Amino acid dipepetide frequency for Changjiang crawfish virus 1

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
4.811AlaAla: 4.811 ± 0.335
2.221AlaCys: 2.221 ± 0.683
1.85AlaAsp: 1.85 ± 0.819
1.48AlaGlu: 1.48 ± 0.883
4.071AlaPhe: 4.071 ± 0.505
3.701AlaGly: 3.701 ± 2.279
2.591AlaHis: 2.591 ± 0.263
2.961AlaIle: 2.961 ± 0.798
2.591AlaLys: 2.591 ± 0.904
4.071AlaLeu: 4.071 ± 0.136
1.11AlaMet: 1.11 ± 0.662
4.071AlaAsn: 4.071 ± 0.136
3.701AlaPro: 3.701 ± 1.639
3.701AlaGln: 3.701 ± 0.284
2.961AlaArg: 2.961 ± 0.157
6.662AlaSer: 6.662 ± 2.437
6.662AlaThr: 6.662 ± 1.796
3.701AlaVal: 3.701 ± 0.357
1.11AlaTrp: 1.11 ± 0.021
2.591AlaTyr: 2.591 ± 0.904
0.0AlaXaa: 0.0 ± 0.0
Cys
1.48CysAla: 1.48 ± 0.242
0.74CysCys: 0.74 ± 0.84
0.74CysAsp: 0.74 ± 0.441
1.11CysGlu: 1.11 ± 0.662
0.74CysPhe: 0.74 ± 0.2
1.11CysGly: 1.11 ± 0.021
0.74CysHis: 0.74 ± 0.2
1.48CysIle: 1.48 ± 0.883
0.37CysLys: 0.37 ± 0.221
1.11CysLeu: 1.11 ± 0.662
1.85CysMet: 1.85 ± 0.463
0.74CysAsn: 0.74 ± 0.2
2.221CysPro: 2.221 ± 0.042
1.11CysGln: 1.11 ± 0.662
0.37CysArg: 0.37 ± 0.221
1.48CysSer: 1.48 ± 0.242
0.37CysThr: 0.37 ± 0.42
1.85CysVal: 1.85 ± 1.104
0.74CysTrp: 0.74 ± 0.2
0.37CysTyr: 0.37 ± 0.42
0.0CysXaa: 0.0 ± 0.0
Asp
2.221AspAla: 2.221 ± 0.599
2.221AspCys: 2.221 ± 0.042
4.441AspAsp: 4.441 ± 0.085
5.181AspGlu: 5.181 ± 0.115
4.071AspPhe: 4.071 ± 0.136
2.591AspGly: 2.591 ± 0.904
1.85AspHis: 1.85 ± 0.463
2.961AspIle: 2.961 ± 1.125
2.221AspLys: 2.221 ± 1.324
2.221AspLeu: 2.221 ± 1.88
2.591AspMet: 2.591 ± 0.263
0.37AspAsn: 0.37 ± 0.221
4.441AspPro: 4.441 ± 2.479
1.11AspGln: 1.11 ± 0.662
1.85AspArg: 1.85 ± 1.104
2.591AspSer: 2.591 ± 0.904
1.85AspThr: 1.85 ± 0.463
7.772AspVal: 7.772 ± 0.79
1.48AspTrp: 1.48 ± 0.883
1.85AspTyr: 1.85 ± 0.463
0.0AspXaa: 0.0 ± 0.0
Glu
2.961GluAla: 2.961 ± 0.157
1.48GluCys: 1.48 ± 0.883
3.701GluAsp: 3.701 ± 1.566
4.811GluGlu: 4.811 ± 0.976
2.961GluPhe: 2.961 ± 1.125
2.591GluGly: 2.591 ± 0.263
0.74GluHis: 0.74 ± 0.441
5.181GluIle: 5.181 ± 1.397
2.591GluLys: 2.591 ± 0.904
8.142GluLeu: 8.142 ± 1.01
2.961GluMet: 2.961 ± 0.157
1.11GluAsn: 1.11 ± 0.021
3.331GluPro: 3.331 ± 0.064
1.85GluGln: 1.85 ± 1.104
2.961GluArg: 2.961 ± 1.125
3.701GluSer: 3.701 ± 0.357
3.331GluThr: 3.331 ± 1.218
4.811GluVal: 4.811 ± 0.947
1.11GluTrp: 1.11 ± 0.021
2.221GluTyr: 2.221 ± 1.24
0.0GluXaa: 0.0 ± 0.0
Phe
2.221PheAla: 2.221 ± 0.683
0.0PheCys: 0.0 ± 0.0
2.591PheAsp: 2.591 ± 0.378
3.331PheGlu: 3.331 ± 0.577
3.331PhePhe: 3.331 ± 0.064
4.071PheGly: 4.071 ± 0.136
1.85PheHis: 1.85 ± 0.463
2.591PheIle: 2.591 ± 0.263
2.591PheLys: 2.591 ± 0.263
3.331PheLeu: 3.331 ± 0.064
1.85PheMet: 1.85 ± 0.178
2.221PheAsn: 2.221 ± 0.683
2.961PhePro: 2.961 ± 0.484
2.221PheGln: 2.221 ± 0.042
2.591PheArg: 2.591 ± 0.378
2.961PheSer: 2.961 ± 0.157
3.701PheThr: 3.701 ± 0.998
1.85PheVal: 1.85 ± 0.463
1.11PheTrp: 1.11 ± 0.021
1.85PheTyr: 1.85 ± 0.819
0.0PheXaa: 0.0 ± 0.0
Gly
3.701GlyAla: 3.701 ± 0.998
1.48GlyCys: 1.48 ± 0.242
2.591GlyAsp: 2.591 ± 0.378
2.221GlyGlu: 2.221 ± 0.599
4.811GlyPhe: 4.811 ± 0.976
4.071GlyGly: 4.071 ± 0.136
0.37GlyHis: 0.37 ± 0.42
2.961GlyIle: 2.961 ± 0.157
3.331GlyLys: 3.331 ± 0.705
3.331GlyLeu: 3.331 ± 0.705
2.961GlyMet: 2.961 ± 1.021
3.331GlyAsn: 3.331 ± 0.064
2.961GlyPro: 2.961 ± 0.798
1.11GlyGln: 1.11 ± 0.021
2.961GlyArg: 2.961 ± 0.484
4.441GlySer: 4.441 ± 0.085
2.591GlyThr: 2.591 ± 1.019
5.551GlyVal: 5.551 ± 1.388
1.85GlyTrp: 1.85 ± 0.178
2.591GlyTyr: 2.591 ± 0.378
0.0GlyXaa: 0.0 ± 0.0
His
2.591HisAla: 2.591 ± 0.263
0.74HisCys: 0.74 ± 0.441
2.221HisAsp: 2.221 ± 0.042
0.74HisGlu: 0.74 ± 0.441
0.74HisPhe: 0.74 ± 0.84
1.85HisGly: 1.85 ± 0.463
1.11HisHis: 1.11 ± 0.662
2.221HisIle: 2.221 ± 0.683
1.48HisLys: 1.48 ± 0.399
1.11HisLeu: 1.11 ± 0.662
0.0HisMet: 0.0 ± 0.0
0.74HisAsn: 0.74 ± 0.2
1.48HisPro: 1.48 ± 0.883
0.37HisGln: 0.37 ± 0.42
1.85HisArg: 1.85 ± 0.463
1.85HisSer: 1.85 ± 0.178
1.48HisThr: 1.48 ± 0.883
2.221HisVal: 2.221 ± 0.042
0.37HisTrp: 0.37 ± 0.221
0.74HisTyr: 0.74 ± 0.2
0.0HisXaa: 0.0 ± 0.0
Ile
5.181IleAla: 5.181 ± 2.679
0.37IleCys: 0.37 ± 0.221
3.331IleAsp: 3.331 ± 0.705
2.961IleGlu: 2.961 ± 0.484
1.85IlePhe: 1.85 ± 1.104
2.961IleGly: 2.961 ± 0.157
1.48IleHis: 1.48 ± 0.242
1.85IleIle: 1.85 ± 0.178
2.961IleLys: 2.961 ± 1.125
3.331IleLeu: 3.331 ± 1.346
1.48IleMet: 1.48 ± 0.883
2.591IleAsn: 2.591 ± 0.378
3.331IlePro: 3.331 ± 0.064
1.85IleGln: 1.85 ± 1.104
2.221IleArg: 2.221 ± 0.042
3.701IleSer: 3.701 ± 1.639
2.961IleThr: 2.961 ± 0.798
2.961IleVal: 2.961 ± 1.439
0.0IleTrp: 0.0 ± 0.0
0.74IleTyr: 0.74 ± 0.441
0.0IleXaa: 0.0 ± 0.0
Lys
3.331LysAla: 3.331 ± 1.987
1.11LysCys: 1.11 ± 0.662
4.441LysAsp: 4.441 ± 0.726
5.181LysGlu: 5.181 ± 3.09
1.48LysPhe: 1.48 ± 0.883
3.331LysGly: 3.331 ± 1.346
2.221LysHis: 2.221 ± 1.324
1.11LysIle: 1.11 ± 0.662
2.961LysLys: 2.961 ± 1.766
3.701LysLeu: 3.701 ± 0.357
1.48LysMet: 1.48 ± 0.242
1.85LysAsn: 1.85 ± 0.463
2.961LysPro: 2.961 ± 2.08
2.591LysGln: 2.591 ± 0.263
4.441LysArg: 4.441 ± 1.367
2.961LysSer: 2.961 ± 1.125
2.961LysThr: 2.961 ± 1.125
1.85LysVal: 1.85 ± 0.463
1.48LysTrp: 1.48 ± 0.883
2.591LysTyr: 2.591 ± 0.904
0.0LysXaa: 0.0 ± 0.0
Leu
8.512LeuAla: 8.512 ± 1.231
1.85LeuCys: 1.85 ± 1.104
5.551LeuAsp: 5.551 ± 1.176
5.922LeuGlu: 5.922 ± 0.327
1.85LeuPhe: 1.85 ± 0.463
5.181LeuGly: 5.181 ± 0.526
1.11LeuHis: 1.11 ± 0.021
2.961LeuIle: 2.961 ± 0.157
4.441LeuLys: 4.441 ± 2.008
3.701LeuLeu: 3.701 ± 0.284
1.85LeuMet: 1.85 ± 1.104
3.701LeuAsn: 3.701 ± 0.925
7.032LeuPro: 7.032 ± 0.989
2.591LeuGln: 2.591 ± 0.378
4.441LeuArg: 4.441 ± 0.556
4.441LeuSer: 4.441 ± 1.197
4.441LeuThr: 4.441 ± 0.726
2.591LeuVal: 2.591 ± 0.263
1.11LeuTrp: 1.11 ± 0.62
1.48LeuTyr: 1.48 ± 0.242
0.0LeuXaa: 0.0 ± 0.0
Met
1.85MetAla: 1.85 ± 0.178
0.74MetCys: 0.74 ± 0.441
1.11MetAsp: 1.11 ± 0.662
2.221MetGlu: 2.221 ± 0.683
1.11MetPhe: 1.11 ± 0.021
2.961MetGly: 2.961 ± 0.484
1.48MetHis: 1.48 ± 0.399
0.74MetIle: 0.74 ± 0.441
2.591MetLys: 2.591 ± 0.904
2.221MetLeu: 2.221 ± 0.683
0.74MetMet: 0.74 ± 0.441
2.961MetAsn: 2.961 ± 0.484
0.0MetPro: 0.0 ± 0.0
0.74MetGln: 0.74 ± 0.441
1.11MetArg: 1.11 ± 0.662
4.071MetSer: 4.071 ± 1.146
4.071MetThr: 4.071 ± 0.777
0.74MetVal: 0.74 ± 0.2
0.0MetTrp: 0.0 ± 0.0
1.11MetTyr: 1.11 ± 0.662
0.0MetXaa: 0.0 ± 0.0
Asn
2.221AsnAla: 2.221 ± 0.599
0.74AsnCys: 0.74 ± 0.2
2.221AsnAsp: 2.221 ± 0.042
1.85AsnGlu: 1.85 ± 0.178
1.85AsnPhe: 1.85 ± 0.178
3.331AsnGly: 3.331 ± 0.064
1.11AsnHis: 1.11 ± 0.662
2.221AsnIle: 2.221 ± 0.042
2.591AsnLys: 2.591 ± 1.019
5.181AsnLeu: 5.181 ± 0.526
1.48AsnMet: 1.48 ± 0.242
1.85AsnAsn: 1.85 ± 0.819
2.591AsnPro: 2.591 ± 0.378
1.11AsnGln: 1.11 ± 0.021
2.591AsnArg: 2.591 ± 1.019
2.961AsnSer: 2.961 ± 1.439
4.441AsnThr: 4.441 ± 1.367
3.331AsnVal: 3.331 ± 0.064
0.37AsnTrp: 0.37 ± 0.221
0.37AsnTyr: 0.37 ± 0.42
0.0AsnXaa: 0.0 ± 0.0
Pro
1.48ProAla: 1.48 ± 0.399
0.37ProCys: 0.37 ± 0.42
3.701ProAsp: 3.701 ± 1.566
5.922ProGlu: 5.922 ± 0.955
1.11ProPhe: 1.11 ± 1.261
2.961ProGly: 2.961 ± 0.157
2.221ProHis: 2.221 ± 0.042
4.071ProIle: 4.071 ± 0.136
3.331ProLys: 3.331 ± 0.705
4.811ProLeu: 4.811 ± 1.617
1.85ProMet: 1.85 ± 0.463
1.48ProAsn: 1.48 ± 0.883
2.591ProPro: 2.591 ± 0.904
2.961ProGln: 2.961 ± 2.08
0.74ProArg: 0.74 ± 0.84
3.701ProSer: 3.701 ± 0.357
4.071ProThr: 4.071 ± 2.059
5.922ProVal: 5.922 ± 1.596
1.11ProTrp: 1.11 ± 0.021
2.221ProTyr: 2.221 ± 1.24
0.0ProXaa: 0.0 ± 0.0
Gln
1.48GlnAla: 1.48 ± 0.883
0.37GlnCys: 0.37 ± 0.221
1.11GlnAsp: 1.11 ± 0.021
2.591GlnGlu: 2.591 ± 1.019
0.74GlnPhe: 0.74 ± 0.441
1.85GlnGly: 1.85 ± 0.819
0.74GlnHis: 0.74 ± 0.2
0.74GlnIle: 0.74 ± 0.84
1.85GlnLys: 1.85 ± 0.463
2.961GlnLeu: 2.961 ± 1.125
1.11GlnMet: 1.11 ± 0.021
2.221GlnAsn: 2.221 ± 0.599
1.85GlnPro: 1.85 ± 0.463
1.11GlnGln: 1.11 ± 0.021
3.701GlnArg: 3.701 ± 0.925
2.961GlnSer: 2.961 ± 1.439
4.071GlnThr: 4.071 ± 0.136
1.85GlnVal: 1.85 ± 0.178
0.37GlnTrp: 0.37 ± 0.42
1.85GlnTyr: 1.85 ± 0.178
0.0GlnXaa: 0.0 ± 0.0
Arg
4.811ArgAla: 4.811 ± 0.335
0.37ArgCys: 0.37 ± 0.221
1.48ArgAsp: 1.48 ± 0.883
2.591ArgGlu: 2.591 ± 1.545
4.441ArgPhe: 4.441 ± 1.197
1.48ArgGly: 1.48 ± 0.399
1.11ArgHis: 1.11 ± 0.021
2.961ArgIle: 2.961 ± 0.798
2.221ArgLys: 2.221 ± 0.683
2.221ArgLeu: 2.221 ± 0.042
2.591ArgMet: 2.591 ± 0.904
1.85ArgAsn: 1.85 ± 1.104
1.48ArgPro: 1.48 ± 0.242
1.11ArgGln: 1.11 ± 0.62
4.071ArgArg: 4.071 ± 1.787
2.221ArgSer: 2.221 ± 1.24
4.071ArgThr: 4.071 ± 0.505
4.811ArgVal: 4.811 ± 0.306
1.11ArgTrp: 1.11 ± 0.021
2.221ArgTyr: 2.221 ± 0.042
0.0ArgXaa: 0.0 ± 0.0
Ser
7.402SerAla: 7.402 ± 3.918
2.221SerCys: 2.221 ± 0.683
3.701SerAsp: 3.701 ± 0.284
3.331SerGlu: 3.331 ± 1.218
2.961SerPhe: 2.961 ± 0.157
2.961SerGly: 2.961 ± 1.439
0.37SerHis: 0.37 ± 0.42
3.701SerIle: 3.701 ± 0.284
4.071SerLys: 4.071 ± 1.787
6.292SerLeu: 6.292 ± 1.189
1.85SerMet: 1.85 ± 0.178
2.591SerAsn: 2.591 ± 1.019
2.961SerPro: 2.961 ± 2.721
3.701SerGln: 3.701 ± 0.998
1.85SerArg: 1.85 ± 1.46
8.512SerSer: 8.512 ± 0.692
5.181SerThr: 5.181 ± 0.115
4.811SerVal: 4.811 ± 0.335
0.74SerTrp: 0.74 ± 0.441
2.591SerTyr: 2.591 ± 1.66
0.0SerXaa: 0.0 ± 0.0
Thr
3.331ThrAla: 3.331 ± 0.064
0.37ThrCys: 0.37 ± 0.42
2.591ThrAsp: 2.591 ± 0.263
3.701ThrGlu: 3.701 ± 0.357
4.811ThrPhe: 4.811 ± 0.335
3.331ThrGly: 3.331 ± 0.064
0.74ThrHis: 0.74 ± 0.2
2.591ThrIle: 2.591 ± 1.66
5.181ThrLys: 5.181 ± 2.449
7.772ThrLeu: 7.772 ± 0.79
1.85ThrMet: 1.85 ± 0.463
4.811ThrAsn: 4.811 ± 2.899
4.811ThrPro: 4.811 ± 1.617
2.591ThrGln: 2.591 ± 1.019
1.85ThrArg: 1.85 ± 0.178
5.551ThrSer: 5.551 ± 1.817
6.292ThrThr: 6.292 ± 3.298
4.441ThrVal: 4.441 ± 1.838
1.11ThrTrp: 1.11 ± 0.021
1.85ThrTyr: 1.85 ± 0.178
0.0ThrXaa: 0.0 ± 0.0
Val
4.071ValAla: 4.071 ± 0.777
1.85ValCys: 1.85 ± 0.463
4.071ValAsp: 4.071 ± 0.777
3.701ValGlu: 3.701 ± 1.566
3.331ValPhe: 3.331 ± 0.577
5.551ValGly: 5.551 ± 0.106
2.221ValHis: 2.221 ± 0.683
1.85ValIle: 1.85 ± 0.463
4.071ValLys: 4.071 ± 2.428
7.032ValLeu: 7.032 ± 1.63
1.85ValMet: 1.85 ± 0.406
3.701ValAsn: 3.701 ± 0.998
4.811ValPro: 4.811 ± 0.976
1.85ValGln: 1.85 ± 0.178
3.331ValArg: 3.331 ± 1.346
3.701ValSer: 3.701 ± 0.357
4.441ValThr: 4.441 ± 2.479
5.922ValVal: 5.922 ± 2.237
1.48ValTrp: 1.48 ± 0.242
2.591ValTyr: 2.591 ± 1.66
0.0ValXaa: 0.0 ± 0.0
Trp
1.11TrpAla: 1.11 ± 0.021
0.0TrpCys: 0.0 ± 0.0
0.74TrpAsp: 0.74 ± 0.441
1.48TrpGlu: 1.48 ± 0.883
1.11TrpPhe: 1.11 ± 0.662
0.74TrpGly: 0.74 ± 0.2
0.74TrpHis: 0.74 ± 0.2
1.11TrpIle: 1.11 ± 0.662
1.85TrpLys: 1.85 ± 0.819
1.11TrpLeu: 1.11 ± 0.021
0.74TrpMet: 0.74 ± 0.441
0.74TrpAsn: 0.74 ± 0.2
0.0TrpPro: 0.0 ± 0.0
0.74TrpGln: 0.74 ± 0.2
1.48TrpArg: 1.48 ± 0.399
0.37TrpSer: 0.37 ± 0.42
0.74TrpThr: 0.74 ± 0.2
1.11TrpVal: 1.11 ± 0.662
0.0TrpTrp: 0.0 ± 0.0
1.11TrpTyr: 1.11 ± 0.021
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.85TyrAla: 1.85 ± 0.178
1.48TyrCys: 1.48 ± 1.04
3.701TyrAsp: 3.701 ± 0.284
2.221TyrGlu: 2.221 ± 0.599
1.85TyrPhe: 1.85 ± 0.463
2.591TyrGly: 2.591 ± 0.263
1.11TyrHis: 1.11 ± 0.662
1.85TyrIle: 1.85 ± 1.104
0.74TyrLys: 0.74 ± 0.441
1.11TyrLeu: 1.11 ± 0.62
0.0TyrMet: 0.0 ± 0.0
1.48TyrAsn: 1.48 ± 0.399
1.11TyrPro: 1.11 ± 0.021
1.11TyrGln: 1.11 ± 0.021
1.85TyrArg: 1.85 ± 0.819
2.961TyrSer: 2.961 ± 1.439
1.85TyrThr: 1.85 ± 1.46
3.701TyrVal: 3.701 ± 0.998
0.37TyrTrp: 0.37 ± 0.42
1.85TyrTyr: 1.85 ± 0.178
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 2 proteins (2703 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski