Amino acid dipepetide frequency for Rasamsonia emersonii CBS 393.64

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	9.646AlaAla: 9.646 ± 0.06	1.069AlaCys: 1.069 ± 0.014	4.354AlaAsp: 4.354 ± 0.036	5.373AlaGlu: 5.373 ± 0.048	2.946AlaPhe: 2.946 ± 0.026	5.848AlaGly: 5.848 ± 0.039	1.7AlaHis: 1.7 ± 0.019	4.112AlaIle: 4.112 ± 0.032	3.93AlaLys: 3.93 ± 0.036	7.539AlaLeu: 7.539 ± 0.049	1.771AlaMet: 1.771 ± 0.017	2.934AlaAsn: 2.934 ± 0.026	4.714AlaPro: 4.714 ± 0.042	3.397AlaGln: 3.397 ± 0.028	5.27AlaArg: 5.27 ± 0.034	7.355AlaSer: 7.355 ± 0.05	5.031AlaThr: 5.031 ± 0.037	5.473AlaVal: 5.473 ± 0.04	1.091AlaTrp: 1.091 ± 0.016	2.087AlaTyr: 2.087 ± 0.022	0.0AlaXaa: 0.0 ± 0.0
Cys	0.927CysAla: 0.927 ± 0.017	0.282CysCys: 0.282 ± 0.009	0.641CysAsp: 0.641 ± 0.013	0.567CysGlu: 0.567 ± 0.011	0.534CysPhe: 0.534 ± 0.011	0.895CysGly: 0.895 ± 0.018	0.379CysHis: 0.379 ± 0.009	0.682CysIle: 0.682 ± 0.012	0.46CysLys: 0.46 ± 0.011	1.335CysLeu: 1.335 ± 0.018	0.262CysMet: 0.262 ± 0.007	0.414CysAsn: 0.414 ± 0.009	0.733CysPro: 0.733 ± 0.014	0.494CysGln: 0.494 ± 0.011	0.878CysArg: 0.878 ± 0.013	1.015CysSer: 1.015 ± 0.017	0.678CysThr: 0.678 ± 0.012	0.797CysVal: 0.797 ± 0.013	0.223CysTrp: 0.223 ± 0.007	0.358CysTyr: 0.358 ± 0.01	0.0CysXaa: 0.0 ± 0.0
Asp	4.621AspAla: 4.621 ± 0.034	0.628AspCys: 0.628 ± 0.013	4.377AspAsp: 4.377 ± 0.053	4.501AspGlu: 4.501 ± 0.042	2.064AspPhe: 2.064 ± 0.022	4.032AspGly: 4.032 ± 0.038	1.241AspHis: 1.241 ± 0.015	2.887AspIle: 2.887 ± 0.027	2.253AspLys: 2.253 ± 0.025	4.996AspLeu: 4.996 ± 0.034	1.106AspMet: 1.106 ± 0.015	1.898AspAsn: 1.898 ± 0.022	3.56AspPro: 3.56 ± 0.028	1.896AspGln: 1.896 ± 0.021	3.426AspArg: 3.426 ± 0.035	4.203AspSer: 4.203 ± 0.036	2.774AspThr: 2.774 ± 0.029	3.712AspVal: 3.712 ± 0.03	0.867AspTrp: 0.867 ± 0.014	1.582AspTyr: 1.582 ± 0.017	0.0AspXaa: 0.0 ± 0.0
Glu	5.381GluAla: 5.381 ± 0.056	0.604GluCys: 0.604 ± 0.011	4.169GluAsp: 4.169 ± 0.037	6.132GluGlu: 6.132 ± 0.075	1.924GluPhe: 1.924 ± 0.022	3.701GluGly: 3.701 ± 0.029	1.338GluHis: 1.338 ± 0.014	3.118GluIle: 3.118 ± 0.026	3.994GluLys: 3.994 ± 0.035	5.116GluLeu: 5.116 ± 0.042	1.41GluMet: 1.41 ± 0.017	2.437GluAsn: 2.437 ± 0.025	2.858GluPro: 2.858 ± 0.032	2.627GluGln: 2.627 ± 0.025	4.327GluArg: 4.327 ± 0.038	4.537GluSer: 4.537 ± 0.038	3.589GluThr: 3.589 ± 0.03	3.447GluVal: 3.447 ± 0.032	0.869GluTrp: 0.869 ± 0.015	1.664GluTyr: 1.664 ± 0.021	0.0GluXaa: 0.0 ± 0.0
Phe	2.894PheAla: 2.894 ± 0.028	0.592PheCys: 0.592 ± 0.011	2.167PheAsp: 2.167 ± 0.022	2.037PheGlu: 2.037 ± 0.022	1.668PhePhe: 1.668 ± 0.025	2.55PheGly: 2.55 ± 0.033	0.923PheHis: 0.923 ± 0.015	1.703PheIle: 1.703 ± 0.023	1.351PheLys: 1.351 ± 0.018	3.595PheLeu: 3.595 ± 0.033	0.666PheMet: 0.666 ± 0.011	1.297PheAsn: 1.297 ± 0.017	2.025PhePro: 2.025 ± 0.019	1.352PheGln: 1.352 ± 0.02	2.066PheArg: 2.066 ± 0.02	2.995PheSer: 2.995 ± 0.027	1.947PheThr: 1.947 ± 0.022	2.367PheVal: 2.367 ± 0.023	0.611PheTrp: 0.611 ± 0.012	1.087PheTyr: 1.087 ± 0.017	0.0PheXaa: 0.0 ± 0.0
Gly	5.029GlyAla: 5.029 ± 0.039	0.88GlyCys: 0.88 ± 0.015	3.564GlyAsp: 3.564 ± 0.027	3.637GlyGlu: 3.637 ± 0.032	2.596GlyPhe: 2.596 ± 0.029	5.427GlyGly: 5.427 ± 0.043	1.639GlyHis: 1.639 ± 0.02	3.358GlyIle: 3.358 ± 0.029	3.29GlyLys: 3.29 ± 0.027	5.789GlyLeu: 5.789 ± 0.039	1.429GlyMet: 1.429 ± 0.019	2.452GlyAsn: 2.452 ± 0.027	3.439GlyPro: 3.439 ± 0.029	2.605GlyGln: 2.605 ± 0.021	4.414GlyArg: 4.414 ± 0.033	5.703GlySer: 5.703 ± 0.042	3.769GlyThr: 3.769 ± 0.029	4.285GlyVal: 4.285 ± 0.029	1.11GlyTrp: 1.11 ± 0.017	2.071GlyTyr: 2.071 ± 0.025	0.0GlyXaa: 0.0 ± 0.0
His	1.866HisAla: 1.866 ± 0.021	0.348HisCys: 0.348 ± 0.009	1.321HisAsp: 1.321 ± 0.02	1.318HisGlu: 1.318 ± 0.016	0.874HisPhe: 0.874 ± 0.014	1.706HisGly: 1.706 ± 0.022	0.907HisHis: 0.907 ± 0.017	1.136HisIle: 1.136 ± 0.016	0.81HisLys: 0.81 ± 0.016	2.253HisLeu: 2.253 ± 0.021	0.437HisMet: 0.437 ± 0.009	0.77HisAsn: 0.77 ± 0.012	1.751HisPro: 1.751 ± 0.024	0.954HisGln: 0.954 ± 0.015	1.708HisArg: 1.708 ± 0.024	1.829HisSer: 1.829 ± 0.021	1.17HisThr: 1.17 ± 0.018	1.491HisVal: 1.491 ± 0.017	0.334HisTrp: 0.334 ± 0.009	0.665HisTyr: 0.665 ± 0.013	0.0HisXaa: 0.0 ± 0.0
Ile	3.965IleAla: 3.965 ± 0.034	0.75IleCys: 0.75 ± 0.014	2.758IleAsp: 2.758 ± 0.023	2.766IleGlu: 2.766 ± 0.028	1.924IlePhe: 1.924 ± 0.024	2.925IleGly: 2.925 ± 0.034	1.2IleHis: 1.2 ± 0.017	2.419IleIle: 2.419 ± 0.032	2.03IleLys: 2.03 ± 0.025	4.537IleLeu: 4.537 ± 0.038	0.91IleMet: 0.91 ± 0.013	1.696IleAsn: 1.696 ± 0.019	3.091IlePro: 3.091 ± 0.027	1.884IleGln: 1.884 ± 0.018	2.966IleArg: 2.966 ± 0.027	3.761IleSer: 3.761 ± 0.032	2.6IleThr: 2.6 ± 0.025	3.091IleVal: 3.091 ± 0.028	0.69IleTrp: 0.69 ± 0.014	1.469IleTyr: 1.469 ± 0.018	0.0IleXaa: 0.0 ± 0.0
Lys	4.039LysAla: 4.039 ± 0.039	0.458LysCys: 0.458 ± 0.01	2.72LysAsp: 2.72 ± 0.028	3.587LysGlu: 3.587 ± 0.04	1.346LysPhe: 1.346 ± 0.017	2.816LysGly: 2.816 ± 0.026	1.006LysHis: 1.006 ± 0.014	2.246LysIle: 2.246 ± 0.025	3.406LysLys: 3.406 ± 0.051	3.908LysLeu: 3.908 ± 0.037	0.923LysMet: 0.923 ± 0.015	1.797LysAsn: 1.797 ± 0.021	2.712LysPro: 2.712 ± 0.028	1.914LysGln: 1.914 ± 0.022	3.512LysArg: 3.512 ± 0.033	3.292LysSer: 3.292 ± 0.029	2.724LysThr: 2.724 ± 0.028	2.664LysVal: 2.664 ± 0.023	0.603LysTrp: 0.603 ± 0.012	1.338LysTyr: 1.338 ± 0.018	0.0LysXaa: 0.0 ± 0.0
Leu	7.709LeuAla: 7.709 ± 0.051	1.245LeuCys: 1.245 ± 0.018	5.07LeuAsp: 5.07 ± 0.031	5.461LeuGlu: 5.461 ± 0.051	3.346LeuPhe: 3.346 ± 0.028	5.618LeuGly: 5.618 ± 0.036	2.214LeuHis: 2.214 ± 0.025	3.879LeuIle: 3.879 ± 0.035	4.095LeuLys: 4.095 ± 0.037	8.676LeuLeu: 8.676 ± 0.069	1.659LeuMet: 1.659 ± 0.021	3.048LeuAsn: 3.048 ± 0.028	5.669LeuPro: 5.669 ± 0.039	3.914LeuGln: 3.914 ± 0.037	6.23LeuArg: 6.23 ± 0.035	7.605LeuSer: 7.605 ± 0.048	4.795LeuThr: 4.795 ± 0.036	5.38LeuVal: 5.38 ± 0.038	1.171LeuTrp: 1.171 ± 0.016	2.414LeuTyr: 2.414 ± 0.026	0.0LeuXaa: 0.0 ± 0.0
Met	2.031MetAla: 2.031 ± 0.021	0.222MetCys: 0.222 ± 0.007	1.128MetAsp: 1.128 ± 0.017	1.213MetGlu: 1.213 ± 0.017	0.658MetPhe: 0.658 ± 0.013	1.282MetGly: 1.282 ± 0.019	0.429MetHis: 0.429 ± 0.01	0.916MetIle: 0.916 ± 0.013	0.898MetLys: 0.898 ± 0.014	1.702MetLeu: 1.702 ± 0.022	0.494MetMet: 0.494 ± 0.01	0.726MetAsn: 0.726 ± 0.014	1.13MetPro: 1.13 ± 0.017	0.798MetGln: 0.798 ± 0.014	1.206MetArg: 1.206 ± 0.016	1.686MetSer: 1.686 ± 0.018	1.214MetThr: 1.214 ± 0.017	1.167MetVal: 1.167 ± 0.017	0.232MetTrp: 0.232 ± 0.008	0.478MetTyr: 0.478 ± 0.01	0.0MetXaa: 0.0 ± 0.0
Asn	3.125AsnAla: 3.125 ± 0.027	0.452AsnCys: 0.452 ± 0.01	1.983AsnAsp: 1.983 ± 0.022	2.057AsnGlu: 2.057 ± 0.023	1.269AsnPhe: 1.269 ± 0.017	2.943AsnGly: 2.943 ± 0.027	0.854AsnHis: 0.854 ± 0.014	1.911AsnIle: 1.911 ± 0.025	1.513AsnLys: 1.513 ± 0.019	3.207AsnLeu: 3.207 ± 0.03	0.722AsnMet: 0.722 ± 0.014	1.833AsnAsn: 1.833 ± 0.033	2.536AsnPro: 2.536 ± 0.027	1.374AsnGln: 1.374 ± 0.019	2.093AsnArg: 2.093 ± 0.019	2.744AsnSer: 2.744 ± 0.025	2.021AsnThr: 2.021 ± 0.023	2.253AsnVal: 2.253 ± 0.025	0.52AsnTrp: 0.52 ± 0.01	1.058AsnTyr: 1.058 ± 0.019	0.0AsnXaa: 0.0 ± 0.0
Pro	5.557ProAla: 5.557 ± 0.05	0.583ProCys: 0.583 ± 0.012	3.436ProAsp: 3.436 ± 0.029	4.028ProGlu: 4.028 ± 0.035	2.1ProPhe: 2.1 ± 0.023	4.098ProGly: 4.098 ± 0.033	1.334ProHis: 1.334 ± 0.018	2.406ProIle: 2.406 ± 0.022	2.579ProLys: 2.579 ± 0.025	4.893ProLeu: 4.893 ± 0.029	0.959ProMet: 0.959 ± 0.015	2.205ProAsn: 2.205 ± 0.024	5.769ProPro: 5.769 ± 0.07	2.577ProGln: 2.577 ± 0.031	3.722ProArg: 3.722 ± 0.029	6.612ProSer: 6.612 ± 0.05	3.776ProThr: 3.776 ± 0.029	3.818ProVal: 3.818 ± 0.03	0.767ProTrp: 0.767 ± 0.014	1.583ProTyr: 1.583 ± 0.019	0.0ProXaa: 0.0 ± 0.0
Gln	3.484GlnAla: 3.484 ± 0.031	0.445GlnCys: 0.445 ± 0.009	2.07GlnAsp: 2.07 ± 0.02	2.597GlnGlu: 2.597 ± 0.027	1.262GlnPhe: 1.262 ± 0.016	2.372GlnGly: 2.372 ± 0.025	1.055GlnHis: 1.055 ± 0.017	1.829GlnIle: 1.829 ± 0.02	2.093GlnLys: 2.093 ± 0.025	3.51GlnLeu: 3.51 ± 0.032	0.845GlnMet: 0.845 ± 0.013	1.617GlnAsn: 1.617 ± 0.021	2.738GlnPro: 2.738 ± 0.032	3.072GlnGln: 3.072 ± 0.057	2.889GlnArg: 2.889 ± 0.028	3.295GlnSer: 3.295 ± 0.034	2.416GlnThr: 2.416 ± 0.024	2.157GlnVal: 2.157 ± 0.022	0.535GlnTrp: 0.535 ± 0.011	1.103GlnTyr: 1.103 ± 0.016	0.0GlnXaa: 0.0 ± 0.0
Arg	5.04ArgAla: 5.04 ± 0.033	0.84ArgCys: 0.84 ± 0.017	3.561ArgAsp: 3.561 ± 0.04	4.261ArgGlu: 4.261 ± 0.041	2.257ArgPhe: 2.257 ± 0.024	3.884ArgGly: 3.884 ± 0.037	1.742ArgHis: 1.742 ± 0.019	3.083ArgIle: 3.083 ± 0.025	3.675ArgLys: 3.675 ± 0.032	5.96ArgLeu: 5.96 ± 0.033	1.293ArgMet: 1.293 ± 0.017	2.37ArgAsn: 2.37 ± 0.023	3.96ArgPro: 3.96 ± 0.036	2.955ArgGln: 2.955 ± 0.028	6.088ArgArg: 6.088 ± 0.052	5.283ArgSer: 5.283 ± 0.043	3.376ArgThr: 3.376 ± 0.03	3.62ArgVal: 3.62 ± 0.028	1.005ArgTrp: 1.005 ± 0.017	1.781ArgTyr: 1.781 ± 0.02	0.0ArgXaa: 0.0 ± 0.0
Ser	6.843SerAla: 6.843 ± 0.044	0.972SerCys: 0.972 ± 0.014	4.297SerAsp: 4.297 ± 0.031	4.314SerGlu: 4.314 ± 0.038	2.977SerPhe: 2.977 ± 0.026	5.618SerGly: 5.618 ± 0.038	2.003SerHis: 2.003 ± 0.023	3.818SerIle: 3.818 ± 0.029	3.637SerLys: 3.637 ± 0.03	7.481SerLeu: 7.481 ± 0.048	1.578SerMet: 1.578 ± 0.018	3.088SerAsn: 3.088 ± 0.029	5.926SerPro: 5.926 ± 0.052	3.527SerGln: 3.527 ± 0.039	5.587SerArg: 5.587 ± 0.043	10.365SerSer: 10.365 ± 0.091	5.66SerThr: 5.66 ± 0.047	4.715SerVal: 4.715 ± 0.033	1.111SerTrp: 1.111 ± 0.017	2.049SerTyr: 2.049 ± 0.019	0.0SerXaa: 0.0 ± 0.0
Thr	5.294ThrAla: 5.294 ± 0.035	0.724ThrCys: 0.724 ± 0.014	2.766ThrAsp: 2.766 ± 0.025	3.109ThrGlu: 3.109 ± 0.03	2.073ThrPhe: 2.073 ± 0.025	4.096ThrGly: 4.096 ± 0.03	1.144ThrHis: 1.144 ± 0.016	2.811ThrIle: 2.811 ± 0.028	2.453ThrLys: 2.453 ± 0.023	4.947ThrLeu: 4.947 ± 0.037	1.076ThrMet: 1.076 ± 0.014	2.013ThrAsn: 2.013 ± 0.023	4.243ThrPro: 4.243 ± 0.036	2.013ThrGln: 2.013 ± 0.021	3.175ThrArg: 3.175 ± 0.029	5.343ThrSer: 5.343 ± 0.039	4.388ThrThr: 4.388 ± 0.054	3.819ThrVal: 3.819 ± 0.032	0.78ThrTrp: 0.78 ± 0.013	1.557ThrTyr: 1.557 ± 0.02	0.0ThrXaa: 0.0 ± 0.0
Val	5.053ValAla: 5.053 ± 0.034	0.857ValCys: 0.857 ± 0.014	3.801ValAsp: 3.801 ± 0.029	3.912ValGlu: 3.912 ± 0.033	2.409ValPhe: 2.409 ± 0.023	3.791ValGly: 3.791 ± 0.036	1.432ValHis: 1.432 ± 0.017	2.971ValIle: 2.971 ± 0.028	2.739ValLys: 2.739 ± 0.026	5.667ValLeu: 5.667 ± 0.04	1.179ValMet: 1.179 ± 0.016	2.196ValAsn: 2.196 ± 0.026	3.745ValPro: 3.745 ± 0.029	2.385ValGln: 2.385 ± 0.022	3.695ValArg: 3.695 ± 0.028	4.871ValSer: 4.871 ± 0.03	3.508ValThr: 3.508 ± 0.025	4.324ValVal: 4.324 ± 0.033	0.839ValTrp: 0.839 ± 0.014	1.716ValTyr: 1.716 ± 0.021	0.0ValXaa: 0.0 ± 0.0
Trp	1.051TrpAla: 1.051 ± 0.016	0.187TrpCys: 0.187 ± 0.007	0.838TrpAsp: 0.838 ± 0.015	0.822TrpGlu: 0.822 ± 0.014	0.511TrpPhe: 0.511 ± 0.01	0.843TrpGly: 0.843 ± 0.015	0.345TrpHis: 0.345 ± 0.009	0.761TrpIle: 0.761 ± 0.014	0.781TrpLys: 0.781 ± 0.013	1.369TrpLeu: 1.369 ± 0.021	0.332TrpMet: 0.332 ± 0.008	0.591TrpAsn: 0.591 ± 0.011	0.617TrpPro: 0.617 ± 0.013	0.563TrpGln: 0.563 ± 0.01	1.017TrpArg: 1.017 ± 0.015	1.018TrpSer: 1.018 ± 0.016	0.891TrpThr: 0.891 ± 0.013	0.832TrpVal: 0.832 ± 0.014	0.262TrpTrp: 0.262 ± 0.008	0.402TrpTyr: 0.402 ± 0.009	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.086TyrAla: 2.086 ± 0.021	0.416TyrCys: 0.416 ± 0.01	1.601TyrAsp: 1.601 ± 0.019	1.554TyrGlu: 1.554 ± 0.018	1.152TyrPhe: 1.152 ± 0.017	2.039TyrGly: 2.039 ± 0.025	0.762TyrHis: 0.762 ± 0.014	1.387TyrIle: 1.387 ± 0.019	1.026TyrLys: 1.026 ± 0.014	2.717TyrLeu: 2.717 ± 0.024	0.561TyrMet: 0.561 ± 0.011	1.088TyrAsn: 1.088 ± 0.016	1.585TyrPro: 1.585 ± 0.021	1.081TyrGln: 1.081 ± 0.014	1.766TyrArg: 1.766 ± 0.02	2.054TyrSer: 2.054 ± 0.022	1.497TyrThr: 1.497 ± 0.021	1.678TyrVal: 1.678 ± 0.023	0.412TyrTrp: 0.412 ± 0.009	0.984TyrTyr: 0.984 ± 0.018	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.001XaaPro: 0.001 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 9842 proteins (4794008 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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