Amino acid dipepetide frequency for Vannielia litorea

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.012AlaAla: 19.012 ± 0.183	1.254AlaCys: 1.254 ± 0.041	6.405AlaAsp: 6.405 ± 0.079	9.874AlaGlu: 9.874 ± 0.13	4.515AlaPhe: 4.515 ± 0.071	12.005AlaGly: 12.005 ± 0.129	2.345AlaHis: 2.345 ± 0.054	5.384AlaIle: 5.384 ± 0.063	3.38AlaLys: 3.38 ± 0.065	15.532AlaLeu: 15.532 ± 0.154	3.953AlaMet: 3.953 ± 0.064	2.555AlaAsn: 2.555 ± 0.046	6.903AlaPro: 6.903 ± 0.1	4.316AlaGln: 4.316 ± 0.056	10.059AlaArg: 10.059 ± 0.115	5.712AlaSer: 5.712 ± 0.077	6.317AlaThr: 6.317 ± 0.095	8.99AlaVal: 8.99 ± 0.093	1.727AlaTrp: 1.727 ± 0.043	2.468AlaTyr: 2.468 ± 0.049	0.0AlaXaa: 0.0 ± 0.0
Cys	1.106CysAla: 1.106 ± 0.03	0.095CysCys: 0.095 ± 0.009	0.551CysAsp: 0.551 ± 0.02	0.509CysGlu: 0.509 ± 0.019	0.356CysPhe: 0.356 ± 0.018	0.984CysGly: 0.984 ± 0.035	0.28CysHis: 0.28 ± 0.015	0.421CysIle: 0.421 ± 0.019	0.199CysLys: 0.199 ± 0.013	0.884CysLeu: 0.884 ± 0.028	0.177CysMet: 0.177 ± 0.012	0.227CysAsn: 0.227 ± 0.013	0.529CysPro: 0.529 ± 0.022	0.198CysGln: 0.198 ± 0.011	0.575CysArg: 0.575 ± 0.021	0.416CysSer: 0.416 ± 0.016	0.493CysThr: 0.493 ± 0.022	0.633CysVal: 0.633 ± 0.021	0.106CysTrp: 0.106 ± 0.008	0.21CysTyr: 0.21 ± 0.014	0.0CysXaa: 0.0 ± 0.0
Asp	6.739AspAla: 6.739 ± 0.083	0.485AspCys: 0.485 ± 0.021	2.992AspAsp: 2.992 ± 0.069	3.512AspGlu: 3.512 ± 0.063	2.13AspPhe: 2.13 ± 0.04	5.216AspGly: 5.216 ± 0.083	1.215AspHis: 1.215 ± 0.036	2.711AspIle: 2.711 ± 0.049	1.438AspLys: 1.438 ± 0.038	5.569AspLeu: 5.569 ± 0.073	1.501AspMet: 1.501 ± 0.032	1.118AspAsn: 1.118 ± 0.028	3.508AspPro: 3.508 ± 0.057	1.404AspGln: 1.404 ± 0.034	3.875AspArg: 3.875 ± 0.055	1.901AspSer: 1.901 ± 0.046	2.711AspThr: 2.711 ± 0.065	3.752AspVal: 3.752 ± 0.059	1.156AspTrp: 1.156 ± 0.034	1.453AspTyr: 1.453 ± 0.034	0.0AspXaa: 0.0 ± 0.0
Glu	10.354GluAla: 10.354 ± 0.139	0.338GluCys: 0.338 ± 0.017	3.204GluAsp: 3.204 ± 0.067	4.38GluGlu: 4.38 ± 0.094	1.825GluPhe: 1.825 ± 0.039	6.07GluGly: 6.07 ± 0.085	1.184GluHis: 1.184 ± 0.035	3.614GluIle: 3.614 ± 0.062	2.219GluLys: 2.219 ± 0.049	5.571GluLeu: 5.571 ± 0.083	1.967GluMet: 1.967 ± 0.039	1.633GluAsn: 1.633 ± 0.036	2.993GluPro: 2.993 ± 0.069	1.912GluGln: 1.912 ± 0.044	4.461GluArg: 4.461 ± 0.072	2.502GluSer: 2.502 ± 0.041	3.701GluThr: 3.701 ± 0.062	5.003GluVal: 5.003 ± 0.063	0.753GluTrp: 0.753 ± 0.022	0.974GluTyr: 0.974 ± 0.031	0.0GluXaa: 0.0 ± 0.0
Phe	4.549PheAla: 4.549 ± 0.069	0.443PheCys: 0.443 ± 0.02	2.583PheAsp: 2.583 ± 0.05	2.295PheGlu: 2.295 ± 0.042	1.411PhePhe: 1.411 ± 0.04	3.677PheGly: 3.677 ± 0.064	0.743PheHis: 0.743 ± 0.027	1.696PheIle: 1.696 ± 0.043	0.885PheLys: 0.885 ± 0.028	3.364PheLeu: 3.364 ± 0.056	0.821PheMet: 0.821 ± 0.028	0.997PheAsn: 0.997 ± 0.029	1.576PhePro: 1.576 ± 0.04	0.88PheGln: 0.88 ± 0.027	2.151PheArg: 2.151 ± 0.053	2.091PheSer: 2.091 ± 0.042	2.217PheThr: 2.217 ± 0.042	2.534PheVal: 2.534 ± 0.046	0.588PheTrp: 0.588 ± 0.025	0.917PheTyr: 0.917 ± 0.027	0.0PheXaa: 0.0 ± 0.0
Gly	11.037GlyAla: 11.037 ± 0.132	0.955GlyCys: 0.955 ± 0.03	4.459GlyAsp: 4.459 ± 0.08	5.641GlyGlu: 5.641 ± 0.079	3.828GlyPhe: 3.828 ± 0.05	8.305GlyGly: 8.305 ± 0.163	1.941GlyHis: 1.941 ± 0.047	4.28GlyIle: 4.28 ± 0.059	3.242GlyLys: 3.242 ± 0.055	9.898GlyLeu: 9.898 ± 0.098	2.644GlyMet: 2.644 ± 0.055	2.11GlyAsn: 2.11 ± 0.07	4.1GlyPro: 4.1 ± 0.064	3.065GlyGln: 3.065 ± 0.054	6.144GlyArg: 6.144 ± 0.078	4.28GlySer: 4.28 ± 0.095	5.047GlyThr: 5.047 ± 0.101	6.592GlyVal: 6.592 ± 0.074	1.68GlyTrp: 1.68 ± 0.04	2.332GlyTyr: 2.332 ± 0.044	0.0GlyXaa: 0.0 ± 0.0
His	2.36HisAla: 2.36 ± 0.051	0.221HisCys: 0.221 ± 0.012	1.177HisAsp: 1.177 ± 0.034	1.093HisGlu: 1.093 ± 0.032	0.812HisPhe: 0.812 ± 0.024	1.976HisGly: 1.976 ± 0.049	0.572HisHis: 0.572 ± 0.023	0.914HisIle: 0.914 ± 0.026	0.482HisLys: 0.482 ± 0.021	2.014HisLeu: 2.014 ± 0.046	0.543HisMet: 0.543 ± 0.022	0.42HisAsn: 0.42 ± 0.02	1.424HisPro: 1.424 ± 0.037	0.526HisGln: 0.526 ± 0.019	1.41HisArg: 1.41 ± 0.03	0.852HisSer: 0.852 ± 0.027	0.778HisThr: 0.778 ± 0.026	1.511HisVal: 1.511 ± 0.038	0.362HisTrp: 0.362 ± 0.02	0.582HisTyr: 0.582 ± 0.023	0.0HisXaa: 0.0 ± 0.0
Ile	6.443IleAla: 6.443 ± 0.077	0.577IleCys: 0.577 ± 0.021	3.14IleAsp: 3.14 ± 0.056	3.329IleGlu: 3.329 ± 0.056	1.681IlePhe: 1.681 ± 0.045	4.696IleGly: 4.696 ± 0.07	0.919IleHis: 0.919 ± 0.029	1.921IleIle: 1.921 ± 0.043	1.136IleLys: 1.136 ± 0.032	4.213IleLeu: 4.213 ± 0.064	0.949IleMet: 0.949 ± 0.026	1.18IleAsn: 1.18 ± 0.035	2.223IlePro: 2.223 ± 0.044	1.002IleGln: 1.002 ± 0.03	3.006IleArg: 3.006 ± 0.057	2.63IleSer: 2.63 ± 0.046	2.877IleThr: 2.877 ± 0.055	3.474IleVal: 3.474 ± 0.059	0.67IleTrp: 0.67 ± 0.025	1.081IleTyr: 1.081 ± 0.035	0.0IleXaa: 0.0 ± 0.0
Lys	4.106LysAla: 4.106 ± 0.075	0.158LysCys: 0.158 ± 0.012	1.487LysAsp: 1.487 ± 0.043	1.47LysGlu: 1.47 ± 0.044	0.848LysPhe: 0.848 ± 0.025	2.735LysGly: 2.735 ± 0.051	0.558LysHis: 0.558 ± 0.022	1.409LysIle: 1.409 ± 0.041	1.119LysLys: 1.119 ± 0.04	2.884LysLeu: 2.884 ± 0.051	0.757LysMet: 0.757 ± 0.027	0.695LysAsn: 0.695 ± 0.027	1.813LysPro: 1.813 ± 0.04	0.826LysGln: 0.826 ± 0.032	1.99LysArg: 1.99 ± 0.048	1.6LysSer: 1.6 ± 0.038	1.614LysThr: 1.614 ± 0.041	2.311LysVal: 2.311 ± 0.051	0.404LysTrp: 0.404 ± 0.02	0.581LysTyr: 0.581 ± 0.022	0.0LysXaa: 0.0 ± 0.0
Leu	14.926LeuAla: 14.926 ± 0.164	0.986LeuCys: 0.986 ± 0.033	5.67LeuAsp: 5.67 ± 0.069	5.752LeuGlu: 5.752 ± 0.077	3.528LeuPhe: 3.528 ± 0.062	8.919LeuGly: 8.919 ± 0.094	1.902LeuHis: 1.902 ± 0.045	4.635LeuIle: 4.635 ± 0.068	3.271LeuLys: 3.271 ± 0.064	9.396LeuLeu: 9.396 ± 0.122	2.716LeuMet: 2.716 ± 0.052	2.373LeuAsn: 2.373 ± 0.049	5.837LeuPro: 5.837 ± 0.087	2.382LeuGln: 2.382 ± 0.044	6.876LeuArg: 6.876 ± 0.085	6.058LeuSer: 6.058 ± 0.071	6.015LeuThr: 6.015 ± 0.075	7.307LeuVal: 7.307 ± 0.076	1.387LeuTrp: 1.387 ± 0.034	1.982LeuTyr: 1.982 ± 0.042	0.0LeuXaa: 0.0 ± 0.0
Met	3.609MetAla: 3.609 ± 0.056	0.182MetCys: 0.182 ± 0.012	1.306MetAsp: 1.306 ± 0.035	1.513MetGlu: 1.513 ± 0.029	0.757MetPhe: 0.757 ± 0.027	2.378MetGly: 2.378 ± 0.051	0.463MetHis: 0.463 ± 0.018	1.396MetIle: 1.396 ± 0.036	1.081MetLys: 1.081 ± 0.028	2.551MetLeu: 2.551 ± 0.047	0.728MetMet: 0.728 ± 0.025	0.815MetAsn: 0.815 ± 0.024	1.535MetPro: 1.535 ± 0.039	0.873MetGln: 0.873 ± 0.024	1.869MetArg: 1.869 ± 0.042	1.667MetSer: 1.667 ± 0.039	1.897MetThr: 1.897 ± 0.039	1.914MetVal: 1.914 ± 0.042	0.249MetTrp: 0.249 ± 0.015	0.309MetTyr: 0.309 ± 0.015	0.0MetXaa: 0.0 ± 0.0
Asn	3.006AsnAla: 3.006 ± 0.055	0.245AsnCys: 0.245 ± 0.014	1.299AsnAsp: 1.299 ± 0.045	1.11AsnGlu: 1.11 ± 0.031	0.92AsnPhe: 0.92 ± 0.032	2.226AsnGly: 2.226 ± 0.054	0.453AsnHis: 0.453 ± 0.021	1.231AsnIle: 1.231 ± 0.033	0.552AsnLys: 0.552 ± 0.026	2.374AsnLeu: 2.374 ± 0.046	0.638AsnMet: 0.638 ± 0.025	0.632AsnAsn: 0.632 ± 0.029	1.801AsnPro: 1.801 ± 0.036	0.611AsnGln: 0.611 ± 0.025	1.606AsnArg: 1.606 ± 0.04	0.994AsnSer: 0.994 ± 0.031	1.218AsnThr: 1.218 ± 0.04	1.639AsnVal: 1.639 ± 0.039	0.393AsnTrp: 0.393 ± 0.019	0.605AsnTyr: 0.605 ± 0.023	0.0AsnXaa: 0.0 ± 0.0
Pro	6.508ProAla: 6.508 ± 0.103	0.378ProCys: 0.378 ± 0.017	3.593ProAsp: 3.593 ± 0.069	5.2ProGlu: 5.2 ± 0.079	1.948ProPhe: 1.948 ± 0.044	5.291ProGly: 5.291 ± 0.074	1.083ProHis: 1.083 ± 0.032	2.075ProIle: 2.075 ± 0.043	1.471ProLys: 1.471 ± 0.04	4.952ProLeu: 4.952 ± 0.07	1.389ProMet: 1.389 ± 0.032	1.152ProAsn: 1.152 ± 0.033	2.534ProPro: 2.534 ± 0.067	1.624ProGln: 1.624 ± 0.04	3.224ProArg: 3.224 ± 0.05	2.471ProSer: 2.471 ± 0.044	2.325ProThr: 2.325 ± 0.043	4.396ProVal: 4.396 ± 0.07	0.747ProTrp: 0.747 ± 0.023	1.104ProTyr: 1.104 ± 0.03	0.0ProXaa: 0.0 ± 0.0
Gln	3.889GlnAla: 3.889 ± 0.056	0.2GlnCys: 0.2 ± 0.012	1.369GlnAsp: 1.369 ± 0.033	1.553GlnGlu: 1.553 ± 0.037	0.934GlnPhe: 0.934 ± 0.028	2.625GlnGly: 2.625 ± 0.048	0.547GlnHis: 0.547 ± 0.023	1.652GlnIle: 1.652 ± 0.035	0.981GlnLys: 0.981 ± 0.033	2.631GlnLeu: 2.631 ± 0.044	0.933GlnMet: 0.933 ± 0.026	0.77GlnAsn: 0.77 ± 0.028	1.578GlnPro: 1.578 ± 0.039	0.99GlnGln: 0.99 ± 0.034	1.991GlnArg: 1.991 ± 0.041	1.541GlnSer: 1.541 ± 0.036	1.492GlnThr: 1.492 ± 0.033	2.338GlnVal: 2.338 ± 0.045	0.372GlnTrp: 0.372 ± 0.016	0.515GlnTyr: 0.515 ± 0.021	0.0GlnXaa: 0.0 ± 0.0
Arg	8.894ArgAla: 8.894 ± 0.115	0.497ArgCys: 0.497 ± 0.02	3.71ArgAsp: 3.71 ± 0.059	4.318ArgGlu: 4.318 ± 0.063	2.691ArgPhe: 2.691 ± 0.051	4.972ArgGly: 4.972 ± 0.064	1.522ArgHis: 1.522 ± 0.04	3.623ArgIle: 3.623 ± 0.063	2.155ArgLys: 2.155 ± 0.044	7.618ArgLeu: 7.618 ± 0.093	2.04ArgMet: 2.04 ± 0.04	1.644ArgAsn: 1.644 ± 0.04	3.471ArgPro: 3.471 ± 0.057	2.19ArgGln: 2.19 ± 0.045	5.23ArgArg: 5.23 ± 0.072	3.238ArgSer: 3.238 ± 0.054	3.022ArgThr: 3.022 ± 0.048	4.885ArgVal: 4.885 ± 0.07	0.992ArgTrp: 0.992 ± 0.033	1.503ArgTyr: 1.503 ± 0.039	0.0ArgXaa: 0.0 ± 0.0
Ser	5.936SerAla: 5.936 ± 0.088	0.403SerCys: 0.403 ± 0.019	2.733SerAsp: 2.733 ± 0.048	2.926SerGlu: 2.926 ± 0.057	2.148SerPhe: 2.148 ± 0.041	5.278SerGly: 5.278 ± 0.086	1.101SerHis: 1.101 ± 0.034	2.202SerIle: 2.202 ± 0.048	1.304SerLys: 1.304 ± 0.035	4.91SerLeu: 4.91 ± 0.063	1.246SerMet: 1.246 ± 0.036	1.148SerAsn: 1.148 ± 0.032	2.543SerPro: 2.543 ± 0.044	1.454SerGln: 1.454 ± 0.034	3.271SerArg: 3.271 ± 0.058	2.4SerSer: 2.4 ± 0.055	2.434SerThr: 2.434 ± 0.055	3.449SerVal: 3.449 ± 0.058	0.708SerTrp: 0.708 ± 0.027	1.245SerTyr: 1.245 ± 0.031	0.0SerXaa: 0.0 ± 0.0
Thr	6.566ThrAla: 6.566 ± 0.098	0.53ThrCys: 0.53 ± 0.022	2.786ThrAsp: 2.786 ± 0.054	3.18ThrGlu: 3.18 ± 0.048	1.907ThrPhe: 1.907 ± 0.047	5.626ThrGly: 5.626 ± 0.102	1.078ThrHis: 1.078 ± 0.028	2.403ThrIle: 2.403 ± 0.053	1.189ThrLys: 1.189 ± 0.034	5.983ThrLeu: 5.983 ± 0.093	1.138ThrMet: 1.138 ± 0.034	1.17ThrAsn: 1.17 ± 0.044	3.609ThrPro: 3.609 ± 0.056	1.343ThrGln: 1.343 ± 0.035	3.774ThrArg: 3.774 ± 0.058	2.477ThrSer: 2.477 ± 0.067	2.779ThrThr: 2.779 ± 0.068	4.18ThrVal: 4.18 ± 0.081	0.747ThrTrp: 0.747 ± 0.024	1.213ThrTyr: 1.213 ± 0.031	0.0ThrXaa: 0.0 ± 0.0
Val	9.539ValAla: 9.539 ± 0.108	0.629ValCys: 0.629 ± 0.023	3.752ValAsp: 3.752 ± 0.057	4.961ValGlu: 4.961 ± 0.07	2.757ValPhe: 2.757 ± 0.054	5.421ValGly: 5.421 ± 0.07	1.271ValHis: 1.271 ± 0.031	3.986ValIle: 3.986 ± 0.057	2.217ValLys: 2.217 ± 0.052	7.658ValLeu: 7.658 ± 0.095	2.099ValMet: 2.099 ± 0.042	1.984ValAsn: 1.984 ± 0.053	3.686ValPro: 3.686 ± 0.06	2.04ValGln: 2.04 ± 0.045	4.049ValArg: 4.049 ± 0.061	4.127ValSer: 4.127 ± 0.06	4.916ValThr: 4.916 ± 0.091	5.926ValVal: 5.926 ± 0.073	0.881ValTrp: 0.881 ± 0.027	1.386ValTyr: 1.386 ± 0.034	0.0ValXaa: 0.0 ± 0.0
Trp	1.541TrpAla: 1.541 ± 0.042	0.143TrpCys: 0.143 ± 0.011	0.725TrpAsp: 0.725 ± 0.023	0.801TrpGlu: 0.801 ± 0.026	0.574TrpPhe: 0.574 ± 0.022	1.11TrpGly: 1.11 ± 0.027	0.348TrpHis: 0.348 ± 0.018	0.676TrpIle: 0.676 ± 0.024	0.485TrpLys: 0.485 ± 0.02	1.763TrpLeu: 1.763 ± 0.04	0.397TrpMet: 0.397 ± 0.018	0.398TrpAsn: 0.398 ± 0.017	0.732TrpPro: 0.732 ± 0.025	0.623TrpGln: 0.623 ± 0.022	1.156TrpArg: 1.156 ± 0.035	0.799TrpSer: 0.799 ± 0.026	0.699TrpThr: 0.699 ± 0.024	1.021TrpVal: 1.021 ± 0.029	0.245TrpTrp: 0.245 ± 0.015	0.281TrpTyr: 0.281 ± 0.016	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.584TyrAla: 2.584 ± 0.052	0.228TyrCys: 0.228 ± 0.016	1.446TyrAsp: 1.446 ± 0.034	1.24TyrGlu: 1.24 ± 0.035	0.848TyrPhe: 0.848 ± 0.029	2.071TyrGly: 2.071 ± 0.037	0.505TyrHis: 0.505 ± 0.021	0.918TyrIle: 0.918 ± 0.03	0.558TyrLys: 0.558 ± 0.023	2.151TyrLeu: 2.151 ± 0.042	0.456TyrMet: 0.456 ± 0.019	0.533TyrAsn: 0.533 ± 0.023	1.074TyrPro: 1.074 ± 0.027	0.643TyrGln: 0.643 ± 0.022	1.497TyrArg: 1.497 ± 0.037	1.083TyrSer: 1.083 ± 0.028	1.126TyrThr: 1.126 ± 0.033	1.432TyrVal: 1.432 ± 0.036	0.348TyrTrp: 0.348 ± 0.014	0.567TyrTyr: 0.567 ± 0.025	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4018 proteins (1242426 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

---