Amino acid dipepetide frequency for Zhaonella formicivorans

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	8.803AlaAla: 8.803 ± 0.12	1.05AlaCys: 1.05 ± 0.036	3.795AlaAsp: 3.795 ± 0.065	6.313AlaGlu: 6.313 ± 0.088	3.194AlaPhe: 3.194 ± 0.063	7.458AlaGly: 7.458 ± 0.107	1.361AlaHis: 1.361 ± 0.042	5.712AlaIle: 5.712 ± 0.083	5.698AlaLys: 5.698 ± 0.089	9.543AlaLeu: 9.543 ± 0.101	2.351AlaMet: 2.351 ± 0.049	2.815AlaAsn: 2.815 ± 0.052	2.693AlaPro: 2.693 ± 0.054	3.072AlaGln: 3.072 ± 0.056	4.27AlaArg: 4.27 ± 0.066	4.087AlaSer: 4.087 ± 0.065	3.671AlaThr: 3.671 ± 0.061	7.274AlaVal: 7.274 ± 0.102	0.73AlaTrp: 0.73 ± 0.028	2.358AlaTyr: 2.358 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	0.882CysAla: 0.882 ± 0.03	0.215CysCys: 0.215 ± 0.016	0.494CysAsp: 0.494 ± 0.023	0.56CysGlu: 0.56 ± 0.023	0.48CysPhe: 0.48 ± 0.022	1.202CysGly: 1.202 ± 0.038	0.374CysHis: 0.374 ± 0.038	0.695CysIle: 0.695 ± 0.029	0.608CysLys: 0.608 ± 0.024	1.182CysLeu: 1.182 ± 0.037	0.27CysMet: 0.27 ± 0.018	0.479CysAsn: 0.479 ± 0.022	0.725CysPro: 0.725 ± 0.024	0.439CysGln: 0.439 ± 0.022	0.669CysArg: 0.669 ± 0.027	0.73CysSer: 0.73 ± 0.031	0.651CysThr: 0.651 ± 0.025	0.725CysVal: 0.725 ± 0.026	0.127CysTrp: 0.127 ± 0.012	0.406CysTyr: 0.406 ± 0.023	0.0CysXaa: 0.0 ± 0.0
Asp	3.318AspAla: 3.318 ± 0.068	0.553AspCys: 0.553 ± 0.023	1.838AspAsp: 1.838 ± 0.048	3.034AspGlu: 3.034 ± 0.052	2.143AspPhe: 2.143 ± 0.047	3.073AspGly: 3.073 ± 0.068	0.767AspHis: 0.767 ± 0.027	3.376AspIle: 3.376 ± 0.06	2.827AspLys: 2.827 ± 0.049	5.377AspLeu: 5.377 ± 0.078	1.069AspMet: 1.069 ± 0.033	1.671AspAsn: 1.671 ± 0.038	2.174AspPro: 2.174 ± 0.045	1.205AspGln: 1.205 ± 0.039	2.246AspArg: 2.246 ± 0.042	2.263AspSer: 2.263 ± 0.05	2.061AspThr: 2.061 ± 0.042	3.435AspVal: 3.435 ± 0.058	0.529AspTrp: 0.529 ± 0.024	1.854AspTyr: 1.854 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	6.286GluAla: 6.286 ± 0.079	0.599GluCys: 0.599 ± 0.025	2.981GluAsp: 2.981 ± 0.048	6.24GluGlu: 6.24 ± 0.093	2.336GluPhe: 2.336 ± 0.043	4.442GluGly: 4.442 ± 0.067	1.352GluHis: 1.352 ± 0.035	5.673GluIle: 5.673 ± 0.077	5.483GluLys: 5.483 ± 0.087	7.786GluLeu: 7.786 ± 0.105	1.876GluMet: 1.876 ± 0.042	2.795GluAsn: 2.795 ± 0.048	2.335GluPro: 2.335 ± 0.055	3.189GluGln: 3.189 ± 0.059	3.634GluArg: 3.634 ± 0.064	2.803GluSer: 2.803 ± 0.056	3.065GluThr: 3.065 ± 0.058	5.478GluVal: 5.478 ± 0.076	0.577GluTrp: 0.577 ± 0.025	2.027GluTyr: 2.027 ± 0.05	0.0GluXaa: 0.0 ± 0.0
Phe	3.192PheAla: 3.192 ± 0.064	0.533PheCys: 0.533 ± 0.026	1.821PheAsp: 1.821 ± 0.044	2.073PheGlu: 2.073 ± 0.044	1.781PhePhe: 1.781 ± 0.051	3.175PheGly: 3.175 ± 0.06	0.731PheHis: 0.731 ± 0.027	2.773PheIle: 2.773 ± 0.064	2.373PheLys: 2.373 ± 0.054	4.195PheLeu: 4.195 ± 0.082	0.914PheMet: 0.914 ± 0.027	1.7PheAsn: 1.7 ± 0.041	1.697PhePro: 1.697 ± 0.042	1.222PheGln: 1.222 ± 0.035	1.756PheArg: 1.756 ± 0.042	2.623PheSer: 2.623 ± 0.058	2.166PheThr: 2.166 ± 0.044	2.581PheVal: 2.581 ± 0.055	0.485PheTrp: 0.485 ± 0.023	1.398PheTyr: 1.398 ± 0.036	0.0PheXaa: 0.0 ± 0.0
Gly	6.143GlyAla: 6.143 ± 0.083	1.109GlyCys: 1.109 ± 0.036	3.163GlyAsp: 3.163 ± 0.057	4.869GlyGlu: 4.869 ± 0.066	3.152GlyPhe: 3.152 ± 0.059	5.569GlyGly: 5.569 ± 0.076	1.421GlyHis: 1.421 ± 0.032	6.065GlyIle: 6.065 ± 0.081	5.46GlyLys: 5.46 ± 0.085	8.142GlyLeu: 8.142 ± 0.093	2.26GlyMet: 2.26 ± 0.042	2.664GlyAsn: 2.664 ± 0.063	2.346GlyPro: 2.346 ± 0.044	2.856GlyGln: 2.856 ± 0.057	3.662GlyArg: 3.662 ± 0.062	4.265GlySer: 4.265 ± 0.075	4.096GlyThr: 4.096 ± 0.064	5.658GlyVal: 5.658 ± 0.071	0.817GlyTrp: 0.817 ± 0.032	2.736GlyTyr: 2.736 ± 0.05	0.0GlyXaa: 0.0 ± 0.0
His	1.335HisAla: 1.335 ± 0.032	0.303HisCys: 0.303 ± 0.018	0.86HisAsp: 0.86 ± 0.029	1.033HisGlu: 1.033 ± 0.031	0.785HisPhe: 0.785 ± 0.024	1.447HisGly: 1.447 ± 0.04	0.454HisHis: 0.454 ± 0.025	1.212HisIle: 1.212 ± 0.032	0.974HisLys: 0.974 ± 0.032	2.034HisLeu: 2.034 ± 0.046	0.344HisMet: 0.344 ± 0.019	0.745HisAsn: 0.745 ± 0.032	1.121HisPro: 1.121 ± 0.032	0.714HisGln: 0.714 ± 0.029	0.997HisArg: 0.997 ± 0.029	1.04HisSer: 1.04 ± 0.031	0.892HisThr: 0.892 ± 0.029	1.152HisVal: 1.152 ± 0.032	0.215HisTrp: 0.215 ± 0.015	0.66HisTyr: 0.66 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.516IleAla: 6.516 ± 0.09	0.878IleCys: 0.878 ± 0.03	3.41IleAsp: 3.41 ± 0.062	4.41IleGlu: 4.41 ± 0.065	2.806IlePhe: 2.806 ± 0.051	5.148IleGly: 5.148 ± 0.07	1.223IleHis: 1.223 ± 0.039	5.205IleIle: 5.205 ± 0.087	4.547IleLys: 4.547 ± 0.079	7.087IleLeu: 7.087 ± 0.092	1.599IleMet: 1.599 ± 0.037	2.946IleAsn: 2.946 ± 0.055	3.327IlePro: 3.327 ± 0.059	1.988IleGln: 1.988 ± 0.043	3.159IleArg: 3.159 ± 0.059	4.419IleSer: 4.419 ± 0.071	3.865IleThr: 3.865 ± 0.066	4.877IleVal: 4.877 ± 0.083	0.572IleTrp: 0.572 ± 0.028	2.104IleTyr: 2.104 ± 0.05	0.0IleXaa: 0.0 ± 0.0
Lys	5.622LysAla: 5.622 ± 0.081	0.639LysCys: 0.639 ± 0.027	2.957LysAsp: 2.957 ± 0.059	5.688LysGlu: 5.688 ± 0.088	1.978LysPhe: 1.978 ± 0.045	4.362LysGly: 4.362 ± 0.067	1.163LysHis: 1.163 ± 0.036	4.995LysIle: 4.995 ± 0.079	4.713LysLys: 4.713 ± 0.079	6.357LysLeu: 6.357 ± 0.078	1.709LysMet: 1.709 ± 0.039	2.828LysAsn: 2.828 ± 0.056	2.593LysPro: 2.593 ± 0.061	2.391LysGln: 2.391 ± 0.048	3.031LysArg: 3.031 ± 0.052	3.156LysSer: 3.156 ± 0.059	3.269LysThr: 3.269 ± 0.062	5.063LysVal: 5.063 ± 0.08	0.548LysTrp: 0.548 ± 0.026	2.094LysTyr: 2.094 ± 0.048	0.0LysXaa: 0.0 ± 0.0
Leu	10.6LeuAla: 10.6 ± 0.126	1.13LeuCys: 1.13 ± 0.035	4.852LeuAsp: 4.852 ± 0.069	7.703LeuGlu: 7.703 ± 0.094	3.954LeuPhe: 3.954 ± 0.07	8.265LeuGly: 8.265 ± 0.096	1.899LeuHis: 1.899 ± 0.044	6.495LeuIle: 6.495 ± 0.091	7.21LeuLys: 7.21 ± 0.085	11.061LeuLeu: 11.061 ± 0.14	2.325LeuMet: 2.325 ± 0.049	4.284LeuAsn: 4.284 ± 0.077	4.796LeuPro: 4.796 ± 0.064	4.205LeuGln: 4.205 ± 0.067	5.056LeuArg: 5.056 ± 0.082	6.132LeuSer: 6.132 ± 0.087	5.684LeuThr: 5.684 ± 0.077	7.779LeuVal: 7.779 ± 0.091	0.906LeuTrp: 0.906 ± 0.035	2.799LeuTyr: 2.799 ± 0.056	0.0LeuXaa: 0.0 ± 0.0
Met	2.429MetAla: 2.429 ± 0.047	0.236MetCys: 0.236 ± 0.015	1.241MetAsp: 1.241 ± 0.036	1.806MetGlu: 1.806 ± 0.043	0.835MetPhe: 0.835 ± 0.032	1.868MetGly: 1.868 ± 0.053	0.485MetHis: 0.485 ± 0.024	1.297MetIle: 1.297 ± 0.042	1.433MetLys: 1.433 ± 0.037	2.744MetLeu: 2.744 ± 0.057	0.608MetMet: 0.608 ± 0.027	0.899MetAsn: 0.899 ± 0.029	1.089MetPro: 1.089 ± 0.032	1.043MetGln: 1.043 ± 0.032	1.19MetArg: 1.19 ± 0.039	1.399MetSer: 1.399 ± 0.037	1.207MetThr: 1.207 ± 0.031	1.902MetVal: 1.902 ± 0.043	0.177MetTrp: 0.177 ± 0.011	0.603MetTyr: 0.603 ± 0.027	0.0MetXaa: 0.0 ± 0.0
Asn	2.783AsnAla: 2.783 ± 0.056	0.574AsnCys: 0.574 ± 0.025	1.456AsnAsp: 1.456 ± 0.039	2.19AsnGlu: 2.19 ± 0.047	1.617AsnPhe: 1.617 ± 0.044	2.631AsnGly: 2.631 ± 0.06	0.662AsnHis: 0.662 ± 0.025	3.128AsnIle: 3.128 ± 0.068	2.542AsnLys: 2.542 ± 0.06	4.389AsnLeu: 4.389 ± 0.065	0.917AsnMet: 0.917 ± 0.026	1.758AsnAsn: 1.758 ± 0.048	2.23AsnPro: 2.23 ± 0.047	1.282AsnGln: 1.282 ± 0.037	1.955AsnArg: 1.955 ± 0.045	2.24AsnSer: 2.24 ± 0.051	1.864AsnThr: 1.864 ± 0.044	2.621AsnVal: 2.621 ± 0.054	0.453AsnTrp: 0.453 ± 0.021	1.383AsnTyr: 1.383 ± 0.036	0.0AsnXaa: 0.0 ± 0.0
Pro	3.497ProAla: 3.497 ± 0.068	0.445ProCys: 0.445 ± 0.022	2.08ProAsp: 2.08 ± 0.04	3.853ProGlu: 3.853 ± 0.069	1.746ProPhe: 1.746 ± 0.044	3.761ProGly: 3.761 ± 0.071	0.802ProHis: 0.802 ± 0.029	2.304ProIle: 2.304 ± 0.049	2.31ProLys: 2.31 ± 0.052	4.094ProLeu: 4.094 ± 0.077	0.87ProMet: 0.87 ± 0.03	1.428ProAsn: 1.428 ± 0.04	1.54ProPro: 1.54 ± 0.042	1.538ProGln: 1.538 ± 0.039	1.742ProArg: 1.742 ± 0.038	1.982ProSer: 1.982 ± 0.049	1.944ProThr: 1.944 ± 0.046	3.851ProVal: 3.851 ± 0.065	0.454ProTrp: 0.454 ± 0.021	1.317ProTyr: 1.317 ± 0.037	0.0ProXaa: 0.0 ± 0.0
Gln	3.457GlnAla: 3.457 ± 0.062	0.334GlnCys: 0.334 ± 0.016	1.565GlnAsp: 1.565 ± 0.039	3.106GlnGlu: 3.106 ± 0.062	1.127GlnPhe: 1.127 ± 0.031	2.839GlnGly: 2.839 ± 0.054	0.656GlnHis: 0.656 ± 0.024	2.449GlnIle: 2.449 ± 0.05	2.62GlnLys: 2.62 ± 0.052	3.797GlnLeu: 3.797 ± 0.068	0.933GlnMet: 0.933 ± 0.026	1.437GlnAsn: 1.437 ± 0.037	1.3GlnPro: 1.3 ± 0.033	1.543GlnGln: 1.543 ± 0.04	1.731GlnArg: 1.731 ± 0.04	1.632GlnSer: 1.632 ± 0.047	1.604GlnThr: 1.604 ± 0.039	3.052GlnVal: 3.052 ± 0.065	0.335GlnTrp: 0.335 ± 0.018	0.961GlnTyr: 0.961 ± 0.032	0.0GlnXaa: 0.0 ± 0.0
Arg	3.486ArgAla: 3.486 ± 0.059	0.594ArgCys: 0.594 ± 0.027	2.128ArgAsp: 2.128 ± 0.047	4.021ArgGlu: 4.021 ± 0.074	1.992ArgPhe: 1.992 ± 0.05	3.263ArgGly: 3.263 ± 0.057	0.985ArgHis: 0.985 ± 0.032	3.446ArgIle: 3.446 ± 0.056	3.218ArgLys: 3.218 ± 0.055	5.387ArgLeu: 5.387 ± 0.087	1.293ArgMet: 1.293 ± 0.036	1.882ArgAsn: 1.882 ± 0.04	1.849ArgPro: 1.849 ± 0.046	2.2ArgGln: 2.2 ± 0.052	2.772ArgArg: 2.772 ± 0.058	2.265ArgSer: 2.265 ± 0.048	2.213ArgThr: 2.213 ± 0.048	3.636ArgVal: 3.636 ± 0.061	0.509ArgTrp: 0.509 ± 0.024	1.647ArgTyr: 1.647 ± 0.038	0.0ArgXaa: 0.0 ± 0.0
Ser	3.964SerAla: 3.964 ± 0.059	0.71SerCys: 0.71 ± 0.029	2.238SerAsp: 2.238 ± 0.053	3.044SerGlu: 3.044 ± 0.051	2.526SerPhe: 2.526 ± 0.054	4.617SerGly: 4.617 ± 0.069	1.006SerHis: 1.006 ± 0.036	3.715SerIle: 3.715 ± 0.062	3.151SerLys: 3.151 ± 0.056	6.079SerLeu: 6.079 ± 0.076	1.33SerMet: 1.33 ± 0.038	1.978SerAsn: 1.978 ± 0.052	2.424SerPro: 2.424 ± 0.051	1.884SerGln: 1.884 ± 0.048	2.905SerArg: 2.905 ± 0.056	3.394SerSer: 3.394 ± 0.067	2.722SerThr: 2.722 ± 0.057	3.484SerVal: 3.484 ± 0.063	0.632SerTrp: 0.632 ± 0.021	1.84SerTyr: 1.84 ± 0.048	0.0SerXaa: 0.0 ± 0.0
Thr	4.429ThrAla: 4.429 ± 0.066	0.564ThrCys: 0.564 ± 0.029	2.138ThrAsp: 2.138 ± 0.042	2.896ThrGlu: 2.896 ± 0.062	2.002ThrPhe: 2.002 ± 0.047	4.81ThrGly: 4.81 ± 0.068	0.897ThrHis: 0.897 ± 0.027	3.64ThrIle: 3.64 ± 0.067	2.73ThrLys: 2.73 ± 0.059	5.054ThrLeu: 5.054 ± 0.067	1.13ThrMet: 1.13 ± 0.035	1.718ThrAsn: 1.718 ± 0.042	2.473ThrPro: 2.473 ± 0.057	1.325ThrGln: 1.325 ± 0.038	2.22ThrArg: 2.22 ± 0.042	2.691ThrSer: 2.691 ± 0.054	2.658ThrThr: 2.658 ± 0.069	4.208ThrVal: 4.208 ± 0.068	0.469ThrTrp: 0.469 ± 0.023	1.53ThrTyr: 1.53 ± 0.037	0.0ThrXaa: 0.0 ± 0.0
Val	6.628ValAla: 6.628 ± 0.092	0.863ValCys: 0.863 ± 0.031	3.835ValAsp: 3.835 ± 0.065	5.482ValGlu: 5.482 ± 0.075	2.85ValPhe: 2.85 ± 0.055	5.278ValGly: 5.278 ± 0.081	1.238ValHis: 1.238 ± 0.033	5.374ValIle: 5.374 ± 0.079	4.918ValLys: 4.918 ± 0.071	8.067ValLeu: 8.067 ± 0.107	1.809ValMet: 1.809 ± 0.047	2.937ValAsn: 2.937 ± 0.061	3.129ValPro: 3.129 ± 0.06	2.588ValGln: 2.588 ± 0.056	3.433ValArg: 3.433 ± 0.062	4.151ValSer: 4.151 ± 0.06	4.046ValThr: 4.046 ± 0.071	6.002ValVal: 6.002 ± 0.092	0.65ValTrp: 0.65 ± 0.028	2.212ValTyr: 2.212 ± 0.042	0.0ValXaa: 0.0 ± 0.0
Trp	0.731TrpAla: 0.731 ± 0.029	0.115TrpCys: 0.115 ± 0.011	0.474TrpAsp: 0.474 ± 0.023	0.713TrpGlu: 0.713 ± 0.028	0.398TrpPhe: 0.398 ± 0.019	0.697TrpGly: 0.697 ± 0.029	0.215TrpHis: 0.215 ± 0.014	0.526TrpIle: 0.526 ± 0.023	0.53TrpLys: 0.53 ± 0.024	1.128TrpLeu: 1.128 ± 0.038	0.224TrpMet: 0.224 ± 0.014	0.369TrpAsn: 0.369 ± 0.02	0.388TrpPro: 0.388 ± 0.022	0.533TrpGln: 0.533 ± 0.023	0.537TrpArg: 0.537 ± 0.021	0.551TrpSer: 0.551 ± 0.024	0.415TrpThr: 0.415 ± 0.022	0.675TrpVal: 0.675 ± 0.025	0.117TrpTrp: 0.117 ± 0.012	0.306TrpTyr: 0.306 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.148TyrAla: 2.148 ± 0.045	0.465TyrCys: 0.465 ± 0.021	1.486TyrAsp: 1.486 ± 0.043	1.924TyrGlu: 1.924 ± 0.046	1.484TyrPhe: 1.484 ± 0.038	2.547TyrGly: 2.547 ± 0.045	0.63TyrHis: 0.63 ± 0.021	2.004TyrIle: 2.004 ± 0.041	1.81TyrLys: 1.81 ± 0.051	3.63TyrLeu: 3.63 ± 0.063	0.657TyrMet: 0.657 ± 0.026	1.341TyrAsn: 1.341 ± 0.031	1.331TyrPro: 1.331 ± 0.036	1.261TyrGln: 1.261 ± 0.039	1.822TyrArg: 1.822 ± 0.051	1.823TyrSer: 1.823 ± 0.044	1.489TyrThr: 1.489 ± 0.039	2.038TyrVal: 2.038 ± 0.042	0.342TyrTrp: 0.342 ± 0.018	1.169TyrTyr: 1.169 ± 0.033	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4397 proteins (1025325 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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