Ophiophagus hannah (King cobra) (Naja hannah)

Taxonomy: cellular organisms; Eukaryota; Opisthokonta; Metazoa; Eumetazoa; Bilateria; Deuterostomia; Chordata; Craniata; Vertebrata; Gnathostomata; Teleostomi; Euteleostomi; Sarcopterygii; Dipnotetrapodomorpha; Tetrapoda; Amniota; Sauropsida; Sauria; Lepidosauria;

Average proteome isoelectric point is 6.89

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 18387 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|V8NVU6|V8NVU6_OPHHA Mastermind-like protein 2 (Fragment) OS=Ophiophagus hannah OX=8665 GN=MAML2 PE=4 SV=1
MM1 pKa = 7.49PQNCLSFQFNSDD13 pKa = 3.05SSEE16 pKa = 3.83EE17 pKa = 4.26GFGGNSSEE25 pKa = 4.27EE26 pKa = 4.16EE27 pKa = 4.09EE28 pKa = 4.39EE29 pKa = 4.42EE30 pKa = 4.63EE31 pKa = 4.48GGQSNEE37 pKa = 3.87EE38 pKa = 4.01NEE40 pKa = 4.28GGKK43 pKa = 10.49GSEE46 pKa = 4.33EE47 pKa = 4.05TTVAPTTPAAGDD59 pKa = 3.68TNTDD63 pKa = 3.38GNAEE67 pKa = 4.4PPTEE71 pKa = 4.2VPGVKK76 pKa = 10.24DD77 pKa = 3.62PLQKK81 pKa = 10.09PGKK84 pKa = 9.47EE85 pKa = 4.2GGDD88 pKa = 3.31KK89 pKa = 10.87KK90 pKa = 11.24VDD92 pKa = 3.41NAPKK96 pKa = 10.23KK97 pKa = 9.49GAKK100 pKa = 10.02EE101 pKa = 3.73EE102 pKa = 4.61DD103 pKa = 3.22SDD105 pKa = 4.36EE106 pKa = 4.54NEE108 pKa = 3.93EE109 pKa = 4.17EE110 pKa = 4.17EE111 pKa = 4.39NEE113 pKa = 4.09EE114 pKa = 3.99EE115 pKa = 4.23EE116 pKa = 4.45EE117 pKa = 4.33EE118 pKa = 4.37KK119 pKa = 10.95VDD121 pKa = 4.42EE122 pKa = 4.88NGSGANGTSTNSTLEE137 pKa = 3.82EE138 pKa = 4.04TGNGGEE144 pKa = 4.13EE145 pKa = 4.18EE146 pKa = 4.15EE147 pKa = 4.48EE148 pKa = 4.39EE149 pKa = 4.23EE150 pKa = 4.99NEE152 pKa = 3.89ATTISLTTLVTTVNPTEE169 pKa = 4.35STTGEE174 pKa = 3.69QWQDD178 pKa = 2.89GTSPADD184 pKa = 3.06QGQYY188 pKa = 9.07DD189 pKa = 4.07TEE191 pKa = 4.61DD192 pKa = 3.54PWVHH196 pKa = 7.29DD197 pKa = 3.55ATTTNGYY204 pKa = 8.85EE205 pKa = 4.12VQTDD209 pKa = 4.24YY210 pKa = 11.61YY211 pKa = 10.41GSEE214 pKa = 3.71NGYY217 pKa = 9.47PRR219 pKa = 11.84GDD221 pKa = 3.22NFRR224 pKa = 11.84TYY226 pKa = 10.58EE227 pKa = 4.32DD228 pKa = 3.88EE229 pKa = 3.79YY230 pKa = 11.4SYY232 pKa = 11.73YY233 pKa = 10.2KK234 pKa = 10.32GHH236 pKa = 6.87GYY238 pKa = 10.38DD239 pKa = 4.46VYY241 pKa = 11.4GQDD244 pKa = 3.42YY245 pKa = 10.51YY246 pKa = 12.03YY247 pKa = 11.17NQQ249 pKa = 3.36

Molecular weight: 27.19 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|V8P534|V8P534_OPHHA Polypyrimidine tract-binding protein 1 OS=Ophiophagus hannah OX=8665 GN=PTBP1 PE=4 SV=1
MM1 pKa = 7.48FSDD4 pKa = 3.81TVSYY8 pKa = 10.56KK9 pKa = 10.16VAIYY13 pKa = 8.43SHH15 pKa = 5.7WQARR19 pKa = 11.84TLGKK23 pKa = 10.43RR24 pKa = 11.84SDD26 pKa = 3.89FNVSGRR32 pKa = 11.84VVVVFEE38 pKa = 3.84GQYY41 pKa = 10.21RR42 pKa = 11.84DD43 pKa = 3.06SFLEE47 pKa = 3.81LRR49 pKa = 11.84ARR51 pKa = 11.84TANSRR56 pKa = 11.84YY57 pKa = 9.52FLGAEE62 pKa = 4.28STRR65 pKa = 11.84QFPSLSDD72 pKa = 3.11STNRR76 pKa = 11.84VISEE80 pKa = 4.02SAGYY84 pKa = 8.1EE85 pKa = 3.8LKK87 pKa = 11.06VRR89 pKa = 11.84MKK91 pKa = 10.57VAAKK95 pKa = 10.12PIGEE99 pKa = 4.42CWCVCAQSTNWGCRR113 pKa = 11.84FRR115 pKa = 11.84LFWPGYY121 pKa = 8.4GASPPPRR128 pKa = 11.84HH129 pKa = 6.36GSPCPCSSPLSEE141 pKa = 4.06RR142 pKa = 11.84NRR144 pKa = 11.84RR145 pKa = 11.84LLLSSNSAAAILQRR159 pKa = 11.84QRR161 pKa = 11.84SKK163 pKa = 10.91GRR165 pKa = 11.84EE166 pKa = 3.61AGRR169 pKa = 11.84EE170 pKa = 3.88KK171 pKa = 10.73RR172 pKa = 11.84GGQLKK177 pKa = 9.45TYY179 pKa = 10.03SRR181 pKa = 11.84PKK183 pKa = 9.21PSYY186 pKa = 9.65ARR188 pKa = 11.84RR189 pKa = 11.84WQQSGDD195 pKa = 3.98PLDD198 pKa = 3.82QAAGSAPVRR207 pKa = 11.84PLLRR211 pKa = 11.84NPPPVTPAAGPTLKK225 pKa = 10.03GTGLGRR231 pKa = 11.84VLYY234 pKa = 10.64SGGLPFPLSKK244 pKa = 10.85ASAGRR249 pKa = 11.84GRR251 pKa = 11.84FLRR254 pKa = 11.84RR255 pKa = 11.84CLATSGFGQHH265 pKa = 6.42AVSEE269 pKa = 4.66CVCVSVCVCACVCVGHH285 pKa = 5.7TQSTVTRR292 pKa = 11.84AHH294 pKa = 6.85LAWSMPGNGKK304 pKa = 10.03RR305 pKa = 11.84GSRR308 pKa = 11.84QAA310 pKa = 3.44

Molecular weight: 33.79 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

18387

0

18387

7683767

10

7049

417.9

46.97

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

6.144 ± 0.016

2.215 ± 0.015

4.726 ± 0.015

7.526 ± 0.029

3.813 ± 0.015

6.321 ± 0.029

2.557 ± 0.009

4.972 ± 0.017

6.641 ± 0.026

9.65 ± 0.024

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

2.276 ± 0.008

4.129 ± 0.016

5.538 ± 0.024

4.705 ± 0.018

5.615 ± 0.022

8.257 ± 0.023

5.216 ± 0.014

5.709 ± 0.015

1.251 ± 0.007

2.724 ± 0.012
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski