Fruit bat alphaherpesvirus 1

Taxonomy: Viruses; Duplodnaviria; Heunggongvirae; Peploviricota; Herviviricetes; Herpesvirales; Herpesviridae; Alphaherpesvirinae; Simplexvirus; Pteropodid alphaherpesvirus 1

Average proteome isoelectric point is 6.71

Get precalculated fractions of proteins

Acidic
pI < 6.8
6.8-7.4
pI > 7.4
Basic
    
All



Virtual 2D-PAGE plot for 68 proteins (isoelectric point calculated using IPC2_protein)

Get csv file with sequences according to given criteria:
        -     Method 

     -  kDa    
                                                                                      

* You can choose from 21 different methods for calculating isoelectric point

Summary statistics related to proteome-wise predictions


    
Protein with the lowest isoelectric point:
>tr|A0A060Q0V3|A0A060Q0V3_9ALPH Capsid vertex component 2 OS=Fruit bat alphaherpesvirus 1 OX=1343901 GN=UL25 PE=3 SV=1
MM1 pKa = 7.98RR2 pKa = 11.84DD3 pKa = 4.2DD4 pKa = 5.58LPLIDD9 pKa = 5.22PLLVDD14 pKa = 3.79EE15 pKa = 5.3TEE17 pKa = 4.29SSEE20 pKa = 5.37DD21 pKa = 3.75PDD23 pKa = 3.98DD24 pKa = 5.58LSIEE28 pKa = 4.29EE29 pKa = 4.12QFSLSSYY36 pKa = 8.1GTADD40 pKa = 3.61FFVSSAYY47 pKa = 10.45SRR49 pKa = 11.84LPSHH53 pKa = 6.23TQPVFSKK60 pKa = 10.24RR61 pKa = 11.84VFVFVLAFFFLKK73 pKa = 10.35PFQLASLCVYY83 pKa = 9.23YY84 pKa = 10.94HH85 pKa = 4.83EE86 pKa = 4.7TGRR89 pKa = 11.84LAALACVAAAVLGYY103 pKa = 10.25YY104 pKa = 8.34VLWCARR110 pKa = 11.84ACALYY115 pKa = 10.2WNIKK119 pKa = 7.31QDD121 pKa = 4.1RR122 pKa = 11.84LPLTPTAFWFLVVCFSGLALGALCAAAHH150 pKa = 5.62EE151 pKa = 4.53TFAVDD156 pKa = 4.59GLFDD160 pKa = 6.03LISTGQVLPPTDD172 pKa = 3.83PLRR175 pKa = 11.84VRR177 pKa = 11.84LLTIACVTMVGLWVAAADD195 pKa = 4.09SFAVAANFFLARR207 pKa = 11.84FWTRR211 pKa = 11.84AILNAPVAFF220 pKa = 4.58

Molecular weight: 24.27 kDa
Isoelectric point according different methods:





Protein with the highest isoelectric point:
>tr|A0A060PYC0|A0A060PYC0_9ALPH Envelope glycoprotein K OS=Fruit bat alphaherpesvirus 1 OX=1343901 GN=UL53 PE=3 SV=1
MM1 pKa = 7.11ATRR4 pKa = 11.84RR5 pKa = 11.84TARR8 pKa = 11.84PPARR12 pKa = 11.84TPAPSRR18 pKa = 11.84PVLEE22 pKa = 5.24RR23 pKa = 11.84YY24 pKa = 9.48ASSSSTSTRR33 pKa = 11.84GGSIYY38 pKa = 10.32DD39 pKa = 3.42TDD41 pKa = 4.02DD42 pKa = 3.85RR43 pKa = 11.84PGGEE47 pKa = 4.09VQRR50 pKa = 11.84RR51 pKa = 11.84HH52 pKa = 4.57YY53 pKa = 9.38HH54 pKa = 4.2QCEE57 pKa = 4.11EE58 pKa = 4.07DD59 pKa = 3.31WPVYY63 pKa = 10.38SDD65 pKa = 3.67SFEE68 pKa = 4.29SSSDD72 pKa = 3.88DD73 pKa = 3.68EE74 pKa = 5.75LDD76 pKa = 3.61AAMSAPTPSEE86 pKa = 3.48PTGRR90 pKa = 11.84GRR92 pKa = 11.84GAGRR96 pKa = 11.84SAAPRR101 pKa = 11.84APAARR106 pKa = 11.84RR107 pKa = 11.84APASGGQTNTRR118 pKa = 11.84GTRR121 pKa = 11.84GTAANPPTSRR131 pKa = 11.84PPALEE136 pKa = 4.26PDD138 pKa = 3.53ADD140 pKa = 3.71VTARR144 pKa = 11.84AGQGRR149 pKa = 11.84RR150 pKa = 11.84ARR152 pKa = 11.84KK153 pKa = 8.56PATKK157 pKa = 9.37PAPPPTIDD165 pKa = 3.53SQAKK169 pKa = 9.77GLTASNLLQFSGAPSSPTSPWNGRR193 pKa = 11.84TAIFNKK199 pKa = 9.23RR200 pKa = 11.84TFCAAVGRR208 pKa = 11.84VAAKK212 pKa = 9.92HH213 pKa = 5.54ARR215 pKa = 11.84QAAAKK220 pKa = 8.87LWDD223 pKa = 3.65MSNPQNDD230 pKa = 3.83EE231 pKa = 4.02EE232 pKa = 5.42LNTLLGATNIRR243 pKa = 11.84ITVCEE248 pKa = 4.16GQDD251 pKa = 3.63LLPRR255 pKa = 11.84ANDD258 pKa = 3.83LVTGACPEE266 pKa = 4.29PEE268 pKa = 4.34STSRR272 pKa = 11.84TPARR276 pKa = 11.84SVARR280 pKa = 11.84STSRR284 pKa = 11.84ARR286 pKa = 11.84RR287 pKa = 11.84PNN289 pKa = 3.15

Molecular weight: 30.63 kDa
Isoelectric point according different methods:





Peptides (in silico digests for buttom-up proteomics)

Below you can find in silico digests of the whole proteome with Trypsin, Chymotrypsin, Trypsin+LysC, LysN, ArgC proteases suitable for different mass spec machines.

Try
ESI
ChTry
ESI
ArgC
ESI
LysN
ESI
TryLysC
ESI

Try
MALDI
ChTry
MALDI
ArgC
MALDI
LysN
MALDI
TryLysC
MALDI

Try
LTQ
ChTry
LTQ
ArgC
LTQ
LysN
LTQ
TryLysC
LTQ

Try
MSlow
ChTry
MSlow
ArgC
MSlow
LysN
MSlow
TryLysC
MSlow

Try
MShigh
ChTry
MShigh
ArgC
MShigh
LysN
MShigh
TryLysC
MShigh

General Statistics

Number of major isoforms

Number of additional isoforms

Number of all proteins

Number of amino acids

Min. Seq. Length

Max. Seq. Length

Avg. Seq. Length

Avg. Mol. Weight

68

0

68

36182

81

2219

532.1

58.25

Amino acid frequency

Ala

Cys

Asp

Glu

Phe

Gly

His

Ile

Lys

Leu

11.321 ± 0.461

1.852 ± 0.13

4.679 ± 0.134

5.384 ± 0.189

3.958 ± 0.188

5.845 ± 0.18

2.653 ± 0.113

3.596 ± 0.205

2.36 ± 0.112

10.56 ± 0.318

Met

Asn

Gln

Pro

Arg

Ser

Thr

Val

Trp

Tyr

1.755 ± 0.098

2.659 ± 0.157

8.018 ± 0.317

3.839 ± 0.126

7.258 ± 0.244

7.728 ± 0.277

6.362 ± 0.247

6.42 ± 0.169

1.205 ± 0.087

2.548 ± 0.142
Note: For amino acid frequency statistics the error has been estimated with the bootstraping (x100) at the protein level

Most of the basic statistics you can see at this page can be downloaded from this CSV file

For dipeptide frequency statistics click here
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski