Amino acid dipepetide frequency for Luteimonas chenhongjianii

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	19.348AlaAla: 19.348 ± 0.235	1.217AlaCys: 1.217 ± 0.039	7.852AlaAsp: 7.852 ± 0.109	6.923AlaGlu: 6.923 ± 0.11	4.285AlaPhe: 4.285 ± 0.071	12.108AlaGly: 12.108 ± 0.173	2.82AlaHis: 2.82 ± 0.058	5.657AlaIle: 5.657 ± 0.098	2.791AlaLys: 2.791 ± 0.073	16.216AlaLeu: 16.216 ± 0.21	3.432AlaMet: 3.432 ± 0.06	2.67AlaAsn: 2.67 ± 0.057	7.236AlaPro: 7.236 ± 0.139	5.371AlaGln: 5.371 ± 0.098	11.256AlaArg: 11.256 ± 0.146	6.831AlaSer: 6.831 ± 0.101	6.593AlaThr: 6.593 ± 0.091	9.032AlaVal: 9.032 ± 0.122	2.069AlaTrp: 2.069 ± 0.06	2.389AlaTyr: 2.389 ± 0.048	0.0AlaXaa: 0.0 ± 0.0
Cys	1.047CysAla: 1.047 ± 0.035	0.08CysCys: 0.08 ± 0.01	0.463CysAsp: 0.463 ± 0.022	0.438CysGlu: 0.438 ± 0.024	0.217CysPhe: 0.217 ± 0.015	0.853CysGly: 0.853 ± 0.029	0.189CysHis: 0.189 ± 0.014	0.349CysIle: 0.349 ± 0.019	0.136CysLys: 0.136 ± 0.014	0.65CysLeu: 0.65 ± 0.026	0.138CysMet: 0.138 ± 0.013	0.196CysAsn: 0.196 ± 0.015	0.389CysPro: 0.389 ± 0.025	0.198CysGln: 0.198 ± 0.015	0.592CysArg: 0.592 ± 0.028	0.44CysSer: 0.44 ± 0.024	0.402CysThr: 0.402 ± 0.023	0.659CysVal: 0.659 ± 0.031	0.1CysTrp: 0.1 ± 0.009	0.17CysTyr: 0.17 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	10.179AspAla: 10.179 ± 0.144	0.42AspCys: 0.42 ± 0.022	3.887AspAsp: 3.887 ± 0.07	3.265AspGlu: 3.265 ± 0.059	2.033AspPhe: 2.033 ± 0.048	6.377AspGly: 6.377 ± 0.103	1.132AspHis: 1.132 ± 0.039	2.675AspIle: 2.675 ± 0.056	1.131AspLys: 1.131 ± 0.035	5.697AspLeu: 5.697 ± 0.084	1.244AspMet: 1.244 ± 0.036	1.202AspAsn: 1.202 ± 0.036	3.714AspPro: 3.714 ± 0.065	1.544AspGln: 1.544 ± 0.037	4.367AspArg: 4.367 ± 0.067	2.524AspSer: 2.524 ± 0.066	3.066AspThr: 3.066 ± 0.066	4.776AspVal: 4.776 ± 0.1	1.187AspTrp: 1.187 ± 0.037	1.491AspTyr: 1.491 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	7.65GluAla: 7.65 ± 0.106	0.302GluCys: 0.302 ± 0.019	2.719GluAsp: 2.719 ± 0.055	2.286GluGlu: 2.286 ± 0.053	1.729GluPhe: 1.729 ± 0.04	4.091GluGly: 4.091 ± 0.073	1.319GluHis: 1.319 ± 0.039	2.63GluIle: 2.63 ± 0.061	1.252GluLys: 1.252 ± 0.043	5.731GluLeu: 5.731 ± 0.086	1.139GluMet: 1.139 ± 0.039	1.161GluAsn: 1.161 ± 0.038	2.417GluPro: 2.417 ± 0.05	2.204GluGln: 2.204 ± 0.058	5.248GluArg: 5.248 ± 0.089	2.65GluSer: 2.65 ± 0.057	2.845GluThr: 2.845 ± 0.066	3.925GluVal: 3.925 ± 0.068	0.665GluTrp: 0.665 ± 0.025	1.087GluTyr: 1.087 ± 0.029	0.0GluXaa: 0.0 ± 0.0
Phe	4.514PheAla: 4.514 ± 0.076	0.304PheCys: 0.304 ± 0.018	2.9PheAsp: 2.9 ± 0.053	2.091PheGlu: 2.091 ± 0.044	1.151PhePhe: 1.151 ± 0.042	3.348PheGly: 3.348 ± 0.062	0.727PheHis: 0.727 ± 0.031	1.193PheIle: 1.193 ± 0.035	0.747PheLys: 0.747 ± 0.032	2.852PheLeu: 2.852 ± 0.056	0.628PheMet: 0.628 ± 0.027	0.974PheAsn: 0.974 ± 0.034	1.443PhePro: 1.443 ± 0.044	0.902PheGln: 0.902 ± 0.03	2.172PheArg: 2.172 ± 0.059	1.778PheSer: 1.778 ± 0.041	1.567PheThr: 1.567 ± 0.046	2.765PheVal: 2.765 ± 0.058	0.47PheTrp: 0.47 ± 0.025	0.723PheTyr: 0.723 ± 0.03	0.0PheXaa: 0.0 ± 0.0
Gly	10.34GlyAla: 10.34 ± 0.177	0.729GlyCys: 0.729 ± 0.031	5.387GlyAsp: 5.387 ± 0.099	4.829GlyGlu: 4.829 ± 0.08	3.451GlyPhe: 3.451 ± 0.063	7.668GlyGly: 7.668 ± 0.149	2.12GlyHis: 2.12 ± 0.057	4.185GlyIle: 4.185 ± 0.07	2.483GlyLys: 2.483 ± 0.061	8.992GlyLeu: 8.992 ± 0.108	2.34GlyMet: 2.34 ± 0.055	2.264GlyAsn: 2.264 ± 0.07	3.471GlyPro: 3.471 ± 0.07	2.911GlyGln: 2.911 ± 0.056	6.917GlyArg: 6.917 ± 0.089	4.671GlySer: 4.671 ± 0.103	4.575GlyThr: 4.575 ± 0.092	6.671GlyVal: 6.671 ± 0.084	1.576GlyTrp: 1.576 ± 0.045	2.22GlyTyr: 2.22 ± 0.053	0.0GlyXaa: 0.0 ± 0.0
His	3.231HisAla: 3.231 ± 0.068	0.233HisCys: 0.233 ± 0.017	1.378HisAsp: 1.378 ± 0.038	1.052HisGlu: 1.052 ± 0.033	0.751HisPhe: 0.751 ± 0.031	2.26HisGly: 2.26 ± 0.063	0.586HisHis: 0.586 ± 0.025	0.745HisIle: 0.745 ± 0.032	0.396HisLys: 0.396 ± 0.018	2.087HisLeu: 2.087 ± 0.049	0.418HisMet: 0.418 ± 0.02	0.477HisAsn: 0.477 ± 0.02	1.417HisPro: 1.417 ± 0.043	0.58HisGln: 0.58 ± 0.026	1.686HisArg: 1.686 ± 0.045	0.902HisSer: 0.902 ± 0.03	0.95HisThr: 0.95 ± 0.035	1.755HisVal: 1.755 ± 0.043	0.442HisTrp: 0.442 ± 0.025	0.57HisTyr: 0.57 ± 0.024	0.0HisXaa: 0.0 ± 0.0
Ile	6.765IleAla: 6.765 ± 0.093	0.362IleCys: 0.362 ± 0.02	3.563IleAsp: 3.563 ± 0.074	3.229IleGlu: 3.229 ± 0.064	1.109IlePhe: 1.109 ± 0.033	4.568IleGly: 4.568 ± 0.077	0.833IleHis: 0.833 ± 0.025	1.34IleIle: 1.34 ± 0.041	0.919IleLys: 0.919 ± 0.037	3.012IleLeu: 3.012 ± 0.059	0.519IleMet: 0.519 ± 0.024	1.128IleAsn: 1.128 ± 0.033	2.059IlePro: 2.059 ± 0.056	1.047IleGln: 1.047 ± 0.036	2.824IleArg: 2.824 ± 0.057	2.088IleSer: 2.088 ± 0.057	2.029IleThr: 2.029 ± 0.051	3.516IleVal: 3.516 ± 0.062	0.439IleTrp: 0.439 ± 0.03	0.806IleTyr: 0.806 ± 0.028	0.0IleXaa: 0.0 ± 0.0
Lys	2.67LysAla: 2.67 ± 0.072	0.102LysCys: 0.102 ± 0.011	1.137LysAsp: 1.137 ± 0.039	0.896LysGlu: 0.896 ± 0.039	0.636LysPhe: 0.636 ± 0.024	1.648LysGly: 1.648 ± 0.043	0.449LysHis: 0.449 ± 0.021	0.989LysIle: 0.989 ± 0.035	0.757LysLys: 0.757 ± 0.047	2.365LysLeu: 2.365 ± 0.055	0.474LysMet: 0.474 ± 0.025	0.476LysAsn: 0.476 ± 0.023	1.461LysPro: 1.461 ± 0.048	0.899LysGln: 0.899 ± 0.03	1.848LysArg: 1.848 ± 0.05	1.209LysSer: 1.209 ± 0.043	1.23LysThr: 1.23 ± 0.042	1.723LysVal: 1.723 ± 0.06	0.263LysTrp: 0.263 ± 0.018	0.489LysTyr: 0.489 ± 0.025	0.0LysXaa: 0.0 ± 0.0
Leu	15.115LeuAla: 15.115 ± 0.19	0.87LeuCys: 0.87 ± 0.031	7.164LeuAsp: 7.164 ± 0.12	5.485LeuGlu: 5.485 ± 0.086	3.281LeuPhe: 3.281 ± 0.059	8.636LeuGly: 8.636 ± 0.101	2.437LeuHis: 2.437 ± 0.058	3.8LeuIle: 3.8 ± 0.068	2.321LeuLys: 2.321 ± 0.053	11.812LeuLeu: 11.812 ± 0.202	2.085LeuMet: 2.085 ± 0.05	2.027LeuAsn: 2.027 ± 0.055	6.477LeuPro: 6.477 ± 0.107	3.987LeuGln: 3.987 ± 0.06	9.327LeuArg: 9.327 ± 0.127	5.619LeuSer: 5.619 ± 0.082	4.712LeuThr: 4.712 ± 0.077	8.168LeuVal: 8.168 ± 0.114	1.374LeuTrp: 1.374 ± 0.044	2.014LeuTyr: 2.014 ± 0.051	0.0LeuXaa: 0.0 ± 0.0
Met	2.664MetAla: 2.664 ± 0.064	0.154MetCys: 0.154 ± 0.014	1.084MetAsp: 1.084 ± 0.036	0.864MetGlu: 0.864 ± 0.03	0.614MetPhe: 0.614 ± 0.029	1.544MetGly: 1.544 ± 0.043	0.486MetHis: 0.486 ± 0.023	0.889MetIle: 0.889 ± 0.034	0.634MetLys: 0.634 ± 0.025	2.586MetLeu: 2.586 ± 0.051	0.447MetMet: 0.447 ± 0.024	0.525MetAsn: 0.525 ± 0.02	1.558MetPro: 1.558 ± 0.043	0.958MetGln: 0.958 ± 0.031	2.05MetArg: 2.05 ± 0.048	1.563MetSer: 1.563 ± 0.04	1.458MetThr: 1.458 ± 0.044	1.444MetVal: 1.444 ± 0.047	0.194MetTrp: 0.194 ± 0.015	0.342MetTyr: 0.342 ± 0.02	0.0MetXaa: 0.0 ± 0.0
Asn	3.149AsnAla: 3.149 ± 0.07	0.197AsnCys: 0.197 ± 0.017	1.249AsnAsp: 1.249 ± 0.038	1.075AsnGlu: 1.075 ± 0.036	0.825AsnPhe: 0.825 ± 0.031	2.026AsnGly: 2.026 ± 0.053	0.426AsnHis: 0.426 ± 0.021	0.96AsnIle: 0.96 ± 0.033	0.457AsnLys: 0.457 ± 0.025	2.229AsnLeu: 2.229 ± 0.059	0.421AsnMet: 0.421 ± 0.023	0.531AsnAsn: 0.531 ± 0.025	1.647AsnPro: 1.647 ± 0.044	0.598AsnGln: 0.598 ± 0.027	1.711AsnArg: 1.711 ± 0.049	0.986AsnSer: 0.986 ± 0.037	1.227AsnThr: 1.227 ± 0.046	1.774AsnVal: 1.774 ± 0.05	0.352AsnTrp: 0.352 ± 0.021	0.545AsnTyr: 0.545 ± 0.025	0.0AsnXaa: 0.0 ± 0.0
Pro	7.839ProAla: 7.839 ± 0.126	0.318ProCys: 0.318 ± 0.018	3.977ProAsp: 3.977 ± 0.066	3.369ProGlu: 3.369 ± 0.071	1.637ProPhe: 1.637 ± 0.043	5.296ProGly: 5.296 ± 0.092	1.083ProHis: 1.083 ± 0.035	1.833ProIle: 1.833 ± 0.049	1.091ProLys: 1.091 ± 0.039	5.453ProLeu: 5.453 ± 0.096	1.338ProMet: 1.338 ± 0.04	1.015ProAsn: 1.015 ± 0.031	3.15ProPro: 3.15 ± 0.074	1.949ProGln: 1.949 ± 0.055	3.892ProArg: 3.892 ± 0.071	2.625ProSer: 2.625 ± 0.056	2.579ProThr: 2.579 ± 0.056	4.566ProVal: 4.566 ± 0.072	0.846ProTrp: 0.846 ± 0.036	1.073ProTyr: 1.073 ± 0.038	0.0ProXaa: 0.0 ± 0.0
Gln	5.178GlnAla: 5.178 ± 0.08	0.203GlnCys: 0.203 ± 0.016	1.529GlnAsp: 1.529 ± 0.042	1.284GlnGlu: 1.284 ± 0.038	1.053GlnPhe: 1.053 ± 0.033	2.489GlnGly: 2.489 ± 0.052	0.74GlnHis: 0.74 ± 0.028	1.516GlnIle: 1.516 ± 0.043	0.704GlnLys: 0.704 ± 0.03	3.877GlnLeu: 3.877 ± 0.063	0.787GlnMet: 0.787 ± 0.028	0.664GlnAsn: 0.664 ± 0.028	2.021GlnPro: 2.021 ± 0.048	1.65GlnGln: 1.65 ± 0.048	3.432GlnArg: 3.432 ± 0.068	1.778GlnSer: 1.778 ± 0.052	1.623GlnThr: 1.623 ± 0.049	2.784GlnVal: 2.784 ± 0.051	0.501GlnTrp: 0.501 ± 0.02	0.693GlnTyr: 0.693 ± 0.026	0.0GlnXaa: 0.0 ± 0.0
Arg	9.844ArgAla: 9.844 ± 0.111	0.534ArgCys: 0.534 ± 0.025	5.165ArgAsp: 5.165 ± 0.076	5.071ArgGlu: 5.071 ± 0.084	3.113ArgPhe: 3.113 ± 0.051	5.96ArgGly: 5.96 ± 0.081	2.015ArgHis: 2.015 ± 0.055	4.226ArgIle: 4.226 ± 0.074	1.718ArgLys: 1.718 ± 0.054	8.95ArgLeu: 8.95 ± 0.13	2.17ArgMet: 2.17 ± 0.046	1.99ArgAsn: 1.99 ± 0.046	3.991ArgPro: 3.991 ± 0.085	2.793ArgGln: 2.793 ± 0.062	6.789ArgArg: 6.789 ± 0.113	3.907ArgSer: 3.907 ± 0.065	3.805ArgThr: 3.805 ± 0.067	5.885ArgVal: 5.885 ± 0.085	1.404ArgTrp: 1.404 ± 0.04	2.197ArgTyr: 2.197 ± 0.047	0.0ArgXaa: 0.0 ± 0.0
Ser	6.438SerAla: 6.438 ± 0.107	0.361SerCys: 0.361 ± 0.017	2.891SerAsp: 2.891 ± 0.054	2.526SerGlu: 2.526 ± 0.055	1.736SerPhe: 1.736 ± 0.045	5.259SerGly: 5.259 ± 0.104	1.03SerHis: 1.03 ± 0.031	2.167SerIle: 2.167 ± 0.053	1.133SerLys: 1.133 ± 0.035	5.136SerLeu: 5.136 ± 0.075	1.089SerMet: 1.089 ± 0.03	1.338SerAsn: 1.338 ± 0.046	2.882SerPro: 2.882 ± 0.064	1.689SerGln: 1.689 ± 0.043	3.924SerArg: 3.924 ± 0.069	2.633SerSer: 2.633 ± 0.06	2.689SerThr: 2.689 ± 0.055	3.682SerVal: 3.682 ± 0.075	0.746SerTrp: 0.746 ± 0.025	1.124SerTyr: 1.124 ± 0.036	0.0SerXaa: 0.0 ± 0.0
Thr	6.151ThrAla: 6.151 ± 0.094	0.368ThrCys: 0.368 ± 0.022	2.534ThrAsp: 2.534 ± 0.054	2.128ThrGlu: 2.128 ± 0.044	1.646ThrPhe: 1.646 ± 0.036	4.827ThrGly: 4.827 ± 0.098	1.107ThrHis: 1.107 ± 0.035	2.238ThrIle: 2.238 ± 0.058	0.824ThrLys: 0.824 ± 0.032	6.255ThrLeu: 6.255 ± 0.103	1.001ThrMet: 1.001 ± 0.037	0.964ThrAsn: 0.964 ± 0.043	3.653ThrPro: 3.653 ± 0.069	1.483ThrGln: 1.483 ± 0.042	4.053ThrArg: 4.053 ± 0.065	2.369ThrSer: 2.369 ± 0.068	2.632ThrThr: 2.632 ± 0.07	3.93ThrVal: 3.93 ± 0.072	0.675ThrTrp: 0.675 ± 0.03	0.933ThrTyr: 0.933 ± 0.032	0.0ThrXaa: 0.0 ± 0.0
Val	9.922ValAla: 9.922 ± 0.127	0.612ValCys: 0.612 ± 0.023	5.06ValAsp: 5.06 ± 0.089	4.675ValGlu: 4.675 ± 0.084	2.656ValPhe: 2.656 ± 0.059	5.906ValGly: 5.906 ± 0.111	1.628ValHis: 1.628 ± 0.044	3.292ValIle: 3.292 ± 0.063	1.44ValLys: 1.44 ± 0.046	8.405ValLeu: 8.405 ± 0.106	1.546ValMet: 1.546 ± 0.04	1.814ValAsn: 1.814 ± 0.061	4.086ValPro: 4.086 ± 0.071	2.369ValGln: 2.369 ± 0.055	6.021ValArg: 6.021 ± 0.088	3.983ValSer: 3.983 ± 0.066	3.842ValThr: 3.842 ± 0.065	6.354ValVal: 6.354 ± 0.102	0.912ValTrp: 0.912 ± 0.035	1.444ValTyr: 1.444 ± 0.039	0.0ValXaa: 0.0 ± 0.0
Trp	1.307TrpAla: 1.307 ± 0.042	0.162TrpCys: 0.162 ± 0.013	0.705TrpAsp: 0.705 ± 0.027	0.535TrpGlu: 0.535 ± 0.022	0.532TrpPhe: 0.532 ± 0.022	0.903TrpGly: 0.903 ± 0.033	0.378TrpHis: 0.378 ± 0.019	0.747TrpIle: 0.747 ± 0.027	0.356TrpLys: 0.356 ± 0.02	2.186TrpLeu: 2.186 ± 0.06	0.457TrpMet: 0.457 ± 0.022	0.443TrpAsn: 0.443 ± 0.024	0.767TrpPro: 0.767 ± 0.032	0.687TrpGln: 0.687 ± 0.024	1.526TrpArg: 1.526 ± 0.046	0.829TrpSer: 0.829 ± 0.028	0.802TrpThr: 0.802 ± 0.033	0.897TrpVal: 0.897 ± 0.035	0.301TrpTrp: 0.301 ± 0.018	0.336TrpTyr: 0.336 ± 0.019	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.744TyrAla: 2.744 ± 0.06	0.179TyrCys: 0.179 ± 0.014	1.266TyrAsp: 1.266 ± 0.041	1.031TyrGlu: 1.031 ± 0.037	0.792TyrPhe: 0.792 ± 0.029	2.034TyrGly: 2.034 ± 0.052	0.41TyrHis: 0.41 ± 0.021	0.726TyrIle: 0.726 ± 0.031	0.432TyrLys: 0.432 ± 0.021	2.222TyrLeu: 2.222 ± 0.054	0.384TyrMet: 0.384 ± 0.019	0.525TyrAsn: 0.525 ± 0.026	1.093TyrPro: 1.093 ± 0.035	0.685TyrGln: 0.685 ± 0.026	1.89TyrArg: 1.89 ± 0.046	1.087TyrSer: 1.087 ± 0.039	1.147TyrThr: 1.147 ± 0.034	1.659TyrVal: 1.659 ± 0.043	0.34TyrTrp: 0.34 ± 0.02	0.549TyrTyr: 0.549 ± 0.027	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 2887 proteins (957244 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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