Amino acid dipepetide frequency for Kanyawara virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.52AlaAla: 2.52 ± 1.486
2.52AlaCys: 2.52 ± 0.614
2.8AlaAsp: 2.8 ± 0.902
3.639AlaGlu: 3.639 ± 0.333
1.4AlaPhe: 1.4 ± 0.698
2.52AlaGly: 2.52 ± 1.101
1.4AlaHis: 1.4 ± 0.542
3.639AlaIle: 3.639 ± 0.742
1.68AlaLys: 1.68 ± 0.557
5.039AlaLeu: 5.039 ± 1.5
0.84AlaMet: 0.84 ± 0.796
3.359AlaAsn: 3.359 ± 1.837
1.12AlaPro: 1.12 ± 0.545
1.12AlaGln: 1.12 ± 0.556
1.4AlaArg: 1.4 ± 0.305
2.24AlaSer: 2.24 ± 0.763
3.639AlaThr: 3.639 ± 0.69
2.24AlaVal: 2.24 ± 0.463
0.28AlaTrp: 0.28 ± 0.159
2.8AlaTyr: 2.8 ± 1.075
0.0AlaXaa: 0.0 ± 0.0
Cys
0.28CysAla: 0.28 ± 0.159
0.56CysCys: 0.56 ± 0.319
0.28CysAsp: 0.28 ± 0.159
1.12CysGlu: 1.12 ± 0.641
1.4CysPhe: 1.4 ± 0.645
1.4CysGly: 1.4 ± 0.542
0.56CysHis: 0.56 ± 0.51
0.84CysIle: 0.84 ± 0.34
1.68CysLys: 1.68 ± 1.01
1.96CysLeu: 1.96 ± 0.692
0.28CysMet: 0.28 ± 0.609
1.96CysAsn: 1.96 ± 1.116
1.4CysPro: 1.4 ± 0.793
0.0CysGln: 0.0 ± 0.0
0.56CysArg: 0.56 ± 0.543
1.68CysSer: 1.68 ± 0.557
0.56CysThr: 0.56 ± 0.319
1.96CysVal: 1.96 ± 1.311
0.56CysTrp: 0.56 ± 0.319
0.56CysTyr: 0.56 ± 0.438
0.0CysXaa: 0.0 ± 0.0
Asp
3.639AspAla: 3.639 ± 0.813
1.12AspCys: 1.12 ± 0.877
3.919AspAsp: 3.919 ± 1.146
2.52AspGlu: 2.52 ± 1.095
1.96AspPhe: 1.96 ± 0.592
3.639AspGly: 3.639 ± 1.396
0.84AspHis: 0.84 ± 0.478
2.52AspIle: 2.52 ± 0.406
3.08AspLys: 3.08 ± 0.468
6.159AspLeu: 6.159 ± 1.314
1.68AspMet: 1.68 ± 0.526
2.8AspAsn: 2.8 ± 1.285
2.24AspPro: 2.24 ± 0.541
2.8AspGln: 2.8 ± 0.342
3.359AspArg: 3.359 ± 1.121
3.08AspSer: 3.08 ± 0.916
3.639AspThr: 3.639 ± 1.25
2.24AspVal: 2.24 ± 1.279
2.24AspTrp: 2.24 ± 0.813
3.359AspTyr: 3.359 ± 1.356
0.0AspXaa: 0.0 ± 0.0
Glu
2.24GluAla: 2.24 ± 0.463
0.84GluCys: 0.84 ± 0.34
3.359GluAsp: 3.359 ± 2.691
4.199GluGlu: 4.199 ± 1.62
2.24GluPhe: 2.24 ± 0.354
2.8GluGly: 2.8 ± 0.807
1.68GluHis: 1.68 ± 0.373
4.479GluIle: 4.479 ± 1.488
4.759GluLys: 4.759 ± 0.713
5.039GluLeu: 5.039 ± 1.707
1.4GluMet: 1.4 ± 0.305
1.96GluAsn: 1.96 ± 0.768
1.68GluPro: 1.68 ± 0.535
2.52GluGln: 2.52 ± 0.732
1.68GluArg: 1.68 ± 0.753
4.479GluSer: 4.479 ± 1.06
4.759GluThr: 4.759 ± 1.061
3.359GluVal: 3.359 ± 1.257
0.28GluTrp: 0.28 ± 0.41
1.96GluTyr: 1.96 ± 0.486
0.0GluXaa: 0.0 ± 0.0
Phe
1.4PheAla: 1.4 ± 0.797
0.84PheCys: 0.84 ± 0.392
3.639PheAsp: 3.639 ± 1.073
0.84PheGlu: 0.84 ± 0.478
1.4PhePhe: 1.4 ± 0.542
3.639PheGly: 3.639 ± 1.023
0.84PheHis: 0.84 ± 0.34
1.68PheIle: 1.68 ± 0.708
3.359PheLys: 3.359 ± 0.957
3.359PheLeu: 3.359 ± 0.828
0.56PheMet: 0.56 ± 0.353
2.52PheAsn: 2.52 ± 0.774
1.68PhePro: 1.68 ± 0.68
1.4PheGln: 1.4 ± 0.853
3.08PheArg: 3.08 ± 0.964
3.919PheSer: 3.919 ± 1.738
1.12PheThr: 1.12 ± 0.735
1.4PheVal: 1.4 ± 0.797
0.56PheTrp: 0.56 ± 0.32
1.12PheTyr: 1.12 ± 0.735
0.0PheXaa: 0.0 ± 0.0
Gly
1.12GlyAla: 1.12 ± 0.424
0.28GlyCys: 0.28 ± 0.159
1.96GlyAsp: 1.96 ± 0.526
2.52GlyGlu: 2.52 ± 1.176
2.24GlyPhe: 2.24 ± 0.463
3.919GlyGly: 3.919 ± 1.288
1.4GlyHis: 1.4 ± 0.641
5.599GlyIle: 5.599 ± 1.455
2.24GlyLys: 2.24 ± 0.603
8.119GlyLeu: 8.119 ± 1.011
0.84GlyMet: 0.84 ± 0.317
2.24GlyAsn: 2.24 ± 0.693
2.24GlyPro: 2.24 ± 1.276
2.24GlyGln: 2.24 ± 0.847
2.24GlyArg: 2.24 ± 0.603
6.719GlySer: 6.719 ± 1.581
3.639GlyThr: 3.639 ± 1.172
2.52GlyVal: 2.52 ± 1.262
0.84GlyTrp: 0.84 ± 0.478
1.4GlyTyr: 1.4 ± 0.542
0.0GlyXaa: 0.0 ± 0.0
His
1.96HisAla: 1.96 ± 1.333
0.0HisCys: 0.0 ± 0.0
1.96HisAsp: 1.96 ± 1.311
1.96HisGlu: 1.96 ± 0.819
2.24HisPhe: 2.24 ± 0.975
0.56HisGly: 0.56 ± 0.353
0.84HisHis: 0.84 ± 1.125
2.24HisIle: 2.24 ± 0.966
1.4HisLys: 1.4 ± 0.305
1.68HisLeu: 1.68 ± 0.708
0.56HisMet: 0.56 ± 0.32
1.68HisAsn: 1.68 ± 0.614
1.68HisPro: 1.68 ± 0.373
1.4HisGln: 1.4 ± 0.305
1.68HisArg: 1.68 ± 0.708
1.96HisSer: 1.96 ± 0.906
1.4HisThr: 1.4 ± 1.052
1.4HisVal: 1.4 ± 0.579
1.12HisTrp: 1.12 ± 0.638
1.12HisTyr: 1.12 ± 0.424
0.0HisXaa: 0.0 ± 0.0
Ile
3.359IleAla: 3.359 ± 0.642
2.24IleCys: 2.24 ± 0.693
4.479IleAsp: 4.479 ± 1.323
4.759IleGlu: 4.759 ± 1.091
1.68IlePhe: 1.68 ± 0.62
3.08IleGly: 3.08 ± 0.922
3.919IleHis: 3.919 ± 1.585
6.159IleIle: 6.159 ± 1.565
6.159IleLys: 6.159 ± 1.543
7.559IleLeu: 7.559 ± 1.313
1.4IleMet: 1.4 ± 0.797
3.359IleAsn: 3.359 ± 0.478
3.919IlePro: 3.919 ± 1.104
2.8IleGln: 2.8 ± 1.099
4.759IleArg: 4.759 ± 0.768
5.599IleSer: 5.599 ± 1.106
5.599IleThr: 5.599 ± 2.288
2.52IleVal: 2.52 ± 0.391
0.0IleTrp: 0.0 ± 0.0
1.96IleTyr: 1.96 ± 0.825
0.0IleXaa: 0.0 ± 0.0
Lys
2.52LysAla: 2.52 ± 0.66
1.68LysCys: 1.68 ± 0.678
5.319LysAsp: 5.319 ± 1.404
3.919LysGlu: 3.919 ± 1.661
1.4LysPhe: 1.4 ± 0.868
3.919LysGly: 3.919 ± 1.25
1.4LysHis: 1.4 ± 1.052
5.039LysIle: 5.039 ± 0.902
5.879LysLys: 5.879 ± 1.322
7.839LysLeu: 7.839 ± 1.5
1.96LysMet: 1.96 ± 1.597
2.8LysAsn: 2.8 ± 0.897
2.52LysPro: 2.52 ± 0.647
1.68LysGln: 1.68 ± 0.614
3.639LysArg: 3.639 ± 0.656
2.8LysSer: 2.8 ± 0.408
3.919LysThr: 3.919 ± 1.253
3.359LysVal: 3.359 ± 1.205
1.96LysTrp: 1.96 ± 0.608
0.84LysTyr: 0.84 ± 0.478
0.0LysXaa: 0.0 ± 0.0
Leu
3.08LeuAla: 3.08 ± 0.681
1.4LeuCys: 1.4 ± 0.994
5.879LeuAsp: 5.879 ± 1.997
6.999LeuGlu: 6.999 ± 1.28
3.639LeuPhe: 3.639 ± 1.373
6.159LeuGly: 6.159 ± 0.874
2.8LeuHis: 2.8 ± 1.044
7.839LeuIle: 7.839 ± 2.301
5.319LeuLys: 5.319 ± 2.025
9.239LeuLeu: 9.239 ± 2.384
3.359LeuMet: 3.359 ± 1.049
6.999LeuAsn: 6.999 ± 3.311
3.08LeuPro: 3.08 ± 1.563
3.919LeuGln: 3.919 ± 1.35
6.159LeuArg: 6.159 ± 2.115
10.078LeuSer: 10.078 ± 0.534
8.679LeuThr: 8.679 ± 0.86
3.639LeuVal: 3.639 ± 1.033
1.12LeuTrp: 1.12 ± 0.313
3.919LeuTyr: 3.919 ± 1.254
0.0LeuXaa: 0.0 ± 0.0
Met
1.68MetAla: 1.68 ± 0.479
0.84MetCys: 0.84 ± 0.478
0.84MetAsp: 0.84 ± 0.478
1.12MetGlu: 1.12 ± 0.949
1.68MetPhe: 1.68 ± 0.526
1.4MetGly: 1.4 ± 0.645
0.56MetHis: 0.56 ± 0.32
2.24MetIle: 2.24 ± 0.354
1.4MetLys: 1.4 ± 0.641
2.24MetLeu: 2.24 ± 0.859
0.56MetMet: 0.56 ± 0.319
2.24MetAsn: 2.24 ± 0.847
0.0MetPro: 0.0 ± 0.0
0.56MetGln: 0.56 ± 0.819
0.84MetArg: 0.84 ± 0.363
2.8MetSer: 2.8 ± 1.174
0.56MetThr: 0.56 ± 0.319
0.28MetVal: 0.28 ± 0.159
0.84MetTrp: 0.84 ± 0.34
0.28MetTyr: 0.28 ± 0.159
0.0MetXaa: 0.0 ± 0.0
Asn
2.24AsnAla: 2.24 ± 0.619
1.12AsnCys: 1.12 ± 0.883
2.8AsnAsp: 2.8 ± 0.704
1.4AsnGlu: 1.4 ± 0.486
1.68AsnPhe: 1.68 ± 0.678
1.68AsnGly: 1.68 ± 0.784
1.12AsnHis: 1.12 ± 0.437
3.639AsnIle: 3.639 ± 1.185
3.919AsnLys: 3.919 ± 0.851
8.679AsnLeu: 8.679 ± 1.462
1.4AsnMet: 1.4 ± 0.994
3.919AsnAsn: 3.919 ± 1.023
3.08AsnPro: 3.08 ± 0.63
2.52AsnGln: 2.52 ± 0.436
1.12AsnArg: 1.12 ± 0.479
5.319AsnSer: 5.319 ± 1.836
1.68AsnThr: 1.68 ± 0.441
3.639AsnVal: 3.639 ± 0.835
0.84AsnTrp: 0.84 ± 0.392
2.52AsnTyr: 2.52 ± 0.82
0.0AsnXaa: 0.0 ± 0.0
Pro
1.68ProAla: 1.68 ± 0.373
0.28ProCys: 0.28 ± 0.375
2.52ProAsp: 2.52 ± 0.857
2.8ProGlu: 2.8 ± 0.979
1.96ProPhe: 1.96 ± 0.417
1.4ProGly: 1.4 ± 0.587
1.12ProHis: 1.12 ± 0.424
2.8ProIle: 2.8 ± 0.903
2.8ProLys: 2.8 ± 0.797
3.639ProLeu: 3.639 ± 1.251
0.84ProMet: 0.84 ± 0.392
1.68ProAsn: 1.68 ± 0.538
1.96ProPro: 1.96 ± 0.417
2.8ProGln: 2.8 ± 0.777
1.96ProArg: 1.96 ± 0.822
3.359ProSer: 3.359 ± 1.76
2.52ProThr: 2.52 ± 0.857
2.52ProVal: 2.52 ± 0.771
0.56ProTrp: 0.56 ± 0.353
1.68ProTyr: 1.68 ± 1.146
0.0ProXaa: 0.0 ± 0.0
Gln
1.68GlnAla: 1.68 ± 0.585
0.56GlnCys: 0.56 ± 0.32
0.84GlnAsp: 0.84 ± 0.478
1.12GlnGlu: 1.12 ± 0.437
1.4GlnPhe: 1.4 ± 0.305
1.4GlnGly: 1.4 ± 0.641
1.12GlnHis: 1.12 ± 0.706
3.639GlnIle: 3.639 ± 1.53
2.24GlnLys: 2.24 ± 0.608
3.359GlnLeu: 3.359 ± 1.091
0.84GlnMet: 0.84 ± 0.363
2.52GlnAsn: 2.52 ± 1.285
1.96GlnPro: 1.96 ± 1.18
0.28GlnGln: 0.28 ± 0.159
1.96GlnArg: 1.96 ± 1.726
3.359GlnSer: 3.359 ± 0.924
1.68GlnThr: 1.68 ± 0.683
3.359GlnVal: 3.359 ± 1.183
0.56GlnTrp: 0.56 ± 0.32
2.24GlnTyr: 2.24 ± 1.479
0.0GlnXaa: 0.0 ± 0.0
Arg
3.639ArgAla: 3.639 ± 0.886
1.12ArgCys: 1.12 ± 0.424
3.359ArgAsp: 3.359 ± 1.199
3.919ArgGlu: 3.919 ± 0.895
3.359ArgPhe: 3.359 ± 1.455
2.24ArgGly: 2.24 ± 0.725
1.12ArgHis: 1.12 ± 0.638
3.919ArgIle: 3.919 ± 1.177
2.52ArgLys: 2.52 ± 1.116
3.639ArgLeu: 3.639 ± 1.226
1.4ArgMet: 1.4 ± 0.513
3.359ArgAsn: 3.359 ± 0.967
2.24ArgPro: 2.24 ± 0.631
1.12ArgGln: 1.12 ± 0.479
1.68ArgArg: 1.68 ± 0.441
3.359ArgSer: 3.359 ± 1.375
3.639ArgThr: 3.639 ± 1.267
1.96ArgVal: 1.96 ± 0.592
1.12ArgTrp: 1.12 ± 1.049
1.68ArgTyr: 1.68 ± 0.779
0.0ArgXaa: 0.0 ± 0.0
Ser
5.319SerAla: 5.319 ± 2.591
0.84SerCys: 0.84 ± 0.52
4.479SerAsp: 4.479 ± 0.655
4.479SerGlu: 4.479 ± 0.812
1.96SerPhe: 1.96 ± 0.486
3.359SerGly: 3.359 ± 0.952
2.24SerHis: 2.24 ± 0.693
5.599SerIle: 5.599 ± 1.875
4.759SerLys: 4.759 ± 1.685
8.399SerLeu: 8.399 ± 2.162
1.96SerMet: 1.96 ± 0.959
1.68SerAsn: 1.68 ± 1.06
2.8SerPro: 2.8 ± 0.777
3.359SerGln: 3.359 ± 1.798
5.039SerArg: 5.039 ± 1.503
10.918SerSer: 10.918 ± 1.941
5.879SerThr: 5.879 ± 2.049
5.039SerVal: 5.039 ± 0.861
2.8SerTrp: 2.8 ± 0.807
2.52SerTyr: 2.52 ± 1.46
0.0SerXaa: 0.0 ± 0.0
Thr
1.68ThrAla: 1.68 ± 0.585
1.4ThrCys: 1.4 ± 0.793
3.359ThrAsp: 3.359 ± 0.471
3.639ThrGlu: 3.639 ± 1.566
2.24ThrPhe: 2.24 ± 0.956
4.199ThrGly: 4.199 ± 0.744
1.96ThrHis: 1.96 ± 0.692
3.919ThrIle: 3.919 ± 1.012
3.359ThrLys: 3.359 ± 1.877
7.279ThrLeu: 7.279 ± 2.411
0.56ThrMet: 0.56 ± 0.319
3.359ThrAsn: 3.359 ± 1.529
2.52ThrPro: 2.52 ± 1.066
2.52ThrGln: 2.52 ± 0.502
3.639ThrArg: 3.639 ± 0.903
3.919ThrSer: 3.919 ± 1.738
4.479ThrThr: 4.479 ± 1.441
3.359ThrVal: 3.359 ± 1.826
1.96ThrTrp: 1.96 ± 0.608
3.639ThrTyr: 3.639 ± 0.799
0.0ThrXaa: 0.0 ± 0.0
Val
2.8ValAla: 2.8 ± 0.979
1.12ValCys: 1.12 ± 0.427
2.24ValAsp: 2.24 ± 0.631
3.08ValGlu: 3.08 ± 0.603
1.96ValPhe: 1.96 ± 0.486
4.199ValGly: 4.199 ± 0.957
2.52ValHis: 2.52 ± 1.586
4.759ValIle: 4.759 ± 1.267
3.359ValLys: 3.359 ± 0.981
5.039ValLeu: 5.039 ± 0.89
1.12ValMet: 1.12 ± 0.424
2.8ValAsn: 2.8 ± 0.548
1.96ValPro: 1.96 ± 0.819
1.12ValGln: 1.12 ± 0.556
0.84ValArg: 0.84 ± 0.478
3.639ValSer: 3.639 ± 0.78
3.08ValThr: 3.08 ± 0.821
2.8ValVal: 2.8 ± 1.632
0.84ValTrp: 0.84 ± 0.52
1.12ValTyr: 1.12 ± 1.135
0.0ValXaa: 0.0 ± 0.0
Trp
0.84TrpAla: 0.84 ± 0.43
0.0TrpCys: 0.0 ± 0.0
1.4TrpAsp: 1.4 ± 0.612
0.28TrpGlu: 0.28 ± 0.159
1.4TrpPhe: 1.4 ± 0.645
1.12TrpGly: 1.12 ± 0.638
0.28TrpHis: 0.28 ± 0.159
2.52TrpIle: 2.52 ± 1.276
1.68TrpLys: 1.68 ± 0.678
0.84TrpLeu: 0.84 ± 0.34
0.56TrpMet: 0.56 ± 0.319
1.12TrpAsn: 1.12 ± 0.641
0.56TrpPro: 0.56 ± 0.319
0.56TrpGln: 0.56 ± 0.543
1.4TrpArg: 1.4 ± 0.542
1.4TrpSer: 1.4 ± 0.486
1.4TrpThr: 1.4 ± 0.305
1.4TrpVal: 1.4 ± 0.587
0.28TrpTrp: 0.28 ± 0.159
0.28TrpTyr: 0.28 ± 0.375
0.0TrpXaa: 0.0 ± 0.0
Tyr
2.52TyrAla: 2.52 ± 0.57
0.84TyrCys: 0.84 ± 0.34
1.4TyrAsp: 1.4 ± 0.542
1.4TyrGlu: 1.4 ± 1.052
1.12TyrPhe: 1.12 ± 0.641
1.68TyrGly: 1.68 ± 0.557
1.12TyrHis: 1.12 ± 0.437
2.24TyrIle: 2.24 ± 0.412
3.08TyrLys: 3.08 ± 0.63
4.199TyrLeu: 4.199 ± 1.233
0.56TyrMet: 0.56 ± 0.353
1.96TyrAsn: 1.96 ± 1.116
2.24TyrPro: 2.24 ± 0.675
1.4TyrGln: 1.4 ± 0.793
3.359TyrArg: 3.359 ± 1.499
2.8TyrSer: 2.8 ± 1.026
1.12TyrThr: 1.12 ± 0.427
1.4TyrVal: 1.4 ± 0.852
0.56TyrTrp: 0.56 ± 0.543
1.4TyrTyr: 1.4 ± 0.522
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3573 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski