Amino acid dipepetide frequency for Dehalogenimonas formicexedens

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.931AlaAla: 10.931 ± 0.204	1.115AlaCys: 1.115 ± 0.049	4.896AlaAsp: 4.896 ± 0.094	6.219AlaGlu: 6.219 ± 0.106	3.396AlaPhe: 3.396 ± 0.083	8.437AlaGly: 8.437 ± 0.142	1.482AlaHis: 1.482 ± 0.053	6.308AlaIle: 6.308 ± 0.115	4.405AlaLys: 4.405 ± 0.092	9.29AlaLeu: 9.29 ± 0.131	2.512AlaMet: 2.512 ± 0.068	2.808AlaAsn: 2.808 ± 0.071	3.538AlaPro: 3.538 ± 0.086	2.841AlaGln: 2.841 ± 0.071	5.481AlaArg: 5.481 ± 0.106	5.73AlaSer: 5.73 ± 0.108	4.705AlaThr: 4.705 ± 0.122	7.544AlaVal: 7.544 ± 0.132	1.072AlaTrp: 1.072 ± 0.045	2.317AlaTyr: 2.317 ± 0.071	0.0AlaXaa: 0.0 ± 0.0
Cys	0.955CysAla: 0.955 ± 0.047	0.198CysCys: 0.198 ± 0.018	0.581CysAsp: 0.581 ± 0.033	0.52CysGlu: 0.52 ± 0.027	0.44CysPhe: 0.44 ± 0.032	1.372CysGly: 1.372 ± 0.048	0.422CysHis: 0.422 ± 0.032	0.527CysIle: 0.527 ± 0.031	0.479CysLys: 0.479 ± 0.031	1.028CysLeu: 1.028 ± 0.04	0.216CysMet: 0.216 ± 0.018	0.361CysAsn: 0.361 ± 0.023	0.904CysPro: 0.904 ± 0.046	0.431CysGln: 0.431 ± 0.024	0.866CysArg: 0.866 ± 0.044	0.632CysSer: 0.632 ± 0.036	0.486CysThr: 0.486 ± 0.027	0.693CysVal: 0.693 ± 0.033	0.14CysTrp: 0.14 ± 0.015	0.354CysTyr: 0.354 ± 0.023	0.0CysXaa: 0.0 ± 0.0
Asp	4.425AspAla: 4.425 ± 0.088	0.591AspCys: 0.591 ± 0.031	2.493AspAsp: 2.493 ± 0.076	3.477AspGlu: 3.477 ± 0.083	2.459AspPhe: 2.459 ± 0.068	3.72AspGly: 3.72 ± 0.09	0.896AspHis: 0.896 ± 0.036	3.915AspIle: 3.915 ± 0.088	2.642AspLys: 2.642 ± 0.066	5.369AspLeu: 5.369 ± 0.092	1.13AspMet: 1.13 ± 0.044	1.77AspAsn: 1.77 ± 0.053	2.65AspPro: 2.65 ± 0.076	1.426AspGln: 1.426 ± 0.047	2.884AspArg: 2.884 ± 0.077	2.795AspSer: 2.795 ± 0.059	2.586AspThr: 2.586 ± 0.06	3.491AspVal: 3.491 ± 0.084	0.73AspTrp: 0.73 ± 0.036	1.902AspTyr: 1.902 ± 0.066	0.0AspXaa: 0.0 ± 0.0
Glu	6.077GluAla: 6.077 ± 0.108	0.611GluCys: 0.611 ± 0.034	2.516GluAsp: 2.516 ± 0.069	3.832GluGlu: 3.832 ± 0.1	2.281GluPhe: 2.281 ± 0.058	3.813GluGly: 3.813 ± 0.088	1.159GluHis: 1.159 ± 0.051	4.526GluIle: 4.526 ± 0.098	3.964GluLys: 3.964 ± 0.094	6.532GluLeu: 6.532 ± 0.131	1.723GluMet: 1.723 ± 0.052	2.266GluAsn: 2.266 ± 0.068	2.345GluPro: 2.345 ± 0.067	2.049GluGln: 2.049 ± 0.071	3.771GluArg: 3.771 ± 0.097	3.59GluSer: 3.59 ± 0.074	3.745GluThr: 3.745 ± 0.098	4.313GluVal: 4.313 ± 0.094	0.649GluTrp: 0.649 ± 0.042	1.761GluTyr: 1.761 ± 0.06	0.0GluXaa: 0.0 ± 0.0
Phe	3.358PheAla: 3.358 ± 0.072	0.543PheCys: 0.543 ± 0.026	2.47PheAsp: 2.47 ± 0.065	2.302PheGlu: 2.302 ± 0.07	1.68PhePhe: 1.68 ± 0.067	3.473PheGly: 3.473 ± 0.077	0.805PheHis: 0.805 ± 0.036	2.854PheIle: 2.854 ± 0.073	2.072PheLys: 2.072 ± 0.061	3.58PheLeu: 3.58 ± 0.08	1.006PheMet: 1.006 ± 0.039	1.695PheAsn: 1.695 ± 0.051	1.749PhePro: 1.749 ± 0.05	1.164PheGln: 1.164 ± 0.044	2.088PheArg: 2.088 ± 0.063	2.729PheSer: 2.729 ± 0.077	2.482PheThr: 2.482 ± 0.065	2.666PheVal: 2.666 ± 0.067	0.535PheTrp: 0.535 ± 0.035	1.123PheTyr: 1.123 ± 0.042	0.0PheXaa: 0.0 ± 0.0
Gly	7.006GlyAla: 7.006 ± 0.146	1.097GlyCys: 1.097 ± 0.047	3.79GlyAsp: 3.79 ± 0.08	4.606GlyGlu: 4.606 ± 0.098	3.697GlyPhe: 3.697 ± 0.089	6.275GlyGly: 6.275 ± 0.146	1.65GlyHis: 1.65 ± 0.054	5.845GlyIle: 5.845 ± 0.106	4.605GlyLys: 4.605 ± 0.086	8.037GlyLeu: 8.037 ± 0.124	2.273GlyMet: 2.273 ± 0.063	2.655GlyAsn: 2.655 ± 0.078	2.485GlyPro: 2.485 ± 0.074	2.617GlyGln: 2.617 ± 0.063	4.425GlyArg: 4.425 ± 0.084	4.735GlySer: 4.735 ± 0.1	4.476GlyThr: 4.476 ± 0.127	5.916GlyVal: 5.916 ± 0.09	1.062GlyTrp: 1.062 ± 0.043	2.77GlyTyr: 2.77 ± 0.062	0.0GlyXaa: 0.0 ± 0.0
His	1.344HisAla: 1.344 ± 0.045	0.305HisCys: 0.305 ± 0.022	0.926HisAsp: 0.926 ± 0.037	0.982HisGlu: 0.982 ± 0.043	0.876HisPhe: 0.876 ± 0.043	1.482HisGly: 1.482 ± 0.05	0.484HisHis: 0.484 ± 0.03	1.122HisIle: 1.122 ± 0.049	0.784HisLys: 0.784 ± 0.039	2.101HisLeu: 2.101 ± 0.063	0.374HisMet: 0.374 ± 0.025	0.66HisAsn: 0.66 ± 0.036	1.303HisPro: 1.303 ± 0.054	0.716HisGln: 0.716 ± 0.036	1.225HisArg: 1.225 ± 0.05	1.082HisSer: 1.082 ± 0.039	0.901HisThr: 0.901 ± 0.041	1.126HisVal: 1.126 ± 0.052	0.255HisTrp: 0.255 ± 0.023	0.57HisTyr: 0.57 ± 0.029	0.0HisXaa: 0.0 ± 0.0
Ile	6.665IleAla: 6.665 ± 0.103	0.744IleCys: 0.744 ± 0.039	4.272IleAsp: 4.272 ± 0.082	4.409IleGlu: 4.409 ± 0.089	2.543IlePhe: 2.543 ± 0.065	5.514IleGly: 5.514 ± 0.113	1.168IleHis: 1.168 ± 0.046	4.621IleIle: 4.621 ± 0.093	3.34IleLys: 3.34 ± 0.082	6.079IleLeu: 6.079 ± 0.098	1.462IleMet: 1.462 ± 0.051	2.306IleAsn: 2.306 ± 0.068	3.188IlePro: 3.188 ± 0.083	1.726IleGln: 1.726 ± 0.061	3.417IleArg: 3.417 ± 0.071	4.279IleSer: 4.279 ± 0.084	4.004IleThr: 4.004 ± 0.099	4.76IleVal: 4.76 ± 0.088	0.664IleTrp: 0.664 ± 0.041	1.596IleTyr: 1.596 ± 0.055	0.0IleXaa: 0.0 ± 0.0
Lys	4.959LysAla: 4.959 ± 0.105	0.616LysCys: 0.616 ± 0.035	2.431LysAsp: 2.431 ± 0.059	3.348LysGlu: 3.348 ± 0.081	1.625LysPhe: 1.625 ± 0.054	3.577LysGly: 3.577 ± 0.089	0.891LysHis: 0.891 ± 0.039	3.365LysIle: 3.365 ± 0.067	3.004LysLys: 3.004 ± 0.086	5.015LysLeu: 5.015 ± 0.109	1.487LysMet: 1.487 ± 0.058	1.965LysAsn: 1.965 ± 0.057	2.729LysPro: 2.729 ± 0.061	1.665LysGln: 1.665 ± 0.046	2.903LysArg: 2.903 ± 0.079	3.025LysSer: 3.025 ± 0.076	3.348LysThr: 3.348 ± 0.076	3.661LysVal: 3.661 ± 0.08	0.555LysTrp: 0.555 ± 0.03	1.52LysTyr: 1.52 ± 0.055	0.0LysXaa: 0.0 ± 0.0
Leu	10.316LeuAla: 10.316 ± 0.153	0.97LeuCys: 0.97 ± 0.04	5.392LeuAsp: 5.392 ± 0.096	6.046LeuGlu: 6.046 ± 0.116	3.931LeuPhe: 3.931 ± 0.09	8.154LeuGly: 8.154 ± 0.128	1.555LeuHis: 1.555 ± 0.047	6.217LeuIle: 6.217 ± 0.112	6.034LeuLys: 6.034 ± 0.113	8.944LeuLeu: 8.944 ± 0.152	1.998LeuMet: 1.998 ± 0.055	3.526LeuAsn: 3.526 ± 0.077	5.102LeuPro: 5.102 ± 0.099	2.508LeuGln: 2.508 ± 0.07	5.287LeuArg: 5.287 ± 0.106	6.998LeuSer: 6.998 ± 0.107	5.545LeuThr: 5.545 ± 0.107	7.133LeuVal: 7.133 ± 0.12	0.998LeuTrp: 0.998 ± 0.051	2.154LeuTyr: 2.154 ± 0.057	0.0LeuXaa: 0.0 ± 0.0
Met	2.787MetAla: 2.787 ± 0.067	0.17MetCys: 0.17 ± 0.02	1.158MetAsp: 1.158 ± 0.037	1.271MetGlu: 1.271 ± 0.044	0.827MetPhe: 0.827 ± 0.041	1.756MetGly: 1.756 ± 0.064	0.329MetHis: 0.329 ± 0.024	1.357MetIle: 1.357 ± 0.049	1.5MetLys: 1.5 ± 0.051	2.342MetLeu: 2.342 ± 0.067	0.71MetMet: 0.71 ± 0.042	0.986MetAsn: 0.986 ± 0.035	1.545MetPro: 1.545 ± 0.047	0.571MetGln: 0.571 ± 0.033	1.248MetArg: 1.248 ± 0.043	1.56MetSer: 1.56 ± 0.048	1.634MetThr: 1.634 ± 0.053	2.006MetVal: 2.006 ± 0.069	0.209MetTrp: 0.209 ± 0.019	0.473MetTyr: 0.473 ± 0.029	0.0MetXaa: 0.0 ± 0.0
Asn	2.861AsnAla: 2.861 ± 0.074	0.433AsnCys: 0.433 ± 0.031	1.581AsnAsp: 1.581 ± 0.055	1.833AsnGlu: 1.833 ± 0.06	1.313AsnPhe: 1.313 ± 0.045	2.656AsnGly: 2.656 ± 0.085	0.692AsnHis: 0.692 ± 0.035	2.477AsnIle: 2.477 ± 0.067	1.507AsnLys: 1.507 ± 0.056	3.674AsnLeu: 3.674 ± 0.074	0.749AsnMet: 0.749 ± 0.032	1.281AsnAsn: 1.281 ± 0.053	2.398AsnPro: 2.398 ± 0.059	1.057AsnGln: 1.057 ± 0.038	2.197AsnArg: 2.197 ± 0.065	1.988AsnSer: 1.988 ± 0.07	1.957AsnThr: 1.957 ± 0.067	2.291AsnVal: 2.291 ± 0.066	0.494AsnTrp: 0.494 ± 0.03	1.143AsnTyr: 1.143 ± 0.047	0.0AsnXaa: 0.0 ± 0.0
Pro	4.419ProAla: 4.419 ± 0.105	0.435ProCys: 0.435 ± 0.029	3.012ProAsp: 3.012 ± 0.076	3.944ProGlu: 3.944 ± 0.083	1.904ProPhe: 1.904 ± 0.061	4.341ProGly: 4.341 ± 0.133	0.772ProHis: 0.772 ± 0.037	2.479ProIle: 2.479 ± 0.061	2.101ProLys: 2.101 ± 0.052	4.132ProLeu: 4.132 ± 0.076	1.13ProMet: 1.13 ± 0.047	1.586ProAsn: 1.586 ± 0.053	2.437ProPro: 2.437 ± 0.083	1.556ProGln: 1.556 ± 0.051	2.156ProArg: 2.156 ± 0.062	2.964ProSer: 2.964 ± 0.072	2.51ProThr: 2.51 ± 0.078	4.234ProVal: 4.234 ± 0.087	0.591ProTrp: 0.591 ± 0.047	1.217ProTyr: 1.217 ± 0.044	0.0ProXaa: 0.0 ± 0.0
Gln	3.412GlnAla: 3.412 ± 0.071	0.288GlnCys: 0.288 ± 0.023	1.294GlnAsp: 1.294 ± 0.053	1.779GlnGlu: 1.779 ± 0.056	1.061GlnPhe: 1.061 ± 0.049	2.039GlnGly: 2.039 ± 0.055	0.603GlnHis: 0.603 ± 0.034	2.016GlnIle: 2.016 ± 0.062	1.718GlnLys: 1.718 ± 0.054	2.933GlnLeu: 2.933 ± 0.077	0.799GlnMet: 0.799 ± 0.039	1.22GlnAsn: 1.22 ± 0.043	1.569GlnPro: 1.569 ± 0.057	1.034GlnGln: 1.034 ± 0.049	1.734GlnArg: 1.734 ± 0.061	1.929GlnSer: 1.929 ± 0.057	1.683GlnThr: 1.683 ± 0.049	2.348GlnVal: 2.348 ± 0.065	0.341GlnTrp: 0.341 ± 0.026	0.794GlnTyr: 0.794 ± 0.038	0.0GlnXaa: 0.0 ± 0.0
Arg	4.407ArgAla: 4.407 ± 0.088	0.746ArgCys: 0.746 ± 0.039	2.908ArgAsp: 2.908 ± 0.071	3.687ArgGlu: 3.687 ± 0.085	2.406ArgPhe: 2.406 ± 0.061	3.803ArgGly: 3.803 ± 0.081	1.327ArgHis: 1.327 ± 0.05	3.806ArgIle: 3.806 ± 0.087	2.902ArgLys: 2.902 ± 0.079	6.482ArgLeu: 6.482 ± 0.139	1.444ArgMet: 1.444 ± 0.046	1.79ArgAsn: 1.79 ± 0.057	2.375ArgPro: 2.375 ± 0.061	2.243ArgGln: 2.243 ± 0.058	4.042ArgArg: 4.042 ± 0.1	3.183ArgSer: 3.183 ± 0.088	2.625ArgThr: 2.625 ± 0.056	3.972ArgVal: 3.972 ± 0.093	0.693ArgTrp: 0.693 ± 0.032	1.859ArgTyr: 1.859 ± 0.056	0.0ArgXaa: 0.0 ± 0.0
Ser	5.374SerAla: 5.374 ± 0.11	0.725SerCys: 0.725 ± 0.04	2.877SerAsp: 2.877 ± 0.064	3.506SerGlu: 3.506 ± 0.077	2.661SerPhe: 2.661 ± 0.067	6.039SerGly: 6.039 ± 0.123	1.29SerHis: 1.29 ± 0.049	4.032SerIle: 4.032 ± 0.09	2.793SerLys: 2.793 ± 0.075	6.484SerLeu: 6.484 ± 0.116	1.443SerMet: 1.443 ± 0.049	1.828SerAsn: 1.828 ± 0.053	3.065SerPro: 3.065 ± 0.074	2.054SerGln: 2.054 ± 0.07	3.796SerArg: 3.796 ± 0.086	3.671SerSer: 3.671 ± 0.084	3.152SerThr: 3.152 ± 0.078	4.425SerVal: 4.425 ± 0.088	0.634SerTrp: 0.634 ± 0.033	1.601SerTyr: 1.601 ± 0.058	0.0SerXaa: 0.0 ± 0.0
Thr	5.399ThrAla: 5.399 ± 0.111	0.581ThrCys: 0.581 ± 0.034	2.925ThrAsp: 2.925 ± 0.072	3.254ThrGlu: 3.254 ± 0.085	2.179ThrPhe: 2.179 ± 0.067	5.563ThrGly: 5.563 ± 0.096	0.963ThrHis: 0.963 ± 0.044	3.559ThrIle: 3.559 ± 0.077	2.215ThrLys: 2.215 ± 0.071	5.351ThrLeu: 5.351 ± 0.102	1.222ThrMet: 1.222 ± 0.042	1.858ThrAsn: 1.858 ± 0.068	3.137ThrPro: 3.137 ± 0.073	1.523ThrGln: 1.523 ± 0.045	2.875ThrArg: 2.875 ± 0.072	3.378ThrSer: 3.378 ± 0.083	3.2ThrThr: 3.2 ± 0.128	4.504ThrVal: 4.504 ± 0.124	0.614ThrTrp: 0.614 ± 0.029	1.512ThrTyr: 1.512 ± 0.052	0.0ThrXaa: 0.0 ± 0.0
Val	7.292ValAla: 7.292 ± 0.122	0.833ValCys: 0.833 ± 0.036	3.689ValAsp: 3.689 ± 0.079	4.359ValGlu: 4.359 ± 0.083	3.261ValPhe: 3.261 ± 0.078	4.949ValGly: 4.949 ± 0.104	1.229ValHis: 1.229 ± 0.05	5.499ValIle: 5.499 ± 0.104	3.962ValLys: 3.962 ± 0.087	6.963ValLeu: 6.963 ± 0.123	1.907ValMet: 1.907 ± 0.054	2.541ValAsn: 2.541 ± 0.068	3.449ValPro: 3.449 ± 0.085	1.662ValGln: 1.662 ± 0.062	3.692ValArg: 3.692 ± 0.073	4.919ValSer: 4.919 ± 0.091	4.735ValThr: 4.735 ± 0.106	5.651ValVal: 5.651 ± 0.102	0.805ValTrp: 0.805 ± 0.039	1.877ValTyr: 1.877 ± 0.056	0.0ValXaa: 0.0 ± 0.0
Trp	0.861TrpAla: 0.861 ± 0.044	0.132TrpCys: 0.132 ± 0.014	0.619TrpAsp: 0.619 ± 0.03	0.595TrpGlu: 0.595 ± 0.035	0.489TrpPhe: 0.489 ± 0.031	0.912TrpGly: 0.912 ± 0.036	0.26TrpHis: 0.26 ± 0.023	0.693TrpIle: 0.693 ± 0.039	0.524TrpLys: 0.524 ± 0.028	1.365TrpLeu: 1.365 ± 0.056	0.308TrpMet: 0.308 ± 0.026	0.487TrpAsn: 0.487 ± 0.03	0.504TrpPro: 0.504 ± 0.026	0.659TrpGln: 0.659 ± 0.036	0.771TrpArg: 0.771 ± 0.035	0.532TrpSer: 0.532 ± 0.03	0.522TrpThr: 0.522 ± 0.043	0.833TrpVal: 0.833 ± 0.035	0.272TrpTrp: 0.272 ± 0.022	0.343TrpTyr: 0.343 ± 0.027	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.179TyrAla: 2.179 ± 0.059	0.473TyrCys: 0.473 ± 0.026	1.518TyrAsp: 1.518 ± 0.049	1.553TyrGlu: 1.553 ± 0.051	1.349TyrPhe: 1.349 ± 0.046	2.148TyrGly: 2.148 ± 0.056	0.641TyrHis: 0.641 ± 0.033	1.54TyrIle: 1.54 ± 0.057	1.138TyrLys: 1.138 ± 0.045	3.106TyrLeu: 3.106 ± 0.07	0.545TyrMet: 0.545 ± 0.03	0.991TyrAsn: 0.991 ± 0.043	1.449TyrPro: 1.449 ± 0.059	1.09TyrGln: 1.09 ± 0.048	1.843TyrArg: 1.843 ± 0.057	1.731TyrSer: 1.731 ± 0.056	1.518TyrThr: 1.518 ± 0.053	1.706TyrVal: 1.706 ± 0.052	0.367TyrTrp: 0.367 ± 0.025	0.879TyrTyr: 0.879 ± 0.047	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2117 proteins (607201 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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