Coprococcus comes CAG:19

Taxonomy: cellular organisms; Bacteria; Terrabacteria group; Firmicutes; Clostridia; Eubacteriales; Lachnospiraceae; Coprococcus; environmental samples

Average proteome isoelectric point is 6.05

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 2198 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|R6LUV8|R6LUV8_9FIRM Uncharacterized protein OS=Coprococcus comes CAG:19 OX=1263070 GN=BN524_00659 PE=4 SV=1
MM1 pKa = 7.45YY2 pKa = 10.05YY3 pKa = 10.45VPDD6 pKa = 3.73GTKK9 pKa = 9.25EE10 pKa = 3.93CGFYY14 pKa = 10.51EE15 pKa = 4.77CKK17 pKa = 10.39KK18 pKa = 9.94CGNRR22 pKa = 11.84FLSLQTMNRR31 pKa = 11.84IPCPEE36 pKa = 4.29CEE38 pKa = 4.12AEE40 pKa = 3.72IDD42 pKa = 3.94YY43 pKa = 11.07EE44 pKa = 4.14IGPDD48 pKa = 3.46EE49 pKa = 4.88SMEE52 pKa = 4.46DD53 pKa = 3.56ALDD56 pKa = 3.73TAEE59 pKa = 4.86LLEE62 pKa = 4.61KK63 pKa = 10.33IIGEE67 pKa = 4.19EE68 pKa = 4.19EE69 pKa = 4.14VEE71 pKa = 4.85KK72 pKa = 10.52MDD74 pKa = 4.85GLLSLAITGGDD85 pKa = 4.04CNWII89 pKa = 3.74

Molecular weight: 10.02 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|R6LCM5|R6LCM5_9FIRM Penicillin-binding protein transpeptidase domain protein OS=Coprococcus comes CAG:19 OX=1263070 GN=BN524_02039 PE=4 SV=1
MM1 pKa = 7.41IPSMMTRR8 pKa = 11.84KK9 pKa = 7.11NTKK12 pKa = 8.29MRR14 pKa = 11.84MIPSMTTTKK23 pKa = 8.8NTRR26 pKa = 11.84MKK28 pKa = 9.41TIPSMTTTRR37 pKa = 11.84NTRR40 pKa = 11.84MKK42 pKa = 9.31TIPSMATTRR51 pKa = 11.84NTKK54 pKa = 9.29MKK56 pKa = 8.9MIPSMTMRR64 pKa = 11.84KK65 pKa = 5.9NTRR68 pKa = 11.84MKK70 pKa = 10.38TKK72 pKa = 7.7MTTRR76 pKa = 11.84SMMNN80 pKa = 3.0

Molecular weight: 9.42 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

2198

0

2198

690227

30

1706

314.0

35.14

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

7.603 ± 0.052

1.481 ± 0.019

5.517 ± 0.041

8.019 ± 0.067

3.956 ± 0.038

7.405 ± 0.052

1.779 ± 0.021

7.561 ± 0.048

7.249 ± 0.045

8.769 ± 0.054

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

3.315 ± 0.028

4.045 ± 0.025

3.303 ± 0.026

3.158 ± 0.028

4.227 ± 0.043

5.336 ± 0.039

5.361 ± 0.041

7.121 ± 0.038

0.828 ± 0.019

3.967 ± 0.032
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski