Amino acid dipepetide frequency for Odrenisrou virus

Apart from single amino acid frequencies one can also calculate so called amino acid dipeptide frequency.

There is 400 possibilites (441 if we consider Xaa as additional 21st amino acid representing all non-standard or unknown amino acids). Thus, if the dipeptides would be present randomly in proteins each amino acid dipeptide should be present with 0.25% frequency. As it is not the case in the nature, for better visablity all more than expected dipepetides are marked by red, and those which are underrepresented are marked by blue in the table.

All values are presented as per milles (‰), therefore need to be multiplied by 10-3.

For more information see sequence space article on Wikipedia.

AlaCysAspGluPheGlyHisIleLysLeuMetAsnProGlnArgSerThrValTrpTyrXaa
Ala
2.36AlaAla: 2.36 ± 3.067
0.787AlaCys: 0.787 ± 0.241
1.573AlaAsp: 1.573 ± 0.588
1.835AlaGlu: 1.835 ± 0.422
1.049AlaPhe: 1.049 ± 0.362
1.573AlaGly: 1.573 ± 1.842
1.049AlaHis: 1.049 ± 1.228
4.195AlaIle: 4.195 ± 1.386
2.622AlaLys: 2.622 ± 2.534
6.555AlaLeu: 6.555 ± 2.282
2.098AlaMet: 2.098 ± 0.467
1.311AlaAsn: 1.311 ± 1.186
2.884AlaPro: 2.884 ± 0.699
1.311AlaGln: 1.311 ± 0.788
2.36AlaArg: 2.36 ± 0.866
3.408AlaSer: 3.408 ± 1.515
4.195AlaThr: 4.195 ± 0.831
3.146AlaVal: 3.146 ± 1.135
0.262AlaTrp: 0.262 ± 0.633
1.573AlaTyr: 1.573 ± 0.743
0.0AlaXaa: 0.0 ± 0.0
Cys
0.787CysAla: 0.787 ± 0.712
0.524CysCys: 0.524 ± 0.181
1.573CysAsp: 1.573 ± 0.482
1.049CysGlu: 1.049 ± 0.364
3.408CysPhe: 3.408 ± 1.341
0.524CysGly: 0.524 ± 0.474
1.049CysHis: 1.049 ± 0.622
0.0CysIle: 0.0 ± 0.0
3.146CysLys: 3.146 ± 0.626
2.884CysLeu: 2.884 ± 1.59
0.787CysMet: 0.787 ± 0.241
0.524CysAsn: 0.524 ± 0.312
0.524CysPro: 0.524 ± 0.181
1.311CysGln: 1.311 ± 0.856
1.835CysArg: 1.835 ± 0.805
3.146CysSer: 3.146 ± 1.513
1.573CysThr: 1.573 ± 0.402
1.573CysVal: 1.573 ± 0.588
0.262CysTrp: 0.262 ± 0.237
1.835CysTyr: 1.835 ± 1.013
0.0CysXaa: 0.0 ± 0.0
Asp
1.835AspAla: 1.835 ± 1.045
1.835AspCys: 1.835 ± 1.022
4.195AspAsp: 4.195 ± 1.804
3.408AspGlu: 3.408 ± 0.388
2.36AspPhe: 2.36 ± 1.017
2.098AspGly: 2.098 ± 0.437
1.573AspHis: 1.573 ± 0.482
3.408AspIle: 3.408 ± 1.306
3.146AspLys: 3.146 ± 0.543
4.982AspLeu: 4.982 ± 1.43
1.049AspMet: 1.049 ± 0.625
3.146AspAsn: 3.146 ± 0.27
3.671AspPro: 3.671 ± 1.538
2.36AspGln: 2.36 ± 1.112
1.573AspArg: 1.573 ± 0.528
5.768AspSer: 5.768 ± 1.671
2.36AspThr: 2.36 ± 0.557
3.146AspVal: 3.146 ± 0.804
0.524AspTrp: 0.524 ± 0.312
1.311AspTyr: 1.311 ± 1.085
0.0AspXaa: 0.0 ± 0.0
Glu
2.622GluAla: 2.622 ± 0.905
2.884GluCys: 2.884 ± 1.095
3.671GluAsp: 3.671 ± 0.234
7.079GluGlu: 7.079 ± 1.598
3.933GluPhe: 3.933 ± 1.362
4.195GluGly: 4.195 ± 0.814
0.787GluHis: 0.787 ± 0.392
5.244GluIle: 5.244 ± 1.524
2.622GluLys: 2.622 ± 0.835
6.03GluLeu: 6.03 ± 1.826
2.36GluMet: 2.36 ± 1.582
1.835GluAsn: 1.835 ± 0.485
2.098GluPro: 2.098 ± 0.437
0.524GluGln: 0.524 ± 0.474
3.146GluArg: 3.146 ± 0.634
3.146GluSer: 3.146 ± 1.444
3.933GluThr: 3.933 ± 0.634
3.933GluVal: 3.933 ± 1.581
1.049GluTrp: 1.049 ± 0.622
2.884GluTyr: 2.884 ± 0.869
0.0GluXaa: 0.0 ± 0.0
Phe
1.573PheAla: 1.573 ± 0.433
1.573PheCys: 1.573 ± 0.784
2.098PheAsp: 2.098 ± 0.943
1.311PheGlu: 1.311 ± 0.563
2.622PhePhe: 2.622 ± 0.506
2.622PheGly: 2.622 ± 0.835
1.573PheHis: 1.573 ± 0.484
2.098PheIle: 2.098 ± 0.727
2.884PheLys: 2.884 ± 0.959
3.671PheLeu: 3.671 ± 0.646
1.049PheMet: 1.049 ± 1.153
2.36PheAsn: 2.36 ± 0.504
2.36PhePro: 2.36 ± 1.582
1.311PheGln: 1.311 ± 0.448
3.146PheArg: 3.146 ± 0.968
4.195PheSer: 4.195 ± 2.056
2.36PheThr: 2.36 ± 0.83
3.146PheVal: 3.146 ± 0.642
0.787PheTrp: 0.787 ± 0.241
1.049PheTyr: 1.049 ± 0.362
0.0PheXaa: 0.0 ± 0.0
Gly
3.146GlyAla: 3.146 ± 1.499
1.049GlyCys: 1.049 ± 0.362
1.835GlyAsp: 1.835 ± 1.013
3.408GlyGlu: 3.408 ± 1.082
2.098GlyPhe: 2.098 ± 0.467
4.457GlyGly: 4.457 ± 0.978
1.573GlyHis: 1.573 ± 0.654
5.244GlyIle: 5.244 ± 1.545
3.408GlyLys: 3.408 ± 1.074
6.555GlyLeu: 6.555 ± 1.769
1.311GlyMet: 1.311 ± 0.657
2.36GlyAsn: 2.36 ± 1.157
2.36GlyPro: 2.36 ± 0.848
1.049GlyGln: 1.049 ± 0.5
3.408GlyArg: 3.408 ± 0.987
8.39GlySer: 8.39 ± 1.868
3.671GlyThr: 3.671 ± 1.736
3.933GlyVal: 3.933 ± 0.723
1.049GlyTrp: 1.049 ± 0.465
1.573GlyTyr: 1.573 ± 0.482
0.0GlyXaa: 0.0 ± 0.0
His
0.787HisAla: 0.787 ± 0.392
0.787HisCys: 0.787 ± 0.392
1.573HisAsp: 1.573 ± 0.402
0.787HisGlu: 0.787 ± 0.469
1.049HisPhe: 1.049 ± 0.362
2.884HisGly: 2.884 ± 1.344
0.524HisHis: 0.524 ± 0.312
2.098HisIle: 2.098 ± 0.631
1.049HisLys: 1.049 ± 0.364
2.622HisLeu: 2.622 ± 0.854
0.262HisMet: 0.262 ± 0.661
1.573HisAsn: 1.573 ± 0.484
1.573HisPro: 1.573 ± 0.654
1.311HisGln: 1.311 ± 0.397
1.573HisArg: 1.573 ± 0.654
2.36HisSer: 2.36 ± 1.11
1.049HisThr: 1.049 ± 0.364
1.311HisVal: 1.311 ± 0.397
0.0HisTrp: 0.0 ± 0.0
0.524HisTyr: 0.524 ± 0.181
0.0HisXaa: 0.0 ± 0.0
Ile
2.884IleAla: 2.884 ± 1.014
1.049IleCys: 1.049 ± 0.594
4.719IleAsp: 4.719 ± 2.06
5.244IleGlu: 5.244 ± 0.627
3.408IlePhe: 3.408 ± 1.043
3.408IleGly: 3.408 ± 1.393
1.311IleHis: 1.311 ± 0.448
3.146IleIle: 3.146 ± 0.628
2.622IleLys: 2.622 ± 0.51
7.341IleLeu: 7.341 ± 0.779
2.098IleMet: 2.098 ± 0.467
2.622IleAsn: 2.622 ± 0.473
3.146IlePro: 3.146 ± 1.091
2.884IleGln: 2.884 ± 1.095
4.457IleArg: 4.457 ± 1.811
6.555IleSer: 6.555 ± 1.429
3.408IleThr: 3.408 ± 1.275
3.408IleVal: 3.408 ± 0.397
0.262IleTrp: 0.262 ± 0.156
1.573IleTyr: 1.573 ± 0.792
0.0IleXaa: 0.0 ± 0.0
Lys
3.408LysAla: 3.408 ± 0.623
2.622LysCys: 2.622 ± 0.905
3.408LysAsp: 3.408 ± 0.388
3.146LysGlu: 3.146 ± 0.896
1.573LysPhe: 1.573 ± 0.482
1.835LysGly: 1.835 ± 0.568
1.573LysHis: 1.573 ± 0.784
4.195LysIle: 4.195 ± 0.874
4.457LysLys: 4.457 ± 1.115
7.079LysLeu: 7.079 ± 1.675
1.049LysMet: 1.049 ± 0.636
1.835LysAsn: 1.835 ± 0.805
2.622LysPro: 2.622 ± 0.473
2.622LysGln: 2.622 ± 1.1
3.408LysArg: 3.408 ± 1.072
4.457LysSer: 4.457 ± 0.845
3.671LysThr: 3.671 ± 1.301
6.817LysVal: 6.817 ± 1.519
0.787LysTrp: 0.787 ± 0.469
2.098LysTyr: 2.098 ± 0.649
0.0LysXaa: 0.0 ± 0.0
Leu
5.506LeuAla: 5.506 ± 1.945
2.622LeuCys: 2.622 ± 0.926
5.506LeuAsp: 5.506 ± 2.49
6.555LeuGlu: 6.555 ± 1.508
4.195LeuPhe: 4.195 ± 1.339
6.03LeuGly: 6.03 ± 1.218
2.36LeuHis: 2.36 ± 1.117
6.555LeuIle: 6.555 ± 1.735
6.555LeuLys: 6.555 ± 2.561
6.817LeuLeu: 6.817 ± 1.039
2.622LeuMet: 2.622 ± 0.396
2.36LeuAsn: 2.36 ± 0.399
2.622LeuPro: 2.622 ± 0.667
4.195LeuGln: 4.195 ± 1.886
6.817LeuArg: 6.817 ± 2.338
11.536LeuSer: 11.536 ± 0.618
4.982LeuThr: 4.982 ± 0.442
4.719LeuVal: 4.719 ± 1.373
0.524LeuTrp: 0.524 ± 0.181
4.982LeuTyr: 4.982 ± 0.334
0.0LeuXaa: 0.0 ± 0.0
Met
0.787MetAla: 0.787 ± 0.529
0.262MetCys: 0.262 ± 0.156
2.884MetAsp: 2.884 ± 1.576
2.36MetGlu: 2.36 ± 1.697
1.049MetPhe: 1.049 ± 0.465
2.622MetGly: 2.622 ± 0.961
1.311MetHis: 1.311 ± 0.495
1.311MetIle: 1.311 ± 0.701
2.098MetLys: 2.098 ± 1.945
1.311MetLeu: 1.311 ± 0.397
2.098MetMet: 2.098 ± 0.931
1.049MetAsn: 1.049 ± 0.594
0.262MetPro: 0.262 ± 0.633
0.787MetGln: 0.787 ± 0.241
2.098MetArg: 2.098 ± 0.415
1.573MetSer: 1.573 ± 1.378
1.835MetThr: 1.835 ± 0.568
1.573MetVal: 1.573 ± 0.543
0.262MetTrp: 0.262 ± 0.156
0.787MetTyr: 0.787 ± 0.392
0.0MetXaa: 0.0 ± 0.0
Asn
2.098AsnAla: 2.098 ± 0.415
1.049AsnCys: 1.049 ± 0.58
1.835AsnAsp: 1.835 ± 0.862
1.311AsnGlu: 1.311 ± 0.505
2.622AsnPhe: 2.622 ± 0.667
3.146AsnGly: 3.146 ± 0.867
0.787AsnHis: 0.787 ± 0.241
1.835AsnIle: 1.835 ± 0.597
1.835AsnLys: 1.835 ± 0.605
5.244AsnLeu: 5.244 ± 1.71
0.787AsnMet: 0.787 ± 0.578
1.573AsnAsn: 1.573 ± 0.482
1.573AsnPro: 1.573 ± 0.433
1.049AsnGln: 1.049 ± 0.625
1.049AsnArg: 1.049 ± 0.364
4.719AsnSer: 4.719 ± 1.239
1.049AsnThr: 1.049 ± 0.362
2.36AsnVal: 2.36 ± 0.743
0.524AsnTrp: 0.524 ± 0.312
1.573AsnTyr: 1.573 ± 1.11
0.0AsnXaa: 0.0 ± 0.0
Pro
0.787ProAla: 0.787 ± 0.392
0.524ProCys: 0.524 ± 0.627
2.36ProAsp: 2.36 ± 0.866
3.146ProGlu: 3.146 ± 1.503
0.787ProPhe: 0.787 ± 0.529
2.36ProGly: 2.36 ± 0.507
1.573ProHis: 1.573 ± 0.784
3.146ProIle: 3.146 ± 0.33
1.573ProLys: 1.573 ± 0.543
3.671ProLeu: 3.671 ± 1.456
0.787ProMet: 0.787 ± 0.605
1.835ProAsn: 1.835 ± 0.605
0.524ProPro: 0.524 ± 0.614
2.098ProGln: 2.098 ± 0.415
1.573ProArg: 1.573 ± 0.433
4.719ProSer: 4.719 ± 1.487
4.195ProThr: 4.195 ± 1.353
3.408ProVal: 3.408 ± 0.397
1.049ProTrp: 1.049 ± 0.895
1.049ProTyr: 1.049 ± 0.465
0.0ProXaa: 0.0 ± 0.0
Gln
3.146GlnAla: 3.146 ± 2.275
1.049GlnCys: 1.049 ± 0.362
1.573GlnAsp: 1.573 ± 0.402
2.098GlnGlu: 2.098 ± 0.467
1.049GlnPhe: 1.049 ± 1.16
1.311GlnGly: 1.311 ± 0.505
1.835GlnHis: 1.835 ± 0.422
3.671GlnIle: 3.671 ± 0.506
3.146GlnLys: 3.146 ± 0.543
1.573GlnLeu: 1.573 ± 0.722
0.524GlnMet: 0.524 ± 0.181
1.049GlnAsn: 1.049 ± 0.593
1.835GlnPro: 1.835 ± 0.597
1.311GlnGln: 1.311 ± 0.474
0.524GlnArg: 0.524 ± 0.181
2.098GlnSer: 2.098 ± 0.554
0.787GlnThr: 0.787 ± 0.241
2.098GlnVal: 2.098 ± 0.631
0.262GlnTrp: 0.262 ± 0.633
1.311GlnTyr: 1.311 ± 0.563
0.0GlnXaa: 0.0 ± 0.0
Arg
3.146ArgAla: 3.146 ± 0.946
1.049ArgCys: 1.049 ± 0.622
4.457ArgAsp: 4.457 ± 1.868
2.884ArgGlu: 2.884 ± 1.065
1.573ArgPhe: 1.573 ± 0.402
4.719ArgGly: 4.719 ± 0.945
0.524ArgHis: 0.524 ± 0.181
3.146ArgIle: 3.146 ± 0.33
2.098ArgLys: 2.098 ± 1.25
4.195ArgLeu: 4.195 ± 1.136
2.098ArgMet: 2.098 ± 0.709
2.098ArgAsn: 2.098 ± 0.631
2.884ArgPro: 2.884 ± 0.869
1.573ArgGln: 1.573 ± 0.722
2.098ArgArg: 2.098 ± 0.415
5.768ArgSer: 5.768 ± 1.084
1.835ArgThr: 1.835 ± 1.094
3.671ArgVal: 3.671 ± 0.163
1.049ArgTrp: 1.049 ± 0.594
1.049ArgTyr: 1.049 ± 0.625
0.0ArgXaa: 0.0 ± 0.0
Ser
6.293SerAla: 6.293 ± 0.541
3.933SerCys: 3.933 ± 2.874
3.933SerAsp: 3.933 ± 1.051
6.555SerGlu: 6.555 ± 0.838
6.03SerPhe: 6.03 ± 0.554
7.079SerGly: 7.079 ± 1.566
1.311SerHis: 1.311 ± 0.397
5.506SerIle: 5.506 ± 0.854
5.768SerLys: 5.768 ± 1.386
11.799SerLeu: 11.799 ± 1.209
3.146SerMet: 3.146 ± 0.804
2.622SerAsn: 2.622 ± 0.667
4.982SerPro: 4.982 ± 0.442
2.622SerGln: 2.622 ± 0.51
4.457SerArg: 4.457 ± 1.05
12.585SerSer: 12.585 ± 1.286
2.36SerThr: 2.36 ± 0.557
5.768SerVal: 5.768 ± 1.84
1.835SerTrp: 1.835 ± 0.568
1.049SerTyr: 1.049 ± 0.58
0.0SerXaa: 0.0 ± 0.0
Thr
1.835ThrAla: 1.835 ± 0.498
0.524ThrCys: 0.524 ± 0.181
2.098ThrAsp: 2.098 ± 0.631
3.671ThrGlu: 3.671 ± 0.94
0.787ThrPhe: 0.787 ± 0.241
3.408ThrGly: 3.408 ± 0.16
1.311ThrHis: 1.311 ± 0.505
4.195ThrIle: 4.195 ± 1.31
4.457ThrLys: 4.457 ± 0.978
6.03ThrLeu: 6.03 ± 0.666
1.049ThrMet: 1.049 ± 0.877
1.835ThrAsn: 1.835 ± 0.597
2.36ThrPro: 2.36 ± 0.399
2.622ThrGln: 2.622 ± 0.948
2.622ThrArg: 2.622 ± 0.783
4.982ThrSer: 4.982 ± 1.554
2.36ThrThr: 2.36 ± 0.743
3.671ThrVal: 3.671 ± 1.955
0.262ThrTrp: 0.262 ± 0.661
1.835ThrTyr: 1.835 ± 0.568
0.0ThrXaa: 0.0 ± 0.0
Val
1.049ValAla: 1.049 ± 0.5
2.622ValCys: 2.622 ± 1.063
2.622ValAsp: 2.622 ± 0.744
5.244ValGlu: 5.244 ± 0.998
2.098ValPhe: 2.098 ± 0.953
4.457ValGly: 4.457 ± 1.359
2.36ValHis: 2.36 ± 0.916
3.671ValIle: 3.671 ± 1.231
6.03ValLys: 6.03 ± 1.878
5.768ValLeu: 5.768 ± 0.824
2.098ValMet: 2.098 ± 0.457
2.622ValAsn: 2.622 ± 0.63
1.311ValPro: 1.311 ± 1.784
1.311ValGln: 1.311 ± 0.49
3.933ValArg: 3.933 ± 0.97
5.768ValSer: 5.768 ± 1.315
3.671ValThr: 3.671 ± 0.807
4.195ValVal: 4.195 ± 1.173
1.835ValTrp: 1.835 ± 0.597
1.049ValTyr: 1.049 ± 0.594
0.0ValXaa: 0.0 ± 0.0
Trp
0.262TrpAla: 0.262 ± 0.237
0.524TrpCys: 0.524 ± 0.312
0.524TrpAsp: 0.524 ± 0.58
1.049TrpGlu: 1.049 ± 0.362
0.524TrpPhe: 0.524 ± 0.181
1.049TrpGly: 1.049 ± 1.153
0.0TrpHis: 0.0 ± 0.0
1.311TrpIle: 1.311 ± 0.781
0.524TrpLys: 0.524 ± 0.645
1.311TrpLeu: 1.311 ± 0.397
0.262TrpMet: 0.262 ± 0.156
1.049TrpAsn: 1.049 ± 0.364
0.524TrpPro: 0.524 ± 0.58
0.0TrpGln: 0.0 ± 0.0
0.787TrpArg: 0.787 ± 0.566
0.787TrpSer: 0.787 ± 0.241
1.311TrpThr: 1.311 ± 0.49
0.524TrpVal: 0.524 ± 0.181
0.262TrpTrp: 0.262 ± 0.156
0.262TrpTyr: 0.262 ± 0.156
0.0TrpXaa: 0.0 ± 0.0
Tyr
1.835TyrAla: 1.835 ± 1.045
1.049TyrCys: 1.049 ± 0.622
1.311TyrAsp: 1.311 ± 1.085
1.835TyrGlu: 1.835 ± 0.568
1.573TyrPhe: 1.573 ± 0.654
2.098TyrGly: 2.098 ± 0.631
1.311TyrHis: 1.311 ± 0.397
1.573TyrIle: 1.573 ± 0.484
2.622TyrLys: 2.622 ± 0.744
2.622TyrLeu: 2.622 ± 0.783
0.524TyrMet: 0.524 ± 0.181
2.36TyrAsn: 2.36 ± 0.908
1.049TyrPro: 1.049 ± 0.593
0.0TyrGln: 0.0 ± 0.0
1.049TyrArg: 1.049 ± 0.362
3.671TyrSer: 3.671 ± 0.94
1.311TyrThr: 1.311 ± 0.505
1.573TyrVal: 1.573 ± 0.482
0.0TyrTrp: 0.0 ± 0.0
1.049TyrTyr: 1.049 ± 0.465
0.0TyrXaa: 0.0 ± 0.0
Xaa
0.0XaaAla: 0.0 ± 0.0
0.0XaaCys: 0.0 ± 0.0
0.0XaaAsp: 0.0 ± 0.0
0.0XaaGlu: 0.0 ± 0.0
0.0XaaPhe: 0.0 ± 0.0
0.0XaaGly: 0.0 ± 0.0
0.0XaaHis: 0.0 ± 0.0
0.0XaaIle: 0.0 ± 0.0
0.0XaaLys: 0.0 ± 0.0
0.0XaaLeu: 0.0 ± 0.0
0.0XaaMet: 0.0 ± 0.0
0.0XaaAsn: 0.0 ± 0.0
0.0XaaPro: 0.0 ± 0.0
0.0XaaGln: 0.0 ± 0.0
0.0XaaArg: 0.0 ± 0.0
0.0XaaSer: 0.0 ± 0.0
0.0XaaThr: 0.0 ± 0.0
0.0XaaVal: 0.0 ± 0.0
0.0XaaTrp: 0.0 ± 0.0
0.0XaaTyr: 0.0 ± 0.0
0.0XaaXaa: 0.0 ± 0.0
Statistics based on 4 proteins (3815 amino acids)

Note: The error has been estimated with the bootstraping (x100) at the protein level

Above dipeptide statistics (among other stats for this proteome) you can download from this CSV file
See this proteome in: uniprot_link
Proteome-pI is available under Creative Commons Attribution-NoDerivs license, for more details see here

Reference: Kozlowski LP. Proteome-pI 2.0: Proteome Isoelectric Point Database Update. Nucleic Acids Res. 2021, doi: 10.1093/nar/gkab944 Contact: Lukasz P. Kozlowski