Amino acid dipepetide frequency for Apricot latent virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
5.637AlaAla: 5.637 ± 3.029
1.989AlaCys: 1.989 ± 0.833
2.321AlaAsp: 2.321 ± 0.858
2.653AlaGlu: 2.653 ± 1.364
2.321AlaPhe: 2.321 ± 0.859
2.321AlaGly: 2.321 ± 0.823
1.658AlaHis: 1.658 ± 0.589
4.973AlaIle: 4.973 ± 1.319
4.973AlaLys: 4.973 ± 1.796
5.637AlaLeu: 5.637 ± 0.687
1.658AlaMet: 1.658 ± 0.853
3.647AlaAsn: 3.647 ± 1.923
1.658AlaPro: 1.658 ± 1.198
1.658AlaGln: 1.658 ± 2.256
2.653AlaArg: 2.653 ± 0.441
5.637AlaSer: 5.637 ± 1.34
5.968AlaThr: 5.968 ± 4.673
5.637AlaVal: 5.637 ± 2.123
0.332AlaTrp: 0.332 ± 0.797
1.658AlaTyr: 1.658 ± 0.555
0.0AlaXaa: 0.0 ± 0.0
Cys
1.658CysAla: 1.658 ± 0.834
0.332CysCys: 0.332 ± 0.988
1.326CysAsp: 1.326 ± 0.682
0.995CysGlu: 0.995 ± 0.512
1.658CysPhe: 1.658 ± 0.853
1.326CysGly: 1.326 ± 0.795
0.0CysHis: 0.0 ± 0.0
1.326CysIle: 1.326 ± 0.682
0.995CysLys: 0.995 ± 0.512
2.653CysLeu: 2.653 ± 2.377
0.663CysMet: 0.663 ± 0.341
1.326CysAsn: 1.326 ± 0.682
0.663CysPro: 0.663 ± 0.341
1.658CysGln: 1.658 ± 0.589
0.332CysArg: 0.332 ± 0.171
2.653CysSer: 2.653 ± 0.915
2.321CysThr: 2.321 ± 2.672
1.326CysVal: 1.326 ± 0.682
0.0CysTrp: 0.0 ± 0.0
0.332CysTyr: 0.332 ± 0.171
0.0CysXaa: 0.0 ± 0.0
Asp
2.321AspAla: 2.321 ± 0.859
1.658AspCys: 1.658 ± 0.589
2.984AspAsp: 2.984 ± 1.535
4.31AspGlu: 4.31 ± 1.601
3.316AspPhe: 3.316 ± 0.648
2.653AspGly: 2.653 ± 0.702
1.326AspHis: 1.326 ± 0.682
2.321AspIle: 2.321 ± 0.411
2.321AspLys: 2.321 ± 0.823
9.284AspLeu: 9.284 ± 4.775
0.663AspMet: 0.663 ± 0.341
2.653AspAsn: 2.653 ± 0.994
2.321AspPro: 2.321 ± 1.177
1.326AspGln: 1.326 ± 0.459
3.316AspArg: 3.316 ± 1.705
2.653AspSer: 2.653 ± 0.975
2.321AspThr: 2.321 ± 0.768
1.326AspVal: 1.326 ± 0.459
1.326AspTrp: 1.326 ± 0.576
1.658AspTyr: 1.658 ± 0.796
0.0AspXaa: 0.0 ± 0.0
Glu
5.637GluAla: 5.637 ± 1.744
0.995GluCys: 0.995 ± 0.512
2.984GluAsp: 2.984 ± 0.99
5.637GluGlu: 5.637 ± 1.349
2.984GluPhe: 2.984 ± 0.527
4.31GluGly: 4.31 ± 0.934
1.326GluHis: 1.326 ± 0.682
2.984GluIle: 2.984 ± 1.131
4.31GluLys: 4.31 ± 2.396
5.968GluLeu: 5.968 ± 1.914
1.326GluMet: 1.326 ± 0.757
2.321GluAsn: 2.321 ± 1.194
2.653GluPro: 2.653 ± 2.328
0.995GluGln: 0.995 ± 0.512
2.321GluArg: 2.321 ± 0.97
5.637GluSer: 5.637 ± 1.771
2.984GluThr: 2.984 ± 0.609
5.637GluVal: 5.637 ± 2.234
0.0GluTrp: 0.0 ± 0.0
2.653GluTyr: 2.653 ± 1.902
0.0GluXaa: 0.0 ± 0.0
Phe
2.321PheAla: 2.321 ± 1.194
1.326PheCys: 1.326 ± 0.682
3.647PheAsp: 3.647 ± 0.787
5.968PheGlu: 5.968 ± 1.505
3.647PhePhe: 3.647 ± 1.231
3.316PheGly: 3.316 ± 2.457
1.658PheHis: 1.658 ± 0.853
3.647PheIle: 3.647 ± 1.66
2.984PheLys: 2.984 ± 1.131
5.968PheLeu: 5.968 ± 2.417
0.995PheMet: 0.995 ± 0.512
2.984PheAsn: 2.984 ± 0.995
2.984PhePro: 2.984 ± 2.048
1.658PheGln: 1.658 ± 0.555
2.653PheArg: 2.653 ± 0.862
6.963PheSer: 6.963 ± 0.753
3.979PheThr: 3.979 ± 1.581
2.653PheVal: 2.653 ± 1.364
0.332PheTrp: 0.332 ± 0.171
0.663PheTyr: 0.663 ± 0.341
0.0PheXaa: 0.0 ± 0.0
Gly
4.973GlyAla: 4.973 ± 1.72
2.321GlyCys: 2.321 ± 0.859
1.989GlyAsp: 1.989 ± 1.018
4.973GlyGlu: 4.973 ± 0.748
4.31GlyPhe: 4.31 ± 0.955
2.984GlyGly: 2.984 ± 1.442
1.326GlyHis: 1.326 ± 0.892
2.321GlyIle: 2.321 ± 0.859
3.979GlyLys: 3.979 ± 0.692
5.305GlyLeu: 5.305 ± 1.73
0.995GlyMet: 0.995 ± 0.96
3.316GlyAsn: 3.316 ± 2.015
1.658GlyPro: 1.658 ± 1.258
2.321GlyGln: 2.321 ± 0.768
5.305GlyArg: 5.305 ± 0.882
5.305GlySer: 5.305 ± 1.192
3.647GlyThr: 3.647 ± 2.59
4.642GlyVal: 4.642 ± 0.958
0.663GlyTrp: 0.663 ± 0.341
1.326GlyTyr: 1.326 ± 0.576
0.0GlyXaa: 0.0 ± 0.0
His
1.326HisAla: 1.326 ± 0.576
0.332HisCys: 0.332 ± 0.517
1.989HisAsp: 1.989 ± 1.023
2.653HisGlu: 2.653 ± 0.915
1.989HisPhe: 1.989 ± 0.649
2.321HisGly: 2.321 ± 1.645
0.995HisHis: 0.995 ± 0.612
0.995HisIle: 0.995 ± 0.512
1.989HisLys: 1.989 ± 0.649
2.321HisLeu: 2.321 ± 1.194
0.0HisMet: 0.0 ± 0.0
1.326HisAsn: 1.326 ± 1.211
1.326HisPro: 1.326 ± 1.073
0.663HisGln: 0.663 ± 0.341
1.658HisArg: 1.658 ± 1.875
3.316HisSer: 3.316 ± 1.705
0.995HisThr: 0.995 ± 0.414
1.989HisVal: 1.989 ± 0.449
0.0HisTrp: 0.0 ± 0.0
1.326HisTyr: 1.326 ± 0.459
0.0HisXaa: 0.0 ± 0.0
Ile
2.984IleAla: 2.984 ± 0.908
1.326IleCys: 1.326 ± 0.576
3.979IleAsp: 3.979 ± 2.046
3.647IleGlu: 3.647 ± 0.934
3.316IlePhe: 3.316 ± 0.648
3.316IleGly: 3.316 ± 1.966
1.989IleHis: 1.989 ± 1.756
3.979IleIle: 3.979 ± 1.614
6.3IleLys: 6.3 ± 1.169
5.968IleLeu: 5.968 ± 1.826
2.321IleMet: 2.321 ± 0.859
1.326IleAsn: 1.326 ± 0.682
1.326IlePro: 1.326 ± 0.682
1.658IleGln: 1.658 ± 0.555
1.989IleArg: 1.989 ± 1.476
3.316IleSer: 3.316 ± 1.459
3.647IleThr: 3.647 ± 1.163
4.642IleVal: 4.642 ± 4.224
0.0IleTrp: 0.0 ± 0.0
1.658IleTyr: 1.658 ± 0.796
0.0IleXaa: 0.0 ± 0.0
Lys
2.321LysAla: 2.321 ± 1.177
1.326LysCys: 1.326 ± 0.682
3.316LysAsp: 3.316 ± 1.705
4.642LysGlu: 4.642 ± 0.822
5.305LysPhe: 5.305 ± 2.285
3.979LysGly: 3.979 ± 1.551
1.326LysHis: 1.326 ± 0.459
3.647LysIle: 3.647 ± 1.454
4.973LysLys: 4.973 ± 1.108
4.973LysLeu: 4.973 ± 1.6
1.326LysMet: 1.326 ± 0.779
4.31LysAsn: 4.31 ± 1.165
4.31LysPro: 4.31 ± 0.817
1.658LysGln: 1.658 ± 0.54
2.321LysArg: 2.321 ± 0.901
4.973LysSer: 4.973 ± 1.169
2.984LysThr: 2.984 ± 0.995
2.984LysVal: 2.984 ± 1.535
0.332LysTrp: 0.332 ± 0.171
0.663LysTyr: 0.663 ± 0.341
0.0LysXaa: 0.0 ± 0.0
Leu
6.631LeuAla: 6.631 ± 1.934
2.653LeuCys: 2.653 ± 1.364
6.631LeuAsp: 6.631 ± 2.245
5.968LeuGlu: 5.968 ± 1.055
4.973LeuPhe: 4.973 ± 1.405
5.305LeuGly: 5.305 ± 0.769
2.984LeuHis: 2.984 ± 1.535
6.3LeuIle: 6.3 ± 1.253
7.294LeuLys: 7.294 ± 2.553
5.305LeuLeu: 5.305 ± 2.242
1.326LeuMet: 1.326 ± 0.461
4.973LeuAsn: 4.973 ± 1.924
5.637LeuPro: 5.637 ± 2.38
1.658LeuGln: 1.658 ± 0.834
3.979LeuArg: 3.979 ± 0.897
7.626LeuSer: 7.626 ± 1.942
6.3LeuThr: 6.3 ± 1.425
7.294LeuVal: 7.294 ± 3.611
0.663LeuTrp: 0.663 ± 0.341
1.989LeuTyr: 1.989 ± 1.023
0.0LeuXaa: 0.0 ± 0.0
Met
2.653MetAla: 2.653 ± 0.919
0.332MetCys: 0.332 ± 0.171
0.332MetAsp: 0.332 ± 0.171
1.326MetGlu: 1.326 ± 0.664
0.0MetPhe: 0.0 ± 0.0
1.658MetGly: 1.658 ± 0.555
0.332MetHis: 0.332 ± 0.171
1.326MetIle: 1.326 ± 0.795
1.658MetLys: 1.658 ± 0.853
1.989MetLeu: 1.989 ± 0.681
0.663MetMet: 0.663 ± 0.341
0.663MetAsn: 0.663 ± 0.341
0.995MetPro: 0.995 ± 0.83
0.0MetGln: 0.0 ± 0.0
2.321MetArg: 2.321 ± 0.823
0.995MetSer: 0.995 ± 1.06
0.663MetThr: 0.663 ± 0.436
0.332MetVal: 0.332 ± 0.171
0.0MetTrp: 0.0 ± 0.0
0.995MetTyr: 0.995 ± 1.579
0.0MetXaa: 0.0 ± 0.0
Asn
1.989AsnAla: 1.989 ± 0.829
2.321AsnCys: 2.321 ± 0.743
0.663AsnAsp: 0.663 ± 0.341
1.326AsnGlu: 1.326 ± 0.664
2.653AsnPhe: 2.653 ± 0.441
2.653AsnGly: 2.653 ± 1.364
2.653AsnHis: 2.653 ± 1.546
4.973AsnIle: 4.973 ± 2.527
0.995AsnLys: 0.995 ± 0.512
4.642AsnLeu: 4.642 ± 0.721
0.663AsnMet: 0.663 ± 0.59
1.658AsnAsn: 1.658 ± 0.555
2.984AsnPro: 2.984 ± 1.243
0.663AsnGln: 0.663 ± 0.69
2.984AsnArg: 2.984 ± 1.005
3.316AsnSer: 3.316 ± 1.358
0.995AsnThr: 0.995 ± 0.414
2.984AsnVal: 2.984 ± 1.131
0.332AsnTrp: 0.332 ± 0.517
1.326AsnTyr: 1.326 ± 0.795
0.0AsnXaa: 0.0 ± 0.0
Pro
4.642ProAla: 4.642 ± 3.134
1.658ProCys: 1.658 ± 0.589
3.316ProAsp: 3.316 ± 0.641
2.984ProGlu: 2.984 ± 1.199
1.989ProPhe: 1.989 ± 1.616
2.653ProGly: 2.653 ± 0.84
1.989ProHis: 1.989 ± 0.833
2.653ProIle: 2.653 ± 0.84
1.658ProLys: 1.658 ± 0.795
3.979ProLeu: 3.979 ± 1.909
0.663ProMet: 0.663 ± 1.138
0.995ProAsn: 0.995 ± 0.512
1.989ProPro: 1.989 ± 1.616
1.326ProGln: 1.326 ± 1.328
1.989ProArg: 1.989 ± 0.904
2.653ProSer: 2.653 ± 0.994
2.653ProThr: 2.653 ± 1.242
2.984ProVal: 2.984 ± 1.699
0.995ProTrp: 0.995 ± 0.512
1.326ProTyr: 1.326 ± 1.506
0.0ProXaa: 0.0 ± 0.0
Gln
2.321GlnAla: 2.321 ± 1.348
0.663GlnCys: 0.663 ± 0.341
2.653GlnAsp: 2.653 ± 0.702
1.326GlnGlu: 1.326 ± 0.682
0.995GlnPhe: 0.995 ± 0.512
2.321GlnGly: 2.321 ± 1.546
0.663GlnHis: 0.663 ± 0.436
0.663GlnIle: 0.663 ± 0.341
1.658GlnLys: 1.658 ± 0.555
2.321GlnLeu: 2.321 ± 1.081
1.658GlnMet: 1.658 ± 0.834
0.995GlnAsn: 0.995 ± 0.612
0.995GlnPro: 0.995 ± 1.008
1.658GlnGln: 1.658 ± 1.31
0.995GlnArg: 0.995 ± 0.805
2.653GlnSer: 2.653 ± 1.242
2.321GlnThr: 2.321 ± 1.348
2.653GlnVal: 2.653 ± 1.546
0.332GlnTrp: 0.332 ± 0.171
0.332GlnTyr: 0.332 ± 0.517
0.0GlnXaa: 0.0 ± 0.0
Arg
4.642ArgAla: 4.642 ± 1.513
0.663ArgCys: 0.663 ± 1.46
1.658ArgAsp: 1.658 ± 0.853
2.321ArgGlu: 2.321 ± 0.823
4.31ArgPhe: 4.31 ± 1.601
4.973ArgGly: 4.973 ± 2.043
2.321ArgHis: 2.321 ± 1.168
3.979ArgIle: 3.979 ± 0.881
2.984ArgLys: 2.984 ± 1.535
4.973ArgLeu: 4.973 ± 1.011
0.663ArgMet: 0.663 ± 0.341
1.989ArgAsn: 1.989 ± 1.282
0.995ArgPro: 0.995 ± 0.512
0.663ArgGln: 0.663 ± 0.956
4.31ArgArg: 4.31 ± 1.1
2.653ArgSer: 2.653 ± 0.702
2.321ArgThr: 2.321 ± 0.743
1.989ArgVal: 1.989 ± 1.309
0.995ArgTrp: 0.995 ± 0.83
2.321ArgTyr: 2.321 ± 0.823
0.0ArgXaa: 0.0 ± 0.0
Ser
4.31SerAla: 4.31 ± 1.46
1.989SerCys: 1.989 ± 1.483
4.31SerAsp: 4.31 ± 1.455
3.979SerGlu: 3.979 ± 1.112
4.642SerPhe: 4.642 ± 1.054
6.631SerGly: 6.631 ± 1.391
2.653SerHis: 2.653 ± 0.862
5.305SerIle: 5.305 ± 1.28
5.305SerLys: 5.305 ± 0.961
7.958SerLeu: 7.958 ± 2.761
1.989SerMet: 1.989 ± 0.681
2.321SerAsn: 2.321 ± 1.348
3.647SerPro: 3.647 ± 1.876
3.316SerGln: 3.316 ± 1.209
4.973SerArg: 4.973 ± 1.48
8.952SerSer: 8.952 ± 3.363
4.31SerThr: 4.31 ± 0.509
3.979SerVal: 3.979 ± 1.933
0.332SerTrp: 0.332 ± 0.171
1.989SerTyr: 1.989 ± 0.833
0.0SerXaa: 0.0 ± 0.0
Thr
2.984ThrAla: 2.984 ± 2.048
0.0ThrCys: 0.0 ± 0.0
2.653ThrAsp: 2.653 ± 0.975
2.321ThrGlu: 2.321 ± 1.265
7.294ThrPhe: 7.294 ± 1.431
4.31ThrGly: 4.31 ± 1.132
1.326ThrHis: 1.326 ± 0.682
1.989ThrIle: 1.989 ± 1.014
1.658ThrLys: 1.658 ± 0.796
6.631ThrLeu: 6.631 ± 1.418
0.332ThrMet: 0.332 ± 0.171
2.321ThrAsn: 2.321 ± 0.694
3.647ThrPro: 3.647 ± 3.445
2.321ThrGln: 2.321 ± 1.808
2.984ThrArg: 2.984 ± 2.116
3.979ThrSer: 3.979 ± 4.366
2.321ThrThr: 2.321 ± 2.586
3.979ThrVal: 3.979 ± 2.449
0.995ThrTrp: 0.995 ± 0.512
1.658ThrTyr: 1.658 ± 1.41
0.0ThrXaa: 0.0 ± 0.0
Val
3.316ValAla: 3.316 ± 3.192
0.663ValCys: 0.663 ± 0.341
3.316ValAsp: 3.316 ± 1.705
3.979ValGlu: 3.979 ± 3.311
2.653ValPhe: 2.653 ± 0.897
4.973ValGly: 4.973 ± 2.972
1.658ValHis: 1.658 ± 0.54
2.984ValIle: 2.984 ± 1.249
3.979ValLys: 3.979 ± 1.551
5.637ValLeu: 5.637 ± 2.251
0.663ValMet: 0.663 ± 0.341
2.321ValAsn: 2.321 ± 0.823
3.647ValPro: 3.647 ± 1.375
3.647ValGln: 3.647 ± 0.62
3.316ValArg: 3.316 ± 1.139
6.963ValSer: 6.963 ± 0.837
3.316ValThr: 3.316 ± 1.505
5.305ValVal: 5.305 ± 2.242
0.663ValTrp: 0.663 ± 0.436
0.995ValTyr: 0.995 ± 1.186
0.0ValXaa: 0.0 ± 0.0
Trp
0.332TrpAla: 0.332 ± 0.171
0.332TrpCys: 0.332 ± 0.171
0.332TrpAsp: 0.332 ± 0.171
0.332TrpGlu: 0.332 ± 0.171
0.995TrpPhe: 0.995 ± 0.83
0.663TrpGly: 0.663 ± 0.341
0.663TrpHis: 0.663 ± 0.69
0.332TrpIle: 0.332 ± 0.171
0.995TrpLys: 0.995 ± 0.512
0.663TrpLeu: 0.663 ± 0.341
0.0TrpMet: 0.0 ± 0.0
0.332TrpAsn: 0.332 ± 0.517
0.663TrpPro: 0.663 ± 0.341
0.0TrpGln: 0.0 ± 0.0
0.332TrpArg: 0.332 ± 0.171
0.0TrpSer: 0.0 ± 0.0
0.332TrpThr: 0.332 ± 0.171
0.995TrpVal: 0.995 ± 0.414
0.332TrpTrp: 0.332 ± 0.171
0.332TrpTyr: 0.332 ± 0.797
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.989TyrAla: 1.989 ± 0.829
0.663TyrCys: 0.663 ± 1.138
1.658TyrAsp: 1.658 ± 0.853
2.321TyrGlu: 2.321 ± 0.823
0.995TyrPhe: 0.995 ± 0.512
0.995TyrGly: 0.995 ± 0.512
0.663TyrHis: 0.663 ± 1.128
1.989TyrIle: 1.989 ± 0.649
0.995TyrLys: 0.995 ± 0.612
3.316TyrLeu: 3.316 ± 0.983
0.332TyrMet: 0.332 ± 0.171
0.995TyrAsn: 0.995 ± 0.612
0.995TyrPro: 0.995 ± 1.06
1.326TyrGln: 1.326 ± 1.211
0.995TyrArg: 0.995 ± 0.414
2.653TyrSer: 2.653 ± 1.834
1.326TyrThr: 1.326 ± 0.682
0.663TyrVal: 0.663 ± 1.46
0.332TyrTrp: 0.332 ± 0.171
0.663TyrTyr: 0.663 ± 1.311
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 5 proteins (3017 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski