Amino acid dipepetide frequency for Setosphaeria turcica (strain 28A) (Northern leaf blight fungus) (Exserohilum turcicum)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	10.022AlaAla: 10.022 ± 0.067	1.181AlaCys: 1.181 ± 0.013	4.493AlaAsp: 4.493 ± 0.034	5.285AlaGlu: 5.285 ± 0.038	3.212AlaPhe: 3.212 ± 0.025	5.876AlaGly: 5.876 ± 0.041	2.142AlaHis: 2.142 ± 0.02	4.293AlaIle: 4.293 ± 0.029	4.567AlaLys: 4.567 ± 0.038	7.983AlaLeu: 7.983 ± 0.043	2.161AlaMet: 2.161 ± 0.021	3.27AlaAsn: 3.27 ± 0.027	5.555AlaPro: 5.555 ± 0.046	3.907AlaGln: 3.907 ± 0.03	5.271AlaArg: 5.271 ± 0.038	7.796AlaSer: 7.796 ± 0.047	5.59AlaThr: 5.59 ± 0.036	5.439AlaVal: 5.439 ± 0.034	1.241AlaTrp: 1.241 ± 0.017	2.373AlaTyr: 2.373 ± 0.024	0.0AlaXaa: 0.0 ± 0.0
Cys	1.053CysAla: 1.053 ± 0.015	0.262CysCys: 0.262 ± 0.008	0.672CysAsp: 0.672 ± 0.012	0.611CysGlu: 0.611 ± 0.011	0.541CysPhe: 0.541 ± 0.011	0.964CysGly: 0.964 ± 0.017	0.326CysHis: 0.326 ± 0.01	0.747CysIle: 0.747 ± 0.012	0.564CysLys: 0.564 ± 0.01	1.176CysLeu: 1.176 ± 0.014	0.314CysMet: 0.314 ± 0.008	0.464CysAsn: 0.464 ± 0.009	0.672CysPro: 0.672 ± 0.012	0.452CysGln: 0.452 ± 0.01	0.749CysArg: 0.749 ± 0.013	0.931CysSer: 0.931 ± 0.016	0.748CysThr: 0.748 ± 0.013	0.814CysVal: 0.814 ± 0.015	0.205CysTrp: 0.205 ± 0.007	0.372CysTyr: 0.372 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	5.425AspAla: 5.425 ± 0.031	0.628AspCys: 0.628 ± 0.011	4.416AspAsp: 4.416 ± 0.05	4.46AspGlu: 4.46 ± 0.04	2.181AspPhe: 2.181 ± 0.021	3.88AspGly: 3.88 ± 0.033	1.235AspHis: 1.235 ± 0.015	2.934AspIle: 2.934 ± 0.024	2.51AspLys: 2.51 ± 0.026	4.648AspLeu: 4.648 ± 0.032	1.474AspMet: 1.474 ± 0.017	1.82AspAsn: 1.82 ± 0.02	3.143AspPro: 3.143 ± 0.027	1.825AspGln: 1.825 ± 0.019	2.901AspArg: 2.901 ± 0.028	3.874AspSer: 3.874 ± 0.029	3.109AspThr: 3.109 ± 0.026	3.749AspVal: 3.749 ± 0.032	0.908AspTrp: 0.908 ± 0.014	1.607AspTyr: 1.607 ± 0.019	0.0AspXaa: 0.0 ± 0.0
Glu	5.651GluAla: 5.651 ± 0.047	0.642GluCys: 0.642 ± 0.013	4.076GluAsp: 4.076 ± 0.039	5.266GluGlu: 5.266 ± 0.06	1.838GluPhe: 1.838 ± 0.02	3.574GluGly: 3.574 ± 0.033	1.565GluHis: 1.565 ± 0.018	2.836GluIle: 2.836 ± 0.028	3.783GluLys: 3.783 ± 0.033	4.963GluLeu: 4.963 ± 0.037	1.479GluMet: 1.479 ± 0.02	2.138GluAsn: 2.138 ± 0.023	2.827GluPro: 2.827 ± 0.049	2.68GluGln: 2.68 ± 0.026	3.954GluArg: 3.954 ± 0.035	3.921GluSer: 3.921 ± 0.027	3.283GluThr: 3.283 ± 0.024	3.317GluVal: 3.317 ± 0.029	0.907GluTrp: 0.907 ± 0.013	1.685GluTyr: 1.685 ± 0.019	0.0GluXaa: 0.0 ± 0.0
Phe	3.179PheAla: 3.179 ± 0.028	0.541PheCys: 0.541 ± 0.011	2.24PheAsp: 2.24 ± 0.019	2.075PheGlu: 2.075 ± 0.022	1.556PhePhe: 1.556 ± 0.022	2.812PheGly: 2.812 ± 0.027	0.872PheHis: 0.872 ± 0.013	1.668PheIle: 1.668 ± 0.022	1.543PheLys: 1.543 ± 0.018	3.211PheLeu: 3.211 ± 0.029	0.776PheMet: 0.776 ± 0.013	1.421PheAsn: 1.421 ± 0.018	1.871PhePro: 1.871 ± 0.019	1.343PheGln: 1.343 ± 0.017	1.858PheArg: 1.858 ± 0.021	2.909PheSer: 2.909 ± 0.024	2.148PheThr: 2.148 ± 0.021	2.343PheVal: 2.343 ± 0.026	0.629PheTrp: 0.629 ± 0.012	1.061PheTyr: 1.061 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	5.555GlyAla: 5.555 ± 0.042	0.903GlyCys: 0.903 ± 0.015	3.507GlyAsp: 3.507 ± 0.028	3.525GlyGlu: 3.525 ± 0.029	2.727GlyPhe: 2.727 ± 0.025	5.757GlyGly: 5.757 ± 0.059	1.708GlyHis: 1.708 ± 0.022	3.405GlyIle: 3.405 ± 0.028	3.512GlyLys: 3.512 ± 0.031	5.754GlyLeu: 5.754 ± 0.038	1.664GlyMet: 1.664 ± 0.018	2.485GlyAsn: 2.485 ± 0.025	3.291GlyPro: 3.291 ± 0.028	2.538GlyGln: 2.538 ± 0.029	3.999GlyArg: 3.999 ± 0.032	5.341GlySer: 5.341 ± 0.04	3.916GlyThr: 3.916 ± 0.03	4.262GlyVal: 4.262 ± 0.031	1.146GlyTrp: 1.146 ± 0.016	2.142GlyTyr: 2.142 ± 0.024	0.0GlyXaa: 0.0 ± 0.0
His	2.28HisAla: 2.28 ± 0.02	0.356HisCys: 0.356 ± 0.008	1.467HisAsp: 1.467 ± 0.018	1.435HisGlu: 1.435 ± 0.017	0.925HisPhe: 0.925 ± 0.013	1.847HisGly: 1.847 ± 0.02	0.954HisHis: 0.954 ± 0.018	1.223HisIle: 1.223 ± 0.017	0.995HisLys: 0.995 ± 0.013	2.234HisLeu: 2.234 ± 0.021	0.583HisMet: 0.583 ± 0.011	0.9HisAsn: 0.9 ± 0.014	1.654HisPro: 1.654 ± 0.018	1.077HisGln: 1.077 ± 0.014	1.538HisArg: 1.538 ± 0.018	1.93HisSer: 1.93 ± 0.026	1.447HisThr: 1.447 ± 0.019	1.657HisVal: 1.657 ± 0.017	0.351HisTrp: 0.351 ± 0.008	0.732HisTyr: 0.732 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	4.356IleAla: 4.356 ± 0.033	0.728IleCys: 0.728 ± 0.013	2.77IleAsp: 2.77 ± 0.026	2.797IleGlu: 2.797 ± 0.024	1.844IlePhe: 1.844 ± 0.021	3.039IleGly: 3.039 ± 0.029	1.18IleHis: 1.18 ± 0.016	2.323IleIle: 2.323 ± 0.024	2.24IleLys: 2.24 ± 0.024	4.198IleLeu: 4.198 ± 0.034	1.028IleMet: 1.028 ± 0.014	1.722IleAsn: 1.722 ± 0.021	2.906IlePro: 2.906 ± 0.022	1.893IleGln: 1.893 ± 0.018	2.658IleArg: 2.658 ± 0.022	3.482IleSer: 3.482 ± 0.026	2.816IleThr: 2.816 ± 0.026	3.093IleVal: 3.093 ± 0.026	0.712IleTrp: 0.712 ± 0.013	1.358IleTyr: 1.358 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.587LysAla: 4.587 ± 0.041	0.526LysCys: 0.526 ± 0.011	2.968LysAsp: 2.968 ± 0.022	3.518LysGlu: 3.518 ± 0.038	1.433LysPhe: 1.433 ± 0.02	3.08LysGly: 3.08 ± 0.026	1.263LysHis: 1.263 ± 0.017	2.238LysIle: 2.238 ± 0.022	3.657LysLys: 3.657 ± 0.052	4.108LysLeu: 4.108 ± 0.032	1.103LysMet: 1.103 ± 0.014	1.837LysAsn: 1.837 ± 0.019	2.967LysPro: 2.967 ± 0.033	2.089LysGln: 2.089 ± 0.025	3.543LysArg: 3.543 ± 0.034	3.464LysSer: 3.464 ± 0.03	2.963LysThr: 2.963 ± 0.024	2.738LysVal: 2.738 ± 0.026	0.711LysTrp: 0.711 ± 0.012	1.394LysTyr: 1.394 ± 0.017	0.0LysXaa: 0.0 ± 0.0
Leu	7.893LeuAla: 7.893 ± 0.048	1.229LeuCys: 1.229 ± 0.017	5.035LeuAsp: 5.035 ± 0.034	5.243LeuGlu: 5.243 ± 0.036	3.168LeuPhe: 3.168 ± 0.03	5.646LeuGly: 5.646 ± 0.039	2.346LeuHis: 2.346 ± 0.025	3.643LeuIle: 3.643 ± 0.029	4.17LeuLys: 4.17 ± 0.029	7.947LeuLeu: 7.947 ± 0.062	1.762LeuMet: 1.762 ± 0.02	3.057LeuAsn: 3.057 ± 0.022	5.405LeuPro: 5.405 ± 0.038	3.874LeuGln: 3.874 ± 0.035	5.536LeuArg: 5.536 ± 0.036	6.869LeuSer: 6.869 ± 0.034	4.581LeuThr: 4.581 ± 0.03	5.295LeuVal: 5.295 ± 0.036	1.159LeuTrp: 1.159 ± 0.015	2.324LeuTyr: 2.324 ± 0.022	0.0LeuXaa: 0.0 ± 0.0
Met	2.382MetAla: 2.382 ± 0.023	0.277MetCys: 0.277 ± 0.007	1.341MetAsp: 1.341 ± 0.018	1.281MetGlu: 1.281 ± 0.016	0.771MetPhe: 0.771 ± 0.013	1.531MetGly: 1.531 ± 0.018	0.59MetHis: 0.59 ± 0.01	0.946MetIle: 0.946 ± 0.015	1.038MetLys: 1.038 ± 0.015	1.985MetLeu: 1.985 ± 0.021	0.609MetMet: 0.609 ± 0.013	0.806MetAsn: 0.806 ± 0.015	1.413MetPro: 1.413 ± 0.017	1.036MetGln: 1.036 ± 0.016	1.371MetArg: 1.371 ± 0.014	1.928MetSer: 1.928 ± 0.019	1.318MetThr: 1.318 ± 0.015	1.337MetVal: 1.337 ± 0.017	0.278MetTrp: 0.278 ± 0.007	0.607MetTyr: 0.607 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.412AsnAla: 3.412 ± 0.025	0.444AsnCys: 0.444 ± 0.01	1.91AsnAsp: 1.91 ± 0.018	1.967AsnGlu: 1.967 ± 0.023	1.336AsnPhe: 1.336 ± 0.016	2.973AsnGly: 2.973 ± 0.035	0.86AsnHis: 0.86 ± 0.012	1.971AsnIle: 1.971 ± 0.021	1.717AsnLys: 1.717 ± 0.018	3.031AsnLeu: 3.031 ± 0.027	0.935AsnMet: 0.935 ± 0.013	1.577AsnAsn: 1.577 ± 0.027	2.375AsnPro: 2.375 ± 0.024	1.357AsnGln: 1.357 ± 0.018	1.859AsnArg: 1.859 ± 0.019	2.657AsnSer: 2.657 ± 0.027	2.313AsnThr: 2.313 ± 0.024	2.347AsnVal: 2.347 ± 0.02	0.551AsnTrp: 0.551 ± 0.011	1.035AsnTyr: 1.035 ± 0.014	0.0AsnXaa: 0.0 ± 0.0
Pro	5.882ProAla: 5.882 ± 0.049	0.57ProCys: 0.57 ± 0.013	3.167ProAsp: 3.167 ± 0.024	3.701ProGlu: 3.701 ± 0.047	2.009ProPhe: 2.009 ± 0.021	3.804ProGly: 3.804 ± 0.031	1.522ProHis: 1.522 ± 0.017	2.481ProIle: 2.481 ± 0.023	2.86ProLys: 2.86 ± 0.028	4.694ProLeu: 4.694 ± 0.031	1.178ProMet: 1.178 ± 0.016	2.247ProAsn: 2.247 ± 0.026	5.56ProPro: 5.56 ± 0.077	2.67ProGln: 2.67 ± 0.032	3.487ProArg: 3.487 ± 0.031	5.939ProSer: 5.939 ± 0.047	4.123ProThr: 4.123 ± 0.032	3.551ProVal: 3.551 ± 0.03	0.745ProTrp: 0.745 ± 0.013	1.605ProTyr: 1.605 ± 0.017	0.0ProXaa: 0.0 ± 0.0
Gln	3.754GlnAla: 3.754 ± 0.031	0.47GlnCys: 0.47 ± 0.009	2.266GlnAsp: 2.266 ± 0.019	2.448GlnGlu: 2.448 ± 0.026	1.273GlnPhe: 1.273 ± 0.016	2.482GlnGly: 2.482 ± 0.024	1.306GlnHis: 1.306 ± 0.016	1.84GlnIle: 1.84 ± 0.02	2.078GlnLys: 2.078 ± 0.022	3.473GlnLeu: 3.473 ± 0.028	0.933GlnMet: 0.933 ± 0.012	1.606GlnAsn: 1.606 ± 0.017	2.718GlnPro: 2.718 ± 0.033	2.906GlnGln: 2.906 ± 0.059	2.809GlnArg: 2.809 ± 0.027	3.147GlnSer: 3.147 ± 0.027	2.344GlnThr: 2.344 ± 0.021	2.196GlnVal: 2.196 ± 0.021	0.607GlnTrp: 0.607 ± 0.011	1.247GlnTyr: 1.247 ± 0.015	0.0GlnXaa: 0.0 ± 0.0
Arg	4.902ArgAla: 4.902 ± 0.038	0.726ArgCys: 0.726 ± 0.011	3.294ArgAsp: 3.294 ± 0.027	3.689ArgGlu: 3.689 ± 0.03	2.095ArgPhe: 2.095 ± 0.021	3.645ArgGly: 3.645 ± 0.035	1.629ArgHis: 1.629 ± 0.018	2.952ArgIle: 2.952 ± 0.023	3.555ArgLys: 3.555 ± 0.033	5.391ArgLeu: 5.391 ± 0.04	1.383ArgMet: 1.383 ± 0.016	2.318ArgAsn: 2.318 ± 0.02	3.595ArgPro: 3.595 ± 0.033	2.627ArgGln: 2.627 ± 0.025	4.978ArgArg: 4.978 ± 0.046	4.61ArgSer: 4.61 ± 0.04	3.339ArgThr: 3.339 ± 0.03	3.28ArgVal: 3.28 ± 0.026	0.89ArgTrp: 0.89 ± 0.015	1.654ArgTyr: 1.654 ± 0.015	0.0ArgXaa: 0.0 ± 0.0
Ser	6.901SerAla: 6.901 ± 0.049	0.87SerCys: 0.87 ± 0.014	4.106SerAsp: 4.106 ± 0.035	3.967SerGlu: 3.967 ± 0.033	2.837SerPhe: 2.837 ± 0.025	5.254SerGly: 5.254 ± 0.034	2.018SerHis: 2.018 ± 0.024	3.793SerIle: 3.793 ± 0.031	3.73SerLys: 3.73 ± 0.028	6.765SerLeu: 6.765 ± 0.046	1.79SerMet: 1.79 ± 0.02	2.92SerAsn: 2.92 ± 0.023	5.53SerPro: 5.53 ± 0.045	3.212SerGln: 3.212 ± 0.033	4.766SerArg: 4.766 ± 0.04	8.253SerSer: 8.253 ± 0.069	5.505SerThr: 5.505 ± 0.044	4.443SerVal: 4.443 ± 0.03	1.05SerTrp: 1.05 ± 0.014	2.052SerTyr: 2.052 ± 0.02	0.0SerXaa: 0.0 ± 0.0
Thr	5.527ThrAla: 5.527 ± 0.035	0.812ThrCys: 0.812 ± 0.014	2.811ThrAsp: 2.811 ± 0.024	2.945ThrGlu: 2.945 ± 0.025	2.194ThrPhe: 2.194 ± 0.022	4.059ThrGly: 4.059 ± 0.032	1.442ThrHis: 1.442 ± 0.018	2.956ThrIle: 2.956 ± 0.028	2.753ThrLys: 2.753 ± 0.024	5.255ThrLeu: 5.255 ± 0.034	1.26ThrMet: 1.26 ± 0.016	2.141ThrAsn: 2.141 ± 0.022	4.604ThrPro: 4.604 ± 0.037	2.215ThrGln: 2.215 ± 0.024	3.244ThrArg: 3.244 ± 0.028	5.174ThrSer: 5.174 ± 0.039	4.375ThrThr: 4.375 ± 0.04	3.657ThrVal: 3.657 ± 0.028	0.881ThrTrp: 0.881 ± 0.014	1.625ThrTyr: 1.625 ± 0.018	0.0ThrXaa: 0.0 ± 0.0
Val	5.424ValAla: 5.424 ± 0.031	0.84ValCys: 0.84 ± 0.013	3.595ValAsp: 3.595 ± 0.03	3.809ValGlu: 3.809 ± 0.026	2.391ValPhe: 2.391 ± 0.025	3.933ValGly: 3.933 ± 0.033	1.468ValHis: 1.468 ± 0.018	2.752ValIle: 2.752 ± 0.023	2.929ValLys: 2.929 ± 0.028	5.478ValLeu: 5.478 ± 0.041	1.347ValMet: 1.347 ± 0.016	2.127ValAsn: 2.127 ± 0.023	3.562ValPro: 3.562 ± 0.029	2.495ValGln: 2.495 ± 0.023	3.427ValArg: 3.427 ± 0.027	4.46ValSer: 4.46 ± 0.031	3.39ValThr: 3.39 ± 0.027	4.265ValVal: 4.265 ± 0.037	0.871ValTrp: 0.871 ± 0.012	1.747ValTyr: 1.747 ± 0.019	0.0ValXaa: 0.0 ± 0.0
Trp	1.153TrpAla: 1.153 ± 0.018	0.208TrpCys: 0.208 ± 0.007	0.916TrpAsp: 0.916 ± 0.015	0.821TrpGlu: 0.821 ± 0.012	0.543TrpPhe: 0.543 ± 0.01	0.921TrpGly: 0.921 ± 0.014	0.386TrpHis: 0.386 ± 0.009	0.756TrpIle: 0.756 ± 0.014	0.804TrpLys: 0.804 ± 0.014	1.327TrpLeu: 1.327 ± 0.018	0.367TrpMet: 0.367 ± 0.009	0.624TrpAsn: 0.624 ± 0.01	0.62TrpPro: 0.62 ± 0.01	0.59TrpGln: 0.59 ± 0.009	0.968TrpArg: 0.968 ± 0.013	1.052TrpSer: 1.052 ± 0.015	0.914TrpThr: 0.914 ± 0.013	0.88TrpVal: 0.88 ± 0.013	0.278TrpTrp: 0.278 ± 0.008	0.444TrpTyr: 0.444 ± 0.011	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.319TyrAla: 2.319 ± 0.024	0.424TyrCys: 0.424 ± 0.009	1.676TyrAsp: 1.676 ± 0.019	1.543TyrGlu: 1.543 ± 0.017	1.18TyrPhe: 1.18 ± 0.018	2.061TyrGly: 2.061 ± 0.024	0.773TyrHis: 0.773 ± 0.013	1.386TyrIle: 1.386 ± 0.017	1.183TyrLys: 1.183 ± 0.015	2.562TyrLeu: 2.562 ± 0.024	0.699TyrMet: 0.699 ± 0.013	1.148TyrAsn: 1.148 ± 0.017	1.525TyrPro: 1.525 ± 0.018	1.12TyrGln: 1.12 ± 0.016	1.635TyrArg: 1.635 ± 0.018	2.025TyrSer: 2.025 ± 0.02	1.71TyrThr: 1.71 ± 0.019	1.643TyrVal: 1.643 ± 0.019	0.451TyrTrp: 0.451 ± 0.01	0.951TyrTyr: 0.951 ± 0.015	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 11687 proteins (5320234 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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