Amino acid dipepetide frequency for Cochliobolus sativus (strain ND90Pr / ATCC 201652) (Common root rot and spot blotch fungus) (Bipolaris sorokiniana)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
8.964AlaAla: 8.964 ± 0.065
1.152AlaCys: 1.152 ± 0.016
4.18AlaAsp: 4.18 ± 0.031
5.082AlaGlu: 5.082 ± 0.043
3.172AlaPhe: 3.172 ± 0.026
5.572AlaGly: 5.572 ± 0.043
1.917AlaHis: 1.917 ± 0.02
4.32AlaIle: 4.32 ± 0.033
4.446AlaLys: 4.446 ± 0.04
7.698AlaLeu: 7.698 ± 0.043
2.02AlaMet: 2.02 ± 0.02
3.156AlaAsn: 3.156 ± 0.025
5.14AlaPro: 5.14 ± 0.042
3.678AlaGln: 3.678 ± 0.03
4.903AlaArg: 4.903 ± 0.035
7.402AlaSer: 7.402 ± 0.052
5.427AlaThr: 5.427 ± 0.032
5.243AlaVal: 5.243 ± 0.038
1.169AlaTrp: 1.169 ± 0.016
2.311AlaTyr: 2.311 ± 0.022
0.0AlaXaa: 0.0 ± 0.0
Cys
1.006CysAla: 1.006 ± 0.014
0.284CysCys: 0.284 ± 0.009
0.671CysAsp: 0.671 ± 0.012
0.614CysGlu: 0.614 ± 0.011
0.561CysPhe: 0.561 ± 0.011
0.987CysGly: 0.987 ± 0.017
0.331CysHis: 0.331 ± 0.008
0.78CysIle: 0.78 ± 0.013
0.579CysLys: 0.579 ± 0.01
1.231CysLeu: 1.231 ± 0.02
0.307CysMet: 0.307 ± 0.008
0.49CysAsn: 0.49 ± 0.01
0.677CysPro: 0.677 ± 0.013
0.467CysGln: 0.467 ± 0.011
0.752CysArg: 0.752 ± 0.013
0.962CysSer: 0.962 ± 0.015
0.788CysThr: 0.788 ± 0.014
0.848CysVal: 0.848 ± 0.014
0.216CysTrp: 0.216 ± 0.007
0.375CysTyr: 0.375 ± 0.008
0.0CysXaa: 0.0 ± 0.0
Asp
4.928AspAla: 4.928 ± 0.031
0.641AspCys: 0.641 ± 0.011
4.137AspAsp: 4.137 ± 0.041
4.373AspGlu: 4.373 ± 0.036
2.171AspPhe: 2.171 ± 0.02
3.746AspGly: 3.746 ± 0.031
1.192AspHis: 1.192 ± 0.018
3.016AspIle: 3.016 ± 0.028
2.526AspLys: 2.526 ± 0.026
4.704AspLeu: 4.704 ± 0.033
1.399AspMet: 1.399 ± 0.015
1.878AspAsn: 1.878 ± 0.019
3.171AspPro: 3.171 ± 0.03
1.824AspGln: 1.824 ± 0.018
2.881AspArg: 2.881 ± 0.027
3.928AspSer: 3.928 ± 0.035
3.04AspThr: 3.04 ± 0.024
3.651AspVal: 3.651 ± 0.027
0.888AspTrp: 0.888 ± 0.014
1.599AspTyr: 1.599 ± 0.021
0.0AspXaa: 0.0 ± 0.0
Glu
5.375GluAla: 5.375 ± 0.043
0.641GluCys: 0.641 ± 0.01
4.103GluAsp: 4.103 ± 0.038
5.48GluGlu: 5.48 ± 0.051
1.883GluPhe: 1.883 ± 0.02
3.779GluGly: 3.779 ± 0.03
1.479GluHis: 1.479 ± 0.016
2.937GluIle: 2.937 ± 0.027
3.933GluLys: 3.933 ± 0.032
4.976GluLeu: 4.976 ± 0.034
1.445GluMet: 1.445 ± 0.017
2.225GluAsn: 2.225 ± 0.021
2.745GluPro: 2.745 ± 0.037
2.641GluGln: 2.641 ± 0.024
3.93GluArg: 3.93 ± 0.035
3.995GluSer: 3.995 ± 0.037
3.319GluThr: 3.319 ± 0.026
3.47GluVal: 3.47 ± 0.028
0.922GluTrp: 0.922 ± 0.014
1.712GluTyr: 1.712 ± 0.017
0.0GluXaa: 0.0 ± 0.0
Phe
3.134PheAla: 3.134 ± 0.026
0.567PheCys: 0.567 ± 0.012
2.249PheAsp: 2.249 ± 0.02
2.103PheGlu: 2.103 ± 0.022
1.662PhePhe: 1.662 ± 0.02
2.799PheGly: 2.799 ± 0.028
0.856PheHis: 0.856 ± 0.013
1.763PheIle: 1.763 ± 0.02
1.581PheLys: 1.581 ± 0.018
3.356PheLeu: 3.356 ± 0.027
0.767PheMet: 0.767 ± 0.012
1.467PheAsn: 1.467 ± 0.017
1.926PhePro: 1.926 ± 0.022
1.366PheGln: 1.366 ± 0.016
1.882PheArg: 1.882 ± 0.019
3.001PheSer: 3.001 ± 0.028
2.228PheThr: 2.228 ± 0.021
2.349PheVal: 2.349 ± 0.022
0.653PheTrp: 0.653 ± 0.012
1.074PheTyr: 1.074 ± 0.015
0.0PheXaa: 0.0 ± 0.0
Gly
5.293GlyAla: 5.293 ± 0.039
0.922GlyCys: 0.922 ± 0.014
3.443GlyAsp: 3.443 ± 0.028
3.619GlyGlu: 3.619 ± 0.035
2.74GlyPhe: 2.74 ± 0.027
5.682GlyGly: 5.682 ± 0.066
1.676GlyHis: 1.676 ± 0.019
3.478GlyIle: 3.478 ± 0.029
3.63GlyLys: 3.63 ± 0.033
5.717GlyLeu: 5.717 ± 0.037
1.669GlyMet: 1.669 ± 0.022
2.54GlyAsn: 2.54 ± 0.029
3.157GlyPro: 3.157 ± 0.029
2.533GlyGln: 2.533 ± 0.027
3.927GlyArg: 3.927 ± 0.034
5.337GlySer: 5.337 ± 0.036
3.904GlyThr: 3.904 ± 0.033
4.242GlyVal: 4.242 ± 0.035
1.172GlyTrp: 1.172 ± 0.017
2.134GlyTyr: 2.134 ± 0.022
0.0GlyXaa: 0.0 ± 0.0
His
2.016HisAla: 2.016 ± 0.022
0.366HisCys: 0.366 ± 0.008
1.344HisAsp: 1.344 ± 0.017
1.374HisGlu: 1.374 ± 0.018
0.923HisPhe: 0.923 ± 0.014
1.692HisGly: 1.692 ± 0.018
0.905HisHis: 0.905 ± 0.018
1.26HisIle: 1.26 ± 0.014
1.006HisLys: 1.006 ± 0.013
2.232HisLeu: 2.232 ± 0.023
0.539HisMet: 0.539 ± 0.01
0.915HisAsn: 0.915 ± 0.013
1.678HisPro: 1.678 ± 0.021
1.028HisGln: 1.028 ± 0.016
1.496HisArg: 1.496 ± 0.018
1.934HisSer: 1.934 ± 0.024
1.454HisThr: 1.454 ± 0.017
1.498HisVal: 1.498 ± 0.018
0.347HisTrp: 0.347 ± 0.008
0.73HisTyr: 0.73 ± 0.012
0.0HisXaa: 0.0 ± 0.0
Ile
4.402IleAla: 4.402 ± 0.031
0.762IleCys: 0.762 ± 0.012
2.856IleAsp: 2.856 ± 0.026
2.914IleGlu: 2.914 ± 0.025
1.969IlePhe: 1.969 ± 0.023
3.177IleGly: 3.177 ± 0.029
1.227IleHis: 1.227 ± 0.015
2.521IleIle: 2.521 ± 0.027
2.34IleLys: 2.34 ± 0.021
4.384IleLeu: 4.384 ± 0.033
1.053IleMet: 1.053 ± 0.015
1.839IleAsn: 1.839 ± 0.02
3.084IlePro: 3.084 ± 0.026
1.935IleGln: 1.935 ± 0.022
2.767IleArg: 2.767 ± 0.022
3.775IleSer: 3.775 ± 0.028
2.976IleThr: 2.976 ± 0.025
3.196IleVal: 3.196 ± 0.027
0.743IleTrp: 0.743 ± 0.014
1.449IleTyr: 1.449 ± 0.017
0.0IleXaa: 0.0 ± 0.0
Lys
4.447LysAla: 4.447 ± 0.037
0.547LysCys: 0.547 ± 0.01
2.983LysAsp: 2.983 ± 0.025
3.69LysGlu: 3.69 ± 0.033
1.493LysPhe: 1.493 ± 0.017
3.186LysGly: 3.186 ± 0.029
1.228LysHis: 1.228 ± 0.016
2.388LysIle: 2.388 ± 0.021
3.762LysLys: 3.762 ± 0.045
4.153LysLeu: 4.153 ± 0.028
1.097LysMet: 1.097 ± 0.016
1.946LysAsn: 1.946 ± 0.02
2.92LysPro: 2.92 ± 0.028
2.097LysGln: 2.097 ± 0.022
3.577LysArg: 3.577 ± 0.03
3.635LysSer: 3.635 ± 0.031
3.015LysThr: 3.015 ± 0.023
2.882LysVal: 2.882 ± 0.027
0.72LysTrp: 0.72 ± 0.012
1.469LysTyr: 1.469 ± 0.018
0.0LysXaa: 0.0 ± 0.0
Leu
7.691LeuAla: 7.691 ± 0.05
1.243LeuCys: 1.243 ± 0.017
4.964LeuAsp: 4.964 ± 0.03
5.305LeuGlu: 5.305 ± 0.042
3.236LeuPhe: 3.236 ± 0.029
5.599LeuGly: 5.599 ± 0.039
2.275LeuHis: 2.275 ± 0.022
3.882LeuIle: 3.882 ± 0.031
4.258LeuLys: 4.258 ± 0.029
8.072LeuLeu: 8.072 ± 0.054
1.753LeuMet: 1.753 ± 0.019
3.142LeuAsn: 3.142 ± 0.026
5.438LeuPro: 5.438 ± 0.037
3.825LeuGln: 3.825 ± 0.034
5.48LeuArg: 5.48 ± 0.034
7.04LeuSer: 7.04 ± 0.045
4.708LeuThr: 4.708 ± 0.029
5.276LeuVal: 5.276 ± 0.038
1.176LeuTrp: 1.176 ± 0.017
2.377LeuTyr: 2.377 ± 0.022
0.0LeuXaa: 0.0 ± 0.0
Met
2.239MetAla: 2.239 ± 0.019
0.276MetCys: 0.276 ± 0.008
1.277MetAsp: 1.277 ± 0.016
1.257MetGlu: 1.257 ± 0.014
0.783MetPhe: 0.783 ± 0.013
1.508MetGly: 1.508 ± 0.02
0.561MetHis: 0.561 ± 0.011
0.976MetIle: 0.976 ± 0.013
1.053MetLys: 1.053 ± 0.015
1.937MetLeu: 1.937 ± 0.019
0.594MetMet: 0.594 ± 0.011
0.846MetAsn: 0.846 ± 0.013
1.372MetPro: 1.372 ± 0.016
0.988MetGln: 0.988 ± 0.015
1.341MetArg: 1.341 ± 0.016
1.926MetSer: 1.926 ± 0.022
1.303MetThr: 1.303 ± 0.019
1.307MetVal: 1.307 ± 0.017
0.278MetTrp: 0.278 ± 0.007
0.609MetTyr: 0.609 ± 0.011
0.0MetXaa: 0.0 ± 0.0
Asn
3.394AsnAla: 3.394 ± 0.029
0.452AsnCys: 0.452 ± 0.01
2.007AsnAsp: 2.007 ± 0.022
2.072AsnGlu: 2.072 ± 0.019
1.397AsnPhe: 1.397 ± 0.019
3.034AsnGly: 3.034 ± 0.03
0.86AsnHis: 0.86 ± 0.011
2.104AsnIle: 2.104 ± 0.021
1.753AsnLys: 1.753 ± 0.019
3.236AsnLeu: 3.236 ± 0.03
0.914AsnMet: 0.914 ± 0.015
1.661AsnAsn: 1.661 ± 0.024
2.436AsnPro: 2.436 ± 0.021
1.419AsnGln: 1.419 ± 0.018
1.908AsnArg: 1.908 ± 0.021
2.8AsnSer: 2.8 ± 0.023
2.369AsnThr: 2.369 ± 0.021
2.385AsnVal: 2.385 ± 0.022
0.575AsnTrp: 0.575 ± 0.01
1.1AsnTyr: 1.1 ± 0.016
0.0AsnXaa: 0.0 ± 0.0
Pro
5.357ProAla: 5.357 ± 0.048
0.559ProCys: 0.559 ± 0.011
3.055ProAsp: 3.055 ± 0.023
3.667ProGlu: 3.667 ± 0.034
2.048ProPhe: 2.048 ± 0.023
3.686ProGly: 3.686 ± 0.031
1.473ProHis: 1.473 ± 0.016
2.657ProIle: 2.657 ± 0.021
2.886ProLys: 2.886 ± 0.03
4.699ProLeu: 4.699 ± 0.026
1.143ProMet: 1.143 ± 0.018
2.365ProAsn: 2.365 ± 0.022
5.308ProPro: 5.308 ± 0.087
2.671ProGln: 2.671 ± 0.031
3.332ProArg: 3.332 ± 0.034
5.958ProSer: 5.958 ± 0.047
4.263ProThr: 4.263 ± 0.035
3.503ProVal: 3.503 ± 0.028
0.722ProTrp: 0.722 ± 0.012
1.61ProTyr: 1.61 ± 0.019
0.0ProXaa: 0.0 ± 0.0
Gln
3.537GlnAla: 3.537 ± 0.031
0.496GlnCys: 0.496 ± 0.009
2.203GlnAsp: 2.203 ± 0.02
2.451GlnGlu: 2.451 ± 0.023
1.276GlnPhe: 1.276 ± 0.015
2.496GlnGly: 2.496 ± 0.027
1.227GlnHis: 1.227 ± 0.017
1.931GlnIle: 1.931 ± 0.02
2.121GlnLys: 2.121 ± 0.022
3.46GlnLeu: 3.46 ± 0.03
0.907GlnMet: 0.907 ± 0.016
1.653GlnAsn: 1.653 ± 0.02
2.692GlnPro: 2.692 ± 0.035
2.867GlnGln: 2.867 ± 0.06
2.761GlnArg: 2.761 ± 0.029
3.236GlnSer: 3.236 ± 0.03
2.397GlnThr: 2.397 ± 0.024
2.195GlnVal: 2.195 ± 0.02
0.599GlnTrp: 0.599 ± 0.011
1.259GlnTyr: 1.259 ± 0.017
0.0GlnXaa: 0.0 ± 0.0
Arg
4.632ArgAla: 4.632 ± 0.032
0.753ArgCys: 0.753 ± 0.014
3.22ArgAsp: 3.22 ± 0.028
3.697ArgGlu: 3.697 ± 0.031
2.089ArgPhe: 2.089 ± 0.019
3.572ArgGly: 3.572 ± 0.034
1.531ArgHis: 1.531 ± 0.019
2.994ArgIle: 2.994 ± 0.023
3.621ArgLys: 3.621 ± 0.03
5.223ArgLeu: 5.223 ± 0.033
1.367ArgMet: 1.367 ± 0.018
2.366ArgAsn: 2.366 ± 0.02
3.446ArgPro: 3.446 ± 0.031
2.638ArgGln: 2.638 ± 0.025
4.792ArgArg: 4.792 ± 0.049
4.657ArgSer: 4.657 ± 0.046
3.337ArgThr: 3.337 ± 0.026
3.218ArgVal: 3.218 ± 0.025
0.908ArgTrp: 0.908 ± 0.014
1.666ArgTyr: 1.666 ± 0.017
0.0ArgXaa: 0.0 ± 0.0
Ser
6.673SerAla: 6.673 ± 0.042
0.925SerCys: 0.925 ± 0.015
4.051SerAsp: 4.051 ± 0.034
4.004SerGlu: 4.004 ± 0.031
2.976SerPhe: 2.976 ± 0.026
5.271SerGly: 5.271 ± 0.035
2.054SerHis: 2.054 ± 0.023
4.04SerIle: 4.04 ± 0.032
3.879SerLys: 3.879 ± 0.031
6.921SerLeu: 6.921 ± 0.044
1.783SerMet: 1.783 ± 0.021
3.097SerAsn: 3.097 ± 0.025
5.49SerPro: 5.49 ± 0.057
3.267SerGln: 3.267 ± 0.027
4.837SerArg: 4.837 ± 0.045
8.351SerSer: 8.351 ± 0.074
5.629SerThr: 5.629 ± 0.043
4.463SerVal: 4.463 ± 0.033
1.093SerTrp: 1.093 ± 0.015
2.139SerTyr: 2.139 ± 0.023
0.0SerXaa: 0.0 ± 0.0
Thr
5.253ThrAla: 5.253 ± 0.037
0.832ThrCys: 0.832 ± 0.012
2.79ThrAsp: 2.79 ± 0.023
3.055ThrGlu: 3.055 ± 0.027
2.274ThrPhe: 2.274 ± 0.021
4.036ThrGly: 4.036 ± 0.03
1.411ThrHis: 1.411 ± 0.018
3.184ThrIle: 3.184 ± 0.025
2.841ThrLys: 2.841 ± 0.028
5.4ThrLeu: 5.4 ± 0.041
1.25ThrMet: 1.25 ± 0.017
2.262ThrAsn: 2.262 ± 0.021
4.606ThrPro: 4.606 ± 0.041
2.263ThrGln: 2.263 ± 0.023
3.204ThrArg: 3.204 ± 0.03
5.383ThrSer: 5.383 ± 0.04
4.436ThrThr: 4.436 ± 0.042
3.673ThrVal: 3.673 ± 0.027
0.869ThrTrp: 0.869 ± 0.012
1.697ThrTyr: 1.697 ± 0.018
0.0ThrXaa: 0.0 ± 0.0
Val
5.218ValAla: 5.218 ± 0.035
0.859ValCys: 0.859 ± 0.014
3.559ValAsp: 3.559 ± 0.027
3.821ValGlu: 3.821 ± 0.027
2.381ValPhe: 2.381 ± 0.023
3.971ValGly: 3.971 ± 0.031
1.417ValHis: 1.417 ± 0.014
2.856ValIle: 2.856 ± 0.029
2.982ValLys: 2.982 ± 0.029
5.429ValLeu: 5.429 ± 0.04
1.35ValMet: 1.35 ± 0.017
2.191ValAsn: 2.191 ± 0.021
3.514ValPro: 3.514 ± 0.027
2.486ValGln: 2.486 ± 0.024
3.385ValArg: 3.385 ± 0.025
4.456ValSer: 4.456 ± 0.033
3.456ValThr: 3.456 ± 0.026
4.224ValVal: 4.224 ± 0.034
0.885ValTrp: 0.885 ± 0.014
1.747ValTyr: 1.747 ± 0.02
0.0ValXaa: 0.0 ± 0.0
Trp
1.134TrpAla: 1.134 ± 0.014
0.212TrpCys: 0.212 ± 0.006
0.92TrpAsp: 0.92 ± 0.016
0.834TrpGlu: 0.834 ± 0.013
0.541TrpPhe: 0.541 ± 0.01
0.942TrpGly: 0.942 ± 0.014
0.363TrpHis: 0.363 ± 0.008
0.802TrpIle: 0.802 ± 0.013
0.814TrpLys: 0.814 ± 0.012
1.312TrpLeu: 1.312 ± 0.018
0.375TrpMet: 0.375 ± 0.009
0.65TrpAsn: 0.65 ± 0.011
0.6TrpPro: 0.6 ± 0.01
0.61TrpGln: 0.61 ± 0.01
0.931TrpArg: 0.931 ± 0.013
1.065TrpSer: 1.065 ± 0.014
0.922TrpThr: 0.922 ± 0.015
0.906TrpVal: 0.906 ± 0.016
0.281TrpTrp: 0.281 ± 0.009
0.458TrpTyr: 0.458 ± 0.01
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.262TyrAla: 2.262 ± 0.023
0.437TyrCys: 0.437 ± 0.009
1.682TyrAsp: 1.682 ± 0.02
1.579TyrGlu: 1.579 ± 0.019
1.206TyrPhe: 1.206 ± 0.017
2.078TyrGly: 2.078 ± 0.022
0.753TyrHis: 0.753 ± 0.013
1.479TyrIle: 1.479 ± 0.018
1.226TyrLys: 1.226 ± 0.016
2.603TyrLeu: 2.603 ± 0.026
0.699TyrMet: 0.699 ± 0.012
1.189TyrAsn: 1.189 ± 0.018
1.563TyrPro: 1.563 ± 0.024
1.159TyrGln: 1.159 ± 0.019
1.641TyrArg: 1.641 ± 0.019
2.101TyrSer: 2.101 ± 0.022
1.747TyrThr: 1.747 ± 0.021
1.658TyrVal: 1.658 ± 0.018
0.454TyrTrp: 0.454 ± 0.01
0.963TyrTyr: 0.963 ± 0.016
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 12174 proteins (5418225 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski