Amino acid dipepetide frequency for Anaerostipes hadrus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	5.726AlaAla: 5.726 ± 0.104	0.903AlaCys: 0.903 ± 0.041	3.915AlaAsp: 3.915 ± 0.072	4.067AlaGlu: 4.067 ± 0.086	2.938AlaPhe: 2.938 ± 0.076	5.378AlaGly: 5.378 ± 0.092	1.048AlaHis: 1.048 ± 0.038	5.182AlaIle: 5.182 ± 0.092	5.787AlaLys: 5.787 ± 0.11	5.868AlaLeu: 5.868 ± 0.101	2.43AlaMet: 2.43 ± 0.058	2.475AlaAsn: 2.475 ± 0.061	1.671AlaPro: 1.671 ± 0.05	2.173AlaGln: 2.173 ± 0.051	2.516AlaArg: 2.516 ± 0.054	3.625AlaSer: 3.625 ± 0.067	3.458AlaThr: 3.458 ± 0.08	5.612AlaVal: 5.612 ± 0.101	0.431AlaTrp: 0.431 ± 0.025	2.607AlaTyr: 2.607 ± 0.057	0.0AlaXaa: 0.0 ± 0.0
Cys	0.909CysAla: 0.909 ± 0.035	0.257CysCys: 0.257 ± 0.017	0.84CysAsp: 0.84 ± 0.033	0.893CysGlu: 0.893 ± 0.033	0.607CysPhe: 0.607 ± 0.032	1.34CysGly: 1.34 ± 0.044	0.281CysHis: 0.281 ± 0.018	1.11CysIle: 1.11 ± 0.039	1.017CysLys: 1.017 ± 0.039	1.098CysLeu: 1.098 ± 0.034	0.49CysMet: 0.49 ± 0.025	0.546CysAsn: 0.546 ± 0.031	0.569CysPro: 0.569 ± 0.03	0.388CysGln: 0.388 ± 0.023	0.497CysArg: 0.497 ± 0.024	0.816CysSer: 0.816 ± 0.029	0.697CysThr: 0.697 ± 0.029	0.949CysVal: 0.949 ± 0.034	0.097CysTrp: 0.097 ± 0.011	0.563CysTyr: 0.563 ± 0.026	0.0CysXaa: 0.0 ± 0.0
Asp	3.779AspAla: 3.779 ± 0.069	0.763AspCys: 0.763 ± 0.028	3.202AspAsp: 3.202 ± 0.077	4.843AspGlu: 4.843 ± 0.07	2.676AspPhe: 2.676 ± 0.066	4.162AspGly: 4.162 ± 0.082	1.351AspHis: 1.351 ± 0.046	4.906AspIle: 4.906 ± 0.085	4.214AspLys: 4.214 ± 0.078	4.883AspLeu: 4.883 ± 0.075	1.995AspMet: 1.995 ± 0.053	2.151AspAsn: 2.151 ± 0.056	1.784AspPro: 1.784 ± 0.053	2.117AspGln: 2.117 ± 0.056	2.028AspArg: 2.028 ± 0.056	2.84AspSer: 2.84 ± 0.067	2.97AspThr: 2.97 ± 0.061	3.913AspVal: 3.913 ± 0.075	0.49AspTrp: 0.49 ± 0.025	2.922AspTyr: 2.922 ± 0.059	0.0AspXaa: 0.0 ± 0.0
Glu	4.985GluAla: 4.985 ± 0.086	0.84GluCys: 0.84 ± 0.03	4.709GluAsp: 4.709 ± 0.08	7.657GluGlu: 7.657 ± 0.12	2.691GluPhe: 2.691 ± 0.061	4.253GluGly: 4.253 ± 0.08	1.478GluHis: 1.478 ± 0.042	6.166GluIle: 6.166 ± 0.099	6.859GluLys: 6.859 ± 0.115	6.338GluLeu: 6.338 ± 0.097	2.496GluMet: 2.496 ± 0.063	4.098GluAsn: 4.098 ± 0.073	1.609GluPro: 1.609 ± 0.048	2.81GluGln: 2.81 ± 0.062	3.006GluArg: 3.006 ± 0.066	3.297GluSer: 3.297 ± 0.07	3.641GluThr: 3.641 ± 0.059	4.554GluVal: 4.554 ± 0.086	0.617GluTrp: 0.617 ± 0.027	3.113GluTyr: 3.113 ± 0.063	0.0GluXaa: 0.0 ± 0.0
Phe	2.847PheAla: 2.847 ± 0.062	0.643PheCys: 0.643 ± 0.027	2.686PheAsp: 2.686 ± 0.064	2.811PheGlu: 2.811 ± 0.058	1.835PhePhe: 1.835 ± 0.056	3.14PheGly: 3.14 ± 0.072	0.912PheHis: 0.912 ± 0.035	3.039PheIle: 3.039 ± 0.072	2.5PheLys: 2.5 ± 0.058	4.034PheLeu: 4.034 ± 0.077	1.209PheMet: 1.209 ± 0.04	1.51PheAsn: 1.51 ± 0.044	1.233PhePro: 1.233 ± 0.038	1.244PheGln: 1.244 ± 0.038	1.353PheArg: 1.353 ± 0.044	2.592PheSer: 2.592 ± 0.058	2.274PheThr: 2.274 ± 0.058	2.968PheVal: 2.968 ± 0.062	0.355PheTrp: 0.355 ± 0.021	1.717PheTyr: 1.717 ± 0.041	0.0PheXaa: 0.0 ± 0.0
Gly	4.64GlyAla: 4.64 ± 0.096	1.244GlyCys: 1.244 ± 0.046	3.357GlyAsp: 3.357 ± 0.067	4.176GlyGlu: 4.176 ± 0.071	3.106GlyPhe: 3.106 ± 0.071	4.471GlyGly: 4.471 ± 0.087	1.276GlyHis: 1.276 ± 0.039	6.434GlyIle: 6.434 ± 0.107	6.017GlyLys: 6.017 ± 0.101	5.39GlyLeu: 5.39 ± 0.097	2.396GlyMet: 2.396 ± 0.059	3.262GlyAsn: 3.262 ± 0.074	1.222GlyPro: 1.222 ± 0.041	1.957GlyGln: 1.957 ± 0.05	2.667GlyArg: 2.667 ± 0.062	3.829GlySer: 3.829 ± 0.07	4.099GlyThr: 4.099 ± 0.081	4.832GlyVal: 4.832 ± 0.075	0.595GlyTrp: 0.595 ± 0.031	3.313GlyTyr: 3.313 ± 0.061	0.0GlyXaa: 0.0 ± 0.0
His	1.073HisAla: 1.073 ± 0.033	0.297HisCys: 0.297 ± 0.02	0.943HisAsp: 0.943 ± 0.04	1.186HisGlu: 1.186 ± 0.038	0.885HisPhe: 0.885 ± 0.032	1.52HisGly: 1.52 ± 0.047	0.424HisHis: 0.424 ± 0.033	1.483HisIle: 1.483 ± 0.051	1.25HisLys: 1.25 ± 0.038	1.628HisLeu: 1.628 ± 0.045	0.647HisMet: 0.647 ± 0.031	0.751HisAsn: 0.751 ± 0.031	0.894HisPro: 0.894 ± 0.035	0.648HisGln: 0.648 ± 0.026	0.722HisArg: 0.722 ± 0.034	0.929HisSer: 0.929 ± 0.027	1.037HisThr: 1.037 ± 0.04	1.14HisVal: 1.14 ± 0.033	0.182HisTrp: 0.182 ± 0.017	0.808HisTyr: 0.808 ± 0.03	0.0HisXaa: 0.0 ± 0.0
Ile	5.874IleAla: 5.874 ± 0.093	1.388IleCys: 1.388 ± 0.041	4.58IleAsp: 4.58 ± 0.085	5.554IleGlu: 5.554 ± 0.089	3.234IlePhe: 3.234 ± 0.08	5.444IleGly: 5.444 ± 0.096	1.609IleHis: 1.609 ± 0.049	5.891IleIle: 5.891 ± 0.093	6.06IleLys: 6.06 ± 0.098	7.491IleLeu: 7.491 ± 0.127	2.262IleMet: 2.262 ± 0.061	3.258IleAsn: 3.258 ± 0.062	3.189IlePro: 3.189 ± 0.06	2.49IleGln: 2.49 ± 0.062	3.415IleArg: 3.415 ± 0.078	5.367IleSer: 5.367 ± 0.091	4.602IleThr: 4.602 ± 0.081	5.261IleVal: 5.261 ± 0.09	0.565IleTrp: 0.565 ± 0.028	3.221IleTyr: 3.221 ± 0.068	0.0IleXaa: 0.0 ± 0.0
Lys	5.501LysAla: 5.501 ± 0.085	0.743LysCys: 0.743 ± 0.032	5.395LysAsp: 5.395 ± 0.092	8.524LysGlu: 8.524 ± 0.126	2.319LysPhe: 2.319 ± 0.054	4.697LysGly: 4.697 ± 0.092	1.358LysHis: 1.358 ± 0.039	6.714LysIle: 6.714 ± 0.106	9.033LysLys: 9.033 ± 0.157	5.982LysLeu: 5.982 ± 0.085	2.682LysMet: 2.682 ± 0.057	4.5LysAsn: 4.5 ± 0.077	2.102LysPro: 2.102 ± 0.052	3.229LysGln: 3.229 ± 0.075	3.418LysArg: 3.418 ± 0.063	3.724LysSer: 3.724 ± 0.071	4.476LysThr: 4.476 ± 0.083	5.586LysVal: 5.586 ± 0.107	0.61LysTrp: 0.61 ± 0.032	3.474LysTyr: 3.474 ± 0.067	0.0LysXaa: 0.0 ± 0.0
Leu	5.784LeuAla: 5.784 ± 0.092	1.357LeuCys: 1.357 ± 0.039	5.087LeuAsp: 5.087 ± 0.088	5.924LeuGlu: 5.924 ± 0.099	3.444LeuPhe: 3.444 ± 0.085	5.66LeuGly: 5.66 ± 0.096	1.468LeuHis: 1.468 ± 0.043	6.368LeuIle: 6.368 ± 0.112	7.362LeuLys: 7.362 ± 0.104	7.392LeuLeu: 7.392 ± 0.124	2.672LeuMet: 2.672 ± 0.061	3.99LeuAsn: 3.99 ± 0.069	3.103LeuPro: 3.103 ± 0.058	2.455LeuGln: 2.455 ± 0.057	3.308LeuArg: 3.308 ± 0.061	5.873LeuSer: 5.873 ± 0.086	4.743LeuThr: 4.743 ± 0.092	5.171LeuVal: 5.171 ± 0.094	0.677LeuTrp: 0.677 ± 0.032	3.236LeuTyr: 3.236 ± 0.073	0.0LeuXaa: 0.0 ± 0.0
Met	2.389MetAla: 2.389 ± 0.059	0.356MetCys: 0.356 ± 0.02	1.938MetAsp: 1.938 ± 0.049	2.677MetGlu: 2.677 ± 0.061	1.148MetPhe: 1.148 ± 0.042	2.043MetGly: 2.043 ± 0.052	0.485MetHis: 0.485 ± 0.024	3.04MetIle: 3.04 ± 0.066	3.184MetLys: 3.184 ± 0.062	2.68MetLeu: 2.68 ± 0.059	1.126MetMet: 1.126 ± 0.04	1.642MetAsn: 1.642 ± 0.043	1.034MetPro: 1.034 ± 0.034	1.107MetGln: 1.107 ± 0.037	1.148MetArg: 1.148 ± 0.038	1.75MetSer: 1.75 ± 0.045	1.767MetThr: 1.767 ± 0.049	1.867MetVal: 1.867 ± 0.046	0.207MetTrp: 0.207 ± 0.015	0.983MetTyr: 0.983 ± 0.037	0.0MetXaa: 0.0 ± 0.0
Asn	2.898AsnAla: 2.898 ± 0.064	0.598AsnCys: 0.598 ± 0.033	2.415AsnAsp: 2.415 ± 0.051	3.313AsnGlu: 3.313 ± 0.066	1.603AsnPhe: 1.603 ± 0.054	3.459AsnGly: 3.459 ± 0.07	0.925AsnHis: 0.925 ± 0.037	3.787AsnIle: 3.787 ± 0.07	3.529AsnLys: 3.529 ± 0.064	3.862AsnLeu: 3.862 ± 0.071	1.47AsnMet: 1.47 ± 0.047	1.94AsnAsn: 1.94 ± 0.055	1.857AsnPro: 1.857 ± 0.047	1.702AsnGln: 1.702 ± 0.045	1.765AsnArg: 1.765 ± 0.051	2.156AsnSer: 2.156 ± 0.055	2.359AsnThr: 2.359 ± 0.061	2.937AsnVal: 2.937 ± 0.055	0.389AsnTrp: 0.389 ± 0.021	1.889AsnTyr: 1.889 ± 0.047	0.0AsnXaa: 0.0 ± 0.0
Pro	2.005ProAla: 2.005 ± 0.056	0.414ProCys: 0.414 ± 0.023	1.978ProAsp: 1.978 ± 0.056	2.811ProGlu: 2.811 ± 0.069	1.422ProPhe: 1.422 ± 0.039	1.981ProGly: 1.981 ± 0.054	0.554ProHis: 0.554 ± 0.027	2.241ProIle: 2.241 ± 0.054	2.141ProLys: 2.141 ± 0.057	2.491ProLeu: 2.491 ± 0.063	0.909ProMet: 0.909 ± 0.035	1.271ProAsn: 1.271 ± 0.037	0.553ProPro: 0.553 ± 0.027	0.995ProGln: 0.995 ± 0.031	0.946ProArg: 0.946 ± 0.034	1.613ProSer: 1.613 ± 0.043	1.523ProThr: 1.523 ± 0.047	2.568ProVal: 2.568 ± 0.054	0.307ProTrp: 0.307 ± 0.021	1.373ProTyr: 1.373 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	2.15GlnAla: 2.15 ± 0.051	0.4GlnCys: 0.4 ± 0.023	1.484GlnAsp: 1.484 ± 0.04	2.545GlnGlu: 2.545 ± 0.063	1.275GlnPhe: 1.275 ± 0.039	1.963GlnGly: 1.963 ± 0.067	0.454GlnHis: 0.454 ± 0.031	3.058GlnIle: 3.058 ± 0.071	3.226GlnLys: 3.226 ± 0.07	2.866GlnLeu: 2.866 ± 0.058	1.327GlnMet: 1.327 ± 0.042	1.56GlnAsn: 1.56 ± 0.043	0.813GlnPro: 0.813 ± 0.031	1.235GlnGln: 1.235 ± 0.05	1.395GlnArg: 1.395 ± 0.046	1.651GlnSer: 1.651 ± 0.051	1.871GlnThr: 1.871 ± 0.055	2.042GlnVal: 2.042 ± 0.051	0.336GlnTrp: 0.336 ± 0.023	1.459GlnTyr: 1.459 ± 0.041	0.0GlnXaa: 0.0 ± 0.0
Arg	2.181ArgAla: 2.181 ± 0.052	0.528ArgCys: 0.528 ± 0.026	2.027ArgAsp: 2.027 ± 0.053	3.124ArgGlu: 3.124 ± 0.069	1.738ArgPhe: 1.738 ± 0.047	2.13ArgGly: 2.13 ± 0.051	0.688ArgHis: 0.688 ± 0.033	3.22ArgIle: 3.22 ± 0.073	3.556ArgLys: 3.556 ± 0.066	3.255ArgLeu: 3.255 ± 0.065	1.35ArgMet: 1.35 ± 0.034	1.932ArgAsn: 1.932 ± 0.05	1.154ArgPro: 1.154 ± 0.04	1.42ArgGln: 1.42 ± 0.044	1.858ArgArg: 1.858 ± 0.062	2.145ArgSer: 2.145 ± 0.053	1.915ArgThr: 1.915 ± 0.056	2.303ArgVal: 2.303 ± 0.057	0.337ArgTrp: 0.337 ± 0.021	1.733ArgTyr: 1.733 ± 0.053	0.0ArgXaa: 0.0 ± 0.0
Ser	3.544SerAla: 3.544 ± 0.068	0.718SerCys: 0.718 ± 0.031	3.247SerAsp: 3.247 ± 0.066	3.687SerGlu: 3.687 ± 0.065	2.529SerPhe: 2.529 ± 0.057	4.546SerGly: 4.546 ± 0.078	0.945SerHis: 0.945 ± 0.033	4.278SerIle: 4.278 ± 0.082	4.527SerLys: 4.527 ± 0.086	4.725SerLeu: 4.725 ± 0.085	1.972SerMet: 1.972 ± 0.053	2.468SerAsn: 2.468 ± 0.055	1.513SerPro: 1.513 ± 0.046	1.649SerGln: 1.649 ± 0.05	2.129SerArg: 2.129 ± 0.048	3.462SerSer: 3.462 ± 0.092	2.832SerThr: 2.832 ± 0.066	4.172SerVal: 4.172 ± 0.081	0.468SerTrp: 0.468 ± 0.025	2.442SerTyr: 2.442 ± 0.069	0.0SerXaa: 0.0 ± 0.0
Thr	3.969ThrAla: 3.969 ± 0.083	0.643ThrCys: 0.643 ± 0.028	3.022ThrAsp: 3.022 ± 0.066	3.326ThrGlu: 3.326 ± 0.063	2.282ThrPhe: 2.282 ± 0.053	4.363ThrGly: 4.363 ± 0.076	0.876ThrHis: 0.876 ± 0.032	4.574ThrIle: 4.574 ± 0.078	4.271ThrLys: 4.271 ± 0.084	4.714ThrLeu: 4.714 ± 0.077	1.483ThrMet: 1.483 ± 0.041	2.172ThrAsn: 2.172 ± 0.064	1.973ThrPro: 1.973 ± 0.058	1.591ThrGln: 1.591 ± 0.047	1.904ThrArg: 1.904 ± 0.048	3.123ThrSer: 3.123 ± 0.07	3.241ThrThr: 3.241 ± 0.091	4.119ThrVal: 4.119 ± 0.093	0.451ThrTrp: 0.451 ± 0.027	2.258ThrTyr: 2.258 ± 0.063	0.0ThrXaa: 0.0 ± 0.0
Val	4.64ValAla: 4.64 ± 0.092	1.153ValCys: 1.153 ± 0.035	3.916ValAsp: 3.916 ± 0.072	4.436ValGlu: 4.436 ± 0.088	2.869ValPhe: 2.869 ± 0.068	4.264ValGly: 4.264 ± 0.087	1.129ValHis: 1.129 ± 0.035	5.61ValIle: 5.61 ± 0.087	5.524ValLys: 5.524 ± 0.086	6.075ValLeu: 6.075 ± 0.09	2.121ValMet: 2.121 ± 0.057	2.986ValAsn: 2.986 ± 0.066	2.287ValPro: 2.287 ± 0.058	1.904ValGln: 1.904 ± 0.047	2.453ValArg: 2.453 ± 0.055	4.396ValSer: 4.396 ± 0.084	4.239ValThr: 4.239 ± 0.086	4.844ValVal: 4.844 ± 0.088	0.516ValTrp: 0.516 ± 0.024	2.613ValTyr: 2.613 ± 0.05	0.0ValXaa: 0.0 ± 0.0
Trp	0.459TrpAla: 0.459 ± 0.027	0.116TrpCys: 0.116 ± 0.013	0.495TrpAsp: 0.495 ± 0.028	0.541TrpGlu: 0.541 ± 0.027	0.393TrpPhe: 0.393 ± 0.023	0.568TrpGly: 0.568 ± 0.026	0.156TrpHis: 0.156 ± 0.014	0.679TrpIle: 0.679 ± 0.033	0.794TrpLys: 0.794 ± 0.033	0.664TrpLeu: 0.664 ± 0.03	0.342TrpMet: 0.342 ± 0.02	0.548TrpAsn: 0.548 ± 0.028	0.143TrpPro: 0.143 ± 0.014	0.271TrpGln: 0.271 ± 0.018	0.276TrpArg: 0.276 ± 0.02	0.42TrpSer: 0.42 ± 0.024	0.361TrpThr: 0.361 ± 0.023	0.415TrpVal: 0.415 ± 0.025	0.081TrpTrp: 0.081 ± 0.009	0.348TrpTyr: 0.348 ± 0.021	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.457TyrAla: 2.457 ± 0.054	0.605TyrCys: 0.605 ± 0.028	2.756TyrAsp: 2.756 ± 0.061	3.122TyrGlu: 3.122 ± 0.063	1.909TyrPhe: 1.909 ± 0.052	2.899TyrGly: 2.899 ± 0.07	1.027TyrHis: 1.027 ± 0.038	2.976TyrIle: 2.976 ± 0.067	3.214TyrLys: 3.214 ± 0.065	3.64TyrLeu: 3.64 ± 0.072	1.191TyrMet: 1.191 ± 0.043	1.793TyrAsn: 1.793 ± 0.054	1.393TyrPro: 1.393 ± 0.044	1.726TyrGln: 1.726 ± 0.046	1.791TyrArg: 1.791 ± 0.054	2.246TyrSer: 2.246 ± 0.063	2.246TyrThr: 2.246 ± 0.06	2.724TyrVal: 2.724 ± 0.063	0.358TyrTrp: 0.358 ± 0.024	1.948TyrTyr: 1.948 ± 0.047	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2771 proteins (812062 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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