Amino acid dipepetide frequency for Pseudoalteromonas atlantica (strain T6c / ATCC BAA-1087)

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10^-3.

For more information see sequence space article on Wikipedia.

	Ala	Cys	Asp	Glu	Phe	Gly	His	Ile	Lys	Leu	Met	Asn	Pro	Gln	Arg	Ser	Thr	Val	Trp	Tyr	Xaa
Ala	7.437AlaAla: 7.437 ± 0.094	0.947AlaCys: 0.947 ± 0.026	4.925AlaAsp: 4.925 ± 0.065	4.836AlaGlu: 4.836 ± 0.067	3.761AlaPhe: 3.761 ± 0.055	6.088AlaGly: 6.088 ± 0.085	1.83AlaHis: 1.83 ± 0.035	5.739AlaIle: 5.739 ± 0.068	5.076AlaLys: 5.076 ± 0.066	10.052AlaLeu: 10.052 ± 0.108	2.5AlaMet: 2.5 ± 0.049	4.021AlaAsn: 4.021 ± 0.059	3.222AlaPro: 3.222 ± 0.072	4.746AlaGln: 4.746 ± 0.07	3.479AlaArg: 3.479 ± 0.054	5.952AlaSer: 5.952 ± 0.072	4.677AlaThr: 4.677 ± 0.08	5.667AlaVal: 5.667 ± 0.064	0.94AlaTrp: 0.94 ± 0.025	2.633AlaTyr: 2.633 ± 0.043	0.0AlaXaa: 0.0 ± 0.0
Cys	0.859CysAla: 0.859 ± 0.027	0.158CysCys: 0.158 ± 0.011	0.555CysAsp: 0.555 ± 0.022	0.605CysGlu: 0.605 ± 0.022	0.427CysPhe: 0.427 ± 0.017	0.787CysGly: 0.787 ± 0.031	0.324CysHis: 0.324 ± 0.015	0.638CysIle: 0.638 ± 0.022	0.387CysLys: 0.387 ± 0.016	0.957CysLeu: 0.957 ± 0.029	0.239CysMet: 0.239 ± 0.011	0.332CysAsn: 0.332 ± 0.016	0.418CysPro: 0.418 ± 0.017	0.464CysGln: 0.464 ± 0.017	0.369CysArg: 0.369 ± 0.018	0.697CysSer: 0.697 ± 0.024	0.484CysThr: 0.484 ± 0.019	0.658CysVal: 0.658 ± 0.022	0.125CysTrp: 0.125 ± 0.009	0.326CysTyr: 0.326 ± 0.015	0.0CysXaa: 0.0 ± 0.0
Asp	5.129AspAla: 5.129 ± 0.082	0.527AspCys: 0.527 ± 0.02	3.603AspAsp: 3.603 ± 0.062	4.072AspGlu: 4.072 ± 0.065	2.73AspPhe: 2.73 ± 0.048	4.028AspGly: 4.028 ± 0.066	1.026AspHis: 1.026 ± 0.029	4.407AspIle: 4.407 ± 0.051	3.31AspLys: 3.31 ± 0.059	5.209AspLeu: 5.209 ± 0.066	1.549AspMet: 1.549 ± 0.039	2.831AspAsn: 2.831 ± 0.067	2.103AspPro: 2.103 ± 0.037	1.763AspGln: 1.763 ± 0.035	1.986AspArg: 1.986 ± 0.041	3.518AspSer: 3.518 ± 0.053	3.288AspThr: 3.288 ± 0.068	4.377AspVal: 4.377 ± 0.057	0.923AspTrp: 0.923 ± 0.028	2.097AspTyr: 2.097 ± 0.04	0.0AspXaa: 0.0 ± 0.0
Glu	4.753GluAla: 4.753 ± 0.063	0.444GluCys: 0.444 ± 0.016	2.817GluAsp: 2.817 ± 0.051	3.083GluGlu: 3.083 ± 0.057	2.519GluPhe: 2.519 ± 0.046	3.255GluGly: 3.255 ± 0.056	1.735GluHis: 1.735 ± 0.036	3.395GluIle: 3.395 ± 0.049	3.224GluLys: 3.224 ± 0.046	6.428GluLeu: 6.428 ± 0.08	1.487GluMet: 1.487 ± 0.031	2.724GluAsn: 2.724 ± 0.044	1.993GluPro: 1.993 ± 0.039	4.099GluGln: 4.099 ± 0.061	3.116GluArg: 3.116 ± 0.048	3.505GluSer: 3.505 ± 0.056	2.956GluThr: 2.956 ± 0.05	3.862GluVal: 3.862 ± 0.056	0.622GluTrp: 0.622 ± 0.022	1.841GluTyr: 1.841 ± 0.033	0.0GluXaa: 0.0 ± 0.0
Phe	3.944PheAla: 3.944 ± 0.052	0.514PheCys: 0.514 ± 0.018	3.065PheAsp: 3.065 ± 0.053	2.6PheGlu: 2.6 ± 0.045	1.795PhePhe: 1.795 ± 0.039	3.203PheGly: 3.203 ± 0.056	0.828PheHis: 0.828 ± 0.025	2.792PheIle: 2.792 ± 0.044	1.958PheLys: 1.958 ± 0.038	3.347PheLeu: 3.347 ± 0.058	1.127PheMet: 1.127 ± 0.031	2.177PheAsn: 2.177 ± 0.042	1.432PhePro: 1.432 ± 0.033	1.16PheGln: 1.16 ± 0.028	1.507PheArg: 1.507 ± 0.034	3.796PheSer: 3.796 ± 0.058	2.599PheThr: 2.599 ± 0.043	2.954PheVal: 2.954 ± 0.042	0.563PheTrp: 0.563 ± 0.021	1.508PheTyr: 1.508 ± 0.035	0.0PheXaa: 0.0 ± 0.0
Gly	5.507GlyAla: 5.507 ± 0.073	0.804GlyCys: 0.804 ± 0.024	3.971GlyAsp: 3.971 ± 0.06	4.135GlyGlu: 4.135 ± 0.052	3.415GlyPhe: 3.415 ± 0.058	4.81GlyGly: 4.81 ± 0.081	1.529GlyHis: 1.529 ± 0.035	4.539GlyIle: 4.539 ± 0.069	3.742GlyLys: 3.742 ± 0.066	7.006GlyLeu: 7.006 ± 0.065	1.905GlyMet: 1.905 ± 0.033	2.701GlyAsn: 2.701 ± 0.058	1.801GlyPro: 1.801 ± 0.038	3.023GlyGln: 3.023 ± 0.05	2.941GlyArg: 2.941 ± 0.048	4.187GlySer: 4.187 ± 0.068	3.479GlyThr: 3.479 ± 0.068	5.171GlyVal: 5.171 ± 0.067	0.967GlyTrp: 0.967 ± 0.024	2.563GlyTyr: 2.563 ± 0.046	0.0GlyXaa: 0.0 ± 0.0
His	1.79HisAla: 1.79 ± 0.035	0.316HisCys: 0.316 ± 0.015	1.18HisAsp: 1.18 ± 0.028	1.166HisGlu: 1.166 ± 0.032	1.171HisPhe: 1.171 ± 0.028	1.508HisGly: 1.508 ± 0.03	0.678HisHis: 0.678 ± 0.027	1.491HisIle: 1.491 ± 0.036	1.133HisLys: 1.133 ± 0.03	2.178HisLeu: 2.178 ± 0.04	0.579HisMet: 0.579 ± 0.02	0.962HisAsn: 0.962 ± 0.025	1.161HisPro: 1.161 ± 0.032	1.209HisGln: 1.209 ± 0.033	1.029HisArg: 1.029 ± 0.028	1.555HisSer: 1.555 ± 0.036	1.16HisThr: 1.16 ± 0.032	1.451HisVal: 1.451 ± 0.033	0.4HisTrp: 0.4 ± 0.017	0.926HisTyr: 0.926 ± 0.027	0.0HisXaa: 0.0 ± 0.0
Ile	6.167IleAla: 6.167 ± 0.059	0.682IleCys: 0.682 ± 0.023	4.345IleAsp: 4.345 ± 0.056	4.408IleGlu: 4.408 ± 0.056	2.266IlePhe: 2.266 ± 0.042	4.535IleGly: 4.535 ± 0.061	1.234IleHis: 1.234 ± 0.03	3.36IleIle: 3.36 ± 0.057	3.205IleLys: 3.205 ± 0.056	5.115IleLeu: 5.115 ± 0.069	1.302IleMet: 1.302 ± 0.029	3.129IleAsn: 3.129 ± 0.049	2.531IlePro: 2.531 ± 0.041	2.279IleGln: 2.279 ± 0.039	2.672IleArg: 2.672 ± 0.04	4.72IleSer: 4.72 ± 0.053	3.635IleThr: 3.635 ± 0.079	3.967IleVal: 3.967 ± 0.058	0.633IleTrp: 0.633 ± 0.022	1.705IleTyr: 1.705 ± 0.036	0.0IleXaa: 0.0 ± 0.0
Lys	4.653LysAla: 4.653 ± 0.071	0.311LysCys: 0.311 ± 0.017	2.789LysAsp: 2.789 ± 0.049	2.969LysGlu: 2.969 ± 0.05	1.59LysPhe: 1.59 ± 0.034	3.23LysGly: 3.23 ± 0.05	1.308LysHis: 1.308 ± 0.028	2.941LysIle: 2.941 ± 0.051	2.679LysLys: 2.679 ± 0.05	4.916LysLeu: 4.916 ± 0.073	1.363LysMet: 1.363 ± 0.035	2.294LysAsn: 2.294 ± 0.047	2.155LysPro: 2.155 ± 0.045	2.779LysGln: 2.779 ± 0.043	2.88LysArg: 2.88 ± 0.047	3.257LysSer: 3.257 ± 0.056	2.804LysThr: 2.804 ± 0.046	3.585LysVal: 3.585 ± 0.057	0.629LysTrp: 0.629 ± 0.022	1.357LysTyr: 1.357 ± 0.028	0.0LysXaa: 0.0 ± 0.0
Leu	10.004LeuAla: 10.004 ± 0.096	1.057LeuCys: 1.057 ± 0.028	5.723LeuAsp: 5.723 ± 0.065	5.208LeuGlu: 5.208 ± 0.066	4.174LeuPhe: 4.174 ± 0.066	7.019LeuGly: 7.019 ± 0.071	2.213LeuHis: 2.213 ± 0.043	5.904LeuIle: 5.904 ± 0.067	4.838LeuLys: 4.838 ± 0.068	10.241LeuLeu: 10.241 ± 0.125	2.451LeuMet: 2.451 ± 0.041	4.831LeuAsn: 4.831 ± 0.058	4.571LeuPro: 4.571 ± 0.055	3.91LeuGln: 3.91 ± 0.056	4.361LeuArg: 4.361 ± 0.068	7.965LeuSer: 7.965 ± 0.079	6.178LeuThr: 6.178 ± 0.083	6.813LeuVal: 6.813 ± 0.068	1.036LeuTrp: 1.036 ± 0.028	2.646LeuTyr: 2.646 ± 0.05	0.0LeuXaa: 0.0 ± 0.0
Met	2.33MetAla: 2.33 ± 0.047	0.238MetCys: 0.238 ± 0.013	1.159MetAsp: 1.159 ± 0.029	0.995MetGlu: 0.995 ± 0.026	0.942MetPhe: 0.942 ± 0.025	1.746MetGly: 1.746 ± 0.037	0.574MetHis: 0.574 ± 0.02	1.314MetIle: 1.314 ± 0.032	1.269MetLys: 1.269 ± 0.03	2.925MetLeu: 2.925 ± 0.046	0.69MetMet: 0.69 ± 0.027	1.135MetAsn: 1.135 ± 0.028	1.288MetPro: 1.288 ± 0.032	1.407MetGln: 1.407 ± 0.031	1.268MetArg: 1.268 ± 0.03	1.963MetSer: 1.963 ± 0.033	1.478MetThr: 1.478 ± 0.033	1.541MetVal: 1.541 ± 0.036	0.252MetTrp: 0.252 ± 0.015	0.577MetTyr: 0.577 ± 0.023	0.0MetXaa: 0.0 ± 0.0
Asn	3.961AsnAla: 3.961 ± 0.056	0.386AsnCys: 0.386 ± 0.016	2.726AsnAsp: 2.726 ± 0.048	2.576AsnGlu: 2.576 ± 0.047	1.673AsnPhe: 1.673 ± 0.034	3.216AsnGly: 3.216 ± 0.052	0.926AsnHis: 0.926 ± 0.025	3.043AsnIle: 3.043 ± 0.049	2.291AsnLys: 2.291 ± 0.04	4.054AsnLeu: 4.054 ± 0.061	1.083AsnMet: 1.083 ± 0.029	2.18AsnAsn: 2.18 ± 0.049	2.034AsnPro: 2.034 ± 0.044	2.152AsnGln: 2.152 ± 0.043	1.989AsnArg: 1.989 ± 0.036	2.891AsnSer: 2.891 ± 0.082	2.594AsnThr: 2.594 ± 0.043	3.125AsnVal: 3.125 ± 0.041	0.67AsnTrp: 0.67 ± 0.024	1.42AsnTyr: 1.42 ± 0.037	0.0AsnXaa: 0.0 ± 0.0
Pro	3.096ProAla: 3.096 ± 0.05	0.302ProCys: 0.302 ± 0.015	2.629ProAsp: 2.629 ± 0.047	2.994ProGlu: 2.994 ± 0.049	1.754ProPhe: 1.754 ± 0.039	2.341ProGly: 2.341 ± 0.048	0.844ProHis: 0.844 ± 0.027	2.579ProIle: 2.579 ± 0.04	2.08ProLys: 2.08 ± 0.041	3.926ProLeu: 3.926 ± 0.051	0.995ProMet: 0.995 ± 0.024	1.92ProAsn: 1.92 ± 0.036	1.242ProPro: 1.242 ± 0.036	1.75ProGln: 1.75 ± 0.035	1.378ProArg: 1.378 ± 0.031	2.786ProSer: 2.786 ± 0.047	2.056ProThr: 2.056 ± 0.048	2.969ProVal: 2.969 ± 0.053	0.53ProTrp: 0.53 ± 0.019	1.222ProTyr: 1.222 ± 0.028	0.0ProXaa: 0.0 ± 0.0
Gln	4.586GlnAla: 4.586 ± 0.067	0.402GlnCys: 0.402 ± 0.016	2.45GlnAsp: 2.45 ± 0.044	2.454GlnGlu: 2.454 ± 0.041	1.921GlnPhe: 1.921 ± 0.037	3.193GlnGly: 3.193 ± 0.049	1.423GlnHis: 1.423 ± 0.031	2.633GlnIle: 2.633 ± 0.043	2.228GlnLys: 2.228 ± 0.045	4.883GlnLeu: 4.883 ± 0.071	1.067GlnMet: 1.067 ± 0.032	1.985GlnAsn: 1.985 ± 0.038	1.789GlnPro: 1.789 ± 0.035	3.31GlnGln: 3.31 ± 0.068	2.469GlnArg: 2.469 ± 0.045	3.125GlnSer: 3.125 ± 0.052	2.497GlnThr: 2.497 ± 0.04	3.108GlnVal: 3.108 ± 0.052	0.686GlnTrp: 0.686 ± 0.023	1.541GlnTyr: 1.541 ± 0.034	0.0GlnXaa: 0.0 ± 0.0
Arg	3.486ArgAla: 3.486 ± 0.053	0.429ArgCys: 0.429 ± 0.019	2.455ArgAsp: 2.455 ± 0.041	2.605ArgGlu: 2.605 ± 0.045	2.333ArgPhe: 2.333 ± 0.045	2.57ArgGly: 2.57 ± 0.042	1.069ArgHis: 1.069 ± 0.029	2.875ArgIle: 2.875 ± 0.041	2.189ArgLys: 2.189 ± 0.051	4.678ArgLeu: 4.678 ± 0.069	1.135ArgMet: 1.135 ± 0.026	1.894ArgAsn: 1.894 ± 0.033	1.575ArgPro: 1.575 ± 0.04	2.146ArgGln: 2.146 ± 0.046	2.116ArgArg: 2.116 ± 0.038	2.689ArgSer: 2.689 ± 0.045	2.121ArgThr: 2.121 ± 0.041	3.171ArgVal: 3.171 ± 0.049	0.632ArgTrp: 0.632 ± 0.022	1.761ArgTyr: 1.761 ± 0.031	0.0ArgXaa: 0.0 ± 0.0
Ser	6.466SerAla: 6.466 ± 0.067	0.6SerCys: 0.6 ± 0.023	4.078SerAsp: 4.078 ± 0.076	3.985SerGlu: 3.985 ± 0.058	2.88SerPhe: 2.88 ± 0.05	5.095SerGly: 5.095 ± 0.067	1.601SerHis: 1.601 ± 0.031	4.379SerIle: 4.379 ± 0.061	3.292SerLys: 3.292 ± 0.054	7.048SerLeu: 7.048 ± 0.082	1.704SerMet: 1.704 ± 0.036	2.859SerAsn: 2.859 ± 0.055	2.705SerPro: 2.705 ± 0.044	3.247SerGln: 3.247 ± 0.045	2.942SerArg: 2.942 ± 0.047	4.738SerSer: 4.738 ± 0.067	3.554SerThr: 3.554 ± 0.064	5.097SerVal: 5.097 ± 0.065	0.812SerTrp: 0.812 ± 0.024	2.034SerTyr: 2.034 ± 0.047	0.0SerXaa: 0.0 ± 0.0
Thr	4.51ThrAla: 4.51 ± 0.067	0.458ThrCys: 0.458 ± 0.02	3.334ThrAsp: 3.334 ± 0.072	2.932ThrGlu: 2.932 ± 0.047	2.329ThrPhe: 2.329 ± 0.039	4.181ThrGly: 4.181 ± 0.073	1.38ThrHis: 1.38 ± 0.033	3.128ThrIle: 3.128 ± 0.062	2.275ThrLys: 2.275 ± 0.043	6.439ThrLeu: 6.439 ± 0.08	1.117ThrMet: 1.117 ± 0.029	2.059ThrAsn: 2.059 ± 0.043	2.818ThrPro: 2.818 ± 0.048	2.804ThrGln: 2.804 ± 0.05	2.248ThrArg: 2.248 ± 0.043	3.691ThrSer: 3.691 ± 0.053	2.878ThrThr: 2.878 ± 0.064	3.895ThrVal: 3.895 ± 0.137	0.625ThrTrp: 0.625 ± 0.019	1.678ThrTyr: 1.678 ± 0.038	0.0ThrXaa: 0.0 ± 0.0
Val	6.314ValAla: 6.314 ± 0.074	0.728ValCys: 0.728 ± 0.025	4.295ValAsp: 4.295 ± 0.078	4.107ValGlu: 4.107 ± 0.053	2.977ValPhe: 2.977 ± 0.045	4.544ValGly: 4.544 ± 0.059	1.349ValHis: 1.349 ± 0.03	4.461ValIle: 4.461 ± 0.057	3.551ValLys: 3.551 ± 0.054	6.756ValLeu: 6.756 ± 0.066	1.831ValMet: 1.831 ± 0.034	3.323ValAsn: 3.323 ± 0.048	2.704ValPro: 2.704 ± 0.051	2.462ValGln: 2.462 ± 0.049	2.79ValArg: 2.79 ± 0.052	5.227ValSer: 5.227 ± 0.065	4.253ValThr: 4.253 ± 0.084	4.964ValVal: 4.964 ± 0.072	0.717ValTrp: 0.717 ± 0.022	1.782ValTyr: 1.782 ± 0.038	0.0ValXaa: 0.0 ± 0.0
Trp	0.884TrpAla: 0.884 ± 0.025	0.148TrpCys: 0.148 ± 0.009	0.641TrpAsp: 0.641 ± 0.023	0.516TrpGlu: 0.516 ± 0.022	0.588TrpPhe: 0.588 ± 0.021	0.798TrpGly: 0.798 ± 0.025	0.383TrpHis: 0.383 ± 0.017	0.633TrpIle: 0.633 ± 0.022	0.46TrpLys: 0.46 ± 0.018	1.717TrpLeu: 1.717 ± 0.041	0.316TrpMet: 0.316 ± 0.015	0.446TrpAsn: 0.446 ± 0.021	0.481TrpPro: 0.481 ± 0.017	1.089TrpGln: 1.089 ± 0.03	0.7TrpArg: 0.7 ± 0.022	0.708TrpSer: 0.708 ± 0.026	0.488TrpThr: 0.488 ± 0.019	0.853TrpVal: 0.853 ± 0.027	0.201TrpTrp: 0.201 ± 0.012	0.383TrpTyr: 0.383 ± 0.017	0.0TrpXaa: 0.0 ± 0.0
Tyr	2.652TyrAla: 2.652 ± 0.051	0.359TyrCys: 0.359 ± 0.015	1.736TyrAsp: 1.736 ± 0.039	1.617TyrGlu: 1.617 ± 0.036	1.623TyrPhe: 1.623 ± 0.04	2.047TyrGly: 2.047 ± 0.04	0.789TyrHis: 0.789 ± 0.024	1.641TyrIle: 1.641 ± 0.036	1.299TyrLys: 1.299 ± 0.035	3.269TyrLeu: 3.269 ± 0.049	0.652TyrMet: 0.652 ± 0.021	1.186TyrAsn: 1.186 ± 0.035	1.368TyrPro: 1.368 ± 0.035	1.951TyrGln: 1.951 ± 0.032	1.689TyrArg: 1.689 ± 0.034	2.146TyrSer: 2.146 ± 0.046	1.603TyrThr: 1.603 ± 0.04	1.907TyrVal: 1.907 ± 0.035	0.466TyrTrp: 0.466 ± 0.017	1.076TyrTyr: 1.076 ± 0.029	0.0TyrXaa: 0.0 ± 0.0
Xaa	0.0XaaAla: 0.0 ± 0.0	0.0XaaCys: 0.0 ± 0.0	0.0XaaAsp: 0.0 ± 0.0	0.0XaaGlu: 0.0 ± 0.0	0.0XaaPhe: 0.0 ± 0.0	0.0XaaGly: 0.0 ± 0.0	0.0XaaHis: 0.0 ± 0.0	0.0XaaIle: 0.0 ± 0.0	0.0XaaLys: 0.0 ± 0.0	0.0XaaLeu: 0.0 ± 0.0	0.0XaaMet: 0.0 ± 0.0	0.0XaaAsn: 0.0 ± 0.0	0.0XaaPro: 0.0 ± 0.0	0.0XaaGln: 0.0 ± 0.0	0.0XaaArg: 0.0 ± 0.0	0.0XaaSer: 0.0 ± 0.0	0.0XaaThr: 0.0 ± 0.0	0.0XaaVal: 0.0 ± 0.0	0.0XaaTrp: 0.0 ± 0.0	0.0XaaTyr: 0.0 ± 0.0	0.0XaaXaa: 0.0 ± 0.0

Statistics based on 4271 proteins (1485885 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944

Contact: Lukasz P. Kozlowski

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