Proteome-pI 2.0 - Proteome Isoelectric Point Database

Agaricus bisporus endornavirus 1

Taxonomy: Viruses; Riboviria; Orthornavirae; Kitrinoviricota; Alsuviricetes; Martellivirales; Endornaviridae; Alphaendornavirus; Agaricus bisporus alphaendornavirus 1

Average proteome isoelectric point is 5.97

Get precalculated fractions of proteins

Acidic

pI < 6.8

6.8-7.4

pI > 7.4

Basic

All

Virtual 2D-PAGE plot for 1 proteins (isoelectric point calculated using IPC2_protein)

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* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions

Protein with the lowest isoelectric point:

>tr|A0A1Q1M959|A0A1Q1M959_9VIRU Replicase OS=Agaricus bisporus endornavirus 1 OX=1945738 PE=4 SV=1

MM1 pKa = 7.35NSLAKK6 pKa = 10.46VEE8 pKa = 4.64TYY10 pKa = 7.96HH11 pKa = 4.87THH13 pKa = 4.86TRR15 pKa = 11.84GGGVPSKK22 pKa = 10.14IRR24 pKa = 11.84CYY26 pKa = 10.42TSFKK30 pKa = 9.66KK31 pKa = 9.18TLTAIQRR38 pKa = 11.84NKK40 pKa = 10.1HH41 pKa = 5.69CLGLQIDD48 pKa = 4.01EE49 pKa = 5.31DD50 pKa = 4.32FPKK53 pKa = 9.15TVKK56 pKa = 10.33MSDD59 pKa = 3.48PVDD62 pKa = 3.96EE63 pKa = 4.32YY64 pKa = 11.79ADD66 pKa = 4.61RR67 pKa = 11.84IKK69 pKa = 11.01LIVGATGVTEE79 pKa = 4.37VKK81 pKa = 10.04HH82 pKa = 6.45KK83 pKa = 9.43YY84 pKa = 8.67SHH86 pKa = 5.76MVGGAVYY93 pKa = 9.77FKK95 pKa = 10.74EE96 pKa = 3.91AMKK99 pKa = 10.52ISGLTRR105 pKa = 11.84EE106 pKa = 4.36EE107 pKa = 4.18LLSEE111 pKa = 4.15ILQTVRR117 pKa = 11.84SKK119 pKa = 10.01FVCLFEE125 pKa = 4.76CHH127 pKa = 6.46KK128 pKa = 10.68QDD130 pKa = 4.91DD131 pKa = 5.04PINMVMEE138 pKa = 5.02LGNEE142 pKa = 3.85ILNNLPEE149 pKa = 5.99DD150 pKa = 4.18DD151 pKa = 5.42DD152 pKa = 4.96EE153 pKa = 6.91NIDD156 pKa = 4.12SLCEE160 pKa = 4.1TISDD164 pKa = 4.62LYY166 pKa = 10.77LGEE169 pKa = 4.27YY170 pKa = 10.18NSYY173 pKa = 10.8DD174 pKa = 3.7YY175 pKa = 11.43EE176 pKa = 4.4EE177 pKa = 5.09EE178 pKa = 4.07EE179 pKa = 4.92HH180 pKa = 6.32EE181 pKa = 4.25HH182 pKa = 7.78CEE184 pKa = 5.04DD185 pKa = 4.35EE186 pKa = 5.43MEE188 pKa = 5.0LLDD191 pKa = 6.54DD192 pKa = 5.03IYY194 pKa = 11.55NDD196 pKa = 2.88VAAYY200 pKa = 10.01FEE202 pKa = 4.35VSDD205 pKa = 4.28MYY207 pKa = 10.5DD208 pKa = 3.15TPFTPEE214 pKa = 3.31QCLEE218 pKa = 4.0LLKK221 pKa = 11.01QFDD224 pKa = 4.23EE225 pKa = 5.61PITSSVDD232 pKa = 2.99ILKK235 pKa = 10.37LHH237 pKa = 6.82LNVKK241 pKa = 9.69HH242 pKa = 6.17LPKK245 pKa = 10.31LVNVAYY251 pKa = 10.32CANCEE256 pKa = 3.86MEE258 pKa = 5.96AILGHH263 pKa = 4.88NHH265 pKa = 6.45KK266 pKa = 10.66NVLTNCICLNCYY278 pKa = 10.11KK279 pKa = 10.46EE280 pKa = 4.35LTIKK284 pKa = 10.51PLGKK288 pKa = 9.7IGSTVPDD295 pKa = 3.89PMSLTEE301 pKa = 4.65YY302 pKa = 10.35LDD304 pKa = 3.76NGNSISGAFEE314 pKa = 4.76NIAQEE319 pKa = 3.62HH320 pKa = 6.48DD321 pKa = 3.58LRR323 pKa = 11.84VVVQALSRR331 pKa = 11.84LNAKK335 pKa = 10.2LITLHH340 pKa = 6.71EE341 pKa = 5.08PIDD344 pKa = 4.1NLTKK348 pKa = 10.55SYY350 pKa = 10.78LKK352 pKa = 10.6KK353 pKa = 10.39LAPEE357 pKa = 3.97LVFARR362 pKa = 11.84GKK364 pKa = 10.81GSLVGNTLLDD374 pKa = 3.64NLTIGLTANLHH385 pKa = 5.73NSGEE389 pKa = 4.41TTLLISEE396 pKa = 5.17HH397 pKa = 6.87PPPSPAYY404 pKa = 9.43INWNRR409 pKa = 11.84WPDD412 pKa = 3.33SNQNYY417 pKa = 9.07GFRR420 pKa = 11.84NTVVSIDD427 pKa = 3.89RR428 pKa = 11.84IVAGFKK434 pKa = 10.53LLSQLEE440 pKa = 4.31VDD442 pKa = 4.24CSVVFCLPTGIAGVTDD458 pKa = 3.92YY459 pKa = 9.43DD460 pKa = 3.71TTTNIRR466 pKa = 11.84FDD468 pKa = 3.72RR469 pKa = 11.84SNNSCLMTHH478 pKa = 6.81DD479 pKa = 3.72MRR481 pKa = 11.84TEE483 pKa = 3.51VHH485 pKa = 6.52YY486 pKa = 11.09INSTHH491 pKa = 7.36KK492 pKa = 10.23MLLFNANIMSINDD505 pKa = 3.51KK506 pKa = 10.72LFVISRR512 pKa = 11.84QTYY515 pKa = 10.11DD516 pKa = 3.53SICVVTVRR524 pKa = 11.84RR525 pKa = 11.84VVTFKK530 pKa = 11.0DD531 pKa = 3.03WTIYY535 pKa = 11.08NPDD538 pKa = 3.45LRR540 pKa = 11.84NTFTIPTITYY550 pKa = 9.17NSALGLVGAPIVVIKK565 pKa = 8.7TVKK568 pKa = 9.61LHH570 pKa = 6.91KK571 pKa = 10.29EE572 pKa = 3.76LLTTLITRR580 pKa = 11.84NLTGNVSAKK589 pKa = 10.11EE590 pKa = 3.65LAEE593 pKa = 4.16YY594 pKa = 11.0GLGFAHH600 pKa = 7.09SKK602 pKa = 11.01YY603 pKa = 11.05NLFDD607 pKa = 3.62KK608 pKa = 10.99SFSHH612 pKa = 6.8YY613 pKa = 10.5DD614 pKa = 3.14VSAQMIMDD622 pKa = 4.04HH623 pKa = 6.11VFISVLLCTRR633 pKa = 11.84ATNKK637 pKa = 9.48RR638 pKa = 11.84RR639 pKa = 11.84ALLNSATPDD648 pKa = 3.11LTGILNLIGYY658 pKa = 9.21NSLGYY663 pKa = 10.21LAATIKK669 pKa = 10.8KK670 pKa = 8.72MLDD673 pKa = 3.16KK674 pKa = 11.17NSTITALNDD683 pKa = 3.28FFTNNNSVLTEE694 pKa = 3.99YY695 pKa = 11.31ANDD698 pKa = 4.01PVWDD702 pKa = 4.79EE703 pKa = 4.23IEE705 pKa = 4.42SWTHH709 pKa = 4.43TATNEE714 pKa = 3.72NIQLITHH721 pKa = 6.23YY722 pKa = 7.3EE723 pKa = 4.17TPLGCCHH730 pKa = 6.66TDD732 pKa = 2.71IHH734 pKa = 7.07NDD736 pKa = 3.06SCGCCGLGNSTFRR749 pKa = 11.84CTHH752 pKa = 6.61CANTPAQLIEE762 pKa = 4.03TLNIVVEE769 pKa = 4.42EE770 pKa = 4.34KK771 pKa = 10.33IEE773 pKa = 4.03PSEE776 pKa = 3.95QVKK779 pKa = 8.69TRR781 pKa = 11.84NEE783 pKa = 4.02KK784 pKa = 9.99IFDD787 pKa = 3.92YY788 pKa = 11.2NGIPARR794 pKa = 11.84KK795 pKa = 8.8AVLPCVEE802 pKa = 4.94LSDD805 pKa = 4.39GSHH808 pKa = 5.75EE809 pKa = 4.34HH810 pKa = 5.93TCVVCNNRR818 pKa = 11.84YY819 pKa = 9.24KK820 pKa = 9.74HH821 pKa = 4.74THH823 pKa = 4.03NHH825 pKa = 5.64EE826 pKa = 4.43SSMHH830 pKa = 5.89PLFVGDD836 pKa = 5.12CPWCEE841 pKa = 4.0PEE843 pKa = 4.93LTTKK847 pKa = 10.86NKK849 pKa = 10.37GEE851 pKa = 4.38KK852 pKa = 8.9IDD854 pKa = 4.41YY855 pKa = 10.48LDD857 pKa = 4.27SNNNINKK864 pKa = 8.98PVKK867 pKa = 9.82TDD869 pKa = 3.24ANVPNKK875 pKa = 10.15PITPGPAKK883 pKa = 10.42LLNDD887 pKa = 3.52VPEE890 pKa = 4.34KK891 pKa = 10.29TEE893 pKa = 3.88RR894 pKa = 11.84TPEE897 pKa = 3.99STVPEE902 pKa = 4.57TPWGNSNRR910 pKa = 11.84LSVLYY915 pKa = 10.39SQLSQATSVHH925 pKa = 5.32FAEE928 pKa = 6.06LIYY931 pKa = 11.04SKK933 pKa = 10.73GARR936 pKa = 11.84FVNLYY941 pKa = 9.79TITNEE946 pKa = 3.94KK947 pKa = 10.06QSLILYY953 pKa = 8.97CPFGTHH959 pKa = 5.72VVTPQSFVVKK969 pKa = 9.78DD970 pKa = 3.56TMPVANSGLDD980 pKa = 3.24TCAYY984 pKa = 9.24DD985 pKa = 3.8ALNFFYY991 pKa = 10.59QNRR994 pKa = 11.84STIEE998 pKa = 3.83DD999 pKa = 4.11FKK1001 pKa = 11.58AVSKK1005 pKa = 9.96TDD1007 pKa = 3.64NFWSNDD1013 pKa = 3.4EE1014 pKa = 4.56IISVAEE1020 pKa = 3.98LKK1022 pKa = 10.63KK1023 pKa = 11.01LNVVVLSKK1031 pKa = 10.81QSGIIHH1037 pKa = 7.16KK1038 pKa = 8.46ATNSDD1043 pKa = 3.37EE1044 pKa = 4.31FAVIVHH1050 pKa = 6.64NDD1052 pKa = 3.28FLDD1055 pKa = 3.6KK1056 pKa = 10.9PGAHH1060 pKa = 5.68WTPAKK1065 pKa = 10.36VSQISNCTITPVWTLNADD1083 pKa = 4.0LEE1085 pKa = 4.74QYY1087 pKa = 11.65NKK1089 pKa = 9.26MSNMKK1094 pKa = 9.76YY1095 pKa = 9.76KK1096 pKa = 10.43KK1097 pKa = 9.99HH1098 pKa = 5.98YY1099 pKa = 10.64DD1100 pKa = 3.44LVKK1103 pKa = 10.75LDD1105 pKa = 3.87IEE1107 pKa = 4.22QLLTVNLEE1115 pKa = 3.8IVKK1118 pKa = 10.35ISTNTLEE1125 pKa = 4.77LLRR1128 pKa = 11.84HH1129 pKa = 6.09AKK1131 pKa = 10.02PNIVVDD1137 pKa = 4.05VKK1139 pKa = 10.72HH1140 pKa = 5.69GHH1142 pKa = 6.21EE1143 pKa = 4.21FLQTTSLSQDD1153 pKa = 2.93SMEE1156 pKa = 4.86LEE1158 pKa = 4.3TVEE1161 pKa = 4.74IPVKK1165 pKa = 10.66FSALMNLLNDD1175 pKa = 3.4SSKK1178 pKa = 9.94TVLEE1182 pKa = 4.01HH1183 pKa = 7.98DD1184 pKa = 3.65KK1185 pKa = 10.29LTRR1188 pKa = 11.84HH1189 pKa = 5.93YY1190 pKa = 11.12NVALTNTIDD1199 pKa = 3.6EE1200 pKa = 4.82LYY1202 pKa = 10.21EE1203 pKa = 4.1AEE1205 pKa = 3.83ITEE1208 pKa = 5.02AIRR1211 pKa = 11.84IFLKK1215 pKa = 10.82CKK1217 pKa = 10.25FGANITNYY1225 pKa = 10.6HH1226 pKa = 6.17KK1227 pKa = 10.49MRR1229 pKa = 11.84VIKK1232 pKa = 10.65RR1233 pKa = 11.84FDD1235 pKa = 3.57DD1236 pKa = 4.94LIEE1239 pKa = 4.6LEE1241 pKa = 4.68NLDD1244 pKa = 4.32LPKK1247 pKa = 10.86LKK1249 pKa = 10.89VGDD1252 pKa = 4.58IIHH1255 pKa = 7.23LSHH1258 pKa = 6.67QSNMIAVPILKK1269 pKa = 8.48TRR1271 pKa = 11.84HH1272 pKa = 4.59NTLVVKK1278 pKa = 9.63ITGVRR1283 pKa = 11.84VGVQLLFGITKK1294 pKa = 9.85EE1295 pKa = 4.46SAGSMIRR1302 pKa = 11.84RR1303 pKa = 11.84IFGLLRR1309 pKa = 11.84VPKK1312 pKa = 10.42LSNKK1316 pKa = 9.8LFEE1319 pKa = 4.21QLSNTEE1325 pKa = 4.18CVLAVPGAGKK1335 pKa = 8.73TYY1337 pKa = 10.59EE1338 pKa = 4.18ILNSYY1343 pKa = 9.32NAGDD1347 pKa = 5.01CIIAMTSHH1355 pKa = 6.42NKK1357 pKa = 9.54SSIYY1361 pKa = 10.14RR1362 pKa = 11.84RR1363 pKa = 11.84AKK1365 pKa = 9.58EE1366 pKa = 3.58MKK1368 pKa = 10.03KK1369 pKa = 9.77IVNVKK1374 pKa = 10.14SLEE1377 pKa = 4.1KK1378 pKa = 10.38FLSEE1382 pKa = 3.66GKK1384 pKa = 10.1KK1385 pKa = 10.6YY1386 pKa = 9.05KK1387 pKa = 9.43TVYY1390 pKa = 10.52LDD1392 pKa = 3.0EE1393 pKa = 4.67CTLVKK1398 pKa = 10.56PFDD1401 pKa = 3.89GVLVLTLCDD1410 pKa = 3.25KK1411 pKa = 10.58MYY1413 pKa = 10.82AYY1415 pKa = 10.49GDD1417 pKa = 3.55NNQIPFVDD1425 pKa = 4.44MSQSAGTRR1433 pKa = 11.84EE1434 pKa = 4.21VKK1436 pKa = 10.76NITDD1440 pKa = 3.39VVKK1443 pKa = 10.58PEE1445 pKa = 4.27KK1446 pKa = 10.43IEE1448 pKa = 4.1TKK1450 pKa = 10.24LLSRR1454 pKa = 11.84RR1455 pKa = 11.84FGPSLVSEE1463 pKa = 4.88LSPLIPGIMCHH1474 pKa = 6.6PSVEE1478 pKa = 4.25HH1479 pKa = 6.55DD1480 pKa = 3.13TDD1482 pKa = 3.24IRR1484 pKa = 11.84FANYY1488 pKa = 7.98EE1489 pKa = 4.07KK1490 pKa = 11.18NSIQVTAEE1498 pKa = 3.4IEE1500 pKa = 4.2NNVRR1504 pKa = 11.84NFKK1507 pKa = 10.64PNVVLVFFQAKK1518 pKa = 8.76KK1519 pKa = 10.67AFWLKK1524 pKa = 9.73RR1525 pKa = 11.84LHH1527 pKa = 6.64PIVVEE1532 pKa = 4.51TVHH1535 pKa = 6.8SYY1537 pKa = 10.38QGNEE1541 pKa = 3.61ADD1543 pKa = 3.46NVVVIQEE1550 pKa = 4.32PNEE1553 pKa = 4.19STFGICADD1561 pKa = 3.3KK1562 pKa = 10.85KK1563 pKa = 9.79YY1564 pKa = 10.75VISAASRR1571 pKa = 11.84AVKK1574 pKa = 10.08HH1575 pKa = 6.01LFWISIGMYY1584 pKa = 8.15QHH1586 pKa = 6.57NKK1588 pKa = 8.64GLSSRR1593 pKa = 11.84VYY1595 pKa = 8.99TLSPQRR1601 pKa = 11.84GGGIHH1606 pKa = 5.78KK1607 pKa = 8.22TFNAILDD1614 pKa = 4.38NITGVEE1620 pKa = 4.24MVSNTGTMIDD1630 pKa = 3.41ADD1632 pKa = 4.07KK1633 pKa = 11.24FNASKK1638 pKa = 10.52SAYY1641 pKa = 7.38EE1642 pKa = 3.98DD1643 pKa = 3.52KK1644 pKa = 11.45YY1645 pKa = 10.73GVKK1648 pKa = 10.46VSLANNSDD1656 pKa = 3.6GQSLEE1661 pKa = 3.78VRR1663 pKa = 11.84KK1664 pKa = 10.56VGILMVRR1671 pKa = 11.84FDD1673 pKa = 4.08IVNGVATTSYY1683 pKa = 11.37DD1684 pKa = 3.46RR1685 pKa = 11.84LNMVTSKK1692 pKa = 10.94DD1693 pKa = 3.61LSDD1696 pKa = 4.31LNEE1699 pKa = 4.12LLKK1702 pKa = 10.57PAVIQCDD1709 pKa = 3.44KK1710 pKa = 11.06FDD1712 pKa = 3.76TKK1714 pKa = 11.11FNTTIDD1720 pKa = 3.74SQQADD1725 pKa = 3.59IITFNMQLSALHH1737 pKa = 5.97SACASTQVTFYY1748 pKa = 11.18NDD1750 pKa = 3.11STEE1753 pKa = 3.78VSIICRR1759 pKa = 11.84TTHH1762 pKa = 4.78NKK1764 pKa = 9.1FRR1766 pKa = 11.84ISLSLNDD1773 pKa = 4.59DD1774 pKa = 3.65YY1775 pKa = 11.56CLKK1778 pKa = 8.82VQPMIIGRR1786 pKa = 11.84NFEE1789 pKa = 4.29THH1791 pKa = 4.22VHH1793 pKa = 5.73NVLTTLGYY1801 pKa = 9.65QDD1803 pKa = 4.29GSEE1806 pKa = 4.65EE1807 pKa = 4.57YY1808 pKa = 9.26PFSPAEE1814 pKa = 4.25PIKK1817 pKa = 8.76TTVINHH1823 pKa = 6.36TFNQIMNYY1831 pKa = 9.72LKK1833 pKa = 9.94TVVPDD1838 pKa = 4.11IIEE1841 pKa = 4.08QKK1843 pKa = 10.28MSDD1846 pKa = 3.17SKK1848 pKa = 11.58KK1849 pKa = 10.13FLNKK1853 pKa = 9.41ICEE1856 pKa = 4.22LTKK1859 pKa = 10.42EE1860 pKa = 4.05NEE1862 pKa = 3.88MVLLHH1867 pKa = 5.54NHH1869 pKa = 5.04EE1870 pKa = 4.44TGCYY1874 pKa = 7.9VVKK1877 pKa = 10.14TPINYY1882 pKa = 9.3KK1883 pKa = 10.34CVTPKK1888 pKa = 9.66CTYY1891 pKa = 8.18NTNAYY1896 pKa = 7.83NALMIFLNATSFKK1909 pKa = 9.24TSAMTILRR1917 pKa = 11.84LLTKK1921 pKa = 10.29SLIGSRR1927 pKa = 11.84TDD1929 pKa = 3.22NGIEE1933 pKa = 3.93GLMLPWHH1940 pKa = 5.2YY1941 pKa = 10.91HH1942 pKa = 4.6KK1943 pKa = 9.44THH1945 pKa = 5.76ATKK1948 pKa = 10.64AFKK1951 pKa = 10.42HH1952 pKa = 6.05YY1953 pKa = 9.77IDD1955 pKa = 4.8KK1956 pKa = 11.03SALLYY1961 pKa = 6.76MTSKK1965 pKa = 10.14IGEE1968 pKa = 4.05KK1969 pKa = 8.77RR1970 pKa = 11.84TIYY1973 pKa = 9.41VTEE1976 pKa = 3.89QNRR1979 pKa = 11.84DD1980 pKa = 3.02KK1981 pKa = 11.03IMNMVRR1987 pKa = 11.84DD1988 pKa = 3.65AGIDD1992 pKa = 3.44VNVNIHH1998 pKa = 6.48RR1999 pKa = 11.84FCPSLPLGVEE2009 pKa = 3.82IVGVLMVLSLDD2020 pKa = 4.09KK2021 pKa = 11.06SKK2023 pKa = 10.98QDD2025 pKa = 3.39RR2026 pKa = 11.84KK2027 pKa = 9.96IKK2029 pKa = 10.24IYY2031 pKa = 10.41GPHH2034 pKa = 6.67AGVLAANGFLNLQKK2048 pKa = 10.47VRR2050 pKa = 11.84DD2051 pKa = 3.84YY2052 pKa = 11.52HH2053 pKa = 6.41EE2054 pKa = 4.56LSTYY2058 pKa = 9.03EE2059 pKa = 3.79LHH2061 pKa = 7.48AVDD2064 pKa = 6.12DD2065 pKa = 4.46RR2066 pKa = 11.84MLSSVKK2072 pKa = 10.56NSVSEE2077 pKa = 4.03ALKK2080 pKa = 10.63KK2081 pKa = 10.64KK2082 pKa = 10.58QFDD2085 pKa = 3.59NTNTEE2090 pKa = 3.87KK2091 pKa = 11.09DD2092 pKa = 3.55DD2093 pKa = 4.33AFIKK2097 pKa = 10.76ALEE2100 pKa = 4.26TPNEE2104 pKa = 3.68INYY2107 pKa = 9.59AALYY2111 pKa = 9.89GYY2113 pKa = 10.33DD2114 pKa = 3.65YY2115 pKa = 11.86NLITNSNLLTDD2126 pKa = 4.28LSEE2129 pKa = 4.5FEE2131 pKa = 4.42TVKK2134 pKa = 11.02LITDD2138 pKa = 4.33LDD2140 pKa = 4.33SIEE2143 pKa = 4.12QCTEE2147 pKa = 3.86GSPTFVDD2154 pKa = 3.07NPMWQFTFKK2163 pKa = 10.4IPKK2166 pKa = 9.11ILNALIQTGADD2177 pKa = 3.49EE2178 pKa = 4.96NKK2180 pKa = 10.24LLSYY2184 pKa = 11.06DD2185 pKa = 3.63STFVGLGAVVGDD2197 pKa = 3.99IEE2199 pKa = 4.77QGVSKK2204 pKa = 10.55QLYY2207 pKa = 7.85SQLAGFVLRR2216 pKa = 11.84DD2217 pKa = 3.76QITLTVPRR2225 pKa = 11.84LNSSMIDD2232 pKa = 3.3GEE2234 pKa = 4.81VNVTSQEE2241 pKa = 3.77ITVSRR2246 pKa = 11.84KK2247 pKa = 9.03LFRR2250 pKa = 11.84DD2251 pKa = 3.21CGLRR2255 pKa = 11.84LLRR2258 pKa = 11.84EE2259 pKa = 3.86NHH2261 pKa = 7.29DD2262 pKa = 3.25IDD2264 pKa = 4.94SLLKK2268 pKa = 9.98HH2269 pKa = 6.14VRR2271 pKa = 11.84TKK2273 pKa = 10.09QHH2275 pKa = 4.67ATYY2278 pKa = 10.19YY2279 pKa = 9.87SDD2281 pKa = 3.01SGSYY2285 pKa = 9.38RR2286 pKa = 11.84QYY2288 pKa = 11.41KK2289 pKa = 6.34EE2290 pKa = 4.22TPGAAMDD2297 pKa = 4.2LCLAVYY2303 pKa = 10.39LRR2305 pKa = 11.84YY2306 pKa = 9.99NNKK2309 pKa = 8.16FTEE2312 pKa = 4.42LFDD2315 pKa = 4.28TIKK2318 pKa = 9.96WLQPEE2323 pKa = 4.45TVKK2326 pKa = 10.93QEE2328 pKa = 4.57GIFEE2332 pKa = 4.67LLLDD2336 pKa = 4.26NLGSSAKK2343 pKa = 10.33EE2344 pKa = 3.5MVLNVVSKK2352 pKa = 10.89LSGIAGMNLPQKK2364 pKa = 10.84DD2365 pKa = 4.26FIKK2368 pKa = 9.96TIWKK2372 pKa = 9.25VVRR2375 pKa = 11.84NMAFHH2380 pKa = 6.11QEE2382 pKa = 3.91DD2383 pKa = 4.38MFTEE2387 pKa = 4.63TMSVMNVEE2395 pKa = 4.29EE2396 pKa = 4.7RR2397 pKa = 11.84ISTRR2401 pKa = 11.84RR2402 pKa = 11.84LLMRR2406 pKa = 11.84GTKK2409 pKa = 9.64QILMTSGAASIDD2421 pKa = 3.31EE2422 pKa = 4.53GANKK2426 pKa = 8.26VTLQSKK2432 pKa = 9.26YY2433 pKa = 7.93LHH2435 pKa = 6.55KK2436 pKa = 10.69LFSNMSTLMQSVSARR2451 pKa = 11.84HH2452 pKa = 6.44DD2453 pKa = 3.58PVTLMKK2459 pKa = 10.86DD2460 pKa = 3.2FTKK2463 pKa = 10.45PKK2465 pKa = 9.87SICCICIGSFGDD2477 pKa = 3.56ITNHH2481 pKa = 5.58LQVANMAVHH2490 pKa = 6.61EE2491 pKa = 4.46GVKK2494 pKa = 10.51VSLIFPDD2501 pKa = 3.69SYY2503 pKa = 11.2LDD2505 pKa = 3.61QVRR2508 pKa = 11.84SIADD2512 pKa = 3.42SKK2514 pKa = 10.05VTLVPQRR2521 pKa = 11.84FSVDD2525 pKa = 3.05NHH2527 pKa = 5.8IKK2529 pKa = 10.55LLNEE2533 pKa = 3.76LRR2535 pKa = 11.84TDD2537 pKa = 3.45NLEE2540 pKa = 4.31VLMTAYY2546 pKa = 9.6TEE2548 pKa = 4.21EE2549 pKa = 4.51KK2550 pKa = 10.71GALLYY2555 pKa = 11.03NDD2557 pKa = 4.54FDD2559 pKa = 4.69YY2560 pKa = 11.32KK2561 pKa = 10.44ILKK2564 pKa = 9.13PDD2566 pKa = 3.9LVVGTCLTVQGPIIAKK2582 pKa = 9.79KK2583 pKa = 10.15FNANYY2588 pKa = 10.62LEE2590 pKa = 4.85LNALPWNLVRR2600 pKa = 11.84AEE2602 pKa = 4.06NKK2604 pKa = 10.31RR2605 pKa = 11.84FDD2607 pKa = 3.51SLKK2610 pKa = 8.65NVLYY2614 pKa = 10.27RR2615 pKa = 11.84GYY2617 pKa = 10.83RR2618 pKa = 11.84AMQLEE2623 pKa = 4.81TIIKK2627 pKa = 8.87QYY2629 pKa = 11.2AIAGLQNPTPQDD2641 pKa = 3.65IISEE2645 pKa = 4.46NYY2647 pKa = 8.94TSVNVIDD2654 pKa = 5.16PIFGLVAEE2662 pKa = 4.91KK2663 pKa = 10.59EE2664 pKa = 4.15NHH2666 pKa = 5.82SVVGFLPFKK2675 pKa = 8.86YY2676 pKa = 8.87TNSKK2680 pKa = 9.23TILTTKK2686 pKa = 9.58TCVLTLGSMKK2696 pKa = 10.18TKK2698 pKa = 10.01QHH2700 pKa = 5.52ANKK2703 pKa = 9.83LISVAKK2709 pKa = 9.85KK2710 pKa = 8.92LLSFGEE2716 pKa = 4.24HH2717 pKa = 3.91VTIVEE2722 pKa = 4.3GGVKK2726 pKa = 10.12FNKK2729 pKa = 9.92EE2730 pKa = 3.82FIDD2733 pKa = 5.09RR2734 pKa = 11.84SDD2736 pKa = 3.31KK2737 pKa = 11.09LQIVSNVDD2745 pKa = 3.1YY2746 pKa = 10.37TSQLVHH2752 pKa = 6.75CKK2754 pKa = 10.41LMLHH2758 pKa = 6.5HH2759 pKa = 6.95CGSGTTHH2766 pKa = 6.48TAMLAGLPQILLPVDD2781 pKa = 4.39FDD2783 pKa = 3.66QPQWAGALNKK2793 pKa = 9.99KK2794 pKa = 10.37GYY2796 pKa = 9.98GVYY2799 pKa = 10.49ADD2801 pKa = 4.41EE2802 pKa = 4.85LLNMEE2807 pKa = 5.4LDD2809 pKa = 5.51DD2810 pKa = 3.83FTHH2813 pKa = 6.67WFNVTLEE2820 pKa = 4.1KK2821 pKa = 10.38TKK2823 pKa = 11.02NDD2825 pKa = 3.42SNKK2828 pKa = 9.62MIRR2831 pKa = 11.84HH2832 pKa = 5.36TATNIAHH2839 pKa = 6.94ALKK2842 pKa = 9.43LTDD2845 pKa = 3.53NAITDD2850 pKa = 4.25SVTLTTDD2857 pKa = 2.72ITIEE2861 pKa = 3.88EE2862 pKa = 4.05EE2863 pKa = 4.41AIIRR2867 pKa = 11.84DD2868 pKa = 4.05NIHH2871 pKa = 6.17KK2872 pKa = 10.69CNLHH2876 pKa = 5.28KK2877 pKa = 10.72CKK2879 pKa = 9.83PLEE2882 pKa = 4.2TMSVLINTCCGEE2894 pKa = 4.18RR2895 pKa = 11.84KK2896 pKa = 8.25RR2897 pKa = 11.84HH2898 pKa = 4.98CVIGEE2903 pKa = 4.06TEE2905 pKa = 3.72EE2906 pKa = 4.69CYY2908 pKa = 10.51IIVNSTHH2915 pKa = 6.24YY2916 pKa = 9.58PDD2918 pKa = 6.03HH2919 pKa = 7.13RR2920 pKa = 11.84IGWNRR2925 pKa = 11.84KK2926 pKa = 5.56QHH2928 pKa = 6.28IAIQPIMPIPVLRR2941 pKa = 11.84GHH2943 pKa = 6.07YY2944 pKa = 9.82EE2945 pKa = 3.7IATLGYY2951 pKa = 8.82HH2952 pKa = 5.3AHH2954 pKa = 6.51GMCEE2958 pKa = 4.44ANSEE2962 pKa = 4.48SPPNFYY2968 pKa = 10.34IKK2970 pKa = 10.15PNQVSEE2976 pKa = 4.34FNKK2979 pKa = 10.7SIDD2982 pKa = 3.49WIDD2985 pKa = 3.9LVRR2988 pKa = 11.84LHH2990 pKa = 6.57NGRR2993 pKa = 11.84WSNRR2997 pKa = 11.84GVFGIEE3003 pKa = 3.78PRR3005 pKa = 11.84TGICNCCHH3013 pKa = 6.83RR3014 pKa = 11.84SMWLLRR3020 pKa = 11.84SQNEE3024 pKa = 4.15KK3025 pKa = 10.82LCTSCHH3031 pKa = 5.46IQINWPQFTFTDD3043 pKa = 3.89SVSTTKK3049 pKa = 10.39TDD3051 pKa = 3.1NFKK3054 pKa = 10.62AKK3056 pKa = 10.03SRR3058 pKa = 11.84AGHH3061 pKa = 6.92IIFEE3065 pKa = 4.27LSKK3068 pKa = 10.55LQEE3071 pKa = 4.15SHH3073 pKa = 6.98VLLDD3077 pKa = 3.59PKK3079 pKa = 11.07GNSNCVPNCLRR3090 pKa = 11.84AVAKK3094 pKa = 10.63YY3095 pKa = 7.16STKK3098 pKa = 10.3VSSTINNAFIDD3109 pKa = 3.82FEE3111 pKa = 4.72IGEE3114 pKa = 4.27FTSIEE3119 pKa = 4.34KK3120 pKa = 10.04IIQICRR3126 pKa = 11.84FMRR3129 pKa = 11.84VDD3131 pKa = 3.19IQVDD3135 pKa = 3.58HH3136 pKa = 7.28PNVKK3140 pKa = 9.12TGGRR3144 pKa = 11.84LLHH3147 pKa = 6.34NLEE3150 pKa = 4.07FDD3152 pKa = 3.5KK3153 pKa = 11.08TPKK3156 pKa = 10.21LRR3158 pKa = 11.84LLITGEE3164 pKa = 4.13RR3165 pKa = 11.84EE3166 pKa = 3.92QHH3168 pKa = 5.56CTLTAAIKK3176 pKa = 10.36IPAAQKK3182 pKa = 10.61SITLIEE3188 pKa = 4.34TEE3190 pKa = 4.46NPCDD3194 pKa = 4.84DD3195 pKa = 4.21MNSLITTDD3203 pKa = 5.2LIDD3206 pKa = 4.27NADD3209 pKa = 3.34MDD3211 pKa = 4.39FNQILKK3217 pKa = 9.46TNLKK3221 pKa = 8.02TFRR3224 pKa = 11.84STKK3227 pKa = 8.02YY3228 pKa = 8.22TDD3230 pKa = 4.14VIAKK3234 pKa = 6.67TTDD3237 pKa = 2.88GKK3239 pKa = 11.34LNIYY3243 pKa = 9.05GRR3245 pKa = 11.84RR3246 pKa = 11.84NLLVEE3251 pKa = 3.99ANIVFRR3257 pKa = 11.84KK3258 pKa = 9.55FKK3260 pKa = 9.6SHH3262 pKa = 5.61EE3263 pKa = 4.19MYY3265 pKa = 10.58FGEE3268 pKa = 4.95LPEE3271 pKa = 4.26SFNRR3275 pKa = 11.84FEE3277 pKa = 5.64DD3278 pKa = 4.79RR3279 pKa = 11.84ILCVPTRR3286 pKa = 11.84TGNVIGLVTRR3296 pKa = 11.84LNNTEE3301 pKa = 3.78KK3302 pKa = 10.77QLIVLTGQRR3311 pKa = 11.84PLPVVNYY3318 pKa = 10.18VIDD3321 pKa = 4.1ASVSITKK3328 pKa = 9.62VKK3330 pKa = 10.06KK3331 pKa = 9.67HH3332 pKa = 6.04KK3333 pKa = 10.57KK3334 pKa = 9.31LIKK3337 pKa = 10.17NDD3339 pKa = 3.59TVTVGAFNEE3348 pKa = 4.07KK3349 pKa = 9.98SRR3351 pKa = 11.84RR3352 pKa = 11.84EE3353 pKa = 3.89LSTIYY3358 pKa = 10.24PGISVNRR3365 pKa = 11.84NCQKK3369 pKa = 10.65VVISSLDD3376 pKa = 3.42TRR3378 pKa = 11.84NHH3380 pKa = 5.86HH3381 pKa = 7.25LYY3383 pKa = 10.75SEE3385 pKa = 4.29WNEE3388 pKa = 3.56MHH3390 pKa = 6.68TLLNRR3395 pKa = 11.84NTMGEE3400 pKa = 4.26TLIEE3404 pKa = 4.34LYY3406 pKa = 10.87GKK3408 pKa = 10.47LDD3410 pKa = 3.65GATVPTLVDD3419 pKa = 3.65SNLTQSICEE3428 pKa = 3.94QFSRR3432 pKa = 11.84TTRR3435 pKa = 11.84DD3436 pKa = 3.06QIFRR3440 pKa = 11.84FGWDD3444 pKa = 2.99QKK3446 pKa = 10.02PTVEE3450 pKa = 3.47TWTRR3454 pKa = 11.84DD3455 pKa = 3.14KK3456 pKa = 10.66PTGLFLEE3463 pKa = 4.68EE3464 pKa = 4.1QGFTSPEE3471 pKa = 3.67NEE3473 pKa = 4.14RR3474 pKa = 11.84YY3475 pKa = 9.95VLDD3478 pKa = 3.64YY3479 pKa = 11.13EE3480 pKa = 4.26QFKK3483 pKa = 10.92DD3484 pKa = 3.52ISEE3487 pKa = 4.59LNDD3490 pKa = 3.4TEE3492 pKa = 4.54TMNKK3496 pKa = 10.14LISCDD3501 pKa = 3.74LIGYY3505 pKa = 9.73ISLKK3509 pKa = 10.39NCVKK3513 pKa = 9.92YY3514 pKa = 10.16FEE3516 pKa = 5.41IIKK3519 pKa = 8.76STEE3522 pKa = 4.31DD3523 pKa = 2.79IVAFTGVDD3531 pKa = 3.24KK3532 pKa = 11.77NEE3534 pKa = 4.37LNRR3537 pKa = 11.84EE3538 pKa = 4.18LIDD3541 pKa = 3.7YY3542 pKa = 10.65DD3543 pKa = 3.99EE3544 pKa = 5.53ASLTVTCGPIWKK3556 pKa = 9.84GGLPEE3561 pKa = 4.09ITTMDD3566 pKa = 3.71SLNRR3570 pKa = 11.84TVFVRR3575 pKa = 11.84PEE3577 pKa = 4.45DD3578 pKa = 3.42IKK3580 pKa = 11.18EE3581 pKa = 4.39SNGEE3585 pKa = 3.84LTLVWFRR3592 pKa = 11.84SNCLILTTFVWKK3604 pKa = 10.48KK3605 pKa = 9.22KK3606 pKa = 9.46VRR3608 pKa = 11.84GGSYY3612 pKa = 9.88GQKK3615 pKa = 9.87QDD3617 pKa = 4.89LEE3619 pKa = 4.24DD3620 pKa = 3.63RR3621 pKa = 11.84KK3622 pKa = 10.93QNIDD3626 pKa = 3.11SDD3628 pKa = 4.19NNKK3631 pKa = 10.21LYY3633 pKa = 10.14WFNEE3637 pKa = 4.27EE3638 pKa = 3.46IEE3640 pKa = 4.25EE3641 pKa = 4.13RR3642 pKa = 11.84LEE3644 pKa = 3.99HH3645 pKa = 6.84RR3646 pKa = 11.84GAEE3649 pKa = 3.93SWIDD3653 pKa = 3.39KK3654 pKa = 10.47GSKK3657 pKa = 9.4PKK3659 pKa = 9.08NTQLPALAANEE3670 pKa = 4.3VEE3672 pKa = 5.32LDD3674 pKa = 3.7ALCSVFNDD3682 pKa = 3.32GMRR3685 pKa = 11.84GYY3687 pKa = 10.55DD3688 pKa = 2.8GKK3690 pKa = 9.17TFVASEE3696 pKa = 3.92PANKK3700 pKa = 9.44KK3701 pKa = 9.88FLMFTEE3707 pKa = 5.01PDD3709 pKa = 3.37TPNFVCHH3716 pKa = 5.43EE3717 pKa = 4.23TGEE3720 pKa = 4.37GPEE3723 pKa = 4.19IGTEE3727 pKa = 4.02VMDD3730 pKa = 6.0IIDD3733 pKa = 4.77DD3734 pKa = 3.72VDD3736 pKa = 4.14LADD3739 pKa = 3.89HH3740 pKa = 5.72VTRR3743 pKa = 11.84LAPKK3747 pKa = 8.26TGIIKK3752 pKa = 9.61SHH3754 pKa = 5.77EE3755 pKa = 3.99VPGRR3759 pKa = 11.84IVTNTKK3765 pKa = 7.01TTMVKK3770 pKa = 9.86YY3771 pKa = 10.36PEE3773 pKa = 4.04MSKK3776 pKa = 10.63PVITKK3781 pKa = 10.01GVYY3784 pKa = 6.69QTFNAVSSRR3793 pKa = 11.84LHH3795 pKa = 6.23SVVKK3799 pKa = 10.0YY3800 pKa = 9.77RR3801 pKa = 11.84KK3802 pKa = 8.91HH3803 pKa = 7.3KK3804 pKa = 9.22MDD3806 pKa = 3.27VVSEE3810 pKa = 4.09FDD3812 pKa = 3.14RR3813 pKa = 11.84CANCYY3818 pKa = 8.19FVPNYY3823 pKa = 9.63QHH3825 pKa = 6.93VLDD3828 pKa = 4.68EE3829 pKa = 4.9FKK3831 pKa = 11.07NDD3833 pKa = 4.29PITYY3837 pKa = 9.07NVNNIVDD3844 pKa = 3.54WVNRR3848 pKa = 11.84RR3849 pKa = 11.84KK3850 pKa = 10.34NSSVVAAEE3858 pKa = 4.98LIEE3861 pKa = 4.34LMQTGWFNHH3870 pKa = 7.06PINSVKK3876 pKa = 10.11VHH3878 pKa = 6.3SKK3880 pKa = 11.03LEE3882 pKa = 4.1SLLKK3886 pKa = 10.19EE3887 pKa = 4.29DD3888 pKa = 4.72EE3889 pKa = 4.0IGYY3892 pKa = 10.15QYY3894 pKa = 10.88GQQKK3898 pKa = 9.4IRR3900 pKa = 11.84IIVHH3904 pKa = 3.57QTYY3907 pKa = 10.45AICAIFADD3915 pKa = 3.84IFLQAKK3921 pKa = 9.32EE3922 pKa = 4.18RR3923 pKa = 11.84FKK3925 pKa = 11.19QLLGEE3930 pKa = 4.2KK3931 pKa = 9.77CVYY3934 pKa = 11.1ADD3936 pKa = 3.56GFTLEE3941 pKa = 4.02EE3942 pKa = 3.69LAARR3946 pKa = 11.84MRR3948 pKa = 11.84LIKK3951 pKa = 9.92SDD3953 pKa = 3.15KK3954 pKa = 9.23PLWVFEE3960 pKa = 4.44RR3961 pKa = 11.84DD3962 pKa = 3.24FTKK3965 pKa = 10.34QDD3967 pKa = 3.16RR3968 pKa = 11.84QTDD3971 pKa = 3.3EE3972 pKa = 4.91DD3973 pKa = 4.77LINFEE3978 pKa = 4.25MYY3980 pKa = 10.13VYY3982 pKa = 10.32KK3983 pKa = 10.51QLGVHH3988 pKa = 7.14DD3989 pKa = 4.87DD3990 pKa = 4.3VISFWRR3996 pKa = 11.84KK3997 pKa = 5.64THH3999 pKa = 6.19EE4000 pKa = 3.37NWFYY4004 pKa = 11.37KK4005 pKa = 9.92GTDD4008 pKa = 3.44LSGSLSWMRR4017 pKa = 11.84LTGQCTTALGNAITNMVVNSRR4038 pKa = 11.84TYY4040 pKa = 10.44QEE4042 pKa = 4.14YY4043 pKa = 9.5EE4044 pKa = 3.87QNIKK4048 pKa = 10.39IMLLLGDD4055 pKa = 4.8DD4056 pKa = 3.76NSMISDD4062 pKa = 4.07CEE4064 pKa = 4.27INVHH4068 pKa = 5.55NSRR4071 pKa = 11.84KK4072 pKa = 9.51ISRR4075 pKa = 11.84DD4076 pKa = 3.48YY4077 pKa = 11.78YY4078 pKa = 11.29NMEE4081 pKa = 4.5SKK4083 pKa = 10.77DD4084 pKa = 3.47FCKK4087 pKa = 10.36KK4088 pKa = 8.62HH4089 pKa = 5.21TGIFLRR4095 pKa = 11.84MILHH4099 pKa = 5.22QQQDD4103 pKa = 3.88GSMSVCPDD4111 pKa = 3.53FLRR4114 pKa = 11.84LRR4116 pKa = 11.84RR4117 pKa = 11.84RR4118 pKa = 11.84YY4119 pKa = 8.62EE4120 pKa = 3.81VTNGVHH4126 pKa = 6.98KK4127 pKa = 10.77MGDD4130 pKa = 3.52EE4131 pKa = 3.98EE4132 pKa = 4.61LKK4134 pKa = 11.09LRR4136 pKa = 11.84GLSYY4140 pKa = 11.19LYY4142 pKa = 9.89MLGRR4146 pKa = 11.84NKK4148 pKa = 8.9VTEE4151 pKa = 4.1EE4152 pKa = 3.93AVTSLGYY4159 pKa = 10.37NDD4161 pKa = 4.85EE4162 pKa = 4.76LLPTYY4167 pKa = 11.01YY4168 pKa = 10.66NFEE4171 pKa = 4.18EE4172 pKa = 4.42AVMAVATNNGMTNDD4186 pKa = 3.46AARR4189 pKa = 11.84NEE4191 pKa = 4.11FNLLIDD4197 pKa = 4.01MIKK4200 pKa = 10.67ANKK4203 pKa = 10.01SYY4205 pKa = 11.25DD4206 pKa = 3.02VDD4208 pKa = 4.09YY4209 pKa = 11.29VVTSSQIRR4217 pKa = 3.39

Molecular weight: 478.17 kDa
Isoelectric point according different methods:

Protein with the highest isoelectric point:

>tr|A0A1Q1M959|A0A1Q1M959_9VIRU Replicase OS=Agaricus bisporus endornavirus 1 OX=1945738 PE=4 SV=1

MM1 pKa = 7.35NSLAKK6 pKa = 10.46VEE8 pKa = 4.64TYY10 pKa = 7.96HH11 pKa = 4.87THH13 pKa = 4.86TRR15 pKa = 11.84GGGVPSKK22 pKa = 10.14IRR24 pKa = 11.84CYY26 pKa = 10.42TSFKK30 pKa = 9.66KK31 pKa = 9.18TLTAIQRR38 pKa = 11.84NKK40 pKa = 10.1HH41 pKa = 5.69CLGLQIDD48 pKa = 4.01EE49 pKa = 5.31DD50 pKa = 4.32FPKK53 pKa = 9.15TVKK56 pKa = 10.33MSDD59 pKa = 3.48PVDD62 pKa = 3.96EE63 pKa = 4.32YY64 pKa = 11.79ADD66 pKa = 4.61RR67 pKa = 11.84IKK69 pKa = 11.01LIVGATGVTEE79 pKa = 4.37VKK81 pKa = 10.04HH82 pKa = 6.45KK83 pKa = 9.43YY84 pKa = 8.67SHH86 pKa = 5.76MVGGAVYY93 pKa = 9.77FKK95 pKa = 10.74EE96 pKa = 3.91AMKK99 pKa = 10.52ISGLTRR105 pKa = 11.84EE106 pKa = 4.36EE107 pKa = 4.18LLSEE111 pKa = 4.15ILQTVRR117 pKa = 11.84SKK119 pKa = 10.01FVCLFEE125 pKa = 4.76CHH127 pKa = 6.46KK128 pKa = 10.68QDD130 pKa = 4.91DD131 pKa = 5.04PINMVMEE138 pKa = 5.02LGNEE142 pKa = 3.85ILNNLPEE149 pKa = 5.99DD150 pKa = 4.18DD151 pKa = 5.42DD152 pKa = 4.96EE153 pKa = 6.91NIDD156 pKa = 4.12SLCEE160 pKa = 4.1TISDD164 pKa = 4.62LYY166 pKa = 10.77LGEE169 pKa = 4.27YY170 pKa = 10.18NSYY173 pKa = 10.8DD174 pKa = 3.7YY175 pKa = 11.43EE176 pKa = 4.4EE177 pKa = 5.09EE178 pKa = 4.07EE179 pKa = 4.92HH180 pKa = 6.32EE181 pKa = 4.25HH182 pKa = 7.78CEE184 pKa = 5.04DD185 pKa = 4.35EE186 pKa = 5.43MEE188 pKa = 5.0LLDD191 pKa = 6.54DD192 pKa = 5.03IYY194 pKa = 11.55NDD196 pKa = 2.88VAAYY200 pKa = 10.01FEE202 pKa = 4.35VSDD205 pKa = 4.28MYY207 pKa = 10.5DD208 pKa = 3.15TPFTPEE214 pKa = 3.31QCLEE218 pKa = 4.0LLKK221 pKa = 11.01QFDD224 pKa = 4.23EE225 pKa = 5.61PITSSVDD232 pKa = 2.99ILKK235 pKa = 10.37LHH237 pKa = 6.82LNVKK241 pKa = 9.69HH242 pKa = 6.17LPKK245 pKa = 10.31LVNVAYY251 pKa = 10.32CANCEE256 pKa = 3.86MEE258 pKa = 5.96AILGHH263 pKa = 4.88NHH265 pKa = 6.45KK266 pKa = 10.66NVLTNCICLNCYY278 pKa = 10.11KK279 pKa = 10.46EE280 pKa = 4.35LTIKK284 pKa = 10.51PLGKK288 pKa = 9.7IGSTVPDD295 pKa = 3.89PMSLTEE301 pKa = 4.65YY302 pKa = 10.35LDD304 pKa = 3.76NGNSISGAFEE314 pKa = 4.76NIAQEE319 pKa = 3.62HH320 pKa = 6.48DD321 pKa = 3.58LRR323 pKa = 11.84VVVQALSRR331 pKa = 11.84LNAKK335 pKa = 10.2LITLHH340 pKa = 6.71EE341 pKa = 5.08PIDD344 pKa = 4.1NLTKK348 pKa = 10.55SYY350 pKa = 10.78LKK352 pKa = 10.6KK353 pKa = 10.39LAPEE357 pKa = 3.97LVFARR362 pKa = 11.84GKK364 pKa = 10.81GSLVGNTLLDD374 pKa = 3.64NLTIGLTANLHH385 pKa = 5.73NSGEE389 pKa = 4.41TTLLISEE396 pKa = 5.17HH397 pKa = 6.87PPPSPAYY404 pKa = 9.43INWNRR409 pKa = 11.84WPDD412 pKa = 3.33SNQNYY417 pKa = 9.07GFRR420 pKa = 11.84NTVVSIDD427 pKa = 3.89RR428 pKa = 11.84IVAGFKK434 pKa = 10.53LLSQLEE440 pKa = 4.31VDD442 pKa = 4.24CSVVFCLPTGIAGVTDD458 pKa = 3.92YY459 pKa = 9.43DD460 pKa = 3.71TTTNIRR466 pKa = 11.84FDD468 pKa = 3.72RR469 pKa = 11.84SNNSCLMTHH478 pKa = 6.81DD479 pKa = 3.72MRR481 pKa = 11.84TEE483 pKa = 3.51VHH485 pKa = 6.52YY486 pKa = 11.09INSTHH491 pKa = 7.36KK492 pKa = 10.23MLLFNANIMSINDD505 pKa = 3.51KK506 pKa = 10.72LFVISRR512 pKa = 11.84QTYY515 pKa = 10.11DD516 pKa = 3.53SICVVTVRR524 pKa = 11.84RR525 pKa = 11.84VVTFKK530 pKa = 11.0DD531 pKa = 3.03WTIYY535 pKa = 11.08NPDD538 pKa = 3.45LRR540 pKa = 11.84NTFTIPTITYY550 pKa = 9.17NSALGLVGAPIVVIKK565 pKa = 8.7TVKK568 pKa = 9.61LHH570 pKa = 6.91KK571 pKa = 10.29EE572 pKa = 3.76LLTTLITRR580 pKa = 11.84NLTGNVSAKK589 pKa = 10.11EE590 pKa = 3.65LAEE593 pKa = 4.16YY594 pKa = 11.0GLGFAHH600 pKa = 7.09SKK602 pKa = 11.01YY603 pKa = 11.05NLFDD607 pKa = 3.62KK608 pKa = 10.99SFSHH612 pKa = 6.8YY613 pKa = 10.5DD614 pKa = 3.14VSAQMIMDD622 pKa = 4.04HH623 pKa = 6.11VFISVLLCTRR633 pKa = 11.84ATNKK637 pKa = 9.48RR638 pKa = 11.84RR639 pKa = 11.84ALLNSATPDD648 pKa = 3.11LTGILNLIGYY658 pKa = 9.21NSLGYY663 pKa = 10.21LAATIKK669 pKa = 10.8KK670 pKa = 8.72MLDD673 pKa = 3.16KK674 pKa = 11.17NSTITALNDD683 pKa = 3.28FFTNNNSVLTEE694 pKa = 3.99YY695 pKa = 11.31ANDD698 pKa = 4.01PVWDD702 pKa = 4.79EE703 pKa = 4.23IEE705 pKa = 4.42SWTHH709 pKa = 4.43TATNEE714 pKa = 3.72NIQLITHH721 pKa = 6.23YY722 pKa = 7.3EE723 pKa = 4.17TPLGCCHH730 pKa = 6.66TDD732 pKa = 2.71IHH734 pKa = 7.07NDD736 pKa = 3.06SCGCCGLGNSTFRR749 pKa = 11.84CTHH752 pKa = 6.61CANTPAQLIEE762 pKa = 4.03TLNIVVEE769 pKa = 4.42EE770 pKa = 4.34KK771 pKa = 10.33IEE773 pKa = 4.03PSEE776 pKa = 3.95QVKK779 pKa = 8.69TRR781 pKa = 11.84NEE783 pKa = 4.02KK784 pKa = 9.99IFDD787 pKa = 3.92YY788 pKa = 11.2NGIPARR794 pKa = 11.84KK795 pKa = 8.8AVLPCVEE802 pKa = 4.94LSDD805 pKa = 4.39GSHH808 pKa = 5.75EE809 pKa = 4.34HH810 pKa = 5.93TCVVCNNRR818 pKa = 11.84YY819 pKa = 9.24KK820 pKa = 9.74HH821 pKa = 4.74THH823 pKa = 4.03NHH825 pKa = 5.64EE826 pKa = 4.43SSMHH830 pKa = 5.89PLFVGDD836 pKa = 5.12CPWCEE841 pKa = 4.0PEE843 pKa = 4.93LTTKK847 pKa = 10.86NKK849 pKa = 10.37GEE851 pKa = 4.38KK852 pKa = 8.9IDD854 pKa = 4.41YY855 pKa = 10.48LDD857 pKa = 4.27SNNNINKK864 pKa = 8.98PVKK867 pKa = 9.82TDD869 pKa = 3.24ANVPNKK875 pKa = 10.15PITPGPAKK883 pKa = 10.42LLNDD887 pKa = 3.52VPEE890 pKa = 4.34KK891 pKa = 10.29TEE893 pKa = 3.88RR894 pKa = 11.84TPEE897 pKa = 3.99STVPEE902 pKa = 4.57TPWGNSNRR910 pKa = 11.84LSVLYY915 pKa = 10.39SQLSQATSVHH925 pKa = 5.32FAEE928 pKa = 6.06LIYY931 pKa = 11.04SKK933 pKa = 10.73GARR936 pKa = 11.84FVNLYY941 pKa = 9.79TITNEE946 pKa = 3.94KK947 pKa = 10.06QSLILYY953 pKa = 8.97CPFGTHH959 pKa = 5.72VVTPQSFVVKK969 pKa = 9.78DD970 pKa = 3.56TMPVANSGLDD980 pKa = 3.24TCAYY984 pKa = 9.24DD985 pKa = 3.8ALNFFYY991 pKa = 10.59QNRR994 pKa = 11.84STIEE998 pKa = 3.83DD999 pKa = 4.11FKK1001 pKa = 11.58AVSKK1005 pKa = 9.96TDD1007 pKa = 3.64NFWSNDD1013 pKa = 3.4EE1014 pKa = 4.56IISVAEE1020 pKa = 3.98LKK1022 pKa = 10.63KK1023 pKa = 11.01LNVVVLSKK1031 pKa = 10.81QSGIIHH1037 pKa = 7.16KK1038 pKa = 8.46ATNSDD1043 pKa = 3.37EE1044 pKa = 4.31FAVIVHH1050 pKa = 6.64NDD1052 pKa = 3.28FLDD1055 pKa = 3.6KK1056 pKa = 10.9PGAHH1060 pKa = 5.68WTPAKK1065 pKa = 10.36VSQISNCTITPVWTLNADD1083 pKa = 4.0LEE1085 pKa = 4.74QYY1087 pKa = 11.65NKK1089 pKa = 9.26MSNMKK1094 pKa = 9.76YY1095 pKa = 9.76KK1096 pKa = 10.43KK1097 pKa = 9.99HH1098 pKa = 5.98YY1099 pKa = 10.64DD1100 pKa = 3.44LVKK1103 pKa = 10.75LDD1105 pKa = 3.87IEE1107 pKa = 4.22QLLTVNLEE1115 pKa = 3.8IVKK1118 pKa = 10.35ISTNTLEE1125 pKa = 4.77LLRR1128 pKa = 11.84HH1129 pKa = 6.09AKK1131 pKa = 10.02PNIVVDD1137 pKa = 4.05VKK1139 pKa = 10.72HH1140 pKa = 5.69GHH1142 pKa = 6.21EE1143 pKa = 4.21FLQTTSLSQDD1153 pKa = 2.93SMEE1156 pKa = 4.86LEE1158 pKa = 4.3TVEE1161 pKa = 4.74IPVKK1165 pKa = 10.66FSALMNLLNDD1175 pKa = 3.4SSKK1178 pKa = 9.94TVLEE1182 pKa = 4.01HH1183 pKa = 7.98DD1184 pKa = 3.65KK1185 pKa = 10.29LTRR1188 pKa = 11.84HH1189 pKa = 5.93YY1190 pKa = 11.12NVALTNTIDD1199 pKa = 3.6EE1200 pKa = 4.82LYY1202 pKa = 10.21EE1203 pKa = 4.1AEE1205 pKa = 3.83ITEE1208 pKa = 5.02AIRR1211 pKa = 11.84IFLKK1215 pKa = 10.82CKK1217 pKa = 10.25FGANITNYY1225 pKa = 10.6HH1226 pKa = 6.17KK1227 pKa = 10.49MRR1229 pKa = 11.84VIKK1232 pKa = 10.65RR1233 pKa = 11.84FDD1235 pKa = 3.57DD1236 pKa = 4.94LIEE1239 pKa = 4.6LEE1241 pKa = 4.68NLDD1244 pKa = 4.32LPKK1247 pKa = 10.86LKK1249 pKa = 10.89VGDD1252 pKa = 4.58IIHH1255 pKa = 7.23LSHH1258 pKa = 6.67QSNMIAVPILKK1269 pKa = 8.48TRR1271 pKa = 11.84HH1272 pKa = 4.59NTLVVKK1278 pKa = 9.63ITGVRR1283 pKa = 11.84VGVQLLFGITKK1294 pKa = 9.85EE1295 pKa = 4.46SAGSMIRR1302 pKa = 11.84RR1303 pKa = 11.84IFGLLRR1309 pKa = 11.84VPKK1312 pKa = 10.42LSNKK1316 pKa = 9.8LFEE1319 pKa = 4.21QLSNTEE1325 pKa = 4.18CVLAVPGAGKK1335 pKa = 8.73TYY1337 pKa = 10.59EE1338 pKa = 4.18ILNSYY1343 pKa = 9.32NAGDD1347 pKa = 5.01CIIAMTSHH1355 pKa = 6.42NKK1357 pKa = 9.54SSIYY1361 pKa = 10.14RR1362 pKa = 11.84RR1363 pKa = 11.84AKK1365 pKa = 9.58EE1366 pKa = 3.58MKK1368 pKa = 10.03KK1369 pKa = 9.77IVNVKK1374 pKa = 10.14SLEE1377 pKa = 4.1KK1378 pKa = 10.38FLSEE1382 pKa = 3.66GKK1384 pKa = 10.1KK1385 pKa = 10.6YY1386 pKa = 9.05KK1387 pKa = 9.43TVYY1390 pKa = 10.52LDD1392 pKa = 3.0EE1393 pKa = 4.67CTLVKK1398 pKa = 10.56PFDD1401 pKa = 3.89GVLVLTLCDD1410 pKa = 3.25KK1411 pKa = 10.58MYY1413 pKa = 10.82AYY1415 pKa = 10.49GDD1417 pKa = 3.55NNQIPFVDD1425 pKa = 4.44MSQSAGTRR1433 pKa = 11.84EE1434 pKa = 4.21VKK1436 pKa = 10.76NITDD1440 pKa = 3.39VVKK1443 pKa = 10.58PEE1445 pKa = 4.27KK1446 pKa = 10.43IEE1448 pKa = 4.1TKK1450 pKa = 10.24LLSRR1454 pKa = 11.84RR1455 pKa = 11.84FGPSLVSEE1463 pKa = 4.88LSPLIPGIMCHH1474 pKa = 6.6PSVEE1478 pKa = 4.25HH1479 pKa = 6.55DD1480 pKa = 3.13TDD1482 pKa = 3.24IRR1484 pKa = 11.84FANYY1488 pKa = 7.98EE1489 pKa = 4.07KK1490 pKa = 11.18NSIQVTAEE1498 pKa = 3.4IEE1500 pKa = 4.2NNVRR1504 pKa = 11.84NFKK1507 pKa = 10.64PNVVLVFFQAKK1518 pKa = 8.76KK1519 pKa = 10.67AFWLKK1524 pKa = 9.73RR1525 pKa = 11.84LHH1527 pKa = 6.64PIVVEE1532 pKa = 4.51TVHH1535 pKa = 6.8SYY1537 pKa = 10.38QGNEE1541 pKa = 3.61ADD1543 pKa = 3.46NVVVIQEE1550 pKa = 4.32PNEE1553 pKa = 4.19STFGICADD1561 pKa = 3.3KK1562 pKa = 10.85KK1563 pKa = 9.79YY1564 pKa = 10.75VISAASRR1571 pKa = 11.84AVKK1574 pKa = 10.08HH1575 pKa = 6.01LFWISIGMYY1584 pKa = 8.15QHH1586 pKa = 6.57NKK1588 pKa = 8.64GLSSRR1593 pKa = 11.84VYY1595 pKa = 8.99TLSPQRR1601 pKa = 11.84GGGIHH1606 pKa = 5.78KK1607 pKa = 8.22TFNAILDD1614 pKa = 4.38NITGVEE1620 pKa = 4.24MVSNTGTMIDD1630 pKa = 3.41ADD1632 pKa = 4.07KK1633 pKa = 11.24FNASKK1638 pKa = 10.52SAYY1641 pKa = 7.38EE1642 pKa = 3.98DD1643 pKa = 3.52KK1644 pKa = 11.45YY1645 pKa = 10.73GVKK1648 pKa = 10.46VSLANNSDD1656 pKa = 3.6GQSLEE1661 pKa = 3.78VRR1663 pKa = 11.84KK1664 pKa = 10.56VGILMVRR1671 pKa = 11.84FDD1673 pKa = 4.08IVNGVATTSYY1683 pKa = 11.37DD1684 pKa = 3.46RR1685 pKa = 11.84LNMVTSKK1692 pKa = 10.94DD1693 pKa = 3.61LSDD1696 pKa = 4.31LNEE1699 pKa = 4.12LLKK1702 pKa = 10.57PAVIQCDD1709 pKa = 3.44KK1710 pKa = 11.06FDD1712 pKa = 3.76TKK1714 pKa = 11.11FNTTIDD1720 pKa = 3.74SQQADD1725 pKa = 3.59IITFNMQLSALHH1737 pKa = 5.97SACASTQVTFYY1748 pKa = 11.18NDD1750 pKa = 3.11STEE1753 pKa = 3.78VSIICRR1759 pKa = 11.84TTHH1762 pKa = 4.78NKK1764 pKa = 9.1FRR1766 pKa = 11.84ISLSLNDD1773 pKa = 4.59DD1774 pKa = 3.65YY1775 pKa = 11.56CLKK1778 pKa = 8.82VQPMIIGRR1786 pKa = 11.84NFEE1789 pKa = 4.29THH1791 pKa = 4.22VHH1793 pKa = 5.73NVLTTLGYY1801 pKa = 9.65QDD1803 pKa = 4.29GSEE1806 pKa = 4.65EE1807 pKa = 4.57YY1808 pKa = 9.26PFSPAEE1814 pKa = 4.25PIKK1817 pKa = 8.76TTVINHH1823 pKa = 6.36TFNQIMNYY1831 pKa = 9.72LKK1833 pKa = 9.94TVVPDD1838 pKa = 4.11IIEE1841 pKa = 4.08QKK1843 pKa = 10.28MSDD1846 pKa = 3.17SKK1848 pKa = 11.58KK1849 pKa = 10.13FLNKK1853 pKa = 9.41ICEE1856 pKa = 4.22LTKK1859 pKa = 10.42EE1860 pKa = 4.05NEE1862 pKa = 3.88MVLLHH1867 pKa = 5.54NHH1869 pKa = 5.04EE1870 pKa = 4.44TGCYY1874 pKa = 7.9VVKK1877 pKa = 10.14TPINYY1882 pKa = 9.3KK1883 pKa = 10.34CVTPKK1888 pKa = 9.66CTYY1891 pKa = 8.18NTNAYY1896 pKa = 7.83NALMIFLNATSFKK1909 pKa = 9.24TSAMTILRR1917 pKa = 11.84LLTKK1921 pKa = 10.29SLIGSRR1927 pKa = 11.84TDD1929 pKa = 3.22NGIEE1933 pKa = 3.93GLMLPWHH1940 pKa = 5.2YY1941 pKa = 10.91HH1942 pKa = 4.6KK1943 pKa = 9.44THH1945 pKa = 5.76ATKK1948 pKa = 10.64AFKK1951 pKa = 10.42HH1952 pKa = 6.05YY1953 pKa = 9.77IDD1955 pKa = 4.8KK1956 pKa = 11.03SALLYY1961 pKa = 6.76MTSKK1965 pKa = 10.14IGEE1968 pKa = 4.05KK1969 pKa = 8.77RR1970 pKa = 11.84TIYY1973 pKa = 9.41VTEE1976 pKa = 3.89QNRR1979 pKa = 11.84DD1980 pKa = 3.02KK1981 pKa = 11.03IMNMVRR1987 pKa = 11.84DD1988 pKa = 3.65AGIDD1992 pKa = 3.44VNVNIHH1998 pKa = 6.48RR1999 pKa = 11.84FCPSLPLGVEE2009 pKa = 3.82IVGVLMVLSLDD2020 pKa = 4.09KK2021 pKa = 11.06SKK2023 pKa = 10.98QDD2025 pKa = 3.39RR2026 pKa = 11.84KK2027 pKa = 9.96IKK2029 pKa = 10.24IYY2031 pKa = 10.41GPHH2034 pKa = 6.67AGVLAANGFLNLQKK2048 pKa = 10.47VRR2050 pKa = 11.84DD2051 pKa = 3.84YY2052 pKa = 11.52HH2053 pKa = 6.41EE2054 pKa = 4.56LSTYY2058 pKa = 9.03EE2059 pKa = 3.79LHH2061 pKa = 7.48AVDD2064 pKa = 6.12DD2065 pKa = 4.46RR2066 pKa = 11.84MLSSVKK2072 pKa = 10.56NSVSEE2077 pKa = 4.03ALKK2080 pKa = 10.63KK2081 pKa = 10.64KK2082 pKa = 10.58QFDD2085 pKa = 3.59NTNTEE2090 pKa = 3.87KK2091 pKa = 11.09DD2092 pKa = 3.55DD2093 pKa = 4.33AFIKK2097 pKa = 10.76ALEE2100 pKa = 4.26TPNEE2104 pKa = 3.68INYY2107 pKa = 9.59AALYY2111 pKa = 9.89GYY2113 pKa = 10.33DD2114 pKa = 3.65YY2115 pKa = 11.86NLITNSNLLTDD2126 pKa = 4.28LSEE2129 pKa = 4.5FEE2131 pKa = 4.42TVKK2134 pKa = 11.02LITDD2138 pKa = 4.33LDD2140 pKa = 4.33SIEE2143 pKa = 4.12QCTEE2147 pKa = 3.86GSPTFVDD2154 pKa = 3.07NPMWQFTFKK2163 pKa = 10.4IPKK2166 pKa = 9.11ILNALIQTGADD2177 pKa = 3.49EE2178 pKa = 4.96NKK2180 pKa = 10.24LLSYY2184 pKa = 11.06DD2185 pKa = 3.63STFVGLGAVVGDD2197 pKa = 3.99IEE2199 pKa = 4.77QGVSKK2204 pKa = 10.55QLYY2207 pKa = 7.85SQLAGFVLRR2216 pKa = 11.84DD2217 pKa = 3.76QITLTVPRR2225 pKa = 11.84LNSSMIDD2232 pKa = 3.3GEE2234 pKa = 4.81VNVTSQEE2241 pKa = 3.77ITVSRR2246 pKa = 11.84KK2247 pKa = 9.03LFRR2250 pKa = 11.84DD2251 pKa = 3.21CGLRR2255 pKa = 11.84LLRR2258 pKa = 11.84EE2259 pKa = 3.86NHH2261 pKa = 7.29DD2262 pKa = 3.25IDD2264 pKa = 4.94SLLKK2268 pKa = 9.98HH2269 pKa = 6.14VRR2271 pKa = 11.84TKK2273 pKa = 10.09QHH2275 pKa = 4.67ATYY2278 pKa = 10.19YY2279 pKa = 9.87SDD2281 pKa = 3.01SGSYY2285 pKa = 9.38RR2286 pKa = 11.84QYY2288 pKa = 11.41KK2289 pKa = 6.34EE2290 pKa = 4.22TPGAAMDD2297 pKa = 4.2LCLAVYY2303 pKa = 10.39LRR2305 pKa = 11.84YY2306 pKa = 9.99NNKK2309 pKa = 8.16FTEE2312 pKa = 4.42LFDD2315 pKa = 4.28TIKK2318 pKa = 9.96WLQPEE2323 pKa = 4.45TVKK2326 pKa = 10.93QEE2328 pKa = 4.57GIFEE2332 pKa = 4.67LLLDD2336 pKa = 4.26NLGSSAKK2343 pKa = 10.33EE2344 pKa = 3.5MVLNVVSKK2352 pKa = 10.89LSGIAGMNLPQKK2364 pKa = 10.84DD2365 pKa = 4.26FIKK2368 pKa = 9.96TIWKK2372 pKa = 9.25VVRR2375 pKa = 11.84NMAFHH2380 pKa = 6.11QEE2382 pKa = 3.91DD2383 pKa = 4.38MFTEE2387 pKa = 4.63TMSVMNVEE2395 pKa = 4.29EE2396 pKa = 4.7RR2397 pKa = 11.84ISTRR2401 pKa = 11.84RR2402 pKa = 11.84LLMRR2406 pKa = 11.84GTKK2409 pKa = 9.64QILMTSGAASIDD2421 pKa = 3.31EE2422 pKa = 4.53GANKK2426 pKa = 8.26VTLQSKK2432 pKa = 9.26YY2433 pKa = 7.93LHH2435 pKa = 6.55KK2436 pKa = 10.69LFSNMSTLMQSVSARR2451 pKa = 11.84HH2452 pKa = 6.44DD2453 pKa = 3.58PVTLMKK2459 pKa = 10.86DD2460 pKa = 3.2FTKK2463 pKa = 10.45PKK2465 pKa = 9.87SICCICIGSFGDD2477 pKa = 3.56ITNHH2481 pKa = 5.58LQVANMAVHH2490 pKa = 6.61EE2491 pKa = 4.46GVKK2494 pKa = 10.51VSLIFPDD2501 pKa = 3.69SYY2503 pKa = 11.2LDD2505 pKa = 3.61QVRR2508 pKa = 11.84SIADD2512 pKa = 3.42SKK2514 pKa = 10.05VTLVPQRR2521 pKa = 11.84FSVDD2525 pKa = 3.05NHH2527 pKa = 5.8IKK2529 pKa = 10.55LLNEE2533 pKa = 3.76LRR2535 pKa = 11.84TDD2537 pKa = 3.45NLEE2540 pKa = 4.31VLMTAYY2546 pKa = 9.6TEE2548 pKa = 4.21EE2549 pKa = 4.51KK2550 pKa = 10.71GALLYY2555 pKa = 11.03NDD2557 pKa = 4.54FDD2559 pKa = 4.69YY2560 pKa = 11.32KK2561 pKa = 10.44ILKK2564 pKa = 9.13PDD2566 pKa = 3.9LVVGTCLTVQGPIIAKK2582 pKa = 9.79KK2583 pKa = 10.15FNANYY2588 pKa = 10.62LEE2590 pKa = 4.85LNALPWNLVRR2600 pKa = 11.84AEE2602 pKa = 4.06NKK2604 pKa = 10.31RR2605 pKa = 11.84FDD2607 pKa = 3.51SLKK2610 pKa = 8.65NVLYY2614 pKa = 10.27RR2615 pKa = 11.84GYY2617 pKa = 10.83RR2618 pKa = 11.84AMQLEE2623 pKa = 4.81TIIKK2627 pKa = 8.87QYY2629 pKa = 11.2AIAGLQNPTPQDD2641 pKa = 3.65IISEE2645 pKa = 4.46NYY2647 pKa = 8.94TSVNVIDD2654 pKa = 5.16PIFGLVAEE2662 pKa = 4.91KK2663 pKa = 10.59EE2664 pKa = 4.15NHH2666 pKa = 5.82SVVGFLPFKK2675 pKa = 8.86YY2676 pKa = 8.87TNSKK2680 pKa = 9.23TILTTKK2686 pKa = 9.58TCVLTLGSMKK2696 pKa = 10.18TKK2698 pKa = 10.01QHH2700 pKa = 5.52ANKK2703 pKa = 9.83LISVAKK2709 pKa = 9.85KK2710 pKa = 8.92LLSFGEE2716 pKa = 4.24HH2717 pKa = 3.91VTIVEE2722 pKa = 4.3GGVKK2726 pKa = 10.12FNKK2729 pKa = 9.92EE2730 pKa = 3.82FIDD2733 pKa = 5.09RR2734 pKa = 11.84SDD2736 pKa = 3.31KK2737 pKa = 11.09LQIVSNVDD2745 pKa = 3.1YY2746 pKa = 10.37TSQLVHH2752 pKa = 6.75CKK2754 pKa = 10.41LMLHH2758 pKa = 6.5HH2759 pKa = 6.95CGSGTTHH2766 pKa = 6.48TAMLAGLPQILLPVDD2781 pKa = 4.39FDD2783 pKa = 3.66QPQWAGALNKK2793 pKa = 9.99KK2794 pKa = 10.37GYY2796 pKa = 9.98GVYY2799 pKa = 10.49ADD2801 pKa = 4.41EE2802 pKa = 4.85LLNMEE2807 pKa = 5.4LDD2809 pKa = 5.51DD2810 pKa = 3.83FTHH2813 pKa = 6.67WFNVTLEE2820 pKa = 4.1KK2821 pKa = 10.38TKK2823 pKa = 11.02NDD2825 pKa = 3.42SNKK2828 pKa = 9.62MIRR2831 pKa = 11.84HH2832 pKa = 5.36TATNIAHH2839 pKa = 6.94ALKK2842 pKa = 9.43LTDD2845 pKa = 3.53NAITDD2850 pKa = 4.25SVTLTTDD2857 pKa = 2.72ITIEE2861 pKa = 3.88EE2862 pKa = 4.05EE2863 pKa = 4.41AIIRR2867 pKa = 11.84DD2868 pKa = 4.05NIHH2871 pKa = 6.17KK2872 pKa = 10.69CNLHH2876 pKa = 5.28KK2877 pKa = 10.72CKK2879 pKa = 9.83PLEE2882 pKa = 4.2TMSVLINTCCGEE2894 pKa = 4.18RR2895 pKa = 11.84KK2896 pKa = 8.25RR2897 pKa = 11.84HH2898 pKa = 4.98CVIGEE2903 pKa = 4.06TEE2905 pKa = 3.72EE2906 pKa = 4.69CYY2908 pKa = 10.51IIVNSTHH2915 pKa = 6.24YY2916 pKa = 9.58PDD2918 pKa = 6.03HH2919 pKa = 7.13RR2920 pKa = 11.84IGWNRR2925 pKa = 11.84KK2926 pKa = 5.56QHH2928 pKa = 6.28IAIQPIMPIPVLRR2941 pKa = 11.84GHH2943 pKa = 6.07YY2944 pKa = 9.82EE2945 pKa = 3.7IATLGYY2951 pKa = 8.82HH2952 pKa = 5.3AHH2954 pKa = 6.51GMCEE2958 pKa = 4.44ANSEE2962 pKa = 4.48SPPNFYY2968 pKa = 10.34IKK2970 pKa = 10.15PNQVSEE2976 pKa = 4.34FNKK2979 pKa = 10.7SIDD2982 pKa = 3.49WIDD2985 pKa = 3.9LVRR2988 pKa = 11.84LHH2990 pKa = 6.57NGRR2993 pKa = 11.84WSNRR2997 pKa = 11.84GVFGIEE3003 pKa = 3.78PRR3005 pKa = 11.84TGICNCCHH3013 pKa = 6.83RR3014 pKa = 11.84SMWLLRR3020 pKa = 11.84SQNEE3024 pKa = 4.15KK3025 pKa = 10.82LCTSCHH3031 pKa = 5.46IQINWPQFTFTDD3043 pKa = 3.89SVSTTKK3049 pKa = 10.39TDD3051 pKa = 3.1NFKK3054 pKa = 10.62AKK3056 pKa = 10.03SRR3058 pKa = 11.84AGHH3061 pKa = 6.92IIFEE3065 pKa = 4.27LSKK3068 pKa = 10.55LQEE3071 pKa = 4.15SHH3073 pKa = 6.98VLLDD3077 pKa = 3.59PKK3079 pKa = 11.07GNSNCVPNCLRR3090 pKa = 11.84AVAKK3094 pKa = 10.63YY3095 pKa = 7.16STKK3098 pKa = 10.3VSSTINNAFIDD3109 pKa = 3.82FEE3111 pKa = 4.72IGEE3114 pKa = 4.27FTSIEE3119 pKa = 4.34KK3120 pKa = 10.04IIQICRR3126 pKa = 11.84FMRR3129 pKa = 11.84VDD3131 pKa = 3.19IQVDD3135 pKa = 3.58HH3136 pKa = 7.28PNVKK3140 pKa = 9.12TGGRR3144 pKa = 11.84LLHH3147 pKa = 6.34NLEE3150 pKa = 4.07FDD3152 pKa = 3.5KK3153 pKa = 11.08TPKK3156 pKa = 10.21LRR3158 pKa = 11.84LLITGEE3164 pKa = 4.13RR3165 pKa = 11.84EE3166 pKa = 3.92QHH3168 pKa = 5.56CTLTAAIKK3176 pKa = 10.36IPAAQKK3182 pKa = 10.61SITLIEE3188 pKa = 4.34TEE3190 pKa = 4.46NPCDD3194 pKa = 4.84DD3195 pKa = 4.21MNSLITTDD3203 pKa = 5.2LIDD3206 pKa = 4.27NADD3209 pKa = 3.34MDD3211 pKa = 4.39FNQILKK3217 pKa = 9.46TNLKK3221 pKa = 8.02TFRR3224 pKa = 11.84STKK3227 pKa = 8.02YY3228 pKa = 8.22TDD3230 pKa = 4.14VIAKK3234 pKa = 6.67TTDD3237 pKa = 2.88GKK3239 pKa = 11.34LNIYY3243 pKa = 9.05GRR3245 pKa = 11.84RR3246 pKa = 11.84NLLVEE3251 pKa = 3.99ANIVFRR3257 pKa = 11.84KK3258 pKa = 9.55FKK3260 pKa = 9.6SHH3262 pKa = 5.61EE3263 pKa = 4.19MYY3265 pKa = 10.58FGEE3268 pKa = 4.95LPEE3271 pKa = 4.26SFNRR3275 pKa = 11.84FEE3277 pKa = 5.64DD3278 pKa = 4.79RR3279 pKa = 11.84ILCVPTRR3286 pKa = 11.84TGNVIGLVTRR3296 pKa = 11.84LNNTEE3301 pKa = 3.78KK3302 pKa = 10.77QLIVLTGQRR3311 pKa = 11.84PLPVVNYY3318 pKa = 10.18VIDD3321 pKa = 4.1ASVSITKK3328 pKa = 9.62VKK3330 pKa = 10.06KK3331 pKa = 9.67HH3332 pKa = 6.04KK3333 pKa = 10.57KK3334 pKa = 9.31LIKK3337 pKa = 10.17NDD3339 pKa = 3.59TVTVGAFNEE3348 pKa = 4.07KK3349 pKa = 9.98SRR3351 pKa = 11.84RR3352 pKa = 11.84EE3353 pKa = 3.89LSTIYY3358 pKa = 10.24PGISVNRR3365 pKa = 11.84NCQKK3369 pKa = 10.65VVISSLDD3376 pKa = 3.42TRR3378 pKa = 11.84NHH3380 pKa = 5.86HH3381 pKa = 7.25LYY3383 pKa = 10.75SEE3385 pKa = 4.29WNEE3388 pKa = 3.56MHH3390 pKa = 6.68TLLNRR3395 pKa = 11.84NTMGEE3400 pKa = 4.26TLIEE3404 pKa = 4.34LYY3406 pKa = 10.87GKK3408 pKa = 10.47LDD3410 pKa = 3.65GATVPTLVDD3419 pKa = 3.65SNLTQSICEE3428 pKa = 3.94QFSRR3432 pKa = 11.84TTRR3435 pKa = 11.84DD3436 pKa = 3.06QIFRR3440 pKa = 11.84FGWDD3444 pKa = 2.99QKK3446 pKa = 10.02PTVEE3450 pKa = 3.47TWTRR3454 pKa = 11.84DD3455 pKa = 3.14KK3456 pKa = 10.66PTGLFLEE3463 pKa = 4.68EE3464 pKa = 4.1QGFTSPEE3471 pKa = 3.67NEE3473 pKa = 4.14RR3474 pKa = 11.84YY3475 pKa = 9.95VLDD3478 pKa = 3.64YY3479 pKa = 11.13EE3480 pKa = 4.26QFKK3483 pKa = 10.92DD3484 pKa = 3.52ISEE3487 pKa = 4.59LNDD3490 pKa = 3.4TEE3492 pKa = 4.54TMNKK3496 pKa = 10.14LISCDD3501 pKa = 3.74LIGYY3505 pKa = 9.73ISLKK3509 pKa = 10.39NCVKK3513 pKa = 9.92YY3514 pKa = 10.16FEE3516 pKa = 5.41IIKK3519 pKa = 8.76STEE3522 pKa = 4.31DD3523 pKa = 2.79IVAFTGVDD3531 pKa = 3.24KK3532 pKa = 11.77NEE3534 pKa = 4.37LNRR3537 pKa = 11.84EE3538 pKa = 4.18LIDD3541 pKa = 3.7YY3542 pKa = 10.65DD3543 pKa = 3.99EE3544 pKa = 5.53ASLTVTCGPIWKK3556 pKa = 9.84GGLPEE3561 pKa = 4.09ITTMDD3566 pKa = 3.71SLNRR3570 pKa = 11.84TVFVRR3575 pKa = 11.84PEE3577 pKa = 4.45DD3578 pKa = 3.42IKK3580 pKa = 11.18EE3581 pKa = 4.39SNGEE3585 pKa = 3.84LTLVWFRR3592 pKa = 11.84SNCLILTTFVWKK3604 pKa = 10.48KK3605 pKa = 9.22KK3606 pKa = 9.46VRR3608 pKa = 11.84GGSYY3612 pKa = 9.88GQKK3615 pKa = 9.87QDD3617 pKa = 4.89LEE3619 pKa = 4.24DD3620 pKa = 3.63RR3621 pKa = 11.84KK3622 pKa = 10.93QNIDD3626 pKa = 3.11SDD3628 pKa = 4.19NNKK3631 pKa = 10.21LYY3633 pKa = 10.14WFNEE3637 pKa = 4.27EE3638 pKa = 3.46IEE3640 pKa = 4.25EE3641 pKa = 4.13RR3642 pKa = 11.84LEE3644 pKa = 3.99HH3645 pKa = 6.84RR3646 pKa = 11.84GAEE3649 pKa = 3.93SWIDD3653 pKa = 3.39KK3654 pKa = 10.47GSKK3657 pKa = 9.4PKK3659 pKa = 9.08NTQLPALAANEE3670 pKa = 4.3VEE3672 pKa = 5.32LDD3674 pKa = 3.7ALCSVFNDD3682 pKa = 3.32GMRR3685 pKa = 11.84GYY3687 pKa = 10.55DD3688 pKa = 2.8GKK3690 pKa = 9.17TFVASEE3696 pKa = 3.92PANKK3700 pKa = 9.44KK3701 pKa = 9.88FLMFTEE3707 pKa = 5.01PDD3709 pKa = 3.37TPNFVCHH3716 pKa = 5.43EE3717 pKa = 4.23TGEE3720 pKa = 4.37GPEE3723 pKa = 4.19IGTEE3727 pKa = 4.02VMDD3730 pKa = 6.0IIDD3733 pKa = 4.77DD3734 pKa = 3.72VDD3736 pKa = 4.14LADD3739 pKa = 3.89HH3740 pKa = 5.72VTRR3743 pKa = 11.84LAPKK3747 pKa = 8.26TGIIKK3752 pKa = 9.61SHH3754 pKa = 5.77EE3755 pKa = 3.99VPGRR3759 pKa = 11.84IVTNTKK3765 pKa = 7.01TTMVKK3770 pKa = 9.86YY3771 pKa = 10.36PEE3773 pKa = 4.04MSKK3776 pKa = 10.63PVITKK3781 pKa = 10.01GVYY3784 pKa = 6.69QTFNAVSSRR3793 pKa = 11.84LHH3795 pKa = 6.23SVVKK3799 pKa = 10.0YY3800 pKa = 9.77RR3801 pKa = 11.84KK3802 pKa = 8.91HH3803 pKa = 7.3KK3804 pKa = 9.22MDD3806 pKa = 3.27VVSEE3810 pKa = 4.09FDD3812 pKa = 3.14RR3813 pKa = 11.84CANCYY3818 pKa = 8.19FVPNYY3823 pKa = 9.63QHH3825 pKa = 6.93VLDD3828 pKa = 4.68EE3829 pKa = 4.9FKK3831 pKa = 11.07NDD3833 pKa = 4.29PITYY3837 pKa = 9.07NVNNIVDD3844 pKa = 3.54WVNRR3848 pKa = 11.84RR3849 pKa = 11.84KK3850 pKa = 10.34NSSVVAAEE3858 pKa = 4.98LIEE3861 pKa = 4.34LMQTGWFNHH3870 pKa = 7.06PINSVKK3876 pKa = 10.11VHH3878 pKa = 6.3SKK3880 pKa = 11.03LEE3882 pKa = 4.1SLLKK3886 pKa = 10.19EE3887 pKa = 4.29DD3888 pKa = 4.72EE3889 pKa = 4.0IGYY3892 pKa = 10.15QYY3894 pKa = 10.88GQQKK3898 pKa = 9.4IRR3900 pKa = 11.84IIVHH3904 pKa = 3.57QTYY3907 pKa = 10.45AICAIFADD3915 pKa = 3.84IFLQAKK3921 pKa = 9.32EE3922 pKa = 4.18RR3923 pKa = 11.84FKK3925 pKa = 11.19QLLGEE3930 pKa = 4.2KK3931 pKa = 9.77CVYY3934 pKa = 11.1ADD3936 pKa = 3.56GFTLEE3941 pKa = 4.02EE3942 pKa = 3.69LAARR3946 pKa = 11.84MRR3948 pKa = 11.84LIKK3951 pKa = 9.92SDD3953 pKa = 3.15KK3954 pKa = 9.23PLWVFEE3960 pKa = 4.44RR3961 pKa = 11.84DD3962 pKa = 3.24FTKK3965 pKa = 10.34QDD3967 pKa = 3.16RR3968 pKa = 11.84QTDD3971 pKa = 3.3EE3972 pKa = 4.91DD3973 pKa = 4.77LINFEE3978 pKa = 4.25MYY3980 pKa = 10.13VYY3982 pKa = 10.32KK3983 pKa = 10.51QLGVHH3988 pKa = 7.14DD3989 pKa = 4.87DD3990 pKa = 4.3VISFWRR3996 pKa = 11.84KK3997 pKa = 5.64THH3999 pKa = 6.19EE4000 pKa = 3.37NWFYY4004 pKa = 11.37KK4005 pKa = 9.92GTDD4008 pKa = 3.44LSGSLSWMRR4017 pKa = 11.84LTGQCTTALGNAITNMVVNSRR4038 pKa = 11.84TYY4040 pKa = 10.44QEE4042 pKa = 4.14YY4043 pKa = 9.5EE4044 pKa = 3.87QNIKK4048 pKa = 10.39IMLLLGDD4055 pKa = 4.8DD4056 pKa = 3.76NSMISDD4062 pKa = 4.07CEE4064 pKa = 4.27INVHH4068 pKa = 5.55NSRR4071 pKa = 11.84KK4072 pKa = 9.51ISRR4075 pKa = 11.84DD4076 pKa = 3.48YY4077 pKa = 11.78YY4078 pKa = 11.29NMEE4081 pKa = 4.5SKK4083 pKa = 10.77DD4084 pKa = 3.47FCKK4087 pKa = 10.36KK4088 pKa = 8.62HH4089 pKa = 5.21TGIFLRR4095 pKa = 11.84MILHH4099 pKa = 5.22QQQDD4103 pKa = 3.88GSMSVCPDD4111 pKa = 3.53FLRR4114 pKa = 11.84LRR4116 pKa = 11.84RR4117 pKa = 11.84RR4118 pKa = 11.84YY4119 pKa = 8.62EE4120 pKa = 3.81VTNGVHH4126 pKa = 6.98KK4127 pKa = 10.77MGDD4130 pKa = 3.52EE4131 pKa = 3.98EE4132 pKa = 4.61LKK4134 pKa = 11.09LRR4136 pKa = 11.84GLSYY4140 pKa = 11.19LYY4142 pKa = 9.89MLGRR4146 pKa = 11.84NKK4148 pKa = 8.9VTEE4151 pKa = 4.1EE4152 pKa = 3.93AVTSLGYY4159 pKa = 10.37NDD4161 pKa = 4.85EE4162 pKa = 4.76LLPTYY4167 pKa = 11.01YY4168 pKa = 10.66NFEE4171 pKa = 4.18EE4172 pKa = 4.42AVMAVATNNGMTNDD4186 pKa = 3.46AARR4189 pKa = 11.84NEE4191 pKa = 4.11FNLLIDD4197 pKa = 4.01MIKK4200 pKa = 10.67ANKK4203 pKa = 10.01SYY4205 pKa = 11.25DD4206 pKa = 3.02VDD4208 pKa = 4.09YY4209 pKa = 11.29VVTSSQIRR4217 pKa = 3.39

Molecular weight: 478.17 kDa
Isoelectric point according different methods:

Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try ESI

ChTry ESI

ArgC ESI

LysN ESI

TryLysC ESI

Try MALDI

ChTry MALDI

ArgC MALDI

LysN MALDI

TryLysC MALDI

Try LTQ

ChTry LTQ

ArgC LTQ

LysN LTQ

TryLysC LTQ

Try MSlow

ChTry MSlow

ArgC MSlow

LysN MSlow

TryLysC MSlow

Try MShigh

ChTry MShigh

ArgC MShigh

LysN MShigh

TryLysC MShigh

General Statistics

Number of major isoforms	Number of additional isoforms	Number of all proteins	Number of amino acids	Min. Seq. Length	Max. Seq. Length	Avg. Seq. Length	Avg. Mol. Weight
1	0	1	4217	4217	4217	4217.0	478.17

Amino acid frequency

Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu
4.695 ± 0.0	2.182 ± 0.0	5.81 ± 0.0	6.26 ± 0.0	3.818 ± 0.0	4.743 ± 0.0	3.059 ± 0.0	6.924 ± 0.0	7.161 ± 0.0	9.628 ± 0.0

Met	Asn	Gln	Pro	Arg	Ser	Thr	Val	Trp	Tyr
2.466 ± 0.0	7.043 ± 0.0	3.391 ± 0.0	2.988 ± 0.0	3.913 ± 0.0	6.498 ± 0.0	7.754 ± 0.0	7.256 ± 0.0	0.901 ± 0.0	3.51 ± 0.0

Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here

See this proteome in:

Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski