Amino acid dipepetide frequency for Wenzhou shrimp virus 9

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
7.752AlaAla: 7.752 ± 2.576
2.114AlaCys: 2.114 ± 1.158
6.342AlaAsp: 6.342 ± 0.987
2.114AlaGlu: 2.114 ± 1.361
1.409AlaPhe: 1.409 ± 1.4
8.457AlaGly: 8.457 ± 0.971
0.705AlaHis: 0.705 ± 0.7
3.524AlaIle: 3.524 ± 0.386
2.819AlaLys: 2.819 ± 0.336
5.638AlaLeu: 5.638 ± 1.399
2.114AlaMet: 2.114 ± 1.198
1.409AlaAsn: 1.409 ± 0.782
4.228AlaPro: 4.228 ± 1.314
2.819AlaGln: 2.819 ± 0.336
3.524AlaArg: 3.524 ± 0.879
8.457AlaSer: 8.457 ± 0.219
3.524AlaThr: 3.524 ± 0.655
4.933AlaVal: 4.933 ± 1.135
0.705AlaTrp: 0.705 ± 0.7
2.819AlaTyr: 2.819 ± 0.699
0.0AlaXaa: 0.0 ± 0.0
Cys
1.409CysAla: 1.409 ± 1.185
0.0CysCys: 0.0 ± 0.0
0.705CysAsp: 0.705 ± 0.551
0.0CysGlu: 0.0 ± 0.0
0.0CysPhe: 0.0 ± 0.0
0.705CysGly: 0.705 ± 0.7
0.705CysHis: 0.705 ± 0.551
0.705CysIle: 0.705 ± 0.7
2.114CysLys: 2.114 ± 0.883
2.114CysLeu: 2.114 ± 0.883
0.0CysMet: 0.0 ± 0.0
0.705CysAsn: 0.705 ± 0.7
2.114CysPro: 2.114 ± 0.881
0.0CysGln: 0.0 ± 0.0
3.524CysArg: 3.524 ± 1.019
1.409CysSer: 1.409 ± 1.101
0.705CysThr: 0.705 ± 0.551
0.705CysVal: 0.705 ± 0.593
0.705CysTrp: 0.705 ± 0.7
0.0CysTyr: 0.0 ± 0.0
0.0CysXaa: 0.0 ± 0.0
Asp
2.819AspAla: 2.819 ± 0.915
0.705AspCys: 0.705 ± 0.7
4.228AspAsp: 4.228 ± 0.793
4.933AspGlu: 4.933 ± 0.201
2.114AspPhe: 2.114 ± 0.243
4.228AspGly: 4.228 ± 1.919
1.409AspHis: 1.409 ± 0.576
2.114AspIle: 2.114 ± 0.243
2.819AspLys: 2.819 ± 0.699
7.047AspLeu: 7.047 ± 1.073
0.705AspMet: 0.705 ± 0.443
0.705AspAsn: 0.705 ± 0.551
2.114AspPro: 2.114 ± 0.96
0.705AspGln: 0.705 ± 0.7
2.819AspArg: 2.819 ± 0.336
3.524AspSer: 3.524 ± 1.019
4.228AspThr: 4.228 ± 0.942
2.114AspVal: 2.114 ± 0.881
1.409AspTrp: 1.409 ± 0.782
2.114AspTyr: 2.114 ± 0.881
0.0AspXaa: 0.0 ± 0.0
Glu
3.524GluAla: 3.524 ± 1.689
0.0GluCys: 0.0 ± 0.0
1.409GluAsp: 1.409 ± 0.511
7.752GluGlu: 7.752 ± 0.529
3.524GluPhe: 3.524 ± 1.689
3.524GluGly: 3.524 ± 1.611
1.409GluHis: 1.409 ± 1.4
1.409GluIle: 1.409 ± 0.576
1.409GluLys: 1.409 ± 0.576
6.342GluLeu: 6.342 ± 0.987
1.409GluMet: 1.409 ± 0.511
2.819GluAsn: 2.819 ± 1.378
2.819GluPro: 2.819 ± 0.699
0.705GluGln: 0.705 ± 0.551
4.933GluArg: 4.933 ± 1.21
5.638GluSer: 5.638 ± 2.042
2.114GluThr: 2.114 ± 0.881
7.752GluVal: 7.752 ± 1.424
0.705GluTrp: 0.705 ± 0.7
1.409GluTyr: 1.409 ± 1.101
0.0GluXaa: 0.0 ± 0.0
Phe
4.228PheAla: 4.228 ± 1.314
0.705PheCys: 0.705 ± 0.551
2.819PheAsp: 2.819 ± 1.824
3.524PheGlu: 3.524 ± 0.655
1.409PhePhe: 1.409 ± 0.782
3.524PheGly: 3.524 ± 0.386
2.114PheHis: 2.114 ± 0.243
1.409PheIle: 1.409 ± 1.101
1.409PheLys: 1.409 ± 0.782
3.524PheLeu: 3.524 ± 1.019
1.409PheMet: 1.409 ± 1.4
0.705PheAsn: 0.705 ± 0.7
2.819PhePro: 2.819 ± 1.378
0.705PheGln: 0.705 ± 0.593
3.524PheArg: 3.524 ± 1.331
2.819PheSer: 2.819 ± 1.354
2.114PheThr: 2.114 ± 0.883
1.409PheVal: 1.409 ± 1.4
0.0PheTrp: 0.0 ± 0.0
1.409PheTyr: 1.409 ± 0.511
0.0PheXaa: 0.0 ± 0.0
Gly
5.638GlyAla: 5.638 ± 2.115
2.114GlyCys: 2.114 ± 0.243
3.524GlyAsp: 3.524 ± 1.274
4.933GlyGlu: 4.933 ± 2.001
4.228GlyPhe: 4.228 ± 1.393
2.819GlyGly: 2.819 ± 1.021
2.114GlyHis: 2.114 ± 1.361
1.409GlyIle: 1.409 ± 0.576
2.819GlyLys: 2.819 ± 1.021
5.638GlyLeu: 5.638 ± 2.115
0.705GlyMet: 0.705 ± 0.593
1.409GlyAsn: 1.409 ± 0.511
3.524GlyPro: 3.524 ± 1.418
2.819GlyGln: 2.819 ± 0.915
2.819GlyArg: 2.819 ± 0.336
5.638GlySer: 5.638 ± 2.529
3.524GlyThr: 3.524 ± 1.331
4.933GlyVal: 4.933 ± 2.906
1.409GlyTrp: 1.409 ± 1.4
3.524GlyTyr: 3.524 ± 0.655
0.0GlyXaa: 0.0 ± 0.0
His
1.409HisAla: 1.409 ± 0.782
0.0HisCys: 0.0 ± 0.0
0.705HisAsp: 0.705 ± 0.551
1.409HisGlu: 1.409 ± 1.101
1.409HisPhe: 1.409 ± 1.101
1.409HisGly: 1.409 ± 0.576
2.114HisHis: 2.114 ± 0.883
2.114HisIle: 2.114 ± 1.158
0.705HisLys: 0.705 ± 0.551
3.524HisLeu: 3.524 ± 1.274
2.114HisMet: 2.114 ± 1.342
0.705HisAsn: 0.705 ± 0.7
0.705HisPro: 0.705 ± 0.7
0.0HisGln: 0.0 ± 0.0
2.114HisArg: 2.114 ± 0.243
2.114HisSer: 2.114 ± 0.243
2.114HisThr: 2.114 ± 1.198
0.705HisVal: 0.705 ± 0.551
1.409HisTrp: 1.409 ± 0.511
2.114HisTyr: 2.114 ± 1.158
0.0HisXaa: 0.0 ± 0.0
Ile
2.114IleAla: 2.114 ± 0.243
0.705IleCys: 0.705 ± 0.551
2.114IleAsp: 2.114 ± 0.243
2.114IleGlu: 2.114 ± 0.243
0.705IlePhe: 0.705 ± 0.7
2.819IleGly: 2.819 ± 1.721
0.705IleHis: 0.705 ± 0.593
0.0IleIle: 0.0 ± 0.0
1.409IleLys: 1.409 ± 0.511
5.638IleLeu: 5.638 ± 2.926
2.114IleMet: 2.114 ± 0.773
0.705IleAsn: 0.705 ± 0.551
2.819IlePro: 2.819 ± 0.336
0.705IleGln: 0.705 ± 0.7
2.114IleArg: 2.114 ± 0.243
3.524IleSer: 3.524 ± 0.879
2.819IleThr: 2.819 ± 0.336
3.524IleVal: 3.524 ± 0.655
0.0IleTrp: 0.0 ± 0.0
2.114IleTyr: 2.114 ± 0.243
0.0IleXaa: 0.0 ± 0.0
Lys
3.524LysAla: 3.524 ± 1.385
0.0LysCys: 0.0 ± 0.0
1.409LysAsp: 1.409 ± 0.576
1.409LysGlu: 1.409 ± 0.511
0.705LysPhe: 0.705 ± 0.551
1.409LysGly: 1.409 ± 0.511
1.409LysHis: 1.409 ± 0.782
1.409LysIle: 1.409 ± 0.782
4.933LysLys: 4.933 ± 1.883
3.524LysLeu: 3.524 ± 1.935
1.409LysMet: 1.409 ± 1.4
2.819LysAsn: 2.819 ± 1.721
0.705LysPro: 0.705 ± 0.551
1.409LysGln: 1.409 ± 0.511
4.933LysArg: 4.933 ± 1.197
7.752LysSer: 7.752 ± 3.158
3.524LysThr: 3.524 ± 1.331
2.114LysVal: 2.114 ± 1.778
0.0LysTrp: 0.0 ± 0.0
2.819LysTyr: 2.819 ± 1.021
0.0LysXaa: 0.0 ± 0.0
Leu
11.98LeuAla: 11.98 ± 3.749
2.819LeuCys: 2.819 ± 0.699
4.933LeuAsp: 4.933 ± 1.8
7.752LeuGlu: 7.752 ± 1.498
2.114LeuPhe: 2.114 ± 0.883
2.819LeuGly: 2.819 ± 0.915
3.524LeuHis: 3.524 ± 0.655
2.819LeuIle: 2.819 ± 0.915
6.342LeuLys: 6.342 ± 2.399
7.047LeuLeu: 7.047 ± 0.293
1.409LeuMet: 1.409 ± 1.101
1.409LeuAsn: 1.409 ± 0.511
4.933LeuPro: 4.933 ± 0.201
4.228LeuGln: 4.228 ± 0.486
3.524LeuArg: 3.524 ± 1.689
7.047LeuSer: 7.047 ± 1.579
6.342LeuThr: 6.342 ± 2.307
4.933LeuVal: 4.933 ± 2.461
4.228LeuTrp: 4.228 ± 2.315
1.409LeuTyr: 1.409 ± 0.576
0.0LeuXaa: 0.0 ± 0.0
Met
0.705MetAla: 0.705 ± 0.593
0.705MetCys: 0.705 ± 0.7
1.409MetAsp: 1.409 ± 1.185
1.409MetGlu: 1.409 ± 0.576
2.819MetPhe: 2.819 ± 0.699
1.409MetGly: 1.409 ± 0.782
1.409MetHis: 1.409 ± 1.101
0.0MetIle: 0.0 ± 0.0
2.819MetLys: 2.819 ± 0.915
3.524MetLeu: 3.524 ± 2.697
0.705MetMet: 0.705 ± 0.593
0.705MetAsn: 0.705 ± 0.7
0.0MetPro: 0.0 ± 0.0
1.409MetGln: 1.409 ± 1.4
1.409MetArg: 1.409 ± 0.511
1.409MetSer: 1.409 ± 0.511
0.705MetThr: 0.705 ± 0.551
1.409MetVal: 1.409 ± 0.511
0.0MetTrp: 0.0 ± 0.0
0.705MetTyr: 0.705 ± 0.7
0.0MetXaa: 0.0 ± 0.0
Asn
1.409AsnAla: 1.409 ± 0.576
0.0AsnCys: 0.0 ± 0.0
1.409AsnAsp: 1.409 ± 0.576
1.409AsnGlu: 1.409 ± 1.101
0.705AsnPhe: 0.705 ± 0.7
1.409AsnGly: 1.409 ± 1.185
1.409AsnHis: 1.409 ± 0.511
0.705AsnIle: 0.705 ± 0.7
0.0AsnLys: 0.0 ± 0.0
2.114AsnLeu: 2.114 ± 0.881
1.409AsnMet: 1.409 ± 0.576
1.409AsnAsn: 1.409 ± 1.101
2.114AsnPro: 2.114 ± 0.96
1.409AsnGln: 1.409 ± 0.576
2.819AsnArg: 2.819 ± 1.378
2.114AsnSer: 2.114 ± 1.198
2.819AsnThr: 2.819 ± 0.336
0.705AsnVal: 0.705 ± 0.593
0.705AsnTrp: 0.705 ± 0.593
0.705AsnTyr: 0.705 ± 0.7
0.0AsnXaa: 0.0 ± 0.0
Pro
3.524ProAla: 3.524 ± 0.879
2.114ProCys: 2.114 ± 0.881
1.409ProAsp: 1.409 ± 0.576
4.228ProGlu: 4.228 ± 1.919
0.705ProPhe: 0.705 ± 0.593
3.524ProGly: 3.524 ± 0.655
0.0ProHis: 0.0 ± 0.0
4.228ProIle: 4.228 ± 0.486
2.114ProLys: 2.114 ± 1.652
4.228ProLeu: 4.228 ± 1.532
1.409ProMet: 1.409 ± 1.4
2.114ProAsn: 2.114 ± 0.96
1.409ProPro: 1.409 ± 1.101
2.114ProGln: 2.114 ± 0.96
1.409ProArg: 1.409 ± 1.101
9.866ProSer: 9.866 ± 1.184
3.524ProThr: 3.524 ± 1.905
4.933ProVal: 4.933 ± 1.978
0.705ProTrp: 0.705 ± 0.7
2.114ProTyr: 2.114 ± 0.243
0.0ProXaa: 0.0 ± 0.0
Gln
4.933GlnAla: 4.933 ± 1.929
0.705GlnCys: 0.705 ± 0.593
0.0GlnAsp: 0.0 ± 0.0
2.114GlnGlu: 2.114 ± 0.883
2.114GlnPhe: 2.114 ± 1.158
2.114GlnGly: 2.114 ± 0.881
3.524GlnHis: 3.524 ± 0.386
2.114GlnIle: 2.114 ± 1.198
0.0GlnLys: 0.0 ± 0.0
0.705GlnLeu: 0.705 ± 0.7
0.0GlnMet: 0.0 ± 0.0
0.0GlnAsn: 0.0 ± 0.0
0.705GlnPro: 0.705 ± 0.7
0.705GlnGln: 0.705 ± 0.593
2.819GlnArg: 2.819 ± 1.378
1.409GlnSer: 1.409 ± 1.101
1.409GlnThr: 1.409 ± 1.185
4.228GlnVal: 4.228 ± 1.314
0.0GlnTrp: 0.0 ± 0.0
0.0GlnTyr: 0.0 ± 0.0
0.0GlnXaa: 0.0 ± 0.0
Arg
3.524ArgAla: 3.524 ± 0.879
1.409ArgCys: 1.409 ± 0.782
2.819ArgAsp: 2.819 ± 1.511
3.524ArgGlu: 3.524 ± 0.655
2.819ArgPhe: 2.819 ± 1.378
2.819ArgGly: 2.819 ± 1.378
1.409ArgHis: 1.409 ± 1.101
3.524ArgIle: 3.524 ± 0.879
3.524ArgLys: 3.524 ± 2.106
11.276ArgLeu: 11.276 ± 1.856
1.409ArgMet: 1.409 ± 0.782
0.705ArgAsn: 0.705 ± 0.551
5.638ArgPro: 5.638 ± 1.113
0.705ArgGln: 0.705 ± 0.551
1.409ArgArg: 1.409 ± 1.101
3.524ArgSer: 3.524 ± 0.386
2.819ArgThr: 2.819 ± 0.336
5.638ArgVal: 5.638 ± 0.394
1.409ArgTrp: 1.409 ± 1.4
3.524ArgTyr: 3.524 ± 0.879
0.0ArgXaa: 0.0 ± 0.0
Ser
4.228SerAla: 4.228 ± 2.346
0.705SerCys: 0.705 ± 0.551
6.342SerAsp: 6.342 ± 2.203
4.228SerGlu: 4.228 ± 1.428
6.342SerPhe: 6.342 ± 2.205
7.752SerGly: 7.752 ± 2.888
0.705SerHis: 0.705 ± 0.7
2.819SerIle: 2.819 ± 0.336
2.114SerLys: 2.114 ± 1.778
7.047SerLeu: 7.047 ± 1.608
2.819SerMet: 2.819 ± 0.336
2.819SerAsn: 2.819 ± 2.203
6.342SerPro: 6.342 ± 1.376
4.228SerGln: 4.228 ± 1.762
8.457SerArg: 8.457 ± 0.219
9.161SerSer: 9.161 ± 4.0
7.047SerThr: 7.047 ± 0.892
7.752SerVal: 7.752 ± 3.293
0.705SerTrp: 0.705 ± 0.593
0.705SerTyr: 0.705 ± 0.593
0.0SerXaa: 0.0 ± 0.0
Thr
6.342ThrAla: 6.342 ± 2.203
0.705ThrCys: 0.705 ± 0.551
1.409ThrAsp: 1.409 ± 1.101
0.705ThrGlu: 0.705 ± 0.551
1.409ThrPhe: 1.409 ± 0.511
6.342ThrGly: 6.342 ± 2.879
0.705ThrHis: 0.705 ± 0.551
5.638ThrIle: 5.638 ± 1.258
0.705ThrLys: 0.705 ± 0.7
5.638ThrLeu: 5.638 ± 0.672
0.705ThrMet: 0.705 ± 0.551
3.524ThrAsn: 3.524 ± 0.386
3.524ThrPro: 3.524 ± 1.385
0.705ThrGln: 0.705 ± 0.551
1.409ThrArg: 1.409 ± 1.185
5.638ThrSer: 5.638 ± 1.664
3.524ThrThr: 3.524 ± 1.331
6.342ThrVal: 6.342 ± 2.203
1.409ThrTrp: 1.409 ± 0.511
2.114ThrTyr: 2.114 ± 0.243
0.0ThrXaa: 0.0 ± 0.0
Val
2.819ValAla: 2.819 ± 0.699
1.409ValCys: 1.409 ± 1.101
4.933ValAsp: 4.933 ± 1.526
3.524ValGlu: 3.524 ± 1.869
4.228ValPhe: 4.228 ± 1.393
6.342ValGly: 6.342 ± 2.399
1.409ValHis: 1.409 ± 0.782
1.409ValIle: 1.409 ± 0.511
4.228ValLys: 4.228 ± 2.31
4.228ValLeu: 4.228 ± 1.859
2.114ValMet: 2.114 ± 1.778
1.409ValAsn: 1.409 ± 0.782
6.342ValPro: 6.342 ± 3.279
0.705ValGln: 0.705 ± 0.7
5.638ValArg: 5.638 ± 1.345
7.047ValSer: 7.047 ± 3.629
4.228ValThr: 4.228 ± 1.766
7.752ValVal: 7.752 ± 2.9
1.409ValTrp: 1.409 ± 1.101
3.524ValTyr: 3.524 ± 1.019
0.0ValXaa: 0.0 ± 0.0
Trp
0.0TrpAla: 0.0 ± 0.0
0.0TrpCys: 0.0 ± 0.0
2.114TrpAsp: 2.114 ± 1.158
1.409TrpGlu: 1.409 ± 0.511
1.409TrpPhe: 1.409 ± 1.4
0.0TrpGly: 0.0 ± 0.0
0.705TrpHis: 0.705 ± 0.7
0.705TrpIle: 0.705 ± 0.593
2.114TrpLys: 2.114 ± 1.361
1.409TrpLeu: 1.409 ± 0.782
0.0TrpMet: 0.0 ± 0.0
0.705TrpAsn: 0.705 ± 0.7
0.705TrpPro: 0.705 ± 0.551
1.409TrpGln: 1.409 ± 0.576
0.705TrpArg: 0.705 ± 0.7
2.114TrpSer: 2.114 ± 0.881
0.0TrpThr: 0.0 ± 0.0
1.409TrpVal: 1.409 ± 0.782
0.0TrpTrp: 0.0 ± 0.0
1.409TrpTyr: 1.409 ± 0.576
0.0TrpXaa: 0.0 ± 0.0
Tyr
3.524TyrAla: 3.524 ± 1.019
1.409TyrCys: 1.409 ± 0.576
2.819TyrAsp: 2.819 ± 0.336
2.114TyrGlu: 2.114 ± 0.243
1.409TyrPhe: 1.409 ± 1.101
2.114TyrGly: 2.114 ± 1.198
1.409TyrHis: 1.409 ± 0.511
1.409TyrIle: 1.409 ± 0.782
2.819TyrLys: 2.819 ± 0.699
1.409TyrLeu: 1.409 ± 0.576
0.0TyrMet: 0.0 ± 0.0
0.0TyrAsn: 0.0 ± 0.0
2.114TyrPro: 2.114 ± 0.883
2.114TyrGln: 2.114 ± 0.883
3.524TyrArg: 3.524 ± 0.655
2.114TyrSer: 2.114 ± 0.881
1.409TyrThr: 1.409 ± 0.576
1.409TyrVal: 1.409 ± 0.782
1.409TyrTrp: 1.409 ± 0.511
0.705TyrTyr: 0.705 ± 0.7
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 3 proteins (1420 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski