202 ± 0.793
3.606TyrAsn: 3.606 ± 1.053
2.404TyrPro: 2.404 ± 1.847
0.0TyrGln: 0.0 ± 0.0
2.404TyrArg: 2.404 ± 1.847
6.01TyrSer: 6.01 ± 2.25
1.202TyrThr: 1.202 ± 0.793
4.808TyrVal: 4.808 ± 1.977
3.606TyrTrp: 3.606 ± 1.053
1.202TyrTyr: 1.202 ± 0.923
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (833 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski